Search of human proteins with 4503055

Search of human proteins with 4503055

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503055 crystallin, alpha A [Homo sapiens]
         (173 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503055 crystallin, alpha A [Homo sapiens]                         357   3e-99
gi|4503057 crystallin, alpha B [Homo sapiens]                         188   2e-48
gi|21389433 heat shock protein, alpha-crystallin-related, B6 [Ho...   130   6e-31
gi|4504517 heat shock protein beta-1 [Homo sapiens]                   108   2e-24
gi|4504519 heat shock 27kDa protein 2 [Homo sapiens]                   94   6e-20
gi|7657146 heat shock 22kDa protein 8 [Homo sapiens]                   67   1e-11
gi|5453688 heat shock 27kDa protein 3 [Homo sapiens]                   65   2e-11
gi|7657202 cardiovascular heat shock protein [Homo sapiens]            46   1e-05
gi|15082238 heat shock protein, alpha-crystallin-related, B9 [Ho...    45   4e-05
gi|53828920 phosphatidylinositol-specific phospholipase C, X dom...    29   1.8  
gi|88703041 sorting nexin 6 isoform b [Homo sapiens]                   28   4.0  
gi|4502833 neuronal nicotinic acetylcholine receptor beta 2 prec...    27   6.7  
gi|39995080 hypothetical protein LOC79567 [Homo sapiens]               27   6.7  

>gi|4503055 crystallin, alpha A [Homo sapiens]
          Length = 173

 Score =  357 bits (916), Expect = 3e-99
 Identities = 173/173 (100%), Positives = 173/173 (100%)

Query: 1   MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG 60
           MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG
Sbjct: 1   MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG 60

Query: 61  ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL 120
           ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL
Sbjct: 61  ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL 120

Query: 121 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS 173
           PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
Sbjct: 121 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS 173


>gi|4503057 crystallin, alpha B [Homo sapiens]
          Length = 175

 Score =  188 bits (477), Expect = 2e-48
 Identities = 97/178 (54%), Positives = 130/178 (73%), Gaps = 12/178 (6%)

Query: 1   MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFRTV- 56
           MD+ I HPW +R   PF+ PSRLFDQFFGE L E DL P  S+++SP+Y +  S  R   
Sbjct: 1   MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS 59

Query: 57  -LDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH 115
             D+G+SE+R ++D+F + LDVKHFSPE+L VKV  D +E+HGKH ERQD+HG+ISREFH
Sbjct: 60  WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH 119

Query: 116 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAP 171
           R+YR+P++VD   ++ SLS+DG+LT  GP+ Q     +  ER IP++REEKP  T+AP
Sbjct: 120 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQ----VSGPERTIPITREEKPAVTAAP 173


>gi|21389433 heat shock protein, alpha-crystallin-related, B6 [Homo
           sapiens]
          Length = 160

 Score =  130 bits (327), Expect = 6e-31
 Identities = 63/142 (44%), Positives = 93/142 (65%), Gaps = 7/142 (4%)

Query: 3   VTIQHPWFKRTLGPF----YPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLD 58
           V +Q  W +R   P      P RLFDQ FGEGL E +L     +T++PYY ++     + 
Sbjct: 5   VPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYLRA---PSVA 61

Query: 59  SGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRY 118
             +++V +D   F + LDVKHFSPE++ VKV  + VE+H +H ER D+HG+++REFHRRY
Sbjct: 62  LPVAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREFHRRY 121

Query: 119 RLPSNVDQSALSCSLSADGMLT 140
           RLP  VD +A++ +LS +G+L+
Sbjct: 122 RLPPGVDPAAVTSALSPEGVLS 143


>gi|4504517 heat shock protein beta-1 [Homo sapiens]
          Length = 205

 Score =  108 bits (271), Expect = 2e-24
 Identities = 69/170 (40%), Positives = 94/170 (55%), Gaps = 23/170 (13%)

Query: 17  FYP-SRLFDQFFGEGLFEYDLLPFLSST-------------------ISPYYRQSLFRTV 56
           +YP SRLFDQ FG      +   +L  +                    +P Y ++L R  
Sbjct: 22  WYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSRALSRQ- 80

Query: 57  LDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHR 116
           L SG+SE+R   D++ + LDV HF+P++LTVK +D  VEI GKH ERQD+HGYISR F R
Sbjct: 81  LSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTR 140

Query: 117 RYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEK 166
           +Y LP  VD + +S SLS +G LT   P  +    +   E  IPV+ E +
Sbjct: 141 KYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSN--EITIPVTFESR 188


>gi|4504519 heat shock 27kDa protein 2 [Homo sapiens]
          Length = 182

 Score = 94.0 bits (232), Expect = 6e-20
 Identities = 54/134 (40%), Positives = 78/134 (58%), Gaps = 1/134 (0%)

Query: 19  PSRLFDQFFGEGLFEYDLL-PFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDV 77
           PSRL +Q FGEGL   ++L P L        R +       +G SE+R    KF  FLDV
Sbjct: 21  PSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGSRAGASELRLSEGKFQAFLDV 80

Query: 78  KHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADG 137
            HF+P+++TV+  D+ +E+  +H +R D HG++SREF R Y LP++VD   +  +LS DG
Sbjct: 81  SHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDG 140

Query: 138 MLTFCGPKIQTGLD 151
           +L    P+    LD
Sbjct: 141 ILNLEAPRGGRHLD 154


>gi|7657146 heat shock 22kDa protein 8 [Homo sapiens]
          Length = 196

 Score = 66.6 bits (161), Expect = 1e-11
 Identities = 45/144 (31%), Positives = 69/144 (47%), Gaps = 17/144 (11%)

Query: 20  SRLFDQFFGEGLFEYDL--------LPFLSSTISPYYRQSLFRT---------VLDSGIS 62
           SRL D  FG   F  DL        LP LSS      R  +            V   G +
Sbjct: 28  SRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRT 87

Query: 63  EVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPS 122
                 + + + ++V  F PE+L VK +D +VE+ GKH E+Q + G +S+ F ++ +LP+
Sbjct: 88  PPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPA 147

Query: 123 NVDQSALSCSLSADGMLTFCGPKI 146
            VD   +  SLS +G+L    P++
Sbjct: 148 EVDPVTVFASLSPEGLLIIEAPQV 171


>gi|5453688 heat shock 27kDa protein 3 [Homo sapiens]
          Length = 150

 Score = 65.5 bits (158), Expect = 2e-11
 Identities = 31/75 (41%), Positives = 45/75 (60%)

Query: 65  RSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNV 124
           R  +  F I LDV  F PED+ ++  + ++ I  +H  R D+HG+ISR F R+Y+LP  V
Sbjct: 65  REGKSHFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGV 124

Query: 125 DQSALSCSLSADGML 139
           +   LS  L  DG+L
Sbjct: 125 EIKDLSAVLCHDGIL 139


>gi|7657202 cardiovascular heat shock protein [Homo sapiens]
          Length = 170

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 60  GISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYR 119
           G   +++  D +   +DV+ FSPED+ V   ++ +E+     E+    G +   F  + +
Sbjct: 71  GAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSNNHIEVRA---EKLAADGTVMNTFAHKCQ 127

Query: 120 LPSNVDQSALSCSLSADGMLT 140
           LP +VD ++++ +L  DG LT
Sbjct: 128 LPEDVDPTSVTSALREDGSLT 148


>gi|15082238 heat shock protein, alpha-crystallin-related, B9 [Homo
           sapiens]
          Length = 159

 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 14/109 (12%)

Query: 54  RTVLDSGISEVRSD--RDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYI- 110
           R + DS  ++  +D  RD F + LD   F+PE+L V+V   ++ + G+      D   + 
Sbjct: 35  RLLRDSPAAQEDNDHARDGFQMKLDAHGFAPEELVVQVDGQWLMVTGQQQLDVRDPERVS 94

Query: 111 ---SREFHRRYRLPSNVDQSALSCSLSADGMLTFCG-------PKIQTG 149
              S++ HR+  LPSN+  +A++C L+  G L   G       P+ QTG
Sbjct: 95  YRMSQKVHRK-MLPSNLSPTAMTCCLTPSGQLWVRGQCVALALPEAQTG 142


>gi|53828920 phosphatidylinositol-specific phospholipase C, X domain
           containing 3 [Homo sapiens]
          Length = 321

 Score = 29.3 bits (64), Expect = 1.8
 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 3/37 (8%)

Query: 47  YYRQSLFRTVLDSGISEVRS---DRDKFVIFLDVKHF 80
           Y+   LF   ++ G+ E+ +   D  K V+FLD  HF
Sbjct: 111 YFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHF 147


>gi|88703041 sorting nexin 6 isoform b [Homo sapiens]
          Length = 418

 Score = 28.1 bits (61), Expect = 4.0
 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 5/59 (8%)

Query: 57  LDSGISEVRSDRDKFVIFLDVKHFSP-----EDLTVKVQDDFVEIHGKHNERQDDHGYI 110
           L   IS+  S+RDK    +  K   P     E   V+  ++F+ +H    E +D  GYI
Sbjct: 44  LQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYI 102


>gi|4502833 neuronal nicotinic acetylcholine receptor beta 2
           precursor [Homo sapiens]
          Length = 502

 Score = 27.3 bits (59), Expect = 6.7
 Identities = 14/44 (31%), Positives = 22/44 (50%)

Query: 67  DRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYI 110
           DR +  + L  +  S +D T   + D V + G+ NE  DD  Y+
Sbjct: 179 DRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNENPDDSTYV 222


>gi|39995080 hypothetical protein LOC79567 [Homo sapiens]
          Length = 1219

 Score = 27.3 bits (59), Expect = 6.7
 Identities = 12/29 (41%), Positives = 17/29 (58%)

Query: 113 EFHRRYRLPSNVDQSALSCSLSADGMLTF 141
           EF RR+ +P++  Q  +  S S  G LTF
Sbjct: 942 EFSRRWEIPASSAQEVVQFSASRPGFLTF 970


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,709,272
Number of Sequences: 37866
Number of extensions: 277340
Number of successful extensions: 591
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 572
Number of HSP's gapped (non-prelim): 14
length of query: 173
length of database: 18,247,518
effective HSP length: 95
effective length of query: 78
effective length of database: 14,650,248
effective search space: 1142719344
effective search space used: 1142719344
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.