Guide to the Human Genome
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Search of human proteins with 4501953

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
         (318 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]             632   0.0  
gi|115305569 adenosine A1 receptor [Homo sapiens]                     301   4e-82
gi|4501947 adenosine A1 receptor [Homo sapiens]                       301   4e-82
gi|5921992 adenosine A2a receptor [Homo sapiens]                      244   6e-65
gi|4501951 adenosine A2b receptor [Homo sapiens]                      229   2e-60
gi|46559769 adenosine A3 receptor isoform 1 [Homo sapiens]            227   1e-59
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                123   2e-28
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]         112   4e-25
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]         112   4e-25
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]         112   4e-25
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]         112   4e-25
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]         112   4e-25
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]         112   4e-25
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]           111   7e-25
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]            111   7e-25
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]                110   2e-24
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]    108   5e-24
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]    108   5e-24
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]    108   5e-24
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]    108   5e-24
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]        108   8e-24
gi|4503383 dopamine receptor D1 [Homo sapiens]                        103   2e-22
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]               102   3e-22
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]      102   4e-22
gi|4885295 G protein-coupled receptor 12 [Homo sapiens]               100   1e-21
gi|28173558 trace amine associated receptor 6 [Homo sapiens]          100   2e-21
gi|110618256 trace amine associated receptor 9 [Homo sapiens]         100   2e-21
gi|15150803 opsin 4 isoform 1 [Homo sapiens]                          100   3e-21
gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo sa...    99   4e-21
gi|71999131 opsin 3 [Homo sapiens]                                     99   5e-21

>gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
          Length = 318

 Score =  632 bits (1631), Expect = 0.0
 Identities = 318/318 (100%), Positives = 318/318 (100%)

Query: 1   MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 60
           MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
Sbjct: 1   MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 60

Query: 61  VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR 120
           VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
Sbjct: 61  VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR 120

Query: 121 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF 180
           VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
Sbjct: 121 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF 180

Query: 181 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA 240
           SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
Sbjct: 181 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA 240

Query: 241 LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC 300
           LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
Sbjct: 241 LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC 300

Query: 301 VVCHPSDSLDTSIEKNSE 318
           VVCHPSDSLDTSIEKNSE
Sbjct: 301 VVCHPSDSLDTSIEKNSE 318


>gi|115305569 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score =  301 bits (772), Expect = 4e-82
 Identities = 153/316 (48%), Positives = 217/316 (68%), Gaps = 9/316 (2%)

Query: 7   ALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVM 66
           ++S     YI +E+ I L ++ GNVLVI  VK+N +L+  TF FIVSLA+AD+AVG LV+
Sbjct: 4   SISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVI 63

Query: 67  PLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRR 126
           PLAI++++G   +F++CL + C +LI T +SI++LLAIAVDRYLRVK+ +RYK V T RR
Sbjct: 64  PLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRR 123

Query: 127 IWLALGLCWLVSFLVGLTPMFGWNMKLTSEY------HRNVTFLSCQFVSVMRMDYMVYF 180
             +A+  CW++SF+VGLTPMFGWN     E             + C+F  V+ M+YMVYF
Sbjct: 124 AAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYF 183

Query: 181 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLS-NSKETGAFYGREFKTAKSLFLVLFLF 239
           +F  W+  PL++M  IYL++FY+IR +L+  +S +S +   +YG+E K AKSL L+LFLF
Sbjct: 184 NFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLF 243

Query: 240 ALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLIL 297
           ALSWLPL I+NCI  F  +   P ++ Y+ I L+H NS MNPIVYA++I+KF+ T+L I 
Sbjct: 244 ALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIW 303

Query: 298 KACVVCHPSDSLDTSI 313
                C P+  +D  +
Sbjct: 304 NDHFRCQPAPPIDEDL 319


>gi|4501947 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score =  301 bits (772), Expect = 4e-82
 Identities = 153/316 (48%), Positives = 217/316 (68%), Gaps = 9/316 (2%)

Query: 7   ALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVM 66
           ++S     YI +E+ I L ++ GNVLVI  VK+N +L+  TF FIVSLA+AD+AVG LV+
Sbjct: 4   SISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVI 63

Query: 67  PLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRR 126
           PLAI++++G   +F++CL + C +LI T +SI++LLAIAVDRYLRVK+ +RYK V T RR
Sbjct: 64  PLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRR 123

Query: 127 IWLALGLCWLVSFLVGLTPMFGWNMKLTSEY------HRNVTFLSCQFVSVMRMDYMVYF 180
             +A+  CW++SF+VGLTPMFGWN     E             + C+F  V+ M+YMVYF
Sbjct: 124 AAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYF 183

Query: 181 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLS-NSKETGAFYGREFKTAKSLFLVLFLF 239
           +F  W+  PL++M  IYL++FY+IR +L+  +S +S +   +YG+E K AKSL L+LFLF
Sbjct: 184 NFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLF 243

Query: 240 ALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLIL 297
           ALSWLPL I+NCI  F  +   P ++ Y+ I L+H NS MNPIVYA++I+KF+ T+L I 
Sbjct: 244 ALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIW 303

Query: 298 KACVVCHPSDSLDTSI 313
                C P+  +D  +
Sbjct: 304 NDHFRCQPAPPIDEDL 319


>gi|5921992 adenosine A2a receptor [Homo sapiens]
          Length = 412

 Score =  244 bits (624), Expect = 6e-65
 Identities = 127/305 (41%), Positives = 192/305 (62%), Gaps = 12/305 (3%)

Query: 10  LANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLA 69
           + +  YIT+E+ I + AI+GNVLV   V LN +LQ  T YF+VSLA ADIAVGVL +P A
Sbjct: 4   MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFA 63

Query: 70  IVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWL 129
           I +S G     + CLF+ C +L+ T +SI SLLAIA+DRY+ +++ +RY  + T  R   
Sbjct: 64  ITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKG 123

Query: 130 ALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVT------FLSCQFVSVMRMDYMVYFSFL 183
            + +CW++SF +GLTPM GWN     +  +N +       ++C F  V+ M+YMVYF+F 
Sbjct: 124 IIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFF 183

Query: 184 TWIFIPLVVMCAIYLDIFYIIRNKLSLNLSN---SKETGAFYGREFKTAKSLFLVLFLFA 240
             + +PL++M  +YL IF   R +L    S     +   +   +E   AKSL +++ LFA
Sbjct: 184 ACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFA 243

Query: 241 LSWLPLSIINCIIYF---NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLIL 297
           L WLPL IINC  +F       P  ++Y+ I+LSH NS++NP +YAY+I++F++T+  I+
Sbjct: 244 LCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKII 303

Query: 298 KACVV 302
           ++ V+
Sbjct: 304 RSHVL 308


>gi|4501951 adenosine A2b receptor [Homo sapiens]
          Length = 332

 Score =  229 bits (584), Expect = 2e-60
 Identities = 122/312 (39%), Positives = 184/312 (58%), Gaps = 19/312 (6%)

Query: 8   LSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMP 67
           L   +  Y+ +E+ I   ++ GNVLV   V    +LQT T YF+VSLA AD+AVG+  +P
Sbjct: 3   LETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIP 62

Query: 68  LAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRI 127
            AI +SLG    FY CLF+ C +L+ T +SI SLLA+AVDRYL + + +RYK + T  R 
Sbjct: 63  FAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRA 122

Query: 128 WLALGLCWLVSFLVGLTPMFGWNMKLTS----------EYHRNVTFLSCQFVSVMRMDYM 177
              + + W+++F +GLTP  GWN K ++            + +   + C F +V+ M YM
Sbjct: 123 RGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYM 182

Query: 178 VYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLN--LSNSKETGAFYGREFKTAKSLFLV 235
           VYF+F   +  PL++M  IY+ IF +   +L     + +S+ T     RE   AKSL ++
Sbjct: 183 VYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTT---LQREIHAAKSLAMI 239

Query: 236 LFLFALSWLPLSIINCIIYF----NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKE 291
           + +FAL WLP+  +NC+  F        P+  + M ILLSHANS++NPIVYAY+ + F+ 
Sbjct: 240 VGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRY 299

Query: 292 TYLLILKACVVC 303
           T+  I+   ++C
Sbjct: 300 TFHKIISRYLLC 311


>gi|46559769 adenosine A3 receptor isoform 1 [Homo sapiens]
          Length = 347

 Score =  227 bits (578), Expect = 1e-59
 Identities = 117/119 (98%), Positives = 119/119 (100%)

Query: 1   MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 60
           MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
Sbjct: 1   MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 60

Query: 61  VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYK 119
           VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVR++
Sbjct: 61  VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFR 119


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score =  123 bits (309), Expect = 2e-28
 Identities = 101/346 (29%), Positives = 160/346 (46%), Gaps = 60/346 (17%)

Query: 2   PNNSTALSLANVTYITMEIFIGLC-------AIVGNVLVICVVKLNPSLQTTTFYFIVSL 54
           PN +++ S      IT  I +GL        AIVGN+LVI  V  N  L+T T YFIV+L
Sbjct: 28  PNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNL 87

Query: 55  ALADIAVGVLVMPLAIVVS-LGI-TIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRV 112
           A+AD+ +   V+P +  +  LG   +    C     + ++   ASI+SL AI++DRY+ V
Sbjct: 88  AMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGV 147

Query: 113 KLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVM 172
           + +++Y  + T R+  LAL   W++S ++ + P+ GW     ++              V 
Sbjct: 148 RYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKE---------CGVT 198

Query: 173 RMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNL--------SNSKETGA---- 220
              +   FS L   +IPL V+  +Y  + YI+  + + NL        SNSKE       
Sbjct: 199 EEPFYALFSSLGSFYIPLAVILVMYCRV-YIVAKRTTKNLEAGVMKEMSNSKELTLRIHS 257

Query: 221 ---------------------------FYGREFKTAKSLFLVLFLFALSWLPLSIINCI- 252
                                       + RE K AK+L +V+ +F L WLP  I   + 
Sbjct: 258 KNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLG 317

Query: 253 -IYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLIL 297
            ++   + P  V  +   L + NS +NPI+Y    K+FK  ++ IL
Sbjct: 318 SLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRIL 363


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score =  112 bits (280), Expect = 4e-25
 Identities = 97/315 (30%), Positives = 148/315 (46%), Gaps = 29/315 (9%)

Query: 9   SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
           S+  V  +T    + L AI+GN+LV+  V  +  L+   T YFIVSLA AD+ V VLVMP
Sbjct: 16  SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75

Query: 68  LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKL-TVRYKRVTT 123
               + L   I  Y    CL  T L ++ T ASI  L  I++DRY  +    + Y+   T
Sbjct: 76  FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134

Query: 124 HRRIWLALGLCWLVSFLVGLTP-MFGWN----MKLTSEYHRNVTFLSCQFVSVMRMDYMV 178
             RI L LG CW++   +   P M GWN    + L  +   N    S   V ++   Y +
Sbjct: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194

Query: 179 YFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAF---------------YG 223
             S + + +IP ++M   Y  I Y+   + +  +   +  GA                  
Sbjct: 195 TCSVVAF-YIPFLLMVLAYYRI-YVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252

Query: 224 REFKTAKSLFLVLFLFALSWLPLSIINCI-IYFNGEVPQLVLYMGILLSHANSMMNPIVY 282
            E K AK+L +++  F L W P  + N +  + +  VP  V    + L + NS +NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312

Query: 283 AYKIKKFKETYLLIL 297
           A+  K F+  +L+IL
Sbjct: 313 AFLNKSFRRAFLIIL 327


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score =  112 bits (280), Expect = 4e-25
 Identities = 97/315 (30%), Positives = 148/315 (46%), Gaps = 29/315 (9%)

Query: 9   SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
           S+  V  +T    + L AI+GN+LV+  V  +  L+   T YFIVSLA AD+ V VLVMP
Sbjct: 16  SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75

Query: 68  LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKL-TVRYKRVTT 123
               + L   I  Y    CL  T L ++ T ASI  L  I++DRY  +    + Y+   T
Sbjct: 76  FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134

Query: 124 HRRIWLALGLCWLVSFLVGLTP-MFGWN----MKLTSEYHRNVTFLSCQFVSVMRMDYMV 178
             RI L LG CW++   +   P M GWN    + L  +   N    S   V ++   Y +
Sbjct: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194

Query: 179 YFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAF---------------YG 223
             S + + +IP ++M   Y  I Y+   + +  +   +  GA                  
Sbjct: 195 TCSVVAF-YIPFLLMVLAYYRI-YVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252

Query: 224 REFKTAKSLFLVLFLFALSWLPLSIINCI-IYFNGEVPQLVLYMGILLSHANSMMNPIVY 282
            E K AK+L +++  F L W P  + N +  + +  VP  V    + L + NS +NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312

Query: 283 AYKIKKFKETYLLIL 297
           A+  K F+  +L+IL
Sbjct: 313 AFLNKSFRRAFLIIL 327


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score =  112 bits (280), Expect = 4e-25
 Identities = 97/315 (30%), Positives = 148/315 (46%), Gaps = 29/315 (9%)

Query: 9   SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
           S+  V  +T    + L AI+GN+LV+  V  +  L+   T YFIVSLA AD+ V VLVMP
Sbjct: 16  SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75

Query: 68  LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKL-TVRYKRVTT 123
               + L   I  Y    CL  T L ++ T ASI  L  I++DRY  +    + Y+   T
Sbjct: 76  FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134

Query: 124 HRRIWLALGLCWLVSFLVGLTP-MFGWN----MKLTSEYHRNVTFLSCQFVSVMRMDYMV 178
             RI L LG CW++   +   P M GWN    + L  +   N    S   V ++   Y +
Sbjct: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194

Query: 179 YFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAF---------------YG 223
             S + + +IP ++M   Y  I Y+   + +  +   +  GA                  
Sbjct: 195 TCSVVAF-YIPFLLMVLAYYRI-YVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252

Query: 224 REFKTAKSLFLVLFLFALSWLPLSIINCI-IYFNGEVPQLVLYMGILLSHANSMMNPIVY 282
            E K AK+L +++  F L W P  + N +  + +  VP  V    + L + NS +NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312

Query: 283 AYKIKKFKETYLLIL 297
           A+  K F+  +L+IL
Sbjct: 313 AFLNKSFRRAFLIIL 327


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score =  112 bits (280), Expect = 4e-25
 Identities = 97/315 (30%), Positives = 148/315 (46%), Gaps = 29/315 (9%)

Query: 9   SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
           S+  V  +T    + L AI+GN+LV+  V  +  L+   T YFIVSLA AD+ V VLVMP
Sbjct: 16  SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75

Query: 68  LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKL-TVRYKRVTT 123
               + L   I  Y    CL  T L ++ T ASI  L  I++DRY  +    + Y+   T
Sbjct: 76  FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134

Query: 124 HRRIWLALGLCWLVSFLVGLTP-MFGWN----MKLTSEYHRNVTFLSCQFVSVMRMDYMV 178
             RI L LG CW++   +   P M GWN    + L  +   N    S   V ++   Y +
Sbjct: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194

Query: 179 YFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAF---------------YG 223
             S + + +IP ++M   Y  I Y+   + +  +   +  GA                  
Sbjct: 195 TCSVVAF-YIPFLLMVLAYYRI-YVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252

Query: 224 REFKTAKSLFLVLFLFALSWLPLSIINCI-IYFNGEVPQLVLYMGILLSHANSMMNPIVY 282
            E K AK+L +++  F L W P  + N +  + +  VP  V    + L + NS +NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312

Query: 283 AYKIKKFKETYLLIL 297
           A+  K F+  +L+IL
Sbjct: 313 AFLNKSFRRAFLIIL 327


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score =  112 bits (280), Expect = 4e-25
 Identities = 97/315 (30%), Positives = 148/315 (46%), Gaps = 29/315 (9%)

Query: 9   SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
           S+  V  +T    + L AI+GN+LV+  V  +  L+   T YFIVSLA AD+ V VLVMP
Sbjct: 16  SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75

Query: 68  LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKL-TVRYKRVTT 123
               + L   I  Y    CL  T L ++ T ASI  L  I++DRY  +    + Y+   T
Sbjct: 76  FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134

Query: 124 HRRIWLALGLCWLVSFLVGLTP-MFGWN----MKLTSEYHRNVTFLSCQFVSVMRMDYMV 178
             RI L LG CW++   +   P M GWN    + L  +   N    S   V ++   Y +
Sbjct: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194

Query: 179 YFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAF---------------YG 223
             S + + +IP ++M   Y  I Y+   + +  +   +  GA                  
Sbjct: 195 TCSVVAF-YIPFLLMVLAYYRI-YVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252

Query: 224 REFKTAKSLFLVLFLFALSWLPLSIINCI-IYFNGEVPQLVLYMGILLSHANSMMNPIVY 282
            E K AK+L +++  F L W P  + N +  + +  VP  V    + L + NS +NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312

Query: 283 AYKIKKFKETYLLIL 297
           A+  K F+  +L+IL
Sbjct: 313 AFLNKSFRRAFLIIL 327


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score =  112 bits (280), Expect = 4e-25
 Identities = 97/315 (30%), Positives = 148/315 (46%), Gaps = 29/315 (9%)

Query: 9   SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
           S+  V  +T    + L AI+GN+LV+  V  +  L+   T YFIVSLA AD+ V VLVMP
Sbjct: 16  SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75

Query: 68  LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKL-TVRYKRVTT 123
               + L   I  Y    CL  T L ++ T ASI  L  I++DRY  +    + Y+   T
Sbjct: 76  FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134

Query: 124 HRRIWLALGLCWLVSFLVGLTP-MFGWN----MKLTSEYHRNVTFLSCQFVSVMRMDYMV 178
             RI L LG CW++   +   P M GWN    + L  +   N    S   V ++   Y +
Sbjct: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAI 194

Query: 179 YFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAF---------------YG 223
             S + + +IP ++M   Y  I Y+   + +  +   +  GA                  
Sbjct: 195 TCSVVAF-YIPFLLMVLAYYRI-YVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252

Query: 224 REFKTAKSLFLVLFLFALSWLPLSIINCI-IYFNGEVPQLVLYMGILLSHANSMMNPIVY 282
            E K AK+L +++  F L W P  + N +  + +  VP  V    + L + NS +NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312

Query: 283 AYKIKKFKETYLLIL 297
           A+  K F+  +L+IL
Sbjct: 313 AFLNKSFRRAFLIIL 327


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score =  111 bits (278), Expect = 7e-25
 Identities = 95/325 (29%), Positives = 156/325 (48%), Gaps = 27/325 (8%)

Query: 4   NSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGV 63
           +STA  +     + + I I    + GNV+V   V LN  L+  T  FIVSLA+ D+ +G+
Sbjct: 13  DSTACKITITVVLAVLILI---TVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGL 69

Query: 64  LVMPLAIVVSLGITIHF--YSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRV 121
           LV+P + +  L     F    C   T L ++   ASI++L  I++DRY  V   +RY  +
Sbjct: 70  LVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVL 129

Query: 122 TTHRRIWLALGLCWLVSFLVG-LTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF 180
            T  R+ ++L L W++S  +  L+   GWN +       N T   C+ V V  +  +V  
Sbjct: 130 VTPVRVAISLVLIWVISITLSFLSIHLGWNSR-NETSKGNHTTSKCK-VQVNEVYGLV-- 185

Query: 181 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA 240
             L   ++PL++MC  Y  IF + R++ +  +++     A   RE K   +L  V+  F 
Sbjct: 186 DGLVTFYLPLLIMCITYYRIFKVARDQ-AKRINHISSWKAATIREHKATVTLAAVMGAFI 244

Query: 241 LSWLPLSIINCIIY--------FNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKET 292
           + W P       +Y         N  +  +VL++G    +ANS +NPI+YA   + F+  
Sbjct: 245 ICWFP--YFTAFVYRGLRGDDAINEVLEAIVLWLG----YANSALNPILYAALNRDFRTG 298

Query: 293 YLLILKACVVCHPSDSLDTSIEKNS 317
           Y  +   C      +S  TS+  N+
Sbjct: 299 YQQLF--CCRLANRNSHKTSLRSNA 321


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score =  111 bits (278), Expect = 7e-25
 Identities = 95/325 (29%), Positives = 156/325 (48%), Gaps = 27/325 (8%)

Query: 4   NSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGV 63
           +STA  +     + + I I    + GNV+V   V LN  L+  T  FIVSLA+ D+ +G+
Sbjct: 13  DSTACKITITVVLAVLILI---TVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGL 69

Query: 64  LVMPLAIVVSLGITIHF--YSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRV 121
           LV+P + +  L     F    C   T L ++   ASI++L  I++DRY  V   +RY  +
Sbjct: 70  LVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVL 129

Query: 122 TTHRRIWLALGLCWLVSFLVG-LTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF 180
            T  R+ ++L L W++S  +  L+   GWN +       N T   C+ V V  +  +V  
Sbjct: 130 VTPVRVAISLVLIWVISITLSFLSIHLGWNSR-NETSKGNHTTSKCK-VQVNEVYGLV-- 185

Query: 181 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA 240
             L   ++PL++MC  Y  IF + R++ +  +++     A   RE K   +L  V+  F 
Sbjct: 186 DGLVTFYLPLLIMCITYYRIFKVARDQ-AKRINHISSWKAATIREHKATVTLAAVMGAFI 244

Query: 241 LSWLPLSIINCIIY--------FNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKET 292
           + W P       +Y         N  +  +VL++G    +ANS +NPI+YA   + F+  
Sbjct: 245 ICWFP--YFTAFVYRGLRGDDAINEVLEAIVLWLG----YANSALNPILYAALNRDFRTG 298

Query: 293 YLLILKACVVCHPSDSLDTSIEKNS 317
           Y  +   C      +S  TS+  N+
Sbjct: 299 YQQLF--CCRLANRNSHKTSLRSNA 321


>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
          Length = 572

 Score =  110 bits (274), Expect = 2e-24
 Identities = 83/326 (25%), Positives = 145/326 (44%), Gaps = 66/326 (20%)

Query: 24  LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYS- 82
           L A+ GN+LVI  V  N  LQT T YFIV+LA+AD+ +   V+P +  + +   + F++ 
Sbjct: 108 LMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEV---LGFWAF 164

Query: 83  ----CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVS 138
               C     + ++   ASI+SL  I+VDRY+ V+ +++Y  + T R+    L L W+V+
Sbjct: 165 GRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVA 224

Query: 139 FLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYL 198
            +V + P+ GW   +  +          +F  +        FS +   ++P+ V+  +Y 
Sbjct: 225 LVVSVGPLLGWKEPVPPDE---------RFCGITEEAGYAVFSSVCSFYLPMAVIVVMYC 275

Query: 199 DIFYIIRNKL-SLNLSNSKETGAF------------------------------------ 221
            ++ + R+   SL     +E G                                      
Sbjct: 276 RVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSV 335

Query: 222 ----YGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGIL-----LSH 272
               + RE K AK+L +V+ +F L W P      ++      PQL    G+      L +
Sbjct: 336 RLLKFSREKKAAKTLAIVVGVFVLCWFPFFF---VLPLGSLFPQLKPSEGVFKVIFWLGY 392

Query: 273 ANSMMNPIVYAYKIKKFKETYLLILK 298
            NS +NP++Y    ++FK  +L +L+
Sbjct: 393 FNSCVNPLIYPCSSREFKRAFLRLLR 418


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score =  108 bits (271), Expect = 5e-24
 Identities = 85/324 (26%), Positives = 146/324 (45%), Gaps = 48/324 (14%)

Query: 24  LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPL-AIVVSLGI-TIHFY 81
           L  ++GN+LVI  V  +  L + T Y+IV+LA+AD+ +   V+P  AI   LG       
Sbjct: 38  LFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRV 97

Query: 82  SCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLV 141
            C     + ++   ASIM L  I++DRY+ V   +RY  + T RR  +AL   W +S ++
Sbjct: 98  FCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVI 157

Query: 142 GLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIF 201
            + P+FGW      +         CQ   +      V FS L   ++PL ++  +Y  ++
Sbjct: 158 SIGPLFGWRQPAPEDE------TICQ---INEEPGYVLFSALGSFYLPLAIILVMYCRVY 208

Query: 202 YIIRNK-------------------LSLNLSNSKETGA----------------FYGREF 226
            + + +                   L ++  N+   G+                 + RE 
Sbjct: 209 VVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREK 268

Query: 227 KTAKSLFLVLFLFALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAY 284
           K AK+L +V+  F L WLP  ++  I  F  + +  + V  +   L + NS +NPI+Y  
Sbjct: 269 KAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPC 328

Query: 285 KIKKFKETYLLILKACVVCHPSDS 308
             ++FK+ +  +L+   +C    S
Sbjct: 329 SSQEFKKAFQNVLRIQCLCRKQSS 352


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score =  108 bits (271), Expect = 5e-24
 Identities = 85/324 (26%), Positives = 146/324 (45%), Gaps = 48/324 (14%)

Query: 24  LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPL-AIVVSLGI-TIHFY 81
           L  ++GN+LVI  V  +  L + T Y+IV+LA+AD+ +   V+P  AI   LG       
Sbjct: 38  LFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRV 97

Query: 82  SCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLV 141
            C     + ++   ASIM L  I++DRY+ V   +RY  + T RR  +AL   W +S ++
Sbjct: 98  FCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVI 157

Query: 142 GLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIF 201
            + P+FGW      +         CQ   +      V FS L   ++PL ++  +Y  ++
Sbjct: 158 SIGPLFGWRQPAPEDE------TICQ---INEEPGYVLFSALGSFYLPLAIILVMYCRVY 208

Query: 202 YIIRNK-------------------LSLNLSNSKETGA----------------FYGREF 226
            + + +                   L ++  N+   G+                 + RE 
Sbjct: 209 VVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREK 268

Query: 227 KTAKSLFLVLFLFALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAY 284
           K AK+L +V+  F L WLP  ++  I  F  + +  + V  +   L + NS +NPI+Y  
Sbjct: 269 KAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPC 328

Query: 285 KIKKFKETYLLILKACVVCHPSDS 308
             ++FK+ +  +L+   +C    S
Sbjct: 329 SSQEFKKAFQNVLRIQCLCRKQSS 352


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score =  108 bits (271), Expect = 5e-24
 Identities = 85/324 (26%), Positives = 146/324 (45%), Gaps = 48/324 (14%)

Query: 24  LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPL-AIVVSLGI-TIHFY 81
           L  ++GN+LVI  V  +  L + T Y+IV+LA+AD+ +   V+P  AI   LG       
Sbjct: 38  LFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRV 97

Query: 82  SCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLV 141
            C     + ++   ASIM L  I++DRY+ V   +RY  + T RR  +AL   W +S ++
Sbjct: 98  FCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVI 157

Query: 142 GLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIF 201
            + P+FGW      +         CQ   +      V FS L   ++PL ++  +Y  ++
Sbjct: 158 SIGPLFGWRQPAPEDE------TICQ---INEEPGYVLFSALGSFYLPLAIILVMYCRVY 208

Query: 202 YIIRNK-------------------LSLNLSNSKETGA----------------FYGREF 226
            + + +                   L ++  N+   G+                 + RE 
Sbjct: 209 VVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREK 268

Query: 227 KTAKSLFLVLFLFALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAY 284
           K AK+L +V+  F L WLP  ++  I  F  + +  + V  +   L + NS +NPI+Y  
Sbjct: 269 KAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPC 328

Query: 285 KIKKFKETYLLILKACVVCHPSDS 308
             ++FK+ +  +L+   +C    S
Sbjct: 329 SSQEFKKAFQNVLRIQCLCRKQSS 352


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score =  108 bits (271), Expect = 5e-24
 Identities = 85/324 (26%), Positives = 146/324 (45%), Gaps = 48/324 (14%)

Query: 24  LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPL-AIVVSLGI-TIHFY 81
           L  ++GN+LVI  V  +  L + T Y+IV+LA+AD+ +   V+P  AI   LG       
Sbjct: 38  LFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRV 97

Query: 82  SCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLV 141
            C     + ++   ASIM L  I++DRY+ V   +RY  + T RR  +AL   W +S ++
Sbjct: 98  FCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVI 157

Query: 142 GLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIF 201
            + P+FGW      +         CQ   +      V FS L   ++PL ++  +Y  ++
Sbjct: 158 SIGPLFGWRQPAPEDE------TICQ---INEEPGYVLFSALGSFYLPLAIILVMYCRVY 208

Query: 202 YIIRNK-------------------LSLNLSNSKETGA----------------FYGREF 226
            + + +                   L ++  N+   G+                 + RE 
Sbjct: 209 VVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREK 268

Query: 227 KTAKSLFLVLFLFALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAY 284
           K AK+L +V+  F L WLP  ++  I  F  + +  + V  +   L + NS +NPI+Y  
Sbjct: 269 KAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPC 328

Query: 285 KIKKFKETYLLILKACVVCHPSDS 308
             ++FK+ +  +L+   +C    S
Sbjct: 329 SSQEFKKAFQNVLRIQCLCRKQSS 352


>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
          Length = 402

 Score =  108 bits (269), Expect = 8e-24
 Identities = 98/329 (29%), Positives = 149/329 (45%), Gaps = 43/329 (13%)

Query: 9   SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
           S+  V  +T    + L AI+GN+LV+  V  +  L+   T YFIVSLA AD+ V VLVMP
Sbjct: 16  SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75

Query: 68  LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKL-TVRYKRVTT 123
               + L   I  Y    CL  T L ++ T ASI  L  I++DRY  +    + Y+   T
Sbjct: 76  FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134

Query: 124 HRRIWLALGLCWLVSFLVGLTP-MFGW------------NMKLTSEYHR------NVTFL 164
             RI L LG CW++   +   P M GW            N  L  ++H       N    
Sbjct: 135 PLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSN 194

Query: 165 SCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAF--- 221
           S   V ++   Y +  S + + +IP ++M   Y  I Y+   + +  +   +  GA    
Sbjct: 195 STYCVFMVNKPYAITCSVVAF-YIPFLLMVLAYYRI-YVTAKEHAHQIQMLQRAGASSES 252

Query: 222 ------------YGREFKTAKSLFLVLFLFALSWLPLSIINCI-IYFNGEVPQLVLYMGI 268
                          E K AK+L +++  F L W P  + N +  + +  VP  V    +
Sbjct: 253 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFL 312

Query: 269 LLSHANSMMNPIVYAYKIKKFKETYLLIL 297
            L + NS +NP +YA+  K F+  +L+IL
Sbjct: 313 WLGYINSGLNPFLYAFLNKSFRRAFLIIL 341


>gi|4503383 dopamine receptor D1 [Homo sapiens]
          Length = 446

 Score =  103 bits (258), Expect = 2e-22
 Identities = 85/335 (25%), Positives = 155/335 (46%), Gaps = 45/335 (13%)

Query: 24  LCAIVGNVLVIC-VVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYS 82
           L  ++GN LV   V++        T +F++SLA++D+ V VLVMP   V  +     F S
Sbjct: 35  LSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGS 94

Query: 83  -CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLV 141
            C       ++ + ASI++L  I+VDRY  +    RY+R  T +  ++ + + W +S L+
Sbjct: 95  FCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLI 154

Query: 142 GLTPM-FGWNM-KLTSEYHRNVTFLS-----CQFVSVMRMDYMVYFSFLTWIFIPLVVMC 194
              P+   W+  K TS    N T L+     C   S +   Y +  S +++ +IP+ +M 
Sbjct: 155 SFIPVQLSWHKAKPTSPSDGNATSLAETIDNCD--SSLSRTYAISSSVISF-YIPVAIMI 211

Query: 195 AIYLDIFYIIRNKL---------SLNLSNSKETGA----------------FYGREFKTA 229
             Y  I+ I + ++         +++  N + T                   + RE K  
Sbjct: 212 VTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVL 271

Query: 230 KSLFLVLFLFALSWLPLSIINCIIYFNGE-------VPQLVLYMGILLSHANSMMNPIVY 282
           K+L +++ +F   WLP  I+NCI+ F G        +      + +    ANS +NPI+Y
Sbjct: 272 KTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIY 331

Query: 283 AYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNS 317
           A+    F++ +  +L    +C  +++   ++  N+
Sbjct: 332 AFN-ADFRKAFSTLLGCYRLCPATNNAIETVSINN 365


>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
          Length = 408

 Score =  102 bits (255), Expect = 3e-22
 Identities = 95/326 (29%), Positives = 144/326 (44%), Gaps = 60/326 (18%)

Query: 24  LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHF--- 80
           L  + GN+LVI  +   P LQT T  F+ SLA AD+ +G+LV+P A   +L +T H+   
Sbjct: 49  LATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPA--ATLALTGHWPLG 106

Query: 81  -YSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSF 139
              C   T + ++   ASI +L A+AVDRYL V   +RY  + T R    A+ L W+VS 
Sbjct: 107 ATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSA 166

Query: 140 LVGLTPMFG--WNMKLTSEYHR-NVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAI 196
            V   P+    W +   +E  R +     C F S   M Y++  S +++ ++PL+VM  +
Sbjct: 167 AVSFAPIMSQWWRVGADAEAQRCHSNPRCCAFAS--NMPYVLLSSSVSF-YLPLLVMLFV 223

Query: 197 YLDIFYIIRNKLSLNLSNSKETGAFYG--------------------------------- 223
           Y  +F +   +L L      E G F                                   
Sbjct: 224 YARVFVVATRQLRLLRG---ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPA 280

Query: 224 -----REFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGIL----LSHAN 274
                RE +   +L L++  F L WLP  + N +    G  P LV     L    L +AN
Sbjct: 281 RLLPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALGG--PSLVPGPAFLALNWLGYAN 338

Query: 275 SMMNPIVYAYKIKKFKETYLLILKAC 300
           S  NP++Y  +   F+  +  +L  C
Sbjct: 339 SAFNPLIYC-RSPDFRSAFRRLLCRC 363


>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
          Length = 413

 Score =  102 bits (254), Expect = 4e-22
 Identities = 81/293 (27%), Positives = 138/293 (47%), Gaps = 30/293 (10%)

Query: 16  ITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPL--AIVVS 73
           I M + + L  + GNVLVI  +     LQT T YFI SLA AD+ +G+ V+P   A ++ 
Sbjct: 38  IVMSLIV-LAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILM 96

Query: 74  LGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGL 133
              T   + C F T + ++   ASI +L  IAVDRY  +    +Y+ + T  +  + + +
Sbjct: 97  KMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILM 156

Query: 134 CWLVSFLVGLTPMFGWNMKLTSEYHRN--VTFLSCQFVSVMRMDYMVYFSFLTWIFIPLV 191
            W+VS L    P+     + T +   N       C F +     Y +  S +++ ++PLV
Sbjct: 157 VWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFT--NQAYAIASSIVSF-YVPLV 213

Query: 192 VMCAIYLDIFYIIRNKLS-----------LNLSNSKETG----------AFYGREFKTAK 230
           +M  +Y  +F   + +L             NLS  ++ G           F  +E K  K
Sbjct: 214 IMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALK 273

Query: 231 SLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGI-LLSHANSMMNPIVY 282
           +L +++  F L WLP  I+N +      + +  +Y+ +  + + NS  NP++Y
Sbjct: 274 TLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIY 326


>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
          Length = 334

 Score =  100 bits (250), Expect = 1e-21
 Identities = 70/273 (25%), Positives = 134/273 (49%), Gaps = 15/273 (5%)

Query: 30  NVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCL 89
           N +V+ ++  NPSL+   F  I SLALAD+  G+ ++   +   L   +   +   +T  
Sbjct: 62  NAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLITNFVFAYL---LQSEATKLVTIG 118

Query: 90  LLIFTH-ASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFG 148
           L++ +  AS+ SLLAI VDRYL +   + Y    T    ++ L + W  S  +GL P+ G
Sbjct: 119 LIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGLLPVMG 178

Query: 149 WNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKL 208
           WN          V  L+    +++ + ++  F+ +  ++I +   C I      ++R+  
Sbjct: 179 WNCLRDESTCSVVRPLTKNNAAILSVSFLFMFALMLQLYIQI---CKI------VMRHAH 229

Query: 209 SLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGI 268
            + L +     + Y    K   +L ++L  FA  W+P ++ + I  +    P +  Y  +
Sbjct: 230 QIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYT--YPSIYTYATL 287

Query: 269 LLSHANSMMNPIVYAYKIKKFKETYLLILKACV 301
           L +  NS++NP++YA++ ++ ++   LI   C+
Sbjct: 288 LPATYNSIINPVIYAFRNQEIQKALCLICCGCI 320


>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
          Length = 345

 Score =  100 bits (249), Expect = 2e-21
 Identities = 89/309 (28%), Positives = 147/309 (47%), Gaps = 29/309 (9%)

Query: 21  FIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHF 80
           F  + A+ GN+LV+  +     L + T + + SLA AD  VGV VMP ++V ++    +F
Sbjct: 41  FGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYF 100

Query: 81  --YSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVS 138
               C F TC  + F ++S+  L  I++DRY+ V   + Y    T        G+C  VS
Sbjct: 101 GRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVS----VSGICISVS 156

Query: 139 FLVGLTPMFGWNMKLTSEYHRNVTFLS--------CQFVSVMRMDYMVYFSFLTWIFIPL 190
           +++ L  M+   +  T  Y   +  LS        CQ V         + SF    FIP 
Sbjct: 157 WILPL--MYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLSF----FIPT 210

Query: 191 VVMCAIYLDIFYIIR---NKLSLNLSNSKETGAFY-----GREFKTAKSLFLVLFLFALS 242
            +M  +Y +IF + R    K+    S ++ +   Y      RE K AK+L + +  F +S
Sbjct: 211 FIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMIS 270

Query: 243 WLPLSIINCIIYFNGEV-PQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACV 301
           WLP SI + I  F G + P  +  +    ++ NS MNP++YA     F++   +I+   V
Sbjct: 271 WLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQV 330

Query: 302 VCHPSDSLD 310
           + + S +++
Sbjct: 331 LKNSSATMN 339


>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
          Length = 348

 Score =  100 bits (249), Expect = 2e-21
 Identities = 92/307 (29%), Positives = 145/307 (47%), Gaps = 21/307 (6%)

Query: 21  FIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHF 80
           F  + A  GN+LV+  +     L T T + I SLA AD  VGV VMP + V S+    +F
Sbjct: 41  FGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYF 100

Query: 81  YS--CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVS 138
               C F TC    F  AS+  L  I+VDRY+ V   + Y    T     + + L W  S
Sbjct: 101 GDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFS 160

Query: 139 FLVGLTPMF-GWNMKLTSEYHRNVTFL-SCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAI 196
                +  + G N +   E    +T +  CQ  + +  ++++    L   FIP V M  I
Sbjct: 161 VTYSFSIFYTGANEEGIEELVVALTCVGGCQ--APLNQNWVLLCFLL--FFIPNVAMVFI 216

Query: 197 YLDIFYIIRN---KLSLNLSNSKETGAFY-----GREFKTAKSLFLVLFLFALSWLPLSI 248
           Y  IF + ++   K+    S ++ +   Y      RE K AK+L + +  F +SWLP  +
Sbjct: 217 YSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPY-L 275

Query: 249 INCII--YFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPS 306
           ++ +I  Y N   P  V  + +   + NS MNP++YA+  + F +   LI+   V+   +
Sbjct: 276 VDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVL--RT 333

Query: 307 DSLDTSI 313
           DS  T++
Sbjct: 334 DSSTTNL 340


>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
          Length = 478

 Score = 99.8 bits (247), Expect = 3e-21
 Identities = 83/293 (28%), Positives = 137/293 (46%), Gaps = 16/293 (5%)

Query: 11  ANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAI 70
           A+ T  T+ + +GL  ++GN+ VI     + SL+T    FI++LA++D  +     P+  
Sbjct: 69  AHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFF 128

Query: 71  VVSLGITIHF--YSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIW 128
             SL     F    C F      +F  +S+++L AIA+DRYL +   +    V + RR  
Sbjct: 129 TSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAA 188

Query: 129 LALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFI 188
             L   WL +    L P FGW+  +      + ++    F   +R   M+   F+   F+
Sbjct: 189 FVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFV--FFL 246

Query: 189 PLVVMCAIYLDIFYIIR--NKLSLNLSNSKETGAFYGR------EFKTAKSLFLVLFLFA 240
           PL+++   Y+ IF  IR   +        K  G    +      E K AK + LV+ LF 
Sbjct: 247 PLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFV 306

Query: 241 LSWLPLSIINCIIYFNGEVPQLVLYMG---ILLSHANSMMNPIVYAYKIKKFK 290
           LSW P S +  ++ F G    L  YM     +++ A+++ NPI+YA    K++
Sbjct: 307 LSWAPYSAV-ALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYR 358


>gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo
           sapiens]
          Length = 471

 Score = 99.4 bits (246), Expect = 4e-21
 Identities = 85/317 (26%), Positives = 140/317 (44%), Gaps = 58/317 (18%)

Query: 24  LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMP---LAIVVSLGITIHF 80
           +  I GN+LVI  V L   LQ  T YF++SLA+AD+ +G LVMP   L I+      +  
Sbjct: 86  ILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPS 145

Query: 81  YSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFL 140
             C     L ++F+ ASIM L AI++DRY+ ++  + + R  +  + +L +   W +S  
Sbjct: 146 KLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVG 205

Query: 141 VGL-TPMFGW--NMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIY 197
           + +  P+FG   + K+  E        SC    ++  D  V        FIPL +M   Y
Sbjct: 206 ISMPIPVFGLQDDSKVFKEG-------SC----LLADDNFVLIGSFVSFFIPLTIMVITY 254

Query: 198 LDIFYIIRNKLSLNLSN----------------------------SKETGAFYGR----- 224
                 ++ + +L +S+                             +E G++ GR     
Sbjct: 255 FLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQS 314

Query: 225 ---EFKTAKSLFLVLFLFALSWLPLSIIN-----CIIYFNGEVPQLVLYMGILLSHANSM 276
              E K  K L +V FLF + W P  I N     C    N +V   +L + + + + +S 
Sbjct: 315 ISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSA 374

Query: 277 MNPIVYAYKIKKFKETY 293
           +NP+VY    K ++  +
Sbjct: 375 VNPLVYTLFNKTYRSAF 391


>gi|71999131 opsin 3 [Homo sapiens]
          Length = 402

 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 83/295 (28%), Positives = 132/295 (44%), Gaps = 40/295 (13%)

Query: 22  IGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFY 81
           IGL  +  N+LV+ +      L+T T   +V+++L+D+ V +           G+T  F 
Sbjct: 51  IGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLF----------GVTFTFV 100

Query: 82  SCL-------FMTCLL-----LIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWL 129
           SCL        + C+       +F   SI +L  +A +RY+RV     + RV      W 
Sbjct: 101 SCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVV----HARVINFSWAWR 156

Query: 130 ALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDY----MVYFSFLTW 185
           A+   WL S      P+ GWN      Y  +V  L C  V     D      V F FL  
Sbjct: 157 AITYIWLYSLAWAGAPLLGWN-----RYILDVHGLGCT-VDWKSKDANDSSFVLFLFLGC 210

Query: 186 IFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLP 245
           + +PL V+   Y  I Y IR    +    + +       E K AK  FL++F F + W+P
Sbjct: 211 LVVPLGVIAHCYGHILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMP 270

Query: 246 LSIINCIIYFNGE---VPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLIL 297
             +I C +  NG    V   +  +  L + +N++ NP++Y + I+KF+ + L +L
Sbjct: 271 YIVI-CFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLL 324


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.332    0.142    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,863,338
Number of Sequences: 37866
Number of extensions: 370344
Number of successful extensions: 2898
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 491
Number of HSP's successfully gapped in prelim test: 240
Number of HSP's that attempted gapping in prelim test: 1292
Number of HSP's gapped (non-prelim): 925
length of query: 318
length of database: 18,247,518
effective HSP length: 102
effective length of query: 216
effective length of database: 14,385,186
effective search space: 3107200176
effective search space used: 3107200176
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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