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Search of human proteins with 42794752
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42794752 acyl-CoA synthetase long-chain family member 3
[Homo sapiens]
(720 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo... 1456 0.0
gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo... 1456 0.0
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo... 970 0.0
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 942 0.0
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 326 4e-89
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 326 4e-89
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 326 4e-89
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo... 323 3e-88
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo... 317 2e-86
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo... 315 1e-85
gi|27477105 lipidosin [Homo sapiens] 151 2e-36
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens] 137 5e-32
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 67 8e-11
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 67 8e-11
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 63 1e-09
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 43 0.001
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 43 0.001
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 42 0.003
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 39 0.017
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 38 0.029
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 38 0.038
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 37 0.084
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 36 0.11
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 36 0.11
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 35 0.32
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] 33 1.2
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 32 1.6
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 32 2.1
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 32 2.1
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 32 2.7
>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 1456 bits (3768), Expect = 0.0
Identities = 720/720 (100%), Positives = 720/720 (100%)
Query: 1 MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPV 60
MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPV
Sbjct: 1 MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPV 60
Query: 61 NSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPN 120
NSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPN
Sbjct: 61 NSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPN 120
Query: 121 GKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACF 180
GKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACF
Sbjct: 121 GKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACF 180
Query: 181 MYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGK 240
MYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGK
Sbjct: 181 MYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGK 240
Query: 241 PPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMIS 300
PPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMIS
Sbjct: 241 PPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMIS 300
Query: 301 HSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ 360
HSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ
Sbjct: 301 HSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ 360
Query: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
Query: 421 SKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTES 480
SKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTES
Sbjct: 421 SKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTES 480
Query: 481 AGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYY 540
AGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYY
Sbjct: 481 AGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYY 540
Query: 541 KNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAA 600
KNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAA
Sbjct: 541 KNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAA 600
Query: 601 LKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLK 660
LKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLK
Sbjct: 601 LKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLK 660
Query: 661 VLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK 720
VLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK
Sbjct: 661 VLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK 720
>gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 1456 bits (3768), Expect = 0.0
Identities = 720/720 (100%), Positives = 720/720 (100%)
Query: 1 MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPV 60
MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPV
Sbjct: 1 MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPV 60
Query: 61 NSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPN 120
NSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPN
Sbjct: 61 NSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPN 120
Query: 121 GKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACF 180
GKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACF
Sbjct: 121 GKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACF 180
Query: 181 MYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGK 240
MYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGK
Sbjct: 181 MYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGK 240
Query: 241 PPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMIS 300
PPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMIS
Sbjct: 241 PPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMIS 300
Query: 301 HSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ 360
HSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ
Sbjct: 301 HSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ 360
Query: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI
Sbjct: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
Query: 421 SKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTES 480
SKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTES
Sbjct: 421 SKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTES 480
Query: 481 AGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYY 540
AGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYY
Sbjct: 481 AGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYY 540
Query: 541 KNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAA 600
KNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAA
Sbjct: 541 KNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAA 600
Query: 601 LKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLK 660
LKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLK
Sbjct: 601 LKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLK 660
Query: 661 VLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK 720
VLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK
Sbjct: 661 VLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK 720
>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
2 [Homo sapiens]
Length = 711
Score = 970 bits (2508), Expect = 0.0
Identities = 466/711 (65%), Positives = 573/711 (80%), Gaps = 2/711 (0%)
Query: 12 MKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKS--NRIKAKPVNSKPDSAYR 69
MKLK + I+L +H LI++Y+ L +IP+YF + ++++ + RIKAKP + KP S YR
Sbjct: 1 MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYR 60
Query: 70 SVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIFKKVIL 129
SV D LA + PG DTLDK+F +A +KF K LGTRE+L+EE+E+QPNGK+FKK+IL
Sbjct: 61 SVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLIL 120
Query: 130 GQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189
G Y W++Y +V R NFG+GL LG KPK IAIFCETRAEWMIAAQ CF YNF LVTL
Sbjct: 121 GNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTL 180
Query: 190 YATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPK 249
YATLG A+VH LNE+E + +ITS ELL++KLK + + ++HII VD K +E+P+
Sbjct: 181 YATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPE 240
Query: 250 GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGIT 309
G +H+M +VE LG+ P S+P PSD+A++MYTSGSTG PKGVM+ HSN+IAG+T
Sbjct: 241 GFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMT 300
Query: 310 GMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSK 369
G ERIP LG +D YIGYLPLAHVLEL+AE+ C ++GCRIGYSSP TL+DQSSKIKKGSK
Sbjct: 301 GQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSK 360
Query: 370 GDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLC 429
GD ++LKPTLMAAVPEIMDRIYKNVM+KV EM+ Q+ LF + Y+YK+EQI KG + PLC
Sbjct: 361 GDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLC 420
Query: 430 DSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEV 489
+ +F+KV++LLGGN+R++L GGAPLS T RFMN+CFCCP+GQGYGLTES GAGT++EV
Sbjct: 421 NLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEV 480
Query: 490 WDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKAD 549
DY TGRVGAPL+CCEIKLK+W+EGGY DKP+PRGEI+IGGQ+++MGY+KNE KT D
Sbjct: 481 TDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAED 540
Query: 550 FFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDN 609
+ DENGQRW CTGDIGEF PDGCL+IIDRKKDLVKLQAGEYVSLGKVEAALKN PL+DN
Sbjct: 541 YSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDN 600
Query: 610 ICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLKVLSEAAISA 669
ICA+A S SYVI FVVPNQK LT LA++KG++GTW ++CN+ ME E+LK + EAA +
Sbjct: 601 ICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAM 660
Query: 670 SLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK 720
LE+FEIP+K+RLSPEPWTPETGLVTDAFKLKRKEL+ HY DIERMYG K
Sbjct: 661 KLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK 711
>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
[Homo sapiens]
Length = 670
Score = 942 bits (2435), Expect = 0.0
Identities = 451/669 (67%), Positives = 545/669 (81%)
Query: 52 SNRIKAKPVNSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVL 111
+ RIKAKP + KP S YRSV D LA + PG DTLDK+F +A +KF K LGTRE+L
Sbjct: 2 AKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREIL 61
Query: 112 NEEDEVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAE 171
+EE+E+QPNGK+FKK+ILG Y W++Y +V R NFG+GL LG KPK IAIFCETRAE
Sbjct: 62 SEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAE 121
Query: 172 WMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRL 231
WMIAAQ CF YNF LVTLYATLG A+VH LNE+E + +ITS ELL++KLK + + +
Sbjct: 122 WMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCV 181
Query: 232 RHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGST 291
+HII VD K +E+P+G +H+M +VE LG+ P S+P PSD+A++MYTSGST
Sbjct: 182 KHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGST 241
Query: 292 GLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY 351
G PKGVM+ HSN+IAG+TG ERIP LG +D YIGYLPLAHVLEL+AE+ C ++GCRIGY
Sbjct: 242 GRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGY 301
Query: 352 SSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFIL 411
SSP TL+DQSSKIKKGSKGD ++LKPTLMAAVPEIMDRIYKNVM+KV EM+ Q+ LF +
Sbjct: 302 SSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKI 361
Query: 412 AYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPV 471
Y+YK+EQI KG + PLC+ +F+KV++LLGGN+R++L GGAPLS T RFMN+CFCCP+
Sbjct: 362 GYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPI 421
Query: 472 GQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIG 531
GQGYGLTES GAGT++EV DY TGRVGAPL+CCEIKLK+W+EGGY DKP+PRGEI+IG
Sbjct: 422 GQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIG 481
Query: 532 GQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEY 591
GQ+++MGY+KNE KT D+ DENGQRW CTGDIGEF PDGCL+IIDRKKDLVKLQAGEY
Sbjct: 482 GQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEY 541
Query: 592 VSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNS 651
VSLGKVEAALKN PL+DNICA+A S SYVI FVVPNQK LT LA++KG++GTW ++CN+
Sbjct: 542 VSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNN 601
Query: 652 CEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQA 711
ME E+LK + EAA + LE+FEIP+K+RLSPEPWTPETGLVTDAFKLKRKEL+ HY
Sbjct: 602 PAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLK 661
Query: 712 DIERMYGRK 720
DIERMYG K
Sbjct: 662 DIERMYGGK 670
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 326 bits (836), Expect = 4e-89
Identities = 211/599 (35%), Positives = 314/599 (52%), Gaps = 36/599 (6%)
Query: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189
Y WLSY+ V RA G+ L G K P + IF + R EW+I+ AC+ Y+ V L
Sbjct: 103 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 162
Query: 190 YATLGGPAIVHALNETEVTNII--TSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEF 247
Y TLG AIVH +N+ ++ +I T ++ L P L+ II +D +
Sbjct: 163 YDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQR 222
Query: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
+ GI + ++ E LG + + P P P D++VI +TSG+TG PKG MI+H NI+
Sbjct: 223 GEKSGIEILSLYDAENLGKEHFRKPVP---PSPEDLSVICFTSGTTGDPKGAMITHQNIV 279
Query: 306 AGITGMAERIPELGE---EDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
+ + + E +DV I YLPLAH+ E + V S G R+G+ + LAD
Sbjct: 280 SNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLAD- 338
Query: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
D LKPTL AVP +++RIY V N+ + ++ L LA + K +++
Sbjct: 339 ----------DMKTLKPTLFPAVPRLLNRIYDKVQNEAK--TPLKKFLLKLAVSSKFKEL 386
Query: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
KG R+ D +F K++ LGG +R+++ G AP+S + F C V + YG T
Sbjct: 387 QKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQT 446
Query: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
E G T + D+ +G VG PL C +KL++ + YF + GE+ I G +V G
Sbjct: 447 ECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN---EGEVCIKGTNVFKG 503
Query: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Y K+ KT+ D +G WL TGDIG + P+G LKIIDRKK++ KL GEY++ K+E
Sbjct: 504 YLKDPEKTQEAL--DSDG--WLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIE 559
Query: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
V I + S S ++G VVP+ L A K G+KG++EELC + + +
Sbjct: 560 NIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQVVREAI 619
Query: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
L+ L + + L+ FE I L PEP++ E GL+T K KR EL +++ I+ +Y
Sbjct: 620 LEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFRTQIDSLY 678
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 326 bits (836), Expect = 4e-89
Identities = 211/599 (35%), Positives = 314/599 (52%), Gaps = 36/599 (6%)
Query: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189
Y WLSY+ V RA G+ L G K P + IF + R EW+I+ AC+ Y+ V L
Sbjct: 103 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 162
Query: 190 YATLGGPAIVHALNETEVTNII--TSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEF 247
Y TLG AIVH +N+ ++ +I T ++ L P L+ II +D +
Sbjct: 163 YDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQR 222
Query: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
+ GI + ++ E LG + + P P P D++VI +TSG+TG PKG MI+H NI+
Sbjct: 223 GEKSGIEILSLYDAENLGKEHFRKPVP---PSPEDLSVICFTSGTTGDPKGAMITHQNIV 279
Query: 306 AGITGMAERIPELGE---EDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
+ + + E +DV I YLPLAH+ E + V S G R+G+ + LAD
Sbjct: 280 SNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLAD- 338
Query: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
D LKPTL AVP +++RIY V N+ + ++ L LA + K +++
Sbjct: 339 ----------DMKTLKPTLFPAVPRLLNRIYDKVQNEAK--TPLKKFLLKLAVSSKFKEL 386
Query: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
KG R+ D +F K++ LGG +R+++ G AP+S + F C V + YG T
Sbjct: 387 QKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQT 446
Query: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
E G T + D+ +G VG PL C +KL++ + YF + GE+ I G +V G
Sbjct: 447 ECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN---EGEVCIKGTNVFKG 503
Query: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Y K+ KT+ D +G WL TGDIG + P+G LKIIDRKK++ KL GEY++ K+E
Sbjct: 504 YLKDPEKTQEAL--DSDG--WLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIE 559
Query: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
V I + S S ++G VVP+ L A K G+KG++EELC + + +
Sbjct: 560 NIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQVVREAI 619
Query: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
L+ L + + L+ FE I L PEP++ E GL+T K KR EL +++ I+ +Y
Sbjct: 620 LEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFRTQIDSLY 678
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 326 bits (836), Expect = 4e-89
Identities = 211/599 (35%), Positives = 314/599 (52%), Gaps = 36/599 (6%)
Query: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189
Y WLSY+ V RA G+ L G K P + IF + R EW+I+ AC+ Y+ V L
Sbjct: 159 YRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPL 218
Query: 190 YATLGGPAIVHALNETEVTNII--TSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEF 247
Y TLG AIVH +N+ ++ +I T ++ L P L+ II +D +
Sbjct: 219 YDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQR 278
Query: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
+ GI + ++ E LG + + P P P D++VI +TSG+TG PKG MI+H NI+
Sbjct: 279 GEKSGIEILSLYDAENLGKEHFRKPVP---PSPEDLSVICFTSGTTGDPKGAMITHQNIV 335
Query: 306 AGITGMAERIPELGE---EDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
+ + + E +DV I YLPLAH+ E + V S G R+G+ + LAD
Sbjct: 336 SNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLAD- 394
Query: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
D LKPTL AVP +++RIY V N+ + ++ L LA + K +++
Sbjct: 395 ----------DMKTLKPTLFPAVPRLLNRIYDKVQNEAK--TPLKKFLLKLAVSSKFKEL 442
Query: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
KG R+ D +F K++ LGG +R+++ G AP+S + F C V + YG T
Sbjct: 443 QKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQT 502
Query: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
E G T + D+ +G VG PL C +KL++ + YF + GE+ I G +V G
Sbjct: 503 ECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNN---EGEVCIKGTNVFKG 559
Query: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Y K+ KT+ D +G WL TGDIG + P+G LKIIDRKK++ KL GEY++ K+E
Sbjct: 560 YLKDPEKTQEAL--DSDG--WLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIE 615
Query: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
V I + S S ++G VVP+ L A K G+KG++EELC + + +
Sbjct: 616 NIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQVVREAI 675
Query: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
L+ L + + L+ FE I L PEP++ E GL+T K KR EL +++ I+ +Y
Sbjct: 676 LEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLKAKRGELSKYFRTQIDSLY 734
>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
sapiens]
Length = 698
Score = 323 bits (828), Expect = 3e-88
Identities = 205/599 (34%), Positives = 321/599 (53%), Gaps = 36/599 (6%)
Query: 132 YNWLSYEDVFVRAFNFGNGLQMLGQK--PKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189
Y WLSY+ V + G+ L G K P I IF + R EW+I Q CF Y+ +V L
Sbjct: 118 YEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPL 177
Query: 190 YATLGGPAIVHALNETEVTNIITSK-ELLQTKLKDIVS-LVPRLRHIITVDGKPPTWSEF 247
Y TLG AI + +N+ E++ + K E + L+ + + L+P L+ I+ +D E
Sbjct: 178 YDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVER 237
Query: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
+ G+ V +M A+E LG + +P P P D+AVI +TSG+TG PKG M++H NI+
Sbjct: 238 GQRCGVEVTSMKAMEDLGRANRRKPKP---PAPEDLAVICFTSGTTGNPKGAMVTHRNIV 294
Query: 306 AGITGMA---ERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
+ + E +D I +LPLAH+ E E V L HG +IG+ + L D
Sbjct: 295 SDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVMLCHGAKIGFFQGDIRLLMD- 353
Query: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
D +L+PT+ VP +++R++ + + + ++ +R L A K ++
Sbjct: 354 ----------DLKVLQPTVFPVVPRLLNRMFDRIFGQAN--TTLKRWLLDFASKRKEAEL 401
Query: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
G RN L D +F KV+S LGG +RL++ G AP+SAT F+ C +GYG T
Sbjct: 402 RSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQT 461
Query: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
E ++ D+ G VGAP+ C IKL + EE Y + GE+ + G +V G
Sbjct: 462 ECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEG---EGEVCVKGPNVFQG 518
Query: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Y K+ AKT D++G WL TGDIG++ P+G LKIIDRKK + KL GEY++ K+E
Sbjct: 519 YLKDPAKTAEAL--DKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIE 574
Query: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
V + + S +++I VVP+ + L A+K+G +G++EELC + +++ +
Sbjct: 575 NIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEELCRNKDVKKAI 634
Query: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
L+ + + L+ FE I L PE ++ + GL+T K KR EL+ ++++ I+ +Y
Sbjct: 635 LEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLY 693
>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
b [Homo sapiens]
Length = 722
Score = 317 bits (812), Expect = 2e-86
Identities = 198/599 (33%), Positives = 319/599 (53%), Gaps = 36/599 (6%)
Query: 132 YNWLSYEDVFVRAFNFGNGLQMLGQKPKTN--IAIFCETRAEWMIAAQACFMYNFQLVTL 189
Y WLSY++V RA G+GL K T+ I +F + R EW+I AC+ Y+ +V L
Sbjct: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
Query: 190 YATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSL--VPRLRHIITVDGKPPTWSEF 247
Y TLG AI + +N +++ +I K L + V P L+ II +D E
Sbjct: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKER 262
Query: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
+ G+++ +M AVE G + +Q P P D++++ +TSG+TG PKG M++H N++
Sbjct: 263 GQKCGVVIKSMQAVEDCGQE---NHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVV 319
Query: 306 AGITG---MAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
A +G + E++ ++DV I +LPLAH+ E + V HG R+G+ + L+D
Sbjct: 320 ADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSD- 378
Query: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
D L PT+ VP +++R+Y + ++ + + +R L A K ++
Sbjct: 379 ----------DMKALCPTIFPVVPRLLNRMYDKIFSQAN--TPLKRWLLEFAAKRKQAEV 426
Query: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
G RN + D F K+++ LGG +R+++ G AP S T F+ C V +GYG T
Sbjct: 427 RSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQT 486
Query: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
E T + D+ +G VGAPL C IKL + EE Y+ GEI + G +V G
Sbjct: 487 ECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKG---EGEICVRGPNVFKG 543
Query: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Y K+ +TK D +G WL TGDIG++ P G LKIIDRKK + KL GEYV+ K+E
Sbjct: 544 YLKDPDRTKEAL--DSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIE 599
Query: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
V I + +S ++++G VVP+ + + A+K+G++GT+ +LC + +++ +
Sbjct: 600 NIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAI 659
Query: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
L+ + + L FE I + + ++ + GL+T K KR EL+ +++ IE +Y
Sbjct: 660 LEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
a [Homo sapiens]
Length = 722
Score = 315 bits (806), Expect = 1e-85
Identities = 198/599 (33%), Positives = 315/599 (52%), Gaps = 36/599 (6%)
Query: 132 YNWLSYEDVFVRAFNFGNGLQMLGQKPKTN--IAIFCETRAEWMIAAQACFMYNFQLVTL 189
Y WLSY++V RA G+GL K T+ I +F + R EW+I AC+ Y+ +V L
Sbjct: 143 YQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPL 202
Query: 190 YATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSL--VPRLRHIITVDGKPPTWSEF 247
Y TLG AI + +N +++ +I K L + V P L+ II +D E
Sbjct: 203 YDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKER 262
Query: 248 PK--GIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNII 305
+ G+++ +M AVE G + +Q P P D++++ +TSG+TG PKG M++H N++
Sbjct: 263 GQKCGVVIKSMQAVEDCGQE---NHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVV 319
Query: 306 AGITGMAERIPELGEE---DVYIGYLPLAHVLELSAELVCLSHGCRIGY--SSPQTLADQ 360
A +G + DV+I YLPLAH+ E + V HG R+G+ + L+D
Sbjct: 320 ADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSD- 378
Query: 361 SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI 420
D L PT+ VP +++R+Y + ++ + + +R L A K ++
Sbjct: 379 ----------DMKALCPTIFPVVPRLLNRMYDKIFSQAN--TPLKRWLLEFAAKRKQAEV 426
Query: 421 SKG--RNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLT 478
G RN + D F K+++ LGG +R+++ G AP S T F+ C V +GYG T
Sbjct: 427 RSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQT 486
Query: 479 ESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMG 538
E T + D+ +G VGAPL C IKL + EE Y+ GEI + G +V G
Sbjct: 487 ECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKG---EGEICVRGPNVFKG 543
Query: 539 YYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
Y K+ +TK D +G WL TGDIG++ P G LKIIDRKK + KL GEYV+ K+E
Sbjct: 544 YLKDPDRTKEAL--DSDG--WLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIE 599
Query: 599 AALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEV 658
V I + +S ++++G VVP+ + + A+K+G++GT+ +LC + +++ +
Sbjct: 600 NIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAI 659
Query: 659 LKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717
L+ + + L FE I + + ++ + GL+T K KR EL+ +++ IE +Y
Sbjct: 660 LEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELY 718
>gi|27477105 lipidosin [Homo sapiens]
Length = 724
Score = 151 bits (381), Expect = 2e-36
Identities = 138/495 (27%), Positives = 216/495 (43%), Gaps = 43/495 (8%)
Query: 131 QYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLY 190
++ +SY ++ A G LG K ++AI EW +A + +Y
Sbjct: 129 KWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIY 188
Query: 191 ATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKG 250
T A + + I+ + K+ I +P L+ ++ PP K
Sbjct: 189 TTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPN-----KM 243
Query: 251 IIVHTMAAVEALGAKASME--NQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNI--IA 306
V+TM LG + E + P+ V++YTSG+TG PKGVM+S NI A
Sbjct: 244 ANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTA 303
Query: 307 GITGMAERI-PELGEEDVYIGYLPLAHVLELSAEL-VCLSHGCRIGYSSPQTLADQSSKI 364
A I P +++V + YLPL+H+ +L + G ++ ++ P L
Sbjct: 304 RYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDAL------- 356
Query: 365 KKGSKGDT-SMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQ---- 419
KGS +T ++PT VP + ++I + + ++ +R + + A + +EQ
Sbjct: 357 -KGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTC 415
Query: 420 ---ISKGRNTPLCDSFVFRKVRSLLG-GNIRLLLCGGAPLSATTQRFMNICFCCPVGQGY 475
K T L D V KVR LG + G AP+ A TQ F + + GY
Sbjct: 416 PGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFF-LGLNIRLYAGY 474
Query: 476 GLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSV 535
GL+E++G +S ++Y G + C +KL N + G GEI + G+++
Sbjct: 475 GLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGI---------GEICLWGRTI 525
Query: 536 TMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLG 595
MGY E KT DE G WL TGD G + DG L I R K+L+ GE V
Sbjct: 526 FMGYLNMEDKTCEAI--DEEG--WLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPV 581
Query: 596 KVEAALK-NLPLVDN 609
+E A+K LP++ N
Sbjct: 582 PIEEAVKMELPIISN 596
>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
Length = 666
Score = 137 bits (344), Expect = 5e-32
Identities = 130/495 (26%), Positives = 225/495 (45%), Gaps = 53/495 (10%)
Query: 135 LSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLG 194
L++ + L LG + + I AEW I A + V +YAT
Sbjct: 81 LNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNS 140
Query: 195 GPAIVHALNETEVTNIITSKELLQTKLKDIV--SLVPRLRHIITV------DGKPPTWSE 246
+ + +V ++ + K+ I SL P L+ II + +W +
Sbjct: 141 AEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLEP-LKAIIQYRLPMKKNNNLYSWDD 199
Query: 247 FPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNI-- 304
F + ++ + +E+Q ++ AV++YTSG+TG+PKGVM+SH NI
Sbjct: 200 F-----MELGRSIPDTQLEQVIESQKANQ-----CAVLIYTSGTTGIPKGVMLSHDNITW 249
Query: 305 IAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKI 364
IAG ++ + + + + YLPL+H+ +A+++ + +IG T Q+ +
Sbjct: 250 IAGAVTKDFKLTD--KHETVVSYLPLSHI---AAQMMDIWVPIKIG---ALTYFAQADAL 301
Query: 365 KKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGR 424
K +KPT+ VP+I ++I++ V ++ ++ F+ A N + SK
Sbjct: 302 KGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGFKVNSKKM 361
Query: 425 ----NTP----LCDSFVFRKVRSLLG-GNIRLLLCGGAPLSATTQRFMNICFCCPVGQGY 475
NTP + + VF KV++ LG + + G APL+ T F + P+G+ Y
Sbjct: 362 LGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFF-LSLDIPIGELY 420
Query: 476 GLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSV 535
GL+ES+G TIS +Y G L C+ L + G GEI + G+ +
Sbjct: 421 GLSESSGPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGI---------GEICLWGRHI 471
Query: 536 TMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLG 595
MGY ++E +T + +DE WL +GD+G+ + G L + K+++ GE V
Sbjct: 472 FMGYLESETET-TEAIDDEG---WLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPI 527
Query: 596 KVEAAL-KNLPLVDN 609
VE + K +P++ N
Sbjct: 528 PVETLVKKKIPIISN 542
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 66.6 bits (161), Expect = 8e-11
Identities = 119/516 (23%), Positives = 204/516 (39%), Gaps = 105/516 (20%)
Query: 128 ILGQYNWLSYEDVFVRAFNFGNGLQML-----GQKPKTNIAIFCETRAEWMIAAQACFMY 182
++ Q+ +Y +++ R+ + L G + ++ C A +++A A +M
Sbjct: 59 LVDQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMS 118
Query: 183 NFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPP 242
V LY + + + +++ + ++ S+E L+ L P +R + G P
Sbjct: 119 GGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLEL-------LSPVVRKL----GVPL 167
Query: 243 TWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDI-----AVIMYTSGSTGLPKGV 297
P ++T A E P P+P A+I+YTSG+TG PKGV
Sbjct: 168 ----LPLTPAIYTGAVEE-----------PAEVPVPEQGWRNKGAMIIYTSGTTGRPKGV 212
Query: 298 MISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTL 357
+ +H NI A +TG+ + ++DV + LPL HV + L+C P +
Sbjct: 213 LSTHQNIRAVVTGLVHKW-AWTKDDVILHVLPLHHVHGVVNALLC-----------PLWV 260
Query: 358 ADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILA---YN 414
G T ++ P + V K + + N+F+ Y
Sbjct: 261 ------------GATCVMMPEFSP----------QQVWEKFLSSETPRINVFMAVPTIYT 298
Query: 415 YKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLS-ATTQRFMNICFCCPVGQ 473
ME + P F +R++ IRL++ G A L +++ NI + +
Sbjct: 299 KLMEYYDRHFTQPHAQDF----LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLL-E 353
Query: 474 GYGLTE--SAGAGTISEVWDYNTGRVGAPLVCCEIKL----------------KNWEEGG 515
YG+TE A +G ++ G VG PL ++++ + E G
Sbjct: 354 RYGMTEIGMALSGPLTTAVRL-PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGT 412
Query: 516 YFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLK 575
GE+L+ G SV Y+ +TK+ F D W TGD F+ DG
Sbjct: 413 KVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLD----GWFKTGDTVVFK-DGQYW 467
Query: 576 IIDRKK-DLVKLQAGEYVSLGKVEAALKNLPLVDNI 610
I R D++K G VS +VE L P + ++
Sbjct: 468 IRGRTSVDIIK-TGGYKVSALEVEWHLLAHPSITDV 502
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 66.6 bits (161), Expect = 8e-11
Identities = 119/516 (23%), Positives = 204/516 (39%), Gaps = 105/516 (20%)
Query: 128 ILGQYNWLSYEDVFVRAFNFGNGLQML-----GQKPKTNIAIFCETRAEWMIAAQACFMY 182
++ Q+ +Y +++ R+ + L G + ++ C A +++A A +M
Sbjct: 59 LVDQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMS 118
Query: 183 NFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPP 242
V LY + + + +++ + ++ S+E L+ L P +R + G P
Sbjct: 119 GGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLEL-------LSPVVRKL----GVPL 167
Query: 243 TWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDI-----AVIMYTSGSTGLPKGV 297
P ++T A E P P+P A+I+YTSG+TG PKGV
Sbjct: 168 ----LPLTPAIYTGAVEE-----------PAEVPVPEQGWRNKGAMIIYTSGTTGRPKGV 212
Query: 298 MISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTL 357
+ +H NI A +TG+ + ++DV + LPL HV + L+C P +
Sbjct: 213 LSTHQNIRAVVTGLVHKW-AWTKDDVILHVLPLHHVHGVVNALLC-----------PLWV 260
Query: 358 ADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILA---YN 414
G T ++ P + V K + + N+F+ Y
Sbjct: 261 ------------GATCVMMPEFSP----------QQVWEKFLSSETPRINVFMAVPTIYT 298
Query: 415 YKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLS-ATTQRFMNICFCCPVGQ 473
ME + P F +R++ IRL++ G A L +++ NI + +
Sbjct: 299 KLMEYYDRHFTQPHAQDF----LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLL-E 353
Query: 474 GYGLTE--SAGAGTISEVWDYNTGRVGAPLVCCEIKL----------------KNWEEGG 515
YG+TE A +G ++ G VG PL ++++ + E G
Sbjct: 354 RYGMTEIGMALSGPLTTAVRL-PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGT 412
Query: 516 YFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLK 575
GE+L+ G SV Y+ +TK+ F D W TGD F+ DG
Sbjct: 413 KVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLD----GWFKTGDTVVFK-DGQYW 467
Query: 576 IIDRKK-DLVKLQAGEYVSLGKVEAALKNLPLVDNI 610
I R D++K G VS +VE L P + ++
Sbjct: 468 IRGRTSVDIIK-TGGYKVSALEVEWHLLAHPSITDV 502
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 62.8 bits (151), Expect = 1e-09
Identities = 73/334 (21%), Positives = 132/334 (39%), Gaps = 62/334 (18%)
Query: 284 IMYTSGSTGLPKGVMISHSNIIAGITGMAERIP---ELGEEDVYIGYLPLAHVL-ELSAE 339
I +TSG+TG PKG +SH NI+ + ER+ + E+ I PL H L ++
Sbjct: 260 IQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGT 319
Query: 340 LVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVS 399
++CL +G + +SP ++ + +G PT+ + +++N+
Sbjct: 320 MMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTM-----------FVDILNQ-P 367
Query: 400 EMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATT 459
+ SS+ + ++ GG ++ G
Sbjct: 368 DFSSYD-------------------------------ISTMCGG----VIAGSPAPPELI 392
Query: 460 QRFMNICFCCPVGQGYGLTESAG---AGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGY 516
+ +N + YG TE++ A + + VG + E ++ N E G
Sbjct: 393 RAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTL 452
Query: 517 FNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKI 576
+ P GE+ I G V +GY+ KT+ +D +W TGD+ G KI
Sbjct: 453 AKLNTP---GELCIRGYCVMLGYWGEPQKTEEAVDQD----KWYWTGDVATMNEQGFCKI 505
Query: 577 IDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNI 610
+ R KD++ ++ GE + ++E P V +
Sbjct: 506 VGRSKDMI-IRGGENIYPAELEDFFHTHPKVQEV 538
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/66 (43%), Positives = 37/66 (56%), Gaps = 6/66 (9%)
Query: 282 AVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELV 341
A+ +YTSG+TGLPK MI+H I G TG+ + L +DV LP H SA L+
Sbjct: 220 ALYIYTSGTTGLPKAAMITHQRIWYG-TGLT-FVSGLKADDVIYITLPFYH----SAALL 273
Query: 342 CLSHGC 347
HGC
Sbjct: 274 IGIHGC 279
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 19/100 (19%)
Query: 259 VEALGAKASMENQPHSKPLPSDI---------AVIMYTSGSTGLPKGVMISHSNIIAGIT 309
V ALGA +++ P S P+P+D+ A+ +YTSG+TGLPK +++H ++
Sbjct: 261 VGALGA--ALDAAP-SHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQ--- 314
Query: 310 GMAERIPELG--EEDVYIGYLPLAHVLELSAELV-CLSHG 346
M++ + G +DV LPL HV+ L ++ CL G
Sbjct: 315 -MSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLG 353
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 41.6 bits (96), Expect = 0.003
Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 15/171 (8%)
Query: 155 GQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSK 214
G +P + + EW + + AC ++ L + + L + +IITS
Sbjct: 111 GLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITS- 169
Query: 215 ELLQTKLKDIVSLVPRLR-HIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPH 273
+ L ++ I + P L+ ++ D P W F E L ++ N
Sbjct: 170 DSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFR-----------ELLREASTEHNCMR 218
Query: 274 SKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVY 324
+K D I +TSG+TG PK V S S+ G R L E D++
Sbjct: 219 TKS--RDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIF 267
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 38.9 bits (89), Expect = 0.017
Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 19/157 (12%)
Query: 152 QMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNII 211
Q G + ++A+ EW + A C + L I++ L ++ I+
Sbjct: 104 QTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIV 163
Query: 212 TSKELLQTKLKDIVSLVPRLR-HIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMEN 270
T + L +++ I S P L+ ++ D W +F +L AS E+
Sbjct: 164 TI-DALASEVDSIASQCPSLKTKLLVSDHSREGWLDF------------RSLVKSASPEH 210
Query: 271 Q-PHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIA 306
SK L D VI +TSG+TG PK M HS+ +A
Sbjct: 211 TCVKSKTL--DPMVIFFTSGTTGFPK--MAKHSHGLA 243
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 38.1 bits (87), Expect = 0.029
Identities = 37/142 (26%), Positives = 62/142 (43%), Gaps = 15/142 (10%)
Query: 471 VGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILI 530
+ + YG TE+ +S+ G +G C ++++ + ++G N P G+I I
Sbjct: 357 IRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIID-DKG---NVLPPGTEGDIGI 412
Query: 531 GGQ-----SVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVK 585
+ + GY N KT A+ G WL GD G + DG + + R D++
Sbjct: 413 RVKPIRPIGIFSGYVDNPDKTAANI----RGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467
Query: 586 LQAGEYVSLGKVEAALKNLPLV 607
+G + +VE AL P V
Sbjct: 468 -SSGYRIGPSEVENALMEHPAV 488
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 37.7 bits (86), Expect = 0.038
Identities = 39/176 (22%), Positives = 74/176 (42%), Gaps = 23/176 (13%)
Query: 135 LSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLG 194
++Y ++ N L+ G +AI+ + A AC ++A
Sbjct: 141 ITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFS 200
Query: 195 GPAIVHALNETEVTNIITSKELLQ----TKLKDIVSLV----PRLRHIITV---DGKPPT 243
++ +N+ + +IT + L+ +LK IV P ++H++ D K
Sbjct: 201 AESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHM 260
Query: 244 WS-EFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVM 298
+ P + MA + + A SM ++ D+ ++YTSGSTG+PKG++
Sbjct: 261 GDLDVP---LEQEMAKEDPVCAPESMGSE--------DMLFMLYTSGSTGMPKGIV 305
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 36.6 bits (83), Expect = 0.084
Identities = 89/457 (19%), Positives = 160/457 (35%), Gaps = 87/457 (19%)
Query: 162 IAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKL 221
+A+ EW + AC + L I++ L ++ I+ S+E+ +
Sbjct: 117 LAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPA-V 175
Query: 222 KDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDI 281
+ IV P L+ + V P +W+ + + A+ E + + +P+
Sbjct: 176 ESIVLECPDLKTKLLVS--PQSWNGWLSFQELFQFASEEHSCVETGSQ-----EPM---- 224
Query: 282 AVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELV 341
I +TSG+TG PK S S++ G T +L D+
Sbjct: 225 -TIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDII----------------- 266
Query: 342 CLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEM 401
+ DT +K AA+ + V M
Sbjct: 267 -------------------------WNMSDTGWVK----AAIGSVFSSWLCGACVFVHRM 297
Query: 402 SSFQRNLFILAYNYKMEQISKGRNTPLCDS------FVFRKVRSLLGGNIRLLLCGGAPL 455
+ F + F+ + ++ T LC V + ++ ++R L GG PL
Sbjct: 298 AQFDTDTFL-------DTLTTYPITTLCSPPTVYRMLVQKDLKRYKFKSLRHCLTGGEPL 350
Query: 456 SATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGG 515
+ + + +GYG TE + + G +G ++ ++++ +E G
Sbjct: 351 NPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPYDVQII--DENG 408
Query: 516 YFNTDKPHPRGEILIGGQSVT-----MGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEP 570
N P GEI + + Y N KT A D + TGD G +
Sbjct: 409 --NVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGD-----FYVTGDRGVMDS 461
Query: 571 DGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLV 607
DG + R D++ + +G + +VE+AL P V
Sbjct: 462 DGYFWFVGRADDVI-ISSGYRIGPFEVESALIEHPAV 497
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 36.2 bits (82), Expect = 0.11
Identities = 50/211 (23%), Positives = 80/211 (37%), Gaps = 28/211 (13%)
Query: 149 NGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVT 208
N LQ G AIF E R E++ + + L A++H L +
Sbjct: 116 NFLQARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRAR 175
Query: 209 NIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASM 268
++ E+ + SL P L + +P G + + ++ L +
Sbjct: 176 ALVFGSEMASAICEVHASLDPSLSLFCSGSWEP--------GAVPPSTEHLDPL-----L 222
Query: 269 ENQPHSKPLPS-------DIAVIMYTSGSTGLPKGVMISHSNI--IAGITGMAERIPELG 319
++ P K LPS D +YTSG+TGLPK ++ HS +A + R +
Sbjct: 223 KDAP--KHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFR---MR 277
Query: 320 EEDVYIGYLPLAHVL-ELSAELVCLSHGCRI 349
D+ LPL H + CL HG +
Sbjct: 278 PNDIVYDCLPLYHSAGNIVGIGQCLLHGMTV 308
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 36.2 bits (82), Expect = 0.11
Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 10/139 (7%)
Query: 195 GPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVH 254
GP ++H L ++ + E L++ D+ +L H+ P T ++
Sbjct: 251 GP-LLHCLRSCGARALVLAPEFLESLEPDLPALRAMGLHLWAAG--PGTHPAGISDLLAE 307
Query: 255 TMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAER 314
A V+ G + P S +D + ++TSG+TGLPK ISH I+ G +
Sbjct: 308 VSAEVD--GPVPGYLSSPQSI---TDTCLYIFTSGTTGLPKAARISHLKILQ-CQGFYQ- 360
Query: 315 IPELGEEDVYIGYLPLAHV 333
+ + +EDV LPL H+
Sbjct: 361 LCGVHQEDVIYLALPLYHM 379
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 34.7 bits (78), Expect = 0.32
Identities = 42/228 (18%), Positives = 82/228 (35%), Gaps = 38/228 (16%)
Query: 130 GQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTL 189
G+ ++Y + V+ F N L+ G + +AI+ E ++A AC +
Sbjct: 131 GETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIV 190
Query: 190 YATLGGPAIVHALNETEVTNIITSKELLQ-TKLKDIVSLVPRLRHIITVDGKPPTWSEFP 248
+A ++ + ++ + +IT+ + KL ++ L G P
Sbjct: 191 FAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEKGFPVRCC--- 247
Query: 249 KGIIVHTMAAVEALGAKASMENQPHSKPLPS----------------------------- 279
I+V + E ++ ++ P + P
Sbjct: 248 --IVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISWNQGIDLWWHELMQEAGDECEPEWC 305
Query: 280 ---DIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVY 324
D I+YTSGSTG PKGV+ + + + + + + EDV+
Sbjct: 306 DAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVF 353
>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
Length = 1098
Score = 32.7 bits (73), Expect = 1.2
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Query: 281 IAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAEL 340
+A +++TSG+TG+PK V + H I+ I + ++ +EDV PL +
Sbjct: 192 LAYVLHTSGTTGIPKIVRVPHKCIVPNIQHF-RVLFDITQEDVLFLASPLTFDPSVVEIF 250
Query: 341 VCLSHGCRI 349
+ LS G +
Sbjct: 251 LALSSGASL 259
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 32.3 bits (72), Expect = 1.6
Identities = 47/190 (24%), Positives = 72/190 (37%), Gaps = 20/190 (10%)
Query: 149 NGLQMLGQKPKTNIAIFCETRAE----WMIAAQACFMYNFQLVTLYATLGGPAIVHALNE 204
N + LG P +AIF E R E W+ A+A + L L + L
Sbjct: 118 NLFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAKA----GMEAALLNVNLRREPLAFCLGT 173
Query: 205 TEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGII--VHTMAAVEAL 262
+ +I E++ + L L + D P +GI+ H + +
Sbjct: 174 SGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGP-------EGILPDTHLLDPLLKE 226
Query: 263 GAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEED 322
+ A + P SK + D +YTSG+TGLPK ++ HS + + D
Sbjct: 227 ASTAPLAQIP-SKGM-DDRLFYIYTSGTTGLPKAAIVVHSRYYR-MAAFGHHAYRMQAAD 283
Query: 323 VYIGYLPLAH 332
V LPL H
Sbjct: 284 VLYDCLPLYH 293
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 32.0 bits (71), Expect = 2.1
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 210 IITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASME 269
++ +LL T + ++P L I+V G + P+G+I ++ + +
Sbjct: 156 LVVGADLLGT----VEEILPSLSENISVWGMKDS---VPQGVI--SLKEKLSTSPDEPVP 206
Query: 270 NQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAG 307
H L + ++TSG+TGLPK +IS ++ G
Sbjct: 207 RSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRG 244
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 32.0 bits (71), Expect = 2.1
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 210 IITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASME 269
++ +LL T + ++P L I+V G + P+G+I ++ + +
Sbjct: 156 LVVGADLLGT----VEEILPSLSENISVWGMKDS---VPQGVI--SLKEKLSTSPDEPVP 206
Query: 270 NQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAG 307
H L + ++TSG+TGLPK +IS ++ G
Sbjct: 207 RSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRG 244
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 31.6 bits (70), Expect = 2.7
Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 171 EWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPR 230
EW +A AC L+ L I++ L ++ IIT+ ++L + + S
Sbjct: 132 EWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCEN 190
Query: 231 LRH-IITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSG 289
L +I + W K ++ H + ++ K ++I I +TSG
Sbjct: 191 LHSKLIVSENSREGWGNL-KELMKH------------ASDSHTCVKTKHNEIMAIFFTSG 237
Query: 290 STGLPKGVMISHSNIIAGIT 309
++G PK +HS+ G++
Sbjct: 238 TSGYPKMTAHTHSSFGLGLS 257
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,259,088
Number of Sequences: 37866
Number of extensions: 1240504
Number of successful extensions: 2711
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2615
Number of HSP's gapped (non-prelim): 43
length of query: 720
length of database: 18,247,518
effective HSP length: 110
effective length of query: 610
effective length of database: 14,082,258
effective search space: 8590177380
effective search space used: 8590177380
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.