Search of human proteins with 4502027

Search of human proteins with 4502027

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502027 albumin preproprotein [Homo sapiens]
         (609 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502027 albumin preproprotein [Homo sapiens]                      1246   0.0  
gi|4501989 alpha-fetoprotein precursor [Homo sapiens]                 500   e-141
gi|4501987 afamin precursor [Homo sapiens]                            412   e-115
gi|32483410 vitamin D-binding protein precursor [Homo sapiens]        151   1e-36
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     35   0.26 
gi|222446616 hypothetical protein LOC341346 [Homo sapiens]             33   1.00 
gi|239754349 PREDICTED: hypothetical protein [Homo sapiens]            32   1.7  
gi|239748897 PREDICTED: hypothetical protein XP_002346887 [Homo ...    32   1.7  
gi|239742921 PREDICTED: hypothetical protein XP_002342685 [Homo ...    32   1.7  
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap...    32   2.2  
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]           31   3.8  
gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]             31   3.8  
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]    30   6.5  
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]              30   6.5  
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]              30   6.5  
gi|226371655 zinc finger family member 674 isoform 2 [Homo sapiens]    30   8.4  
gi|89994742 zinc finger family member 674 isoform 1 [Homo sapiens]     30   8.4  
gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]             30   8.4  
gi|12232475 IQ motif containing H isoform 2 [Homo sapiens]             30   8.4  
gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens]      30   8.4  

>gi|4502027 albumin preproprotein [Homo sapiens]
          Length = 609

 Score = 1246 bits (3225), Expect = 0.0
 Identities = 609/609 (100%), Positives = 609/609 (100%)

Query: 1   MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60
           MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF
Sbjct: 1   MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60

Query: 61  EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120
           EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP
Sbjct: 61  EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120

Query: 121 ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF 180
           ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF
Sbjct: 121 ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF 180

Query: 181 FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV 240
           FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV
Sbjct: 181 FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV 240

Query: 241 ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLK 300
           ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLK
Sbjct: 241 ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLK 300

Query: 301 ECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYAR 360
           ECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYAR
Sbjct: 301 ECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYAR 360

Query: 361 RHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFE 420
           RHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFE
Sbjct: 361 RHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFE 420

Query: 421 QLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVV 480
           QLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVV
Sbjct: 421 QLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVV 480

Query: 481 LNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTL 540
           LNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTL
Sbjct: 481 LNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTL 540

Query: 541 SEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLV 600
           SEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLV
Sbjct: 541 SEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLV 600

Query: 601 AASQAALGL 609
           AASQAALGL
Sbjct: 601 AASQAALGL 609


>gi|4501989 alpha-fetoprotein precursor [Homo sapiens]
          Length = 609

 Score =  500 bits (1288), Expect = e-141
 Identities = 244/610 (40%), Positives = 363/610 (59%), Gaps = 2/610 (0%)

Query: 1   MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60
           MKWV  I L+FL +   SR + R +   + +   ++   E +   L  I FAQ++Q+  +
Sbjct: 1   MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATY 60

Query: 61  EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120
           ++  K+V +     +    DE +  C ++    F ++LC    + E YG  +DCC++ E 
Sbjct: 61  KEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGH-SDCCSQSEE 119

Query: 121 ERNECFLQHKDDNP-NLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELL 179
            R+ CFL HK   P ++P    PE    C A+ ++ ETF+ K++YEIARRHP+ YAP +L
Sbjct: 120 GRHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTIL 179

Query: 180 FFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWA 239
            +A RY      CC+A +   C   K   +  E + SS   +  CA ++ FG R F+A  
Sbjct: 180 LWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAIT 239

Query: 240 VARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKL 299
           V +LSQ+F K  F E+ KLV D+  VH  CC GD+L+C  D   +  YIC  QD++S+K+
Sbjct: 240 VTKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKI 299

Query: 300 KECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYA 359
            ECC+   LE+  CI   ENDE P  L      F+  +D  +  +  K++FL  F++EY+
Sbjct: 300 TECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYS 359

Query: 360 RRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELF 419
           RRHP  +V ++LR+AK Y+  LEKC    +P EC  K  +E +  ++E Q L K++C LF
Sbjct: 360 RRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLF 419

Query: 420 EQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSV 479
           ++LGEY  QNA LV YTKK PQ+++  L+ ++R +    + CC+  E K + C E    +
Sbjct: 420 QKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADI 479

Query: 480 VLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICT 539
           ++  LC+ HE TPV+  V +CCT S  NRRPCFS+L VDETYVP  F+ + F FH D+C 
Sbjct: 480 IIGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQ 539

Query: 540 LSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKL 599
                 Q  KQ  L+ LVK KP+ T+EQL+AV+ DF+  +EKCC+  ++E CFAEEG+KL
Sbjct: 540 AQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKL 599

Query: 600 VAASQAALGL 609
           ++ ++AALG+
Sbjct: 600 ISKTRAALGV 609


>gi|4501987 afamin precursor [Homo sapiens]
          Length = 599

 Score =  412 bits (1060), Expect = e-115
 Identities = 211/600 (35%), Positives = 327/600 (54%), Gaps = 7/600 (1%)

Query: 1   MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60
           +K   FI  LF  + + +     RD        +F    E+N + + +IAFAQY+Q+  F
Sbjct: 4   LKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFI---EDNIEYITIIAFAQYVQEATF 60

Query: 61  EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120
           E+  KLV ++ E+   C+AD++   C K  + +  +K+C +  L + +   + CC+K + 
Sbjct: 61  EEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHN-FSHCCSKVDA 119

Query: 121 ERNECFLQHKDDNPN-LPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELL 179
           +R  CF  +K  +   LP     + +  C A+  N E+ L  +LYE+ARR+P+ +AP LL
Sbjct: 120 QRRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLL 179

Query: 180 FFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWA 239
             A  ++     CC+  +K  CL  +   +    KA S+ Q+  C +L KFG +      
Sbjct: 180 TVAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIY 239

Query: 240 VARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKL 299
           +A LSQ+FPK EF E+  LV D++  +  CC GD+++C  D + +  +IC  QDSISSK+
Sbjct: 240 IAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKI 299

Query: 300 KECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYA 359
           KECCEK + E+  CI     D+ P DL      F +S++VC+      D F   F +EY+
Sbjct: 300 KECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYS 359

Query: 360 RRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELF 419
           RRHPD S+  LLR+ + Y+  L  CC   +P  CY    D+F    E+   +++Q C+ F
Sbjct: 360 RRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHF 419

Query: 420 EQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSV 479
           + LG+   +   L+R TK  PQ+ST  LV +   +    + CC   E     C ++   +
Sbjct: 420 QNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSE--EFACVDNLADL 477

Query: 480 VLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICT 539
           V  +LC ++E   ++  V  CC  +   RRPCF +L+ D+TYVP  F+ + FTFHAD+C 
Sbjct: 478 VFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQ 537

Query: 540 LSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKL 599
              +E Q K    LV LVK K + T E+L+++  +FA  V+KCCKA+  E CF EE  K+
Sbjct: 538 SQNEELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKI 597


>gi|32483410 vitamin D-binding protein precursor [Homo sapiens]
          Length = 474

 Score =  151 bits (382), Expect = 1e-36
 Identities = 114/468 (24%), Positives = 206/468 (44%), Gaps = 21/468 (4%)

Query: 1   MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60
           MK V  + L   F  A  RG   RD  K++V   F  LG+E+F +L L+ +++      F
Sbjct: 1   MKRVLVLLLAVAFGHALERG---RDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTF 57

Query: 61  EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120
           E   +LV EV    + C A+ +  +C  +  +    K C   +    +   A+CC K+  
Sbjct: 58  EQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGL 117

Query: 121 ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF 180
           ER  C    K      P  V P  D +C AF  + + +  ++++E +  +       L+ 
Sbjct: 118 ERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVS 177

Query: 181 FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV 240
           + K Y +    CC +A    C L +  +L+     ++   R+ C+    +GE+  +   +
Sbjct: 178 YTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRV-CSQYAAYGEKKSRLSNL 236

Query: 241 ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLEC-ADDRADLAKYICENQDSISSKL 299
            +L+Q+ P A+  +V  L  D+T + ++CC     +C A +  +    +C+N  + +SK 
Sbjct: 237 IKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKF 296

Query: 300 KECC-EKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEY 358
           ++CC EK  ++   C   +   ++P +LP +  +   +KDVC          +  + +E 
Sbjct: 297 EDCCQEKTAMDVFVCTYFMPAAQLP-ELPDV--ELPTNKDVCD---PGNTKVMDKYTFEL 350

Query: 359 ARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLV-EEPQNLIKQNCE 417
           +RR      V L ++ +    +L +CC   D   C    F+   PL+ +E  + I +  E
Sbjct: 351 SRR-THLPEVFLSKVLEPTLKSLGECCDVEDSTTC----FNAKGPLLKKELSSFIDKGQE 405

Query: 418 LFEQLGEYKF---QNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCC 462
           L     E  F   +  L  R   K+P  +   L ++        S CC
Sbjct: 406 LCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCC 453



 Score =  103 bits (256), Expect = 6e-22
 Identities = 88/389 (22%), Positives = 164/389 (42%), Gaps = 38/389 (9%)

Query: 224 CASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECC-HGDLLECADDRA 282
           C      G+  F + ++   S++FP   F +VS+LV ++  +   CC  G   +C D R 
Sbjct: 29  CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88

Query: 283 D-LAKYICENQDS--ISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVE--SK 337
             L+   CE+     +     ECC K  LE+  C+A +++   P + P+    +VE  + 
Sbjct: 89  SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQ--PQEFPT----YVEPTND 142

Query: 338 DVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKV 397
           ++C+ + +    +   F++EY+  +    + LL+   K+Y + +  CC +A P  C+ K 
Sbjct: 143 EICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202

Query: 398 FDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKV 457
             + K L      L  + C  +   GE K + + L++  +KVP      ++ ++ ++  +
Sbjct: 203 RLQLKHL-SLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNI 261

Query: 458 GSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNR-------RP 510
            SKCC   E+    C    L     +LC     +  + +   CC E             P
Sbjct: 262 LSKCC---ESASEDCMAKELPEHTVKLC--DNLSTKNSKFEDCCQEKTAMDVFVCTYFMP 316

Query: 511 CFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKA 570
                E+ +  +P          + D+C      + + K T  +    H P+     L  
Sbjct: 317 AAQLPELPDVELPT---------NKDVCD-PGNTKVMDKYTFELSRRTHLPEVF---LSK 363

Query: 571 VMDDFAAFVEKCCKADDKETCFAEEGKKL 599
           V++     + +CC  +D  TCF  +G  L
Sbjct: 364 VLEPTLKSLGECCDVEDSTTCFNAKGPLL 392


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 52/212 (24%), Positives = 83/212 (39%), Gaps = 34/212 (16%)

Query: 400  EFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGS 459
            E K L EE +  + +     +   E +FQ+       K   + S  +L + S    K+  
Sbjct: 1159 ELKMLAEEDKRKVSELTSKLKTTDE-EFQSL------KSSHEKSNKSLEDKSLEFKKLSE 1211

Query: 460  K-------CCKHPEAKRMPCAEDYLSVVLNQL-CVLHEKTPVSDRVTKCCTESLVNRRPC 511
            +       CCK  EA       + +++  ++   +L   +    R TK   E+L+ +   
Sbjct: 1212 ELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKV-KEALLIKTCT 1270

Query: 512  FSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVE-LVKHKPKATKE---Q 567
             S LE     + +E N    +F      L EKE QIK   A +E LV  K    KE   Q
Sbjct: 1271 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQ 1330

Query: 568  LKAVMDDFAAFVEKCCKADDKETCFAEEGKKL 599
             +A              A +KE+C  +  K+L
Sbjct: 1331 QQA--------------ASEKESCITQLKKEL 1348


>gi|222446616 hypothetical protein LOC341346 [Homo sapiens]
          Length = 343

 Score = 32.7 bits (73), Expect = 1.00
 Identities = 18/57 (31%), Positives = 30/57 (52%)

Query: 288 ICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYA 344
           +C+N + +S+KL+    +     SH   E++ +EM A LP   A F+  K   +N A
Sbjct: 221 LCKNVELLSAKLRMYQMEAEDTDSHSSEEIDTEEMEALLPQAPASFLVQKSPPRNTA 277


>gi|239754349 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 105

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 3/49 (6%)

Query: 454 LGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCT 502
           LG + S  C   E  R P A  +    L Q    HE TP S R T+CC+
Sbjct: 49  LGALCSPPCCSNEEPRQPAARPHW---LRQRSKFHEGTPTSARGTRCCS 94


>gi|239748897 PREDICTED: hypothetical protein XP_002346887 [Homo
           sapiens]
          Length = 105

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 3/49 (6%)

Query: 454 LGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCT 502
           LG + S  C   E  R P A  +    L Q    HE TP S R T+CC+
Sbjct: 49  LGALCSPPCCSNEEPRQPAARPHW---LRQRSKFHEGTPTSARGTRCCS 94


>gi|239742921 PREDICTED: hypothetical protein XP_002342685 [Homo
           sapiens]
          Length = 105

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 3/49 (6%)

Query: 454 LGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCT 502
           LG + S  C   E  R P A  +    L Q    HE TP S R T+CC+
Sbjct: 49  LGALCSPPCCSNEEPRQPAARPHW---LRQRSKFHEGTPTSARGTRCCS 94


>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
           sapiens]
          Length = 506

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 42/196 (21%), Positives = 72/196 (36%), Gaps = 25/196 (12%)

Query: 403 PLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCC 462
           PL + P N + +N + F Q GE         +    V Q      +  ++ L K+ SK  
Sbjct: 4   PLTDCPYNKVYKNLKEFSQNGEN------FCKQVTSVLQQRANLEISYAKGLQKLASKLS 57

Query: 463 KHPEAKRMPCAED---YLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDE 519
           K  +  R  C      + S  +     LH+K   +  +           +P +  L V E
Sbjct: 58  KALQNTRKSCVSSAWAWASEGMKSTADLHQKLGKAIELEAI--------KPTYQVLNVQE 109

Query: 520 -------TYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVK-HKPKATKEQLKAV 571
                    V K  N     ++  I    +     KK  AL +LV+  K   T+++ + +
Sbjct: 110 KKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKL 169

Query: 572 MDDFAAFVEKCCKADD 587
           ++      EK  K D+
Sbjct: 170 LNKLTKSTEKLEKEDE 185


>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
          Length = 2986

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 89/398 (22%), Positives = 141/398 (35%), Gaps = 55/398 (13%)

Query: 61   EDHVKLVNEVTEFAKT----CVADESAENCDKSLHTLFG--DKLCTVATLRETYGEMADC 114
            ED +KLVN    F KT    C   ES E   +      G  DKL   A +      ++  
Sbjct: 996  EDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKH 1055

Query: 115  CAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHD-NEETFLKKYLYEIARRHPYF 173
              ++E     C L  ++    L  + R  V +   A H    E  +K  L E+ +R    
Sbjct: 1056 LEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSVASHTRGPEQQVKAILSELLQRE--- 1112

Query: 174  YAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGK------ASSAKQRLKCASL 227
                +L F    K    +C Q           LD +++ G+       S+ +   +   L
Sbjct: 1113 --NRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEFYLSTHTSTGETTEETQEL 1170

Query: 228  QK-FGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAK 286
             K +GE             R P  +  E  KL+  L     E  H    E       + K
Sbjct: 1171 LKEYGE------------FRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDK 1218

Query: 287  YICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEA 346
            +   +      K +   EK L   +    ++E D +PA   SL+   V+ +D      E 
Sbjct: 1219 HY-RDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPA---SLSDREVKLRDANHEVNEE 1274

Query: 347  KDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVE 406
            K           + R  ++ +  LL+  K Y           D HEC      E    VE
Sbjct: 1275 K---------RKSARKKEFIMAELLQTEKAY---------VRDLHECLETYLWEMTSGVE 1316

Query: 407  E-PQNLIKQNCELFEQLGE-YKFQNALLVRYTKKVPQV 442
            E P  ++ +   +F  + E Y F N + ++  +K  Q+
Sbjct: 1317 EIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQL 1354


>gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]
          Length = 1663

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 89/398 (22%), Positives = 141/398 (35%), Gaps = 55/398 (13%)

Query: 61   EDHVKLVNEVTEFAKT----CVADESAENCDKSLHTLFG--DKLCTVATLRETYGEMADC 114
            ED +KLVN    F KT    C   ES E   +      G  DKL   A +      ++  
Sbjct: 996  EDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKH 1055

Query: 115  CAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHD-NEETFLKKYLYEIARRHPYF 173
              ++E     C L  ++    L  + R  V +   A H    E  +K  L E+ +R    
Sbjct: 1056 LEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSVASHTRGPEQQVKAILSELLQRE--- 1112

Query: 174  YAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGK------ASSAKQRLKCASL 227
                +L F    K    +C Q           LD +++ G+       S+ +   +   L
Sbjct: 1113 --NRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEFYLSTHTSTGETTEETQEL 1170

Query: 228  QK-FGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAK 286
             K +GE             R P  +  E  KL+  L     E  H    E       + K
Sbjct: 1171 LKEYGE------------FRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDK 1218

Query: 287  YICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEA 346
            +   +      K +   EK L   +    ++E D +PA   SL+   V+ +D      E 
Sbjct: 1219 HY-RDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPA---SLSDREVKLRDANHEVNEE 1274

Query: 347  KDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVE 406
            K           + R  ++ +  LL+  K Y           D HEC      E    VE
Sbjct: 1275 K---------RKSARKKEFIMAELLQTEKAY---------VRDLHECLETYLWEMTSGVE 1316

Query: 407  E-PQNLIKQNCELFEQLGE-YKFQNALLVRYTKKVPQV 442
            E P  ++ +   +F  + E Y F N + ++  +K  Q+
Sbjct: 1317 EIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQL 1354


>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
          Length = 1035

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 12/81 (14%)

Query: 526 FNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKC--C 583
           FN +    H ++C +SE ER++  + A  +L ++ PKA          +F ++ E C  C
Sbjct: 646 FNEDILCPHGELC-ISENERRLVSKEAWSKLQQYFPKA---------PEFPSYKECCSQC 695

Query: 584 KADDKETCFAEEGKKLVAASQ 604
           K  ++E    E   K++A  Q
Sbjct: 696 KILEREGEENEALHKMIANEQ 716


>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
          Length = 855

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 11/149 (7%)

Query: 391 HECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQ--VSTPTLV 448
           +E  A V  E K   E  QN+  Q   L + + EYKF+ A L++   ++ +  +S    V
Sbjct: 139 NERLASVAQELK---EINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQV 195

Query: 449 EVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNR 508
            V R   +V  +  KH E KR+    +YL+  L     L E   +S+R  +   E+L   
Sbjct: 196 SVLRQ-NQVEFEGLKH-EIKRLEEETEYLNSQLEDAIRLKE---ISERQLEEALETLKTE 250

Query: 509 RPCFSALEVDETYVPKEFNAETFTFHADI 537
           R   ++L  + ++     N   +T H  +
Sbjct: 251 REQKNSLRKELSHY-MSINDSFYTSHLHV 278


>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
          Length = 824

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 11/149 (7%)

Query: 391 HECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQ--VSTPTLV 448
           +E  A V  E K   E  QN+  Q   L + + EYKF+ A L++   ++ +  +S    V
Sbjct: 139 NERLASVAQELK---EINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQV 195

Query: 449 EVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNR 508
            V R   +V  +  KH E KR+    +YL+  L     L E   +S+R  +   E+L   
Sbjct: 196 SVLRQ-NQVEFEGLKH-EIKRLEEETEYLNSQLEDAIRLKE---ISERQLEEALETLKTE 250

Query: 509 RPCFSALEVDETYVPKEFNAETFTFHADI 537
           R   ++L  + ++     N   +T H  +
Sbjct: 251 REQKNSLRKELSHY-MSINDSFYTSHLHV 278


>gi|226371655 zinc finger family member 674 isoform 2 [Homo sapiens]
          Length = 575

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 21/109 (19%)

Query: 213 GKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHT----- 267
           GKA   KQ L+ +   + GE+ +K     ++        F + + LV    + HT     
Sbjct: 196 GKALHQKQALRKSQRSQTGEKLYKCTECGKV--------FIQKANLVVH-QRTHTGEKPY 246

Query: 268 ECCHGDLLECADDRADLAKYICENQDSISSKLKEC--CEKPLLEKSHCI 314
           ECC     ECA   +  +  I   +     K  EC  C K  ++KS  I
Sbjct: 247 ECC-----ECAKAFSQKSTLIAHQRTHTGEKPYECSECGKTFIQKSTLI 290


>gi|89994742 zinc finger family member 674 isoform 1 [Homo sapiens]
          Length = 581

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 29/109 (26%), Positives = 44/109 (40%), Gaps = 21/109 (19%)

Query: 213 GKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHT----- 267
           GKA   KQ L+ +   + GE+ +K     ++        F + + LV    + HT     
Sbjct: 202 GKALHQKQALRKSQRSQTGEKLYKCTECGKV--------FIQKANLVVH-QRTHTGEKPY 252

Query: 268 ECCHGDLLECADDRADLAKYICENQDSISSKLKEC--CEKPLLEKSHCI 314
           ECC     ECA   +  +  I   +     K  EC  C K  ++KS  I
Sbjct: 253 ECC-----ECAKAFSQKSTLIAHQRTHTGEKPYECSECGKTFIQKSTLI 296


>gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]
          Length = 1027

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 1/75 (1%)

Query: 445 PTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTES 504
           P LV++S  L  + ++  +    KR P    +L   L+Q  V+ E  P +D VT    + 
Sbjct: 701 PALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVI-EAFPPADNVTNLTVDM 759

Query: 505 LVNRRPCFSALEVDE 519
           L+      S L   +
Sbjct: 760 LIEPNGKISVLSTGD 774


>gi|12232475 IQ motif containing H isoform 2 [Homo sapiens]
          Length = 621

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 1/75 (1%)

Query: 445 PTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTES 504
           P LV++S  L  + ++  +    KR P    +L   L+Q  V+ E  P +D VT    + 
Sbjct: 362 PALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVI-EAFPPADNVTNLTVDM 420

Query: 505 LVNRRPCFSALEVDE 519
           L+      S L   +
Sbjct: 421 LIEPNGKISVLSTGD 435


>gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens]
          Length = 680

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 38/149 (25%), Positives = 54/149 (36%), Gaps = 19/149 (12%)

Query: 193 CQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEF 252
           C AA   A    +LDE    G    A+   +C SLQ           + R+S  F    F
Sbjct: 22  CLAAGPGAAAARRLDESLSAGSVQRARCASRCLSLQ-----------ITRISAFF--QHF 68

Query: 253 AEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICEN--QDSISSKLKECCEKPLLEK 310
                LV    + H +C     LE   +  DL K+ C++  +     K  EC       K
Sbjct: 69  QNNGSLV--WCQNHKQC--SKCLEPCKESGDLRKHQCQSFCEPLFPKKSYECLTSCEFLK 124

Query: 311 SHCIAEVENDEMPADLPSLAADFVESKDV 339
              + +  +   P      AA  VES +V
Sbjct: 125 YILLVKQGDCPAPEKASGFAAACVESCEV 153


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.133    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,526,400
Number of Sequences: 37866
Number of extensions: 1008101
Number of successful extensions: 2790
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2729
Number of HSP's gapped (non-prelim): 23
length of query: 609
length of database: 18,247,518
effective HSP length: 108
effective length of query: 501
effective length of database: 14,157,990
effective search space: 7093152990
effective search space used: 7093152990
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.