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Search of human proteins with 44890059
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|44890059 involucrin [Homo sapiens]
(585 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|44890059 involucrin [Homo sapiens] 1178 0.0
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 177 3e-44
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 160 3e-39
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 159 7e-39
gi|148746195 trichohyalin [Homo sapiens] 153 4e-37
gi|221139761 zinc finger protein 853 [Homo sapiens] 143 4e-34
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 127 3e-29
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 118 1e-26
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 117 3e-26
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 111 2e-24
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 110 4e-24
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 106 5e-23
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 106 5e-23
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 104 2e-22
gi|21735548 centrosomal protein 2 [Homo sapiens] 104 3e-22
gi|150170670 piccolo isoform 2 [Homo sapiens] 98 2e-20
gi|150378539 piccolo isoform 1 [Homo sapiens] 98 2e-20
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 97 4e-20
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 94 3e-19
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 94 3e-19
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 93 8e-19
gi|31982906 cingulin-like 1 [Homo sapiens] 93 8e-19
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 92 1e-18
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 92 1e-18
gi|219803769 trichoplein [Homo sapiens] 90 5e-18
gi|14150056 trichoplein [Homo sapiens] 90 5e-18
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 90 7e-18
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 90 7e-18
gi|221219020 NYD-SP11 protein [Homo sapiens] 89 1e-17
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 89 1e-17
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 1178 bits (3048), Expect = 0.0
Identities = 585/585 (100%), Positives = 585/585 (100%)
Query: 1 MSQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQE 60
MSQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQE
Sbjct: 1 MSQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQE 60
Query: 61 EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLN 120
EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLN
Sbjct: 61 EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLN 120
Query: 121 KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQE 180
KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQE
Sbjct: 121 KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQE 180
Query: 181 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQE 240
GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQE
Sbjct: 181 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQE 240
Query: 241 GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQE 300
GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQE
Sbjct: 241 GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQE 300
Query: 301 KQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE 360
KQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE
Sbjct: 301 KQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE 360
Query: 361 GQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQV 420
GQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQV
Sbjct: 361 GQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQV 420
Query: 421 EHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQV 480
EHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQV
Sbjct: 421 EHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQV 480
Query: 481 KHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL 540
KHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL
Sbjct: 481 KHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL 540
Query: 541 EQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKHK 585
EQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKHK
Sbjct: 541 EQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKHK 585
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 177 bits (448), Expect = 3e-44
Identities = 157/485 (32%), Positives = 268/485 (55%), Gaps = 82/485 (16%)
Query: 85 QELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ--QLDQELVKRD 142
+EL++++ E EE Q E + +++ ++L ++LE +K L Q Q+ ++ +
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHI----KELKRKLETDKIPLPQEGQVREQEGQVR 62
Query: 143 EQLGMKKEQLLELPEQQEGHLKHLE----QQEGQLKHPE----QQEGQLELPE----QQE 190
EQ G +EQ ++ EQ EG ++ E +QEGQ++ E +QEGQ+ E +QE
Sbjct: 63 EQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
Query: 191 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSE--- 247
GQ+ +QEGQ+ +QEGQ+ +QEGQ+ +QEGQ+ ++QEGQ+ E
Sbjct: 122 GQVR---EQEGQVR---EQEGQVR---EQEGQVR---EQEGQV---REQEGQVREQEGQV 166
Query: 248 -QQEGQLELSE----QQEGQLKHLE----HQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQ 298
+QEGQ+ E +QEGQ++ E QEGQ+ EEQMG+ + EQ + Q + + +
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE--EQMQKQEEQMGE 224
Query: 299 QEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEH 358
QE+Q E+QMG EQ+E K EQ + Q EQ+ +QE Q++ E+Q +
Sbjct: 225 QEEQMRKQEEQMG-----EQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ------MRE 273
Query: 359 QEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQER 418
QE Q+ ++Q Q +Q +Q+ Q + E+E Q++ +QE Q++ +QE Q+ +QE
Sbjct: 274 QEEQMLKQKEQTEQEEQTGEQEEQ---MREQEEQMR---EQEEQMR---EQEEQMREQEE 324
Query: 419 QVEHLEQQVGQLK-HLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQE 477
Q+ E+Q+ + K + EQ+ Q+ E+Q G+ E EQ Q + + ++E+Q+ E+Q
Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE--EQMQKQEEQVRKQEEQMRKQEEQ- 381
Query: 478 GQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQK 537
+ KQE Q+ E+Q+G EQ+E+ E EQ Q + + +Q+ Q++ E+
Sbjct: 382 -----MRKQEEQMRKQEEQMG-----EQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
Query: 538 GQLEQ 542
G+ ++
Sbjct: 432 GEQKE 436
Score = 176 bits (445), Expect = 7e-44
Identities = 159/467 (34%), Positives = 266/467 (56%), Gaps = 84/467 (17%)
Query: 120 NKQLEEEKKLLDQQLDQ-ELVKRDEQLGMK----KEQLLELPEQQEGHLKHLEQQEGQLK 174
N++L+E+ L ++L E K + QL +K K + ++P QEG ++ +QEGQ++
Sbjct: 6 NEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVR---EQEGQVR 62
Query: 175 HPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLE 234
+QEGQ+ +QEGQ+ +QEGQ+ +QEGQ+ +QEGQ+ +QEGQ+
Sbjct: 63 ---EQEGQVR---EQEGQVR---EQEGQVR---EQEGQVR---EQEGQVR---EQEGQV- 103
Query: 235 LPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLK 294
++QEGQ+ +QEGQ+ +QEGQ++ QEGQ+ EQ GQ++ +QEGQ++
Sbjct: 104 --REQEGQVR---EQEGQVR---EQEGQVRE---QEGQVR---EQEGQVR---EQEGQVR 146
Query: 295 HLDQQEKQPE-LPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQL 353
+ Q ++ E +Q GQ++ +QEGQ + +QEGQ+ EQEGQ++ +QEGQ
Sbjct: 147 EQEGQVREQEGQVREQEGQVR---EQEGQ---VREQEGQVR---EQEGQVR---EQEGQ- 193
Query: 354 EHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQL 413
+ QEGQ+G E+Q+ + Q E+ Q Q + + E+E Q++ +Q G +QE Q+
Sbjct: 194 --MGEQEGQMGEQEEQMGE--QEEQMQKQEEQMGEQEEQMRKQEEQMG------EQEEQV 243
Query: 414 EQQERQVEHLEQQV-GQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLEL 472
++QE QV+ E+Q+ Q + + EQE Q++ EQ++ L+ EQ + + EQEE+ E
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMR--EQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
Query: 473 PEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKD 532
EQ Q + + +QE Q+ E+Q+G +Q+E+ E EQ Q + + +QE Q+ +
Sbjct: 302 EEQMREQEEQMREQEEQMREQEEQMG-----KQEEQMWEQKEQMWEQKEQMWKQEEQMGE 356
Query: 533 LEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQ 579
E+Q + E+ QV+ + + + E + E Q +KQE Q
Sbjct: 357 QEEQMQKQEE--------QVRKQEEQMRKQEEQMRKQEEQMRKQEEQ 395
Score = 154 bits (388), Expect = 3e-37
Identities = 143/472 (30%), Positives = 245/472 (51%), Gaps = 68/472 (14%)
Query: 18 ELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKG-LPEQECE 76
+L++T + H +++K+ K+P LP E +++E + +G + EQE +
Sbjct: 21 QLVETEKSEIQLHIKELKRKLET----DKIP--LPQEGQVREQEGQVREQEGQVREQEGQ 74
Query: 77 QQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQ 136
+++E Q +E + Q EQ + ++ E ++ + + +++ Q+ +Q + ++ Q +Q
Sbjct: 75 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 134
Query: 137 ELVKRDEQLGMKKEQLLELPEQQEGHLKHLE----QQEGQLKHPE----QQEGQLELPEQ 188
E R EQ G +EQ ++ EQ EG ++ E +QEGQ++ E +QEGQ+ +
Sbjct: 135 EGQVR-EQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQVR---E 189
Query: 189 QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQ 248
QEGQ+ +QEGQ+ E+Q G +QE Q++ E+Q G +QE Q+ E+
Sbjct: 190 QEGQM---GEQEGQMGEQEEQMG------EQEEQMQKQEEQMG------EQEEQMRKQEE 234
Query: 249 QEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQ 308
Q G+ E EQ + Q + ++ QE Q+ EEQM +Q+E+ E EQ
Sbjct: 235 QMGEQE--EQVQKQEEQVQKQEEQMRKQEEQM---------------REQEEQMREQEEQ 277
Query: 309 QMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQ 368
+ Q + EQ+E + EQ Q EQ+ EQE Q++ E+Q + QE Q+G E+
Sbjct: 278 MLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ------MREQEEQMGKQEE 331
Query: 369 QVLQLK-QLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQV 427
Q+ + K Q+ +Q+ Q EE+ G+ Q+E K Q Q EQ +Q E + +Q
Sbjct: 332 QMWEQKEQMWEQKEQMWKQEEQMGE-----QEEQMQKQEEQVRKQEEQMRKQEEQMRKQE 386
Query: 428 GQLKHLEEQEGQLK-HLEQQQGQLEVPEQQVGQPKNLEQEEKQLE-LPEQQE 477
Q++ EEQ G+ K + +Q+ Q+ E+Q+G+ K EQ KQ E + EQ+E
Sbjct: 387 EQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK--EQMRKQEEHMGEQKE 436
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 160 bits (405), Expect = 3e-39
Identities = 147/540 (27%), Positives = 277/540 (51%), Gaps = 36/540 (6%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLK-QEKTQRD 116
+QEE+ K + +QE ++ QE+ L++Q + E+ +K E++L+ QEK R+
Sbjct: 238 RQEEELREQEKKIRKQE---EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE 294
Query: 117 QQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHP 176
Q+ K+L E+KKL +Q+ +++ +++E++ ++E++ E E+ + L +QE Q++
Sbjct: 295 QE--KELREQKKLREQE--EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
Query: 177 EQ--QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE---G 231
EQ ++ + + EQ E E E+ Q ++ EQ+E E +E + ++ E++E
Sbjct: 351 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410
Query: 232 QLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEG 291
Q E Q+QE + E++E Q + +Q+ +L E + Q E EQ +++ E+ G
Sbjct: 411 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 470
Query: 292 QLKHLDQQEKQPELPEQQMGQLKHLEQQE----GQPKHLEQQEGQLEQLEEQEGQLKHLE 347
Q K + +QEK E +Q Q + + QE Q + + +Q+ +L + EE+ + K +
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530
Query: 348 QQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQ--QEGQLKH 405
QQE ++ + + Q Q ++++ E+ + + K + EEE ++ + QE + K
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 406 LVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQ-QVGQPKNLE 464
Q+E EQ+E+ E E+ Q + + EQE + K EQ++ E E+ Q + K E
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 465 QEEKQLELPEQQEGQVKHLEKQEAQL-ELPEQQVGQPKHL-EQQEKHLEHPEQQDGQLKH 522
QEEK E E+ Q + ++ QE ++ E E+ GQ + + EQ+EK E+ GQ +
Sbjct: 651 QEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Query: 523 LEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPP 582
+ QE ++ E+ + + E+ Q + +Q LP EH+++ E PP
Sbjct: 711 MWGQEEKMWGQEEMREKEER-----IRDQKEKMQERLP---------EHEERCSEPCLPP 756
Score = 158 bits (399), Expect = 1e-38
Identities = 138/545 (25%), Positives = 286/545 (52%), Gaps = 41/545 (7%)
Query: 28 NTHQEQM-KQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEP---- 82
NT QE+M +Q L +K+ KQEEK + L EQE + +++E
Sbjct: 230 NTLQEEMWRQEEELREQEKKI---------RKQEEKMWRQEERLREQEGKMREQEEKMRR 280
Query: 83 QEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRD 142
QE+ L++Q E E+ +K +++L++++ Q +Q K E+E+K+ +Q+ +++ +++
Sbjct: 281 QEKRLREQEKELREQ-EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE--EKMWRQE 337
Query: 143 EQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQ-QEG 201
E+L +++Q+ E ++ + + +Q+ +L+ E++ + E +QE +++ E+ +E
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 202 QLELPEQQEGQLELPE----QQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSE 257
+ ++ E++E E E Q+E E E++ Q LP+Q+E E + QE + ++ E
Sbjct: 398 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 457
Query: 258 QQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQL-----KHLDQQEKQPELPEQQMGQ 312
Q+E +++ E GQ E++M + + + +QE Q+ K DQ++K + E+ Q
Sbjct: 458 QEE-KIRDQEEMWGQ----EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQ 512
Query: 313 LKHLEQQEG----QPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQ 368
+ L ++E Q K +Q+E E+ + QE + K +Q+E E +E + + E+
Sbjct: 513 DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
Query: 369 QVLQLKQLEKQQGQPKHLEEEEGQL--KHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQ 426
+ + +Q EK Q Q + + E+E ++ + QE + K Q+E EQ+E +++
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632
Query: 427 VGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLE-QEEKQLELPEQQEGQVKHLEK 485
+ + + QE + K EQ++ E E+ Q + ++ QEEK E E+ +GQ + + +
Sbjct: 633 MMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692
Query: 486 QEAQLELPEQQV-GQPKHL-EQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQP 543
QE ++ E+++ GQ + + Q+EK E ++ + + +Q+E + L + + + +P
Sbjct: 693 QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752
Query: 544 VFAPA 548
P+
Sbjct: 753 CLPPS 757
Score = 130 bits (326), Expect = 4e-30
Identities = 122/501 (24%), Positives = 255/501 (50%), Gaps = 38/501 (7%)
Query: 70 LPEQECEQQQK----EPQEQELQQQHWEQHEEYQKAEN--PEQQ---LKQEKTQRDQQLN 120
L ++ E Q+K E ++ E+Q E + ++A+ P+ Q L++E +++++L
Sbjct: 185 LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
Query: 121 KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ- 179
E+EKK+ Q+ +++ +++E+L ++ ++ E E+ K L +QE +L+ E++
Sbjct: 245 ---EQEKKIRKQE--EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 180 -------EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ--EGQLELPEQQE 230
E + ++ EQ+E E E+ Q E +QE +L E+Q E + ++ +Q+E
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 231 GQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQE 290
E ++ + E +QE E E+ + + + E ++ E E Q + +++QE
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Query: 291 GQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQE 350
+ +++E Q + +Q +L E+ + Q + + +QE ++ EE GQ K + +QE
Sbjct: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
Query: 351 GQLEHLEHQ-EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQL---KHLVQQEGQLKHL 406
E + E + + +Q+ Q E+ Q + L E+E ++ K + QQE +++
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR-- 537
Query: 407 VQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQE 466
+E + ++QE++ E+++ + + + E+E +++ E+ + E + Q + K EQE
Sbjct: 538 --EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKMQEQEEKMREQE 594
Query: 467 EKQLE----LPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKH 522
EK E + EQ+E + EK Q E + Q + EQ+EK E E+ Q +
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 523 LEQQEGQLKDLEQQ-KGQLEQ 542
+ +QE ++++ E++ +GQ E+
Sbjct: 655 MREQEEKMREQEEKMQGQEEK 675
Score = 128 bits (321), Expect = 2e-29
Identities = 113/479 (23%), Positives = 245/479 (51%), Gaps = 31/479 (6%)
Query: 85 QELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ----QLDQELVK 140
+EL++++ E E+ + AE+ + +++ ++L ++LE K LL Q L +E+ +
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNV----KELKRKLERAKFLLPQVQTNTLQEEMWR 238
Query: 141 RDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQE 200
++E+L +++++ + E+ + L +QEG+++ E++ + E +E + EL EQ++
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE-KRLREQEKELREQEK 297
Query: 201 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQE 260
E + +E + ++ EQ+E E E+ Q E +QE +L EQ++ E ++
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW--EQEKQMREQEQKMR 355
Query: 261 GQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKH----LDQQEKQPELPEQQMGQLKHL 316
Q + + Q+ +L EE+M + + + +QE +++ ++++K E E Q + +
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 317 EQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQL 376
++QE E++E Q ++L EQ+ +L E+ + Q E + QE ++ E+ Q K++
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
Query: 377 EKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQ 436
+Q+ K E+E+ + + Q + + QE ++ +Q+ ++ E+++ + K + +Q
Sbjct: 476 WRQE---KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532
Query: 437 EGQL----KHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLEL 492
E ++ K EQ++ + E+ + + E+E+K E E Q + +++QE ++
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 493 PEQ---------QVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQ 542
E+ Q + K EQ+EK E E+ Q + E + K EQ++ EQ
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ 651
Score = 119 bits (297), Expect = 1e-26
Identities = 123/511 (24%), Positives = 248/511 (48%), Gaps = 33/511 (6%)
Query: 98 YQKAENPEQQLKQEKTQRDQQL--NKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLEL 155
++KA+ ++L +E+ +L N EE K + +L ++L + + + + EL
Sbjct: 154 HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL 213
Query: 156 PEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL 215
+ E L Q + E + EL EQ++ + E+ Q E +QEG++
Sbjct: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 273
Query: 216 PEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEV 275
E++ + E +E + EL +Q++ EL EQ++ + + + QE + K E +E E
Sbjct: 274 QEEKMRRQE-KRLREQEKELREQEK---ELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 329
Query: 276 PEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQ----LKHLEQQEGQPKHLEQQEG 331
E+ Q + L +QE Q++ +QE++ E++M + L+ E++ + + + +QE
Sbjct: 330 EEKMWRQEERLWEQEKQMR---EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE 386
Query: 332 QL---EQLEEQEGQLKHLE------------QQEGQLEHLEHQEGQLGLPEQQVLQLKQL 376
++ E++ E+E +++ E Q+E E E + Q LPEQ+ +L +
Sbjct: 387 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE-KLWEQ 445
Query: 377 EKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQ 436
EK Q Q + + E+E +++ + GQ K + +QE EQ+++ E E+ Q + + +Q
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 437 EGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQ 496
E ++ EQ + E E+ Q K +QEEK E + QE + K +++E E +
Sbjct: 506 EERM--WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 497 VGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQ-VQDI 555
+ K E++E E E+ Q + + +QE ++ + E++ + E+ ++ Q+
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
Query: 556 QPALPTKGEVLLPVEHQQQKQEVQ-WPPKHK 585
+ + + E++ E + Q+QE + W + K
Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Score = 95.1 bits (235), Expect = 2e-19
Identities = 90/348 (25%), Positives = 180/348 (51%), Gaps = 45/348 (12%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENP---------EQQL 108
+QEEK + LPEQ+ E+ ++ + QE +++ WEQ E+ + E ++++
Sbjct: 424 EQEEKEWQQQR-LPEQK-EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
Query: 109 KQEKTQRDQQLNKQLEEEKKLLDQQ-----LDQELVKRDEQLGMKK------EQLLELPE 157
++++ Q +Q K ++E+K+ DQ+ D+ L +++E++ +K E++ E +
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKK 541
Query: 158 QQEGHLKHLEQQEGQLKHPEQQEGQLELPEQ-----------QEGQLELPEQQEGQLELP 206
QE K +Q+E + +E + ++ E+ QE + ++ EQ+E ++
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE---KMW 598
Query: 207 EQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHL 266
EQ+E E E+ Q E +QE + ++ +Q+E E E+ + Q E +QE +++
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-- 656
Query: 267 EHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHL 326
E +E E E+ GQ + + +QE +++ Q+EK E E+ GQ + + QE +
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQ--GQEEKMREQEEKMRGQEEKMWGQEEKMWGQ 714
Query: 327 EQQEGQLEQLEEQEGQLKHLEQQEGQLEHL-EHQE--GQLGLPEQQVL 371
E++ E++ E+E +++ +Q+E E L EH+E + LP +VL
Sbjct: 715 EEKMWGQEEMREKEERIR--DQKEKMQERLPEHEERCSEPCLPPSKVL 760
Score = 82.0 bits (201), Expect = 1e-15
Identities = 113/489 (23%), Positives = 226/489 (46%), Gaps = 42/489 (8%)
Query: 104 PEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLE--LPEQQEG 161
P + EKT++ NK E +KK D + KK+++ PE
Sbjct: 8 PPHPMMSEKTRQ----NKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTS 63
Query: 162 HLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLE--LPEQQEGQLELPEQQ 219
H + E + H Q+ + E+ E Q+ + + Q+ +LE L Q+ + +
Sbjct: 64 EGCHSPEDEKKASHQHQEALRREI-EAQDHTIRILTCQKTELETALYYSQDAARKF---E 119
Query: 220 EGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQ 279
+G L + G+L G+L Q +S + +++E + + +
Sbjct: 120 DGNLGESKDLAGRLHHSWHFAGEL-----QRALSAVSTWHKKADRYIEELTKERDALSLE 174
Query: 280 MGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQ 339
+ + + +E + K+ + QEK L E + +++ L +E + K LE+ + L Q++
Sbjct: 175 LYR-NTITNEELKKKNAELQEKL-RLAESEKSEIQ-LNVKELKRK-LERAKFLLPQVQTN 230
Query: 340 EGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVL-QLKQLEKQQGQPKHLEEE-EGQLKHLV 397
Q E+ Q E L QE ++ E+++ Q ++L +Q+G+ + EE+ Q K L
Sbjct: 231 TLQ----EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR 286
Query: 398 QQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQV 457
+QE K L +QE +L +Q++ E EQ QE + K EQ++ E E+
Sbjct: 287 EQE---KELREQEKELREQKKLREQEEQM---------QEQEEKMWEQEEKMREQEEKMW 334
Query: 458 GQPKNLEQEEKQLELPEQQ-EGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQ 516
Q + L ++EKQ+ EQ+ Q + + +Q+ +L E+++ + + + +QE+ ++ E+
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Query: 517 DGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQ 576
+ K + ++E +++ E++ + E+ ++ + Q Q LP + E L E Q+++
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ--QQRLPEQKEKLWEQEKMQEQE 452
Query: 577 EVQWPPKHK 585
E W + K
Sbjct: 453 EKIWEQEEK 461
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 159 bits (402), Expect = 7e-39
Identities = 139/509 (27%), Positives = 268/509 (52%), Gaps = 34/509 (6%)
Query: 58 KQEEKHMTAVKGLPEQECE--QQQKEPQEQ-ELQQQHWEQHEEYQKAENPEQQLKQEKTQ 114
+QEEK K L EQE E +Q+KE +EQ EL++Q + E+ +K E+++++++ +
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Query: 115 RDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLK 174
+Q + E+EK++ +Q+ Q++ ++E++ + E+L E E+ K EQ E +
Sbjct: 371 MWRQEERLWEQEKQMREQE--QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMRE 428
Query: 175 HPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPE----QQEGQLELPEQQE 230
+ QE + + +Q+E E +E + ++ E++E E E Q+E E E++
Sbjct: 429 EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 488
Query: 231 GQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQE 290
Q LP+Q+E E + QE + ++ EQ+E +++ E GQ E++M + + + +QE
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEE-KIRDQEEMWGQ----EKKMWRQEKMREQE 543
Query: 291 GQLKHLDQQEKQPELPEQQMGQLKHLEQ--QEGQPKHLEQQEGQLEQLEEQEGQLKHLEQ 348
Q+ +Q+EK + ++ Q + +E+ QE + K +Q+E E+ +E + K E+
Sbjct: 544 DQM--WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 349 QEGQLEHLEH-QEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLV 407
+E E E QE + + EQ+ +Q EK Q Q + + E+E ++ ++ + + L
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 408 QQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQ-----QGQLEVPEQQVGQPKN 462
+Q+ +L + E+ E + Q + K E+++ + K EQ+ Q ++ E + K
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKK 721
Query: 463 L--------EQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHL-EQQEKHLEHP 513
+ EQEEK E E+ + Q + + +QE ++ E+++ + + L EQ+EK EH
Sbjct: 722 MREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 781
Query: 514 EQQDGQLKHLEQQEGQLKDLEQQKGQLEQ 542
+ Q+ Q K EQ+E E+ +GQ E+
Sbjct: 782 KMQE-QEKIWEQEEKMRDQEEKMRGQEEK 809
Score = 154 bits (389), Expect = 2e-37
Identities = 149/535 (27%), Positives = 268/535 (50%), Gaps = 41/535 (7%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAEN--PEQQLKQEKTQR 115
+QEEK + L EQE + +++E + ++ +++ WEQ E ++ E EQ+ E+ ++
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425
Query: 116 DQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKH 175
++ K E+EKK DQ +E ++ +E++ +++++ E E + +++QE +
Sbjct: 426 MREEKKMQEQEKKTRDQ---EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 176 PEQQEGQLE-LPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLE 234
E++E Q + LPEQ+E E + QE + ++ EQ+E ++ E+ GQ + +QE E
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE-KIRDQEEMWGQEKKMWRQEKMRE 541
Query: 235 LPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLK 294
Q Q E QE ++ +Q+E K + QE + EE+M + + + ++E +++
Sbjct: 542 QEDQMWEQEEKMRDQE--QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599
Query: 295 HLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEE-QEGQLKHLEQQEGQL 353
E++M + + + QE + K EQ+E EQ E+ QE + K EQ+E
Sbjct: 600 E-----------EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMW 648
Query: 354 EHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQL 413
E E Q LPEQ+ +L + EK Q Q K E+EE + +QE K +QE +
Sbjct: 649 EQEEKMWEQQRLPEQKE-KLWEHEKMQEQEKMQEQEE----KIWEQEKMEKKTQEQEKKT 703
Query: 414 EQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQ-----VGQPKNLEQEEK 468
QE+ E + + K EE+E + E+ Q Q E ++Q + K EQEEK
Sbjct: 704 WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Query: 469 ---QLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQ 525
Q LPEQ+E +H EK + Q ++ EQ + K +Q+EK E+ GQ + +
Sbjct: 764 MWEQQRLPEQKEKLWEH-EKMQEQEKIWEQ---EEKMRDQEEKMRGQEEKMRGQEEKMRG 819
Query: 526 QEGQLKDLEQQKGQLEQPVFAPAP---GQVQDIQPALPTKGEVLLPVEHQQQKQE 577
QE ++ E++ E+ ++ GQ + ++ + + E + E + + QE
Sbjct: 820 QEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQE 874
Score = 153 bits (387), Expect = 4e-37
Identities = 143/571 (25%), Positives = 286/571 (50%), Gaps = 56/571 (9%)
Query: 28 NTHQEQM-KQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEP---- 82
NT QE+M +Q L +K+ KQEEK + L EQE + +++E
Sbjct: 268 NTLQEEMWRQEEELREQEKKI---------RKQEEKMWRQEERLREQEGKMREQEEKMWR 318
Query: 83 QEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRD 142
QE+ L++Q E E+ +K +++L++++ Q +Q K E+E+K+ +Q+ +++ +++
Sbjct: 319 QEKRLREQEKELREQ-EKELREQKELREQEEQMQEQEEKMWEQEEKMREQE--EKMWRQE 375
Query: 143 EQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQ----QEGQLELPEQQEGQLELPEQ 198
E+L +++Q+ E ++ + + +Q+ +L+ E+ QE E E+ + ++ EQ
Sbjct: 376 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQ 435
Query: 199 QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQ 258
++ + E+ + + + E+++ E E Q E Q+QE + E++E Q + +
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
Query: 259 QEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQ 318
Q+ +L E + Q E EQ +++ E+ GQ K + +QEK E +Q Q + +
Sbjct: 496 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 555
Query: 319 QEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEK 378
QE K +Q+E ++ +EQE K +Q+E E +E + + E++ + +Q EK
Sbjct: 556 QE--QKMWDQEERMEKKTQEQEK--KTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611
Query: 379 QQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEG 438
Q Q + ++E+E + + +QE ++++QE E + +Q ++ EE+
Sbjct: 612 MQEQEEKMQEQE-------------EKMWEQEEKMQEQE---EKMWEQEEKMWEQEEKMW 655
Query: 439 QLKHLEQQQGQLEVPEQQVGQPKNLEQEEK---QLELPEQQEGQVKHLEKQEAQLELPEQ 495
+ + L +Q+ +L E+ Q K EQEEK Q ++ ++ + Q K QE E
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 496 QVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDI 555
+ + K E++E E E+ Q + +++QE ++ + E++ + E+ ++
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE--------- 766
Query: 556 QPALPTKGEVLLPVEHQQ-QKQEVQWPPKHK 585
Q LP + E L EH++ Q+QE W + K
Sbjct: 767 QQRLPEQKEKLW--EHEKMQEQEKIWEQEEK 795
Score = 133 bits (335), Expect = 4e-31
Identities = 135/540 (25%), Positives = 274/540 (50%), Gaps = 54/540 (10%)
Query: 70 LPEQECEQQQKEP----QEQELQQQHWEQHEEYQKAEN--PEQQ---LKQEKTQRDQQLN 120
L ++ E Q+K P ++ E+Q E + ++A+ P+ Q L++E +++++L
Sbjct: 223 LKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 282
Query: 121 KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQE 180
E+EKK+ Q+ +++ +++E+L ++ ++ E E+ K L +QE +L+ E+
Sbjct: 283 ---EQEKKIRKQE--EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK-- 335
Query: 181 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL--ELPQQ 238
EL EQ+ EL EQ+E ++ EQ+E E E+ Q E +QE +L + Q
Sbjct: 336 ---ELREQK----ELREQEE---QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 385
Query: 239 QEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQ 298
+E + ++ +Q+E E E+ + + + QE E E+ + K EQ++ K DQ
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK---KTRDQ 442
Query: 299 QEKQPE---LPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQL-- 353
+EK E + E++ + E Q + +++QE + + EE+E Q + L +Q+ +L
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 354 -EHLEHQEGQLGLPEQQVLQLKQL---EKQQGQPKHLEEEEGQL-----KHLVQQEGQLK 404
E ++ QE ++ E+++ +++ EK+ + + + E+E Q+ K Q++
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562
Query: 405 HLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLE 464
+ E + ++QE++ E+++ + + + E+E +++ E+ + E + Q + K E
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKMQEQEEKMQE 621
Query: 465 QEEKQLELPEQ-QEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQL--- 520
QEEK E E+ QE + K E++E E E+ Q + EQ+EK EH + Q+ +
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681
Query: 521 ---KHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQE 577
K EQ++ + K EQ+K +Q +++ + + + E++ E + Q+QE
Sbjct: 682 QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE-SMREREKKMREEEEMMREQEEKMQEQE 740
Score = 133 bits (334), Expect = 5e-31
Identities = 128/488 (26%), Positives = 255/488 (52%), Gaps = 49/488 (10%)
Query: 85 QELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ----QLDQELVK 140
+EL++++ E E+ AE+ + +++ ++L ++LE K LL Q L +E+ +
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNV----KELKRKLERAKFLLPQVQTNTLQEEMWR 276
Query: 141 RDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQE 200
++E+L +++++ + E+ + L +QEG+++ E++ + E +E + EL EQ++
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQE-KRLREQEKELREQEK 335
Query: 201 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQE 260
E E +E + ++ EQ+E E E+ Q E +QE +L EQ++ E ++
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW--EQEKQMREQEQKMR 393
Query: 261 GQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQL---KHLDQQEKQPELPEQQMGQLKHLE 317
Q + + Q+ +L EE+M + + + +Q ++ K + +QEK+ E++M + + +
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 318 QQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLE 377
++E K + ++E E + EQE +++ +Q+E E E + Q LPEQ+ +L + E
Sbjct: 454 ERE---KKMREEE---ETMREQEEKMQ--KQEENMWEQEEKEWQQQRLPEQKE-KLWEQE 504
Query: 378 KQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQE 437
K Q Q + + E+E +++ + GQ K + +QE EQ+++ E E+ Q + + +QE
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564
Query: 438 GQLKHLEQQQGQ--------------LEVPEQQVGQPKNL--EQEEKQLE----LPEQQE 477
+++ Q+Q + + E+++ + + + EQEEK E + EQ+E
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624
Query: 478 GQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEH---PEQQDGQLKHLEQQEGQLKDLE 534
+ EK + Q E +Q + K EQ+EK E PEQ++ +H + QE Q K E
Sbjct: 625 KMWEQEEKMQEQEEKMWEQ--EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-QEKMQE 681
Query: 535 QQKGQLEQ 542
Q++ EQ
Sbjct: 682 QEEKIWEQ 689
Score = 131 bits (329), Expect = 2e-30
Identities = 126/464 (27%), Positives = 236/464 (50%), Gaps = 35/464 (7%)
Query: 54 EVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHE-EYQKAENPEQQLK--- 109
E ++EE+ K + E+E +++E + Q+ ++ WEQ E E+Q+ PEQ+ K
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 110 QEKTQRDQQLNKQLEEEKKLLDQQL---DQELVKRDEQLGMKKEQLLELPEQQEGHLKHL 166
QEK Q ++ K E+E+K+ DQ+ ++ + R E++ +++Q+ E E+ + +
Sbjct: 503 QEKMQEQEE--KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 167 EQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ-QEGQLEL 225
QE +++ + QE + + +Q+E E +E + ++ E++E E E+ QE + ++
Sbjct: 561 WDQEERMEK-KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 619
Query: 226 PEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKY 285
EQ+E E ++ + Q E +QE ++ E++ + + L Q+ +L E+ Q K
Sbjct: 620 QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679
Query: 286 LEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQ---EGQPKHLEQQE---GQLEQLEEQ 339
EQ+E + ++K E ++ Q K E++ E + K E++E Q E+++EQ
Sbjct: 680 QEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ 739
Query: 340 EGQLKH-----LEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLK 394
E +++ EQ+E E E Q LPEQ+ +L + EK Q Q K E+EE
Sbjct: 740 EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE-KLWEHEKMQEQEKIWEQEEKMRD 798
Query: 395 HLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQV-GQLKHLEEQEGQLKHLEQQQGQLEVP 453
+ GQ + + QE ++ QE ++ E+++ GQ + + QE E+ GQ E
Sbjct: 799 QEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE------EKMWGQEEKM 852
Query: 454 EQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQV 497
E+ K QEEK E E+ GQ + + +QE ++ E+++
Sbjct: 853 EE-----KMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 54.3 bits (129), Expect = 3e-07
Identities = 48/194 (24%), Positives = 96/194 (49%), Gaps = 24/194 (12%)
Query: 31 QEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQ 90
QE+M++ + +K+ E E+ +QEEK + + EQE E ++E + E +++
Sbjct: 706 QEKMREEESMREREKKMREE--EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Query: 91 HWEQHE---------EYQKAENPEQQLKQEKTQRDQ------QLNKQLEEEKKLLDQQLD 135
WEQ E++K + E+ +QE+ RDQ Q K +E+K+ Q +
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQ--E 821
Query: 136 QELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLEL 195
+++ ++E++ ++E++ E+ G + +E+ K Q+E E E+ GQ E
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEE-----KMQGQEEKMREQEEKMRGQEEK 876
Query: 196 PEQQEGQLELPEQQ 209
+QE ++ E++
Sbjct: 877 MREQEEKMRGQEEK 890
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 153 bits (387), Expect = 4e-37
Identities = 132/510 (25%), Positives = 269/510 (52%), Gaps = 45/510 (8%)
Query: 58 KQEEKHMTAVKGLPEQE-CEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQE----- 111
+ EE+ + LPE+E EQ++++ +E+E + Q E+ E+ Q+ E +Q ++E
Sbjct: 799 RAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE 858
Query: 112 --------KTQRDQQLNKQLEEEKK-----LLDQQLDQELVKRDEQLGMKKEQLLELPEQ 158
+ +RDQ+ QLEEE+K L + QE +++++QL ++E+ L+ E+
Sbjct: 859 DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREER 918
Query: 159 QEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ 218
++ + E+Q + + +Q+E QL E+++ + + E+Q + + +Q+E QL E
Sbjct: 919 EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP 978
Query: 219 QEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEE 278
++ + + E++ + E QQ+E QL E+++ + + E+Q + L+ +E QL E
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Query: 279 QMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEE 338
+ +L+ E+Q + + L Q+E+Q E++ + + LE+Q + + L+Q+E QL + E
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 339 QEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQ 398
++ + + E+Q + E L+ +E QL E++ + ++LE+Q + + +++EE QL
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL---- 1154
Query: 399 QEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVG 458
+ E ++R+ + LE+Q + + L+++E QL EQ++ + E Q
Sbjct: 1155 -------------REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Query: 459 QPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDG 518
+ + Q+ KQ E Q +K + E + + + +V +Q + LE + +D
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR 1261
Query: 519 Q----LKHL--EQQEGQLKDLEQQKGQLEQ 542
Q L+HL EQQE +D EQ++ + +Q
Sbjct: 1262 QSQQDLQHLLGEQQE---RDREQERRRWQQ 1288
Score = 152 bits (384), Expect = 8e-37
Identities = 141/502 (28%), Positives = 274/502 (54%), Gaps = 42/502 (8%)
Query: 50 ELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQE---QELQQQHWEQHEEYQKAENPEQ 106
E P E ++ E KG +E +QQ++E Q+ QE +++ W + E + E E+
Sbjct: 203 EFPDEEQLRRRELLELRRKG--REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE--EE 258
Query: 107 QLKQEKTQRDQQLNKQLEEEKKLLDQQL---------DQELVKRDEQLGMKKEQLLELPE 157
+L++E+ QR ++L ++ E+ +KL Q+L Q+ ++R++QL K+E+ E E
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE--ERRE 316
Query: 158 QQEGHLKHLEQQEGQLKHPEQQ--EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL 215
QQE + E++E Q + EQQ Q E EQQ + + E++E QL EQ+E + E
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR-REQEEERREQ 375
Query: 216 PEQQEGQLELPEQ--QEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQL 273
++E QL +Q +E QL QQ + +L +Q+ + E ++E QL+ + +E
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Query: 274 EVPEEQMGQLKYLEQQEGQLKHLDQQEK-QPELPEQQMGQLKHLEQQEGQPKHLE-QQEG 331
+ E++ + + +QE + L ++E+ + E++ QLK +++E + + L+ ++E
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE 495
Query: 332 QLEQLEEQEGQLKHLEQQEGQLEHLEHQEG----QLGLPEQQVLQLKQLEKQQ-----GQ 382
+ EQ E +E QL+ EQ+E + + L+ QE Q L +Q L+ +Q E+++ +
Sbjct: 496 RREQQERREQQLRR-EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 383 PKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQ---ERQVEHLEQQV--GQLKHLEEQE 437
K LE+E + + +QE + L+++E + QQ Q E LEQ++ +++ LE++E
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE 614
Query: 438 GQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQV 497
+ + L++++ + E +Q + + E+ ++QL EQQE + + L+++E + L EQ++
Sbjct: 615 RREQRLKREEPEEERRQQLLKSEEQEERRQQQLR-REQQERREQRLKREEEEERL-EQRL 672
Query: 498 GQPKHLEQQEKHLEHPEQQDGQ 519
+ E++E+ L EQ+ +
Sbjct: 673 KREHEEERREQELAEEEQEQAR 694
Score = 152 bits (383), Expect = 1e-36
Identities = 141/523 (26%), Positives = 280/523 (53%), Gaps = 60/523 (11%)
Query: 72 EQECEQQQKEPQEQELQQQHWEQHEEYQK-------AENPEQQLKQEKTQRDQQLNKQLE 124
EQ ++++++ EQE ++Q ++ +E ++ E +Q+LK+E+ +R +Q K+ E
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR-E 605
Query: 125 EEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHL-----EQQEGQLKHPEQQ 179
E ++L ++ ++ +KR+E +++QLL+ EQ+E + L E++E +LK E++
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 180 EGQLELPEQQEGQLELPEQQEGQLELPEQQEG-QLELPE-QQEGQLELPEQQEGQLELPQ 237
E +LE ++E + E EQ+ + E + +E + +P+ Q + + E +Q P+
Sbjct: 666 E-RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 238 QQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLD 297
+QEGQ EQ+E + + + Q + H++ Q EEQ + Q E + +
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ---EEEQRRDFTWQWQAEEKSERGR 781
Query: 298 QQ-EKQPELPEQQMGQLKHLEQQEGQPKHL---EQQEGQLEQLEEQEGQLKHLEQQEGQL 353
Q+ +P L EQ+ QL+ E+Q+ + + L E++E + Q E+E +L+ LE++E QL
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE-QL 840
Query: 354 EHLEH----QEGQLGLPEQQVLQLKQLEKQQGQPK-HLEEEEGQLKHLVQQEGQLKHLVQ 408
+ E QE + GL E Q + Q +++ + + LEEE + +H + + L+ ++
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
Query: 409 QEGQL-----------EQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQV 457
+E QL E+++R+ + E+Q + + L+++E QL E+++ + + E+Q
Sbjct: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Query: 458 GQPKNLEQEEKQL--ELPE---QQEGQVKHLEKQEAQLELP---------------EQQV 497
+ K L+Q+E+QL E PE +QE + K+ E++E Q E E+Q
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 498 GQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL 540
+ L+Q+E+ L E++ +L+ E+Q + ++L+Q++ QL
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL 1063
Score = 151 bits (381), Expect = 2e-36
Identities = 150/517 (29%), Positives = 271/517 (52%), Gaps = 51/517 (9%)
Query: 72 EQECEQQQKEPQEQELQQQHW---EQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKK 128
EQE +QQ + ++E +++ W E+ E ++ E EQQL++E+ +R +Q K+ EEE++
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 129 LL-----DQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKH-LEQQEGQLKHPEQQEGQ 182
L +QQL +E +R EQL ++E+ E++E LK E++ QL E++ Q
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587
Query: 183 LELPEQQEGQLE--LPEQQEGQLELPEQQEGQL--ELPEQQEGQLELPEQQEGQLELPQQ 238
L +QE +LE L ++ +LE E++E +L E PE++ Q L +++ + Q
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL 647
Query: 239 QEGQLELSEQQEGQLELSEQQEGQLKHLEHQEG--QLEVPEEQMGQLKYLEQQEGQLKHL 296
+ Q E EQ+ + E E+ E +LK EH+E + E+ EE+ Q + E+ + ++
Sbjct: 648 RREQQERREQRLKREEEEERLEQRLKR-EHEEERREQELAEEEQEQAR--ERIKSRIPKW 704
Query: 297 DQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLE---QLEEQEGQLKHLEQQEGQL 353
Q + + E +Q +QEGQ + EQ+E + +L+ QE + H +QQE +
Sbjct: 705 -QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Query: 354 -----------EHLEHQEGQLG----LPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQ 398
E E +L L EQ+ QL+ E+QQ + + L EEE + + Q
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
Query: 399 QEGQLKHL--VQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQ-QGQLEVPEQ 455
+ + K L +++E QL+++ER + E++ G + E + Q + +Q+ + QLE +
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERK 883
Query: 456 Q-----VGQPKNLEQ--EEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEK 508
+ +P EQ +E+QL E++E Q + EK+ Q + E+Q + + L+Q+E+
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ--ERQYREEEQLQQEEE 941
Query: 509 HLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL--EQP 543
L E++ + + E+Q + K L+Q++ QL E+P
Sbjct: 942 QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP 978
Score = 150 bits (380), Expect = 2e-36
Identities = 130/541 (24%), Positives = 285/541 (52%), Gaps = 34/541 (6%)
Query: 54 EVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKT 113
E+ +++E+ + EQ+ ++Q+E + ++ +++ +Q Q+ E EQQL++E+
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Query: 114 QR-DQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQ--QE 170
+R +QQL ++ EEE++ + +QE +R++QL +++ E ++E L+ +Q +E
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Query: 171 GQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE 230
QL+ +Q + +L +Q+ + E E++ Q E++E +L+ EQ+E + L ++E
Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR-EQEERRDWLKREEE 463
Query: 231 GQLELPQQQEGQLELSEQQEGQ---LELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLE 287
+ ++++ QL+ +++E + L+L E++ + + Q+ + E E + +LK E
Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523
Query: 288 QQEGQLKHLDQQEKQPELPEQQMGQL------KHLEQQEGQPKHLEQQEGQLEQLEEQEG 341
++E + L +++ E++ QL K LEQ+ + + +QE + +QL ++E
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE 583
Query: 342 QLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEG 401
+ + + Q E LE + L ++V +L+Q E+++ + K E EE + + L++ E
Sbjct: 584 ERRQQRLKREQEERLEQR-----LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 402 QLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPK 461
Q + QQ+ + EQQER+ + L++ EE+E +L+ +++ + E EQ++ + +
Sbjct: 639 QEERR-QQQLRREQQERREQRLKR--------EEEEERLEQRLKREHEEERREQELAEEE 689
Query: 462 NLEQEEK-QLELPEQQEGQVKHLEKQEAQL-ELPEQQVGQPKHLEQQEKHLEHPEQ---Q 516
+ E+ + +P+ Q + +++++ P +Q GQ + EQ+EK + Q
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ 749
Query: 517 DGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQ 576
+ + H +QQE + + + Q E+ + Q +P L + E L E +QQ++
Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEK--SERGRQRLSARPPLREQRERQLRAEERQQRE 807
Query: 577 E 577
+
Sbjct: 808 Q 808
Score = 147 bits (372), Expect = 2e-35
Identities = 141/566 (24%), Positives = 283/566 (50%), Gaps = 66/566 (11%)
Query: 58 KQEEKHMTAVKGLPEQE----CEQQQKEPQEQEL--QQQHWEQHEEYQKAENPEQQLKQE 111
K++E+ +G + E EQ+ ++ +++EL Q+Q W++ EE + E Q K
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199
Query: 112 KTQ--------------------RDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQ 151
+T+ R+++ ++ E + ++ ++ ++E KR+ L ++E+
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Query: 152 LLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELP-EQQEGQLELPEQQE 210
L E Q++ + L+++E QL+ E+QE + E E+++ Q L EQQ + + E++E
Sbjct: 260 LQEEEPQRQ---RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERRE 316
Query: 211 GQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQE 270
Q E EQQE + + E++E QL Q++ + +L +QE E++E QL+ + +E
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQE-----EERREQQLRREQEEE 371
Query: 271 GQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQE 330
+ E+Q+ + + L ++E QL+ Q ++ +L +Q QL+ EQQ + + L +++
Sbjct: 372 RR----EQQLRREQQL-RREQQLRREQQLRREQQLRREQ--QLRR-EQQLRREQQLRREQ 423
Query: 331 GQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEE 390
+ EE+ + KH +++ Q E +E + L ++ + + E+++ Q K +EEE
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483
Query: 391 GQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQL 450
+ + L +E + + QQE + +Q R+ E +Q +LK EE+E + L +Q
Sbjct: 484 RRERWLKLEEEERRE--QQERREQQLRREQEERREQ--RLKRQEEEERLQQRLRSEQQLR 539
Query: 451 EVPEQQVGQ------PKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLE 504
E++ Q K LEQE ++ L +QE + L K+E + + Q + LE
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 505 QQEK-----HLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPAL 559
Q+ K LE E+++ +LK E +E + + L + + Q E+ + Q ++
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER--------RQQQLRREQ 651
Query: 560 PTKGEVLLPVEHQQQKQEVQWPPKHK 585
+ E L E ++++ E + +H+
Sbjct: 652 QERREQRLKREEEEERLEQRLKREHE 677
Score = 145 bits (365), Expect = 1e-34
Identities = 128/481 (26%), Positives = 262/481 (54%), Gaps = 22/481 (4%)
Query: 70 LPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRD-QQLNKQLEEEKK 128
L E+E E Q++E +++ Q+Q + EE Q + EQ L++E+ +R Q+ +Q ++KK
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 129 LLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQ 188
L QQ +++L+ + + ++E+ + E++E L+Q+E QL E+++ + + E+
Sbjct: 966 L--QQKEEQLLGEEPEKRRRQEREKKYREEEE-----LQQEEEQLLREEREKRRRQEWER 1018
Query: 189 QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQ 248
Q + + +Q+E QL E+++ +L+ E+Q + E +Q+E QL +++ + + E+
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 249 QEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQ 308
Q + E +Q+E QL E ++ + + E Q + + L+Q+E QL ++++++ + E+
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138
Query: 309 QMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQ 368
Q + + ++Q+E Q E ++ + ++LE Q + + L+Q+E QL E QE + E+
Sbjct: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR-EEQEKRRQERER 1197
Query: 369 QVLQLKQLEKQQGQPKHLEEEE-GQLKHLVQQEGQ---LKHLVQQEGQLEQQERQVEHLE 424
Q + ++L++Q+ + ++ +E++ LK + E + + V +G+ +Q RQ+E
Sbjct: 1198 QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED-- 1255
Query: 425 QQVGQLKHLEEQEGQLKHL--EQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKH 482
QL+ + Q+ L+HL EQQ+ E ++ Q EE+QLE EQ+E + +
Sbjct: 1256 ---SQLRDRQSQQ-DLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD 1311
Query: 483 LEKQEAQLELPEQQVGQPKHLEQQEKHLEHPE-QQDGQLKHLEQQEGQLKDLEQQKGQLE 541
+ QE + L E++ + + E K E + Q+ + + L +QE K E++ E
Sbjct: 1312 RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQE 1371
Query: 542 Q 542
Q
Sbjct: 1372 Q 1372
Score = 139 bits (349), Expect = 9e-33
Identities = 144/527 (27%), Positives = 279/527 (52%), Gaps = 46/527 (8%)
Query: 58 KQEEKHMTAVKGLPEQEC--EQQQKEPQEQELQQQHWEQHEEYQKAENPEQ--QLKQEKT 113
+ EE+ + + KG +E E+Q + + EL+++ E+ ++ Q+ E ++ Q ++EK
Sbjct: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ-QRRERQDRVFQEEEEKE 245
Query: 114 QRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQL 173
R ++ + EEEK L +E +R +L ++EQL +L Q+ + E+Q+ Q
Sbjct: 246 WRKRETVLRKEEEK------LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR 299
Query: 174 KHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL--ELPEQQEGQLELPEQQEG 231
EQQ + + E++E Q E EQQE + + E++E QL E E++E QL EQ+E
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR-REQEEE 358
Query: 232 QLELPQQQEGQLELSEQQ---EGQLELSEQ--QEGQLKHLEHQEGQLEVPEEQMGQLKYL 286
+ E ++E + E EQQ E QL +Q +E QL+ + + ++ EQ + +
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 287 EQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLE-QQEGQLEQLEEQEGQLKH 345
++E QL+ ++E+ + EQ+ + + +QE + L+ ++E + + E ++ QLK
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
Query: 346 LEQQEG-----QLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQE 400
+++E +LE E +E Q +Q L+ +Q E+++ + K EEEE +L+ ++ E
Sbjct: 479 DQEEERRERWLKLEEEERREQQ--ERREQQLRREQEERREQRLKRQEEEE-RLQQRLRSE 535
Query: 401 GQLKH---------LVQQEGQLEQQERQVEHL----EQQVGQLKHLEEQEGQLKHLEQQQ 447
QL+ L ++E + +QER+ + L E++ QL EE+ Q + +Q+
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 448 GQLE--VPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQV--GQPKHL 503
+LE + ++V + + E+ E++L+ E +E + + L K E Q E +QQ+ Q +
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 504 EQQEKHLEHPEQQDGQLKHLEQQEGQLKDL-EQQKGQLEQPVFAPAP 549
EQ+ K E E+ + +LK ++E + ++L E+++ Q + + + P
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
Score = 138 bits (347), Expect = 2e-32
Identities = 129/534 (24%), Positives = 280/534 (52%), Gaps = 63/534 (11%)
Query: 53 VEVPSKQEEKHMTAVKGLPEQECEQQ------QKEPQEQELQQQHWEQHEEYQKAENPEQ 106
VE ++E + + PE+E QQ Q+E ++Q+L+++ E+ E+ K E E+
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 107 QLKQ------EKTQRDQQLNKQLEEE-KKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQ 159
+L+Q E+ +R+Q+L ++ +E+ ++ + ++ + + + + ++ ++ P +Q
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 160 EGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEG-----QLELPEQQE---- 210
EG + EQ+E + ++E +L+ E++ + E+++ Q + E+ E
Sbjct: 727 EGQRRRQEQEEKR----RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Query: 211 ---GQLELPEQQEGQLELPE-QQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHL 266
+ L EQ+E QL E QQ Q LP+++E + +++E + EL +E + L
Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE--QL 840
Query: 267 EHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHL-------EQQ 319
+ +E ++ EE+ G + E++ Q + DQ+ + +L E++ + L EQ
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRW-QLEEERKRRRHTLYAKPALQEQL 899
Query: 320 EGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQ 379
+ + L+++E +L++ E ++ + + E+Q + E L+ +E QL E++ + ++ E+Q
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 380 QGQPKHLEEEEGQL-----KHLVQQEGQLKH-----LVQQEGQL---EQQERQVEHLEQQ 426
+ K L+++E QL + +QE + K+ L Q+E QL E+++R+ + E+Q
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Query: 427 VGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQ 486
+ L+++E QL E+++ +L+ E+Q E+EE Q Q+E Q+ E++
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYR-----EEEELQ-----QEEEQLLGEERE 1069
Query: 487 EAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL 540
+ + E+Q + + L+Q+E+ L E + + + E+Q + ++L+Q++ QL
Sbjct: 1070 TRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Score = 134 bits (338), Expect = 2e-31
Identities = 152/553 (27%), Positives = 282/553 (50%), Gaps = 69/553 (12%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQL--KQEKTQR 115
+QE + K +QE EQ +E +E+ Q+ Q+ E ++ + E+QL ++ +T+R
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
Query: 116 DQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKH 175
Q+L +Q +E++L QQ +++L++ + + ++E+ + E++E L+Q+E QL
Sbjct: 1073 RQELERQYRKEEEL--QQEEEQLLREEPEKRRRQERERQCREEEE-----LQQEEEQLLR 1125
Query: 176 PEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL 235
E+++ + + E+Q + E +Q+E QL E PE++ Q EL Q + EL
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREE--------PEKRRRQ-ELERQYREEEEL 1176
Query: 236 PQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQE-GQLEVPEEQMGQLKYLEQQE---- 290
QQ+E QL L E+QE + + E+Q + + L+ Q+ Q E+Q LK+ + E
Sbjct: 1177 -QQEEEQL-LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
Query: 291 ---------GQLKHLDQQEKQPELPEQQMGQ-LKHL--EQQEGQPKHLEQQEGQLEQLEE 338
G+ +Q + +L ++Q Q L+HL EQQE + ++ Q ++
Sbjct: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Query: 339 QEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQP---KHLEEEEGQLKH 395
+E QL+ EQ+E + + QE E+Q+L+ ++ EK++ Q K EEE+
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQE------EKQLLREEREEKRRRQETDRKFREEEQ----- 1343
Query: 396 LVQQEGQLKHLVQQEGQLEQQERQVEHLEQQ---VGQLKHLEEQEGQLKHL-EQQQGQLE 451
+ QE + + L +QE + +E ++ H EQ + + + L QE + K L E+QQ + +
Sbjct: 1344 -LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ 1402
Query: 452 VPEQQVGQPKN--LEQEEKQLELPE------QQEGQVKHLEKQEAQLELPEQQVGQPKHL 503
EQQ+ Q ++ +EE+QL E ++E QV+ E++ LE EQQ+ Q +H
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE-EEQQLRQERHR 1461
Query: 504 EQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKG 563
+ +E+ E+++ QL E+ L++ +Q + Q F + Q+ + +
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE 1521
Query: 564 EVLLPVEHQQQKQ 576
+ L H+QQ+Q
Sbjct: 1522 QQL----HRQQRQ 1530
Score = 134 bits (338), Expect = 2e-31
Identities = 131/509 (25%), Positives = 269/509 (52%), Gaps = 43/509 (8%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQEL--QQQHWEQHEEYQKAENPEQQLKQEKTQR 115
++E K + + L QE EQQ ++ ++++ ++Q + E +K EQQ+++++ +R
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 116 -----DQQL----NKQLEEEKKLLDQQLDQELVK--RDEQLGMKKEQLLELPEQQEGHLK 164
+QQL +++ EE++LL ++ +Q+L + RD + +++QL ++ +
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
Query: 165 HLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLE 224
L QE + K E+++ QL ++Q L+ EQQ + E +Q+ + ++E QL
Sbjct: 1507 ELRSQEPERKFLEEEQ-QLHRQQRQRKFLQ-EEQQLRRQERGQQRRQDRDRKFREEEQLR 1564
Query: 225 LPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLK 284
E++E QL Q+++ + L EQ+ + E + + L QEGQ ++ +E+ + +
Sbjct: 1565 -QEREEQQLSR-QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFR 1622
Query: 285 YLEQ--QEGQLKHLDQQEK-------QPELPEQQMGQ-LKHLEQQEGQPKHLEQQEGQLE 334
EQ QE + + L +QE+ +P+L Q+ Q L+H ++ + + QEG+ +
Sbjct: 1623 EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQ 1682
Query: 335 QLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLK 394
QL QE K E+++ QL E + + L E+Q L+ ++LE++ + + L +E Q +
Sbjct: 1683 QLRRQERDRKFREEEQ-QLRRQERE--RKFLQEEQQLRRQELERKFREEEQLRQETEQ-E 1738
Query: 395 HLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPE 454
L +QE K L +++ + E++E+Q+ E+ + E+E + E+QQ + + +
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERD----RKFREEEQLRQEREEQQLRSQESD 1794
Query: 455 QQVGQPKNLEQEEKQLEL-PEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHP 513
++ + + L QE ++ +L P+Q++G+ + +E QL+L EQ+ + L Q+
Sbjct: 1795 RKFREEEQLRQEREEQQLRPQQRDGKYRW---EEEQLQLEEQE----QRLRQERDRQYRA 1847
Query: 514 EQQDGQLKHLEQQEGQLKDLEQQKGQLEQ 542
E+Q + ++E +L E+QK + E+
Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKRRQER 1876
Score = 134 bits (337), Expect = 2e-31
Identities = 141/535 (26%), Positives = 269/535 (50%), Gaps = 60/535 (11%)
Query: 72 EQECEQQQKEPQEQELQQQ-HWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLL 130
EQ+ +Q++E + E +QQ E+H ++++ E Q+ ++++ R ++ K LEEE++L
Sbjct: 1436 EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR 1495
Query: 131 DQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQE 190
Q+ D++ R+++L ++ + L E+Q+ H +Q++ + EQQ + E +Q+
Sbjct: 1496 RQERDRKF--REQELRSQEPERKFLEEEQQ---LHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 191 GQLELPEQQEGQLELPEQQEGQLELPEQ------QEGQLELPEQQEGQLELPQQ---QEG 241
+ ++E QL E++E QL E+ +E ++ EQ+ +E QQ QEG
Sbjct: 1551 QDRDRKFREEEQLR-QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Query: 242 QLELSEQQEGQLELSEQ--QEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQ 299
Q +L ++++ + EQ QE + + L QE + EE+ QL+ E+++ QL+H +
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP-QLRRQEREQ-QLRHDRDR 1667
Query: 300 EKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEG----QLEH 355
+ + E Q G+ + L +QE K E+++ QL QE + K L++++ +LE
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQ----QLRRQERERKFLQEEQQLRRQELER 1723
Query: 356 LEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEE----EGQLKHLVQQEGQLKHLVQQEG 411
+E QL +Q + +QL +Q+ K LEEE E + + L +QE K ++E
Sbjct: 1724 KFREEEQL----RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF--REEE 1777
Query: 412 QLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQ------QGQLEVPEQQV---GQPKN 462
QL +QER+ + L Q K EE++ + + EQQ G+ E+Q+ Q +
Sbjct: 1778 QL-RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836
Query: 463 LEQE-EKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLK 521
L QE ++Q EQ Q K +++ + EQ+ Q + + +E+H+ +++
Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE----- 1891
Query: 522 HLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQ 576
EQ+ Q+ +++ Q+G+ + P Q + P + L +Q+ Q
Sbjct: 1892 --EQRHRQVGEIKSQEGKGHGRLLEPGTHQFASV----PVRSSPLYEYIQEQRSQ 1940
Score = 131 bits (330), Expect = 2e-30
Identities = 132/500 (26%), Positives = 259/500 (51%), Gaps = 49/500 (9%)
Query: 72 EQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLD 131
E++ + +++E + QE ++ E+ + ++ E + LK+E+ R Q+ +QL +++
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416
Query: 132 QQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEG 191
++ +Q+L +++ ++E+ +++E EQQ Q +H + +E + L E++E
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476
Query: 192 QLELPEQQEGQLELPEQ---QEGQLELPEQQEGQLELPEQQ--EGQLELPQQQEGQLELS 246
QL E+ LE +Q QE + EQ+ E PE++ E + +L +QQ + L
Sbjct: 1477 QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE-PERKFLEEEQQLHRQQRQRKFLQ 1535
Query: 247 EQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELP 306
E+Q+ + + QQ Q + + +E + ++ +E+ Q ++++ + + +Q+ ++ E
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEE-QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 307 EQQMGQLKHLEQQEGQPKHLEQ------------QEGQLEQLEEQEGQLKHLEQQ----- 349
+ M + L +QEGQ + ++ QE + +QL QE K LE++
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654
Query: 350 EGQLEHLEHQEGQLGLPEQQVLQ---LKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHL 406
+ + + L H + E+Q+LQ +QL +Q+ K EEE+ L +QE + K L
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ----QLRRQERERKFL 1710
Query: 407 VQQEGQLEQQE-----RQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPK 461
Q+E QL +QE R+ E L Q+ Q + L QE K LE++Q + E EQQ+ + +
Sbjct: 1711 -QEEQQLRRQELERKFREEEQLRQETEQ-EQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 462 NLE--QEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQ 519
+EE+QL +QE + + L QE+ + E++ + + EQQ + P+Q+DG+
Sbjct: 1769 RDRKFREEEQL----RQEREEQQLRSQESDRKFREEEQLRQEREEQQLR----PQQRDGK 1820
Query: 520 LKHLEQQEGQLKDLEQQKGQ 539
+ E+++ QL++ EQ+ Q
Sbjct: 1821 YR-WEEEQLQLEEQEQRLRQ 1839
Score = 127 bits (319), Expect = 3e-29
Identities = 138/535 (25%), Positives = 271/535 (50%), Gaps = 64/535 (11%)
Query: 54 EVPSKQE-EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEK 112
E +QE E+ + L ++E + ++EP+++ Q++ + EE + + EQ L++E+
Sbjct: 1069 ETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER 1128
Query: 113 TQRD-QQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEG 171
+R Q+L +Q EE+++ QQ +++L++ + + ++E + E++E L+Q+E
Sbjct: 1129 EKRRRQELERQYREEEEV--QQEEEQLLREEPEKRRRQELERQYREEEE-----LQQEEE 1181
Query: 172 QLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEG 231
QL EQ++ + E Q + EL Q+ Q E Q L+ + E + + + +
Sbjct: 1182 QLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVY 1241
Query: 232 QLELPQQQEGQLELSE------QQEGQLELSEQQEG--QLKHLEHQEGQLEVPEEQMGQL 283
+Q QLE S+ QQ+ Q L EQQE + + Q+ PEE+ QL
Sbjct: 1242 CKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE--QL 1299
Query: 284 KYLEQQEGQLKHLDQQEKQPELPEQQMGQLKH-------------LEQQEGQPKHLEQQE 330
+ EQ+E + + QE++ L E++ + + L+++E QP ++++
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
Query: 331 GQL--EQLEEQEGQLKHLEQQEGQLEHLEHQEGQLG-LPEQQVLQLKQLEKQ--QGQPKH 385
+ E+L QE K LE+++ L QE + L E+Q L+ ++ E+Q Q + +
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQ----RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 386 LEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLE--QQVGQLKH---------LE 434
EEE QL +QE K ++E Q+ +QER+ + LE QQ+ Q +H L+
Sbjct: 1416 FREEEQQLS---RQERDRKFR-EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ 1471
Query: 435 EQEGQLKHLEQQQGQLEVPEQQV---GQPKNLEQEEKQLELPEQ---QEGQVKHLEKQEA 488
E+E Q H +++ + EQQ+ + + ++E + + PE+ +E Q H ++++
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Query: 489 QLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQ-QKGQLEQ 542
+ EQQ+ + + +Q+ + + +++ QL+ E++E QL E+ +K +LE+
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ-EREEQQLSRQERDRKFRLEE 1585
Score = 127 bits (318), Expect = 4e-29
Identities = 141/540 (26%), Positives = 275/540 (50%), Gaps = 56/540 (10%)
Query: 31 QEQMKQPTPLPPPCQKVPVELPVEVPSK---QEEKHMTAVKGLPEQECEQQQKEPQEQEL 87
QEQ+++ L Q+ EL E K QE++ + +QE EQ +E +E+
Sbjct: 896 QEQLRKEQQL---LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
Query: 88 QQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGM 147
+Q+ Q+ + +K + E+QL E+ ++ ++ E EKK +++ EL + +EQL
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEK----RRRQEREKKYREEE---ELQQEEEQLLR 1005
Query: 148 KKEQLLELPEQQEGHLK--HLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLEL 205
++ + E + + K L+Q+E QL E+++ +L+ E+Q + E +Q+E QL L
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL-L 1064
Query: 206 PEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKH 265
E++E ++ +LE ++E +L QQ+E QL E ++ + + E+Q + +
Sbjct: 1065 GEERE------TRRRQELERQYRKEEEL---QQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 266 LEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKH 325
L+ +E QL E + + + LE+Q + + + Q+E+Q E + + + LE+Q + +
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 326 LEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE-GQLGLPEQQVLQLK---QLEKQQG 381
L+Q+E QL + EEQE + + E+Q + E L+ Q+ Q E Q LK + EK+
Sbjct: 1176 LQQEEEQLLR-EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
Query: 382 ------------QPKHLEEEEGQLKHLVQQEGQLKHLV--QQEGQLEQQERQVEHLEQQV 427
+ + E+ QL+ Q + L+HL+ QQE EQ+ R+ + ++
Sbjct: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDR-QSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293
Query: 428 GQLKHL--EEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQ--QEGQVKHL 483
+ + L EEQ+ + + Q + ++ ++ + + ++ +++ EQ QE + + L
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353
Query: 484 EKQEAQLELPEQQVGQPKHLEQQEKHLEHPE---QQDGQLKHL-EQQEGQLKDLEQQKGQ 539
+QE + E+++ +H EQ K LE + +Q+ + K L E+Q+ + ++ EQQ Q
Sbjct: 1354 RRQERDRKFREEEL---RHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Score = 122 bits (306), Expect = 9e-28
Identities = 133/523 (25%), Positives = 265/523 (50%), Gaps = 73/523 (13%)
Query: 57 SKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRD 116
S+Q+ +H+ L EQ+ +++E + + + +H+ + E+ ++ E E + + K+Q +
Sbjct: 1263 SQQDLQHL-----LGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317
Query: 117 QQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHP 176
+QL ++ EEK+ Q+ D++ + ++ L ++EQ L E+ + +E +L+H
Sbjct: 1318 KQLLREEREEKRRR-QETDRKFREEEQLLQEREEQPLRRQERDR------KFREEELRHQ 1370
Query: 177 EQQEGQLELPEQQEGQLELPEQQEGQLELPEQ---QEGQLELPEQQEGQLELPEQQEGQL 233
EQ LE +E +L E++ L+ +Q QE + +L + ++ + EQQ +
Sbjct: 1371 EQGRKFLE----EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 234 ELPQ---QQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQL------- 283
E + ++E Q+ E++ LE EQQ Q +H + +E + + E + QL
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLE-EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Query: 284 KYLEQQEGQLKHLDQQEKQPELPEQQ----------MGQLKHLEQQEGQPKHLEQQEGQL 333
K+LE+++ L +QE+ + EQ+ + + + L +Q+ Q K L Q+E QL
Sbjct: 1486 KFLEEEQ----QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL-QEEQQL 1540
Query: 334 EQLE-------------EQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQ 380
+ E +E QL+ E++E QL E ++ + L EQ+V + +Q K
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQ-EREEQQLSRQE-RDRKFRLEEQKVRRQEQERKFM 1598
Query: 381 GQPKHLEEEEGQLKHLVQQEGQLKHLVQ-----QEGQLEQQERQVEHLEQQVGQLKHLEE 435
+ L +EGQ + +++ + + Q +E QL +QER + LE++ QL+ +E
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEE-PQLRR-QE 1656
Query: 436 QEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLE-LPE 494
+E QL+H ++ + E Q G+ + L ++E+ + E+++ L +QE + + L E
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ----QLRRQERERKFLQE 1712
Query: 495 QQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQK 537
+Q + + LE++ + E Q+ Q + L +QE K LE+++
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQ-EQLRRQERYRKILEEEQ 1754
Score = 121 bits (303), Expect = 2e-27
Identities = 138/534 (25%), Positives = 272/534 (50%), Gaps = 64/534 (11%)
Query: 27 VNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQE 86
V +EQ+ + P Q++ + E +QEE+ + E+Q+K QE+E
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR---------EEQEKRRQERE 1196
Query: 87 LQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLG 146
Q + + EE Q+ + +Q+ + E + D + + E+E + D ++ + + ++
Sbjct: 1197 RQ---YREEEELQR-QKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 147 MKKEQLLELPEQQEGHLKHL--EQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLE 204
++ QL + QQ+ L+HL EQQE + ++ Q + +E QLE EQ+E +
Sbjct: 1253 LEDSQLRDRQSQQD--LQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310
Query: 205 LPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQ----QE 260
+ QE + L E++E E +QE + ++E QL L E++E L E+ +E
Sbjct: 1311 DRKSQEEKQLLREERE---EKRRRQETDRKF--REEEQL-LQEREEQPLRRQERDRKFRE 1364
Query: 261 GQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQ---QEKQPELPEQQMGQLKHLE 317
+L+H E +G+ + EEQ +L+ E++ LK Q QE++ +L + + + + E
Sbjct: 1365 EELRHQE--QGRKFLEEEQ--RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Query: 318 QQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLK--- 374
QQ + + + + +Q+ QE + K LE+++ QL H++ + E+Q+LQ +
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERERKFLEEEQ-QLRQERHRKFR---EEEQLLQEREEQ 1476
Query: 375 QLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLE 434
QL +Q+ K LEEE+ L +QE K +E +L QE + + LE++ + L
Sbjct: 1477 QLHRQERDRKFLEEEQ----QLRRQERDRKF---REQELRSQEPERKFLEEE----QQLH 1525
Query: 435 EQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEK---QLELPEQQEGQVKHLEKQEAQLE 491
Q+ Q K L+++Q ++ Q+ GQ + +++ K + +L +++E Q ++++ +
Sbjct: 1526 RQQRQRKFLQEEQ---QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 492 LPEQQVGQPKHLEQQEKHLEHPEQ---QDGQLKHLEQQEGQLKDLEQQKGQLEQ 542
L EQ+V + EQ+ K +E +Q Q+GQ + ++++ + ++ EQ + E+
Sbjct: 1583 LEEQKV---RRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE 1633
Score = 119 bits (297), Expect = 1e-26
Identities = 110/444 (24%), Positives = 235/444 (52%), Gaps = 27/444 (6%)
Query: 96 EEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLEL 155
E+ + + E L+ + + DQ ++ E D+QL++E +R Q ++E+ L
Sbjct: 98 EKRARCDGKESLLQDRRQEEDQ---RRFEPR----DRQLEEEPGQRRRQKRQEQERELAE 150
Query: 156 PEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL 215
E+Q + LEQ++ Q + E + E E++E + E + Q + E+ + +L
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 216 PEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLE--LSEQQEGQLKHLEHQEGQL 273
++ +L ++E Q + ++Q+ + E++E + + ++E +L+ E Q Q
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR-QR 269
Query: 274 EVPEEQMGQLKYLEQQEGQLKHLDQQEKQPEL-PEQQMGQLKHLEQQEGQPKHLEQQEGQ 332
E+ EE+ QL+ LE+QE + + +++++Q L EQQ+ + + E++E Q + EQQE +
Sbjct: 270 ELQEEEE-QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Query: 333 LEQLEEQEGQLKHLEQQEGQLEHL------EHQEGQLGLPEQQVLQLKQLEKQQGQPKHL 386
+Q E +E QL+ EQ+E + + L E +E QL +++ + +QL ++Q +
Sbjct: 329 EQQEERREQQLRR-EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ---QLR 384
Query: 387 EEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQ 446
E++ + + +++E QL+ +Q+ + EQQ R+ + L ++ + EE+ + KH +++
Sbjct: 385 REQQLRREQQLRREQQLRR--EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Query: 447 QGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVK---HLEKQEAQLELPEQQVGQPKHL 503
+ Q EQ+ + +EE + E+++ Q+K E++E L+L E++ + +
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 504 EQQEKHLEHPEQQDGQLKHLEQQE 527
+Q+ E E+++ +LK E++E
Sbjct: 503 REQQLRREQEERREQRLKRQEEEE 526
Score = 112 bits (281), Expect = 7e-25
Identities = 106/441 (24%), Positives = 244/441 (55%), Gaps = 22/441 (4%)
Query: 111 EKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQE 170
+ T D++ + + ++ LL + +E +R E + E+ +Q+ + E E
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Query: 171 GQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ--QEGQLELPEQQEGQLELPEQ 228
G+ + +Q+ +LE ++Q EL Q++ E E+ +E QL+ + E + E P++
Sbjct: 151 GEEQSEKQE--RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETE-EFPDE 207
Query: 229 QEGQ----LELPQ--QQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQ 282
++ + LEL + ++E Q + E+Q+ + E++E + + ++ + ++ EE+ +
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Query: 283 LKYLEQQEGQLKHLDQQEKQPELPEQQMGQLK-HLEQQEGQPKHLEQQEGQLEQLEEQEG 341
+ L+++E QL+ L++QE + E E++ Q + EQQ + + E++E Q E+ E+QE
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Query: 342 QLKHLEQQEGQL--EHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQ 399
+ + E++E QL E E +E QL +++ + +QL ++Q + + E++ + + +++
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER--REQQLRREQQLRR 385
Query: 400 EGQLKHLVQQEGQLEQQERQVEHL--EQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQV 457
E QL+ +Q+ + EQQ R+ + L EQQ+ + + L ++ + E+++ + + +++
Sbjct: 386 EQQLRR--EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Query: 458 GQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLE-QQEKHLEHPEQQ 516
Q EQEE++ L ++E + E+++ QL+ +++ + + L+ ++E+ E E++
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503
Query: 517 DGQLKHLEQQEGQLKDLEQQK 537
+ QL+ EQ+E + + L++Q+
Sbjct: 504 EQQLRR-EQEERREQRLKRQE 523
Score = 107 bits (266), Expect = 4e-23
Identities = 117/459 (25%), Positives = 228/459 (49%), Gaps = 73/459 (15%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQ---------- 107
+++ K + + L QE QQ+++ ++++ ++ EE + E EQQ
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE------EEQLRQEREEQQLSRQERDRKF 1581
Query: 108 -LKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHL 166
L+++K +R +Q K +E+E++L Q+ Q+L + ++ + EQLL+ E+Q+ L
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ-----L 1636
Query: 167 EQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ--QEGQLELPEQQEGQLE 224
+QE K E +E QL +QE + +L ++ + EQ QEG+ + +QE +
Sbjct: 1637 HRQERDRKFLE-EEPQL---RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK 1692
Query: 225 LPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLK 284
E+++ +L +Q+ + L E+Q+ +QE + K E ++ + E +EQ
Sbjct: 1693 FREEEQ---QLRRQERERKFLQEEQQ-----LRRQELERKFREEEQLRQETEQEQ----- 1739
Query: 285 YLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQ----QEGQLEQLEEQE 340
L +QE K L++++ +PE EQQ L +QE K E+ QE + +QL QE
Sbjct: 1740 -LRRQERYRKILEEEQLRPEREEQQ------LRRQERDRKFREEEQLRQEREEQQLRSQE 1792
Query: 341 GQLKHLEQQEGQLEHLEHQ------EGQLGLPEQQVLQLKQLE---KQQGQPKHLEEEEG 391
K E+++ + E E Q +G+ E+Q LQL++ E +Q+ ++ EE+
Sbjct: 1793 SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQ-LQLEEQEQRLRQERDRQYRAEEQF 1851
Query: 392 QLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLE 451
+ ++E Q L Q+E Q +QER+ + E+ + + + E++ Q+ ++ Q+G+
Sbjct: 1852 ATQEKSRREEQ--ELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK-- 1907
Query: 452 VPEQQVGQPKNLEQEEKQL-ELPEQQEGQVKHLEKQEAQ 489
G + LE Q +P + +++++Q +Q
Sbjct: 1908 ------GHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
Score = 85.5 bits (210), Expect = 1e-16
Identities = 87/334 (26%), Positives = 173/334 (51%), Gaps = 28/334 (8%)
Query: 229 QEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQ 288
+E L+ +Q+E Q E ++ QLE Q + K E QE +L EEQ + + LEQ
Sbjct: 106 KESLLQDRRQEEDQRRF-EPRDRQLEEEPGQRRRQKRQE-QERELAEGEEQSEKQERLEQ 163
Query: 289 QEGQLK-------HLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEG 341
++ Q + + QE++ E++ Q + E P + + +L +L +
Sbjct: 164 RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGR 223
Query: 342 QLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQP---KHLEEEEGQLKHLVQ 398
+ K +++E Q + +E + + VL+ ++ + Q+ +P + L+EEE QL+ L +
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 399 QEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVG 458
QE +++E Q E+Q++Q EQQ+ + + E +E Q + EQQ+ + + E++
Sbjct: 284 QE------LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337
Query: 459 QPKNLEQEEKQLELPEQQEGQVKHLE-KQEAQLELPEQQVGQPKHL--EQQ---EKHLEH 512
Q + ++E ++ +L +QE + + + ++E + E EQQ+ + + L EQQ E+ L
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397
Query: 513 PEQ--QDGQLKHLEQ--QEGQLKDLEQQKGQLEQ 542
+Q ++ QL+ +Q +E QL+ +Q + + E+
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Score = 32.3 bits (72), Expect = 1.2
Identities = 28/111 (25%), Positives = 58/111 (52%), Gaps = 14/111 (12%)
Query: 438 GQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLE----LPEQQEGQVKHLEKQEAQLELP 493
GQ L++++ ++ + Q + E+++++ E E++ GQ + ++QE + EL
Sbjct: 90 GQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELA 149
Query: 494 EQQVGQPKHLEQQEKHLEHPEQQDGQLK--HLEQQEGQLKDLEQQKGQLEQ 542
E + EQ EK E EQ+D Q + L +Q + ++ E+++ + EQ
Sbjct: 150 EGE-------EQSEKQ-ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ 192
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 143 bits (361), Expect = 4e-34
Identities = 143/414 (34%), Positives = 217/414 (52%), Gaps = 74/414 (17%)
Query: 181 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ-QEGQLELPEQQEGQLELPQQQ 239
G E E++E Q Q + P G E+ E+ + GQ EL QQ Q PQQQ
Sbjct: 47 GGSESQEEEEPQERNSSPQRPAVSAPV---GASEIAEETRPGQRELQLQQLEQQPEPQQQ 103
Query: 240 EGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQ 299
Q E +Q + LEL +Q + Q+GQ QL L+Q++ Q H Q
Sbjct: 104 P-QHEQLQQPQPHLELQQQPQ--------QDGQ--------QQLSQLQQEKHQSVH--HQ 144
Query: 300 EKQPELPEQQMGQLKHLEQQEGQPKHLEQQ---EGQLEQLEEQEGQLKHLEQQEGQLEHL 356
E +PEL QL H +QQ+ QP+ +++Q + Q EQL+ Q+ Q + + QQ+ QL+
Sbjct: 145 ELKPEL------QLMH-QQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQ- 196
Query: 357 EHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQ 416
+ QE QL +Q+ LQ +QL +QQ Q L++++ Q + Q+ Q L+QQ+GQL+QQ
Sbjct: 197 QVQEQQLLQQQQEQLQQQQLLQQQEQ---LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQ 253
Query: 417 --ERQVEHLEQQVGQLKHLEEQEGQLKH--LEQQQGQLEVPEQQVGQPKNLEQEEKQLEL 472
++Q L+QQ+ LE+Q+ QL+ L QQQ QL+ +QQ + L+Q+++QL+
Sbjct: 254 LLQQQQAQLQQQL-----LEQQQAQLQQQLLLQQQEQLQQQQQQ----QLLQQQQEQLQQ 304
Query: 473 PEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLE-------HPEQQDGQLKHLEQ 525
+ Q ++ E++E +LEL +G + LEQQ + LE EQ+ QLK E+
Sbjct: 305 QQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEE 364
Query: 526 QEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQ 579
+ + LEQQ+ QLEQ Q++Q L PVE Q+QEVQ
Sbjct: 365 LQQLEQQLEQQQQQLEQ----------QEVQLE-------LTPVELGAQQQEVQ 401
Score = 143 bits (361), Expect = 4e-34
Identities = 129/382 (33%), Positives = 210/382 (54%), Gaps = 28/382 (7%)
Query: 111 EKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQE 170
E + ++ + ++ + + + + + G ++ QL +L +Q E QQ+
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPE------PQQQ 103
Query: 171 GQLKHPEQQEGQLELPEQ--QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ 228
Q + +Q + LEL +Q Q+GQ +L + Q+ + + QE + EL + Q P+Q
Sbjct: 104 PQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQ 163
Query: 229 QEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQ 288
+ Q L QQQE QL+ + QE Q+ QQ+ QL+ ++ L+ +EQ+ Q + L+Q
Sbjct: 164 VQEQQRLQQQQE-QLQTQQAQEQQVL---QQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQ 219
Query: 289 QEGQLKHLDQQEKQPELPEQQMGQLKHLEQQ-EGQPKHLEQQEGQLEQ--LEEQEGQLKH 345
QE QL+ Q++Q +L +QQ QL L+QQ + Q + L+QQ+ QL+Q LE+Q+ QL+
Sbjct: 220 QE-QLQQQQFQQQQEQLQQQQ--QLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQ 276
Query: 346 --LEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQL 403
L QQ+ QL+ + Q+ QL +Q+ LQ +QL+ +P+ EEEE +L+ + G
Sbjct: 277 QLLLQQQEQLQ--QQQQQQLLQQQQEQLQQQQLQPPPLEPE--EEEEVELELMPVDLGSE 332
Query: 404 KHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVG-QPKN 462
+ L QQ +LE+Q+ EQ+ QLK EE + + LEQQQ QLE E Q+ P
Sbjct: 333 QELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVE 392
Query: 463 L--EQEEKQLEL-PEQQEGQVK 481
L +Q+E QLEL P Q E Q++
Sbjct: 393 LGAQQQEVQLELTPVQPELQLE 414
Score = 143 bits (360), Expect = 5e-34
Identities = 139/412 (33%), Positives = 221/412 (53%), Gaps = 36/412 (8%)
Query: 167 EQQEGQLKHPEQQEGQLELPEQQEGQLELPEQ-QEGQLELPEQQEGQLELPEQQEGQLEL 225
E++E Q ++ Q + P G E+ E+ + GQ EL QQ Q P+QQ Q E
Sbjct: 53 EEEEPQERNSSPQRPAVSAPV---GASEIAEETRPGQRELQLQQLEQQPEPQQQP-QHEQ 108
Query: 226 PEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKY 285
+Q + LEL QQ QQ+GQ +LS+ Q+ + + + HQE + E+ + M Q +
Sbjct: 109 LQQPQPHLELQQQ--------PQQDGQQQLSQLQQEKHQSVHHQELKPEL--QLMHQQQQ 158
Query: 286 LEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKH 345
L+ Q+ Q + QQ+ Q +L QQ + + L+QQE + +++Q QL Q ++++ Q +
Sbjct: 159 LQPQQVQEQQRLQQQ-QEQLQTQQAQEQQVLQQQEQLQQQVQEQ--QLLQQQQEQLQQQQ 215
Query: 346 LEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKH--LVQQEGQL 403
L QQ+ QL+ + Q+ Q L +QQ L L Q ++ Q Q + L++++ QL+ L QQ+ QL
Sbjct: 216 LLQQQEQLQQQQFQQQQEQLQQQQQLLLLQ-QQGQLQQQLLQQQQAQLQQQLLEQQQAQL 274
Query: 404 KH--LVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPK 461
+ L+QQ+ QL+QQ++Q + L+QQ QL+ + Q L+ E+++ +LE+ +G +
Sbjct: 275 QQQLLLQQQEQLQQQQQQ-QLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQ 333
Query: 462 NLEQE----EKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQD 517
LEQ+ E+Q EL QQE + L+ QE +L +Q Q + LEQQE LE +
Sbjct: 334 ELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVEL 393
Query: 518 GQLKHLEQQEGQLK-DLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLP 568
G +QQE QL+ Q + QLE PA G P P V P
Sbjct: 394 G----AQQQEVQLELTPVQPELQLE---LVPAAGGGGAAVPGAPAAVVVAPP 438
Score = 134 bits (336), Expect = 3e-31
Identities = 112/346 (32%), Positives = 189/346 (54%), Gaps = 42/346 (12%)
Query: 17 QELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECE 76
Q+L + P EQ++QP P Q+ + ++ Q+EKH Q
Sbjct: 92 QQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKH---------QSVH 142
Query: 77 QQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQ 136
Q+ +P+ Q + QQ Q ++ Q+ + +QQ +Q +TQ+ Q+ +Q+ ++++ L QQ+ +
Sbjct: 143 HQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQE--QQVLQQQEQLQQQVQE 200
Query: 137 ELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELP 196
+ + + +Q ++++QLL+ EQ L+QQ+ Q + + Q+ Q L QQ+GQL
Sbjct: 201 QQLLQQQQEQLQQQQLLQQQEQ-------LQQQQFQQQQEQLQQQQQLLLLQQQGQL--- 250
Query: 197 EQQEGQLELPEQQEGQL--ELPEQQEGQL--ELPEQQEGQLELPQQQEGQLELSEQQEGQ 252
Q +L +QQ+ QL +L EQQ+ QL +L QQ+ QL+ QQQ +L +QQ+ Q
Sbjct: 251 -----QQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQ----QLLQQQQEQ 301
Query: 253 LELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQL---KHLDQQEKQPELPEQQ 309
L+ + Q L+ E +E +LE+ +G + LEQQ +L + L++Q++Q +L +
Sbjct: 302 LQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKL 361
Query: 310 MGQLKHLEQQ-EGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLE 354
+L+ LEQQ E Q + LEQQE QLE + G +QQE QLE
Sbjct: 362 QEELQQLEQQLEQQQQQLEQQEVQLELTPVELG----AQQQEVQLE 403
Score = 132 bits (331), Expect = 1e-30
Identities = 129/402 (32%), Positives = 209/402 (51%), Gaps = 56/402 (13%)
Query: 29 THQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQ---QKEPQEQ 85
+ ++ ++P Q+ V PV EE + L Q+ EQQ Q++PQ +
Sbjct: 49 SESQEEEEPQERNSSPQRPAVSAPVGASEIAEETR-PGQRELQLQQLEQQPEPQQQPQHE 107
Query: 86 ELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQ-LEEEKKLL--DQQLDQELVKRD 142
+LQQ + Q ++ +QQL Q + ++ Q ++ Q L+ E +L+ QQL + V+
Sbjct: 108 QLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQ 167
Query: 143 EQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQ 202
++L ++EQL + Q+ + + QQ+ QL+ Q++ L+ ++Q Q +L +QQE Q
Sbjct: 168 QRLQQQQEQL----QTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE-Q 222
Query: 203 LELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQ 262
L+ + Q+ Q +L +QQ+ L L +Q + Q +L QQQ+ QL Q +L EQQ+ Q
Sbjct: 223 LQQQQFQQQQEQLQQQQQ-LLLLQQQGQLQQQLLQQQQAQL--------QQQLLEQQQAQ 273
Query: 263 LKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQ 322
L Q + L QQ+ QL QQ++Q +L +QQ Q L+QQ+ Q
Sbjct: 274 L------------------QQQLLLQQQEQL----QQQQQQQLLQQQQEQ---LQQQQLQ 308
Query: 323 PKHL---EQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQ 379
P L E++E +LE + G + LEQQ +LE + E Q EQ+ LQLK E+
Sbjct: 309 PPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQ---QEQRQLQLKLQEEL 365
Query: 380 QGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVE 421
Q + LE+++ QL+ QQE QL+ L E +QQE Q+E
Sbjct: 366 QQLEQQLEQQQQQLE---QQEVQLE-LTPVELGAQQQEVQLE 403
Score = 90.1 bits (222), Expect = 5e-18
Identities = 87/251 (34%), Positives = 139/251 (55%), Gaps = 41/251 (16%)
Query: 348 QQEGQLEHLEHQEGQLGLPE-QQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHL 406
Q+E QL+ LE Q PE QQ Q +QL QQ QP HLE L+ QQ+GQ
Sbjct: 86 QRELQLQQLEQQ------PEPQQQPQHEQL--QQPQP-HLE-----LQQQPQQDGQ---- 127
Query: 407 VQQEGQLEQQERQVEHLEQQVGQLKHLEEQE-------GQLKHLEQQQGQL---EVPEQQ 456
QQ QL+Q++ Q H ++ +L+ + +Q+ + + L+QQQ QL + EQQ
Sbjct: 128 -QQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQ 186
Query: 457 V-GQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQ 515
V Q + L+Q+ ++ +L +QQ+ Q++ + + Q +L +QQ Q + QQ++ L +Q
Sbjct: 187 VLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQ 246
Query: 516 QDGQLKH--LEQQEGQLKD--LEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEH 571
Q GQL+ L+QQ+ QL+ LEQQ+ QL+Q + Q+Q Q + ++L +
Sbjct: 247 Q-GQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQ-----QQQLLQQQQE 300
Query: 572 QQQKQEVQWPP 582
Q Q+Q++Q PP
Sbjct: 301 QLQQQQLQPPP 311
Score = 66.6 bits (161), Expect = 6e-11
Identities = 57/145 (39%), Positives = 83/145 (57%), Gaps = 22/145 (15%)
Query: 73 QECEQQQKEPQEQELQQQHWEQHEEYQKAENP-----EQQLKQEKTQRDQQLNKQLEEEK 127
Q+ EQ Q++ Q+Q LQQQ EQ ++ Q P E++++ E D ++LE+++
Sbjct: 281 QQQEQLQQQQQQQLLQQQQ-EQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQR 339
Query: 128 KLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELP- 186
+ L++Q + E + QL +K ++ L+ EQQ LEQQ+ QL EQQE QLEL
Sbjct: 340 QELERQQELERQQEQRQLQLKLQEELQQLEQQ------LEQQQQQL---EQQEVQLELTP 390
Query: 187 -----EQQEGQLEL-PEQQEGQLEL 205
+QQE QLEL P Q E QLEL
Sbjct: 391 VELGAQQQEVQLELTPVQPELQLEL 415
Score = 36.6 bits (83), Expect = 0.066
Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 13/118 (11%)
Query: 31 QEQMKQPTPLPPPCQK-VPVEL-PVEVPSKQE-EKHMTAVKGLPEQECEQQQKEPQE--- 84
Q+Q QP PL P ++ V +EL PV++ S+QE E+ ++ E E +Q+Q++ Q
Sbjct: 303 QQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQ 362
Query: 85 ---QELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELV 139
Q+L+QQ ++ Q+ E E QL+ + Q ++++ E + +L ELV
Sbjct: 363 EELQQLEQQ---LEQQQQQLEQQEVQLELTPVELGAQ-QQEVQLELTPVQPELQLELV 416
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 127 bits (319), Expect = 3e-29
Identities = 120/475 (25%), Positives = 252/475 (53%), Gaps = 25/475 (5%)
Query: 50 ELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLK 109
EL + +QEEK + + E E + Q++E + +E +++ EQ E+ ++ E + K
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE-K 347
Query: 110 QEKTQRDQQLNKQLEEEKKLLDQQL---DQELVKRDEQLGMKKEQLLELPEQQEGHLKHL 166
+EK +R +++ + EE+ + ++ + ++++ +++E + K+E++ EL E+ K
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 407
Query: 167 EQQEGQLKHPE--QQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLE 224
EQ+E + + + +QE + E + Q E +QE ++ E++ + E ++ ++
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467
Query: 225 LPEQQEGQLELPQQQEG---QLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMG 281
E+++ Q E+ +Q+E Q E+ Q+E E E+ Q + + QE ++ EE++
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 282 -QLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQE 340
Q + + +QE +++ ++ ++ E +Q + ++QE + K Q+E EQ E+
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 341 GQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQ-- 398
Q + + +QE E + QE ++ E+++ + Q EK Q Q + + E+E +++ +
Sbjct: 588 RQEEKIREQE---EKRQEQEEKMWKQEEKIRE--QEEKIQEQEEKIREQEEKIREQEEMT 642
Query: 399 QEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQ-QGQLEVPEQQV 457
QE + K Q+E EQ+E+ E E Q + + EQE +++ E++ + Q E+ ++Q
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ- 701
Query: 458 GQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEH 512
+ K EQEEK E E+ + Q + + +QE ++ EQ+V + +Q+EK EH
Sbjct: 702 -EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW--EQEV---RLRQQEEKMQEH 750
Score = 115 bits (289), Expect = 9e-26
Identities = 119/519 (22%), Positives = 269/519 (51%), Gaps = 40/519 (7%)
Query: 84 EQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLL-DQQLDQELVKRD 142
++EL++++ + E+ Q E+ + +++ ++L ++LE K LL QQL E
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNV----KELKRKLERAKLLLPQQQLQAEADHLG 271
Query: 143 EQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQ--QEGQLELPEQQEGQLELPEQQE 200
++L +L E+ E + +QQE ++ E+ QE + ++ EQ+E ++ EQ+E
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE---KIREQEE 328
Query: 201 GQLELPEQQEGQLELPEQQEGQLELPEQQ--EGQLELPQQQEGQLELSEQQEGQLELSEQ 258
E E+ Q E+ ++E ++ E+ E + ++ +Q+E E E+ Q E+ +
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Query: 259 QEGQLKHLEH----QEGQLEVPEEQMGQLKYLEQ---QEGQLKHLDQQEKQPELPEQQMG 311
+E +++ LE QE E E++ + K EQ QE + K Q+EK E E+
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
Query: 312 QLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVL 371
Q K + +QE K EQ++ + E+ +++ ++ E++ + E + Q+ ++ E+++
Sbjct: 449 QEKKMWRQE--EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 372 QLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLK 431
KQ EK Q + + E+E +++ ++ + + ++++ ++ ++E ++ H ++++ + +
Sbjct: 507 --KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM-HEQEKIWEEE 563
Query: 432 HLEEQEGQLKHLEQQQGQLEVPEQQVG--QPKNLEQEEKQLELPEQQEGQVKHLEKQEAQ 489
+EQE ++ +Q+ ++ E++V + K EQEEK+ E E+ Q + + +QE +
Sbjct: 564 KRQEQEDKMW---RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620
Query: 490 LELPEQQVGQP--KHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAP 547
++ E+++ + K EQ+E E E+ Q + + +QE ++++ E+ + E+
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE----- 675
Query: 548 APGQVQDIQPALPTKGEVLLPVEHQQQKQEVQ-WPPKHK 585
++++ + + + E + E Q+QE + W + K
Sbjct: 676 ---KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 711
Score = 73.9 bits (180), Expect = 4e-13
Identities = 81/374 (21%), Positives = 180/374 (48%), Gaps = 40/374 (10%)
Query: 234 ELPQQQEG-QLELSEQQEGQLELSE-----QQEGQLKHLEHQEGQLEVPE-----EQMGQ 282
EL ++++ LEL EL E Q++ QL E E QL V E E+
Sbjct: 197 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 256
Query: 283 LKYLEQQEGQLKHLDQQ------EKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQL 336
L +Q + + HL ++ + Q ++ E ++ + +Q+E + E+ + E++
Sbjct: 257 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316
Query: 337 EEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHL 396
+EQE +++ E E + QE ++ E+ + + ++ ++Q + +EE+ + +
Sbjct: 317 QEQEEKIREQE------EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 370
Query: 397 VQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQ 456
+ E + K Q+E E++E+ + LE+++ + + + EQE E++Q + ++ EQ+
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEK-IRELEEKMHEQEKIREQE------EKRQEEEKIREQE 423
Query: 457 VGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQ 516
K EQE K E+ Q + + +QE ++ E+++ + + + ++EK E E
Sbjct: 424 ----KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 479
Query: 517 DGQLKHLEQQE-----GQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEH 571
+ K EQ+E ++ + E++ + E+ V+ ++++ + + + E + E
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE-KIREQEEKIREQEEKMWRQEE 538
Query: 572 QQQKQEVQWPPKHK 585
+ ++QE W + K
Sbjct: 539 KIREQEEMWREEEK 552
Score = 49.7 bits (117), Expect = 8e-06
Identities = 42/166 (25%), Positives = 90/166 (54%), Gaps = 14/166 (8%)
Query: 31 QEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQ 90
QE+ +Q Q+ + E +QEEK + + EQE Q++E + E +++
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 91 HWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKE 150
EQ E+ Q+ E E +QE+ R+Q+ K E+E+K+ +Q ++ + +++E++ ++E
Sbjct: 656 MCEQEEKMQEQE--ETMWRQEEKIREQE-KKIREQEEKIREQ--EEMMQEQEEKMWEQEE 710
Query: 151 QLLELPEQQEGHLKHLEQQEGQLKHPEQQ--EGQLELPEQQEGQLE 194
++ E E+ +++QE +++ E++ E ++ L +Q+E E
Sbjct: 711 KMCEQEEK-------MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 118 bits (296), Expect = 1e-26
Identities = 115/468 (24%), Positives = 240/468 (51%), Gaps = 49/468 (10%)
Query: 72 EQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNK-------QLE 124
+++ + + E E +L + ++ E K P+QQL+ E ++L Q+E
Sbjct: 288 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 347
Query: 125 EEK--KLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ--E 180
E + L+QQ ++++ +++E++ +E++ E E+ + + +QE +++ E+ E
Sbjct: 348 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 407
Query: 181 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQL-ELPEQQEGQLELPEQQEGQLELPQQQ 239
+ ++ Q+E E E+ Q E+ ++E ++ EL E+ Q ++ EQ+E + Q++
Sbjct: 408 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR----QEE 463
Query: 240 EGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQ 299
E E ++QE + ++ Q+E + QE ++ EE+M + Q + + +Q
Sbjct: 464 EKIREQEKRQEQEAKMWRQEE----KIREQEEKIREQEEKMWR---------QEEKIHEQ 510
Query: 300 EKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQ 359
EK E E++ + + + +QE + + E+ Q E++ EQE +++ E++ + E H
Sbjct: 511 EKIRE--EEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD 568
Query: 360 EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQ--QEGQLKHLVQQEGQLEQQE 417
+ + + EQ+ +Q EK + Q + + E+E +++ + QE + K Q+E EQ+E
Sbjct: 569 QEEK-IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 418 RQVEHLEQQVGQLKHLEEQEGQLKHLEQQ-QGQLEVPEQQVGQPKNLEQEEKQLELPEQQ 476
+ E E+ Q + + EQE +++ E++ + Q E+ ++Q + K EQEEK E E+
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ--EEKMWEQEEKMCEQEEKM 685
Query: 477 EGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLE 524
+ Q + + +QE ++ E ++ Q Q+EK EH +HLE
Sbjct: 686 QEQEEKMRRQEEKMWEQEVRLRQ-----QEEKMQEH-------QEHLE 721
Score = 116 bits (291), Expect = 5e-26
Identities = 112/468 (23%), Positives = 236/468 (50%), Gaps = 51/468 (10%)
Query: 84 EQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLL-DQQLDQELVKRD 142
++EL++++ + E+ Q E+ + +++ ++L ++LE K LL QQL E
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNV----KELKRKLERAKLLLPQQQLQAEADHLG 332
Query: 143 EQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQ--QEGQLELPEQQEGQLELPEQQE 200
++L +L E+ E + +QQE ++ E+ QE + ++ EQ+E ++ EQ+E
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE---KIREQEE 389
Query: 201 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQE 260
E E+ Q E+ ++E ++ E+ + E +++ ++ + E++E EL E+
Sbjct: 390 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM-MWEKEEKIRELEEKMH 448
Query: 261 GQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQL-----KHLDQQEKQPELPEQQMGQLKH 315
Q K E +E + E EE++ + + ++QE ++ K +Q+EK E E+ Q +
Sbjct: 449 EQEKIREQEEKRQE--EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEK 506
Query: 316 LEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQ 375
+ +QE + ++QE E++ QE +++ E+ Q E + QE ++ E+++ +Q
Sbjct: 507 IHEQEKIREEEKRQEQ--EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW--RQ 562
Query: 376 LEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEE 435
EK Q + + E+E + + +QE ++ +QE ++ E+++ E
Sbjct: 563 EEKMHDQEEKIREQE-------------EKVWRQEEKIREQEEKIREQEEKI------RE 603
Query: 436 QEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQ 495
QE + E++ G+ E K EQEEK E E+ Q + + +QE ++ E+
Sbjct: 604 QEEMTQEQEEKMGEQE--------EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Query: 496 QVGQPKHL--EQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLE 541
++ + + + EQ+EK E E+ Q + +++QE +++ E++ + E
Sbjct: 656 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Score = 109 bits (273), Expect = 6e-24
Identities = 113/426 (26%), Positives = 217/426 (50%), Gaps = 58/426 (13%)
Query: 50 ELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLK 109
EL + +QEEK + + E E + Q++E + +E +++ EQ E+ ++ E + K
Sbjct: 350 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE-K 408
Query: 110 QEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQ 169
+EK +R +++ + EE+ + +++E + K+E++ EL E+ K EQ+
Sbjct: 409 EEKMRRQEEMMWEKEEKMR-----------RQEEMMWEKEEKIRELEEKMHEQEKIREQE 457
Query: 170 EGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ 229
E + +++E E ++QE + ++ Q+E ++ EQ+E E E+ Q E +Q
Sbjct: 458 EKR----QEEEKIREQEKRQEQEAKMWRQEE---KIREQEEKIREQEEKMWRQEEKIHEQ 510
Query: 230 EGQLELPQQQEGQLELSEQQEGQLELSEQQE--GQLKHLEHQEGQLEVPEEQMGQLKYLE 287
E E ++QE Q E+ Q+E ++ EQ+E Q + + QE ++ EE+M +
Sbjct: 511 EKIREEEKRQE-QEEMWRQEE---KIREQEEIWRQKEKIHEQEEKIRKQEEKMWR----- 561
Query: 288 QQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEE--QEGQLKH 345
Q+E K DQ+EK E E+ Q + + +QE + + +QE ++ + EE QE + K
Sbjct: 562 QEE---KMHDQEEKIREQEEKVWRQEEKIREQE---EKIREQEEKIREQEEMTQEQEEKM 615
Query: 346 LEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKH 405
EQ+E E E + EQ+ +Q EK + Q K + E+E +++
Sbjct: 616 GEQEEKMCEQEEKMQ------EQEEKMRRQEEKIREQEKKIREQEEKIRE---------- 659
Query: 406 LVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQ 465
Q+E EQ+E+ E E+ Q + ++EQE +++ E++ + EV +Q Q + +++
Sbjct: 660 --QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ--QEEKMQE 715
Query: 466 EEKQLE 471
++ LE
Sbjct: 716 HQEHLE 721
Score = 79.3 bits (194), Expect = 9e-15
Identities = 112/519 (21%), Positives = 235/519 (45%), Gaps = 69/519 (13%)
Query: 72 EQECEQQQKEPQEQELQQQ-HWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLL 130
EQ+ Q +E +EL+ Q H + QK E Q Q KQLE E + L
Sbjct: 171 EQKASHQHQEALRRELEAQVHTIRILTCQKTE------LQMALYYSQHAVKQLEGEARDL 224
Query: 131 DQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQE 190
+L + G ++ L + Q++ +++E+ E+ LEL
Sbjct: 225 ISRLHDSW----KFAGELEQALSAVATQKKKADRYIEELT-----KERDALSLELYRNTI 275
Query: 191 GQLELPEQQ---EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSE 247
EL E+ + +L+L E ++ +++L ++ + + + +L LPQQQ
Sbjct: 276 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKR----KLERAKLLLPQQQ-------- 323
Query: 248 QQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPE 307
L + + K L+ +L+ E+ L QQ+ + K Q+EK E E
Sbjct: 324 -------LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE-KMWRQEEKIQEWEE 375
Query: 308 QQMGQLKHLEQQEGQPKHLEQQEGQLEQL--EEQEGQLKHLEQQEGQLEHLEHQEGQLGL 365
+ Q + + +QE + + E++ + E++ E++E + E + E + QE +
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435
Query: 366 PEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQ 425
E+++ +L+ EK Q K E+EE + Q+E ++ +QE++ E +
Sbjct: 436 KEEKIRELE--EKMHEQEKIREQEEKR---------------QEEEKIREQEKRQEQEAK 478
Query: 426 QVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPE--QQEGQVKHL 483
Q + + EQE +++ E++ + E+++ + + + +EEK+ E E +QE +++
Sbjct: 479 MWRQEEKIREQEEKIREQEEKMWR---QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 535
Query: 484 E---KQEAQLELPEQQV--GQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKG 538
E +Q+ ++ E+++ + K Q+EK + E+ Q + + +QE ++++ E++
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595
Query: 539 QLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQE 577
+ E+ + Q+ + + + E + E + Q+QE
Sbjct: 596 EQEEKI-REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633
Score = 60.8 bits (146), Expect = 3e-09
Identities = 44/191 (23%), Positives = 102/191 (53%), Gaps = 9/191 (4%)
Query: 45 QKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENP 104
QK + E KQEEK + + +QE ++ QE+++ +Q + E+ +K
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQE---EKIREQEEKVWRQEEKIREQEEKIREQ 597
Query: 105 EQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLK 164
E+++++++ +Q K E+E+K+ +Q ++++ +++E++ ++E++ E ++ +
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQ--EEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Query: 165 HLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ--EGQLELPEQQEGQ 222
+ +QE ++ EQ+E E E+ Q E ++QE ++ E++ E ++ L +Q+E
Sbjct: 656 KIREQEEMMQ--EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Query: 223 LELPEQQEGQL 233
E E E +
Sbjct: 714 QEHQEHLEAAI 724
Score = 60.5 bits (145), Expect = 4e-09
Identities = 77/369 (20%), Positives = 164/369 (44%), Gaps = 78/369 (21%)
Query: 234 ELPQQQEG-QLELSEQQEGQLELSE-----QQEGQLKHLEHQEGQLEVPE-----EQMGQ 282
EL ++++ LEL EL E Q++ QL E E QL V E E+
Sbjct: 258 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 317
Query: 283 LKYLEQQEGQLKHLDQQ------EKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQL 336
L +Q + + HL ++ + Q ++ E ++ + +Q+E + E+ + E++
Sbjct: 318 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 377
Query: 337 EEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHL 396
+EQE +++ E E + QE ++ E+ + + + EK + Q + + E+E +++
Sbjct: 378 QEQEEKIREQE------EKIREQEEKMRRQEEMMWEKE--EKMRRQEEMMWEKEEKMR-- 427
Query: 397 VQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQ 456
+QE + ++E ++ LE+++ + + + EQE E++Q + ++ EQ+
Sbjct: 428 -----------RQEEMMWEKEEKIRELEEKMHEQEKIREQE------EKRQEEEKIREQE 470
Query: 457 VGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQ 516
K EQE K E+ Q + + +QE ++ E+++ + + + ++EK E E
Sbjct: 471 ----KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW 526
Query: 517 DGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQ 576
+ K EQ+E + +QK ++ + E ++++
Sbjct: 527 RQEEKIREQEE-----IWRQKEKIHEQE-------------------------EKIRKQE 556
Query: 577 EVQWPPKHK 585
E W + K
Sbjct: 557 EKMWRQEEK 565
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 117 bits (293), Expect = 3e-26
Identities = 113/485 (23%), Positives = 242/485 (49%), Gaps = 43/485 (8%)
Query: 95 HEEYQKAENPEQQLKQEKTQRDQ--QLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQL 152
H+ ++ A EQ L TQ+ + + ++L +E+ L +L + + DE+L K +L
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT-DEELKEKNAKL 226
Query: 153 LELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQ-------------------EGQL 193
E + E ++ +LK + + +L LP+QQ + Q+
Sbjct: 227 QEKLQLVESEKSEIQLNVKELKR-KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 194 E-------LPEQQEGQLELPEQ--QEGQLELPEQQEGQLELPEQ-QEGQLELPQQQEGQL 243
E L +QQE ++ E+ QE + ++ EQ+E E E+ +E + ++ +Q+E
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Query: 244 ELSEQQEGQLELSEQQEGQLKHLEH----QEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQ 299
E E+ Q E+ ++E +++ LE +E ++ EE+M + + + +QE + + ++
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 405
Query: 300 EKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQ 359
+Q + EQ+ + E+ Q + + +QE ++ + EE+ + + + ++E + E E
Sbjct: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
Query: 360 EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQ 419
+ + EQ+ + +Q EK Q K ++EE + + Q + + +QE ++ +QE +
Sbjct: 466 RQEEKIREQEEIW-RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEK 524
Query: 420 VEHLEQQVG-QLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEG 478
+ E+++ Q + + EQE ++ E++ G+ E Q+ Q K QEEK E E+
Sbjct: 525 IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE--QEKMRRQEEKIREQEEKIRE 582
Query: 479 QVKHLEKQEAQLELPEQQVGQPKHL--EQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQ 536
Q + + +QE ++ E+++ + + + EQ+EK E E+ Q + +++QE +++ E++
Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 537 KGQLE 541
+ E
Sbjct: 643 MWEQE 647
Score = 114 bits (284), Expect = 3e-25
Identities = 96/459 (20%), Positives = 239/459 (52%), Gaps = 39/459 (8%)
Query: 72 EQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNK-------QLE 124
+++ + + E E +L + ++ E K P+QQL+ E ++L Q+E
Sbjct: 227 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286
Query: 125 EEK--KLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ--E 180
E + L+QQ ++++ +++E++ +E++ E E+ + + +QE +++ E+ E
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 346
Query: 181 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQL-ELPEQQEGQLELPEQQEGQLELPQQQ 239
+ ++ Q+E E E+ E+ ++E ++ EL E+ Q ++ EQ+E + Q++
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKR----QEE 402
Query: 240 EGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQ 299
E E ++QE + ++ Q+E + QE ++ E++M + + ++ +++ +++
Sbjct: 403 EKIREQEKRQEQEAKMWRQEE----KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458
Query: 300 EKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQ 359
++Q E+ Q+ + + +QE + E+ Q + +++E + E+ Q E + Q
Sbjct: 459 QEQEEMWRQE----EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQ 514
Query: 360 EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQ 419
E ++ E+++ + Q EK + Q + + E+E ++ ++ G+ + +Q++ ++ +QE +
Sbjct: 515 EEKMWRQEEKIRE--QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK 572
Query: 420 VEHLEQQVGQLKH-LEEQEGQL----KHLEQQQGQLEVPEQQVGQP--KNLEQEEKQLEL 472
+ E+++ + K + EQE ++ + + +Q+ ++ E+++ + K EQEEK E
Sbjct: 573 IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632
Query: 473 PEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLE 511
E+ Q + + +QE +L E++ +++ ++HLE
Sbjct: 633 EEKMRRQEEKMWEQEVRLRQQEEK------MQEHQEHLE 665
Score = 113 bits (283), Expect = 4e-25
Identities = 115/464 (24%), Positives = 243/464 (52%), Gaps = 34/464 (7%)
Query: 84 EQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLL-DQQLDQELVKRD 142
++EL++++ + E+ Q E+ + +++ ++L ++LE K LL QQL E
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNV----KELKRKLERAKLLLPQQQLQAEADHLG 271
Query: 143 EQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQ--QEGQLELPEQQEGQLELPEQQE 200
++L +L E+ E + +QQE ++ E+ QE + ++ EQ+E ++ EQ+E
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE---KIREQEE 328
Query: 201 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQE 260
E E+ Q E+ ++E ++ E+ + E ++ ++ + E++E EL E+
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM-MWEKEEKIRELEEKMH 387
Query: 261 GQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQ--EKQPELPEQQMGQLKHLEQ 318
Q K E +E + E EE++ + + ++QE ++ +++ E++ ++ EQ+ + E+
Sbjct: 388 EQEKIREQEEKRQE--EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 445
Query: 319 QEGQPKHLEQQEGQ-LEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLE 377
Q K E+++ Q E++ QE +++ E+ Q E + QE + +Q+ +Q E
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK---IRKQEEKVWRQEE 502
Query: 378 KQQGQPKHLEEEEGQL----KHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVG-QLKH 432
K Q + + E+E ++ + + +QE +++ +QE ++ +QE ++ E+++G Q +
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIR---EQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 433 LEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLEL 492
++EQE + E+ + Q E +Q + K EQEEK E E+ Q + +++QE ++
Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQ--KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE 617
Query: 493 PEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQ 536
E+ K EQ+EK E E+ Q + + +QE +L+ E++
Sbjct: 618 QEE-----KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
Score = 108 bits (270), Expect = 1e-23
Identities = 109/423 (25%), Positives = 220/423 (52%), Gaps = 47/423 (11%)
Query: 50 ELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLK 109
EL + +QEEK + + E E + Q++E + +E +++ EQ E+ ++ E + K
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE-K 347
Query: 110 QEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQ 169
+EK +R +++ + EE+ + L +E + K+E++ EL E+ K EQ+
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRL-----------EEMMWEKEEKIRELEEKMHEQEKIREQE 396
Query: 170 EGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ 229
E + +++E E ++QE + ++ Q+E ++ EQ+E E ++ Q E +Q
Sbjct: 397 EKR----QEEEKIREQEKRQEQEAKMWRQEE---KIREQEEKIREQEKKMWRQEEKIHEQ 449
Query: 230 EGQLELPQQQEGQLELSEQQEGQLELSEQQE-GQLKHLEHQEGQLEVPEEQMGQLKYLEQ 288
E E ++QE Q E+ Q+E ++ EQ+E + K H++ ++ EE K Q
Sbjct: 450 EKIREEEKRQE-QEEMWRQEE---KIREQEEIWRQKEKMHEQEKIRKQEE-----KVWRQ 500
Query: 289 QEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQ 348
+E K DQ+EK E E+ Q + + +QE E+ Q E++ EQE ++ E+
Sbjct: 501 EE---KMHDQEEKIREQEEKMWRQEEKIREQE------EKIREQEEKIREQEEMMQEQEE 551
Query: 349 QEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQ 408
+ G+ E ++ ++ E+++ + Q EK + Q + + E+E + + +QE +++ Q
Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIRE--QEEKIREQKEKIREQE---EKIWEQEEKIRE--Q 604
Query: 409 QEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEK 468
+E EQ+E+ E E+ Q + ++EQE +++ E++ + EV +Q Q + +++ ++
Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ--QEEKMQEHQE 662
Query: 469 QLE 471
LE
Sbjct: 663 HLE 665
Score = 103 bits (256), Expect = 6e-22
Identities = 100/384 (26%), Positives = 209/384 (54%), Gaps = 33/384 (8%)
Query: 58 KQEEKHMTAVKGLPEQE---CEQQQK-EPQEQELQQQH---WEQHEEYQKAENPEQQLKQ 110
+QEEK + + EQE EQ++K QE+++++Q WE+ E+ ++ E + K+
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE-KE 362
Query: 111 EKTQRDQQLNKQLEEEKKLLDQQL-DQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQ 169
EK +R +++ + EE+ + L++++ +QE ++ E+ ++E++ E ++QE K Q+
Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 170 EGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ 229
E K EQ+E E ++ Q E +QE E ++QE Q E+ Q+E ++ EQ+
Sbjct: 423 E---KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE-QEEMWRQEE---KIREQE 475
Query: 230 EGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMG-QLKYLEQ 288
E + + E Q ++ +Q+E E+ Q + + QE ++ EE++ Q + + +
Sbjct: 476 EIWRQKEKMHE-QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE 534
Query: 289 QEGQLKHLDQQEKQPELPEQQMG-QLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLE 347
QE +++ +QE+ + E++MG Q + +++QE + E+ Q E++ EQ+ +++ E
Sbjct: 535 QEEKIR---EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE 591
Query: 348 QQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLV 407
++ + E ++ ++ + EQ+ +Q EK Q + ++E+E +++ Q + +
Sbjct: 592 EKIWEQEEKIREQEEM-MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR------QEEKMW 644
Query: 408 QQEGQLEQQERQV----EHLEQQV 427
+QE +L QQE ++ EHLE +
Sbjct: 645 EQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 70.9 bits (172), Expect = 3e-12
Identities = 60/230 (26%), Positives = 123/230 (53%), Gaps = 25/230 (10%)
Query: 54 EVPSKQEEKHM-TAVKGLPEQECEQQQKE---------PQEQELQQQHWEQHEEYQKAEN 103
E +QE++ M + + EQE +QKE QE+++ +Q + H++ +K
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513
Query: 104 PEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHL 163
E+++ +++ + +Q K E+E+K+ +Q ++ + +++E++G ++E++ E + +
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQ--EEMMQEQEEKMGEQEEKMQEQEKMRRQEE 571
Query: 164 KHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL 223
K EQ+E K EQ+E ++ EQ+E E E+ Q E+ ++QE ++ EQ+E
Sbjct: 572 KIREQEE---KIREQKE---KIREQEEKIWEQEEKIREQEEMMQEQEEKMW--EQEEKMC 623
Query: 224 ELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQL 273
E E+ + Q E ++QE + E ++ L +Q+E +H EH E +
Sbjct: 624 EQEEKMQEQEEKMRRQE-----EKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 30.8 bits (68), Expect = 3.6
Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 10/110 (9%)
Query: 17 QELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECE 76
QE ++ + +E++++ QK + E +QEEK + + EQE +
Sbjct: 563 QEKMRRQEEKIREQEEKIRE--------QKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
Query: 77 QQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEE 126
++E + E +++ EQ E+ ++ E E+ +QE R Q+ Q +E
Sbjct: 615 MWEQEEKMCEQEEKMQEQEEKMRRQE--EKMWEQEVRLRQQEEKMQEHQE 662
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 111 bits (277), Expect = 2e-24
Identities = 116/431 (26%), Positives = 226/431 (52%), Gaps = 29/431 (6%)
Query: 95 HEEYQKAENPEQQLKQEKTQRDQ--QLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQL 152
H+ ++ A EQ L TQ+ + + ++L +E+ L +L + + DE+L K +L
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT-DEELKEKNAKL 214
Query: 153 LELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQ---EGQLELPEQQEGQLELPEQ- 208
E + E ++ +LK + + +L LP+QQ E E Q +L Q
Sbjct: 215 QEKLQLVESEKSEIQLNVKELKR-KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 209 QEGQL--ELPEQQEGQLELPEQ--QEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLK 264
+E +L L +QQE ++ E+ QE + ++ +Q+E E E+ Q E+ ++E +++
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR 333
Query: 265 HLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPK 324
QE + EE++ +L+ E+ Q K +Q+EK+ E E+ Q K EQ+ +
Sbjct: 334 R---QEEMMWEKEEKIRELE--EKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWR 387
Query: 325 HLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPK 384
E+ Q E++ EQE ++ E++ G+ E + E + + EQ+ +Q EK + Q K
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEE-KMWEQEEEMQEQEEKMRRQEEKIREQEK 446
Query: 385 HLEEEEGQLKHLVQQ-EGQLKHLVQQEGQLEQQERQVEHLEQQVG-QLKHLEEQEGQLKH 442
+ E+E +++ + + Q + + +QEG++ +QE +++ E+++ Q + + EQE +++
Sbjct: 447 KIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE 506
Query: 443 LEQQ-QGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPK 501
E++ + Q E+ ++Q + K EQEEK E E+ + Q + + +QE ++ EQ+V +
Sbjct: 507 QEEKIREQEEMMQEQ--EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR--EQEV---R 559
Query: 502 HLEQQEKHLEH 512
+Q+EK EH
Sbjct: 560 LRQQEEKMQEH 570
Score = 103 bits (257), Expect = 4e-22
Identities = 111/489 (22%), Positives = 233/489 (47%), Gaps = 48/489 (9%)
Query: 72 EQECEQQQKEPQEQELQQQHWE------QHEEYQKAENPEQQLKQEKTQRDQQLNKQLEE 125
EQ+ Q +E +EL+ Q Q E Q A Q ++ + L +L +
Sbjct: 98 EQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 157
Query: 126 EKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLEL 185
K + L+Q L Q + EL ++++ LE + E +E +L
Sbjct: 158 SWKFAGE-LEQALSAVATQKKKADRYIEELTKERDA--LSLELYRNTITDEELKEKNAKL 214
Query: 186 PEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLEL 245
E+ L+L E ++ +++L + EL + E L QQ+ Q E + +
Sbjct: 215 QEK----LQLVESEKSEIQLNVK-----ELKRKLERAKLLLPQQQLQAEADHLGKELQSV 265
Query: 246 SEQQEGQLE-------LSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQ 298
S + + Q+E L++QQE + + QE +++ EE++ QE + K +Q
Sbjct: 266 SAKLQAQVEENELWNRLNQQQE---EKMWRQEEKIQEREEKI--------QEQEEKIREQ 314
Query: 299 QEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEH 358
+EK E + + + +QE E++ +LE+ ++ +++ E++ + E +
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 374
Query: 359 QEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEG-QLKHLVQQEGQLEQQE 417
QE + EQ+ +Q EK + Q + + E+E ++ ++ G Q + + +QE ++++QE
Sbjct: 375 QEKR---QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431
Query: 418 RQVEHLEQQV-GQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQP--KNLEQEEKQLELPE 474
++ E+++ Q K + EQE +++ +Q+ ++ E+++G+ K EQE K E E
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIR---EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Query: 475 QQEGQVKHLEKQEAQLELPEQQVGQPKHL--EQQEKHLEHPEQQDGQLKHLEQQEGQLKD 532
+ Q + + +QE ++ E+++ + + + EQ+EK E E+ Q + +++QE +++
Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548
Query: 533 LEQQKGQLE 541
E++ + E
Sbjct: 549 QEEKMREQE 557
Score = 98.6 bits (244), Expect = 1e-20
Identities = 85/337 (25%), Positives = 179/337 (53%), Gaps = 27/337 (8%)
Query: 31 QEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQE--LQ 88
Q+ + L Q V +L +V +E + + E++ +Q+++ QE+E +Q
Sbjct: 249 QQLQAEADHLGKELQSVSAKLQAQV---EENELWNRLNQQQEEKMWRQEEKIQEREEKIQ 305
Query: 89 QQHWEQHEEYQKAENPEQQL--KQEKTQRDQQLNKQLEEEKKLLDQQL-DQELVKRDEQL 145
+Q + E+ +K E+ + K+EK +R +++ + EE+ + L++++ +QE ++ E+
Sbjct: 306 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 365
Query: 146 GMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLEL 205
++E++ E ++QE K Q+E + E+ Q E+ ++QE ++ EQ+E E
Sbjct: 366 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG--EQEEKMWEQ 423
Query: 206 PEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQL-- 263
E+ + Q E +QE ++ +E + ++ +Q+E E E + Q E +QEG++
Sbjct: 424 EEEMQEQEEKMRRQEEKI-----REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Query: 264 --KHLEHQEGQLEVPEEQMG-QLKYLEQQEGQLKHLDQ--QEKQPELPEQQMGQLKHLEQ 318
++ QE ++ EE++ Q K + +QE +++ ++ QE++ ++ EQ+ K EQ
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE---KMCEQ 535
Query: 319 QEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEH 355
+E + E+ Q E++ EQE +L+ +Q+E EH
Sbjct: 536 EEKMQEQEEKMRRQEEKMREQEVRLR--QQEEKMQEH 570
Score = 97.8 bits (242), Expect = 2e-20
Identities = 82/322 (25%), Positives = 167/322 (51%), Gaps = 29/322 (9%)
Query: 79 QKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQL---D 135
Q + +E EL + +Q EE + + Q ++EK Q ++ ++ EE+ + ++ + +
Sbjct: 270 QAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE 329
Query: 136 QELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLEL 195
+++ +++E + K+E++ EL E+ K EQ+E + +++E E ++QE + ++
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR----QEEEKIREQEKRQEQEAKM 385
Query: 196 PEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLEL 255
Q+E E E+ Q E+ ++QE ++ EQ+E E ++ + Q E +QE ++
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMG--EQEEKMWEQEEEMQEQEEKMRRQEEKIRE 443
Query: 256 SEQQ-EGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLK 314
E++ Q + + QE ++ EE+MG+ QEG++ +Q+ K E E+ Q +
Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGE------QEGKM--CEQEAKMQEQEEKMRRQEE 495
Query: 315 HLEQQEGQPKHLEQQEGQLEQLEE--QEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQ 372
+ +QE K + +QE ++ + EE QE + K EQ+E E E + EQ+
Sbjct: 496 KIREQE---KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ------EQEEKM 546
Query: 373 LKQLEKQQGQPKHLEEEEGQLK 394
+Q EK + Q L ++E +++
Sbjct: 547 RRQEEKMREQEVRLRQQEEKMQ 568
Score = 86.3 bits (212), Expect = 7e-17
Identities = 117/495 (23%), Positives = 237/495 (47%), Gaps = 42/495 (8%)
Query: 96 EEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQL--DQELVKRDEQLGMKKEQLL 153
E+ QKA + Q+ + + + Q + L +K L L Q VK QL + L+
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVK---QLEGEARDLI 152
Query: 154 ELPEQQEGHLKHLEQQEGQLKHPEQQEGQL--ELPEQQEG-QLELPEQQEGQLELPEQQE 210
LEQ + +++ + EL ++++ LEL EL E+
Sbjct: 153 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 212
Query: 211 GQLELPEQQEGQLELPEQQEGQLELPQQQ-EGQLELSEQQEGQLELSEQQEGQLKHLEHQ 269
E +L+L E ++ +++L ++ + +LE ++ Q +L + + K L+
Sbjct: 213 KLQE-------KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 265
Query: 270 EGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQ 329
+L+ E+ L QQ+ + K Q+EK E E+ Q + + +QE K Q+
Sbjct: 266 SAKLQAQVEENELWNRLNQQQEE-KMWRQEEKIQEREEKIQEQEEKIREQE--EKMRRQE 322
Query: 330 EGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEE 389
E E+ E+ Q + + ++E ++ LE + + EQ+ ++ +Q EK+Q + K E+E
Sbjct: 323 EMMWEKEEKMRRQEEMMWEKEEKIRELEEK-----MHEQEKIR-EQEEKRQEEEKIREQE 376
Query: 390 EGQLKH--LVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVG-QLKHLEEQEGQLKHLEQQ 446
+ Q + + +QE +++ +QE ++ +QE ++ E+++G Q + + EQE +++ E++
Sbjct: 377 KRQEQEAKMWRQEEKIR---EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK 433
Query: 447 QGQLE--VPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLE 504
+ E + EQ + K EQEEK E E + Q + + +QE ++ EQ+ K E
Sbjct: 434 MRRQEEKIREQ---EKKIREQEEKIREQEEMMQEQEEKMGEQEG--KMCEQEA---KMQE 485
Query: 505 QQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGE 564
Q+EK E+ Q K + +QE ++++ E+ + E+ ++ + + + + E
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ-EEKMQEQEE 544
Query: 565 VLLPVEHQQQKQEVQ 579
+ E + ++QEV+
Sbjct: 545 KMRRQEEKMREQEVR 559
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 110 bits (275), Expect = 4e-24
Identities = 124/457 (27%), Positives = 240/457 (52%), Gaps = 46/457 (10%)
Query: 90 QHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKK 149
+HW Q EE +K E + + + E+ ++ + EE KK ++ +Q ++ + G +K
Sbjct: 667 EHW-QDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQ----KEREQGHQK 721
Query: 150 EQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ 209
E+ E+ E E E++EG + E++EG E E+ EG E+ EG+ E E +
Sbjct: 722 ERNQEMEEGGEEEHGEGEEEEGDREEEEEKEG--EGKEEGEG-----EEVEGEREKEEGE 774
Query: 210 EGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQ 269
+ E ++E E +Q EG+ E + EG+ E +++ G++E E +EG+ + E +
Sbjct: 775 RKKEERAGKEEKGEEEGDQGEGEEE---ETEGRGE-EKEEGGEVEGGEVEEGKGEREEEE 830
Query: 270 EGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQ 329
E EE G E++EG+ + + + K E E+ G+ + E+ EG+ E++
Sbjct: 831 EEGEGEEEEGEG-----EEEEGEGEEEEGEGKGEEEGEEGEGE-EEGEEGEGEG---EEE 881
Query: 330 EGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEE 389
EG+ E EE EG+ E++EG+ E E EG+ E + ++ E+ +G+ EEE
Sbjct: 882 EGEGEGEEEGEGEG---EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG---EEE 935
Query: 390 EGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQ 449
EG+ + EG+ + ++EG+ E +E + E ++ G+ + EE EG+ + E+ +G+
Sbjct: 936 EGEGEG-EDGEGEGE---EEEGEWEGEEEEGEGEGEEEGEGEG-EEGEGEGEE-EEGEGE 989
Query: 450 LEVPE-QQVGQPKNLEQEEKQLELPEQQEGQVK-HLEKQEAQLELPE---QQVGQPKHL- 503
E E ++ G+ + +EE + E E++EG+V+ +E +E + E E ++ G+ +
Sbjct: 990 GEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049
Query: 504 ---EQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQK 537
E+ ++ E E+++G+ + ++E + +D E+ K
Sbjct: 1050 GEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYK 1086
Score = 107 bits (266), Expect = 4e-23
Identities = 120/465 (25%), Positives = 248/465 (53%), Gaps = 34/465 (7%)
Query: 49 VELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQL 108
+E P E + EK + EQE +++++ Q++ Q+ EE+ + E E
Sbjct: 686 MERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD- 744
Query: 109 KQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQ 168
++E+ +++ + ++ E E+ +++ ++ K++E+ G K+E+ E +Q EG E+
Sbjct: 745 REEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAG-KEEKGEEEGDQGEG-----EE 798
Query: 169 QEGQLKHPEQQE-GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPE 227
+E + + E++E G++E E +EG+ E E++E E+ EG+ E E +E + E
Sbjct: 799 EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKG 858
Query: 228 QQEGQLELPQQ--QEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKY 285
++EG+ ++ +EG+ E E++EG+ E E+ EG+ E +EG+ E EE G+
Sbjct: 859 EEEGEEGEGEEEGEEGEGE-GEEEEGEGEGEEEGEGE---GEEEEGEGEGEEEGEGE--- 911
Query: 286 LEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKH 345
E++EG+ K ++ E+ E++ G+ + E EG+ E++EG+ E EE+EG+ +
Sbjct: 912 GEEEEGEGKGEEEGEEGEGEGEEEEGEGEG-EDGEGEG---EEEEGEWEG-EEEEGEGEG 966
Query: 346 LEQQEGQLEHLEHQ-EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLK 404
E+ EG+ E E + E + G E + ++ +++G+ + EEEG+ + ++EG+++
Sbjct: 967 EEEGEGEGEEGEGEGEEEEGEGEGE----EEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022
Query: 405 HLVQ-QEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNL 463
V+ +EG+ E +E + E ++ + EE + E+++G+ Q+ G+ +N
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKY----QETGEEENE 1078
Query: 464 EQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEK 508
Q+ ++ + + +G VK+ + + Q + G K EQ+ K
Sbjct: 1079 RQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGK--EQRSK 1121
Score = 100 bits (248), Expect = 5e-21
Identities = 121/532 (22%), Positives = 256/532 (48%), Gaps = 50/532 (9%)
Query: 52 PVEVPSKQ----EEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQH-------EEYQK 100
PV+ KQ E TA+ + + ++ E +E + +QH Q +
Sbjct: 519 PVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEA 578
Query: 101 AENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQE 160
+ E ++ +EK + +EE++ +++ + R E+ + + L + E E
Sbjct: 579 FSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSE 638
Query: 161 GHLKHLEQ-------------QEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPE 207
G K + + +EG Q+ + E E+ +G+ E+ EG+ EL E
Sbjct: 639 GKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAE 698
Query: 208 QQEGQLELPEQQEG-QLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHL 266
++E + E+QE + E Q+E E+ + E + E++EG E E++EG+ K
Sbjct: 699 KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEE 758
Query: 267 ---EHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPE------QQMGQLKHLE 317
E EG+ E E + + + ++E + DQ E + E E ++ G+++ E
Sbjct: 759 GEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGE 818
Query: 318 QQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLK-QL 376
+EG+ + E++E + EE EG+ + E +E + E +EG+ G E++ + + +
Sbjct: 819 VEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG 878
Query: 377 EKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQ 436
E+++G+ + EE EG+ + ++EG+ + + EG+ E++E + + E+ EE+
Sbjct: 879 EEEEGEGEGEEEGEGEGE---EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE 935
Query: 437 EGQLK------HLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQL 490
EG+ + E+++G+ E E++ G+ + E+ E + E+ EG+ + E +
Sbjct: 936 EGEGEGEDGEGEGEEEEGEWEGEEEE-GEGEGEEEGEGE---GEEGEGEGEEEEGEGEGE 991
Query: 491 ELPEQQVGQPKHLEQQEKHLEHPEQQDGQLK-HLEQQEGQLKDLEQQKGQLE 541
E ++ G+ + ++E E E+++G+++ +E +EG+ + E+++G+ E
Sbjct: 992 EEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE-GEGEEEEGEEE 1042
Score = 91.7 bits (226), Expect = 2e-18
Identities = 125/541 (23%), Positives = 256/541 (47%), Gaps = 75/541 (13%)
Query: 63 HMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQ 122
+MT + L E + Q+Q+ QQ E ++ EN + +E ++
Sbjct: 501 NMTHIMSLNSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEM------- 553
Query: 123 LEEEKKLLDQQLDQELVKRDEQLGMK--KEQLLELPEQQEG---------HLKHLEQQEG 171
+E K Q + Q + ++ ++ +E+PE++EG + +E E
Sbjct: 554 --KEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEE 611
Query: 172 QLK-HPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ----------QEGQLELPEQQE 220
+K H ++E L + + E+ E + + E +EG Q+
Sbjct: 612 NVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQD 671
Query: 221 GQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQM 280
+ E E+ +G+ E+ + EG+ EL+E++E + E+QE + + HQ+ + + EE
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEG- 730
Query: 281 GQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQ--LKHLEQQEGQPKHLE----------- 327
G+ ++ E +E + +++EK+ E E+ G+ E++EG+ K E
Sbjct: 731 GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790
Query: 328 --QQEGQLEQLE------EQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLK--QLE 377
Q EG+ E+ E E+ G+++ E +EG+ E E +E G E+ + + + E
Sbjct: 791 GDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGE 850
Query: 378 KQQGQPKHLEE-EEGQLKHL--------VQQEGQLKHLVQQEGQLEQQERQVEHLEQQVG 428
+++G+ K EE EEG+ + ++EG+ + + EG+ E++E + E E+ G
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEG 910
Query: 429 QLKHLEEQEGQLKHLEQ-QQGQLEVPEQQ---VGQPKNLEQEEKQLELP-EQQEGQVKHL 483
+ EE+EG+ K E+ ++G+ E E++ G+ E EE++ E E++EG+ +
Sbjct: 911 E---GEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGE 967
Query: 484 EKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQP 543
E+ E + E+ G+ + E + + E +++G+ + ++EG+ + E+++G++E
Sbjct: 968 EEGEGE---GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024
Query: 544 V 544
V
Sbjct: 1025 V 1025
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 106 bits (265), Expect = 5e-23
Identities = 122/468 (26%), Positives = 233/468 (49%), Gaps = 68/468 (14%)
Query: 54 EVPSKQEEKHMTAVKGLPEQECEQQQK----EPQEQELQQQHWEQHEEYQKAEN--PEQQ 107
+ PS + ++ + L E+ E Q+K E ++ E+Q + + ++A+ P+QQ
Sbjct: 200 DAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
Query: 108 LKQEKTQRDQQLNK-------QLEEEK--KLLDQQLDQELVKRDEQLGMKKEQLLELPEQ 158
L+ E + ++L Q+EE + LL+QQ ++++ +++E++ ++E++ E
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE---- 315
Query: 159 QEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ 218
QE LK EQ+E + E+ Q E +QE ++ E++ + EQ+E ++ EQ
Sbjct: 316 QE--LKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK-----IREQEE---KIREQ 365
Query: 219 QEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEE 278
+E E+ Q E Q+QE ++ E++ + EQ+E + + + QE ++ +E
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWRQEEK-----IREQEEKRQEKMWRQEKKMREQDE 420
Query: 279 QMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHL-EQQEGQPKHLEQQEGQLEQLE 337
K EQ+E + Q+EK EL E Q + L E +E + E+ + Q E+++
Sbjct: 421 -----KIREQEEEMWR---QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 338 EQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLV 397
QE +++ E++ + E L QE ++ EQ+ +Q EK Q + ++E+E +++
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIW--EQEEKMWRQEEKMWEQEEKMQEQEEKMQ--- 527
Query: 398 QQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQV 457
+QE +++ +QE +L QQE + ++EQE +L+ LE++ G+L + +
Sbjct: 528 RQEEKMR---EQEVRLWQQEEK-------------MQEQEVRLQELEERLGKLGQKAELL 571
Query: 458 GQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQ 505
G +E LP L+ QEAQ L +QQ HL+Q
Sbjct: 572 G---GAGRESGSQRLPTLTPILQVELKSQEAQ-SLQQQQDHYRGHLQQ 615
Score = 97.8 bits (242), Expect = 2e-20
Identities = 116/506 (22%), Positives = 238/506 (47%), Gaps = 69/506 (13%)
Query: 92 WEQHEEYQKAENPEQQLKQEKTQRDQQLN-----KQLEEEKKLLDQQLDQELVKRDEQLG 146
W + E + PE L +E D + ++L +E+ +L + + DE+L
Sbjct: 159 WLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTIT-DEELK 217
Query: 147 MKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELP 206
K +L E E ++ LK + + QL LP+QQ L++ + G+
Sbjct: 218 EKNAELQEKLRLVESEKSEIQLNVKDLKR-KLERAQLLLPQQQ---LQVEADRLGK---- 269
Query: 207 EQQEGQLELPEQ-QEGQL-ELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQE---G 261
E Q +L Q +E +L L QQ+ + Q+++ Q + + E +L++ EQ+E
Sbjct: 270 ELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR 329
Query: 262 QLKHLEHQEGQLEVPEEQM-GQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQE 320
Q + + QE ++ E++M Q + + +QE +++ +Q+EK E+ Q + +++QE
Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR--EQEEKMWRQEEKIREQDEKIQEQE 387
Query: 321 GQPKHLEQQEGQLEQLEE--QEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEK 378
+ + +QE ++ + EE QE + ++ Q E + QE ++ E+++ +L+++ +
Sbjct: 388 ---EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 379 QQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEG 438
Q EE+ +++ +Q+E + + +QE ++++QE +++ E++ + + L +QE
Sbjct: 445 DQ------EEKLREVEEKMQEEEE--KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496
Query: 439 QLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVG 498
++ E++ + E K EQEEK E E+ + Q + + +QE +L
Sbjct: 497 KIWEQEEKMWRQE--------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRL-------- 540
Query: 499 QPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPA 558
+Q+EK +++QE +L++LE++ G+L Q +
Sbjct: 541 ----WQQEEK--------------MQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR 582
Query: 559 LPTKGEVLLPVEHQQQKQEVQWPPKH 584
LPT +L Q+ Q +Q H
Sbjct: 583 LPTLTPILQVELKSQEAQSLQQQQDH 608
Score = 94.0 bits (232), Expect = 3e-19
Identities = 93/353 (26%), Positives = 187/353 (52%), Gaps = 30/353 (8%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQ 117
+QEEK + + EQE + ++E + +E +++ W Q E K E+++++++ + +
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE---KMHEQEEKIREQEDKMWR 350
Query: 118 QLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPE 177
Q K E+E+K+ +Q ++++ +++E++ +EQ ++ EQ+E + +QE +++ E
Sbjct: 351 QEEKIREQEEKIREQ--EEKMWRQEEKI---REQDEKIQEQEE----EMWRQEEKIR--E 399
Query: 178 QQEGQLELPEQQEGQLELPEQ--QEGQLELPEQQEGQLELPEQQEGQLE-LPEQQEGQLE 234
Q+E + E +QE ++ ++ +E + E+ Q+E EL E + Q E L E +E E
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 235 LPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQM--GQLKYLEQQEGQ 292
++ + Q E ++QE +++ E++ + + L QE ++ EE+M + K EQ+E
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE-- 517
Query: 293 LKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQ 352
K +Q+EK E+ Q L QQE + +++QE +L++LEE+ G+ L Q+
Sbjct: 518 -KMQEQEEKMQRQEEKMREQEVRLWQQE---EKMQEQEVRLQELEERLGK---LGQKAEL 570
Query: 353 LEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEE--EGQLKHLVQQEGQL 403
L + G LP + +L+ Q+ Q +++ G L+ V QL
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Score = 92.0 bits (227), Expect = 1e-18
Identities = 107/400 (26%), Positives = 205/400 (51%), Gaps = 51/400 (12%)
Query: 50 ELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENP--EQQ 107
+L VE +E + K L Q E + Q+ +++ W Q E+ Q+ E EQ+
Sbjct: 259 QLQVEADRLGKELQSVSAK-LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE 317
Query: 108 LK----QEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHL 163
LK +EK R ++ K E+E+K+ +Q+ ++ +++E++ ++E++ E E+
Sbjct: 318 LKIREQEEKMWRQEE--KMHEQEEKIREQE--DKMWRQEEKIREQEEKIREQEEKMWRQE 373
Query: 164 KHLEQQEGQLKHPEQQEGQLE--LPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEG 221
+ + +Q+ +++ E++ + E + EQ+E + E +QE ++ EQ E ++ EQ+E
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR--EQDE---KIREQEE- 427
Query: 222 QLELPEQQEGQLELPQQQEGQLE-LSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQM 280
E+ Q+E EL + + Q E L E +E E E+ + Q + ++ QE +++ EE+
Sbjct: 428 --EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT 485
Query: 281 G-QLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQ 339
Q K L+Q+E K +Q+EK E+ Q + +++QE + +++QE E++ EQ
Sbjct: 486 WRQEKLLKQEE---KIWEQEEKMWRQEEKMWEQEEKMQEQE---EKMQRQE---EKMREQ 536
Query: 340 EGQL----KHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKH 395
E +L + +++QE +L+ LE + G+LG Q+ L ++ G + L
Sbjct: 537 EVRLWQQEEKMQEQEVRLQELEERLGKLG---QKAELLGGAGRESG-----SQRLPTLTP 588
Query: 396 LVQQEGQLKHLVQQEGQ--LEQQERQVEHLEQQVGQLKHL 433
++Q E L QE Q +QQ+ HL+Q V + L
Sbjct: 589 ILQVE-----LKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Score = 80.5 bits (197), Expect = 4e-15
Identities = 78/317 (24%), Positives = 158/317 (49%), Gaps = 34/317 (10%)
Query: 45 QKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQK---- 100
Q++ + E +QEEK + + EQE + ++E + +E +++ EQ E+ +
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 101 --------AENPEQQLKQEKTQRDQQLNKQ---LEEEKKLLDQQLDQELVKRDEQLGMKK 149
E E+ +QE+ R+Q+ +Q +EKK+ +Q D+++ +++E++ ++
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ--DEKIREQEEEMWRQE 433
Query: 150 EQLLELPEQQEGHLKHLEQQEGQLKHPEQ--QEGQLELPEQQEGQLELPEQQEGQLELPE 207
E++ EL E + + L + E +++ E+ QE + ++ Q+E E E+ Q +L +
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 208 QQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQ--QEGQLELSEQQEGQLKH 265
Q+E ++ EQ+E E+ Q E Q+QE +++ E+ +E ++ L +Q+E
Sbjct: 494 QEE---KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEE----K 546
Query: 266 LEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLE------QQ 319
++ QE +L+ EE++G+L + G ++ P L +LK E QQ
Sbjct: 547 MQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606
Query: 320 EGQPKHLEQQEGQLEQL 336
+ HL+Q +QL
Sbjct: 607 DHYRGHLQQYVAAYQQL 623
Score = 55.8 bits (133), Expect = 1e-07
Identities = 72/322 (22%), Positives = 156/322 (48%), Gaps = 39/322 (12%)
Query: 295 HLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEG-QLEQLEEQEGQLKHLEQQEGQL 353
++++ K+ + P ++ + + +E + K+ E QE +L + E+ E QL +++ + +L
Sbjct: 191 YIEKLTKERDAPSLELYR-NTITDEELKEKNAELQEKLRLVESEKSEIQL-NVKDLKRKL 248
Query: 354 EHLEHQEGQLGLPEQQV-LQLKQLEKQ-QGQPKHLEE--EEGQLKHLVQQEGQLKHLVQQ 409
E QL LP+QQ+ ++ +L K+ Q L+ EE +L +L+ Q+ + K Q+
Sbjct: 249 ER-----AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQE 303
Query: 410 EGQLEQQERQVEH----LEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQP--KNL 463
E EQ+E+ E EQ+ + E+ Q + + +Q+ ++ E+++ + K
Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363
Query: 464 EQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVG-------------------QPKHLE 504
EQEEK E+ Q + +++QE ++ E+++ Q + +
Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423
Query: 505 QQEKHLEHPEQQDGQLKHLEQ-QEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKG 563
+QE+ + E++ +L+ + Q QE +L+++E +K Q E+ ++Q + + +
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVE-EKMQEEEEKMQEQEEKIQRQEEKIQEQE 482
Query: 564 EVLLPVEHQQQKQEVQWPPKHK 585
E E +++E W + K
Sbjct: 483 EKTWRQEKLLKQEEKIWEQEEK 504
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 106 bits (265), Expect = 5e-23
Identities = 145/562 (25%), Positives = 249/562 (44%), Gaps = 87/562 (15%)
Query: 73 QECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ 132
QE +Q + QE WE+ + E +QQ EEK+LL+Q
Sbjct: 464 QEADQLWRRLQELLAHTSSWEEELAELRREKKQQQ-----------------EEKELLEQ 506
Query: 133 Q---LDQELVKRDEQLGMKKEQLLELPEQQEGHLK---HLEQQEGQLKHPEQQEGQLELP 186
+ L ++L + QL + + +L EQ++ ++ HL QQ G L+ G ELP
Sbjct: 507 EVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGP-ELP 565
Query: 187 ---EQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQL 243
E+ E + + + PE+++ L QE QL+ + QEG E + ++
Sbjct: 566 VAGEKNEALVPVNSSLQEAWGKPEEEQRGL-----QEAQLDDTKVQEGSQE-EELRQANR 619
Query: 244 ELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQM-GQLKYLEQQEGQLKHL-DQQE- 300
EL ++ + + ++ EG+L+ L+ L+ E + G L LE ++ ++HL DQ E
Sbjct: 620 ELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEA 679
Query: 301 ------KQPELPEQQMGQLKH-LEQQEGQPKHLEQQEGQLEQL-EEQEGQLKHLE---QQ 349
K E + QM + + L+ +EG+ + L ++ Q +QL E + +L+ LE QQ
Sbjct: 680 SLLAVRKAKEAMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQ 739
Query: 350 EGQL-EHLEHQEGQLG-----------LPEQQVLQLKQLEKQQGQPKHLEEEEGQLK--- 394
+ QL E L ++GQ G L Q L QLE QG+ + L+ + L+
Sbjct: 740 QTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKM 799
Query: 395 --HLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQ--------VGQLKHLEEQEGQLK--- 441
L Q+ L E L + + V+ L++Q V +L E+EG L+
Sbjct: 800 RAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEER 859
Query: 442 --HLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQ 499
+Q++ +L ++++ Q K EE QLE E QE Q+ A+L + +
Sbjct: 860 ADEAQQREEELRALQEELSQAK-CSSEEAQLEHAELQE-QLHRANTDTAELGIQVCALTV 917
Query: 500 PKHLEQQEKHLEHPEQQDGQLKHLEQQEG---QLKDLEQQKGQLEQPVFA--PAPGQVQD 554
K ++ E QD + ++EG Q+ L+Q+K L++ + A A G +
Sbjct: 918 EKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPG 977
Query: 555 IQPAL---PTKGEVLLPVEHQQ 573
+Q L + + L HQ+
Sbjct: 978 LQAQLAQAEQRAQSLQEAAHQE 999
Score = 82.8 bits (203), Expect = 8e-16
Identities = 136/528 (25%), Positives = 233/528 (44%), Gaps = 69/528 (13%)
Query: 86 ELQQQHWEQHEEYQKA----ENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKR 141
ELQ+Q WE + Q + Q L+ ++++ + L + +L Q L QEL
Sbjct: 297 ELQKQ-WEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESML-QPLAQELEAT 354
Query: 142 DEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEG 201
+ L K + L P G L +Q+ + ++ + QE Q EL E+ +
Sbjct: 355 RDSLDKKNQHLASFP----GWLAMAQQKADTASDTKGRQEPIPSDAAQEMQ-ELGEKLQA 409
Query: 202 QLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLE--LSEQQEGQLELSE-- 257
L ++ E+ QQ QLE Q +L+L + LE + E Q ELS
Sbjct: 410 ---LERERTKVEEVNRQQSAQLE---QLVKELQLKEDARASLERLVKEMAPLQEELSGKG 463
Query: 258 QQEGQL-KHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQE-----KQPELPEQQMG 311
Q+ QL + L+ EE++ +L+ ++Q+ + K L +QE +Q + E Q+
Sbjct: 464 QEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLA 523
Query: 312 QL-KHLEQQEGQPK-------HLEQQEGQLEQLEEQEGQLKHL--EQQEGQLEHLEHQEG 361
Q+ +H+ E Q K HL QQ G LE+L G + E+ E + +
Sbjct: 524 QVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPVNSSLQE 583
Query: 362 QLGLPE--QQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQ----EGQLEQ 415
G PE Q+ LQ QL+ + Q EEE Q +++E L+++V + EG+L+
Sbjct: 584 AWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQANRELEKE--LQNVVGRNQLLEGKLQA 641
Query: 416 QERQVEHLEQQV----GQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLE 471
+ + L+Q+ G L LE ++ ++HL Q + ++ + + EK+
Sbjct: 642 LQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAEKEAI 701
Query: 472 LPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLK 531
L + +EG+ + L ++ Q QQ+ + +H E + LE QQ QL ++
Sbjct: 702 L-QSKEGECQQLREEVEQC----QQLAEARHREL--RALESQCQQQTQL---------IE 745
Query: 532 DLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQ 579
L +KGQ Q V P + +++ L + L V HQ + Q +Q
Sbjct: 746 VLTAEKGQ--QGVGPPTDNEARELAAQL-ALSQAQLEV-HQGEVQRLQ 789
Score = 73.6 bits (179), Expect = 5e-13
Identities = 138/550 (25%), Positives = 229/550 (41%), Gaps = 92/550 (16%)
Query: 42 PPCQKVPV-----ELPVEVPSKQEE---KHMTAVKGLPEQECEQQ--QKEPQEQELQQQH 91
PP ++PV E V V S +E K +GL E + + Q+ QE+EL+Q +
Sbjct: 559 PPGPELPVAGEKNEALVPVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQAN 618
Query: 92 WEQHEEYQKAENPEQQL--KQEKTQRDQQLNKQLEE--EKKLLDQQLDQELVKRDEQLGM 147
E +E Q Q L K + Q D Q +Q E + L + +Q ++ LG
Sbjct: 619 RELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRH---LGD 675
Query: 148 KKE-QLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQL-ELPEQQEGQLEL 205
+ E LL + + +E + ++E L+ E + QL +Q QL E ++ LE
Sbjct: 676 QMEASLLAVRKAKEAMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALES 735
Query: 206 PEQQEGQL-ELPEQQEGQLEL--PEQQEG-----QLELPQQQ--EGQLELSEQQEGQLEL 255
QQ+ QL E+ ++GQ + P E QL L Q Q Q E+ Q ++L
Sbjct: 736 QCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDL 795
Query: 256 SEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKH 315
+ L + + QL + E + + K L QQ LK ++ + + E +
Sbjct: 796 QAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQ---LKEQNEALNRAHVQELLQCSERE 852
Query: 316 LEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE---------GQLGLP 366
QE + +Q+E +L L+E+ Q K +E QLEH E QE +LG+
Sbjct: 853 GALQEERADEAQQREEELRALQEELSQAK-CSSEEAQLEHAELQEQLHRANTDTAELGIQ 911
Query: 367 E----------QQVLQLKQLEKQQGQPKHLEEEEG---QLKHLVQQEGQLKHLVQQ---- 409
++ L E Q + E EG Q+ L Q++ L+ ++
Sbjct: 912 VCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAA 971
Query: 410 -------EGQLEQQERQVEHLE----QQVGQLK-----HLEEQEGQLKH----------- 442
+ QL Q E++ + L+ Q++ LK + + + +LK+
Sbjct: 972 AGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQ 1031
Query: 443 LEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHL-EKQEAQLELPEQQVGQPK 501
LE+Q QL+ E+ V + K Q ++ E+ HL E Q A L ++ +
Sbjct: 1032 LEEQGRQLQAAEEAVEKLK-----ATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALRE 1086
Query: 502 HLEQQEKHLE 511
LE+ +K LE
Sbjct: 1087 DLERTQKELE 1096
Score = 72.4 bits (176), Expect = 1e-12
Identities = 106/466 (22%), Positives = 211/466 (45%), Gaps = 68/466 (14%)
Query: 130 LDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQ 189
L+ L+ E ++ +++ ++ +QL +Q ++ L+++ +L+ Q+G+ E++
Sbjct: 220 LNSPLNNEALEGFDEMRLELDQLEVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERE 279
Query: 190 EGQL-------------ELPEQ-------QEGQLELPEQQEG-QLELPEQQEGQLELPEQ 228
G+ EL +Q Q EL +G +L E++E +
Sbjct: 280 RGRTAAEDNVRLTCLVAELQKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRR 339
Query: 229 QEGQLE-LPQQQEGQLELSEQQE-------GQLELSEQQEGQLKHLEHQEGQLEVPEEQM 280
E L+ L Q+ E + +++ G L +++Q+ + + Q +P +
Sbjct: 340 LESMLQPLAQELEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGR--QEPIPSDAA 397
Query: 281 GQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQL----KHLEQQEGQPKHLEQQEGQLEQL 336
+++ L ++ L+ ++ K E+ QQ QL K L+ +E LE+ ++ L
Sbjct: 398 QEMQELGEKLQALER--ERTKVEEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPL 455
Query: 337 EEQEGQLKHLEQQEGQL-EHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKH 395
+E+ L Q+ QL L+ E+++ +L++ +KQQ + K L E+E ++
Sbjct: 456 QEE---LSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQE--VRS 510
Query: 396 LVQQ----EGQLKHLVQQEGQLEQQERQV----EHLEQQVGQLKHLEEQEGQLKHLEQQQ 447
L +Q E QL + Q LE+Q++Q+ +HL QQVG L+ L G + ++
Sbjct: 511 LTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEK 570
Query: 448 GQLEVP-----EQQVGQPKNLEQ--EEKQLELPEQQEG-QVKHLEKQEAQLELPEQQV-- 497
+ VP ++ G+P+ ++ +E QL+ + QEG Q + L + +LE Q V
Sbjct: 571 NEALVPVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQANRELEKELQNVVG 630
Query: 498 ------GQPKHLEQQEKHLEHPEQQ-DGQLKHLEQQEGQLKDLEQQ 536
G+ + L+ + L+ E G L LE ++ ++ L Q
Sbjct: 631 RNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQ 676
Score = 64.3 bits (155), Expect = 3e-10
Identities = 101/462 (21%), Positives = 194/462 (41%), Gaps = 29/462 (6%)
Query: 17 QELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECE 76
Q+L + + + Q +Q T L + V P+ E + + A L + + E
Sbjct: 720 QQLAEARHRELRALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQAQLE 779
Query: 77 QQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNK------QLEEEKKLL 130
Q E Q LQ Q + + + A + + +++ + + + L + QL+E+ + L
Sbjct: 780 VHQGEVQR--LQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEAL 837
Query: 131 DQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQE 190
++ QEL++ E+ G +E+ + +Q+E L+ L+++ Q K +E QLE E QE
Sbjct: 838 NRAHVQELLQCSEREGALQEERADEAQQREEELRALQEELSQAK-CSSEEAQLEHAELQE 896
Query: 191 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQL--ELPEQQEGQLELPQQQEGQLELSEQ 248
+L EL Q E+ E L + E Q+ + +++EG L Q
Sbjct: 897 ---QLHRANTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREG---LERQ 950
Query: 249 QEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQ 308
G + E + +LK + G L + Q+ Q + Q + H + + +L +
Sbjct: 951 VAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAE 1010
Query: 309 QMGQLKHLEQQEGQPK----HLEQQEGQLEQLEEQEGQLKHLEQQEGQ-----LEHL-EH 358
M L+ + K LE+Q QL+ EE +LK + G+ HL E
Sbjct: 1011 IMDYQSRLKNAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAEC 1070
Query: 359 QEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQE--GQLEQQ 416
Q L ++ + LE+ Q + + + + + + QE + Q+ L+
Sbjct: 1071 QAAMLRKDKEGAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDL 1130
Query: 417 ERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVG 458
R ++LE+++ +L ++ Q + Q +L E+ +G
Sbjct: 1131 NRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEERWLG 1172
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 104 bits (260), Expect = 2e-22
Identities = 120/452 (26%), Positives = 226/452 (50%), Gaps = 68/452 (15%)
Query: 70 LPEQECEQQQK----EPQEQELQQQHWEQHEEYQKAEN--PEQQLKQEKTQRDQQLNK-- 121
L E+ E Q+K E ++ E+Q + + ++A+ P+QQL+ E + ++L
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
Query: 122 -----QLEEEK--KLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLK 174
Q+EE + LL+QQ ++++ +++E++ ++E++ E QE LK EQ+E +
Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE----QE--LKIREQEEKMWR 329
Query: 175 HPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLE 234
E+ Q E +QE ++ E++ + EQ+E ++ EQ+E E+ Q E
Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEEK-----IREQEE---KIREQEEKMWRQEEKIREQDE 381
Query: 235 LPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLK 294
Q+QE ++ E++ + EQ+E + + + QE ++ +E K EQ+E +
Sbjct: 382 KIQEQEEEMWRQEEK-----IREQEEKRQEKMWRQEKKMREQDE-----KIREQEEEMWR 431
Query: 295 HLDQQEKQPELPEQQMGQLKHL-EQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQL 353
Q+EK EL E Q + L E +E + E+ + Q E+++ QE +++ E++ +
Sbjct: 432 ---QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ 488
Query: 354 EHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQL 413
E L QE ++ EQ+ +Q EK Q + ++E+E +++ +QE +++ +QE +L
Sbjct: 489 EKLLKQEEKIW--EQEEKMWRQEEKMWEQEEKMQEQEEKMQ---RQEEKMR---EQEVRL 540
Query: 414 EQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELP 473
QQE + ++EQE +L+ LE++ G+L + +G +E LP
Sbjct: 541 WQQEEK-------------MQEQEVRLQELEERLGKLGQKAELLG---GAGRESGSQRLP 584
Query: 474 EQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQ 505
L+ QEAQ L +QQ HL+Q
Sbjct: 585 TLTPILQVELKSQEAQ-SLQQQQDHYRGHLQQ 615
Score = 100 bits (249), Expect = 4e-21
Identities = 117/506 (23%), Positives = 239/506 (47%), Gaps = 69/506 (13%)
Query: 92 WEQHEEYQKAENPEQQLKQEKTQRDQQLN-----KQLEEEKKLLDQQLDQELVKRDEQLG 146
W + E + PE L +E D + ++L +E+ L +L + + DE+L
Sbjct: 159 WLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTIT-DEELK 217
Query: 147 MKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELP 206
K +L E E ++ LK + + QL LP+QQ L++ + G+
Sbjct: 218 EKNAELQEKLRLVESEKSEIQLNVKDLKR-KLERAQLLLPQQQ---LQVEADRLGK---- 269
Query: 207 EQQEGQLELPEQ-QEGQL-ELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQE---G 261
E Q +L Q +E +L L QQ+ + Q+++ Q + + E +L++ EQ+E
Sbjct: 270 ELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR 329
Query: 262 QLKHLEHQEGQLEVPEEQM-GQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQE 320
Q + + QE ++ E++M Q + + +QE +++ +Q+EK E+ Q + +++QE
Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR--EQEEKMWRQEEKIREQDEKIQEQE 387
Query: 321 GQPKHLEQQEGQLEQLEE--QEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEK 378
+ + +QE ++ + EE QE + ++ Q E + QE ++ E+++ +L+++ +
Sbjct: 388 ---EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 379 QQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEG 438
Q EE+ +++ +Q+E + + +QE ++++QE +++ E++ + + L +QE
Sbjct: 445 DQ------EEKLREVEEKMQEEEE--KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496
Query: 439 QLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVG 498
++ E++ + E K EQEEK E E+ + Q + + +QE +L
Sbjct: 497 KIWEQEEKMWRQE--------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRL-------- 540
Query: 499 QPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPA 558
+Q+EK +++QE +L++LE++ G+L Q +
Sbjct: 541 ----WQQEEK--------------MQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR 582
Query: 559 LPTKGEVLLPVEHQQQKQEVQWPPKH 584
LPT +L Q+ Q +Q H
Sbjct: 583 LPTLTPILQVELKSQEAQSLQQQQDH 608
Score = 94.0 bits (232), Expect = 3e-19
Identities = 93/353 (26%), Positives = 187/353 (52%), Gaps = 30/353 (8%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQ 117
+QEEK + + EQE + ++E + +E +++ W Q E K E+++++++ + +
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE---KMHEQEEKIREQEDKMWR 350
Query: 118 QLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPE 177
Q K E+E+K+ +Q ++++ +++E++ +EQ ++ EQ+E + +QE +++ E
Sbjct: 351 QEEKIREQEEKIREQ--EEKMWRQEEKI---REQDEKIQEQEE----EMWRQEEKIR--E 399
Query: 178 QQEGQLELPEQQEGQLELPEQ--QEGQLELPEQQEGQLELPEQQEGQLE-LPEQQEGQLE 234
Q+E + E +QE ++ ++ +E + E+ Q+E EL E + Q E L E +E E
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 235 LPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQM--GQLKYLEQQEGQ 292
++ + Q E ++QE +++ E++ + + L QE ++ EE+M + K EQ+E
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE-- 517
Query: 293 LKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQ 352
K +Q+EK E+ Q L QQE + +++QE +L++LEE+ G+ L Q+
Sbjct: 518 -KMQEQEEKMQRQEEKMREQEVRLWQQE---EKMQEQEVRLQELEERLGK---LGQKAEL 570
Query: 353 LEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEE--EGQLKHLVQQEGQL 403
L + G LP + +L+ Q+ Q +++ G L+ V QL
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Score = 92.0 bits (227), Expect = 1e-18
Identities = 107/400 (26%), Positives = 205/400 (51%), Gaps = 51/400 (12%)
Query: 50 ELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENP--EQQ 107
+L VE +E + K L Q E + Q+ +++ W Q E+ Q+ E EQ+
Sbjct: 259 QLQVEADRLGKELQSVSAK-LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE 317
Query: 108 LK----QEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHL 163
LK +EK R ++ K E+E+K+ +Q+ ++ +++E++ ++E++ E E+
Sbjct: 318 LKIREQEEKMWRQEE--KMHEQEEKIREQE--DKMWRQEEKIREQEEKIREQEEKMWRQE 373
Query: 164 KHLEQQEGQLKHPEQQEGQLE--LPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEG 221
+ + +Q+ +++ E++ + E + EQ+E + E +QE ++ EQ E ++ EQ+E
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR--EQDE---KIREQEE- 427
Query: 222 QLELPEQQEGQLELPQQQEGQLE-LSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQM 280
E+ Q+E EL + + Q E L E +E E E+ + Q + ++ QE +++ EE+
Sbjct: 428 --EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT 485
Query: 281 G-QLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQ 339
Q K L+Q+E K +Q+EK E+ Q + +++QE + +++QE E++ EQ
Sbjct: 486 WRQEKLLKQEE---KIWEQEEKMWRQEEKMWEQEEKMQEQE---EKMQRQE---EKMREQ 536
Query: 340 EGQL----KHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKH 395
E +L + +++QE +L+ LE + G+LG Q+ L ++ G + L
Sbjct: 537 EVRLWQQEEKMQEQEVRLQELEERLGKLG---QKAELLGGAGRESG-----SQRLPTLTP 588
Query: 396 LVQQEGQLKHLVQQEGQ--LEQQERQVEHLEQQVGQLKHL 433
++Q E L QE Q +QQ+ HL+Q V + L
Sbjct: 589 ILQVE-----LKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Score = 80.5 bits (197), Expect = 4e-15
Identities = 78/317 (24%), Positives = 158/317 (49%), Gaps = 34/317 (10%)
Query: 45 QKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQK---- 100
Q++ + E +QEEK + + EQE + ++E + +E +++ EQ E+ +
Sbjct: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
Query: 101 --------AENPEQQLKQEKTQRDQQLNKQ---LEEEKKLLDQQLDQELVKRDEQLGMKK 149
E E+ +QE+ R+Q+ +Q +EKK+ +Q D+++ +++E++ ++
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ--DEKIREQEEEMWRQE 433
Query: 150 EQLLELPEQQEGHLKHLEQQEGQLKHPEQ--QEGQLELPEQQEGQLELPEQQEGQLELPE 207
E++ EL E + + L + E +++ E+ QE + ++ Q+E E E+ Q +L +
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 208 QQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQ--QEGQLELSEQQEGQLKH 265
Q+E ++ EQ+E E+ Q E Q+QE +++ E+ +E ++ L +Q+E
Sbjct: 494 QEE---KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEE----K 546
Query: 266 LEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLE------QQ 319
++ QE +L+ EE++G+L + G ++ P L +LK E QQ
Sbjct: 547 MQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606
Query: 320 EGQPKHLEQQEGQLEQL 336
+ HL+Q +QL
Sbjct: 607 DHYRGHLQQYVAAYQQL 623
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 104 bits (259), Expect = 3e-22
Identities = 156/675 (23%), Positives = 303/675 (44%), Gaps = 118/675 (17%)
Query: 20 LKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQE------------EKHMTAV 67
LK V+ QEQ+++ C+ V LP+ V +++ EK
Sbjct: 1465 LKKRNQEVDLQQEQIQELEK----CRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQ 1520
Query: 68 KGLPEQECEQQQKEPQE--------QELQQQ-------HWEQHEEYQKAENPEQQLKQEK 112
+ + E + + +K+ Q Q+L++Q E E + K E ++ +K+ +
Sbjct: 1521 RNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELE 1580
Query: 113 TQRDQQ------LNKQLEEEKKLLDQQLDQ-------------ELVKRDEQLGMKKEQLL 153
QR+ Q L LEE + L Q Q EL +RD+++ ++EQ+
Sbjct: 1581 GQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIE 1640
Query: 154 ELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL 213
EL Q+E + LE+++ +L Q+E L +Q+ Q ++ E+ Q++L ++ G+
Sbjct: 1641 ELQRQKEHLTQDLERRDQELM--LQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGR- 1697
Query: 214 ELPEQQEGQLELPEQ-------QEGQLE----LPQQQEGQLELSEQQEGQL-ELSEQQEG 261
EL Q++ E E+ Q G LE + + +E ++E ++ +L EL +Q E
Sbjct: 1698 ELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQ 1757
Query: 262 QLKHLEHQEGQLEVPEEQMGQ-LKYLEQQ------EGQLK------HLDQQEKQPELPEQ 308
QL+ L + G+ + Q Q + L+QQ +G+LK LD+ ++ +Q
Sbjct: 1758 QLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQ 1817
Query: 309 QMGQLKHLEQQ-EGQPKHLEQQ----EGQLEQ----LEEQEGQLKHLEQQEGQLEHLEHQ 359
++ L+ +QQ +GQ + ++++ +G LEQ L+E+ G+L+ ++Q +LE
Sbjct: 1818 ELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAV 1877
Query: 360 EGQLGLPEQQVLQLKQLEKQQGQPKHLEEE----EGQLKHLVQQEGQLKHLVQQEGQLEQ 415
EG+ ++VL + E ++ + L + E +H V+ +Q + L++
Sbjct: 1878 EGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKE 1937
Query: 416 QERQVEHLEQQVGQLKHLEE---------QEGQLKHLEQQQGQLEVPEQQVGQPKNLEQE 466
+++++E L + +H EE QE K QG+ + +Q ++LE
Sbjct: 1938 RDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEAS 1997
Query: 467 EKQL------------ELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPE 514
L +L E Q ++ Q+ + + QQ+ Q L Q+++ L H +
Sbjct: 1998 TATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQA--LAQRDEELRHQQ 2055
Query: 515 QQDGQL-KHLEQ--QEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEH 571
+++ L K L Q QE +++ + + E+ V+++Q L K + +L +
Sbjct: 2056 EREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRE 2115
Query: 572 QQQKQEVQ-WPPKHK 585
QQ+ ++ P HK
Sbjct: 2116 TQQRNNLEALPHSHK 2130
Score = 100 bits (249), Expect = 4e-21
Identities = 139/515 (26%), Positives = 243/515 (47%), Gaps = 72/515 (13%)
Query: 70 LPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKL 129
L + E E+ Q + Q+LQ+Q + EE K E + L+ E +L E
Sbjct: 1273 LTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESEL--------MELHETMAS 1324
Query: 130 LDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLE----- 184
L +L + ++R E G ++E L E ++HL+ + + G LE
Sbjct: 1325 LQSRLRRAELQRMEAQG-ERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRT 1383
Query: 185 -------LPEQQEGQLELPE--QQEGQLELPEQQEGQLELPEQQEGQLELPEQQE---GQ 232
E+ E + E + Q++G+L++ + + Q L + E E+ E GQ
Sbjct: 1384 ARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQ 1443
Query: 233 L-ELPQQQEGQ--------LELSEQ------QEGQLELSEQQEGQLKHL----EHQEGQL 273
+ EL +Q+E Q L+L ++ Q+ Q++ E+ L+HL + +E +L
Sbjct: 1444 IQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKL 1503
Query: 274 EVPEEQMGQL-KYLEQQEGQLKH-LDQQEKQPELPEQQMGQLKHLEQQEGQPKHLE-QQE 330
V EQ+ +L K E Q L+H L + EK+ ++ E Q GQ++ L++Q + L + E
Sbjct: 1504 TVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELE 1563
Query: 331 GQLEQLEEQEGQLKHLE-QQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEE 389
++E Q+ +K LE Q+E Q L H L L E+ ++L+ Q Q LE
Sbjct: 1564 ENHHKMECQQKLIKELEGQRETQRVALTHL--TLDLEERS----QELQAQSSQIHDLESH 1617
Query: 390 EGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQ 449
L +Q+ Q + Q Q+E+ +RQ EHL Q + E+ Q L++++ Q
Sbjct: 1618 STVLARELQERDQ--EVKSQREQIEELQRQKEHLTQDL-------ERRDQELMLQKERIQ 1668
Query: 450 LEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKH 509
+ + +Q+ Q K LE++ +Q++L ++ G+ ++Q Q E E+ G K Q
Sbjct: 1669 V-LEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQ-ERAEEGKGPSK---AQRGS 1723
Query: 510 LEHPE--QQDGQLKHLEQQEGQLKDLEQQKGQLEQ 542
LEH + +D + K +E Q+ + +L++ K QLEQ
Sbjct: 1724 LEHMKLILRDKE-KEVECQQEHIHELQELKDQLEQ 1757
Score = 87.4 bits (215), Expect = 3e-17
Identities = 114/476 (23%), Positives = 216/476 (45%), Gaps = 36/476 (7%)
Query: 72 EQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLD 131
E + + + + +++E+Q++ E + + A +QL QE ++++ L + ++E++ L+
Sbjct: 677 ELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVR 736
Query: 132 QQLDQEL----VKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPE 187
++ E+ V+RD Q +L EQ +G E E L +QQ +E+ +
Sbjct: 737 EKAALEVRLQAVERDRQ---------DLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTK 787
Query: 188 QQEGQLELPEQQEGQLELPEQQEGQ-LELPEQQEGQLELPEQQEGQLELPQ-QQEGQLEL 245
GQLE+ Q Q + Q E + L+L E E+ +L Q +QEG+ L
Sbjct: 788 ---GQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTAL 844
Query: 246 SEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLK-HLDQQEKQPE 304
+Q+ E++ QL+ +E +E L+ LE+++ +L+ L +Q+ + E
Sbjct: 845 EQQKAAH----EKEVNQLREKWEKERSWH-QQELAKALESLEREKMELEMRLKEQQTEME 899
Query: 305 LPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLG 364
+ Q + + + LE ++ ++ LE K L QLE L
Sbjct: 900 AIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQK 959
Query: 365 LPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLE 424
L EQ+ + Q + Q+ Q + E L + + L+Q + L+ +QVE L+
Sbjct: 960 LKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQ---KQVEDLK 1016
Query: 425 QQV---GQLKHLEEQEGQLKHLEQQQG---QLEVPEQQVGQPKNLEQEEKQLELPEQQEG 478
Q+ + L EQE Q K E Q+ Q E+ ++ +L ++E++L L Q+
Sbjct: 1017 SQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRL-LVLQEAD 1075
Query: 479 QVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLE 534
++ E + ++ E Q G+ K L Q + L E ++ + L Q+ L++LE
Sbjct: 1076 SIRQQELSALRQDMQEAQ-GEQKELSAQMELLRQ-EVKEKEADFLAQEAQLLEELE 1129
Score = 82.0 bits (201), Expect = 1e-15
Identities = 132/517 (25%), Positives = 237/517 (45%), Gaps = 70/517 (13%)
Query: 56 PSKQEE---KHMTAVKGLPEQECEQQQ---------KEPQEQELQQQHWEQHE------- 96
PSK + +HM + E+E E QQ K+ EQ+LQ H + E
Sbjct: 1716 PSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQ 1775
Query: 97 EYQKAENPEQQLKQEKTQ---RDQQLNKQLEEEKKLLDQQLDQELV---KRDEQLGMKKE 150
Q+ +QQL++ + Q ++Q L QL+E ++ L Q+ DQEL + +Q ++E
Sbjct: 1776 REQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR-DQELEALQQEQQQAQGQEE 1834
Query: 151 QLLELPEQQEGHLKH----LEQQEGQLKHPEQQEGQLELPEQQEGQ-LELPEQQEGQL-- 203
++ E + +G L+ L+++ G+L+ ++Q +LE EG+ ++ E+ G L
Sbjct: 1835 RVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRA 1894
Query: 204 ELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELS---EQQEGQLELSEQQE 260
E EQ++ L L +Q Q QE ++E Q+ L+ ++++ +LE +
Sbjct: 1895 ESREQEKALLALQQQCAEQA-----QEHEVETRALQDSWLQAQAVLKERDQELEALRAES 1949
Query: 261 GQLKHLEHQ-EGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLK-HLEQ 318
+H E + E +E +G+ Q G+ +HL +Q + E L+ L+
Sbjct: 1950 QSSRHQEEAARARAEALQEALGKAHAALQ--GKEQHLLEQAELSRSLEASTATLQASLDA 2007
Query: 319 QEGQPKHLEQ----QEGQLE----QLEEQEGQLKH-LEQQEGQLEHLEHQEGQLGLPEQQ 369
+ + LE+ QEG+++ + +E QL+ L Q++ +L H + +E L Q
Sbjct: 2008 CQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQ 2067
Query: 370 VLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQL----EQQERQVEHLEQ 425
+Q ++++Q + EEEE + H +E QL L Q+E ++ E Q+R
Sbjct: 2068 RVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLT-LAQKEQEILELRETQQRNNLEALP 2126
Query: 426 QVGQLKHLEEQEGQLKHLEQQ-QGQLEVPEQQVGQ--PKNLEQEEKQLELP---EQQEGQ 479
+ +EEQ +L LE + Q +LE + + Q + +E EK +L Q +
Sbjct: 2127 HSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKAS 2186
Query: 480 VKHLEK-----QEAQLELPEQQVGQPKHLEQQEKHLE 511
V L++ Q + LE +Q LE + LE
Sbjct: 2187 VSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALE 2223
Score = 79.0 bits (193), Expect = 1e-14
Identities = 119/506 (23%), Positives = 220/506 (43%), Gaps = 74/506 (14%)
Query: 57 SKQEEKHMTAVKGLPEQEC-EQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQR 115
S+++EK + A+ +Q+C EQ Q+ E Q W Q + K E+ + E +
Sbjct: 1896 SREQEKALLAL----QQQCAEQAQEHEVETRALQDSWLQAQAVLK----ERDQELEALRA 1947
Query: 116 DQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQ---------------- 159
+ Q ++ EE + + L + L K L K++ LLE E
Sbjct: 1948 ESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDA 2007
Query: 160 -EGHLKHLEQ----QEGQLKHPE--QQEGQLELPE---QQEGQLELPEQQEGQLELPEQQ 209
+ H + LE+ QEG+++ + QE +L + Q++ +L +++E LE Q
Sbjct: 2008 CQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQ 2067
Query: 210 EGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSE-QQEGQLKHLEH 268
Q + ++++ + E++E + +E QL L+++++ LEL E QQ L+ L H
Sbjct: 2068 RVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPH 2127
Query: 269 QEGQLEVPEEQMGQLKYLEQQ-EGQLKHLDQQEKQPELPEQQMGQLKH-----LEQQEGQ 322
+ EEQ +L LE + + +L+ L +Q E E + + L Q +
Sbjct: 2128 SH-KTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKAS 2186
Query: 323 PKHLEQ-----QEGQLEQLEEQEGQLKHLEQQEGQLEHLE-HQEG-----QLGLPEQQVL 371
L++ Q LE+ EQ+ LE LE H G +LG +Q +
Sbjct: 2187 VSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGV 2246
Query: 372 QLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLK 431
QL ++ + +P +G K +Q +L+HL Q +LE +++ +
Sbjct: 2247 QLGEVSGVEAEPS----PDGMEKQSWRQ--RLEHLQQAVARLEIDRSRLQ---------R 2291
Query: 432 HLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLE 491
H + L+ +E+++ +L+ + Q +LE + P QQ+G+ + + E
Sbjct: 2292 HNVQLRSTLEQVERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKNSDAKCVAE 2351
Query: 492 LPEQQVGQPKHLEQQEKHLEHPEQQD 517
L ++ V L Q + LE ++QD
Sbjct: 2352 LQKEVV-----LLQAQLTLERKQKQD 2372
Score = 75.1 bits (183), Expect = 2e-13
Identities = 136/562 (24%), Positives = 230/562 (40%), Gaps = 90/562 (16%)
Query: 76 EQQQKEPQEQ-ELQQQHWE-QHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLD-- 131
+QQ +E +EQ EL++Q + Q +E Q+A Q + Q QQ Q E K+ D
Sbjct: 1784 QQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADAL 1843
Query: 132 ----QQLDQELVKRDEQLGMKKEQLLELPEQQ--EGH-LKHLEQQEGQLKHP--EQQEGQ 182
+Q L +R +L KEQ L E+ EG ++ LE+ G L+ EQ++
Sbjct: 1844 QGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKAL 1903
Query: 183 LELPEQ-----QEGQLELPEQQEGQLE----LPEQQEGQLELPEQQEGQLELPEQQEGQL 233
L L +Q QE ++E Q+ L+ L E+ + L + + E +
Sbjct: 1904 LALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARA 1963
Query: 234 ELPQQQEG---------------QLELSEQQEGQ-------LELSEQQEGQLKH-LEHQE 270
E Q+ G Q ELS E L+ + QL+ L QE
Sbjct: 1964 EALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQE 2023
Query: 271 GQLEVPE----EQMGQLKY-LEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQE--GQP 323
G+++ + E + QL+ L Q++ +L+H ++E+ E Q Q +++++ GQ
Sbjct: 2024 GEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQE 2083
Query: 324 KHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLP--------EQQVLQLKQ 375
+ E+ G + + E + L EQ+ +L + + LP E+Q L+L
Sbjct: 2084 REEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDS 2143
Query: 376 LEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEG-QLEQQERQVEHLEQ-----QVGQ 429
LE + + LE + L+ +E + + Q L Q + V L++ Q
Sbjct: 2144 LEPRL--QRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASV 2201
Query: 430 LKHLEEQEGQLKHLEQQQGQLEVP-----------------EQ--QVGQPKNLEQEEKQL 470
L+ EQ+ LE + LE EQ Q+G+ +E E
Sbjct: 2202 LERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPD 2261
Query: 471 ELPEQQEGQ-VKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQ 529
+ +Q Q ++HL++ A+LE+ ++ +H Q LE E++ +LK + Q
Sbjct: 2262 GMEKQSWRQRLEHLQQAVARLEIDRSRL--QRHNVQLRSTLEQVERERRKLKREAMRAAQ 2319
Query: 530 LKDLEQQKGQLEQPVFAPAPGQ 551
LE K P GQ
Sbjct: 2320 AGSLEISKATASSPTQQDGRGQ 2341
Score = 73.9 bits (180), Expect = 4e-13
Identities = 129/492 (26%), Positives = 215/492 (43%), Gaps = 52/492 (10%)
Query: 99 QKAENPEQQLK--QEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKE---QLL 153
Q ++ QQL QE QQ + Q EEE K L Q+L + +RD G + ++
Sbjct: 400 QAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVD 459
Query: 154 ELPEQQEGHLKHLEQQEGQLKHPEQQEGQL-----ELPEQQEGQLELPEQQEGQLELPEQ 208
L +++E K E+ QL+ EQ+ +L EL Q + E+Q+ +L L +
Sbjct: 460 SLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVR 519
Query: 209 QEGQLEL------PEQQEGQLEL--------PEQQEGQLELPQQQEGQLELSEQQEGQLE 254
+ +L+ +Q E EL EG+L +Q E L+ ++ E
Sbjct: 520 ERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAE 579
Query: 255 LSEQQ---EGQLKHLEHQEGQLEVPEEQMGQLKY-LEQQEGQLKHLDQQE-KQPELPEQQ 309
LS + + ++ L +L E + K L QQ QL+ +Q + E EQ
Sbjct: 580 LSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQA 639
Query: 310 MGQLK-HLEQQEGQPKHLEQQ----EGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLG 364
L+ L + E + + L ++ E QL++ EE +L+ + ++ Q E E Q+
Sbjct: 640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQ-ADLRDIQEEKEEIQKKLSE 698
Query: 365 LPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLE 424
QQ QLE+ + K +EE + + ++E ++ E +L+ ER + L
Sbjct: 699 SRHQQEAATTQLEQLHQEAKR--QEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLA 756
Query: 425 QQVGQLKHLEEQ-EGQLKHLEQQ-------QGQLEVPEQQVGQPKNLEQ-EEKQLELPEQ 475
+Q+ L +E E L +QQ +GQLEV Q V Q K + Q E + L+L
Sbjct: 757 EQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELD 816
Query: 476 QEGQVKHLEKQEAQLELPEQQVGQPKHLEQQ----EKHLEHPEQQDGQLKHLEQQE--GQ 529
E E+ A +L + + LEQQ EK + ++ + + QQE
Sbjct: 817 TERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKA 876
Query: 530 LKDLEQQKGQLE 541
L+ LE++K +LE
Sbjct: 877 LESLEREKMELE 888
Score = 65.5 bits (158), Expect = 1e-10
Identities = 129/545 (23%), Positives = 222/545 (40%), Gaps = 60/545 (11%)
Query: 57 SKQEEKHMTAVKGLPEQECE-----QQQKEPQEQELQQQHWEQHEEYQKAENPEQQ---- 107
S+ E++ A + L + E E +QQK E+E+ Q E+++K + QQ
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLR----EKWEKERSWHQQELAK 875
Query: 108 ----LKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHL 163
L++EK + + +L +Q + E + + Q ++E + + L + LE +++ L
Sbjct: 876 ALESLEREKMELEMRLKEQ-QTEMEAIQAQREEERTQAESAL---CQMQLETEKERVSLL 931
Query: 164 KHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPE-QQEGQ 222
+ L Q + +L Q QLE Q +L EQ+ + + QE Q EL E ++ +
Sbjct: 932 ETLLQTQKELADASQ---QLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHR 988
Query: 223 LELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQ 282
+L QE L Q + + E + QL +++ +L E QE E E Q
Sbjct: 989 DDLAALQEESSSLLQDKMDLQKQVEDLKSQL-VAQDDSQRLVEQEVQEKLRETQEYNRIQ 1047
Query: 283 LKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQ 342
K LE+++ L L EK+ L Q + + QQE + QE Q EQ +E Q
Sbjct: 1048 -KELEREKASLT-LSLMEKEQRLLVLQ--EADSIRQQELSALRQDMQEAQGEQ-KELSAQ 1102
Query: 343 LKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQ 402
++ L Q E +E + Q+ L++LE H+ E++ + Q+
Sbjct: 1103 MELLRQ--------EVKEKEADFLAQEAQLLEELE-----ASHITEQQLRASLWAQE--- 1146
Query: 403 LKHLVQQEGQLEQQERQVEHL--EQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQP 460
Q + +L E Q+E L EQQ G + Q L + QQ V E +
Sbjct: 1147 -AKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASL-YSALQQALGSVCESRPELS 1204
Query: 461 KNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQL 520
+ L Q G ++ L + V H Q+ + + +D
Sbjct: 1205 GGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDL-WKTQQTRDVLR 1263
Query: 521 KHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQW 580
+++ E +L D E +K Q+ ++QD+Q L E E +Q E +
Sbjct: 1264 DQVQKLEERLTDTEAEKSQVHT--------ELQDLQRQLSQNQEEKSKWEGKQNSLESEL 1315
Query: 581 PPKHK 585
H+
Sbjct: 1316 MELHE 1320
Score = 50.1 bits (118), Expect = 6e-06
Identities = 114/540 (21%), Positives = 207/540 (38%), Gaps = 58/540 (10%)
Query: 28 NTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQEL 87
N+ + Q +Q T + KV L ++ EK + A G Q E + EP EL
Sbjct: 44 NSQEAQQRQATLVRKLQAKV---LQYRSWCQELEKRLEATGGPIPQRWENVE-EPNLDEL 99
Query: 88 QQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEE--EKKLLD-QQLDQELVKRDEQ 144
+ E+ + + QL+ + D +NK L E EK +D + EL++++ Q
Sbjct: 100 LVRLEEEQQRCESLAEVNTQLRLHMEKADV-VNKALREDVEKLTVDWSRARDELMRKESQ 158
Query: 145 LGMKKE-------------------------QLLELPEQQEGHLKHLEQQEGQLKHP--- 176
M++E LE+ + L L+ + +L
Sbjct: 159 WQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLT 218
Query: 177 ---EQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL 233
G G+++ E + L L + QE + E E+ + ++L Q G L
Sbjct: 219 CCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELIQLKSQ--GDL 276
Query: 234 ELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQL 293
E + Q+ ELS + +E E +K L LE ++ + + + Q
Sbjct: 277 EKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQE 336
Query: 294 KHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQL 353
+ L Q+ ++ + + + ++ Q G LE Q + Q+ K L L
Sbjct: 337 EKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDAD-KALTLVRSVL 395
Query: 354 EHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQ-EGQLKHLVQQ--- 409
++ L +Q + + Q Q EEE L+ +Q+ G+ L Q
Sbjct: 396 --TRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVD 453
Query: 410 -EGQLEQQERQVEHLEQQVGQLK-HLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEE 467
+G+++ ++ E L++ +L+ LE E + L + +L++ K +QEE
Sbjct: 454 LQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEE 513
Query: 468 KQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQE 527
L + E++ Q + + Q E + + + LE HLE G+L EQ E
Sbjct: 514 LHLAVRERERLQEMLMGLEAKQSESLSELITLREALE--SSHLE------GELLRQEQTE 565
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 98.2 bits (243), Expect = 2e-20
Identities = 124/535 (23%), Positives = 197/535 (36%), Gaps = 25/535 (4%)
Query: 42 PPCQKVPVELPVEVPSKQEEKH------MTAVKGLPEQECEQQQKEPQEQELQQQHWEQH 95
P +P + ++ EE+ M+ +GLP+ E +Q+ H
Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSH 91
Query: 96 EEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLEL 155
Q P+ + + E+KL + +K + KE+
Sbjct: 92 PPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEE--HK 149
Query: 156 PEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL 215
G L + + + + + Q E ++Q+ + + EG ++
Sbjct: 150 SSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKP 209
Query: 216 PEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEV 275
P QQ+ +P+QQ G P QQ+G + Q+ + ++ Q G K ++ G +
Sbjct: 210 PLQQQPPKPIPKQQ-GPGRDPLQQDGTPKSISSQQPE-KIKSQPPGTGKPIQ---GPTQT 264
Query: 276 PEEQMGQLKYL-EQQEGQLKHLD---QQEKQPELPEQQMGQLKHL---EQQEGQPKHLEQ 328
P+ +L + Q K D + +P LP ++ + QP H +
Sbjct: 265 PQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS 324
Query: 329 QEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEE 388
Q G + + G K L QQ G ++ G P Q + K +Q G K E
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384
Query: 389 EEGQLKHLVQQEGQLKHLVQQEGQLEQQERQV---EHLEQQVGQLKHLEEQEGQLKHLEQ 445
+ G K L Q G K QQ G + +QV + L QQ G L+ + G K Q
Sbjct: 385 QPGP-KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG-LQSPAKAPGPTKTPVQ 442
Query: 446 QQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQ 505
Q G ++P QQ G K Q+ + P Q G K +Q + P QQ G K Q
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 506 QEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALP 560
Q + P QQ G K QQ G K QQ G + P+P + Q P
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Score = 85.5 bits (210), Expect = 1e-16
Identities = 114/428 (26%), Positives = 159/428 (37%), Gaps = 63/428 (14%)
Query: 154 ELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEG-----QLELPEQ 208
E ++Q+ K + EG +K P QQ+ +P+QQ G P QQ+G + PE+
Sbjct: 188 ETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQ-GPGRDPLQQDGTPKSISSQQPEK 246
Query: 209 QEGQLE-LPEQQEGQLELPEQQEGQLEL------PQQQEGQLELSEQQEGQLE------L 255
+ Q + +G + P+ +L L PQ ++ + E + L +
Sbjct: 247 IKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPI 306
Query: 256 SEQQEG-----QLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQM 310
+ G Q H + Q G + P + G K L QQ G +K Q + P Q +
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366
Query: 311 GQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQV 370
G K QQ G K +Q G K L Q G + Q G P QQV
Sbjct: 367 GPAKPPAQQTGSEKPSSEQPGP-----------KALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 371 LQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQL 430
G PK L ++ G L+ + G K VQQ G + QQ G
Sbjct: 416 ----------GTPKPLAQQPG-LQSPAKAPGPTKTPVQQPGPGKIPA-------QQAGPG 457
Query: 431 KHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQL 490
K +Q G K Q G + P QQ G K Q+ + P QQ G K
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP-------- 509
Query: 491 ELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPG 550
P QQ G K QQ + P QQ G K QQ K QQ + + P
Sbjct: 510 --PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 551 QVQDIQPA 558
Q + P+
Sbjct: 568 QPPTVSPS 575
Score = 84.0 bits (206), Expect = 4e-16
Identities = 81/270 (30%), Positives = 107/270 (39%), Gaps = 18/270 (6%)
Query: 34 MKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWE 93
++QPTP PP Q+ E P+K + K L +Q K P + +
Sbjct: 306 IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP--GTVKPPVQPPGTTKPPA 363
Query: 94 QHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLL 153
Q A+ P QQ EK +Q K L + + Q G K
Sbjct: 364 Q--PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP--------GPAKP--- 410
Query: 154 ELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL 213
P QQ G K L QQ G L+ P + G + P QQ G ++P QQ G + QQ G
Sbjct: 411 --PTQQVGTPKPLAQQPG-LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467
Query: 214 ELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQL 273
+ P Q G + P QQ G + P QQ G + QQ G + QQ G K Q G
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527
Query: 274 EVPEEQMGQLKYLEQQEGQLKHLDQQEKQP 303
+ P +Q G K QQ K QQ +P
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Score = 76.6 bits (187), Expect = 6e-14
Identities = 84/351 (23%), Positives = 128/351 (36%), Gaps = 32/351 (9%)
Query: 1 MSQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVP---- 56
+ QQ P+ ++ L+ P + +Q ++ PP K P++ P + P
Sbjct: 211 LQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK-PIQGPTQTPQTDH 269
Query: 57 ---------SKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQ 107
S+ + K V+G + + P + +QQ + Q Q
Sbjct: 270 AKLPLQRDASRPQTKQADIVRG---ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Query: 108 LKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRD--EQLGMKKEQLL----ELPEQQEG 161
+ + L K L ++ + + + + LG K E P ++
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386
Query: 162 HLKHLEQQEGQLKHPEQQEGQLELPEQQEGQ---------LELPEQQEGQLELPEQQEGQ 212
K L Q G K P QQ G + P QQ G L+ P + G + P QQ G
Sbjct: 387 GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP 446
Query: 213 LELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQ 272
++P QQ G + QQ G + P Q G + QQ G + QQ G K Q G
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS 506
Query: 273 LEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQP 323
+ P +Q G K QQ G K QQ + QQ K QQ +P
Sbjct: 507 TKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Score = 44.7 bits (104), Expect = 2e-04
Identities = 90/393 (22%), Positives = 152/393 (38%), Gaps = 49/393 (12%)
Query: 25 PPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQE 84
PP + + P P QK V V++ KQE++ VK E+ ++ KE
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQE----VKTEAEKVILEKVKETLS 1181
Query: 85 QEL--QQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRD 142
E +Q +E K E + QEK K L EEKKL+ ++E ++ +
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEK--------KPLPEEKKLIP---EEEKIRSE 1230
Query: 143 EQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ-----EGQLELPEQQ-EGQLELP 196
E K+ LLE + K L E + PE+Q + Q+++ E++ EG++
Sbjct: 1231 E-----KKPLLEEKKPTPEDKKLL--PEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPK 1283
Query: 197 EQQEGQLE------LPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQE 250
QEG+ LP L + + + + Q P Q E E +E+++
Sbjct: 1284 TVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKED 1343
Query: 251 GQLEL-SEQQEGQLKHLEHQEGQLEVPEEQMGQLKYL--EQQEGQLKHLDQQEKQPELPE 307
+ + S QQ + L + +G++ L ++ LK L + E
Sbjct: 1344 DKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 308 QQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPE 367
L LE L E Q L +++ + K + E E + QE L E
Sbjct: 1404 SSPSDLAKLESTV-----LSILEAQASTLADEKSE-KKTQPHEVSPEQPKDQEKTQSLSE 1457
Query: 368 QQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQE 400
+ + + E ++ Q EE + K QQ+
Sbjct: 1458 TLEITISEEEIKESQ----EERKDTFKKDSQQD 1486
Score = 44.3 bits (103), Expect = 3e-04
Identities = 29/114 (25%), Positives = 63/114 (55%), Gaps = 5/114 (4%)
Query: 70 LPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKL 129
+PE++ +QQQ + + + L+ + +Q ++ E Q++++ + Q + K+LEE + +
Sbjct: 3204 VPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSM 3263
Query: 130 LDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQL 183
L Q+ +R Q M++E L QQ+ L+ ++Q + QL H + +E ++
Sbjct: 3264 KQHLLFQQEEERQAQFMMRQETL----AQQQLQLEQIQQLQQQL-HQQLEEQKI 3312
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/107 (31%), Positives = 63/107 (58%), Gaps = 8/107 (7%)
Query: 337 EEQEGQLKHLEQQEGQLEHLEHQE--GQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLK 394
E+++ Q LE++ +LE ++ Q +L Q++ + ++ EK Q K LEE + +
Sbjct: 3207 EDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQ-KKLEELQSMKQ 3265
Query: 395 HLV---QQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQL-KHLEEQE 437
HL+ ++E Q + +++QE L QQ+ Q+E ++Q QL + LEEQ+
Sbjct: 3266 HLLFQQEEERQAQFMMRQE-TLAQQQLQLEQIQQLQQQLHQQLEEQK 3311
Score = 38.5 bits (88), Expect = 0.017
Identities = 34/120 (28%), Positives = 65/120 (54%), Gaps = 4/120 (3%)
Query: 224 ELPEQQEGQLELPQQ--QEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMG 281
E+ + L +P++ Q+ QL+L + ++ +Q+ + E QE Q +E++
Sbjct: 3193 EVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIM 3252
Query: 282 QLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQL-EQLEEQE 340
K LE+ + +HL Q+++ E Q M + + L QQ+ Q + ++Q + QL +QLEEQ+
Sbjct: 3253 VQKKLEELQSMKQHLLFQQEE-ERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQK 3311
Score = 38.5 bits (88), Expect = 0.017
Identities = 34/131 (25%), Positives = 69/131 (52%), Gaps = 16/131 (12%)
Query: 250 EGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQ 309
E L + +++ Q + L+ + LE+ E++ Q ++ E+ E + + + + +Q ++ Q
Sbjct: 3198 ESALLIVPEEDKQQQQLDLERELLEL--EKIKQQRFAEELEWERQEIQRFREQEKIMVQ- 3254
Query: 310 MGQLKHLEQQEGQPKHL---EQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQL--G 364
K LE+ + +HL +++E Q + + QE L QQ+ QLE ++ + QL
Sbjct: 3255 ----KKLEELQSMKQHLLFQQEEERQAQFMMRQE----TLAQQQLQLEQIQQLQQQLHQQ 3306
Query: 365 LPEQQVLQLKQ 375
L EQ++ Q+ Q
Sbjct: 3307 LEEQKIRQIYQ 3317
Score = 38.1 bits (87), Expect = 0.023
Identities = 40/133 (30%), Positives = 69/133 (51%), Gaps = 16/133 (12%)
Query: 367 EQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQ 426
E +L + + +KQQ Q LE E +L+ + QQ +E + E+QE Q +++
Sbjct: 3198 ESALLIVPEEDKQQ-QQLDLERELLELEKIKQQR------FAEELEWERQEIQRFREQEK 3250
Query: 427 VGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQ 486
+ K LEE + +HL QQ + E Q + + + L Q++ QLE Q++ L++Q
Sbjct: 3251 IMVQKKLEELQSMKQHLLFQQEE-ERQAQFMMRQETLAQQQLQLE-------QIQQLQQQ 3302
Query: 487 EAQLELPEQQVGQ 499
Q +L EQ++ Q
Sbjct: 3303 LHQ-QLEEQKIRQ 3314
Score = 37.7 bits (86), Expect = 0.030
Identities = 39/130 (30%), Positives = 69/130 (53%), Gaps = 18/130 (13%)
Query: 273 LEVPEEQMGQLKY-LEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEG 331
L VPEE Q + LE++ +L+ + QQ EL E + +++ +QE K + Q++
Sbjct: 3202 LIVPEEDKQQQQLDLERELLELEKIKQQRFAEEL-EWERQEIQRFREQE---KIMVQKK- 3256
Query: 332 QLEQLEEQEGQLKHL---EQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEE 388
LEE + +HL +++E Q + + QE QQ LQL+Q+++ Q Q H +
Sbjct: 3257 ----LEELQSMKQHLLFQQEEERQAQFMMRQE----TLAQQQLQLEQIQQLQ-QQLHQQL 3307
Query: 389 EEGQLKHLVQ 398
EE +++ + Q
Sbjct: 3308 EEQKIRQIYQ 3317
Score = 37.7 bits (86), Expect = 0.030
Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 14/119 (11%)
Query: 84 EQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDE 143
E++ QQQ + E + E +QQ E+ + ++Q ++ E++K++ Q K+ E
Sbjct: 3206 EEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQ-------KKLE 3258
Query: 144 QLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQ 202
+L K+ LL E++ Q + ++ + QL+L + Q+ Q +L +Q E Q
Sbjct: 3259 ELQSMKQHLLFQQEEER-------QAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQ 3310
Score = 36.6 bits (83), Expect = 0.066
Identities = 67/343 (19%), Positives = 135/343 (39%), Gaps = 45/343 (13%)
Query: 54 EVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQH-WEQHEEYQKAENPEQQLKQEK 112
E K+E K + + ++ +++ ++H W ++ E+PE + ++ K
Sbjct: 1590 ESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETK 1649
Query: 113 TQRDQQL----------NKQLEEEKKLLDQQLDQELVKR-----DEQLGMKKEQLLELPE 157
+Q ++L K +E + D+ + K+ DE+ ++ E L + PE
Sbjct: 1650 SQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPE 1709
Query: 158 QQ---EG----HLKHLEQQEGQLKHPEQQEGQLELPEQQEG----QLELPEQQEGQLELP 206
+ EG H E P ++G Q + + G L LP
Sbjct: 1710 DRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPL-LP 1768
Query: 207 EQQEGQLELPEQQEGQLELPEQQEGQLELPQQQ-EGQLELSEQQEGQLELSEQQE----- 260
++ E E+ + EL ++QE Q E+ QQQ + + S++ + +L ++E
Sbjct: 1769 TIEDSSEE--EELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP 1826
Query: 261 -GQLKHLEHQEGQLEVPEEQMGQLKYLEQ--QEGQLKHLDQQEKQPELPEQQMGQLKHLE 317
L +E P E++ Q +E+ + ++ E PE E ++ ++
Sbjct: 1827 PSNLSPIEDAS-----PTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQ 1881
Query: 318 QQEGQPKHLEQQEGQLEQ-LEEQEGQLKHLEQQEGQLEHLEHQ 359
+ P + EQ + ++EG K L+ E E + H+
Sbjct: 1882 KVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHK 1924
Score = 35.0 bits (79), Expect = 0.19
Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 6/149 (4%)
Query: 109 KQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQ 168
+++K Q+ L ++L E +K+ Q+ +EL +++ +EQ + +++ L+ L+
Sbjct: 3206 EEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKK---LEELQS 3262
Query: 169 QEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ 228
+ L +++E Q + +QE + Q E +L +Q QLE EQ+ Q+
Sbjct: 3263 MKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLE--EQKIRQIYQYNY 3320
Query: 229 QEGQLELPQQQEGQLELSEQQEGQLELSE 257
PQ Q L E Q LE S+
Sbjct: 3321 DPSGTASPQTTTEQAIL-EGQYAALEGSQ 3348
Score = 33.9 bits (76), Expect = 0.43
Identities = 32/124 (25%), Positives = 65/124 (52%), Gaps = 5/124 (4%)
Query: 194 ELPEQQEGQLELPEQQEGQLELPEQQEG-QLELPEQQEGQLELPQQQEGQLELSEQQEGQ 252
E+ + L +PE+ + Q +L ++E +LE +QQ EL +++ EQ++
Sbjct: 3193 EVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIM 3252
Query: 253 LELS-EQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQ--PELPEQQ 309
++ E+ + +HL Q+ + + M Q + L QQ+ QL+ + Q ++Q +L EQ+
Sbjct: 3253 VQKKLEELQSMKQHLLFQQEEERQAQFMMRQ-ETLAQQQLQLEQIQQLQQQLHQQLEEQK 3311
Query: 310 MGQL 313
+ Q+
Sbjct: 3312 IRQI 3315
Score = 33.9 bits (76), Expect = 0.43
Identities = 31/141 (21%), Positives = 71/141 (50%), Gaps = 18/141 (12%)
Query: 396 LVQQEGQLKHLVQQEGQLEQQERQVEHLE-QQVGQLKHLEEQEGQLKHLEQQQGQLEVPE 454
+V E L + +++ Q +Q + + E LE +++ Q + EE E + + +++ + Q ++
Sbjct: 3194 VVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMV 3253
Query: 455 QQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPE 514
Q+ + + L+ ++ L +++E Q + + +QE L QQ+ LE +
Sbjct: 3254 QK--KLEELQSMKQHLLFQQEEERQAQFMMRQET--------------LAQQQLQLEQIQ 3297
Query: 515 QQDGQLKHLEQQEGQLKDLEQ 535
Q QL H + +E +++ + Q
Sbjct: 3298 QLQQQL-HQQLEEQKIRQIYQ 3317
Score = 33.5 bits (75), Expect = 0.56
Identities = 28/113 (24%), Positives = 59/113 (52%), Gaps = 11/113 (9%)
Query: 104 PEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHL 163
PE+ +Q++ L ++L E +K+ Q+ +EL +++ +EQ + +++ L
Sbjct: 3205 PEEDKQQQQL----DLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKK---L 3257
Query: 164 KHLEQQEGQLKHPEQQEGQLELPEQQE----GQLELPEQQEGQLELPEQQEGQ 212
+ L+ + L +++E Q + +QE QL+L + Q+ Q +L +Q E Q
Sbjct: 3258 EELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQ 3310
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/108 (27%), Positives = 61/108 (56%), Gaps = 7/108 (6%)
Query: 434 EEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELP 493
E+++ Q LE++ +LE +QQ + LE E ++++ +QE + ++K+ +L+
Sbjct: 3207 EDKQQQQLDLERELLELEKIKQQ-RFAEELEWERQEIQRFREQEKIM--VQKKLEELQSM 3263
Query: 494 EQQVGQPKHLEQQEKHLEHPE---QQDGQLKHLEQQEGQL-KDLEQQK 537
+Q + + E+Q + + E QQ QL+ ++Q + QL + LE+QK
Sbjct: 3264 KQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQK 3311
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 98.2 bits (243), Expect = 2e-20
Identities = 124/535 (23%), Positives = 197/535 (36%), Gaps = 25/535 (4%)
Query: 42 PPCQKVPVELPVEVPSKQEEKH------MTAVKGLPEQECEQQQKEPQEQELQQQHWEQH 95
P +P + ++ EE+ M+ +GLP+ E +Q+ H
Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSH 91
Query: 96 EEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLEL 155
Q P+ + + E+KL + +K + KE+
Sbjct: 92 PPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEE--HK 149
Query: 156 PEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL 215
G L + + + + + Q E ++Q+ + + EG ++
Sbjct: 150 SSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKP 209
Query: 216 PEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEV 275
P QQ+ +P+QQ G P QQ+G + Q+ + ++ Q G K ++ G +
Sbjct: 210 PLQQQPPKPIPKQQ-GPGRDPLQQDGTPKSISSQQPE-KIKSQPPGTGKPIQ---GPTQT 264
Query: 276 PEEQMGQLKYL-EQQEGQLKHLD---QQEKQPELPEQQMGQLKHL---EQQEGQPKHLEQ 328
P+ +L + Q K D + +P LP ++ + QP H +
Sbjct: 265 PQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS 324
Query: 329 QEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEE 388
Q G + + G K L QQ G ++ G P Q + K +Q G K E
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384
Query: 389 EEGQLKHLVQQEGQLKHLVQQEGQLEQQERQV---EHLEQQVGQLKHLEEQEGQLKHLEQ 445
+ G K L Q G K QQ G + +QV + L QQ G L+ + G K Q
Sbjct: 385 QPGP-KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG-LQSPAKAPGPTKTPVQ 442
Query: 446 QQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQ 505
Q G ++P QQ G K Q+ + P Q G K +Q + P QQ G K Q
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 506 QEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALP 560
Q + P QQ G K QQ G K QQ G + P+P + Q P
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Score = 85.5 bits (210), Expect = 1e-16
Identities = 114/428 (26%), Positives = 159/428 (37%), Gaps = 63/428 (14%)
Query: 154 ELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEG-----QLELPEQ 208
E ++Q+ K + EG +K P QQ+ +P+QQ G P QQ+G + PE+
Sbjct: 188 ETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQ-GPGRDPLQQDGTPKSISSQQPEK 246
Query: 209 QEGQLE-LPEQQEGQLELPEQQEGQLEL------PQQQEGQLELSEQQEGQLE------L 255
+ Q + +G + P+ +L L PQ ++ + E + L +
Sbjct: 247 IKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPI 306
Query: 256 SEQQEG-----QLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQM 310
+ G Q H + Q G + P + G K L QQ G +K Q + P Q +
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366
Query: 311 GQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQV 370
G K QQ G K +Q G K L Q G + Q G P QQV
Sbjct: 367 GPAKPPAQQTGSEKPSSEQPGP-----------KALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 371 LQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQL 430
G PK L ++ G L+ + G K VQQ G + QQ G
Sbjct: 416 ----------GTPKPLAQQPG-LQSPAKAPGPTKTPVQQPGPGKIPA-------QQAGPG 457
Query: 431 KHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQL 490
K +Q G K Q G + P QQ G K Q+ + P QQ G K
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP-------- 509
Query: 491 ELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPG 550
P QQ G K QQ + P QQ G K QQ K QQ + + P
Sbjct: 510 --PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 551 QVQDIQPA 558
Q + P+
Sbjct: 568 QPPTVSPS 575
Score = 84.0 bits (206), Expect = 4e-16
Identities = 81/270 (30%), Positives = 107/270 (39%), Gaps = 18/270 (6%)
Query: 34 MKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWE 93
++QPTP PP Q+ E P+K + K L +Q K P + +
Sbjct: 306 IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP--GTVKPPVQPPGTTKPPA 363
Query: 94 QHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLL 153
Q A+ P QQ EK +Q K L + + Q G K
Sbjct: 364 Q--PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP--------GPAKP--- 410
Query: 154 ELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL 213
P QQ G K L QQ G L+ P + G + P QQ G ++P QQ G + QQ G
Sbjct: 411 --PTQQVGTPKPLAQQPG-LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467
Query: 214 ELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQL 273
+ P Q G + P QQ G + P QQ G + QQ G + QQ G K Q G
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527
Query: 274 EVPEEQMGQLKYLEQQEGQLKHLDQQEKQP 303
+ P +Q G K QQ K QQ +P
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Score = 76.6 bits (187), Expect = 6e-14
Identities = 84/351 (23%), Positives = 128/351 (36%), Gaps = 32/351 (9%)
Query: 1 MSQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVP---- 56
+ QQ P+ ++ L+ P + +Q ++ PP K P++ P + P
Sbjct: 211 LQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK-PIQGPTQTPQTDH 269
Query: 57 ---------SKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQ 107
S+ + K V+G + + P + +QQ + Q Q
Sbjct: 270 AKLPLQRDASRPQTKQADIVRG---ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Query: 108 LKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRD--EQLGMKKEQLL----ELPEQQEG 161
+ + L K L ++ + + + + LG K E P ++
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386
Query: 162 HLKHLEQQEGQLKHPEQQEGQLELPEQQEGQ---------LELPEQQEGQLELPEQQEGQ 212
K L Q G K P QQ G + P QQ G L+ P + G + P QQ G
Sbjct: 387 GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP 446
Query: 213 LELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQ 272
++P QQ G + QQ G + P Q G + QQ G + QQ G K Q G
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS 506
Query: 273 LEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQP 323
+ P +Q G K QQ G K QQ + QQ K QQ +P
Sbjct: 507 TKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Score = 44.7 bits (104), Expect = 2e-04
Identities = 90/393 (22%), Positives = 152/393 (38%), Gaps = 49/393 (12%)
Query: 25 PPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQE 84
PP + + P P QK V V++ KQE++ VK E+ ++ KE
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQE----VKTEAEKVILEKVKETLS 1181
Query: 85 QEL--QQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRD 142
E +Q +E K E + QEK K L EEKKL+ ++E ++ +
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEK--------KPLPEEKKLIP---EEEKIRSE 1230
Query: 143 EQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ-----EGQLELPEQQ-EGQLELP 196
E K+ LLE + K L E + PE+Q + Q+++ E++ EG++
Sbjct: 1231 E-----KKPLLEEKKPTPEDKKLL--PEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPK 1283
Query: 197 EQQEGQLE------LPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQE 250
QEG+ LP L + + + + Q P Q E E +E+++
Sbjct: 1284 TVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKED 1343
Query: 251 GQLEL-SEQQEGQLKHLEHQEGQLEVPEEQMGQLKYL--EQQEGQLKHLDQQEKQPELPE 307
+ + S QQ + L + +G++ L ++ LK L + E
Sbjct: 1344 DKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 308 QQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPE 367
L LE L E Q L +++ + K + E E + QE L E
Sbjct: 1404 SSPSDLAKLESTV-----LSILEAQASTLADEKSE-KKTQPHEVSPEQPKDQEKTQSLSE 1457
Query: 368 QQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQE 400
+ + + E ++ Q EE + K QQ+
Sbjct: 1458 TLEITISEEEIKESQ----EERKDTFKKDSQQD 1486
Score = 44.3 bits (103), Expect = 3e-04
Identities = 29/114 (25%), Positives = 63/114 (55%), Gaps = 5/114 (4%)
Query: 70 LPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKL 129
+PE++ +QQQ + + + L+ + +Q ++ E Q++++ + Q + K+LEE + +
Sbjct: 3204 VPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSM 3263
Query: 130 LDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQL 183
L Q+ +R Q M++E L QQ+ L+ ++Q + QL H + +E ++
Sbjct: 3264 KQHLLFQQEEERQAQFMMRQETL----AQQQLQLEQIQQLQQQL-HQQLEEQKI 3312
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/107 (31%), Positives = 63/107 (58%), Gaps = 8/107 (7%)
Query: 337 EEQEGQLKHLEQQEGQLEHLEHQE--GQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLK 394
E+++ Q LE++ +LE ++ Q +L Q++ + ++ EK Q K LEE + +
Sbjct: 3207 EDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQ-KKLEELQSMKQ 3265
Query: 395 HLV---QQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQL-KHLEEQE 437
HL+ ++E Q + +++QE L QQ+ Q+E ++Q QL + LEEQ+
Sbjct: 3266 HLLFQQEEERQAQFMMRQE-TLAQQQLQLEQIQQLQQQLHQQLEEQK 3311
Score = 38.5 bits (88), Expect = 0.017
Identities = 34/120 (28%), Positives = 65/120 (54%), Gaps = 4/120 (3%)
Query: 224 ELPEQQEGQLELPQQ--QEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMG 281
E+ + L +P++ Q+ QL+L + ++ +Q+ + E QE Q +E++
Sbjct: 3193 EVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIM 3252
Query: 282 QLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQL-EQLEEQE 340
K LE+ + +HL Q+++ E Q M + + L QQ+ Q + ++Q + QL +QLEEQ+
Sbjct: 3253 VQKKLEELQSMKQHLLFQQEE-ERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQK 3311
Score = 38.5 bits (88), Expect = 0.017
Identities = 34/131 (25%), Positives = 69/131 (52%), Gaps = 16/131 (12%)
Query: 250 EGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQ 309
E L + +++ Q + L+ + LE+ E++ Q ++ E+ E + + + + +Q ++ Q
Sbjct: 3198 ESALLIVPEEDKQQQQLDLERELLEL--EKIKQQRFAEELEWERQEIQRFREQEKIMVQ- 3254
Query: 310 MGQLKHLEQQEGQPKHL---EQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQL--G 364
K LE+ + +HL +++E Q + + QE L QQ+ QLE ++ + QL
Sbjct: 3255 ----KKLEELQSMKQHLLFQQEEERQAQFMMRQE----TLAQQQLQLEQIQQLQQQLHQQ 3306
Query: 365 LPEQQVLQLKQ 375
L EQ++ Q+ Q
Sbjct: 3307 LEEQKIRQIYQ 3317
Score = 38.1 bits (87), Expect = 0.023
Identities = 40/133 (30%), Positives = 69/133 (51%), Gaps = 16/133 (12%)
Query: 367 EQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQ 426
E +L + + +KQQ Q LE E +L+ + QQ +E + E+QE Q +++
Sbjct: 3198 ESALLIVPEEDKQQ-QQLDLERELLELEKIKQQR------FAEELEWERQEIQRFREQEK 3250
Query: 427 VGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQ 486
+ K LEE + +HL QQ + E Q + + + L Q++ QLE Q++ L++Q
Sbjct: 3251 IMVQKKLEELQSMKQHLLFQQEE-ERQAQFMMRQETLAQQQLQLE-------QIQQLQQQ 3302
Query: 487 EAQLELPEQQVGQ 499
Q +L EQ++ Q
Sbjct: 3303 LHQ-QLEEQKIRQ 3314
Score = 37.7 bits (86), Expect = 0.030
Identities = 39/130 (30%), Positives = 69/130 (53%), Gaps = 18/130 (13%)
Query: 273 LEVPEEQMGQLKY-LEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEG 331
L VPEE Q + LE++ +L+ + QQ EL E + +++ +QE K + Q++
Sbjct: 3202 LIVPEEDKQQQQLDLERELLELEKIKQQRFAEEL-EWERQEIQRFREQE---KIMVQKK- 3256
Query: 332 QLEQLEEQEGQLKHL---EQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEE 388
LEE + +HL +++E Q + + QE QQ LQL+Q+++ Q Q H +
Sbjct: 3257 ----LEELQSMKQHLLFQQEEERQAQFMMRQE----TLAQQQLQLEQIQQLQ-QQLHQQL 3307
Query: 389 EEGQLKHLVQ 398
EE +++ + Q
Sbjct: 3308 EEQKIRQIYQ 3317
Score = 37.7 bits (86), Expect = 0.030
Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 14/119 (11%)
Query: 84 EQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDE 143
E++ QQQ + E + E +QQ E+ + ++Q ++ E++K++ Q K+ E
Sbjct: 3206 EEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQ-------KKLE 3258
Query: 144 QLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQ 202
+L K+ LL E++ Q + ++ + QL+L + Q+ Q +L +Q E Q
Sbjct: 3259 ELQSMKQHLLFQQEEER-------QAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQ 3310
Score = 36.6 bits (83), Expect = 0.066
Identities = 67/343 (19%), Positives = 135/343 (39%), Gaps = 45/343 (13%)
Query: 54 EVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQH-WEQHEEYQKAENPEQQLKQEK 112
E K+E K + + ++ +++ ++H W ++ E+PE + ++ K
Sbjct: 1590 ESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETK 1649
Query: 113 TQRDQQL----------NKQLEEEKKLLDQQLDQELVKR-----DEQLGMKKEQLLELPE 157
+Q ++L K +E + D+ + K+ DE+ ++ E L + PE
Sbjct: 1650 SQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPE 1709
Query: 158 QQ---EG----HLKHLEQQEGQLKHPEQQEGQLELPEQQEG----QLELPEQQEGQLELP 206
+ EG H E P ++G Q + + G L LP
Sbjct: 1710 DRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPL-LP 1768
Query: 207 EQQEGQLELPEQQEGQLELPEQQEGQLELPQQQ-EGQLELSEQQEGQLELSEQQE----- 260
++ E E+ + EL ++QE Q E+ QQQ + + S++ + +L ++E
Sbjct: 1769 TIEDSSEE--EELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP 1826
Query: 261 -GQLKHLEHQEGQLEVPEEQMGQLKYLEQ--QEGQLKHLDQQEKQPELPEQQMGQLKHLE 317
L +E P E++ Q +E+ + ++ E PE E ++ ++
Sbjct: 1827 PSNLSPIEDAS-----PTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQ 1881
Query: 318 QQEGQPKHLEQQEGQLEQ-LEEQEGQLKHLEQQEGQLEHLEHQ 359
+ P + EQ + ++EG K L+ E E + H+
Sbjct: 1882 KVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHK 1924
Score = 35.0 bits (79), Expect = 0.19
Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 6/149 (4%)
Query: 109 KQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQ 168
+++K Q+ L ++L E +K+ Q+ +EL +++ +EQ + +++ L+ L+
Sbjct: 3206 EEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKK---LEELQS 3262
Query: 169 QEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ 228
+ L +++E Q + +QE + Q E +L +Q QLE EQ+ Q+
Sbjct: 3263 MKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLE--EQKIRQIYQYNY 3320
Query: 229 QEGQLELPQQQEGQLELSEQQEGQLELSE 257
PQ Q L E Q LE S+
Sbjct: 3321 DPSGTASPQTTTEQAIL-EGQYAALEGSQ 3348
Score = 33.9 bits (76), Expect = 0.43
Identities = 32/124 (25%), Positives = 65/124 (52%), Gaps = 5/124 (4%)
Query: 194 ELPEQQEGQLELPEQQEGQLELPEQQEG-QLELPEQQEGQLELPQQQEGQLELSEQQEGQ 252
E+ + L +PE+ + Q +L ++E +LE +QQ EL +++ EQ++
Sbjct: 3193 EVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIM 3252
Query: 253 LELS-EQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQ--PELPEQQ 309
++ E+ + +HL Q+ + + M Q + L QQ+ QL+ + Q ++Q +L EQ+
Sbjct: 3253 VQKKLEELQSMKQHLLFQQEEERQAQFMMRQ-ETLAQQQLQLEQIQQLQQQLHQQLEEQK 3311
Query: 310 MGQL 313
+ Q+
Sbjct: 3312 IRQI 3315
Score = 33.9 bits (76), Expect = 0.43
Identities = 31/141 (21%), Positives = 71/141 (50%), Gaps = 18/141 (12%)
Query: 396 LVQQEGQLKHLVQQEGQLEQQERQVEHLE-QQVGQLKHLEEQEGQLKHLEQQQGQLEVPE 454
+V E L + +++ Q +Q + + E LE +++ Q + EE E + + +++ + Q ++
Sbjct: 3194 VVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMV 3253
Query: 455 QQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPE 514
Q+ + + L+ ++ L +++E Q + + +QE L QQ+ LE +
Sbjct: 3254 QK--KLEELQSMKQHLLFQQEEERQAQFMMRQET--------------LAQQQLQLEQIQ 3297
Query: 515 QQDGQLKHLEQQEGQLKDLEQ 535
Q QL H + +E +++ + Q
Sbjct: 3298 QLQQQL-HQQLEEQKIRQIYQ 3317
Score = 33.5 bits (75), Expect = 0.56
Identities = 28/113 (24%), Positives = 59/113 (52%), Gaps = 11/113 (9%)
Query: 104 PEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHL 163
PE+ +Q++ L ++L E +K+ Q+ +EL +++ +EQ + +++ L
Sbjct: 3205 PEEDKQQQQL----DLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKK---L 3257
Query: 164 KHLEQQEGQLKHPEQQEGQLELPEQQE----GQLELPEQQEGQLELPEQQEGQ 212
+ L+ + L +++E Q + +QE QL+L + Q+ Q +L +Q E Q
Sbjct: 3258 EELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQ 3310
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/108 (27%), Positives = 61/108 (56%), Gaps = 7/108 (6%)
Query: 434 EEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELP 493
E+++ Q LE++ +LE +QQ + LE E ++++ +QE + ++K+ +L+
Sbjct: 3207 EDKQQQQLDLERELLELEKIKQQ-RFAEELEWERQEIQRFREQEKIM--VQKKLEELQSM 3263
Query: 494 EQQVGQPKHLEQQEKHLEHPE---QQDGQLKHLEQQEGQL-KDLEQQK 537
+Q + + E+Q + + E QQ QL+ ++Q + QL + LE+QK
Sbjct: 3264 KQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQK 3311
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 97.1 bits (240), Expect = 4e-20
Identities = 137/566 (24%), Positives = 263/566 (46%), Gaps = 72/566 (12%)
Query: 32 EQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECE-QQQKEPQEQELQQQ 90
EQ++Q + K + +E+ ++ + + +K + Q E ++QKE E+ ++
Sbjct: 356 EQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEE 415
Query: 91 HWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKE 150
+ QK E ++LK E ++ + + K EEE+ L Q+L + VK++ MKK
Sbjct: 416 LEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSR--VKQEVVDVMKKS 473
Query: 151 QLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE 210
++ + Q+ H K L ++E +L + Q + E EQ + LE + + ++ ++Q+
Sbjct: 474 SEEQIAKLQKLHEKELARKEQELT-KKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQ 532
Query: 211 GQLELPE-------------------QQEGQ------LELPEQQEGQLELPQQQEGQLEL 245
L L E QQE + LEL E L+ + Q L +
Sbjct: 533 ESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAV 592
Query: 246 ---SEQQEGQLELS---EQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQ 299
+E+ + E++ E+ + +L+ L+HQ+ L + Q+ + +Y + E +L+ +Q
Sbjct: 593 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME-KLREKCEQ 651
Query: 300 EKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQ 359
EK+ L ++++ H+E E E LE+L+ ++ +L+ L + ++ H+
Sbjct: 652 EKETLLKDKEIIFQAHIE---------EMNEKTLEKLDVKQTELESLSSELSEVLKARHK 702
Query: 360 -EGQLGLPEQQVLQLKQ-LEKQQGQPK--HLEEEEGQLK-HLVQQEGQLKHLVQQEGQLE 414
E +L + + Q ++KQ LE + + K H ++ + +K H V + K L Q QLE
Sbjct: 703 LEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 762
Query: 415 --QQERQVEHLEQQVGQLKHLE----EQEGQLKHLEQ-----QQGQLEVPEQQVGQPKNL 463
+ER +HL++ +++LE EG+L+ Q Q EQ + L
Sbjct: 763 LLLKERD-KHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQL 821
Query: 464 EQ-EEKQLELPEQQEGQVKHLEKQEAQ-----LELPEQQVGQPKHLEQQEKHLEHPEQQD 517
Q ++K L+L ++ K + + EAQ EL ++ ++Q EK EQ
Sbjct: 822 AQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQ-- 879
Query: 518 GQLKHLEQ-QEGQLKDLEQQKGQLEQ 542
++K L Q E +L+D +++ Q +Q
Sbjct: 880 -KVKSLTQVYESKLEDGNKEQEQTKQ 904
Score = 95.5 bits (236), Expect = 1e-19
Identities = 129/549 (23%), Positives = 250/549 (45%), Gaps = 80/549 (14%)
Query: 53 VEVPSKQEEKHMTAVKGLPEQECEQQQKE------PQEQELQQQHWEQHEEYQKAENPEQ 106
V+V K E+ + ++ L E+E ++++E +E+E Q+Q +K+++
Sbjct: 467 VDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQ---MKVALEKSQSEYL 523
Query: 107 QLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHL 166
++ QEK Q++ ++LE +KK + + + +L ++ + ++LEL E L+
Sbjct: 524 KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQEN 583
Query: 167 EQQEGQL---------KHP-------EQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE 210
+ Q L KH E+ + +LE + Q+ L + Q + + + E
Sbjct: 584 KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME 643
Query: 211 GQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLE-LSEQQEGQLKHLEHQ 269
E EQ++ L ++ Q + + E LE + ++ +LE LS + LK
Sbjct: 644 KLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKL 703
Query: 270 EGQLEVPEEQMGQLKY-LEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQ 328
E +L V ++Q ++K LE + + K+ QQ+ + E ++ +++ E K L+
Sbjct: 704 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS----IQRTE---KALKD 756
Query: 329 QEGQLEQLEEQEGQLKHLEQQEGQLEHLE----HQEGQLGLPEQQVLQLKQLEKQQG--- 381
Q QLE L ++ KHL++ + +E+LE EG+L +Q +L + Q
Sbjct: 757 QINQLELLLKERD--KHLKEHQAHVENLEADIKRSEGEL---QQASAKLDVFQSYQSATH 811
Query: 382 -QPKHLEEEEGQL---------------KHLVQQEGQLK--------HLVQQEGQLEQQE 417
Q K EE+ QL K + + E Q K H +Q + ++Q E
Sbjct: 812 EQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLE 871
Query: 418 RQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQE 477
+Q +EQ+V L + E + + + EQ+Q + + E++ + E ++K++E+ Q+
Sbjct: 872 KQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKL 931
Query: 478 GQVK---HLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQL-KDL 533
+ H+ +E + + Q+ K ++Q+ K E Q+ K L QE +L K+L
Sbjct: 932 SAKEDSIHILNEEYETKFKNQEKKMEK-VKQKAK-----EMQETLKKKLLDQEAKLKKEL 985
Query: 534 EQQKGQLEQ 542
E +L Q
Sbjct: 986 ENTALELSQ 994
Score = 91.3 bits (225), Expect = 2e-18
Identities = 119/524 (22%), Positives = 245/524 (46%), Gaps = 65/524 (12%)
Query: 72 EQECEQQQKEPQEQELQQ-------QHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLE 124
E+E Q+Q + + QEL++ + + + + A+N +QL+Q+K + +Q+
Sbjct: 315 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMH 374
Query: 125 EEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQE-GHLKHLEQ--------QEGQLKH 175
E ++ ++++ Q L R +Q+ + E+L E E+ E + LE+ +E + K
Sbjct: 375 ETLEMKEEEIAQ-LRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKL 433
Query: 176 PEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE---GQ 232
+ + Q++ E+ + + QQE E + + E+Q +L+ ++E +
Sbjct: 434 KAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKE 493
Query: 233 LELPQQ-QEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEG 291
EL ++ Q + E EQ + LE S+ + ++ + Q+ L + E ++ + L + E
Sbjct: 494 QELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESEN 553
Query: 292 QLKHLDQQEK--QPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQ 349
+L+ L Q+ + + + E + K L++ + Q K L + E+ + + +E+
Sbjct: 554 KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHL-EAEKNKHNKEITVMVEKH 612
Query: 350 EGQLEHLEHQEGQLGLPEQQVL-QLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQ 408
+ +LE L+HQ+ L + QVL Q Q E ++ + K +E+E LK K ++
Sbjct: 613 KTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKD--------KEIIF 664
Query: 409 QEGQLEQQERQVEHLEQQVGQLKHLEEQ-----------EGQLKHLEQQQGQLEVP-EQQ 456
Q E E+ +E L+ + +L+ L + E +L L+ Q +++ E +
Sbjct: 665 QAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAK 724
Query: 457 VGQPKNLEQEEKQLELPEQQ---EGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHP 513
+ + KN Q++ + E + + K L+ Q QLEL ++ + KHL++ + H+E+
Sbjct: 725 MDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKE--RDKHLKEHQAHVENL 782
Query: 514 E----QQDGQLKHLEQQ-----------EGQLKDLEQQKGQLEQ 542
E + +G+L+ + Q K E+Q QL+Q
Sbjct: 783 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQ 826
Score = 89.7 bits (221), Expect = 7e-18
Identities = 123/569 (21%), Positives = 252/569 (44%), Gaps = 49/569 (8%)
Query: 53 VEVPSKQEE-KHMTAVKGLPEQECEQQQKEPQE--QELQQQHWEQHEEYQKAENPEQQLK 109
+E+ S E K+ K + +E Q+ + QE +E + E E+ EN +K
Sbjct: 1539 IEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMK 1598
Query: 110 QEKTQRDQQLN------KQLEEEKKLLDQQLDQELV--------KRDEQLGMKKEQLLEL 155
E + ++L K EEE K L+ +L+ E K ++++ K+QLL
Sbjct: 1599 AELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQ 1658
Query: 156 PEQQEGHLK-----HLEQQEGQLKHPEQQEGQLE-----LPEQQEGQLELPEQQEGQLEL 205
E++E K HL + +L+ E++ LE + Q L +P +
Sbjct: 1659 MEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAY 1718
Query: 206 PEQQEGQLE--LPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQL 263
EQ+E + + + E ++ + ++ + E Q+ GQ E E E+ Q + +L
Sbjct: 1719 TEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQ-EKEETVSSHFEMRCQYQERL 1777
Query: 264 KHLEHQEGQLEVPEEQMGQLKY-LEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQ-EG 321
LEH E + + +G L+ LE++ + + Q + E + + ++LE +
Sbjct: 1778 IKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDD 1837
Query: 322 QPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQG 381
K L+++E + LE++ +L ++ ++ +E +E L +++ L+Q++ +
Sbjct: 1838 VQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEE--LTSKYEKLQALQQMDGRNK 1895
Query: 382 QPKHLEE--EEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVG-QLKHLEEQEG 438
+ LEE EE HLVQ + L ++ Q LE + E +Q++G ++ L++
Sbjct: 1896 PTELLEENTEEKSKSHLVQPK-LLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLR 1954
Query: 439 QLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQV------KHLEKQEAQLEL 492
L+ QQ+ ++ E + + ++QE++ LEL + L ++E +LE+
Sbjct: 1955 MLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEM 2014
Query: 493 PEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQV 552
++ + E H E+ + LK + +++ LK ++ ++ +V
Sbjct: 2015 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKV 2074
Query: 553 QDIQPALPTKGEVLLPVEHQQQKQEVQWP 581
+D+Q L L ++QQ+ ++ + P
Sbjct: 2075 RDLQTQLEE-----LQKKYQQKLEQEENP 2098
Score = 66.2 bits (160), Expect = 8e-11
Identities = 109/499 (21%), Positives = 216/499 (43%), Gaps = 71/499 (14%)
Query: 110 QEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQ 169
+E+ Q DQQ K L+EE ++ DQ + Q+ + K++L P + LK L Q
Sbjct: 193 REELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVD-VLKPLPQL 251
Query: 170 EGQLK------------HPEQQEG----QLELPEQ----QEGQLE-----LPEQQEGQLE 204
E Q + P ++G LE +Q QE L+ + +E
Sbjct: 252 EPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTL 311
Query: 205 LPEQQEGQLELPEQQEGQLELPE---------------QQEGQLELPQQQEGQL--ELSE 247
L ++E E +++ +LE + + +E +Q +G + E
Sbjct: 312 LTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKR 371
Query: 248 QQEGQLELSEQQEGQL----KHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQP 303
Q LE+ E++ QL K + Q +L +E+ + + E ++ +E +
Sbjct: 372 QMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARR 431
Query: 304 ELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQL 363
+L + Q+K +E+ + + QQE + E + K E+Q +L+ L +E L
Sbjct: 432 KLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKE--L 489
Query: 364 GLPEQQV---LQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLE------ 414
EQ++ LQ ++ E Q+ LE+ + + + Q++ Q + L +E +L+
Sbjct: 490 ARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILT 549
Query: 415 QQERQVEHLEQQVG--QLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLEL 472
+ E ++ L+Q+ + + LE + K L++ + Q + + KN +E + +
Sbjct: 550 ESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITV-M 608
Query: 473 PEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQL---------KHL 523
E+ + +++ L+ Q+ L + QV + ++ + EK E EQ+ L H+
Sbjct: 609 VEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHI 668
Query: 524 EQ-QEGQLKDLEQQKGQLE 541
E+ E L+ L+ ++ +LE
Sbjct: 669 EEMNEKTLEKLDVKQTELE 687
Score = 65.1 bits (157), Expect = 2e-10
Identities = 101/457 (22%), Positives = 207/457 (45%), Gaps = 59/457 (12%)
Query: 105 EQQLKQEKTQRD------QQLNKQLEE-EKKLLDQQLDQE-LVKRDEQLGMKKEQLLELP 156
E QL+Q +++ QQ QLEE E ++ + D E LV E L + +
Sbjct: 1275 EAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAA 1334
Query: 157 EQQEGHLKHLEQQEGQ------LKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE 210
++E + L+++ + L E +E ++E+ + +L Q + + L E++
Sbjct: 1335 SEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEA 1394
Query: 211 GQLELPEQ-QEGQLELPEQ-QEGQLELPQQQEGQLELSEQ-QEGQLELSE-QQEGQLKHL 266
L +Q E + EL +Q Q+ ++ + ++ EQ + + SE +++ Q +
Sbjct: 1395 AISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFT 1454
Query: 267 EHQEG--QLEVPEEQMGQLKYLEQQEGQL--KHLDQQEKQPELPEQQMGQLKHLEQQEGQ 322
+HQ +L++ E + Y + ++ L + LDQQ K+ + + +M E
Sbjct: 1455 QHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEM---------EDD 1505
Query: 323 PKHLEQQEGQLE-QLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQG 381
+E++E LE +L+ Q ++ LE +H+ + ++ L ++ K
Sbjct: 1506 KSKMEKKESNLETELKSQTARIMELE------DHITQK-------TIEIESLNEVLKNYN 1552
Query: 382 QPKHLEEEEGQLKHLVQQEGQLKHL-VQQEGQLEQQERQVEHLEQQVGQLK-HLEEQEGQ 439
Q K +E +E LVQ+ + L +++ ++++ E ++ LE QV +K LE ++ +
Sbjct: 1553 QQKDIEHKE-----LVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKE 1607
Query: 440 LKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQ-EAQLELPEQQV- 497
L+H+ E + + E K EL + E ++ ++KQ +Q+E E+Q
Sbjct: 1608 LEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYK 1667
Query: 498 -GQPKHLEQQEKHLEHPEQQ----DGQLKHLEQQEGQ 529
G HL + L+ E++ + +LK +E + +
Sbjct: 1668 KGTESHLSELNTKLQEREREVHILEEKLKSVESSQSE 1704
Score = 58.9 bits (141), Expect = 1e-08
Identities = 110/512 (21%), Positives = 208/512 (40%), Gaps = 46/512 (8%)
Query: 28 NTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQEL 87
N QEQ KQ +K + L + K+E + +T E +E E +
Sbjct: 896 NKEQEQTKQIL-----VEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEE-YETKF 949
Query: 88 QQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGM 147
+ Q + + QKA+ ++ LK++ ++ +L K+LE L Q+ Q K E
Sbjct: 950 KNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQA 1009
Query: 148 KKEQLLELPEQQEGHLKHLEQQEGQLK-HPEQQEGQLELPEQQEGQL--ELPEQQEGQLE 204
+ + + E + K EQ E + H + + + E++ Q EL E E QL+
Sbjct: 1010 NSAGISDAVSRLETNQK--EQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQ 1067
Query: 205 LPEQQEGQLELP------EQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQ 258
EQ+ +L+ E++E E+ +E ++ E +Q+ + Q
Sbjct: 1068 EKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQ 1127
Query: 259 QEGQLK-HLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQP--------ELPEQQ 309
E +LK HLE E L + + + +L++Q +LK L +++K+ + +++
Sbjct: 1128 DETKLKAHLEKLEVDL---NKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEE 1184
Query: 310 MGQLKHLEQQEGQPKHLEQQEGQLEQLEEQ---------EGQLKHLEQQEGQLEHLEHQE 360
LK E K LE + + ++L E+ + LE + +L ++ +
Sbjct: 1185 FQSLK--SSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSK 1242
Query: 361 GQLGLPEQQVLQLKQLEKQQG---QPKHLEEEEGQLKHLVQQEGQLKHLVQQ-EGQLEQQ 416
L Q + + ++ + + E E QL+ L +++ L QQ QLE++
Sbjct: 1243 TNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEK 1302
Query: 417 ERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQ 476
E Q++ ++ + L + E+E K QQ E + Q K E ++
Sbjct: 1303 ENQIKSMKADIESL--VTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKE 1360
Query: 477 EGQVKHLEKQEAQLELPEQQVGQPKHLEQQEK 508
E + K +E +L + V + EK
Sbjct: 1361 ELKEKKVEISSLSKQLTDLNVQLQNSISLSEK 1392
Score = 38.5 bits (88), Expect = 0.017
Identities = 51/240 (21%), Positives = 109/240 (45%), Gaps = 21/240 (8%)
Query: 48 PVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQ 107
P EL E ++ + H+ K L E + E + +++ + +E + + +
Sbjct: 1896 PTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRM 1955
Query: 108 LKQEKTQRDQQLNKQLEEEK--KLLDQQLDQELVKRDEQLGM----------KKEQLLEL 155
L++E Q + L K+ ++E+ K+ +Q D EL K + L +KEQ LE+
Sbjct: 1956 LRKEHQQELEILKKEYDQEREEKIKQEQEDLEL-KHNSTLKQLMREFNTQLAQKEQELEM 2014
Query: 156 PEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL 215
++ + ++ E +L Q+E L + E +L + E+ + +E ++
Sbjct: 2015 TIKET--INKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM-T 2071
Query: 216 PEQQEGQLELPE-QQEGQLELPQQQEGQLELSEQQEGQLELSEQ----QEGQLKHLEHQE 270
+ ++ Q +L E Q++ Q +L Q++ + E Q +L+++ + +LK E +E
Sbjct: 2072 AKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFRE 2131
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 94.4 bits (233), Expect = 3e-19
Identities = 105/423 (24%), Positives = 204/423 (48%), Gaps = 58/423 (13%)
Query: 130 LDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQ 189
+DQ+L +E V DEQ ++K+ + ++ K + G LEL +++
Sbjct: 325 VDQRLPEEPVLEDEQQQLEKKLPVTFEDK---------------KRENFERGNLELEKRR 369
Query: 190 EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ-EGQLELPQQQEGQLELSEQ 248
+ LE +++ +L QLE EQ+ + E EQ+ + QLEL +Q E Q EL Q
Sbjct: 370 QALLEQQRKEQERL-------AQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQ 422
Query: 249 QEGQLELS-EQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQ-LKHLDQQEKQPELP 306
+E + E++E + LE Q QLE + +L +E + + L ++K E
Sbjct: 423 REEERRKEIERREAAKRELERQR-QLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFE 481
Query: 307 EQQMGQLKHLEQQEGQPK----HLEQQEGQLEQLEEQE----GQLKHLEQQEGQLEHLEH 358
+ + KH Q EG+ + L Q ++E + ++ HL+QQ L+ +
Sbjct: 482 LEALNDKKH--QLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQ---LQESQQ 536
Query: 359 QEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQER 418
G+L +PE+Q+L QL++ Q H + + L +E +HL Q ++E++ R
Sbjct: 537 MLGRL-IPEKQILN-DQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETR 594
Query: 419 QVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEG 478
+L+ ++ QLK L + + ++ +Q+ + + L+Q+E++ ++ E ++
Sbjct: 595 S---------KLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEK- 644
Query: 479 QVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKG 538
+K+EAQ E+ +H++Q+++H + P + + K L+++E K ++KG
Sbjct: 645 -----QKEEAQRRAQERDKQWLEHVQQEDEH-QRPRKLHEEEK-LKREESVKKKDGEEKG 697
Query: 539 QLE 541
+ E
Sbjct: 698 KQE 700
Score = 89.7 bits (221), Expect = 7e-18
Identities = 98/423 (23%), Positives = 215/423 (50%), Gaps = 27/423 (6%)
Query: 45 QKVPVELPVEV--PSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHE----EY 98
Q +P LP E PS + + + + + +Q+ E E +QQ E+ E
Sbjct: 293 QPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFED 352
Query: 99 QKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLD-QQLDQELVKRDEQLGMKKEQL-LELP 156
+K EN E+ + + +R L +Q +E+++L ++ +QE +R+ Q +K QL LE
Sbjct: 353 KKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQ 412
Query: 157 EQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELP 216
+++ L+ ++E + + ++ + EL Q++ + E +QE + ++QE + L
Sbjct: 413 LEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLK 472
Query: 217 EQQ---EGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQL 273
++ E +LE ++ QLE + Q+ + L+ Q++ ++ +E ++ + H + QL
Sbjct: 473 AKKKTLEFELEALNDKKHQLE-GKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQL 531
Query: 274 EVPEEQMGQLKYLEQ-QEGQLKHLDQQEKQPELPEQQMGQLKH-LEQQEGQPKHLEQQEG 331
+ ++ +G+L +Q QLK Q +Q L + LK LE +E +HL Q
Sbjct: 532 QESQQMLGRLIPEKQILNDQLK----QVQQNSLHRDSLVTLKRALEAKELARQHLRDQLD 587
Query: 332 QLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLE---- 387
++E +E +L+ ++ QL+ L + L +Q+ ++ ++L++++ + K +E
Sbjct: 588 EVE--KETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQ 645
Query: 388 EEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQ 447
+EE Q + + + L+H+ Q++ E Q + H E+++ + + +++++G+ K ++ Q
Sbjct: 646 KEEAQRRAQERDKQWLEHVQQED---EHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQ 702
Query: 448 GQL 450
+L
Sbjct: 703 DKL 705
Score = 81.3 bits (199), Expect = 2e-15
Identities = 95/396 (23%), Positives = 188/396 (47%), Gaps = 52/396 (13%)
Query: 45 QKVPVELPVEVPSKQEEKHMTAV---KGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKA 101
Q++P E +E +Q EK + K E + E + Q L +Q ++ E +
Sbjct: 327 QRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQL 386
Query: 102 ENPEQQLKQEKTQ-----RDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELP 156
E EQ+ K+ + Q R +L KQLE++++ L++Q ++E R +++ ++ EL
Sbjct: 387 ERAEQERKERERQEQERKRQLELEKQLEKQRE-LERQREEE---RRKEIERREAAKRELE 442
Query: 157 EQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQ---EGQLELPEQQEGQLE--------- 204
Q++ + +QE + ++QE + L ++ E +LE ++ QLE
Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCR 502
Query: 205 -LPEQQE-------GQLELPEQQEGQLELPEQQE--GQLELPQQQEGQLELSEQQEGQLE 254
++QE +L + E Q +L E Q+ G+L +P++Q +L + Q+ L
Sbjct: 503 LTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRL-IPEKQILNDQLKQVQQNSLH 561
Query: 255 ------LSEQQEGQLKHLEHQEGQL-EVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPE 307
L E + +H QL EV +E +L+ ++ QLK L + + +L +
Sbjct: 562 RDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQK 621
Query: 308 QQMGQLKHLEQQEGQPKHLE----QQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQL 363
Q+ + + L+Q+E + K +E ++E Q E + L+H++Q++ EHQ +
Sbjct: 622 QKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQED------EHQRPRK 675
Query: 364 GLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQ 399
E+++ + + ++K+ G+ K +E + +L L Q
Sbjct: 676 LHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQ 711
Score = 57.0 bits (136), Expect = 5e-08
Identities = 64/310 (20%), Positives = 138/310 (44%), Gaps = 48/310 (15%)
Query: 61 EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQL- 119
EK + + L Q E+++KE + +E ++ E+ + + N Q+L ++ + + +
Sbjct: 410 EKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIV 469
Query: 120 -----NKQLEEEKKLLDQ---QLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEG 171
K LE E + L+ QL+ +L +L +++++ + +E + + +
Sbjct: 470 VLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529
Query: 172 QLKHPEQQEGQLELPEQQEGQLELPEQQEGQL---------------ELPEQQ-EGQL-E 214
QL+ +Q G+L +PE+Q +L + Q+ L EL Q QL E
Sbjct: 530 QLQESQQMLGRL-IPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDE 588
Query: 215 LPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLE----HQE 270
+ ++ +L+ + QL+ ++ + +L +Q+ + E +Q+E + K +E +E
Sbjct: 589 VEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEE 648
Query: 271 GQLEVPEEQMGQLKYLEQQ-----------------EGQLKHLDQQEKQPELPEQQMGQL 313
Q E L++++Q+ E +K D +EK + + ++G+L
Sbjct: 649 AQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRL 708
Query: 314 KHLEQQEGQP 323
H Q+ +P
Sbjct: 709 FHQHQEPAKP 718
Score = 52.8 bits (125), Expect = 9e-07
Identities = 58/219 (26%), Positives = 107/219 (48%), Gaps = 16/219 (7%)
Query: 365 LPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLE 424
LPE+ VL+ +Q + ++ P E++ K + G L+ +++ LEQQ ++ E L
Sbjct: 329 LPEEPVLEDEQQQLEKKLPVTFEDK----KRENFERGNLELEKRRQALLEQQRKEQERL- 383
Query: 425 QQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLE---QEEKQLELPEQQEGQVK 481
QL+ E++ + + EQ++ + E+Q+ + + LE +EE++ E+ E++E +
Sbjct: 384 ---AQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEI-ERREAAKR 439
Query: 482 HLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLE 541
LE+Q QLE + + + L Q+ K E + K LE + L D + Q
Sbjct: 440 ELERQR-QLEWERNR--RQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKL 496
Query: 542 QPVFAPAPGQVQDIQPALPTKGEVLLPVEH-QQQKQEVQ 579
Q + Q Q+I+ ++ + + H QQQ QE Q
Sbjct: 497 QDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQ 535
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 94.4 bits (233), Expect = 3e-19
Identities = 105/423 (24%), Positives = 204/423 (48%), Gaps = 58/423 (13%)
Query: 130 LDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQ 189
+DQ+L +E V DEQ ++K+ + ++ K + G LEL +++
Sbjct: 325 VDQRLPEEPVLEDEQQQLEKKLPVTFEDK---------------KRENFERGNLELEKRR 369
Query: 190 EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ-EGQLELPQQQEGQLELSEQ 248
+ LE +++ +L QLE EQ+ + E EQ+ + QLEL +Q E Q EL Q
Sbjct: 370 QALLEQQRKEQERL-------AQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQ 422
Query: 249 QEGQLELS-EQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQ-LKHLDQQEKQPELP 306
+E + E++E + LE Q QLE + +L +E + + L ++K E
Sbjct: 423 REEERRKEIERREAAKRELERQR-QLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFE 481
Query: 307 EQQMGQLKHLEQQEGQPK----HLEQQEGQLEQLEEQE----GQLKHLEQQEGQLEHLEH 358
+ + KH Q EG+ + L Q ++E + ++ HL+QQ L+ +
Sbjct: 482 LEALNDKKH--QLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQ---LQESQQ 536
Query: 359 QEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQER 418
G+L +PE+Q+L QL++ Q H + + L +E +HL Q ++E++ R
Sbjct: 537 MLGRL-IPEKQILN-DQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEVEKETR 594
Query: 419 QVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEG 478
+L+ ++ QLK L + + ++ +Q+ + + L+Q+E++ ++ E ++
Sbjct: 595 S---------KLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEK- 644
Query: 479 QVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKG 538
+K+EAQ E+ +H++Q+++H + P + + K L+++E K ++KG
Sbjct: 645 -----QKEEAQRRAQERDKQWLEHVQQEDEH-QRPRKLHEEEK-LKREESVKKKDGEEKG 697
Query: 539 QLE 541
+ E
Sbjct: 698 KQE 700
Score = 89.7 bits (221), Expect = 7e-18
Identities = 98/423 (23%), Positives = 215/423 (50%), Gaps = 27/423 (6%)
Query: 45 QKVPVELPVEV--PSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHE----EY 98
Q +P LP E PS + + + + + +Q+ E E +QQ E+ E
Sbjct: 293 QPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFED 352
Query: 99 QKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLD-QQLDQELVKRDEQLGMKKEQL-LELP 156
+K EN E+ + + +R L +Q +E+++L ++ +QE +R+ Q +K QL LE
Sbjct: 353 KKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQ 412
Query: 157 EQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELP 216
+++ L+ ++E + + ++ + EL Q++ + E +QE + ++QE + L
Sbjct: 413 LEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLK 472
Query: 217 EQQ---EGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQL 273
++ E +LE ++ QLE + Q+ + L+ Q++ ++ +E ++ + H + QL
Sbjct: 473 AKKKTLEFELEALNDKKHQLE-GKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQL 531
Query: 274 EVPEEQMGQLKYLEQ-QEGQLKHLDQQEKQPELPEQQMGQLKH-LEQQEGQPKHLEQQEG 331
+ ++ +G+L +Q QLK Q +Q L + LK LE +E +HL Q
Sbjct: 532 QESQQMLGRLIPEKQILNDQLK----QVQQNSLHRDSLVTLKRALEAKELARQHLRDQLD 587
Query: 332 QLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLE---- 387
++E +E +L+ ++ QL+ L + L +Q+ ++ ++L++++ + K +E
Sbjct: 588 EVE--KETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQ 645
Query: 388 EEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQ 447
+EE Q + + + L+H+ Q++ E Q + H E+++ + + +++++G+ K ++ Q
Sbjct: 646 KEEAQRRAQERDKQWLEHVQQED---EHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQ 702
Query: 448 GQL 450
+L
Sbjct: 703 DKL 705
Score = 81.3 bits (199), Expect = 2e-15
Identities = 95/396 (23%), Positives = 188/396 (47%), Gaps = 52/396 (13%)
Query: 45 QKVPVELPVEVPSKQEEKHMTAV---KGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKA 101
Q++P E +E +Q EK + K E + E + Q L +Q ++ E +
Sbjct: 327 QRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQL 386
Query: 102 ENPEQQLKQEKTQ-----RDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELP 156
E EQ+ K+ + Q R +L KQLE++++ L++Q ++E R +++ ++ EL
Sbjct: 387 ERAEQERKERERQEQERKRQLELEKQLEKQRE-LERQREEE---RRKEIERREAAKRELE 442
Query: 157 EQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQ---EGQLELPEQQEGQLE--------- 204
Q++ + +QE + ++QE + L ++ E +LE ++ QLE
Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCR 502
Query: 205 -LPEQQE-------GQLELPEQQEGQLELPEQQE--GQLELPQQQEGQLELSEQQEGQLE 254
++QE +L + E Q +L E Q+ G+L +P++Q +L + Q+ L
Sbjct: 503 LTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRL-IPEKQILNDQLKQVQQNSLH 561
Query: 255 ------LSEQQEGQLKHLEHQEGQL-EVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPE 307
L E + +H QL EV +E +L+ ++ QLK L + + +L +
Sbjct: 562 RDSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQK 621
Query: 308 QQMGQLKHLEQQEGQPKHLE----QQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQL 363
Q+ + + L+Q+E + K +E ++E Q E + L+H++Q++ EHQ +
Sbjct: 622 QKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQED------EHQRPRK 675
Query: 364 GLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQ 399
E+++ + + ++K+ G+ K +E + +L L Q
Sbjct: 676 LHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQ 711
Score = 57.0 bits (136), Expect = 5e-08
Identities = 64/310 (20%), Positives = 138/310 (44%), Gaps = 48/310 (15%)
Query: 61 EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQL- 119
EK + + L Q E+++KE + +E ++ E+ + + N Q+L ++ + + +
Sbjct: 410 EKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIV 469
Query: 120 -----NKQLEEEKKLLDQ---QLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEG 171
K LE E + L+ QL+ +L +L +++++ + +E + + +
Sbjct: 470 VLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529
Query: 172 QLKHPEQQEGQLELPEQQEGQLELPEQQEGQL---------------ELPEQQ-EGQL-E 214
QL+ +Q G+L +PE+Q +L + Q+ L EL Q QL E
Sbjct: 530 QLQESQQMLGRL-IPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDE 588
Query: 215 LPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLE----HQE 270
+ ++ +L+ + QL+ ++ + +L +Q+ + E +Q+E + K +E +E
Sbjct: 589 VEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEE 648
Query: 271 GQLEVPEEQMGQLKYLEQQ-----------------EGQLKHLDQQEKQPELPEQQMGQL 313
Q E L++++Q+ E +K D +EK + + ++G+L
Sbjct: 649 AQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRL 708
Query: 314 KHLEQQEGQP 323
H Q+ +P
Sbjct: 709 FHQHQEPAKP 718
Score = 52.8 bits (125), Expect = 9e-07
Identities = 58/219 (26%), Positives = 107/219 (48%), Gaps = 16/219 (7%)
Query: 365 LPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLE 424
LPE+ VL+ +Q + ++ P E++ K + G L+ +++ LEQQ ++ E L
Sbjct: 329 LPEEPVLEDEQQQLEKKLPVTFEDK----KRENFERGNLELEKRRQALLEQQRKEQERL- 383
Query: 425 QQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLE---QEEKQLELPEQQEGQVK 481
QL+ E++ + + EQ++ + E+Q+ + + LE +EE++ E+ E++E +
Sbjct: 384 ---AQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEI-ERREAAKR 439
Query: 482 HLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLE 541
LE+Q QLE + + + L Q+ K E + K LE + L D + Q
Sbjct: 440 ELERQR-QLEWERNR--RQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKL 496
Query: 542 QPVFAPAPGQVQDIQPALPTKGEVLLPVEH-QQQKQEVQ 579
Q + Q Q+I+ ++ + + H QQQ QE Q
Sbjct: 497 QDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQ 535
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 92.8 bits (229), Expect = 8e-19
Identities = 161/634 (25%), Positives = 259/634 (40%), Gaps = 123/634 (19%)
Query: 15 LSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQE 74
L Q LK + + H++ K +K E P E +K + EQ+
Sbjct: 3520 LLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFP--------EADAEKLKLVTEQQ 3571
Query: 75 CEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQL 134
+ Q++ Q ++ Q++H EY+ + +QQ +Q++ Q+ + + L +L
Sbjct: 3572 SKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKL 3631
Query: 135 DQELVKRDEQLGMKKEQ---------------LLELPEQQEG-----HLKHLEQQE---- 170
+L+ G++ Q + LP Q G L +QQ+
Sbjct: 3632 PGQLLPGH---GLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGG 3688
Query: 171 -GQLKHPEQQ--EGQLEL----PEQ---QEGQLELPEQQEGQLELPEQQEGQLELPEQQE 220
G L P G L L P+ QE QL+L +Q+ + +QQ+ Q + +
Sbjct: 3689 AGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLL 3748
Query: 221 GQLELPEQQE---------------GQLELPQQQEGQL--ELSEQ----QEGQL------ 253
GQ+ + +QQ+ L P +G L +LS Q +G L
Sbjct: 3749 GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVA 3808
Query: 254 ELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKH---LDQQEKQPELPEQQ- 309
L +Q G L L + + +Q +G + H QQ++Q + +QQ
Sbjct: 3809 VLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQG 3868
Query: 310 -MGQLKHLEQ----QEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLG 364
M L HL+Q GQPK Q G L+QL++Q+ QL QQ+ QL+ + Q+
Sbjct: 3869 SMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQ-QL----QQQQQLQQQQQQQ---- 3919
Query: 365 LPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLE 424
L +QQ LQ +QL++QQ Q + ++++ QL+ QQ+ QL QQ+ Q +QQ+ Q + +
Sbjct: 3920 LQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ---QQQQQL----QQQQQQQQQQFQQQQQQ 3972
Query: 425 QQVGQLKH----LEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQV 480
QQ+G L L Q+ Q + + G P Q P L L L +++ V
Sbjct: 3973 QQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGAL---GPTLLLTGKEQNTV 4029
Query: 481 KHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL 540
EA E P G P + E + G++K + QL L
Sbjct: 4030 DPAVSSEA-TEGPSTHQGGPLAIGTTP---ESMATEPGEVKPSLSGDSQL--------LL 4077
Query: 541 EQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQ 574
QP P P +Q +QP L LP + QQQ
Sbjct: 4078 VQPQPQPQPSSLQ-LQPPL------RLPGQQQQQ 4104
Score = 90.1 bits (222), Expect = 5e-18
Identities = 160/661 (24%), Positives = 262/661 (39%), Gaps = 105/661 (15%)
Query: 3 QQHTLPVTLSPALSQELLKTVP--------------PPVNTHQEQMKQPTPLPPPCQKVP 48
QQH+ + LSP+ S LL +P PP P + P Q
Sbjct: 3611 QQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGG 3670
Query: 49 VELPVEVPSKQEEKHMTAVKGLP-------EQECEQQQKEPQEQELQQQHWE-QHEEYQK 100
L + +Q+++H L + P + LQ++ + Q + Q
Sbjct: 3671 PFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQL 3730
Query: 101 AENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQE 160
A+ +QQ Q+ QQ + L + + QQ V+ ++ LG K + L+ Q
Sbjct: 3731 AQKLQQQ------QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQG 3784
Query: 161 GHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE-GQLELPEQQ 219
++ L Q Q Q+ + +QQ P+ Q+ + + + +L +Q
Sbjct: 3785 LLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQG 3844
Query: 220 EGQLE---LPEQQEGQLELPQQQEGQLELSEQQE------GQLELSEQQEGQLKHLEHQ- 269
+G + + QQ+ Q + QQQ LS Q+ GQ +LS Q G L+ L+ Q
Sbjct: 3845 QGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQ 3904
Query: 270 --EGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLE 327
+ Q ++ ++Q QL+ +QQ+ Q + L QQ++Q +L +QQ Q L+
Sbjct: 3905 QLQQQQQLQQQQQQQLQ--QQQQLQQQQLQQQQQQQQLQQQQQQQ-------------LQ 3949
Query: 328 QQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLE 387
QQ+ QL+Q ++Q+ Q +QQ+ Q+ L L +QQ Q+ +P
Sbjct: 3950 QQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHF 4009
Query: 388 EEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQL------KHLEEQEGQLK 441
G L + G+ ++ V E E H Q G L + + + G++K
Sbjct: 4010 SSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTH---QGGPLAIGTTPESMATEPGEVK 4066
Query: 442 -HLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHL--------------EKQ 486
L L V Q QP +L Q + L LP QQ+ QV L
Sbjct: 4067 PSLSGDSQLLLVQPQPQPQPSSL-QLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSS 4125
Query: 487 EAQ-----LELPEQQVG-QPKHLEQ-----QEKHLEHPEQQDGQLKHLEQ----QEGQ-- 529
EA L P +G QP + Q Q+ LE P Q + + + Q GQ
Sbjct: 4126 EASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL 4185
Query: 530 -----LKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKH 584
+ + Q + QL Q V A P Q++ + P + + LL QQ Q V+ P +
Sbjct: 4186 PGVGIMPTVGQLRAQL-QGVLAKNP-QLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPY 4243
Query: 585 K 585
+
Sbjct: 4244 Q 4244
Score = 61.2 bits (147), Expect = 2e-09
Identities = 131/564 (23%), Positives = 214/564 (37%), Gaps = 59/564 (10%)
Query: 9 VTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVK 68
V SP L+Q+ + + T Q+Q +Q L + S + ++A
Sbjct: 3834 VLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQP 3893
Query: 69 GLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKK 128
Q+ +QQQ+ Q+Q+LQQQ +Q ++ +QQL+Q++ Q+ QQ
Sbjct: 3894 MGSLQQLQQQQQLQQQQQLQQQQQQQLQQ-------QQQLQQQQLQQQQQ---------- 3936
Query: 129 LLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQ 188
QQL Q+ + +QL +++QL +QQ +QQ+ Q +QQ+ Q+ L Q
Sbjct: 3937 --QQQLQQQ---QQQQLQQQQQQL----QQQ-------QQQQQQQFQQQQQQQQMGLLNQ 3980
Query: 189 QEGQLELPEQQEGQLEL----PEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLE 244
L +QQ+ Q+ L P + P L L +++ ++ E
Sbjct: 3981 SRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEG 4040
Query: 245 LSEQQEGQLELSEQQE------GQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQ 298
S Q G L + E G++K + QL + + Q Q + L+ Q
Sbjct: 4041 PSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQ 4100
Query: 299 QEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQ----LEEQEGQLKH--LEQQEGQ 352
Q++Q L G H + G L Q L +Q G + L Q+
Sbjct: 4101 QQQQVSLLHTAGGG-SHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPM 4159
Query: 353 LEH-LEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEG 411
LE +++ G VLQ Q G + + QL+ ++ + QL+HL Q+
Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219
Query: 412 QLEQ---QERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEK 468
Q Q +RQ++ Q V Q +E Q L QG L Q G P +
Sbjct: 4220 QQLQALLMQRQLQQ-SQAVRQTPPYQEPGTQTSPL---QGLLGCQPQLGGFPGPQTGPLQ 4275
Query: 469 QLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEG 528
+L + +G + A P P + + P Q L E
Sbjct: 4276 ELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL-PTEA 4334
Query: 529 QLKDLEQQKGQLEQPVFAPAPGQV 552
QL + + P P PG+V
Sbjct: 4335 QLPPTHPGTPKPQGPTLEPPPGRV 4358
Score = 51.6 bits (122), Expect = 2e-06
Identities = 99/419 (23%), Positives = 168/419 (40%), Gaps = 69/419 (16%)
Query: 227 EQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYL 286
+ +E Q + QL++ E+Q G S + + + G+ E PE +LK +
Sbjct: 3509 QYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGR-EFPEADAEKLKLV 3567
Query: 287 EQQEGQL-KHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQL----------EQ 335
+Q+ ++ K LDQ KQ + M + ++ +QQ+ Q + +QQ+
Sbjct: 3568 TEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRL 3627
Query: 336 LEEQEGQL---KHLEQQE----GQLEHLEHQEGQLGLPEQ-------QVLQLKQLEKQQG 381
L + GQL L+ + GQ L G + LP Q L +Q ++ G
Sbjct: 3628 LTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSG 3687
Query: 382 QPKHLEEEEGQL---KHLVQQEGQLKHLVQQ-EGQLEQQERQV-EHLEQQVGQLKHLEEQ 436
L G ++ G L+Q+ + QL+QQ Q+ + L+QQ Q + +
Sbjct: 3688 GAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHL 3747
Query: 437 EGQLKHLEQQQGQLEVPEQQVGQPK-----------NLEQEEKQLELPEQQEG-----QV 480
GQ+ +QQQ V Q PK L ++ + P+ +G QV
Sbjct: 3748 LGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQV 3807
Query: 481 KHLEKQ----------EAQLELPEQQVGQPKHLEQQEK-----HLEHPEQQDGQLKHLEQ 525
L++Q Q+ + + +V L QQ + L +QQ Q +H Q
Sbjct: 3808 AVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQH--Q 3865
Query: 526 QEGQLKDLEQQKGQL----EQPVFAPAP-GQVQDIQPALPTKGEVLLPVEHQQQKQEVQ 579
Q+G + L + L QP + P G +Q +Q + + L + QQQ Q+ Q
Sbjct: 3866 QQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQ 3924
Score = 43.5 bits (101), Expect = 5e-04
Identities = 99/452 (21%), Positives = 174/452 (38%), Gaps = 54/452 (11%)
Query: 153 LELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQ 212
L LP L++ E L E +L E ++ +L+ +Q QL+ +QQ+ Q
Sbjct: 3220 LTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQ 3279
Query: 213 LELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELS-EQQEGQLKHLEHQEG 271
+QQ L P + + LP + QQ+ L L+ +Q G + L +
Sbjct: 3280 ----QQQHSLLSAPGPAQA-MSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQP 3334
Query: 272 QLEVPEEQMGQLKYLEQQEGQL---KH------LDQQEKQPELPEQQMGQLKHLEQQEGQ 322
++++ + +G + +H + QQ QP L ++ MG + + Q
Sbjct: 3335 PAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQ 3394
Query: 323 PKHLEQQ-------EGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQ------LGLPEQQ 369
++QQ + L++ ++ + + L+ ++ Q G+ QQ
Sbjct: 3395 QLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQ 3454
Query: 370 VLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQ 429
V L Q + G P H+ GQ + G Q Q V
Sbjct: 3455 VSLLAQ--RLSGGP-----SSDLQNHVAAGSGQ----ERSAGDPSQPRPNPPTFAQGVIN 3503
Query: 430 LKHLEEQEGQLKHLEQ-QQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEA 488
+ E L H +Q Q QL+V E+Q+G + ++ ++ +Q+ + E EA
Sbjct: 3504 EADQRQYEEWLFHTQQLLQMQLKVLEEQIG----VHRKSRKALCAKQRTAKKAGREFPEA 3559
Query: 489 QLE----LPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPV 544
E + EQQ K L+Q K + + ++ +QQ+ Q +QQ+ Q V
Sbjct: 3560 DAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQ---QQQQQQQQHSAV 3616
Query: 545 FAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQ 576
A +P Q + LP + LLP Q Q
Sbjct: 3617 LALSPSQSPRLLTKLPGQ---LLPGHGLQPPQ 3645
Score = 39.7 bits (91), Expect = 0.008
Identities = 67/279 (24%), Positives = 105/279 (37%), Gaps = 20/279 (7%)
Query: 11 LSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGL 70
LSP + L PPP + + +P+ PP ++ P+ P EV ++ +
Sbjct: 608 LSPPPEESPLS--PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP 665
Query: 71 PEQE--CEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKK 128
PE+ ++ P + E P + D ++ L EE
Sbjct: 666 PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL-EESP 724
Query: 129 LLDQQLDQELVKRDE--QLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELP 186
LL + +L R E L + E+ P +E HL + +E L ++ +P
Sbjct: 725 LLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSP-QAEEPHLSPQPEEPCLCAVP 783
Query: 187 EQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELS 246
E+ L Q EG P+ +E L P+ +E L P +E L PQ +E LS
Sbjct: 784 EEP----HLSPQAEGPHLSPQPEELHLS-PQTEEPHLS-PVPEEPCLS-PQPEES--HLS 834
Query: 247 EQQEGQLELSEQQEGQLK-HLEHQ--EGQLEVPEEQMGQ 282
Q E +E L LE + E P E+ GQ
Sbjct: 835 PQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873
Score = 37.0 bits (84), Expect = 0.050
Identities = 85/387 (21%), Positives = 145/387 (37%), Gaps = 39/387 (10%)
Query: 1 MSQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQE 60
MS ++ P S + L+ Q Q +Q L Q +L + +Q
Sbjct: 3881 MSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQL 3940
Query: 61 EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLN 120
++ +Q+ +QQQ++ Q+Q QQQ +Q L Q +T Q
Sbjct: 3941 QQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQ----------MGLLNQSRTLLSPQ-- 3988
Query: 121 KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQE--GHLKHLEQQEGQLKHPEQ 178
Q ++++ L + + ++ G LL ++Q E EG H
Sbjct: 3989 -QQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTH--- 4044
Query: 179 QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQ 238
Q G L + E P G+++ + QL L + Q Q + L LP Q
Sbjct: 4045 QGGPLAIGTTPESMATEP----GEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQ 4100
Query: 239 QEGQLELSEQQEG--QLELSEQQEGQLKHLEHQEGQLEVP-EEQMGQL--KYLEQQEGQL 293
Q+ Q+ L G +L + + H Q V +Q G + L Q+ L
Sbjct: 4101 QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPML 4160
Query: 294 KHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQL 353
+ Q P+ P+ G + L+ +G P G + + + QL+ + + QL
Sbjct: 4161 ERPMQNNTGPQPPKP--GPV--LQSGQGLP-----GVGIMPTVGQLRAQLQGVLAKNPQL 4211
Query: 354 EHLEHQEGQLGLPEQQVLQLKQLEKQQ 380
HL Q+ Q Q +L +QL++ Q
Sbjct: 4212 RHLSPQQQQ---QLQALLMQRQLQQSQ 4235
Score = 36.6 bits (83), Expect = 0.066
Identities = 58/245 (23%), Positives = 94/245 (38%), Gaps = 32/245 (13%)
Query: 1 MSQQHTLPVT--LSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSK 58
+S+ LPV LSP + L PPP + + + L PP + P P E S
Sbjct: 650 VSRLSPLPVVSRLSPPPEESPLS--PPPEESPTSPPPEASRLSPPPEDSPTSPPPE-DSP 706
Query: 59 QEEKHMTAVKGLPEQEC------EQQQKEPQEQ--ELQQQHWEQHEEYQKAE---NPEQQ 107
++ LP +E E+ Q P+ + L + E H + E +P+ +
Sbjct: 707 ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766
Query: 108 LKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLE 167
Q ++ + EE L Q L + E+L + P+ +E HL +
Sbjct: 767 EPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLS-------PQTEEPHLSPVP 819
Query: 168 QQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL----ELPEQQEGQL 223
++ PE+ L Q E P +E L PE ++ L E P ++ GQ
Sbjct: 820 EEPCLSPQPEES----HLSPQSEEPCLSPRPEESHLS-PELEKPPLSPRPEKPPEEPGQC 874
Query: 224 ELPEQ 228
PE+
Sbjct: 875 PAPEE 879
Score = 34.3 bits (77), Expect = 0.33
Identities = 51/200 (25%), Positives = 77/200 (38%), Gaps = 11/200 (5%)
Query: 183 LELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQ 242
LE E + G L LP + ++ E L E +L E ++ +L+ QQ Q
Sbjct: 3210 LEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQ 3269
Query: 243 LELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQ 302
L+ ++QQ+ Q QQ+ L + +P E G L + QL +Q
Sbjct: 3270 LQPAQQQQQQ-----QQQHSLLSAPGPAQAMSLPHE--GSSPSLAGSQQQLSLGLAGARQ 3322
Query: 303 PELPEQQMGQL--KHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE 360
P LP+ M H QQ P + Q L Q G L Q+ L Q+
Sbjct: 3323 PGLPQPLMPTQPPAHALQQRLAPS-MAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLS-QK 3380
Query: 361 GQLGLPEQQVLQLKQLEKQQ 380
+P ++ +QL QQ
Sbjct: 3381 PMGTMPPSMCMKPQQLAMQQ 3400
Score = 32.3 bits (72), Expect = 1.2
Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 12/114 (10%)
Query: 461 KNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQL 520
+ E E L LP L+K E+ L E + LE ++K L+ +Q QL
Sbjct: 3211 EKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQL 3270
Query: 521 KHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQ 574
+ +QQ+ Q +Q APG Q + +LP +G QQQ
Sbjct: 3271 Q----------PAQQQQQQQQQHSLLSAPGPAQAM--SLPHEGSSPSLAGSQQQ 3312
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 92.8 bits (229), Expect = 8e-19
Identities = 121/535 (22%), Positives = 242/535 (45%), Gaps = 43/535 (8%)
Query: 31 QEQMKQPTPLPPPCQKVPVELPVEVPS----KQEEKHMTAVKGLPEQECEQQQKEPQEQE 86
++ ++Q + L ++ +L +EV + K+E + M A L E + +K +
Sbjct: 610 KDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRA--NLEELRSQHNEKVEENST 667
Query: 87 LQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLG 146
LQQ+ E E +K Q+K E+ Q ++ + L+++ + +LD D + G
Sbjct: 668 LQQRLEESEGELRKNLEELFQVKMEREQHQTEI-RDLQDQLSEMHDELDSAKRSEDREKG 726
Query: 147 MKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ----EGQL--ELPEQQEGQLELPEQQE 200
E+LL+ + + L E+QE L+ E++ +G L E+ + +L EQ +
Sbjct: 727 ALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYD 786
Query: 201 GQLE-LPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQ 259
+L+ L E E + E + EQ + E+ + L E+ E SE+
Sbjct: 787 AELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKL-----LQEENEKLQGRSEEL 841
Query: 260 EGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQ-----QEKQPELPEQQMGQLK 314
E ++ L+ Q L+ E + + L++ EG+++ L++ ++++ E +
Sbjct: 842 ERRVAQLQRQIEDLKGDEAKAKET--LKKYEGEIRQLEEALVHARKEEKEAVSARRALEN 899
Query: 315 HLEQQEGQPKHLEQQEGQL-EQLEEQEGQLKHLEQQEGQLE----HLEHQEGQLGLPEQQ 369
LE +G Q++ QL E+L+E+ Q + L + + ++E HL +L
Sbjct: 900 ELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMAD 959
Query: 370 VLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQ 429
+++ + + Q + E +E + L + + QLK E LE ++ ++ ++ Q +
Sbjct: 960 IVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLK-----EKTLEAEKSRLTAMKMQ-DE 1013
Query: 430 LKHLEEQEGQLKHLEQQQGQLEVPEQQVGQP-KNLEQE-EKQLELPEQQEGQVKHLEKQE 487
++ +EE +L+ ++ Q + Q + Q K+LE E E + L + + VK +E +
Sbjct: 1014 MRLMEE---ELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKV 1070
Query: 488 AQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQ 542
+QLE+ ++ L E+ EQ + L Q+ +DLE K LE+
Sbjct: 1071 SQLEMELEEERNNSDL-LSERISRSREQMEQLRNELLQERAARQDLECDKISLER 1124
Score = 78.2 bits (191), Expect = 2e-14
Identities = 120/541 (22%), Positives = 243/541 (44%), Gaps = 81/541 (14%)
Query: 76 EQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLK----QEKTQRDQQLNKQL---EEEKK 128
E++Q + + ++LQ Q E H+E A+ E + K +E Q Q L L EE++
Sbjct: 692 EREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQED 751
Query: 129 LLDQQ----------LDQELVKRDEQLGMKKEQ----LLELPEQQEGHLKHLEQQEGQLK 174
LL ++ L +E+ D+++ KEQ L L E E K++E +
Sbjct: 752 LLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSN 811
Query: 175 HPEQQEGQLELP--------EQQEGQLELPEQQEGQLE-----LPEQQEGQLELPEQQEG 221
EQ + E+ E+ +G+ E E++ QL+ L + E ++ EG
Sbjct: 812 TSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEG 871
Query: 222 QLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQ-LEVPEEQM 280
E+ + +E + ++++ + E +LE ++ Q + Q + L+ EQ
Sbjct: 872 --EIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQK 929
Query: 281 GQLKYLEQQ-EGQLKHLDQ-----QEKQPELPEQQMGQLKHLEQQ-----EGQPKHLEQQ 329
QL+ L+ + E + HL + Q++ ++ E L+ Q E + L +
Sbjct: 930 EQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEM 989
Query: 330 EGQLEQ--LEEQEGQLKHLEQQEG----QLEHLEHQEGQ-LGLPEQQVLQ--LKQLEKQQ 380
+ QL++ LE ++ +L ++ Q+ + E ++Q Q L ++Q+L+ LK LE +
Sbjct: 990 QRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYEL 1049
Query: 381 GQPKHLEEEEGQL-KHLVQQEGQLKHLVQQEG--------QLEQQERQVEHLEQQVGQLK 431
HL+++ +L K + + QL+ +++E ++ + Q+E L ++ Q +
Sbjct: 1050 EAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQER 1109
Query: 432 HLEEQ--------EGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHL 483
+ E Q K L+ + LE + + ++ E + EL ++ E +
Sbjct: 1110 AARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESE---- 1165
Query: 484 EKQEAQLELPEQQVGQP-KHLEQQ--EKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL 540
E+ A L+L +++ + K L Q ++HL +Q+D L+ + Q+++ E++ +L
Sbjct: 1166 ERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRL 1225
Query: 541 E 541
E
Sbjct: 1226 E 1226
Score = 73.9 bits (180), Expect = 4e-13
Identities = 109/457 (23%), Positives = 213/457 (46%), Gaps = 58/457 (12%)
Query: 59 QEEKHMTAVKGLPEQECEQQQK-EPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQ 117
Q ++ + +KG + E +K E + ++L++ +E ++A + + L+ E
Sbjct: 847 QLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQG 906
Query: 118 QLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPE 177
L++ +E+K QL ++L + EQ KEQL L + E HL G+
Sbjct: 907 NLSQTTQEQK-----QLSEKLKEESEQ----KEQLRRLKNEMENERWHL----GKTIEKL 953
Query: 178 QQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQ 237
Q+E + + LEL Q + E E+ +L ++Q + L ++ +
Sbjct: 954 QKEMADIVEASRTSTLELQNQLD---EYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKM 1010
Query: 238 QQEGQL---ELSEQQEGQLE-LSEQQ--EGQLKHLEHQ-EGQLEVPEEQMGQLKYLEQQE 290
Q E +L EL + Q Q E L+++Q E LK LE++ E + + +++ +K +E +
Sbjct: 1011 QDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKV 1070
Query: 291 GQLK-HLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQ 349
QL+ L+++ +L +++ + + EQ E L Q+ + LE + L+ +
Sbjct: 1071 SQLEMELEEERNNSDLLSERISRSR--EQMEQLRNELLQERAARQDLECDKISLERQNKD 1128
Query: 350 -EGQLEHLE--HQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHL 406
+ ++ HLE ++ + GL Q ++ +LE + LE EE +L +L
Sbjct: 1129 LKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR------LESEERDRANLQLSNRRL--- 1179
Query: 407 VQQEGQLEQQERQVEHLEQQVGQLKHLE--EQEGQLK-HLEQQQGQLEVPEQQVGQ---- 459
ER+V+ L QV +HL +Q+ QL L+ + Q+E E+++ +
Sbjct: 1180 ----------ERKVKELVMQVDD-EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESS 1228
Query: 460 PKNLEQE-EKQLELPEQQEGQVKHLEKQEAQLELPEQ 495
K L++E E+Q+++ E +GQ+ ++K +LP +
Sbjct: 1229 KKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSK 1265
Score = 58.2 bits (139), Expect = 2e-08
Identities = 76/365 (20%), Positives = 170/365 (46%), Gaps = 38/365 (10%)
Query: 186 PEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLEL 245
P+ +GQ EL +Q E+ Q+ +EG + + + ++ L ++ L+
Sbjct: 537 PDLLKGQQELTQQTN------EETAKQILYNYLKEGSTDNDDATKRKVNLVFEKIQTLK- 589
Query: 246 SEQQEGQLELSEQ---QEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQ 302
+ G + + Q ++K L Q+ +L + ++ + LE + Q +++ +
Sbjct: 590 -SRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMR 648
Query: 303 PELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQ 362
L E + + +E+ + LE+ EG+L + E+ Q+K +E+++ Q E + Q+
Sbjct: 649 ANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVK-MEREQHQTEIRDLQD-- 705
Query: 363 LGLPEQQVLQLKQLEKQQGQPKHLEEEE--GQLKHLVQQEGQLKHLV----QQEGQLEQQ 416
QL ++ + K E+ E ++ L+Q + L+ L+ +QE L ++
Sbjct: 706 ---------QLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 756
Query: 417 ERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQ-PKNLEQEEKQLELPEQ 475
ER++ L+ + + +QE K EQ +L+ + V + KN+E + EQ
Sbjct: 757 ERELTALKGALKEEVSSHDQEMD-KLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQ 815
Query: 476 Q----EGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKH-LEQQEGQL 530
E +VK L+++ +L+ +++ + + Q ++ +E + + + K L++ EG++
Sbjct: 816 DQAGTEMRVKLLQEENEKLQGRSEEL--ERRVAQLQRQIEDLKGDEAKAKETLKKYEGEI 873
Query: 531 KDLEQ 535
+ LE+
Sbjct: 874 RQLEE 878
Score = 45.4 bits (106), Expect = 1e-04
Identities = 71/297 (23%), Positives = 127/297 (42%), Gaps = 53/297 (17%)
Query: 54 EVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKT 113
E+ + +EK + A K Q + E+EL+ Q E K + EQ LK +
Sbjct: 988 EMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEY 1047
Query: 114 QRD---------QQLNKQLEEEKKLLDQQLDQELVKRD---EQLGMKKEQLLELPEQ--Q 159
+ + +L KQ+E++ L+ +L++E D E++ +EQ+ +L + Q
Sbjct: 1048 ELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQ 1107
Query: 160 EGHLKH--------LEQQEGQLK---------HPEQQEGQLELPEQQ----EGQLELPEQ 198
E + LE+Q LK + +EG + E + E +LE E+
Sbjct: 1108 ERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEER 1167
Query: 199 QEGQLELP----EQQEGQLELPEQQEGQLELPEQQEGQLELP------QQQEGQLELSEQ 248
L+L E++ +L + E L L +Q++ QL L Q +E + E+
Sbjct: 1168 DRANLQLSNRRLERKVKELVMQVDDE-HLSLTDQKD-QLSLRLKAMKRQVEEAEEEIDRL 1225
Query: 249 QEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPEL 305
+ + +L + E Q+ EH +GQL ++ + +LK L K LD + +L
Sbjct: 1226 ESSKKKLQRELEEQMDMNEHLQGQLNSMKKDL-RLKKLPS-----KVLDDMDDDDDL 1276
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 92.4 bits (228), Expect = 1e-18
Identities = 129/558 (23%), Positives = 241/558 (43%), Gaps = 63/558 (11%)
Query: 31 QEQMKQP------TPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKE--P 82
QE+ + P +P PP +V PV P + E + A++ Q EQ Q+
Sbjct: 553 QEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLE 612
Query: 83 QEQELQQQHWEQ--HEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ-------- 132
+QE QQ E+ EE ++ QQ +Q + ++L K +EEE+ + +
Sbjct: 613 SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW 672
Query: 133 ---------QLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQL 183
Q D++ ++ +++ ++K + EL QQ+ LEQ+ Q+ EQ + ++
Sbjct: 673 LRAQVQSSTQADEDQIRAEQEASLQKLR-EELESQQKAERASLEQKNRQML--EQLKEEI 729
Query: 184 ELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLE--------L 235
E E+ E +++ +L EQ EG E++E L ++ +LE
Sbjct: 730 EASEKSEQAALNAAKEKALQQLREQLEG-----ERKEAVATLEKEHSAELERLCSSLEAK 784
Query: 236 PQQQEGQLELSEQQEGQLELSEQQE--GQLKHLEHQEG-QLEVPEEQMGQLKYLEQQEGQ 292
++ L+ Q+ Q E ++ Q+ GQ++H HQ+ + E ++ L ++QE +
Sbjct: 785 HREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVE 844
Query: 293 LKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQ 352
+H + +K E E Q K EQ E E+++ + E L G+L+ L++ +
Sbjct: 845 GEHERRLDKMKE--EHQQVMAKAREQYEA-----EERKQRAELLGHLTGELERLQRAHER 897
Query: 353 LEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLK-HLVQQEGQLKHLVQQEG 411
QE L + + +Q K Q LE +K L E Q + +++
Sbjct: 898 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ 957
Query: 412 QLEQQERQVE-HLEQQVGQLKHLEEQEGQLKHLEQQQGQL-EVPEQQVGQPKNLEQEEKQ 469
QL +RQV E+ + LEE + + HL Q QL E+ ++ + LE +
Sbjct: 958 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL 1017
Query: 470 LELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEG- 528
L+ QQ KH EA+ + + + + + +E + + D ++ L + G
Sbjct: 1018 LQAQSQQ--LQKHFSSLEAEAQKKQHLL---REVTVEENNASPHFEPDLHIEDLRKSLGT 1072
Query: 529 -QLKDLEQQKGQLEQPVF 545
Q K++ Q ++ ++
Sbjct: 1073 NQTKEVSSSLSQSKEDLY 1090
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 92.0 bits (227), Expect = 1e-18
Identities = 123/531 (23%), Positives = 235/531 (44%), Gaps = 42/531 (7%)
Query: 73 QECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ 132
QE E KE + +++++ + E + QL EK Q +QL + E
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETE-------- 894
Query: 133 QLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQ-EG 191
L E + +L KK++L E+ E +E++E + +H + ++ +++ Q+ E
Sbjct: 895 -LCAEAEELRARLTAKKQELEEICHDLEA---RVEEEEERCQHLQAEKKKMQQNIQELEE 950
Query: 192 QLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ-----QEGQLELPQQQEGQLELS 246
QLE E +L+L E+ + +L + +E Q+ L +Q +E +L + E L+
Sbjct: 951 QLEEEESARQKLQL-EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT 1009
Query: 247 EQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQL-KYLEQQEGQLKHLDQQ--EKQP 303
E++E L++ + + E +L E+Q +L K + EG L Q E Q
Sbjct: 1010 EEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA 1069
Query: 304 ELPEQQMGQLKHLEQQEGQPKHLEQQEGQ----LEQLEEQEGQL----KHLEQQEGQLEH 355
++ E +M K E+ + +E++ Q L+++ E E Q+ + LE +
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNK 1129
Query: 356 LEHQEGQLGLPEQQVLQ------LKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQ 409
E Q+ LG E + L+ L QQ E+E LK +++E + H Q
Sbjct: 1130 AEKQKRDLG-EELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAK-THEAQI 1187
Query: 410 EGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKH-LEQQQGQLEVPEQQVGQPKNLEQEEK 468
+ ++ + VE L +Q+ Q K ++ + K LE ++G+L + + Q K + ++
Sbjct: 1188 QEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKR 1247
Query: 469 QLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQL-KHLEQQE 527
+ + QE QVK E + + EL ++ L+ L + + +L K E
Sbjct: 1248 KKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALE 1307
Query: 528 GQLKDLEQ--QKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQ 576
QL+D ++ Q+ ++ + QV+D + + + E +H +KQ
Sbjct: 1308 SQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
Score = 91.3 bits (225), Expect = 2e-18
Identities = 130/553 (23%), Positives = 244/553 (44%), Gaps = 59/553 (10%)
Query: 31 QEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQ 90
QEQ++ T L +++ L + +E H + + E+E Q + +++++QQ
Sbjct: 886 QEQLQAETELCAEAEELRARLTAKKQELEEICHDLEAR-VEEEEERCQHLQAEKKKMQQN 944
Query: 91 HWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQ----------LDQELVK 140
E E+ ++ E+ Q+L+ EK + +L K+LEEE+ +L+ Q L+ + +
Sbjct: 945 IQELEEQLEEEESARQKLQLEKVTTEAKL-KKLEEEQIILEDQNCKLAKEKKLLEDRIAE 1003
Query: 141 RDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQ-EG-QLELPEQ 198
L ++E+ L + + H + E +L+ E+Q +LE ++ EG +L +Q
Sbjct: 1004 FTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQ 1063
Query: 199 -QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQ----LELPQQQEGQL-ELSEQQEGQ 252
E Q ++ E + + E+ + L E++ Q L+ ++ E Q+ EL E E +
Sbjct: 1064 IAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE 1123
Query: 253 LELSEQQEGQLKHLEHQEGQLEVPEEQ-------MGQLKYLEQQEGQL--KHLDQQEKQP 303
+ E Q + L + L+ E +L+ +QE + K L+++ K
Sbjct: 1124 RASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTH 1183
Query: 304 ELPEQQMGQLKHLEQQEGQPKHLEQQ-------EGQLEQLEEQEGQL----KHLEQQEGQ 352
E Q+M Q KH + E + LEQ E + LE + G+L K L Q +G
Sbjct: 1184 EAQIQEMRQ-KHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGD 1242
Query: 353 LEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQ 412
EH + + LQ Q++ +G+ E + K V+ + L Q + +
Sbjct: 1243 SEHKRKK-------VEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295
Query: 413 LEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKN--LEQEEKQL 470
+ + LE Q+ + L ++E +Q+ L +QV KN EQ E++
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEE------NRQKLSLSTKLKQVEDEKNSFREQLEEEE 1349
Query: 471 ELPEQQEGQVKHLEKQEAQLELP-EQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQ 529
E E Q+ L Q A ++ E VG + E+ ++ L+ + +G + E++
Sbjct: 1350 EAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQ--KDLEGLSQRHEEKVAA 1407
Query: 530 LKDLEQQKGQLEQ 542
LE+ K +L+Q
Sbjct: 1408 YDKLEKTKTRLQQ 1420
Score = 88.6 bits (218), Expect = 1e-17
Identities = 129/558 (23%), Positives = 244/558 (43%), Gaps = 59/558 (10%)
Query: 20 LKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQ 79
++ + ++ QE ++ +K +L E+ + + E T L +Q+
Sbjct: 1106 IRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT----LDSTAAQQEL 1161
Query: 80 KEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLD--QQLDQE 137
+ +EQE+ EE + E Q+++Q+ +Q ++L +QLE+ K++ ++ Q
Sbjct: 1162 RSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQT 1221
Query: 138 LVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQ--EGQLKHPEQQEGQLELPEQ-QEGQLE 194
L +L + + LL+ E K +E Q E Q+K E + + EL ++ + Q+E
Sbjct: 1222 LENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVE 1281
Query: 195 LPEQQEGQLELPEQQEGQLE-----LPEQQEGQLELPEQQEGQ-----LELPQQQEGQLE 244
L + G L + + +L L Q + EL +++ Q +L Q ++ +
Sbjct: 1282 L-DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
Query: 245 LSEQQEGQLELSEQQEGQL-----------KHLEHQEGQLEVPEEQMGQLK-----YLEQ 288
EQ E + E E Q+ K +E G LE EE +L+ ++
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 289 QEGQLKHLDQQEKQPELPEQQMGQLK-HLEQQEGQPKHLEQQEGQLEQL--EEQEGQLKH 345
E ++ D+ EK +Q++ L L+ Q +LE+++ + +QL EE+ K+
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKY 1460
Query: 346 LEQQEGQLEHLEHQEGQLGLPEQQVLQL-KQLEKQQGQPKHLEEEEGQLKHLVQQEGQLK 404
E+++ E + E + L L + LE+ Q LE Q + + E +
Sbjct: 1461 AEERD-------RAEAEAREKETKALSLARALEEAMEQKAELERLNKQFR--TEMEDLMS 1511
Query: 405 HLVQQEGQLEQQERQVEHLEQQVGQLK-HLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNL 463
+ + E+ LEQQV ++K LEE E +L+ E + +LEV Q +
Sbjct: 1512 SKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFER 1571
Query: 464 EQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQ----VGQPKHLEQQEKHLE-----HPE 514
+ + + + E+++ V+ + + EA+LE +Q V K LE K LE +
Sbjct: 1572 DLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANK 1631
Query: 515 QQDGQLKHLEQQEGQLKD 532
+D +K L + + Q+KD
Sbjct: 1632 NRDEAIKQLRKLQAQMKD 1649
Score = 82.4 bits (202), Expect = 1e-15
Identities = 111/459 (24%), Positives = 215/459 (46%), Gaps = 60/459 (13%)
Query: 137 ELVKRDEQLGMKKEQLLELPEQQ---EGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQL 193
++ +++E++ K+E+L+++ E+Q E L +E + QL +L+L EQ + +
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQL-----MAEKLQLQEQLQAET 893
Query: 194 EL-PEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ--QEGQLELPQQQEGQLELSEQQE 250
EL E +E + L +++ E+ E ++E E+ Q Q E + Q+ EL EQ E
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 251 GQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQM 310
E S +Q+ QL+ + + ++ EEQ+ LE Q +L K+ +L E ++
Sbjct: 954 E--EESARQKLQLEKVTTEAKLKKLEEEQI----ILEDQNCKL------AKEKKLLEDRI 1001
Query: 311 GQL-KHLEQQEGQPKHLEQQEGQLE-QLEEQEGQLKHLEQQEGQLEHLEHQ-EGQLGLPE 367
+ +L ++E + K L + + + E + + E +L+ E+Q +LE + EG
Sbjct: 1002 AEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLS 1061
Query: 368 QQVLQLK-QLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQ 426
Q+ +L+ Q+ + + Q EEE + L + ++ Q +++ LE Q
Sbjct: 1062 DQIAELQAQIAELKMQLAKKEEE---------LQAALARVEEEAAQKNMALKKIRELESQ 1112
Query: 427 VGQLKH-LEEQEGQLKHLEQQQGQL--EVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHL 483
+ +L+ LE + E+Q+ L E+ + L+ Q EL ++E +V L
Sbjct: 1113 ISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172
Query: 484 EK---QEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL 540
+K +EA+ + Q + KH + E+ E EQ +LE+ + + LE ++G+L
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK---QTLENERGEL 1229
Query: 541 EQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQ 579
+++ L KG+ EH+++K E Q
Sbjct: 1230 -----------ANEVKVLLQGKGD----SEHKRKKVEAQ 1253
Score = 66.6 bits (161), Expect = 6e-11
Identities = 121/548 (22%), Positives = 233/548 (42%), Gaps = 72/548 (13%)
Query: 45 QKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENP 104
++V EL +V Q E + V GL Q + K ++ + + +E + EN
Sbjct: 1265 ERVRTELADKVTKLQVE--LDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENR 1322
Query: 105 EQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLK 164
++ K KQ+E+EK +QL++E +E ++Q+ L Q K
Sbjct: 1323 QKLSLSTKL-------KQVEDEKNSFREQLEEE----EEAKHNLEKQIATLHAQVADMKK 1371
Query: 165 HLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLE 224
+E G L+ E+ + +L+ + EG + E++ + E+ + +L+ E + ++
Sbjct: 1372 KMEDSVGCLETAEEVKRKLQ--KDLEGLSQRHEEKVAAYDKLEKTKTRLQ-QELDDLLVD 1428
Query: 225 LPEQQEG--QLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQ 282
L Q++ LE Q++ QL E+ E+ + + E + L +
Sbjct: 1429 LDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARA---- 1484
Query: 283 LKYLEQQEGQLKHLDQQ--EKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLE-QLEEQ 339
L+ +Q+ +L+ L++Q + +L + K + + E + LEQQ +++ QLEE
Sbjct: 1485 LEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544
Query: 340 EGQLKHLEQQEGQLE-HLEHQEGQL-----GLPEQQVLQLKQLEKQQGQPK-HLEEEEGQ 392
E +L+ E + +LE +L+ + Q G EQ + KQL +Q + + LE+E Q
Sbjct: 1545 EDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQ 1604
Query: 393 LKHLVQQEGQLK--------HLVQQEGQLEQQERQVEHLEQQVGQ--------------- 429
V +L+ H+ ++ +Q+ L+ Q+
Sbjct: 1605 RSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEI 1664
Query: 430 LKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEG----------Q 479
L +E E +LK +E + QL+ + K Q+E+ EL ++ +
Sbjct: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD-ELADEIANSSGKGALALEE 1723
Query: 480 VKHLEKQEAQL--ELPEQQVGQPKHLEQQEKHLEHPEQQDGQL----KHLEQQEGQLKDL 533
+ LE + AQL EL E+Q ++ +K +Q + L H ++ E + L
Sbjct: 1724 KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 1783
Query: 534 EQQKGQLE 541
E+Q +L+
Sbjct: 1784 ERQNKELK 1791
Score = 66.6 bits (161), Expect = 6e-11
Identities = 79/400 (19%), Positives = 188/400 (47%), Gaps = 40/400 (10%)
Query: 80 KEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELV 139
K E E ++ EQ E K + E + ++ Q + +LE + + Q +++L
Sbjct: 1518 KSVHELEKSKRALEQQVEEMKTQLEELE---DELQATEDAKLRLEVNLQAMKAQFERDLQ 1574
Query: 140 KRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQ 199
RDEQ KK+QL+ + E L+ E+++ + +++ +++L + + + +
Sbjct: 1575 GRDEQSEEKKKQLVRQVREMEAELED-ERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633
Query: 200 EGQLELPEQQEGQL-----ELPEQQEGQLE-LPEQQEGQLELPQQQEGQLELSEQQEGQL 253
+ ++ + + Q+ EL + + + E L + +E + +L + ++L E+
Sbjct: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693
Query: 254 ELSEQQEGQLKHLEHQ------EGQLEVPEE-----QMGQL-KYLEQQEGQLKHLDQQEK 301
Q + + L + +G L + E+ ++ QL + LE+++G + ++ + K
Sbjct: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK 1753
Query: 302 QPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLK-HLEQQEGQLEHLEHQE 360
+ L Q+ +LE+ H ++ E +QLE Q +LK L++ EG ++ +
Sbjct: 1754 KANLQIDQINTDLNLER-----SHAQKNENARQQLERQNKELKVKLQEMEGTVK--SKYK 1806
Query: 361 GQLGLPEQQVLQLK-----QLEKQQGQPKHLEEEEGQLKH-LVQQEGQLKHLVQQEGQLE 414
+ E ++ QL+ + +++Q K + E +LK L+Q + + ++ Q + Q +
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQAD 1866
Query: 415 QQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPE 454
+ +++ L++Q+ + E+E Q + +++ Q E+ +
Sbjct: 1867 KASTRLKQLKRQLEE----AEEEAQRANASRRKLQRELED 1902
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 90.1 bits (222), Expect = 5e-18
Identities = 121/526 (23%), Positives = 244/526 (46%), Gaps = 80/526 (15%)
Query: 66 AVKGLPEQECEQQQKEPQ-----EQELQ-QQHWEQHEEYQKAENPEQQLKQEKTQRDQQL 119
A+ LP C QQ+ Q EQE + +Q WEQ+ Y + D
Sbjct: 2 ALPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMS-------------DICS 48
Query: 120 NKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ 179
+KQ E K Q +R++ MK+E+ L ++E L+ L Q+E L E +
Sbjct: 49 SKQAEWSSKT-SYQRSMHAYQREK---MKEEKRRSLEARRE-KLRQLMQEEQDLLARELE 103
Query: 180 EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ---QEGQLELPEQQEGQLELP 236
E +L + Q+ E Q G+L+ ++++ +L + EQ + + P+ +E +L+L
Sbjct: 104 ELRLSMNLQERRIRE----QHGKLKSAKEEQRKL-IAEQLLYEHWKKNNPKLREMELDLH 158
Query: 237 QQQE-GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEG-QLK 294
Q+ E+ ++++ Q E + +QE + E++ + E E + + + ++ Q +
Sbjct: 159 QKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQAE 218
Query: 295 HLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLE 354
L QQ ++ +L E + +LK ++QE +L +Q +LE+LEE+ Q++ Q+
Sbjct: 219 ALLQQMEELKLKEVEATKLK--KEQE----NLLKQRWELERLEEERKQMEAFRQKAELGR 272
Query: 355 HLEHQ-EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQE------GQLKHLV 407
L HQ QL QQ+ + + +++ Q +E+E Q HL ++E +K +
Sbjct: 273 FLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAI 332
Query: 408 QQEGQLEQ------------------QERQVEHLEQQVGQLKHLEE------QEGQLKHL 443
+++ QLE+ ++R+ E ++ + + + E Q+ Q K
Sbjct: 333 EEQLQLERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEVLTGRQQQIQEKIE 392
Query: 444 EQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHL 503
+ ++ Q E + + +NLE+ + +++ ++K KQE + ++ E+++ Q
Sbjct: 393 QNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAERRL-QAWEA 451
Query: 504 EQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAP 549
+QQE E+++ + + +EQ L L+Q+ + + + P P
Sbjct: 452 DQQE------EEEEEEARRVEQLSDAL--LQQEAETMAEQGYRPKP 489
Score = 63.5 bits (153), Expect = 5e-10
Identities = 80/358 (22%), Positives = 169/358 (47%), Gaps = 44/358 (12%)
Query: 61 EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLN 120
+KH+ + ++E +QQ+ ++ EN + + E+ +R+
Sbjct: 159 QKHVVNSWEMQKEEKKQQEATAEQ-----------------ENKRYENEYERARREALER 201
Query: 121 KQLEEEKKLLDQQLDQE-LVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ 179
+ EEE++ L+ +L E L+++ E+L +K+ + +L ++QE LK Q +L+ E++
Sbjct: 202 MKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLK----QRWELERLEEE 257
Query: 180 EGQLELPEQQ-EGQLELPEQQEGQLELPEQQ-EGQLELPEQQEGQLELPEQQEGQLELPQ 237
Q+E Q+ E L Q QL QQ + +LE + L E + +L L +
Sbjct: 258 RKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLAR 317
Query: 238 QQEGQLE---LSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLK 294
+++ + + + E QL+L +E +L+ L +E + E+ E++ + ++ ++ +
Sbjct: 318 REQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAK-EMWEKR--EAEWARERSAR-- 372
Query: 295 HLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLE 354
D+ + QQ Q K + + Q + L+ +E + LEE + +++ +L+
Sbjct: 373 --DRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLK 430
Query: 355 HLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQ 412
QE + + E++ LQ + ++Q+ EEEE + + + Q L+QQE +
Sbjct: 431 SARKQELEAQVAERR-LQAWEADQQE------EEEEEEARRVEQLSDA---LLQQEAE 478
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 90.1 bits (222), Expect = 5e-18
Identities = 121/526 (23%), Positives = 244/526 (46%), Gaps = 80/526 (15%)
Query: 66 AVKGLPEQECEQQQKEPQ-----EQELQ-QQHWEQHEEYQKAENPEQQLKQEKTQRDQQL 119
A+ LP C QQ+ Q EQE + +Q WEQ+ Y + D
Sbjct: 2 ALPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMS-------------DICS 48
Query: 120 NKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ 179
+KQ E K Q +R++ MK+E+ L ++E L+ L Q+E L E +
Sbjct: 49 SKQAEWSSKT-SYQRSMHAYQREK---MKEEKRRSLEARRE-KLRQLMQEEQDLLARELE 103
Query: 180 EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ---QEGQLELPEQQEGQLELP 236
E +L + Q+ E Q G+L+ ++++ +L + EQ + + P+ +E +L+L
Sbjct: 104 ELRLSMNLQERRIRE----QHGKLKSAKEEQRKL-IAEQLLYEHWKKNNPKLREMELDLH 158
Query: 237 QQQE-GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEG-QLK 294
Q+ E+ ++++ Q E + +QE + E++ + E E + + + ++ Q +
Sbjct: 159 QKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQAE 218
Query: 295 HLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLE 354
L QQ ++ +L E + +LK ++QE +L +Q +LE+LEE+ Q++ Q+
Sbjct: 219 ALLQQMEELKLKEVEATKLK--KEQE----NLLKQRWELERLEEERKQMEAFRQKAELGR 272
Query: 355 HLEHQ-EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQE------GQLKHLV 407
L HQ QL QQ+ + + +++ Q +E+E Q HL ++E +K +
Sbjct: 273 FLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAI 332
Query: 408 QQEGQLEQ------------------QERQVEHLEQQVGQLKHLEE------QEGQLKHL 443
+++ QLE+ ++R+ E ++ + + + E Q+ Q K
Sbjct: 333 EEQLQLERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEVLTGRQQQIQEKIE 392
Query: 444 EQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHL 503
+ ++ Q E + + +NLE+ + +++ ++K KQE + ++ E+++ Q
Sbjct: 393 QNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAERRL-QAWEA 451
Query: 504 EQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAP 549
+QQE E+++ + + +EQ L L+Q+ + + + P P
Sbjct: 452 DQQE------EEEEEEARRVEQLSDAL--LQQEAETMAEQGYRPKP 489
Score = 63.5 bits (153), Expect = 5e-10
Identities = 80/358 (22%), Positives = 169/358 (47%), Gaps = 44/358 (12%)
Query: 61 EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLN 120
+KH+ + ++E +QQ+ ++ EN + + E+ +R+
Sbjct: 159 QKHVVNSWEMQKEEKKQQEATAEQ-----------------ENKRYENEYERARREALER 201
Query: 121 KQLEEEKKLLDQQLDQE-LVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ 179
+ EEE++ L+ +L E L+++ E+L +K+ + +L ++QE LK Q +L+ E++
Sbjct: 202 MKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLK----QRWELERLEEE 257
Query: 180 EGQLELPEQQ-EGQLELPEQQEGQLELPEQQ-EGQLELPEQQEGQLELPEQQEGQLELPQ 237
Q+E Q+ E L Q QL QQ + +LE + L E + +L L +
Sbjct: 258 RKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLAR 317
Query: 238 QQEGQLE---LSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLK 294
+++ + + + E QL+L +E +L+ L +E + E+ E++ + ++ ++ +
Sbjct: 318 REQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAK-EMWEKR--EAEWARERSAR-- 372
Query: 295 HLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLE 354
D+ + QQ Q K + + Q + L+ +E + LEE + +++ +L+
Sbjct: 373 --DRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEKLK 430
Query: 355 HLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQ 412
QE + + E++ LQ + ++Q+ EEEE + + + Q L+QQE +
Sbjct: 431 SARKQELEAQVAERR-LQAWEADQQE------EEEEEEARRVEQLSDA---LLQQEAE 478
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 89.7 bits (221), Expect = 7e-18
Identities = 123/529 (23%), Positives = 226/529 (42%), Gaps = 74/529 (13%)
Query: 76 EQQQKEPQEQELQQQHWEQHEEYQKA-----------ENPEQQLKQEKTQRDQQL----- 119
+ Q + Q +EL++QH + EE++K + QL+QEK Q +L
Sbjct: 117 QHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVY 176
Query: 120 -----NKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEG--- 171
N+QL + + + QL Q++ ++ + L + EQL+ E + L + Q
Sbjct: 177 NLREENRQLRKAHQDIHTQL-QDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYK 235
Query: 172 QLKHPEQQEGQLELPEQQEGQ-----LELPEQQEGQLELP--EQQEGQLELPEQQEGQLE 224
QLK + L P+ E Q P+ E P E QE Q +
Sbjct: 236 QLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAV 295
Query: 225 LPEQQEGQLELPQQQEGQLEL-SEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQL 283
++ +L P +E + + E + ++E E +E Q++ EH++ E EQ+GQ
Sbjct: 296 PGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEE-EHRKALEEEEMEQVGQA 354
Query: 284 KYLEQQ-----EGQLKHLDQQEKQPELPEQQMGQLK---------HLEQQEGQPKHLEQQ 329
++LE++ E Q + +Q +Q E G + ++ Q + LEQQ
Sbjct: 355 EHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQ 414
Query: 330 EGQLEQLEEQEGQLKH---LEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHL 386
++Q+EE + +H L QQ Q L QE Q +++ +Q E ++G+P+H
Sbjct: 415 RLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQ 474
Query: 387 EEEEGQ-----LKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLK 441
E+ Q + + + Q + + + +EG E+ + + E G EQ +
Sbjct: 475 EQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREA 534
Query: 442 HLEQQQGQLEVPE-QQVGQPKNLEQEE-------KQLELPEQQEGQVKHLEKQE-AQLEL 492
E + + V + P N ++E ++ LP++ E Q + +KQE ++E
Sbjct: 535 DPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEE 594
Query: 493 PEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLE 541
G P +QQE +++ Q++ ++E Q E++K +LE
Sbjct: 595 HLVMAGNP---DQQEDNVDEQYQEEA------EEEVQEDLTEEKKRELE 634
Score = 82.0 bits (201), Expect = 1e-15
Identities = 113/498 (22%), Positives = 221/498 (44%), Gaps = 52/498 (10%)
Query: 79 QKEPQEQELQQQHWEQHEEYQKAENP---EQQLKQEKTQRDQQLNKQLEEEKKLLDQQLD 135
Q + ++ E ++QH+E A+ E + + EK+ + ++L + +E L+ +
Sbjct: 37 QTQLRKAEAVALKYQQHQESLSAQLQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEA 96
Query: 136 QELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQ-LE 194
QE + + Q + L + Q L+ Q +LK +Q LE +++G+
Sbjct: 97 QETLNKGRQDSNSRYSALNVQHQM------LKSQHEELK---KQHSDLEEEHRKQGEDFS 147
Query: 195 LPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLE 254
Q L QQE + EL + +E L E+ + Q QL+ +QQ L
Sbjct: 148 RTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVKQQHKNL- 206
Query: 255 LSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQ-MGQL 313
LSE ++ + LE + L + Q+ + K L+ ++ L ++P+ EQQ + Q+
Sbjct: 207 LSEHEQ-LVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSL----RKPDPAEQQNVTQV 261
Query: 314 KHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLE-----HQEGQLGLPE- 367
H Q G E+ +++++ ++ E G+ E + H+E + P
Sbjct: 262 AHSPQ--GYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPE 319
Query: 368 --QQVLQLKQLEKQQGQPKH---LEEEE----GQLKHLVQQEGQLKHLVQQEGQLEQQER 418
QQ ++ ++ E+ Q + +H LEEEE GQ +HL ++ +E + + ++R
Sbjct: 320 PIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQR 379
Query: 419 QVEHLEQQVGQLKHLEEQEGQLK-------HLEQQQ---GQLEVPEQQVGQPKNLEQEEK 468
+ +L + + + + +K LEQQ+ Q+E +Q + L Q+
Sbjct: 380 EAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRL 439
Query: 469 QLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQ--QEKH---LEHPEQQDGQLKHL 523
Q L QQE Q + + ++ A E + G+P+H EQ Q+ H +++ Q + + +
Sbjct: 440 QGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGI 499
Query: 524 EQQEGQLKDLEQQKGQLE 541
+ +EG + Q + + E
Sbjct: 500 QGEEGAYERDNQHQDEAE 517
Score = 73.6 bits (179), Expect = 5e-13
Identities = 94/400 (23%), Positives = 177/400 (44%), Gaps = 53/400 (13%)
Query: 26 PVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAV---KGLPEQECEQ----- 77
P ++ PT Q P + EV ++ E+H K L E+E EQ
Sbjct: 296 PGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAE 355
Query: 78 ---QQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNK-QLEEEKKLLDQQ 133
++ +P +E ++ EQHE+ + A E + E + + K Q E++L Q+
Sbjct: 356 HLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQR 415
Query: 134 LDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQL 193
L + V+ +QL +E L + ++ +GHL L QQE Q QQ+ E+ Q++ +L
Sbjct: 416 LAVQQVEEAQQLREHQEALHQ--QRLQGHL--LRQQEQQ-----QQQVAREMALQRQAEL 466
Query: 194 ELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ-----EGQLELPQQQEGQLE---- 244
E EG+ + EQ Q ++ E Q EG E Q + + E
Sbjct: 467 E-----EGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPG 521
Query: 245 --LSEQQEGQLELSEQQEGQLKHLE--------HQEGQLEVPEEQMGQLKYLEQQEGQLK 294
+++G E + E +E + +G+ E E + + + L + + K
Sbjct: 522 NRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQK 581
Query: 295 HLDQQEKQPELPEQQMGQLKHLEQQEG----QPKHLEQQEGQLEQLEEQEGQLKHLEQQE 350
+Q+++ E+ E+ + + +QQE Q + ++E Q + EE++ +L+H +E
Sbjct: 582 QSNQKQENTEV-EEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEH-NAEE 639
Query: 351 GQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEE 390
E+ E+ + + E+Q +++ + +G+ +H EEEE
Sbjct: 640 TYGENDENTDDKNNDGEEQ--EVRDDNRPKGREEHYEEEE 677
Score = 73.2 bits (178), Expect = 6e-13
Identities = 109/451 (24%), Positives = 191/451 (42%), Gaps = 78/451 (17%)
Query: 55 VPSKQEEKHMTAVKGLPEQECE-QQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKT 113
VP + E+ + A +E E Q EP +QE++++ + EE+Q E + L++E+
Sbjct: 295 VPGRAEDTKLYAPT---HKEAEFQAPPEPIQQEVERR---EPEEHQVEEEHRKALEEEEM 348
Query: 114 QRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQL 173
++ Q + LEEE ++ D+E ++ EQ + LLE + E + + Q
Sbjct: 349 EQVGQA-EHLEEEHDPSPEEQDREWKEQHEQ--REAANLLEGHARAEVYPSAKPMIKFQS 405
Query: 174 KHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL 233
+ EQ E Q +Q E +L E QE QQ Q L QQE Q QQ+
Sbjct: 406 PYEEQLEQQRLAVQQVEEAQQLREHQEAL----HQQRLQGHLLRQQEQQ-----QQQVAR 456
Query: 234 ELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQL 293
E+ Q++ +LE Q ++Q Q H + + + E G ++ +EG
Sbjct: 457 EMALQRQAELEEGRPQH------QEQLRQQAHYDAMDNDIVQGAEDQG----IQGEEGAY 506
Query: 294 KHLDQQEKQPELPEQQMGQLKHLEQQEGQP--KHLEQQEGQLEQLEEQEGQLKHLE---- 347
+ +Q H ++ EG P +H +++G E E E +E
Sbjct: 507 ERDNQ----------------HQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINP 550
Query: 348 ------QQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEG 401
Q E + E E Q + LP++ Q + +KQ+ +EE + QQE
Sbjct: 551 ADDPNNQGEDEFEEAE-QVREENLPDENEEQKQSNQKQEN--TEVEEHLVMAGNPDQQED 607
Query: 402 QLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKH-LEQQQGQLEVPEQQVGQP 460
+ Q+E + E QE EE++ +L+H E+ G+ +
Sbjct: 608 NVDEQYQEEAEEEVQEDLT-------------EEKKRELEHNAEETYGE----NDENTDD 650
Query: 461 KNLEQEEKQLELPEQQEGQVKHLEKQEAQLE 491
KN + EE+++ + +G+ +H E++E + E
Sbjct: 651 KNNDGEEQEVRDDNRPKGREEHYEEEEEEEE 681
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/183 (22%), Positives = 84/183 (45%), Gaps = 19/183 (10%)
Query: 26 PVNTHQEQMKQPTPLPPPCQ--KVPVE--LPVEVPSKQEEKHMTAVKGLPEQECEQQQKE 81
P N H+ + + P P + + VE P + P+ Q E + + E+ + +E
Sbjct: 520 PGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEE 579
Query: 82 PQEQELQQQHWEQHEEYQKAENPEQQL----KQEKTQRDQQLNKQLEEEKKL-LDQQLDQ 136
++ +Q++ E E A NP+QQ +Q + + ++++ + L EEKK L+ ++
Sbjct: 580 QKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEE 639
Query: 137 ELVKRDEQLGMK----KEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQ 192
+ DE K +EQ + + +G +H E++E E++E + E+ +
Sbjct: 640 TYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEE------EEEEDGAAVAEKSHRR 693
Query: 193 LEL 195
E+
Sbjct: 694 AEM 696
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 89.7 bits (221), Expect = 7e-18
Identities = 124/516 (24%), Positives = 231/516 (44%), Gaps = 72/516 (13%)
Query: 80 KEPQEQELQQQHWEQHEEYQKAENP--EQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQE 137
K Q + LQQ+ ++ QK + +Q++ E +RD QL E K ++LD E
Sbjct: 820 KSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSE 879
Query: 138 LVKRDEQL----GMKKE---QLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLEL----- 185
L + ++L G K+ +L L + +H+ EG L+ +++ ++E
Sbjct: 880 LKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSL 939
Query: 186 ---PEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL-----PEQQEGQLELPQ 237
EQ E E + Q+E QQE + + EQ++ L Q+E + +
Sbjct: 940 QFDKEQMVAVTEANEALKKQIE-ELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKA 998
Query: 238 QQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLD 297
+ LS + + L E + +L L Q G + + + ++ E +L+ +
Sbjct: 999 YENAVGILSRRLQEALAAKEAADAELGQLRAQGGS---SDSSLALHERIQALEAELQAVS 1055
Query: 298 QQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEG---QLKHLEQQEGQLE 354
+ E Q++ L E +E + K LE + ++L+E G ++K LE+ +L
Sbjct: 1056 HSKTLLEKELQEVIALTSQELEESREKVLELE----DELQESRGFRKKIKRLEESNKKLA 1111
Query: 355 -HLEHQEGQL--------GLPEQQVLQLKQLEKQQGQPKHLE-EEEGQLKHLVQQEGQLK 404
LEH++G+L L E + L K++ L + + L+ +++ Q+K
Sbjct: 1112 LELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMK 1171
Query: 405 HLVQQ-EGQLEQQERQVEHLEQQVGQLK---------------HLEEQEGQLKHLEQ--Q 446
HLVQ + LE+++ +V L++QV K L E + +L+ E Q
Sbjct: 1172 HLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQ 1231
Query: 447 QGQLEVPEQQVGQPKNLEQ-EEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQ 505
+ Q E + Q+ + K+ ++ + Q EL E + Q++ L+KQ L EQ QP ++
Sbjct: 1232 KLQAEADDLQIREGKHSQEIAQFQAELAEAR-AQLQLLQKQ-----LDEQLSKQPVGNQE 1285
Query: 506 QEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLE 541
E +Q++ +++ L+QQ DL +Q+G+ E
Sbjct: 1286 MENLKWEVDQKEREIQSLKQQ----LDLTEQQGRKE 1317
Score = 72.4 bits (176), Expect = 1e-12
Identities = 117/541 (21%), Positives = 233/541 (43%), Gaps = 61/541 (11%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQ 117
+QE + K E E + +E + E H + + E E + + Q D+
Sbjct: 884 RQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDK 943
Query: 118 QLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPE 177
+ + E + L +Q+++ + + + +K+++ L G Q+E + KH
Sbjct: 944 EQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRL-----GSDLTSAQKEMKTKHKA 998
Query: 178 QQEGQLELPEQQEGQLELPEQQEGQLELPEQQEG----QLELPEQ---QEGQLELPEQQE 230
+ L + + L E + +L Q G L L E+ E +L+ +
Sbjct: 999 YENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSK 1058
Query: 231 GQLELPQQQEGQL---ELSEQQEGQLELSEQ-QEG-----QLKHLEHQEGQLEVP-EEQM 280
LE Q+ L EL E +E LEL ++ QE ++K LE +L + E +
Sbjct: 1059 TLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEK 1118
Query: 281 GQLKYLEQQEGQLKH---------LDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQ-E 330
G+L L Q L+ ++ +L Q L+ E+++ Q KHL Q +
Sbjct: 1119 GKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQ 1178
Query: 331 GQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEE- 389
LE+ +E+ LK EQ H + L+L +++K+ +HL ++
Sbjct: 1179 ASLEKEKEKVNSLK--EQVAAAKVEAGHNRRHF---KAASLELSEVKKELQAKEHLVQKL 1233
Query: 390 EGQLKHLVQQEGQ-LKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQG 448
+ + L +EG+ + + Q + +L + Q++ L++Q+ + L +Q + +E +
Sbjct: 1234 QAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDE--QLSKQPVGNQEMENLKW 1291
Query: 449 QLEVPEQQVGQPKNLEQEEKQLELPEQQ-----EGQVKHLEKQEAQLELPEQQVGQPKHL 503
+++ E+++ + ++QL+L EQQ EG + L+ +++LE+ ++ + +
Sbjct: 1292 EVDQKEREI------QSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLS----M 1341
Query: 504 EQQEKHLEHPEQQD--GQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPT 561
Q++K + + + +K L QQ QLK L+ ++G + G+ PA P
Sbjct: 1342 TQKDKFMLQAKVSELKNNMKTLLQQNQQLK-LDLRRGAAK--TRKEPKGEASSSNPATPI 1398
Query: 562 K 562
K
Sbjct: 1399 K 1399
Score = 61.2 bits (147), Expect = 2e-09
Identities = 122/564 (21%), Positives = 225/564 (39%), Gaps = 71/564 (12%)
Query: 36 QPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPE-QECEQQQKEPQEQELQQQHWEQ 94
Q TP Q++P + + PS ++ A + + QE + + ++ E
Sbjct: 339 QDTPYMVNGQEIPADTLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVSLES 398
Query: 95 HEEYQKAENPEQQLK--QEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQL 152
AE E+ L+ +EK + + QL E + L ++ EL + L K +
Sbjct: 399 ----SAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKA--ELQAQLAALSTKLQAQ 452
Query: 153 LELPEQQEGHLKHLEQQEGQLKHP--EQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE 210
+E + L + LK + + +L E + L++ E+Q
Sbjct: 453 VECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQY 512
Query: 211 GQLELPEQQEGQLELPEQQEGQLELPQQ--------QEGQLE----LSEQQEGQLELSE- 257
+L + + ++ Q + + +L QQ Q+ QLE S+ + Q E+S
Sbjct: 513 QRL-MAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSL 571
Query: 258 -------QQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHL--DQQEKQPELPEQ 308
QQ+ L Q E+ Q+GQ+ Q G L+HL + +L E
Sbjct: 572 QSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMT----QAGLLEHLKLENVSLSQQLTET 627
Query: 309 QMGQLKH----LEQQEGQPKHLEQQEGQLEQLEE-----QEGQLKHLEQQEGQLEHLEHQ 359
Q +K Q +G + QE Q++E +E + LE+ EG+ E L+
Sbjct: 628 QHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRM 687
Query: 360 EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQ 419
EQQ+ Q+K Q+ Q ++E L + Q + L +E L+ +
Sbjct: 688 ADSAASLEQQLEQVKLTLLQRDQQLEALQQE-HLDLMKQLTLTQEALQSREQSLDALQTH 746
Query: 420 VEHLEQQVGQLK-HLEEQEGQLKHLEQQQGQLEVPEQ----------------QVGQPKN 462
+ L+ ++G+L+ +E + L+ ++ LE Q + G +
Sbjct: 747 YDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEET 806
Query: 463 LEQEEKQLELPEQQEGQVKHLEKQEAQL-----ELPEQQVGQPKHLEQQEKHLEHPEQQD 517
E EK E + GQV+HL+++ A L ++ EQ + Q +E + +Q
Sbjct: 807 SETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLI 866
Query: 518 GQLKHLEQQ-EGQLKDLEQQKGQL 540
+LK ++ + +LK+L Q+ Q+
Sbjct: 867 SELKATRKRLDSELKELRQELMQV 890
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 89.0 bits (219), Expect = 1e-17
Identities = 119/544 (21%), Positives = 248/544 (45%), Gaps = 82/544 (15%)
Query: 105 EQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQL------------ 152
E++L QEK ++ K E EKKL+ Q++ L K+ E+L +K +L
Sbjct: 1892 EEKLTQEKETVIKKKEKLAETEKKLV--QVEDSLAKKQEKLAQEKMKLALEKAMVQGKKR 1949
Query: 153 ----LELPEQQEG---HLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLEL 205
L++ ++++ +K L +++ +L ++ + E PE Q ++ + ++ E
Sbjct: 1950 LRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSR-QRKMTQVEQELFER 2008
Query: 206 PEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQ----EGQLELSEQQEGQLELSEQQEG 261
E ++ L E + +E E +G+LE + Q +GQ +L++ ++ E
Sbjct: 2009 KLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSK 2068
Query: 262 Q----------LKHLEHQEGQLEVPEEQMGQLKY----------LEQQEGQLKHLDQQEK 301
+ L+ L E +L E +M ++K +EQ + +K D EK
Sbjct: 2069 EPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEK 2128
Query: 302 QPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQL--KHLE-----QQEGQLE 354
+ EL + + K +Q + + + E++ E+E +L KH E ++EG +E
Sbjct: 2129 RSELTKDEK---KLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185
Query: 355 HLE-----------HQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQL 403
E +E + G ++ Q+++ + + EE E L L +QE
Sbjct: 2186 EEEVIPFLKRRWRKRKEAKRGDKPKEKFS-SQVDEVESEEHFSEEMESLLDELEKQESLS 2244
Query: 404 KHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNL 463
++E + E++ER+ E + ++ + K EE+EG+ K +E+++ + + +++ + +
Sbjct: 2245 SE--EEEEREEEEEREEEEVREEEEERK--EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQ 2300
Query: 464 EQEE----KQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQ 519
E+EE K+ + E++ + E++E L E++V + K + ++EK + EQ+
Sbjct: 2301 EKEEVFEEKEEIMSEEETESLSDEEEEEESCSL-EEEVDREKEILKKEKQFKLQEQRRKS 2359
Query: 520 LKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQ 579
L+ E+ L+ + KG+ + +P + + + AL K + +PV +Q +
Sbjct: 2360 LRGRERVLSILRGVPHGKGRAIRLGVLKSPLK-KLMSTALEMKEKTPVPVPEKQ----IS 2414
Query: 580 WPPK 583
W K
Sbjct: 2415 WEDK 2418
Score = 80.5 bits (197), Expect = 4e-15
Identities = 112/500 (22%), Positives = 235/500 (47%), Gaps = 40/500 (8%)
Query: 58 KQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQ 117
K EE L + EQQ K+ +E L+++ + EE ++ EQ+ QE+ + +
Sbjct: 1517 KWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWAR 1576
Query: 118 QLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPE 177
K+ EKK Q +++L + +E+L ++ QL + + + Q + ++ E
Sbjct: 1577 IHRKRARAEKK--RAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAE 1634
Query: 178 QQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL-ELP 236
+ Q E Q G+ +L ++ E + ++ + E ++E +L ++ G+L E+
Sbjct: 1635 GKFAQKEETLAQRGE-KLSQEAEKLAQKRKKLAKKWEKVAREEEKL---AKKGGKLAEVK 1690
Query: 237 QQQEGQLELSEQQEGQLELSEQQEGQ-LKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKH 295
++E Q+E L+ E++ Q L+ LE +L EE+ L Q+EG+L
Sbjct: 1691 NILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEE------LNQEEGKL-- 1742
Query: 296 LDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEH 355
+++++K E E Q + L ++E + L Q+E L Q +E+ Q K E
Sbjct: 1743 VEEKKKLAEEEEALAWQREKLSEEETK---LAQEEELLIQEKEKLAQHK---------EK 1790
Query: 356 LEHQEGQLGLPEQQVLQ--LKQLEKQQGQPKHLEEEEGQLKHLVQQEG---QLKHLVQQE 410
+ +E +LG +Q+++ +K +K++ +EE L Q++ + K+L Q++
Sbjct: 1791 MPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEK 1850
Query: 411 GQLEQQERQV----EHLEQQVGQLKHLEEQEGQL-KHLEQQQGQLEVPEQQVGQPKN--L 463
+L Q++ + E L QL ++ + G K L Q + +L ++ V + K
Sbjct: 1851 EKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLA 1910
Query: 464 EQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHL 523
E E+K +++ + + + L +++ +L L + V K L + + + + ++K L
Sbjct: 1911 ETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRL 1970
Query: 524 EQQEGQLKDLEQQKGQLEQP 543
+++ +L + ++ + E P
Sbjct: 1971 AEEKMRLVEGKETLSKGETP 1990
Score = 80.5 bits (197), Expect = 4e-15
Identities = 124/523 (23%), Positives = 262/523 (50%), Gaps = 61/523 (11%)
Query: 59 QEEKHMTAVKGLPEQECEQQQKEPQEQ-ELQQQH-WEQ-HEEYQKAENPEQQLKQEKTQR 115
++E+ +T + + + E++Q+ +EQ +Q++H W + H + +AE Q +++ Q
Sbjct: 1539 KDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE 1598
Query: 116 DQQL---NKQLEEEKKLLDQ------QLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHL 166
+++L +QL +E++ L Q Q D+E+ + + + K+E L + E+ + L
Sbjct: 1599 EEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKL 1658
Query: 167 EQQEGQL-KHPEQQEGQLELPEQQEGQL-ELPEQQEGQLELPEQQEGQLELPEQQEGQLE 224
Q+ +L K E+ + E ++ G+L E+ ++E Q+E L+ E++ Q E
Sbjct: 1659 AQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQ-E 1717
Query: 225 LPEQQEGQLELPQQQEGQLELSEQQEGQL-----ELSEQQEG---QLKHLEHQEGQLEVP 276
L E + EL ++E EL+ Q+EG+L +L+E++E Q + L +E +L
Sbjct: 1718 LEELEWDMEELSWKEE---ELN-QEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQE 1773
Query: 277 EEQMGQLK-YLEQQEGQLKHLDQQ--EKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQL 333
EE + Q K L Q + ++ +++ K+ +L E++M + E+ + L + + L
Sbjct: 1774 EELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMIL 1833
Query: 334 EQLEEQEGQLKHLEQQEGQL----EHLEHQEGQLGLPEQQVLQLK----QLEK--QQGQP 383
Q + + K+L Q++ +L E+L + + +L ++Q++Q+K K Q +
Sbjct: 1834 YQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEE 1893
Query: 384 KHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHL 443
K +E+E +K + K LVQ E L +++ ++ + ++ K + + + +L+
Sbjct: 1894 KLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR-- 1951
Query: 444 EQQQGQLEVPEQQVGQPKNLEQE---EKQLELPEQQE----GQVKHLEKQEAQLELPEQQ 496
G+L++ +++ + NLE + E+++ L E +E G+ +Q ++ EQ+
Sbjct: 1952 ----GELDIAKEE--KALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQV-EQE 2004
Query: 497 VGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQ 539
+ + K L +EK L H + ++ +E+ E LE +GQ
Sbjct: 2005 LFERK-LSLEEKILLH----EDRILAMEESEIAKGKLEFTRGQ 2042
Score = 77.0 bits (188), Expect = 4e-14
Identities = 123/575 (21%), Positives = 260/575 (45%), Gaps = 64/575 (11%)
Query: 14 ALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELP-VEVPSKQEEKHMTAVKGLPE 72
A+ +++++ V V H+E M + + + L +V K+ +K + G
Sbjct: 1323 AIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVT 1382
Query: 73 QECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEE----EKK 128
E +KE E++ Q+ +Q + + E ++K+E T+ ++ +++++EE E+K
Sbjct: 1383 MGKEISKKE--EKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEK 1440
Query: 129 LLDQQLDQELVKR-----------DEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPE 177
++ Q+ +++R DE + E +E K L Q+E +L
Sbjct: 1441 VVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAG 1500
Query: 178 QQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQ 237
++ E Q++ +L+ E ++ + + + + +++E LE +EG+ + Q
Sbjct: 1501 EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQ 1560
Query: 238 QQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQ-LKYLEQQEGQLKH- 295
E Q + E+ + ++ + K + +E +L EE++ Q + L Q+E +L
Sbjct: 1561 VTEEQRHIQEEHKWARIHRKRARAEKKRAQ-EERKLAQEEEKLAQEERQLAQEERKLAQA 1619
Query: 296 ---LDQQEKQPELPEQQMGQLKHLEQQEGQ----------------PKHLEQQEGQLEQL 336
+ Q +++ E + Q + Q G+ K E+ + E+L
Sbjct: 1620 YVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKL 1679
Query: 337 EEQEGQLKHLEQQEGQ-LEHLEHQEGQLGLPEQQVLQ-LKQLEKQQGQPKHLEEEEGQLK 394
++ G+L ++ Q +E L +E L E+++ Q L++LE + EEE
Sbjct: 1680 AKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEE----- 1734
Query: 395 HLVQQEGQL----KHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQL 450
L Q+EG+L K L ++E L Q ++ E ++ Q + L QE + L Q + ++
Sbjct: 1735 -LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKE--KLAQHKEKM 1791
Query: 451 EVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHL 510
E+++G+ K + EK+++L +++E + +E +L + + Q K+L Q++K+L
Sbjct: 1792 PEEEERLGR-KREQLIEKKMKLAQKRERWINSME----ELTKNKMILYQKKNLAQEKKNL 1846
Query: 511 EHPEQQDGQLK-----HLEQQEGQLKDLEQQKGQL 540
+++ Q K + E+ K L Q K +L
Sbjct: 1847 AQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKL 1881
Score = 67.0 bits (162), Expect = 5e-11
Identities = 112/544 (20%), Positives = 244/544 (44%), Gaps = 76/544 (13%)
Query: 49 VELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQL 108
++L +E Q +K + + ++E + + E + + E E K E PE
Sbjct: 1935 MKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSR 1994
Query: 109 KQEKTQRDQQL--NKQLEEEKKLLDQ--------------------------QLDQELVK 140
+++ TQ +Q+L K EEK LL + Q ++L K
Sbjct: 1995 QRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAK 2054
Query: 141 RDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQ-----------Q 189
+L K+E L + P + LK L++ + Q+E ++ ++ +
Sbjct: 2055 ASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIE 2114
Query: 190 EGQLELPE----QQEGQLELPEQQ--EGQLELPEQQEGQLELPEQQEGQLELPQQQEGQL 243
+ +L++ E ++ +L E++ Q +L + + E+ + ++ ++
Sbjct: 2115 QSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEV 2174
Query: 244 ELSEQQEGQLELSE----QQEGQLKHLEHQEGQLEVPEEQM-GQLKYLEQQEGQLKH--- 295
L +++EG +E E + K E + G + P+E+ Q+ +E +E +
Sbjct: 2175 ILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRG--DKPKEKFSSQVDEVESEEHFSEEMES 2232
Query: 296 -LDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLE 354
LD+ EKQ L ++ + + E++E + E +E + E+ EE+EG+ K +E++E + +
Sbjct: 2233 LLDELEKQESLSSEEEEEREEEEEREEE----EVREEEEERKEEEEGEEKQVEKEEEEKK 2288
Query: 355 HLEHQEGQLGLPE-QQVLQLKQ--LEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEG 411
+ ++ + + E ++V + K+ + +++ + EEEE + L ++ + K ++++E
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Query: 412 QLEQQERQVEHL---EQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEK 468
Q + QE++ + L E+ + L+ + +G+ L G L+ P +++ +E+
Sbjct: 2349 QFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRL----GVLKSPLKKLMSTALEMKEKT 2404
Query: 469 QLELPEQQEGQVKHLEKQEAQLELPEQQVG-QPKHLEQQEKHLEHPEQQDGQLKHLEQQE 527
+ +PE+ Q+ +K+ +E+P + +G K E K+ P G + LE Q
Sbjct: 2405 PVPVPEK---QISWEDKKATVVEIPRKFLGTMDKEREVMGKYEPIPPHVLGTV--LESQA 2459
Query: 528 GQLK 531
LK
Sbjct: 2460 QDLK 2463
Score = 64.3 bits (155), Expect = 3e-10
Identities = 108/520 (20%), Positives = 243/520 (46%), Gaps = 62/520 (11%)
Query: 117 QQLNKQLEEEKKLLDQQLDQELVKRDE-----QLGMKKEQLLELPEQQEGHLKHL---EQ 168
Q++ L++E K+L + LD ++V ++ Q G +E +++ Q+ K + E+
Sbjct: 1288 QEICPLLKKESKVLLEDLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREE 1347
Query: 169 QEGQLKHPEQ---QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL 225
++ Q K + +E Q+ L + ++ P E+ +++E + ++G+ +
Sbjct: 1348 EQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAV 1407
Query: 226 PEQQE-GQLELPQQQEGQLELSEQQEGQLELSEQ---QEGQLKHLEH-----------QE 270
++++ G+++ +E + ++SE+ E L E+ QEG+L +E E
Sbjct: 1408 QKERKVGKIKREMTKE-ERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDE 1466
Query: 271 GQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPEL-----PEQQMGQ----LKHLEQQEG 321
+ E + + E+ E +L L ++EK + PE++M Q LK E ++
Sbjct: 1467 WKQVHGETRKSWKAWKEEWEKRL--LQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQV 1524
Query: 322 QPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQG 381
L + + + +E+E L+ +EG+ + + E Q + E+ ++ +
Sbjct: 1525 WENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARA 1584
Query: 382 QPKHLEEEEGQLKHLVQQEGQL----KHLVQQEGQL-------EQQERQVEHLEQQVGQL 430
+ K +EE + L Q+E +L + L Q+E +L Q +R++ E + Q
Sbjct: 1585 EKKRAQEE----RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQK 1640
Query: 431 KHLEEQEGQLKHLEQQQGQLEVPEQQVGQP-KNLEQEEKQLELPEQQEGQVKHLEKQEAQ 489
+ Q G+ L Q+ +L +++ + + + +EE++L + +VK++ Q+ +
Sbjct: 1641 EETLAQRGE--KLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVE 1698
Query: 490 LELPEQQVG---QPKHLEQQEKHLE-HPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVF 545
ELP+++ Q K L Q+ + LE E+ + + L Q+EG+L + E++K E+
Sbjct: 1699 -ELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVE-EKKKLAEEEEAL 1756
Query: 546 APAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKHK 585
A ++ + + L + E+L+ + + + + + P + +
Sbjct: 1757 AWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEE 1796
Score = 63.2 bits (152), Expect = 7e-10
Identities = 125/657 (19%), Positives = 280/657 (42%), Gaps = 135/657 (20%)
Query: 54 EVPSKQEEK------HMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQ 107
E +++EEK + VK + Q+ E+ + +EQ L Q E +E ++ E ++
Sbjct: 1670 EKVAREEEKLAKKGGKLAEVKNILAQKVEELPQ--REQNLDWQEKELAQELEELEWDMEE 1727
Query: 108 LKQEKTQRDQQLNKQLEEEKKLLDQQ-----LDQELVKRDEQLGMKKEQLLELPEQQEGH 162
L ++ + +Q+ K +EE+KKL +++ ++L + + +L ++E L++ E+ H
Sbjct: 1728 LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQH 1787
Query: 163 LKHLEQQEGQLKHPEQQ--EGQLELPEQQEGQLELPEQ---------------------Q 199
+ + ++E +L +Q E +++L +++E + E+
Sbjct: 1788 KEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLA 1847
Query: 200 EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLE--LSEQQEGQLELSE 257
+ + +L +++E L E+ + Q + +L + + Q+E L++++E ++ E
Sbjct: 1848 QEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKE 1907
Query: 258 QQEGQLKHLEHQEGQLEVPEEQMGQLKY---LEQQEGQLK-------HLDQQEKQPELPE 307
+ K L E L +E++ Q K LE+ Q K + ++EK L
Sbjct: 1908 KLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEM 1967
Query: 308 QQMGQLK--------HLEQQEGQPKHLEQQEGQLEQ--------LEEQ----EGQLKHLE 347
+++ + K L + E +++ Q+EQ LEE+ E ++ +E
Sbjct: 1968 KRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAME 2027
Query: 348 QQE---GQLEHLEHQ----EGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQE 400
+ E G+LE Q +GQ L + +K+ E +P L + L+ L + E
Sbjct: 2028 ESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDE 2087
Query: 401 GQL---------------------------------------KHLVQQEGQLEQQERQVE 421
+L L + E +L +++R++
Sbjct: 2088 RKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLA 2147
Query: 422 H-LEQQVGQLKHLEEQEGQL--KHLE-----QQQGQLEVPE--QQVGQPKNLEQEEKQLE 471
+ + + + + + + E+E +L KH E +++G +E E + + +E K+ +
Sbjct: 2148 NKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGD 2207
Query: 472 LPEQQ-EGQVKHLEKQE----------AQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQL 520
P+++ QV +E +E +LE E + + ++E+ E E ++ +
Sbjct: 2208 KPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE 2267
Query: 521 KHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQE 577
+ E++EG+ K +E+++ + ++ +VQ+ + K E++ E + E
Sbjct: 2268 ERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDE 2324
Score = 58.9 bits (141), Expect = 1e-08
Identities = 66/337 (19%), Positives = 153/337 (45%), Gaps = 38/337 (11%)
Query: 50 ELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLK 109
E E SK KH + + E E +E + ++ W + +E ++ + P+++
Sbjct: 2158 EKMTEEESKLARKHSEVIL---DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFS 2214
Query: 110 QEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLE----------LPEQQ 159
+ + + + + EE + LLD+ QE + +E+ ++E+ E E++
Sbjct: 2215 SQVDEVESEEHFS-EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273
Query: 160 EGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ 219
EG K +E++E + K ++++ + E+ E++E +E + + E++ L E++
Sbjct: 2274 EGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE------VFEEKEEIMSEEETESLSDEEEE 2327
Query: 220 EGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQ------L 273
E L E+ + + E+ ++E Q +L EQ+ L E+ L+ + H +G+ L
Sbjct: 2328 EESCSLEEEVDREKEI-LKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVL 2386
Query: 274 EVPEE-------QMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQ---- 322
+ P + +M + + E Q+ D++ E+P + +G + + G+
Sbjct: 2387 KSPLKKLMSTALEMKEKTPVPVPEKQISWEDKKATVVEIPRKFLGTMDKEREVMGKYEPI 2446
Query: 323 PKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQ 359
P H+ + + + + + H+ ++ + E L+H+
Sbjct: 2447 PPHVLGTVLESQAQDLKTPFMSHILRRTVEAEELQHK 2483
Score = 48.9 bits (115), Expect = 1e-05
Identities = 67/315 (21%), Positives = 146/315 (46%), Gaps = 26/315 (8%)
Query: 49 VELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQ-- 106
+E + S++EE+ + E+ E++++ +E+E +++ E+ EE +K + E+
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296
Query: 107 ---QLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLG-----MKKEQLLELPEQ 158
Q K+E + +++ + EE + L D++ ++E +E++ +KKE+ +L EQ
Sbjct: 2297 EEVQEKEEVFEEKEEIMSE-EETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ 2355
Query: 159 QEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ 218
+ L+ E+ L+ +G+ + G L+ P ++ L +++ + +PE+
Sbjct: 2356 RRKSLRGRERVLSILRGVPHGKGR----AIRLGVLKSPLKKLMSTALEMKEKTPVPVPEK 2411
Query: 219 QEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLE-LSEQQEGQLKHLEHQEGQLEVPE 277
Q+ +++ +E+P++ G ++ + G+ E + G + LE Q L+ P
Sbjct: 2412 ---QISWEDKKATVVEIPRKFLGTMDKEREVMGKYEPIPPHVLGTV--LESQAQDLKTPF 2466
Query: 278 EQMGQLKYLEQQEGQLKHLDQQEK----QPELPEQQMGQLKHLEQQEGQPKHLEQQEGQL 333
+ +E +E Q K L K P L Q QL L Q + +H + +
Sbjct: 2467 MSHILRRTVEAEELQHKPLGAWWKWFLQHPPLMGQTEVQLP-LSQIPAKEQHADVSLSDV 2525
Query: 334 EQLEEQEGQLKHLEQ 348
E + +++ EQ
Sbjct: 2526 EWIRHVLERMEAGEQ 2540
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 89.0 bits (219), Expect = 1e-17
Identities = 110/497 (22%), Positives = 222/497 (44%), Gaps = 37/497 (7%)
Query: 76 EQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLD--QQ 133
+Q+ + +EQE+ + EE + E Q ++Q ++L++QLE+ K+ ++
Sbjct: 1165 QQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEK 1224
Query: 134 LDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQL 193
Q L +++L + + L ++ + E K L+ Q +L H + EG E E
Sbjct: 1225 NKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL-HAKVSEGDRLRVELAEKAS 1283
Query: 194 ELPEQQEGQLELPEQQEGQ--------LELPEQQEGQLELPEQQEGQ-----LELPQQQE 240
+L + + L E+ E + L Q + EL +++ Q + Q +E
Sbjct: 1284 KLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEE 1343
Query: 241 GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVP-EEQMGQLKYLEQQEGQL----KH 295
+ L EQQE + E + E Q+ L+ Q + ++ +G ++ LE+ + +L +
Sbjct: 1344 EKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEA 1403
Query: 296 LDQQEKQPELPEQQMGQLKHLEQQE--GQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQL 353
L Q+ ++ L ++ + K+ QQE L+ Q LE+++ + L +E +
Sbjct: 1404 LSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI 1463
Query: 354 EHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQL 413
+E E + + K L + + LE +E + Q ++ L+ + +
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523
Query: 414 EQQERQVEH----LEQQVGQLK-HLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEK 468
+ ++E LEQQV +++ LEE E +L+ E + +LEV Q + + + +
Sbjct: 1524 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTR 1583
Query: 469 QLELPEQQEGQVKHLEKQEAQLELPEQQ----VGQPKHLEQQEKHLEHP-----EQQDGQ 519
+ E++ +K + + EA+LE +Q V K +E K LE + +D
Sbjct: 1584 DEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEV 1643
Query: 520 LKHLEQQEGQLKDLEQQ 536
+K L + + Q+KD +++
Sbjct: 1644 IKQLRKLQAQMKDYQRE 1660
Score = 80.9 bits (198), Expect = 3e-15
Identities = 127/541 (23%), Positives = 244/541 (45%), Gaps = 38/541 (7%)
Query: 28 NTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQEL 87
N EQ++ T L +++ L + +E H ++ E+E E+ Q E++
Sbjct: 890 NILAEQLQAETELFAEAEEMRARLAAKKQELEEILH--DLESRVEEEEERNQILQNEKKK 947
Query: 88 QQQHWEQHEEY-QKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKR---DE 143
Q H + EE + E Q+L+ EK + ++ K++EEE LL+ Q + + ++ ++
Sbjct: 948 MQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKI-KKMEEEILLLEDQNSKFIKEKKLMED 1006
Query: 144 QLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQ-EGQ 202
++ QL E E+ + K +QE + E+ +L+ E+ +LE +++ +G+
Sbjct: 1007 RIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEE---RLKKEEKTRQELEKAKRKLDGE 1063
Query: 203 LELPEQQEGQLELPEQQEGQLELPEQQE--------GQLELPQQQEGQLELSEQQEGQLE 254
+ Q +L+ + E +L+L +++E G E + + E Q E
Sbjct: 1064 TTDLQDQIAELQ-AQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAE 1122
Query: 255 LSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLK 314
L E E + E Q E++ LK + E L Q++ EQ++ +LK
Sbjct: 1123 LQEDFESEKASRNKAEKQKRDLSEELEALK--TELEDTLDTTAAQQELRTKREQEVAELK 1180
Query: 315 H-LEQQ----EGQPKHLEQQEG-QLEQLEEQEGQLKHLEQQ-EGQLEHLEHQEGQLGLPE 367
LE++ E Q + + Q+ LE+L EQ Q K + E + LE +L E
Sbjct: 1181 KALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELAC-E 1239
Query: 368 QQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLK-HLVQQEGQLEQQERQVEHLEQQ 426
+VLQ + E + + K L+ + +L V + +L+ L ++ +L+ + V L ++
Sbjct: 1240 VKVLQQVKAESEH-KRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEE 1298
Query: 427 VGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQ 486
+ K ++ + Q Q E+ +++ Q NL +QLE E+ Q + E++
Sbjct: 1299 -AEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLE-EEKNSLQEQQEEEE 1356
Query: 487 EAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQ-LKDLEQQKGQLEQPVF 545
EA+ L +Q + L +K + + G ++ LE+ + + LKD E +LE+
Sbjct: 1357 EARKNLEKQVLALQSQLADTKKKV---DDDLGTIESLEEAKKKLLKDAEALSQRLEEKAL 1413
Query: 546 A 546
A
Sbjct: 1414 A 1414
Score = 79.3 bits (194), Expect = 9e-15
Identities = 112/488 (22%), Positives = 217/488 (44%), Gaps = 40/488 (8%)
Query: 73 QECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ 132
QE E Q K+ + +++++ + E ++ E QQL +EK +QL + E
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETE-------- 901
Query: 133 QLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQ 192
L E + +L KK++L E+ E ++ E++ Q+ E+++ Q + + +E Q
Sbjct: 902 -LFAEAEEMRARLAAKKQELEEILHDLESRVEE-EEERNQILQNEKKKMQAHIQDLEE-Q 958
Query: 193 LELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ-----QEGQLELPQQQEGQLELSE 247
L+ E +L+L E+ + ++ + +E L L +Q +E +L + E +L+E
Sbjct: 959 LDEEEGARQKLQL-EKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE 1017
Query: 248 QQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQ-EGQLKHLDQQ--EKQPE 304
++E L++ + Q + E +L+ E+ +L+ +++ +G+ L Q E Q +
Sbjct: 1018 EEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 305 LPEQQMGQLKHLEQQEG-------QPKHLEQQEGQLEQLEEQEGQLKH-LEQQEGQLEHL 356
+ E ++ K E+ +G + H + +L+ Q +L+ E ++
Sbjct: 1078 IDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA 1137
Query: 357 EHQEGQLGLPEQQVLQ------LKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQE 410
E Q+ L E + L+ L QQ E+E +LK +++E + H Q +
Sbjct: 1138 EKQKRDLS-EELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETK-NHEAQIQ 1195
Query: 411 GQLEQQERQVEHLEQQVGQLKHLEEQ-EGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQ 469
++ +E L +Q+ Q K + E + LE +L E +V Q E E K+
Sbjct: 1196 DMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELAC-EVKVLQQVKAESEHKR 1254
Query: 470 LELPEQ-QEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQL-KHLEQQE 527
+L Q QE K E ++EL E+ L+ LE E++ + K E
Sbjct: 1255 KKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLE 1314
Query: 528 GQLKDLEQ 535
QL+D ++
Sbjct: 1315 SQLQDTQE 1322
Score = 77.4 bits (189), Expect = 3e-14
Identities = 124/540 (22%), Positives = 240/540 (44%), Gaps = 75/540 (13%)
Query: 60 EEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKT------ 113
EEK + K + QQ+ + +L Q +K + +Q L +EK+
Sbjct: 1409 EEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYA 1468
Query: 114 -QRDQQLNKQLEEEKKLLDQ--------QLDQELVKRDEQLGMKKEQLLELPEQQEGHLK 164
+RD+ + E+E K L + +E ++++QL E L+ + ++
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 165 HLEQQEGQLKHP-EQQEGQLELPEQQEGQLELPEQQEGQLELPEQ-QEGQLELPEQQEGQ 222
LE+ + L+ E+ QLE + E +L+ E + +LE+ Q + Q E Q +
Sbjct: 1529 ELEKSKRALEQQVEEMRTQLE---ELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
Query: 223 LELPEQQEGQLELPQQQEGQLELSEQQEGQ---LELSEQQEGQLKHLEHQ-EGQLEVPEE 278
+++ +L + Q +E + EL ++++ + + ++ E LK LE Q E + +E
Sbjct: 1586 ---QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDE 1642
Query: 279 QMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEE 338
+ QL+ L+ Q ++ Q EL E + + + Q + K L+ E ++ QL+E
Sbjct: 1643 VIKQLRKLQAQ--------MKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 339 Q----EGQLKHLEQQEGQL--EHLEHQEGQLGLPEQQVLQLKQLEKQQGQ-PKHLEEEEG 391
+ E +H EQ+ +L E G+ L +++ ++LE + Q + LEEE+
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEK----RRLEARIAQLEEELEEEQS 1750
Query: 392 QLKHL--------VQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLK-HLEEQEGQLKH 442
++ L +Q + L + ++ + + LE+Q +LK L+E EG +K
Sbjct: 1751 NMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKS 1810
Query: 443 --------LEQQQGQLEVPEQQVGQP-----KNLEQEEKQL-ELPEQQEGQVKHLEKQEA 488
LE + GQLE +Q + K + + EK+L E+ Q E + +H ++ +
Sbjct: 1811 KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKE 1870
Query: 489 QLELPEQQVGQPK-HLEQQEKHLEHPEQQDGQLKH-----LEQQEGQLKDLEQQKGQLEQ 542
Q+E ++ Q K LE+ E+ +L+ E EG +++ K +L +
Sbjct: 1871 QMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
Score = 76.3 bits (186), Expect = 7e-14
Identities = 106/471 (22%), Positives = 228/471 (48%), Gaps = 47/471 (9%)
Query: 87 LQQQHWEQHEEYQKAENPEQQLKQEK--TQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQ 144
L+ +HW+ + K + Q +QE+ +D++L K E++ K+ + +E+ ++ +Q
Sbjct: 827 LKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGEL--EEMERKHQQ 884
Query: 145 LGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQ--------EGQLELPEQQEGQLELP 196
L +K L E + + E+ +L +Q+ E ++E E++ Q+
Sbjct: 885 LLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVE-EEEERNQILQN 943
Query: 197 EQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELS 256
E+++ Q + + +E QL+ E +L+L E+ + ++ + +E L L +Q ++
Sbjct: 944 EKKKMQAHIQDLEE-QLDEEEGARQKLQL-EKVTAEAKIKKMEEEILLLEDQNSKFIKEK 1001
Query: 257 EQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHL 316
+ E ++ Q + E + + +++ +QE + L+++ K+ E Q++ + K
Sbjct: 1002 KLMEDRIAECSSQLAEEEEKAKNLAKIR--NKQEVMISDLEERLKKEEKTRQELEKAK-- 1057
Query: 317 EQQEGQPKHLEQQEGQLE-QLEEQEGQL-KHLEQQEGQL----EHLEHQEGQLGLPEQQV 370
+ +G+ L+ Q +L+ Q++E + QL K E+ +G L + H+ L + +
Sbjct: 1058 RKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQ 1117
Query: 371 LQLKQLEKQ-QGQPKHLEEEEGQLKHLVQQEGQLKHLVQQ--EGQLEQQERQVEHLEQQV 427
Q+ +L++ + + + E Q + L ++ LK ++ + QQE + + EQ+V
Sbjct: 1118 AQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKR-EQEV 1176
Query: 428 GQLKH-LEEQ----EGQLKHLEQQQG-QLEVPEQQVGQPK----NLEQEEKQLELPEQQE 477
+LK LEE+ E Q++ + Q+ LE +Q+ Q K NLE+ ++ LE ++
Sbjct: 1177 AELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKEL 1236
Query: 478 G-QVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQE 527
+VK L++ +A+ E + K L+ Q + L H + +G +E E
Sbjct: 1237 ACEVKVLQQVKAESE------HKRKKLDAQVQEL-HAKVSEGDRLRVELAE 1280
Score = 65.1 bits (157), Expect = 2e-10
Identities = 102/459 (22%), Positives = 214/459 (46%), Gaps = 58/459 (12%)
Query: 68 KGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLK------QEKTQRDQQL-N 120
K + E E ++ E Q +E++ Q E +E Q E+ + +L+ + + +RD Q +
Sbjct: 1525 KNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRD 1584
Query: 121 KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQ-EGQLKHPEQQ 179
+Q EE+K+LL +Q+ +EL E ++ + ++ E LK LE Q E K ++
Sbjct: 1585 EQNEEKKRLLIKQV-RELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEV 1643
Query: 180 EGQLELPEQQ--EGQLELPEQQEGQLEL-PEQQEGQLELPEQQEGQLELPEQ---QEGQL 233
QL + Q + Q EL E + + E+ + +E + +L + L+L E+ E
Sbjct: 1644 IKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERAR 1703
Query: 234 ELPQQQEGQL--ELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEG 291
+Q+ +L E++ G+ L +++ + LE + QLE + LE+++
Sbjct: 1704 RHAEQERDELADEITNSASGKSALLDEK----RRLEARIAQLE---------EELEEEQS 1750
Query: 292 QLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLK-HLEQQE 350
++ L+ + ++ L + E+ Q + + +QLE Q +LK L++ E
Sbjct: 1751 NMELLNDRFRKTTLQVDTLNAELAAERSAAQ-----KSDNARQQLERQNKELKAKLQELE 1805
Query: 351 GQLEH-----LEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHL-VQQEGQLK 404
G ++ + E ++G E+Q+ Q + +++ K + E +LK + +Q E + +
Sbjct: 1806 GAVKSKFKATISALEAKIGQLEEQLEQ--EAKERAAANKLVRRTEKKLKEIFMQVEDERR 1863
Query: 405 HLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPE---------Q 455
H Q + Q+E+ +++ L++Q+ + E+E + +++ Q E+ + +
Sbjct: 1864 HADQYKEQMEKANARMKQLKRQLEE----AEEEATRANASRRKLQRELDDATEANEGLSR 1919
Query: 456 QVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPE 494
+V KN + + + G+ + L + A LEL +
Sbjct: 1920 EVSTLKNRLRRGGPISFSSSRSGR-RQLHLEGASLELSD 1957
Score = 40.4 bits (93), Expect = 0.005
Identities = 55/301 (18%), Positives = 129/301 (42%), Gaps = 38/301 (12%)
Query: 49 VELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQL 108
+E +E +K ++ + ++ L Q Q + ++EL++ + E + +++ E++L
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKL------QAQMKDYQRELEEARASRDEIFAQSKESEKKL 1682
Query: 109 K---------QEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKE---QLLELP 156
K QE+ ++ + E+E+ L ++ + L K+ ++ +L
Sbjct: 1683 KSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE 1742
Query: 157 EQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELP 216
E+ E ++E + + Q L + + ++ + + E+Q +L+
Sbjct: 1743 EELEEEQSNMELLNDRFRKTTLQVDTLNA--ELAAERSAAQKSDNARQQLERQNKELKAK 1800
Query: 217 EQQ-EGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEV 275
Q+ EG ++ + + + + + GQLE +QE ++++ K + E +L+
Sbjct: 1801 LQELEGAVK--SKFKATISALEAKIGQLEEQLEQE-----AKERAAANKLVRRTEKKLK- 1852
Query: 276 PEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLK-HLEQQEGQPKHLEQQEGQLE 334
+ Q E + +H DQ ++Q E +M QLK LE+ E + +L+
Sbjct: 1853 --------EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQ 1904
Query: 335 Q 335
+
Sbjct: 1905 R 1905
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.126 0.339
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,040,587
Number of Sequences: 37866
Number of extensions: 1858998
Number of successful extensions: 56771
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 662
Number of HSP's successfully gapped in prelim test: 1429
Number of HSP's that attempted gapping in prelim test: 9447
Number of HSP's gapped (non-prelim): 13671
length of query: 585
length of database: 18,247,518
effective HSP length: 108
effective length of query: 477
effective length of database: 14,157,990
effective search space: 6753361230
effective search space used: 6753361230
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.