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Search of human proteins with 4503015
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503015 copine III [Homo sapiens]
(537 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503015 copine III [Homo sapiens] 1095 0.0
gi|23397708 copine I isoform a [Homo sapiens] 746 0.0
gi|23397706 copine I isoform a [Homo sapiens] 746 0.0
gi|23397704 copine I isoform a [Homo sapiens] 746 0.0
gi|23397702 copine I isoform a [Homo sapiens] 746 0.0
gi|23397700 copine I isoform a [Homo sapiens] 746 0.0
gi|23397698 copine I isoform a [Homo sapiens] 746 0.0
gi|23397696 copine I isoform a [Homo sapiens] 746 0.0
gi|197333761 copine I isoform b [Homo sapiens] 746 0.0
gi|30181236 copine II [Homo sapiens] 724 0.0
gi|18677733 copine IV [Homo sapiens] 603 e-172
gi|25141328 copine 7 isoform a [Homo sapiens] 601 e-172
gi|5174421 copine 6 [Homo sapiens] 571 e-163
gi|25121972 copine VIII [Homo sapiens] 543 e-154
gi|25141323 copine V [Homo sapiens] 538 e-153
gi|88703066 copine-like protein [Homo sapiens] 511 e-145
gi|7656993 copine 7 isoform b [Homo sapiens] 505 e-143
gi|211059429 synaptotagmin II [Homo sapiens] 63 8e-10
gi|31543670 synaptotagmin II [Homo sapiens] 63 8e-10
gi|92859638 synaptotagmin V [Homo sapiens] 60 5e-09
gi|209447073 synaptotagmin I [Homo sapiens] 59 1e-08
gi|5032139 synaptotagmin I [Homo sapiens] 59 1e-08
gi|209447070 synaptotagmin I [Homo sapiens] 59 1e-08
gi|39752671 synaptotagmin X [Homo sapiens] 59 1e-08
gi|28376627 synaptotagmin IX [Homo sapiens] 56 9e-08
gi|238550198 synaptotagmin III [Homo sapiens] 55 2e-07
gi|238550196 synaptotagmin III [Homo sapiens] 55 2e-07
gi|14150054 synaptotagmin III [Homo sapiens] 55 2e-07
gi|45504376 synaptotagmin VI [Homo sapiens] 55 2e-07
gi|13384594 protein kinase C, gamma [Homo sapiens] 53 6e-07
>gi|4503015 copine III [Homo sapiens]
Length = 537
Score = 1095 bits (2833), Expect = 0.0
Identities = 537/537 (100%), Positives = 537/537 (100%)
Query: 1 MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFS 60
MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFS
Sbjct: 1 MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFS 60
Query: 61 KTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTG 120
KTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTG
Sbjct: 61 KTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTG 120
Query: 121 RPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRT 180
RPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRT
Sbjct: 121 RPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRT 180
Query: 181 EVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEAS 240
EVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEAS
Sbjct: 181 EVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEAS 240
Query: 241 RSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTG 300
RSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTG
Sbjct: 241 RSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTG 300
Query: 301 SNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHE 360
SNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHE
Sbjct: 301 SNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHE 360
Query: 361 FPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQY 420
FPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQY
Sbjct: 361 FPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQY 420
Query: 421 FVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGE 480
FVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGE
Sbjct: 421 FVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGE 480
Query: 481 VAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPATKQQKQ 537
VAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPATKQQKQ
Sbjct: 481 VAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPATKQQKQ 537
>gi|23397708 copine I isoform a [Homo sapiens]
Length = 537
Score = 746 bits (1926), Expect = 0.0
Identities = 356/540 (65%), Positives = 432/540 (80%), Gaps = 12/540 (2%)
Query: 3 AQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKT 62
A CVT V L++SC +L+DKDIGSKSDPLCVL + G W E+ RTER++NC +P+FSKT
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 63 FIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRP 122
++Y FE VQKL+FG+YDIDNKT EL DDDFLG EC+LGQIVSS+ LT PL++K G+P
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKP 121
Query: 123 AGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEV 182
AG+G+IT+SA+E+KDNRVV E+EAR LD KD GKSDP+LEF +Q DG W +V+R+EV
Sbjct: 122 AGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQ-GDGKWHLVYRSEV 180
Query: 183 VKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRS 242
+KNNLNP W+ F + + C G+ I+V+C DYD+DGSHDLIGTF T++ +L+
Sbjct: 181 IKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV--- 237
Query: 243 SPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSN 302
P EFECI+ +K+QKKKSYKNSG I VK C + E +FLDY+MGGCQ+NFTVGVDFTGSN
Sbjct: 238 -PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSN 296
Query: 303 GDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFP 362
GDP SPDSLHY+SP GVNEYL ALWSVG V+QDYD+DK+FPAFGFGAQ+PP WQVSHEF
Sbjct: 297 GDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFA 356
Query: 363 MNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFV 422
+NFNPSNPYC GIQGIV+AYR LPQ++LYGPTNF+PIINHVARFAA A Q TASQYF+
Sbjct: 357 LNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQYFM 416
Query: 423 LLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVA 482
LL++TDG +TD++ TR+A+V AS LPMS+IIVGVGGADF AME LD DGG L + G+ A
Sbjct: 417 LLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAA 476
Query: 483 IRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNT-----YKLLPP--KNPATKQQ 535
RDIVQFVP+R+FQNAP+EALAQ VLAE+P Q+V YF K LPP K+PA Q
Sbjct: 477 ARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQ 536
>gi|23397706 copine I isoform a [Homo sapiens]
Length = 537
Score = 746 bits (1926), Expect = 0.0
Identities = 356/540 (65%), Positives = 432/540 (80%), Gaps = 12/540 (2%)
Query: 3 AQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKT 62
A CVT V L++SC +L+DKDIGSKSDPLCVL + G W E+ RTER++NC +P+FSKT
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 63 FIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRP 122
++Y FE VQKL+FG+YDIDNKT EL DDDFLG EC+LGQIVSS+ LT PL++K G+P
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKP 121
Query: 123 AGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEV 182
AG+G+IT+SA+E+KDNRVV E+EAR LD KD GKSDP+LEF +Q DG W +V+R+EV
Sbjct: 122 AGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQ-GDGKWHLVYRSEV 180
Query: 183 VKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRS 242
+KNNLNP W+ F + + C G+ I+V+C DYD+DGSHDLIGTF T++ +L+
Sbjct: 181 IKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV--- 237
Query: 243 SPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSN 302
P EFECI+ +K+QKKKSYKNSG I VK C + E +FLDY+MGGCQ+NFTVGVDFTGSN
Sbjct: 238 -PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSN 296
Query: 303 GDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFP 362
GDP SPDSLHY+SP GVNEYL ALWSVG V+QDYD+DK+FPAFGFGAQ+PP WQVSHEF
Sbjct: 297 GDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFA 356
Query: 363 MNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFV 422
+NFNPSNPYC GIQGIV+AYR LPQ++LYGPTNF+PIINHVARFAA A Q TASQYF+
Sbjct: 357 LNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQYFM 416
Query: 423 LLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVA 482
LL++TDG +TD++ TR+A+V AS LPMS+IIVGVGGADF AME LD DGG L + G+ A
Sbjct: 417 LLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAA 476
Query: 483 IRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNT-----YKLLPP--KNPATKQQ 535
RDIVQFVP+R+FQNAP+EALAQ VLAE+P Q+V YF K LPP K+PA Q
Sbjct: 477 ARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQ 536
>gi|23397704 copine I isoform a [Homo sapiens]
Length = 537
Score = 746 bits (1926), Expect = 0.0
Identities = 356/540 (65%), Positives = 432/540 (80%), Gaps = 12/540 (2%)
Query: 3 AQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKT 62
A CVT V L++SC +L+DKDIGSKSDPLCVL + G W E+ RTER++NC +P+FSKT
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 63 FIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRP 122
++Y FE VQKL+FG+YDIDNKT EL DDDFLG EC+LGQIVSS+ LT PL++K G+P
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKP 121
Query: 123 AGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEV 182
AG+G+IT+SA+E+KDNRVV E+EAR LD KD GKSDP+LEF +Q DG W +V+R+EV
Sbjct: 122 AGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQ-GDGKWHLVYRSEV 180
Query: 183 VKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRS 242
+KNNLNP W+ F + + C G+ I+V+C DYD+DGSHDLIGTF T++ +L+
Sbjct: 181 IKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV--- 237
Query: 243 SPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSN 302
P EFECI+ +K+QKKKSYKNSG I VK C + E +FLDY+MGGCQ+NFTVGVDFTGSN
Sbjct: 238 -PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSN 296
Query: 303 GDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFP 362
GDP SPDSLHY+SP GVNEYL ALWSVG V+QDYD+DK+FPAFGFGAQ+PP WQVSHEF
Sbjct: 297 GDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFA 356
Query: 363 MNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFV 422
+NFNPSNPYC GIQGIV+AYR LPQ++LYGPTNF+PIINHVARFAA A Q TASQYF+
Sbjct: 357 LNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQYFM 416
Query: 423 LLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVA 482
LL++TDG +TD++ TR+A+V AS LPMS+IIVGVGGADF AME LD DGG L + G+ A
Sbjct: 417 LLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAA 476
Query: 483 IRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNT-----YKLLPP--KNPATKQQ 535
RDIVQFVP+R+FQNAP+EALAQ VLAE+P Q+V YF K LPP K+PA Q
Sbjct: 477 ARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQ 536
>gi|23397702 copine I isoform a [Homo sapiens]
Length = 537
Score = 746 bits (1926), Expect = 0.0
Identities = 356/540 (65%), Positives = 432/540 (80%), Gaps = 12/540 (2%)
Query: 3 AQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKT 62
A CVT V L++SC +L+DKDIGSKSDPLCVL + G W E+ RTER++NC +P+FSKT
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 63 FIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRP 122
++Y FE VQKL+FG+YDIDNKT EL DDDFLG EC+LGQIVSS+ LT PL++K G+P
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKP 121
Query: 123 AGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEV 182
AG+G+IT+SA+E+KDNRVV E+EAR LD KD GKSDP+LEF +Q DG W +V+R+EV
Sbjct: 122 AGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQ-GDGKWHLVYRSEV 180
Query: 183 VKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRS 242
+KNNLNP W+ F + + C G+ I+V+C DYD+DGSHDLIGTF T++ +L+
Sbjct: 181 IKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV--- 237
Query: 243 SPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSN 302
P EFECI+ +K+QKKKSYKNSG I VK C + E +FLDY+MGGCQ+NFTVGVDFTGSN
Sbjct: 238 -PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSN 296
Query: 303 GDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFP 362
GDP SPDSLHY+SP GVNEYL ALWSVG V+QDYD+DK+FPAFGFGAQ+PP WQVSHEF
Sbjct: 297 GDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFA 356
Query: 363 MNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFV 422
+NFNPSNPYC GIQGIV+AYR LPQ++LYGPTNF+PIINHVARFAA A Q TASQYF+
Sbjct: 357 LNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQYFM 416
Query: 423 LLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVA 482
LL++TDG +TD++ TR+A+V AS LPMS+IIVGVGGADF AME LD DGG L + G+ A
Sbjct: 417 LLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAA 476
Query: 483 IRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNT-----YKLLPP--KNPATKQQ 535
RDIVQFVP+R+FQNAP+EALAQ VLAE+P Q+V YF K LPP K+PA Q
Sbjct: 477 ARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQ 536
>gi|23397700 copine I isoform a [Homo sapiens]
Length = 537
Score = 746 bits (1926), Expect = 0.0
Identities = 356/540 (65%), Positives = 432/540 (80%), Gaps = 12/540 (2%)
Query: 3 AQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKT 62
A CVT V L++SC +L+DKDIGSKSDPLCVL + G W E+ RTER++NC +P+FSKT
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 63 FIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRP 122
++Y FE VQKL+FG+YDIDNKT EL DDDFLG EC+LGQIVSS+ LT PL++K G+P
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKP 121
Query: 123 AGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEV 182
AG+G+IT+SA+E+KDNRVV E+EAR LD KD GKSDP+LEF +Q DG W +V+R+EV
Sbjct: 122 AGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQ-GDGKWHLVYRSEV 180
Query: 183 VKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRS 242
+KNNLNP W+ F + + C G+ I+V+C DYD+DGSHDLIGTF T++ +L+
Sbjct: 181 IKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV--- 237
Query: 243 SPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSN 302
P EFECI+ +K+QKKKSYKNSG I VK C + E +FLDY+MGGCQ+NFTVGVDFTGSN
Sbjct: 238 -PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSN 296
Query: 303 GDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFP 362
GDP SPDSLHY+SP GVNEYL ALWSVG V+QDYD+DK+FPAFGFGAQ+PP WQVSHEF
Sbjct: 297 GDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFA 356
Query: 363 MNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFV 422
+NFNPSNPYC GIQGIV+AYR LPQ++LYGPTNF+PIINHVARFAA A Q TASQYF+
Sbjct: 357 LNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQYFM 416
Query: 423 LLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVA 482
LL++TDG +TD++ TR+A+V AS LPMS+IIVGVGGADF AME LD DGG L + G+ A
Sbjct: 417 LLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAA 476
Query: 483 IRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNT-----YKLLPP--KNPATKQQ 535
RDIVQFVP+R+FQNAP+EALAQ VLAE+P Q+V YF K LPP K+PA Q
Sbjct: 477 ARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQ 536
>gi|23397698 copine I isoform a [Homo sapiens]
Length = 537
Score = 746 bits (1926), Expect = 0.0
Identities = 356/540 (65%), Positives = 432/540 (80%), Gaps = 12/540 (2%)
Query: 3 AQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKT 62
A CVT V L++SC +L+DKDIGSKSDPLCVL + G W E+ RTER++NC +P+FSKT
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 63 FIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRP 122
++Y FE VQKL+FG+YDIDNKT EL DDDFLG EC+LGQIVSS+ LT PL++K G+P
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKP 121
Query: 123 AGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEV 182
AG+G+IT+SA+E+KDNRVV E+EAR LD KD GKSDP+LEF +Q DG W +V+R+EV
Sbjct: 122 AGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQ-GDGKWHLVYRSEV 180
Query: 183 VKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRS 242
+KNNLNP W+ F + + C G+ I+V+C DYD+DGSHDLIGTF T++ +L+
Sbjct: 181 IKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV--- 237
Query: 243 SPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSN 302
P EFECI+ +K+QKKKSYKNSG I VK C + E +FLDY+MGGCQ+NFTVGVDFTGSN
Sbjct: 238 -PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSN 296
Query: 303 GDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFP 362
GDP SPDSLHY+SP GVNEYL ALWSVG V+QDYD+DK+FPAFGFGAQ+PP WQVSHEF
Sbjct: 297 GDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFA 356
Query: 363 MNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFV 422
+NFNPSNPYC GIQGIV+AYR LPQ++LYGPTNF+PIINHVARFAA A Q TASQYF+
Sbjct: 357 LNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQYFM 416
Query: 423 LLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVA 482
LL++TDG +TD++ TR+A+V AS LPMS+IIVGVGGADF AME LD DGG L + G+ A
Sbjct: 417 LLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAA 476
Query: 483 IRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNT-----YKLLPP--KNPATKQQ 535
RDIVQFVP+R+FQNAP+EALAQ VLAE+P Q+V YF K LPP K+PA Q
Sbjct: 477 ARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQ 536
>gi|23397696 copine I isoform a [Homo sapiens]
Length = 537
Score = 746 bits (1926), Expect = 0.0
Identities = 356/540 (65%), Positives = 432/540 (80%), Gaps = 12/540 (2%)
Query: 3 AQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKT 62
A CVT V L++SC +L+DKDIGSKSDPLCVL + G W E+ RTER++NC +P+FSKT
Sbjct: 2 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 61
Query: 63 FIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRP 122
++Y FE VQKL+FG+YDIDNKT EL DDDFLG EC+LGQIVSS+ LT PL++K G+P
Sbjct: 62 LQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKP 121
Query: 123 AGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEV 182
AG+G+IT+SA+E+KDNRVV E+EAR LD KD GKSDP+LEF +Q DG W +V+R+EV
Sbjct: 122 AGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQ-GDGKWHLVYRSEV 180
Query: 183 VKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRS 242
+KNNLNP W+ F + + C G+ I+V+C DYD+DGSHDLIGTF T++ +L+
Sbjct: 181 IKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV--- 237
Query: 243 SPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSN 302
P EFECI+ +K+QKKKSYKNSG I VK C + E +FLDY+MGGCQ+NFTVGVDFTGSN
Sbjct: 238 -PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSN 296
Query: 303 GDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFP 362
GDP SPDSLHY+SP GVNEYL ALWSVG V+QDYD+DK+FPAFGFGAQ+PP WQVSHEF
Sbjct: 297 GDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFA 356
Query: 363 MNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFV 422
+NFNPSNPYC GIQGIV+AYR LPQ++LYGPTNF+PIINHVARFAA A Q TASQYF+
Sbjct: 357 LNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQYFM 416
Query: 423 LLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVA 482
LL++TDG +TD++ TR+A+V AS LPMS+IIVGVGGADF AME LD DGG L + G+ A
Sbjct: 417 LLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAA 476
Query: 483 IRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNT-----YKLLPP--KNPATKQQ 535
RDIVQFVP+R+FQNAP+EALAQ VLAE+P Q+V YF K LPP K+PA Q
Sbjct: 477 ARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQ 536
>gi|197333761 copine I isoform b [Homo sapiens]
Length = 542
Score = 746 bits (1926), Expect = 0.0
Identities = 356/540 (65%), Positives = 432/540 (80%), Gaps = 12/540 (2%)
Query: 3 AQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKT 62
A CVT V L++SC +L+DKDIGSKSDPLCVL + G W E+ RTER++NC +P+FSKT
Sbjct: 7 AHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSPEFSKT 66
Query: 63 FIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRP 122
++Y FE VQKL+FG+YDIDNKT EL DDDFLG EC+LGQIVSS+ LT PL++K G+P
Sbjct: 67 LQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQVLTLPLMLKPGKP 126
Query: 123 AGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEV 182
AG+G+IT+SA+E+KDNRVV E+EAR LD KD GKSDP+LEF +Q DG W +V+R+EV
Sbjct: 127 AGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQ-GDGKWHLVYRSEV 185
Query: 183 VKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRS 242
+KNNLNP W+ F + + C G+ I+V+C DYD+DGSHDLIGTF T++ +L+
Sbjct: 186 IKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHDLIGTFHTSLAQLQAV--- 242
Query: 243 SPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSN 302
P EFECI+ +K+QKKKSYKNSG I VK C + E +FLDY+MGGCQ+NFTVGVDFTGSN
Sbjct: 243 -PAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVMGGCQINFTVGVDFTGSN 301
Query: 303 GDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFP 362
GDP SPDSLHY+SP GVNEYL ALWSVG V+QDYD+DK+FPAFGFGAQ+PP WQVSHEF
Sbjct: 302 GDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFA 361
Query: 363 MNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFV 422
+NFNPSNPYC GIQGIV+AYR LPQ++LYGPTNF+PIINHVARFAA A Q TASQYF+
Sbjct: 362 LNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAHQGTASQYFM 421
Query: 423 LLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVA 482
LL++TDG +TD++ TR+A+V AS LPMS+IIVGVGGADF AME LD DGG L + G+ A
Sbjct: 422 LLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAMEQLDADGGPLHTRSGQAA 481
Query: 483 IRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNT-----YKLLPP--KNPATKQQ 535
RDIVQFVP+R+FQNAP+EALAQ VLAE+P Q+V YF K LPP K+PA Q
Sbjct: 482 ARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPLKPLPPSAKDPAQAPQ 541
>gi|30181236 copine II [Homo sapiens]
Length = 548
Score = 724 bits (1870), Expect = 0.0
Identities = 340/525 (64%), Positives = 425/525 (80%), Gaps = 2/525 (0%)
Query: 5 CVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFI 64
CV KV L+VS NLLD+D+ SKSDP CVLF +G+ W E +RTE N LNP FSK F+
Sbjct: 22 CVCKVELSVSGQNLLDRDVTSKSDPFCVLFTENNGR-WIEYDRTETAINNLNPAFSKKFV 80
Query: 65 IDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAG 124
+DY+FE VQKLKF ++D D ++ L + DFLG+ C+LG IVSSKK+TRPL++ +PAG
Sbjct: 81 LDYHFEEVQKLKFALFDQDKSSMRLDEHDFLGQFSCSLGTIVSSKKITRPLLLLNDKPAG 140
Query: 125 KGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVK 184
KG ITI+A+E+ DNRV+ + R+LD KDLFGKSDP+LEF+K DG W++VHRTEV+K
Sbjct: 141 KGLITIAAQELSDNRVITLSLAGRRLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIK 200
Query: 185 NNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSP 244
L+PVW+PF + L SLC GDM+K I+V CYDYDNDG HD IG FQT+++++ EA S P
Sbjct: 201 YTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGHDFIGEFQTSVSQMCEARDSVP 260
Query: 245 VEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGD 304
+EFECIN KK++KKK+YKNSG+I ++ C+I + +FLDYI+GGCQL FTVG+DFT SNG+
Sbjct: 261 LEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYILGGCQLMFTVGIDFTASNGN 320
Query: 305 PRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMN 364
P P SLHYI+P G NEYL+A+W+VG +IQDYD+DKMFPA GFGAQ+PP W+VSHEF +N
Sbjct: 321 PLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAIN 380
Query: 365 FNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFVLL 424
FNP+NP+C+G+ GI +AY +CLP I+ YGPTNFSPI+NHVARFAA ATQQ+TA+QYF+LL
Sbjct: 381 FNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQRTATQYFILL 440
Query: 425 IITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVAIR 484
IITDGVI+D++ETR A+V AS+LPMSIIIVGVG ADF+AMEFLDGD LRS GE A R
Sbjct: 441 IITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAAR 500
Query: 485 DIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKN 529
DIVQFVPFR+F+NA KE LA+ VLAE+PQQVV YF +K LPP N
Sbjct: 501 DIVQFVPFREFRNAAKETLAKAVLAELPQQVVQYFK-HKNLPPTN 544
>gi|18677733 copine IV [Homo sapiens]
Length = 557
Score = 603 bits (1555), Expect = e-172
Identities = 297/523 (56%), Positives = 383/523 (73%), Gaps = 3/523 (0%)
Query: 5 CVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFI 64
C+TKV L V+C + D+D SK DP +L + + GQ W+EV+RTE I+ C+NP +SK F
Sbjct: 22 CLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQ-WFEVDRTEVIRTCINPVYSKLFT 80
Query: 65 IDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAG 124
+D+YFE VQ+L+F V+DI + L + DFLG ECTLGQIVS +KL++ L +K G AG
Sbjct: 81 VDFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQRKLSKSL-LKHGNTAG 139
Query: 125 KGSITISAEEIKDNR-VVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVV 183
K SIT+ AEE+ N V ARKLD+KD F KSDP+LE + D +VHRTEVV
Sbjct: 140 KSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVV 199
Query: 184 KNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSS 243
NNL+P W+ FK+S+NSLC GD D+ +K +D+D++G HD IG F +T +++ A
Sbjct: 200 MNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGK 259
Query: 244 PVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSNG 303
V++ECIN K + KKK+YKNSG + + C+I +FLDYIMGGCQ+ FTV +DFT SNG
Sbjct: 260 QVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNG 319
Query: 304 DPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPM 363
DPR+ SLHYI P NEYL AL +VG + QDYD+DKMFPAFGFGA+IPP++ VSH+F +
Sbjct: 320 DPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAI 379
Query: 364 NFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFVL 423
NFN NP C GIQG+VEAY+SCLP+++LYGPTN +PII VA+ A+ T + ASQYF+L
Sbjct: 380 NFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFIL 439
Query: 424 LIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVAI 483
LI+TDGVITD+ +TR+AIV+AS LPMS+IIVGVG ADFS M+ LDGD G LRSP GE +
Sbjct: 440 LILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVL 499
Query: 484 RDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLP 526
RDIVQFVPFR F++A ALA+ VLAE+P QVV Y+N + P
Sbjct: 500 RDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNGKGIKP 542
>gi|25141328 copine 7 isoform a [Homo sapiens]
Length = 558
Score = 601 bits (1549), Expect = e-172
Identities = 298/531 (56%), Positives = 392/531 (73%), Gaps = 4/531 (0%)
Query: 1 MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFS 60
+ A C +KV L +SC +LLD+D +KSDP L GQ W +V RTE +++ L+P FS
Sbjct: 16 LPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQ-WVQVGRTEVVRSSLHPVFS 74
Query: 61 KTFIIDYYFEVVQKLKFGVYDIDNKT-IELSDDDFLGECECTLGQIVSSKKLTRPLVMKT 119
K F +DYYFE VQ+L+F VYD + +DDFLG ECTLGQIV+ KK+TRPL++K
Sbjct: 75 KVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKF 134
Query: 120 GRPAGKGSITISAEEIKDNR-VVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVH 178
GR AGK +IT+ AE+I N V ARKLD+KDLF KSDP+LE ++ D +V+
Sbjct: 135 GRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVY 194
Query: 179 RTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKE 238
RTEVVKNNLNPVW FK+SL+SLC + + +K +DYD+ G HD IG F TT ++++
Sbjct: 195 RTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQK 254
Query: 239 ASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDF 298
A +++C+N K +QK++SYKNSGV+ + + +FLDYIMGGCQ++FTV +DF
Sbjct: 255 AFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDF 314
Query: 299 TGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVS 358
T SNGDPR+ SLHYI+P NEYL AL SVG + QDYD+DK F A GFGA+IPP+++VS
Sbjct: 315 TASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVS 374
Query: 359 HEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTAS 418
H+F +NFNP + C GIQG+VEAY++CLP+++LYGPTN +PII+ VAR AAA AS
Sbjct: 375 HDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKAS 434
Query: 419 QYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPL 478
QY++LLI+TDGV+TD+ +TR+AIV ASRLPMSIIIVGVG ADF+ M+ LDGD G LRSP
Sbjct: 435 QYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPR 494
Query: 479 GEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKN 529
GE A+RDIVQFVPFR+ +NA ALA+CVLAE+P+QVV Y+ +++ LPP++
Sbjct: 495 GEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYY-SHRGLPPRS 544
>gi|5174421 copine 6 [Homo sapiens]
Length = 557
Score = 571 bits (1471), Expect = e-163
Identities = 286/523 (54%), Positives = 370/523 (70%), Gaps = 4/523 (0%)
Query: 7 TKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIID 66
++V L VSC LLD+D +K P CVL S +QW EVERTE +++C +P FS+ ++
Sbjct: 20 SRVELRVSCHGLLDRDTLTKPHP-CVLLKLYSDEQWVEVERTEVLRSCSSPVFSRVLALE 78
Query: 67 YYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGKG 126
Y+FE Q L+F V+D ++ +D FLG ECTLGQIVS K+T+PL++K G+ AGK
Sbjct: 79 YFFEEKQPLQFHVFDAEDGATSPRNDTFLGSTECTLGQIVSQTKVTKPLLLKNGKTAGKS 138
Query: 127 SITISAEEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKN 185
+ITI AEE+ N V A KLDNKDLF KSDP++E +K D + +V RTEVVKN
Sbjct: 139 TITIVAEEVSGTNDYVQLTFRAYKLDNKDLFSKSDPFMEIYKTNEDQSDQLVWRTEVVKN 198
Query: 186 NLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKE--ASRSS 243
NLNP W PF++SL+SLC D+ + +K YDYD+ G HD IG F +T +++E A+
Sbjct: 199 NLNPSWEPFRLSLHSLCSCDVHRPLKFLVYDYDSSGKHDFIGEFTSTFQEMQEGTANPGQ 258
Query: 244 PVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSNG 303
++++CIN K R KKK+YK+SG + + QC + TFLDYIMGGCQ++FTV +DFT SNG
Sbjct: 259 EMQWDCINPKYRDKKKNYKSSGTVVLAQCTVEKVHTFLDYIMGGCQISFTVAIDFTASNG 318
Query: 304 DPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPM 363
DPRS SLH +SP N YL AL +VG + QDYD+DK FPAFGFGA+IPP ++VSH+F +
Sbjct: 319 DPRSSQSLHCLSPRQPNHYLQALRAVGGICQDYDSDKRFPAFGFGARIPPNFEVSHDFAI 378
Query: 364 NFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFVL 423
NF+P NP C I G++ +YR CLPQI+LYGPTN +PIIN VA A A++Y VL
Sbjct: 379 NFDPENPECEEISGVIASYRRCLPQIQLYGPTNVAPIINRVAEPAQREQSTGQATKYSVL 438
Query: 424 LIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVAI 483
L++TDGV++D+ ETR AIV ASRLPMSIIIVGVG ADFS M LDGD G LR P G A
Sbjct: 439 LVLTDGVVSDMAETRTAIVRASRLPMSIIIVGVGNADFSDMRLLDGDDGPLRCPRGVPAA 498
Query: 484 RDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLP 526
RDIVQFVPFR F++A ALA+CVLAE+P+QVV Y+ + + P
Sbjct: 499 RDIVQFVPFRDFKDAAPSALAKCVLAEVPRQVVEYYASQGISP 541
>gi|25121972 copine VIII [Homo sapiens]
Length = 564
Score = 543 bits (1399), Expect = e-154
Identities = 281/539 (52%), Positives = 377/539 (69%), Gaps = 17/539 (3%)
Query: 2 AAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSG-QQWYEVERTERIKNCLNPQFS 60
AA T+V ++VSC NLLD+D SKSDP+CVL++ G ++W E RTE I N LNP F
Sbjct: 19 AAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFV 78
Query: 61 KTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSK--KLTRPLVMK 118
+ FI+DY+FE + L+F +YD+D+K+ LS DFLG+ CTLG+IV S+ +L +P+V
Sbjct: 79 RKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGI 138
Query: 119 TGRPAGKGSITISAEEIKDNR-VVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMV 177
G+ G +I ++AEE+ R VL + A KLD KD FGKSDP+L F++ DG++ +
Sbjct: 139 PGKKCG--TIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTIC 196
Query: 178 HRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLK 237
H+TEVVKN LNPVW+ FKIS+ +LC GD D+TIKVE YD+D DGSHD IG F T+ +L
Sbjct: 197 HKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELS 256
Query: 238 EASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVD 297
V +E +N KK+ KKK Y NSG +++ + E +FLDYI GG Q+NFTV +D
Sbjct: 257 RGQSQFNV-YEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAID 315
Query: 298 FTGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQV 357
FT SNG+P P SLHY++P +N Y AL +VG ++QDYD+DKMFPA GFGA++PP ++
Sbjct: 316 FTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRI 375
Query: 358 SHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTA 417
SHEF +N NP NPYC+GI+G++EAY L ++LYGPTNF+P+INHVAR+A++ +
Sbjct: 376 SHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSV---KDG 432
Query: 418 SQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSP 477
SQYFVLLI+TDGVI+D+ +T+++IVNAS+LPMSIIIVGVG A+F AM LDGD + S
Sbjct: 433 SQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRV-SS 491
Query: 478 LGEVAIRDIVQFVPFRQFQN------APKEALAQCVLAEIPQQVVGYFNTYKLLPPKNP 530
G+ A RDIVQFVPFR + + LA+ VLAEIP+Q + Y + P P
Sbjct: 492 RGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAP 550
>gi|25141323 copine V [Homo sapiens]
Length = 593
Score = 538 bits (1385), Expect = e-153
Identities = 288/553 (52%), Positives = 370/553 (66%), Gaps = 33/553 (5%)
Query: 7 TKVALNVSCANLLDKDIGSKSDPLCVLFLN-TSGQQWYEVERTERIKNCLNPQFSKTFII 65
TKV + VSC NLLDKD+ SKSDPLCV++ +QW E RTE I N LNP F + FI+
Sbjct: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
Query: 66 DYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSS--KKLTRPLVM------ 117
DY+FE Q L+F +YD+D+K+ +LS DFLG+ CTLG+IV S +L +PL +
Sbjct: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
Query: 118 -KTGRPA---------GK--GSITISAEEIKDNR-VVLFEMEARKLDNKDLFGKSDPYLE 164
+TG+P GK G+I +SAEE+ + R V + A KLD KD FGKSDP+L
Sbjct: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
Query: 165 FHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHD 224
F++ DG + + H+TEV+KN LNPVW+ F I + +LC GD D+TIKVE YD+D DGSHD
Sbjct: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
Query: 225 LIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYI 284
IG F T+ +L + +E +N KK+ KKK Y NSG +++ + ECTFLDYI
Sbjct: 263 FIGEFTTSYRELARGQSQFNI-YEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYI 321
Query: 285 MGGCQLNFTVGVDFTGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPA 344
GG Q+NFTV +DFT SNG+P SLHY+SP +N Y AL +VG +IQ YD+DKMFPA
Sbjct: 322 KGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPA 381
Query: 345 FGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHV 404
GFGA++PP +VSHEFP+N N NP C GI GI+EAY L ++LYGPTNF+P++ HV
Sbjct: 382 LGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHV 441
Query: 405 ARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAM 464
AR AAA Q SQY VLLIITDGVI+D+ +T++AIVNA++LPMSIIIVGVG A+F AM
Sbjct: 442 ARNAAAV---QDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAM 498
Query: 465 EFLDGDGGSLRSPLGEVAIRDIVQFVPFRQFQN------APKEALAQCVLAEIPQQVVGY 518
LDGD + S G++A RDIVQFVPFR + + LA+ VLAEIP Q+V Y
Sbjct: 499 VELDGDDVRI-SSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSY 557
Query: 519 FNTYKLLPPKNPA 531
+ P PA
Sbjct: 558 MKAQGIRPRPPPA 570
>gi|88703066 copine-like protein [Homo sapiens]
Length = 553
Score = 511 bits (1317), Expect = e-145
Identities = 269/540 (49%), Positives = 367/540 (67%), Gaps = 23/540 (4%)
Query: 7 TKVALNVSCANLLDKDIGSKSDPLCVLFLNT-SGQQWYEVERTERIKNCLNPQFSKTFII 65
TK+ + VSC NLLD D SKSDP+ VL+ + + Q+W E RTE I N LNP F + F++
Sbjct: 14 TKIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRKFVL 73
Query: 66 DYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSK--KLTRPLVMKTGRPA 123
DY+FE Q L+F VY++D+KT DFLG+ LG+++ + ++ R L TG P
Sbjct: 74 DYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGSRVERTL---TGVPG 130
Query: 124 GK-GSITISAEEIKDNR-VVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTE 181
K G+I ++AEE+ + R + ++ A KLD KD FGKSDP+L F++ DG + + H+TE
Sbjct: 131 KKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTE 190
Query: 182 VVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASR 241
VVKN LNPVW+PF I + +LC GD D+T+K++ YD+D DGSHD IG F T+ +L +A
Sbjct: 191 VVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQN 250
Query: 242 SSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGS 301
V +E +N +K+ KKK Y NSG +++ + E TF+DYI GG QLNFTV +DFT S
Sbjct: 251 QFTV-YEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTAS 309
Query: 302 NGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEF 361
NG+P P SLHY+SP ++ Y AL +VG +IQDYD+DK+FPA+GFGA++PP+ ++SH+F
Sbjct: 310 NGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQF 369
Query: 362 PMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYF 421
P+N N +P C GI+G++E+Y L ++LYGPT F+P+IN VAR AA + SQY+
Sbjct: 370 PLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVAR---AAAKISDGSQYY 426
Query: 422 VLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEV 481
VLLIITDGVI+D+ +T++AIV+AS LPMSIIIVGVG A F AME LDGD + S G
Sbjct: 427 VLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRV-SSRGRY 485
Query: 482 AIRDIVQFVPFRQF------QNAPKEALAQCVLAEIPQQVVGYFNTYKLL----PPKNPA 531
A RDIVQFVPFR + Q LA+ VLAEIP+Q++ Y T + PP NP+
Sbjct: 486 AERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQPRPPPPANPS 545
>gi|7656993 copine 7 isoform b [Homo sapiens]
Length = 633
Score = 505 bits (1301), Expect = e-143
Identities = 247/427 (57%), Positives = 325/427 (76%), Gaps = 2/427 (0%)
Query: 104 QIVSSKKLTRPLVMKTGRPAGKGSITISAEEIKDNR-VVLFEMEARKLDNKDLFGKSDPY 162
QIV+ KK+TRPL++K GR AGK +IT+ AE+I N V ARKLD+KDLF KSDP+
Sbjct: 194 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF 253
Query: 163 LEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGS 222
LE ++ D +V+RTEVVKNNLNPVW FK+SL+SLC + + +K +DYD+ G
Sbjct: 254 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK 313
Query: 223 HDLIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLD 282
HD IG F TT ++++A +++C+N K +QK++SYKNSGV+ + + +FLD
Sbjct: 314 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD 373
Query: 283 YIMGGCQLNFTVGVDFTGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMF 342
YIMGGCQ++FTV +DFT SNGDPR+ SLHYI+P NEYL AL SVG + QDYD+DK F
Sbjct: 374 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF 433
Query: 343 PAFGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIIN 402
A GFGA+IPP+++VSH+F +NFNP + C GIQG+VEAY++CLP+++LYGPTN +PII+
Sbjct: 434 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS 493
Query: 403 HVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFS 462
VAR AAA ASQY++LLI+TDGV+TD+ +TR+AIV ASRLPMSIIIVGVG ADF+
Sbjct: 494 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT 553
Query: 463 AMEFLDGDGGSLRSPLGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTY 522
M+ LDGD G LRSP GE A+RDIVQFVPFR+ +NA ALA+CVLAE+P+QVV Y+ ++
Sbjct: 554 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYY-SH 612
Query: 523 KLLPPKN 529
+ LPP++
Sbjct: 613 RGLPPRS 619
Score = 102 bits (253), Expect = 1e-21
Identities = 52/105 (49%), Positives = 68/105 (64%), Gaps = 2/105 (1%)
Query: 1 MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFS 60
+ A C +KV L +SC +LLD+D +KSDP L GQ W +V RTE +++ L+P FS
Sbjct: 16 LPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQ-WVQVGRTEVVRSSLHPVFS 74
Query: 61 KTFIIDYYFEVVQKLKFGVYDIDNKT-IELSDDDFLGECECTLGQ 104
K F +DYYFE VQ+L+F VYD + +DDFLG ECTLGQ
Sbjct: 75 KVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ 119
Score = 42.0 bits (97), Expect = 0.001
Identities = 34/100 (34%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 9 VALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNP---QFSKTFII 65
V L+ L DKD+ SKSDP L+ Q V RTE +KN LNP F +
Sbjct: 232 VELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSS 291
Query: 66 DYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQI 105
E + LK V+D D++ DF+GE T ++
Sbjct: 292 LCSCEETRPLKCLVWDYDSR----GKHDFIGEFSTTFEEM 327
Score = 38.5 bits (88), Expect = 0.016
Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 6/77 (7%)
Query: 141 VLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVW-RPFKISLN 199
V + R L ++D KSDP + +Q + G W+ V RTEVV+++L+PV+ + F +
Sbjct: 24 VELRLSCRHLLDRDPLTKSDPSVALLQQ-AQGQWVQVGRTEVVRSSLHPVFSKVFTVDY- 81
Query: 200 SLCYGDMDKTIKVECYD 216
Y + + ++ E YD
Sbjct: 82 ---YFEEVQRLRFEVYD 95
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 62.8 bits (151), Expect = 8e-10
Identities = 58/224 (25%), Positives = 97/224 (43%), Gaps = 21/224 (9%)
Query: 13 VSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVV 72
+ A L D+G SDP +FL ++ YE T+ + LNP F++TF ++ +
Sbjct: 161 LQAAELPALDMGGTSDPYVKVFLLPDKKKKYE---TKVHRKTLNPAFNETFTFKVPYQEL 217
Query: 73 --QKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGR---PAGKGS 127
+ L +YD D S D +GE + + + + + ++ G P G
Sbjct: 218 GGKTLVMAIYDFDR----FSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGD 273
Query: 128 ITISAEEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNN 186
I S + ++ + +EA+ L D+ G SDPY++ H +G L +T V K
Sbjct: 274 ICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLM-QNGKRLKKKKTTVKKKT 332
Query: 187 LNPVWR---PFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG 227
LNP + F+I + + V DYD G ++ IG
Sbjct: 333 LNPYFNESFSFEIPFEQI----QKVQVVVTVLDYDKLGKNEAIG 372
Score = 40.8 bits (94), Expect = 0.003
Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 11/116 (9%)
Query: 122 PAGKGSITISAE-EIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRT 180
P G + S + + + N++ + ++A +L D+ G SDPY++ + T
Sbjct: 137 PENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKK---KYET 193
Query: 181 EVVKNNLNPVWRP---FKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTM 233
+V + LNP + FK+ L KT+ + YD+D HD+IG + M
Sbjct: 194 KVHRKTLNPAFNETFTFKVPYQELG----GKTLVMAIYDFDRFSKHDIIGEVKVPM 245
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 62.8 bits (151), Expect = 8e-10
Identities = 58/224 (25%), Positives = 97/224 (43%), Gaps = 21/224 (9%)
Query: 13 VSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVV 72
+ A L D+G SDP +FL ++ YE T+ + LNP F++TF ++ +
Sbjct: 161 LQAAELPALDMGGTSDPYVKVFLLPDKKKKYE---TKVHRKTLNPAFNETFTFKVPYQEL 217
Query: 73 --QKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGR---PAGKGS 127
+ L +YD D S D +GE + + + + + ++ G P G
Sbjct: 218 GGKTLVMAIYDFDR----FSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGD 273
Query: 128 ITISAEEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNN 186
I S + ++ + +EA+ L D+ G SDPY++ H +G L +T V K
Sbjct: 274 ICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLM-QNGKRLKKKKTTVKKKT 332
Query: 187 LNPVWR---PFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG 227
LNP + F+I + + V DYD G ++ IG
Sbjct: 333 LNPYFNESFSFEIPFEQI----QKVQVVVTVLDYDKLGKNEAIG 372
Score = 40.8 bits (94), Expect = 0.003
Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 11/116 (9%)
Query: 122 PAGKGSITISAE-EIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRT 180
P G + S + + + N++ + ++A +L D+ G SDPY++ + T
Sbjct: 137 PENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKK---KYET 193
Query: 181 EVVKNNLNPVWRP---FKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTM 233
+V + LNP + FK+ L KT+ + YD+D HD+IG + M
Sbjct: 194 KVHRKTLNPAFNETFTFKVPYQELG----GKTLVMAIYDFDRFSKHDIIGEVKVPM 245
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 60.1 bits (144), Expect = 5e-09
Identities = 60/216 (27%), Positives = 92/216 (42%), Gaps = 23/216 (10%)
Query: 22 DIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDY-YFEVVQK-LKFGV 79
D+G SDP ++L ++ YE T+ + LNP F +TF Y E+ + L V
Sbjct: 139 DLGGSSDPYVRVYLLPDKRRRYE---TKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAV 195
Query: 80 YDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGK-------GSITISA 132
YD D S +D +GE + SS L RP+ A G I S
Sbjct: 196 YDFDR----FSRNDAIGEVRVPM----SSVDLGRPVQAWRELQAAPREEQEKLGDICFSL 247
Query: 133 EEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVW 191
+ ++ + +EA+ L D+ G SDPY++ H G + +T + KN LNP +
Sbjct: 248 RYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVH-LLQGGKKVRKKKTTIKKNTLNPYY 306
Query: 192 RPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG 227
S C +++ DYD G ++ IG
Sbjct: 307 NE-AFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIG 341
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 58.5 bits (140), Expect = 1e-08
Identities = 57/224 (25%), Positives = 95/224 (42%), Gaps = 21/224 (9%)
Query: 13 VSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSK--TFIIDYYFE 70
+ A L D+G SDP +FL ++ +E T+ + LNP F++ TF + Y
Sbjct: 164 IQAAELPALDMGGTSDPYVKVFLLPDKKKKFE---TKVHRKTLNPVFNEQFTFKVPYSEL 220
Query: 71 VVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGK---GS 127
+ L VYD D S D +GE + + + +++ + G
Sbjct: 221 GGKTLVMAVYDFDR----FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGD 276
Query: 128 ITISAEEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNN 186
I S + ++ + +EA+ L D+ G SDPY++ H +G L +T + KN
Sbjct: 277 ICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLM-QNGKRLKKKKTTIKKNT 335
Query: 187 LNPVWR---PFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG 227
LNP + F++ + + V DYD G +D IG
Sbjct: 336 LNPYYNESFSFEVPFEQI----QKVQVVVTVLDYDKIGKNDAIG 375
Score = 43.9 bits (102), Expect = 4e-04
Identities = 34/132 (25%), Positives = 63/132 (47%), Gaps = 19/132 (14%)
Query: 134 EIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRP 193
+ ++N++++ ++A +L D+ G SDPY++ T+V + LNPV+
Sbjct: 153 DFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKF---ETKVHRKTLNPVFNE 209
Query: 194 ---FKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEFECI 250
FK+ + L KT+ + YD+D HD+IG F+ M + V+F +
Sbjct: 210 QFTFKVPYSELG----GKTLVMAVYDFDRFSKHDIIGEFKVPM---------NTVDFGHV 256
Query: 251 NEKKRQKKKSYK 262
E+ R + + K
Sbjct: 257 TEEWRDLQSAEK 268
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 58.5 bits (140), Expect = 1e-08
Identities = 57/224 (25%), Positives = 95/224 (42%), Gaps = 21/224 (9%)
Query: 13 VSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSK--TFIIDYYFE 70
+ A L D+G SDP +FL ++ +E T+ + LNP F++ TF + Y
Sbjct: 164 IQAAELPALDMGGTSDPYVKVFLLPDKKKKFE---TKVHRKTLNPVFNEQFTFKVPYSEL 220
Query: 71 VVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGK---GS 127
+ L VYD D S D +GE + + + +++ + G
Sbjct: 221 GGKTLVMAVYDFDR----FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGD 276
Query: 128 ITISAEEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNN 186
I S + ++ + +EA+ L D+ G SDPY++ H +G L +T + KN
Sbjct: 277 ICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLM-QNGKRLKKKKTTIKKNT 335
Query: 187 LNPVWR---PFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG 227
LNP + F++ + + V DYD G +D IG
Sbjct: 336 LNPYYNESFSFEVPFEQI----QKVQVVVTVLDYDKIGKNDAIG 375
Score = 43.9 bits (102), Expect = 4e-04
Identities = 34/132 (25%), Positives = 63/132 (47%), Gaps = 19/132 (14%)
Query: 134 EIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRP 193
+ ++N++++ ++A +L D+ G SDPY++ T+V + LNPV+
Sbjct: 153 DFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKF---ETKVHRKTLNPVFNE 209
Query: 194 ---FKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEFECI 250
FK+ + L KT+ + YD+D HD+IG F+ M + V+F +
Sbjct: 210 QFTFKVPYSELG----GKTLVMAVYDFDRFSKHDIIGEFKVPM---------NTVDFGHV 256
Query: 251 NEKKRQKKKSYK 262
E+ R + + K
Sbjct: 257 TEEWRDLQSAEK 268
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 58.5 bits (140), Expect = 1e-08
Identities = 57/224 (25%), Positives = 95/224 (42%), Gaps = 21/224 (9%)
Query: 13 VSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSK--TFIIDYYFE 70
+ A L D+G SDP +FL ++ +E T+ + LNP F++ TF + Y
Sbjct: 164 IQAAELPALDMGGTSDPYVKVFLLPDKKKKFE---TKVHRKTLNPVFNEQFTFKVPYSEL 220
Query: 71 VVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGK---GS 127
+ L VYD D S D +GE + + + +++ + G
Sbjct: 221 GGKTLVMAVYDFDR----FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGD 276
Query: 128 ITISAEEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNN 186
I S + ++ + +EA+ L D+ G SDPY++ H +G L +T + KN
Sbjct: 277 ICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLM-QNGKRLKKKKTTIKKNT 335
Query: 187 LNPVWR---PFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG 227
LNP + F++ + + V DYD G +D IG
Sbjct: 336 LNPYYNESFSFEVPFEQI----QKVQVVVTVLDYDKIGKNDAIG 375
Score = 43.9 bits (102), Expect = 4e-04
Identities = 34/132 (25%), Positives = 63/132 (47%), Gaps = 19/132 (14%)
Query: 134 EIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRP 193
+ ++N++++ ++A +L D+ G SDPY++ T+V + LNPV+
Sbjct: 153 DFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKF---ETKVHRKTLNPVFNE 209
Query: 194 ---FKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEFECI 250
FK+ + L KT+ + YD+D HD+IG F+ M + V+F +
Sbjct: 210 QFTFKVPYSELG----GKTLVMAVYDFDRFSKHDIIGEFKVPM---------NTVDFGHV 256
Query: 251 NEKKRQKKKSYK 262
E+ R + + K
Sbjct: 257 TEEWRDLQSAEK 268
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 58.5 bits (140), Expect = 1e-08
Identities = 59/229 (25%), Positives = 100/229 (43%), Gaps = 22/229 (9%)
Query: 13 VSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVV 72
+ +L KD SDP ++L ++ ++ T + LNP F +TF ++ +
Sbjct: 253 IKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQ---TRVHRKTLNPLFDETFQFPVAYDQL 309
Query: 73 --QKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVM------KTGRPAG 124
+KL F VYD D S D +GE L + L+R + T
Sbjct: 310 SNRKLHFSVYDFDR----FSRHDMIGEV--ILDNLFEVSDLSREATVWKDIHCATTESID 363
Query: 125 KGSITISAEEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVV 183
G I S + R+ L ++ R L D+ G SDPY++ +G L +T
Sbjct: 364 LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMC-EGRRLKKRKTTTK 422
Query: 184 KNNLNPVWRPFKISLNSLCYGDMDK-TIKVECYDYDNDGSHDLIGTFQT 231
KN LNPV+ + + + ++D+ ++ + DYD G +++IG +T
Sbjct: 423 KNTLNPVYN--EAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRT 469
Score = 35.8 bits (81), Expect = 0.10
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
Query: 13 VSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVV 72
+ C NL DI SDP + L G++ + +T KN LNP +++ I D E V
Sbjct: 385 IKCRNLKAMDITGSSDPYVKVSLMCEGRR-LKKRKTTTKKNTLNPVYNEAIIFDIPPENV 443
Query: 73 QKLKFGVYDIDNKTIELSDDDFLGECECTL 102
++ + +D + ++ +G C L
Sbjct: 444 DQVSLSIAVMDYDRV--GHNEVIGVCRTGL 471
Score = 33.9 bits (76), Expect = 0.39
Identities = 28/125 (22%), Positives = 58/125 (46%), Gaps = 12/125 (9%)
Query: 126 GSITISAEEIKDNRVVLFEM-EARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVK 184
G + + + +N +++ ++ +A L KD G SDPY++ + +T V +
Sbjct: 233 GKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKK---KFQTRVHR 289
Query: 185 NNLNPVWR---PFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG-TFQTTMTKLKEAS 240
LNP++ F ++ + L ++ + YD+D HD+IG + ++ + S
Sbjct: 290 KTLNPLFDETFQFPVAYDQL----SNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLS 345
Query: 241 RSSPV 245
R + V
Sbjct: 346 REATV 350
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 55.8 bits (133), Expect = 9e-08
Identities = 57/222 (25%), Positives = 95/222 (42%), Gaps = 18/222 (8%)
Query: 17 NLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFI--IDYYFEVVQK 74
NL KD SDP ++L + ++ T+ + LNP F + F+ + Y +K
Sbjct: 246 NLPAKDFSGTSDPYVKIYLLPDRKTKHQ---TKVHRKTLNPVFDEVFLFPVPYNDLEARK 302
Query: 75 LKFGVYDIDNKTIELSDDDFLGECECT----LGQIVSSKKLTRPLVMKTGRPAGKGSITI 130
L F VYD D S D +G+ L L + + T G +
Sbjct: 303 LHFSVYDFDR----FSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMF 358
Query: 131 SAEEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNP 189
S + R+ + ++AR L D+ G SDPY++ DG L +T +N LNP
Sbjct: 359 SLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMC-DGRRLKKRKTSTKRNTLNP 417
Query: 190 VWRPFKISLNSLCYGDMDKT-IKVECYDYDNDGSHDLIGTFQ 230
V+ + + + ++D+ + + DYD G +++IG Q
Sbjct: 418 VYN--EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQ 457
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 146 EARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGD 205
+A L KD G SDPY++ + H+T+V + LNPV+ ++ L + Y D
Sbjct: 243 KAVNLPAKDFSGTSDPYVKIYLLPDRKT---KHQTKVHRKTLNPVFD--EVFLFPVPYND 297
Query: 206 MD-KTIKVECYDYDNDGSHDLIG 227
++ + + YD+D HDLIG
Sbjct: 298 LEARKLHFSVYDFDRFSRHDLIG 320
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 55.1 bits (131), Expect = 2e-07
Identities = 59/217 (27%), Positives = 96/217 (44%), Gaps = 22/217 (10%)
Query: 21 KDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYF-EVVQ-KLKFG 78
KD SDP ++L ++ ++ T+ + LNP F++TF E+ Q KL F
Sbjct: 329 KDSNGFSDPYVKIYLLPDRKKKFQ---TKVHRKTLNPVFNETFQFSVPLAELAQRKLHFS 385
Query: 79 VYDIDNKTIELSDDDFLGECECT----LGQIVSSKKLTRPLVMKTGRPAGKGSITISAEE 134
VYD D S D +G+ L + + L R +V A G + S
Sbjct: 386 VYDFDR----FSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCY 441
Query: 135 IKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRP 193
+ R+ + ++A L DL G SDPY++ S+G L +T + KN LNP +
Sbjct: 442 LPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA-SLISEGRRLKKRKTSIKKNTLNPTYNE 500
Query: 194 ---FKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG 227
F ++ S+ + + + DYD G +++IG
Sbjct: 501 ALVFDVAPESV----ENVGLSIAVVDYDCIGHNEVIG 533
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 55.1 bits (131), Expect = 2e-07
Identities = 59/217 (27%), Positives = 96/217 (44%), Gaps = 22/217 (10%)
Query: 21 KDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYF-EVVQ-KLKFG 78
KD SDP ++L ++ ++ T+ + LNP F++TF E+ Q KL F
Sbjct: 329 KDSNGFSDPYVKIYLLPDRKKKFQ---TKVHRKTLNPVFNETFQFSVPLAELAQRKLHFS 385
Query: 79 VYDIDNKTIELSDDDFLGECECT----LGQIVSSKKLTRPLVMKTGRPAGKGSITISAEE 134
VYD D S D +G+ L + + L R +V A G + S
Sbjct: 386 VYDFDR----FSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCY 441
Query: 135 IKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRP 193
+ R+ + ++A L DL G SDPY++ S+G L +T + KN LNP +
Sbjct: 442 LPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA-SLISEGRRLKKRKTSIKKNTLNPTYNE 500
Query: 194 ---FKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG 227
F ++ S+ + + + DYD G +++IG
Sbjct: 501 ALVFDVAPESV----ENVGLSIAVVDYDCIGHNEVIG 533
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 55.1 bits (131), Expect = 2e-07
Identities = 59/217 (27%), Positives = 96/217 (44%), Gaps = 22/217 (10%)
Query: 21 KDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYF-EVVQ-KLKFG 78
KD SDP ++L ++ ++ T+ + LNP F++TF E+ Q KL F
Sbjct: 329 KDSNGFSDPYVKIYLLPDRKKKFQ---TKVHRKTLNPVFNETFQFSVPLAELAQRKLHFS 385
Query: 79 VYDIDNKTIELSDDDFLGECECT----LGQIVSSKKLTRPLVMKTGRPAGKGSITISAEE 134
VYD D S D +G+ L + + L R +V A G + S
Sbjct: 386 VYDFDR----FSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCY 441
Query: 135 IKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRP 193
+ R+ + ++A L DL G SDPY++ S+G L +T + KN LNP +
Sbjct: 442 LPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA-SLISEGRRLKKRKTSIKKNTLNPTYNE 500
Query: 194 ---FKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIG 227
F ++ S+ + + + DYD G +++IG
Sbjct: 501 ALVFDVAPESV----ENVGLSIAVVDYDCIGHNEVIG 533
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 54.7 bits (130), Expect = 2e-07
Identities = 58/224 (25%), Positives = 96/224 (42%), Gaps = 22/224 (9%)
Query: 21 KDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVV--QKLKFG 78
KD SDP ++L + + T + LNP F + F +E + +KL
Sbjct: 174 KDFCGSSDPYVKIYLLPDRKCKLQ---TRVHRKTLNPTFDENFHFPVPYEELADRKLHLS 230
Query: 79 VYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRP------LVMKTGRPAGKGSITISA 132
V+D D S D +GE L + + L+R + T G I S
Sbjct: 231 VFDFDR----FSRHDMIGEV--ILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSL 284
Query: 133 EEIKD-NRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVW 191
+ R+ L ++ R L D+ G SDPY++ DG L +T + KN LNPV+
Sbjct: 285 CYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKV-SLLCDGRRLKKKKTTIKKNTLNPVY 343
Query: 192 RPFKISLNSLCYGDMDK-TIKVECYDYDNDGSHDLIGTFQTTMT 234
+ + + +MD+ ++ + DYD G +++IG + +T
Sbjct: 344 N--EAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGIT 385
Score = 34.7 bits (78), Expect = 0.23
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 12/99 (12%)
Query: 145 MEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRP---FKISLNSL 201
++A L KD G SDPY++ + L +T V + LNP + F + L
Sbjct: 166 LKAFDLPAKDFCGSSDPYVKIYLLPDRKCKL---QTRVHRKTLNPTFDENFHFPVPYEEL 222
Query: 202 CYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEAS 240
D+ + + +D+D HD+IG + + L EAS
Sbjct: 223 A----DRKLHLSVFDFDRFSRHDMIG--EVILDNLFEAS 255
Score = 32.0 bits (71), Expect = 1.5
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 13 VSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVV 72
+ C NL DI SDP + L G++ + ++T KN LNP +++ I D E +
Sbjct: 298 IKCRNLKAMDITGYSDPYVKVSLLCDGRR-LKKKKTTIKKNTLNPVYNEAIIFDIPPENM 356
Query: 73 QK--LKFGVYDIDNKTIELSDDDFLGEC 98
+ L V D D + ++ +G C
Sbjct: 357 DQVSLLISVMDYD----RVGHNEIIGVC 380
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 53.1 bits (126), Expect = 6e-07
Identities = 40/131 (30%), Positives = 65/131 (49%), Gaps = 13/131 (9%)
Query: 146 EARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGD 205
EAR L D G SDPY++ K D L +T VK LNPVW + + +L GD
Sbjct: 179 EARNLIPMDPNGLSDPYVKL-KLIPDPRNLTKQKTRTVKATLNPVWN--ETFVFNLKPGD 235
Query: 206 MDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVE--FECINEKKRQKKKSYKN 263
+++ + VE +D+D +D +G +++L +A PV+ ++ +N Q++ Y N
Sbjct: 236 VERRLSVEVWDWDRTSRNDFMGAMSFGVSELLKA----PVDGWYKLLN----QEEGEYYN 287
Query: 264 SGVISVKQCEI 274
V C +
Sbjct: 288 VPVADADNCSL 298
Score = 30.8 bits (68), Expect = 3.3
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 6/93 (6%)
Query: 17 NLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYY-FEVVQKL 75
NL+ D SDP L L + + ++T +K LNP +++TF+ + +V ++L
Sbjct: 182 NLIPMDPNGLSDPYVKLKLIPDPRNLTK-QKTRTVKATLNPVWNETFVFNLKPGDVERRL 240
Query: 76 KFGVYDIDNKTIELSDDDFLGECECTLGQIVSS 108
V+D D S +DF+G + +++ +
Sbjct: 241 SVEVWDWD----RTSRNDFMGAMSFGVSELLKA 269
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,685,715
Number of Sequences: 37866
Number of extensions: 929981
Number of successful extensions: 2120
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 1787
Number of HSP's gapped (non-prelim): 279
length of query: 537
length of database: 18,247,518
effective HSP length: 107
effective length of query: 430
effective length of database: 14,195,856
effective search space: 6104218080
effective search space used: 6104218080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.