Guide to the Human Genome
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Search of human proteins with 42741679

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2
[Homo sapiens]
         (856 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Ho...  1724   0.0  
gi|194097403 ATPase, H+ transporting, lysosomal V0 subunit a1 is...   885   0.0  
gi|194097401 ATPase, H+ transporting, lysosomal V0 subunit a1 is...   884   0.0  
gi|19913418 ATPase, H+ transporting, lysosomal V0 subunit a1 iso...   883   0.0  
gi|85386547 ATPase, H+ transporting, lysosomal V0 subunit a4 [Ho...   852   0.0  
gi|85386056 ATPase, H+ transporting, lysosomal V0 subunit a4 [Ho...   852   0.0  
gi|85386053 ATPase, H+ transporting, lysosomal V0 subunit a4 [Ho...   852   0.0  
gi|19924145 T-cell, immune regulator 1 isoform a [Homo sapiens]       818   0.0  
gi|5174717 T-cell, immune regulator 1 isoform b [Homo sapiens]        652   0.0  
gi|45505178 cancer antigen 1 [Homo sapiens]                            37   0.078
gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-l...    36   0.13 
gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-l...    36   0.13 
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact...    35   0.23 
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    35   0.23 
gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.23 
gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.30 
gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein...    35   0.30 
gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein...    35   0.30 
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein...    35   0.30 
gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-l...    35   0.30 
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    35   0.30 
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    35   0.30 
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    35   0.39 
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l...    34   0.51 
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l...    34   0.51 
gi|50083279 centrosome protein 4 [Homo sapiens]                        34   0.51 
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    34   0.66 
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    34   0.66 
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           34   0.66 
gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-l...    33   0.86 

>gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Homo
           sapiens]
          Length = 856

 Score = 1724 bits (4464), Expect = 0.0
 Identities = 856/856 (100%), Positives = 856/856 (100%)

Query: 1   MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE 60
           MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE
Sbjct: 1   MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE 60

Query: 61  LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK 120
           LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK
Sbjct: 61  LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK 120

Query: 121 NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQRLGAKLGFVSGLI 180
           NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQRLGAKLGFVSGLI
Sbjct: 121 NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQRLGAKLGFVSGLI 180

Query: 181 NQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVKK 240
           NQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVKK
Sbjct: 181 NQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVKK 240

Query: 241 ICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRVI 300
           ICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRVI
Sbjct: 241 ICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRVI 300

Query: 301 QVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFMNII 360
           QVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFMNII
Sbjct: 301 QVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFMNII 360

Query: 361 PTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGFV 420
           PTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGFV
Sbjct: 361 PTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGFV 420

Query: 421 MFLFALLLVLNENHPRLNQSQEIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVNLFG 480
           MFLFALLLVLNENHPRLNQSQEIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVNLFG
Sbjct: 421 MFLFALLLVLNENHPRLNQSQEIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVNLFG 480

Query: 481 SGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRGPYPLGIDPIWNLA 540
           SGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRGPYPLGIDPIWNLA
Sbjct: 481 SGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRGPYPLGIDPIWNLA 540

Query: 541 TNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLCIFGY 600
           TNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLCIFGY
Sbjct: 541 TNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLCIFGY 600

Query: 601 LIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSGLYTGQEYVQRVLLVVTALSV 660
           LIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSGLYTGQEYVQRVLLVVTALSV
Sbjct: 601 LIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSGLYTGQEYVQRVLLVVTALSV 660

Query: 661 PVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQVEDGCRE 720
           PVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQVEDGCRE
Sbjct: 661 PVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQVEDGCRE 720

Query: 721 MACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLR 780
           MACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLR
Sbjct: 721 MACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLR 780

Query: 781 VDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPF 840
           VDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPF
Sbjct: 781 VDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPF 840

Query: 841 SFSLLSSKFNNDDSVA 856
           SFSLLSSKFNNDDSVA
Sbjct: 841 SFSLLSSKFNNDDSVA 856


>gi|194097403 ATPase, H+ transporting, lysosomal V0 subunit a1
           isoform b [Homo sapiens]
          Length = 837

 Score =  885 bits (2287), Expect = 0.0
 Identities = 453/849 (53%), Positives = 602/849 (70%), Gaps = 29/849 (3%)

Query: 1   MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE 60
           MG LFRSE M LAQLFLQS  AY C+S LGE G VQFRDLN +V+ FQRKFV EV+RCEE
Sbjct: 1   MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE 60

Query: 61  LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK 120
           ++R L ++ +EI +A+IP+ +   +P  P  + +++++   +K+E EL+E+  N+E L++
Sbjct: 61  MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR 120

Query: 121 NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSL--ESDSLLDYSCMQR-LGAKLGFVS 177
           N LEL E   +LR T+ F     +        P L  ES SLL+ S M R    +LGFV+
Sbjct: 121 NFLELTELKFILRKTQQFFDEMAD--------PDLLEESSSLLEPSEMGRGTPLRLGFVA 172

Query: 178 GLINQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHK 237
           G+IN+ ++  FE+MLWRVC+G   +  AE++  LEDP TG+ +   VF+I F G+Q+ ++
Sbjct: 173 GVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNR 232

Query: 238 VKKICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYS 297
           VKKIC+ +   +YP P T +ER+E+  G+NTRI DL  VL++TED+ ++VL  AA+++  
Sbjct: 233 VKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRV 292

Query: 298 RVIQVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFM 357
             I+V+KMKAIYH LN+C+ DVT KCLIAEVWCP  DL  ++ AL  G+  SG+T+PS +
Sbjct: 293 WFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSIL 352

Query: 358 NIIPTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGH 417
           N + T +TPPT  +TNKFT GFQNIVDAYG+G+YRE+NPA +TIITFPFLFAVMFGDFGH
Sbjct: 353 NRMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGH 412

Query: 418 GFVMFLFALLLVLNENHPRLNQSQ-EIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSV 476
           G +M LFA+ +VL E+     +++ E+    F+GRYI+LLMG+FS+YTGLIYNDCFSKS+
Sbjct: 413 GILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSL 472

Query: 477 NLFGSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRGPYPLGIDPI 536
           N+FGS W+V  M++ +           W +  +R N +LQL+P++PGVF GPYP GIDPI
Sbjct: 473 NIFGSSWSVRPMFTYN-----------WTEETLRGNPVLQLNPALPGVFGGPYPFGIDPI 521

Query: 537 WNLATNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLC 596
           WN+ATN+LTFLNSFKMKMSVILGIIHM FGV L +FNH++F+K  NIY   IPE++FM  
Sbjct: 522 WNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTS 581

Query: 597 IFGYLIFMIFYKWLVFSAETSRVAPSILIEFINMFLF--PASKTSGLYTGQEYVQRVLLV 654
           +FGYL+ +IFYKW  + A TS  APS+LI FINMFLF  P S  S LY+GQ+ +Q  L+V
Sbjct: 582 LFGYLVILIFYKWTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVV 641

Query: 655 VTALSVPVLFLGKPLFLLWLHNGRSCFG-VNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQ 713
           V  L VP + L KPL L   +  R   G +N  G  +    +EE+  ++    +   +  
Sbjct: 642 VALLCVPWMLLFKPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSED 701

Query: 714 VEDGCREMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAM 773
            ++   +   E F+FG+ ++ Q IH+IEYCLGCISNTASYLRLWALSLAHAQLS+VLW M
Sbjct: 702 ADEPSED---EVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTM 758

Query: 774 LMRVGLRVDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGA 833
           ++ +GL V +  G L+L      FA LT+ ILLIMEGLSAFLHA+RLHWVEFQNKFY G 
Sbjct: 759 VIHIGLSVKSLAGGLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGT 818

Query: 834 GTKFVPFSF 842
           G KF+PFSF
Sbjct: 819 GFKFLPFSF 827


>gi|194097401 ATPase, H+ transporting, lysosomal V0 subunit a1
           isoform a [Homo sapiens]
          Length = 838

 Score =  884 bits (2284), Expect = 0.0
 Identities = 454/849 (53%), Positives = 600/849 (70%), Gaps = 28/849 (3%)

Query: 1   MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE 60
           MG LFRSE M LAQLFLQS  AY C+S LGE G VQFRDLN +V+ FQRKFV EV+RCEE
Sbjct: 1   MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE 60

Query: 61  LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK 120
           ++R L ++ +EI +A+IP+ +   +P  P  + +++++   +K+E EL+E+  N+E L++
Sbjct: 61  MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR 120

Query: 121 NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSL--ESDSLLDYSCMQR-LGAKLGFVS 177
           N LEL E   +LR T+ F     E        P L  ES SLL+ S M R    +LGFV+
Sbjct: 121 NFLELTELKFILRKTQQFFDE-AELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVA 179

Query: 178 GLINQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHK 237
           G+IN+ ++  FE+MLWRVC+G   +  AE++  LEDP TG+ +   VF+I F G+Q+ ++
Sbjct: 180 GVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNR 239

Query: 238 VKKICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYS 297
           VKKIC+ +   +YP P T +ER+E+  G+NTRI DL  VL++TED+ ++VL  AA+++  
Sbjct: 240 VKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRV 299

Query: 298 RVIQVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFM 357
             I+V+KMKAIYH LN+C+ DVT KCLIAEVWCP  DL  ++ AL  G+  SG+T+PS +
Sbjct: 300 WFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSIL 359

Query: 358 NIIPTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGH 417
           N + T +TPPT  +TNKFT GFQNIVDAYG+G+YRE+NPA +TIITFPFLFAVMFGDFGH
Sbjct: 360 NRMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGH 419

Query: 418 GFVMFLFALLLVLNENHPRLNQSQ-EIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSV 476
           G +M LFA+ +VL E+     +++ E+    F+GRYI+LLMG+FS+YTGLIYNDCFSKS+
Sbjct: 420 GILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSL 479

Query: 477 NLFGSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRGPYPLGIDPI 536
           N+FGS W+V  M++ +           W +  +R N +LQL+P++PGVF GPYP GIDPI
Sbjct: 480 NIFGSSWSVRPMFTYN-----------WTEETLRGNPVLQLNPALPGVFGGPYPFGIDPI 528

Query: 537 WNLATNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLC 596
           WN+ATN+LTFLNSFKMKMSVILGIIHM FGV L +FNH++F+K  NIY   IPE++FM  
Sbjct: 529 WNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTS 588

Query: 597 IFGYLIFMIFYKWLVFSAETSRVAPSILIEFINMFLF--PASKTSGLYTGQEYVQRVLLV 654
           +FGYL+ +IFYKW  + A TS  APS+LI FINMFLF  P S  S LY+GQ+ +Q  L+V
Sbjct: 589 LFGYLVILIFYKWTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVV 648

Query: 655 VTALSVPVLFLGKPLFLLWLHNGRSCFG-VNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQ 713
           V  L VP + L KPL L   +  R   G +N  G  +    +EE+  ++    +   +  
Sbjct: 649 VALLCVPWMLLFKPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSED 708

Query: 714 VEDGCREMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAM 773
                     +EF+FG+ ++ Q IH+IEYCLGCISNTASYLRLWALSLAHAQLS+VLW M
Sbjct: 709 ---------ADEFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTM 759

Query: 774 LMRVGLRVDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGA 833
           ++ +GL V +  G L+L      FA LT+ ILLIMEGLSAFLHA+RLHWVEFQNKFY G 
Sbjct: 760 VIHIGLSVKSLAGGLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGT 819

Query: 834 GTKFVPFSF 842
           G KF+PFSF
Sbjct: 820 GFKFLPFSF 828


>gi|19913418 ATPase, H+ transporting, lysosomal V0 subunit a1
           isoform c [Homo sapiens]
          Length = 831

 Score =  883 bits (2282), Expect = 0.0
 Identities = 453/849 (53%), Positives = 600/849 (70%), Gaps = 35/849 (4%)

Query: 1   MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE 60
           MG LFRSE M LAQLFLQS  AY C+S LGE G VQFRDLN +V+ FQRKFV EV+RCEE
Sbjct: 1   MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE 60

Query: 61  LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK 120
           ++R L ++ +EI +A+IP+ +   +P  P  + +++++   +K+E EL+E+  N+E L++
Sbjct: 61  MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR 120

Query: 121 NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSL--ESDSLLDYSCMQR-LGAKLGFVS 177
           N LEL E   +LR T+ F     +        P L  ES SLL+ S M R    +LGFV+
Sbjct: 121 NFLELTELKFILRKTQQFFDEMAD--------PDLLEESSSLLEPSEMGRGTPLRLGFVA 172

Query: 178 GLINQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHK 237
           G+IN+ ++  FE+MLWRVC+G   +  AE++  LEDP TG+ +   VF+I F G+Q+ ++
Sbjct: 173 GVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNR 232

Query: 238 VKKICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYS 297
           VKKIC+ +   +YP P T +ER+E+  G+NTRI DL  VL++TED+ ++VL  AA+++  
Sbjct: 233 VKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRV 292

Query: 298 RVIQVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFM 357
             I+V+KMKAIYH LN+C+ DVT KCLIAEVWCP  DL  ++ AL  G+  SG+T+PS +
Sbjct: 293 WFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSIL 352

Query: 358 NIIPTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGH 417
           N + T +TPPT  +TNKFT GFQNIVDAYG+G+YRE+NPA +TIITFPFLFAVMFGDFGH
Sbjct: 353 NRMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGH 412

Query: 418 GFVMFLFALLLVLNENHPRLNQSQ-EIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSV 476
           G +M LFA+ +VL E+     +++ E+    F+GRYI+LLMG+FS+YTGLIYNDCFSKS+
Sbjct: 413 GILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSL 472

Query: 477 NLFGSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRGPYPLGIDPI 536
           N+FGS W+V  M++ +           W +  +R N +LQL+P++PGVF GPYP GIDPI
Sbjct: 473 NIFGSSWSVRPMFTYN-----------WTEETLRGNPVLQLNPALPGVFGGPYPFGIDPI 521

Query: 537 WNLATNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLC 596
           WN+ATN+LTFLNSFKMKMSVILGIIHM FGV L +FNH++F+K  NIY   IPE++FM  
Sbjct: 522 WNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTS 581

Query: 597 IFGYLIFMIFYKWLVFSAETSRVAPSILIEFINMFLF--PASKTSGLYTGQEYVQRVLLV 654
           +FGYL+ +IFYKW  + A TS  APS+LI FINMFLF  P S  S LY+GQ+ +Q  L+V
Sbjct: 582 LFGYLVILIFYKWTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVV 641

Query: 655 VTALSVPVLFLGKPLFLLWLHNGRSCFG-VNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQ 713
           V  L VP + L KPL L   +  R   G +N  G  +    +EE+  ++    +   +  
Sbjct: 642 VALLCVPWMLLFKPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSED 701

Query: 714 VEDGCREMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAM 773
                     +EF+FG+ ++ Q IH+IEYCLGCISNTASYLRLWALSLAHAQLS+VLW M
Sbjct: 702 ---------ADEFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTM 752

Query: 774 LMRVGLRVDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVGA 833
           ++ +GL V +  G L+L      FA LT+ ILLIMEGLSAFLHA+RLHWVEFQNKFY G 
Sbjct: 753 VIHIGLSVKSLAGGLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGT 812

Query: 834 GTKFVPFSF 842
           G KF+PFSF
Sbjct: 813 GFKFLPFSF 821


>gi|85386547 ATPase, H+ transporting, lysosomal V0 subunit a4 [Homo
           sapiens]
          Length = 840

 Score =  852 bits (2202), Expect = 0.0
 Identities = 445/851 (52%), Positives = 599/851 (70%), Gaps = 30/851 (3%)

Query: 1   MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE 60
           M S+FRSE MCL+QLFLQ   AY C++ LGE GLVQF+DLN NV+SFQRKFV EV+RCE 
Sbjct: 1   MVSVFRSEEMCLSQLFLQVEAAYCCVAELGELGLVQFKDLNMNVNSFQRKFVNEVRRCES 60

Query: 61  LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK 120
           LERIL +L  E+   +I +   E SP  P  ++++ ++  L+KLE EL+E  +N++ L++
Sbjct: 61  LERILRFLEDEMQN-EIVVQLLEKSPLTPLPREMITLETVLEKLEGELQEANQNQQALKQ 119

Query: 121 NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQR-LGAKLGFVSGL 179
           + LEL E  ++L+ T+ F +         ++F + ++  LL+   +   +  KLGF++G+
Sbjct: 120 SFLELTELKYLLKKTQDFFETETNLA---DDFFTEDTSGLLELKAVPAYMTGKLGFIAGV 176

Query: 180 INQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVK 239
           IN+ ++ +FE++LWR+C+G   + ++E+D  LEDP T E I+  +F+I + GEQ+  K+K
Sbjct: 177 INRERMASFERLLWRICRGNVYLKFSEMDAPLEDPVTKEEIQKNIFIIFYQGEQLRQKIK 236

Query: 240 KICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRV 299
           KICD +   VYP P  A ERRE+ E +N R++DL TV+ +TE + +++L +AA + +S +
Sbjct: 237 KICDGFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHRQRLLQEAAANWHSWL 296

Query: 300 IQVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFMNI 359
           I+V+KMKA+YH+LNMC+ DVT +C+IAE+W P AD   ++RALE+G   SG+++   M  
Sbjct: 297 IKVQKMKAVYHILNMCNIDVTQQCVIAEIWFPVADATRIKRALEQGMELSGSSMAPIMTT 356

Query: 360 IPTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGF 419
           + +K  PPT  RTNKFT GFQNIVDAYGVGSYRE+NPA +TIITFPFLFAVMFGD GHG 
Sbjct: 357 VQSKTAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGT 416

Query: 420 VMFLFALLLVLNENHPRLNQ--SQEIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVN 477
           VM L AL ++LNE    L+Q    EI   FF+GRY++LLMG+FS+YTGLIYNDCFSKS+N
Sbjct: 417 VMLLAALWMILNERR-LLSQKTDNEIWNTFFHGRYLILLMGIFSIYTGLIYNDCFSKSLN 475

Query: 478 LFGSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRG-PYPLGIDPI 536
           +FGS W+V  M+ +            WN  V+  +  LQLDP+IPGV+ G PYP GIDPI
Sbjct: 476 IFGSSWSVQPMFRNG----------TWNTHVMEESLYLQLDPAIPGVYFGNPYPFGIDPI 525

Query: 537 WNLATNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLC 596
           WNLA+N+LTFLNS+KMKMSVILGI+ M FGVIL +FNH++FR+  NI L  IPE++F+LC
Sbjct: 526 WNLASNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMIFILC 585

Query: 597 IFGYLIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSG--LYTGQEYVQRVLLV 654
           +FGYL+FMI +KW  F    S+ APSILI FINMFLF  S +S   LY  Q+ VQ   +V
Sbjct: 586 LFGYLVFMIIFKWCCFDVHVSQHAPSILIHFINMFLFNYSDSSNAPLYKHQQEVQSFFVV 645

Query: 655 VTALSVPVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQV 714
           +  +SVP + L KP F+L   + +S    +R     I++D+ E +    S        + 
Sbjct: 646 MALISVPWMLLIKP-FILRASHRKSQLQASR-----IQEDATENIEGDSSSPSSRSGQRT 699

Query: 715 E---DGCREMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLW 771
                G  +   EEFNFG++ + Q IH+IEYCLGCISNTASYLRLWALSLAHAQLS+VLW
Sbjct: 700 SADTHGALDDHGEEFNFGDVFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW 759

Query: 772 AMLMRVGLRVDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYV 831
            M+M  GL+     G++ +  + A+FAVLT+ ILLIMEGLSAFLHA+RLHWVEFQNKFYV
Sbjct: 760 TMVMNSGLQTRGWGGIVGVFIIFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYV 819

Query: 832 GAGTKFVPFSF 842
           G G KF PFSF
Sbjct: 820 GDGYKFSPFSF 830


>gi|85386056 ATPase, H+ transporting, lysosomal V0 subunit a4 [Homo
           sapiens]
          Length = 840

 Score =  852 bits (2202), Expect = 0.0
 Identities = 445/851 (52%), Positives = 599/851 (70%), Gaps = 30/851 (3%)

Query: 1   MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE 60
           M S+FRSE MCL+QLFLQ   AY C++ LGE GLVQF+DLN NV+SFQRKFV EV+RCE 
Sbjct: 1   MVSVFRSEEMCLSQLFLQVEAAYCCVAELGELGLVQFKDLNMNVNSFQRKFVNEVRRCES 60

Query: 61  LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK 120
           LERIL +L  E+   +I +   E SP  P  ++++ ++  L+KLE EL+E  +N++ L++
Sbjct: 61  LERILRFLEDEMQN-EIVVQLLEKSPLTPLPREMITLETVLEKLEGELQEANQNQQALKQ 119

Query: 121 NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQR-LGAKLGFVSGL 179
           + LEL E  ++L+ T+ F +         ++F + ++  LL+   +   +  KLGF++G+
Sbjct: 120 SFLELTELKYLLKKTQDFFETETNLA---DDFFTEDTSGLLELKAVPAYMTGKLGFIAGV 176

Query: 180 INQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVK 239
           IN+ ++ +FE++LWR+C+G   + ++E+D  LEDP T E I+  +F+I + GEQ+  K+K
Sbjct: 177 INRERMASFERLLWRICRGNVYLKFSEMDAPLEDPVTKEEIQKNIFIIFYQGEQLRQKIK 236

Query: 240 KICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRV 299
           KICD +   VYP P  A ERRE+ E +N R++DL TV+ +TE + +++L +AA + +S +
Sbjct: 237 KICDGFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHRQRLLQEAAANWHSWL 296

Query: 300 IQVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFMNI 359
           I+V+KMKA+YH+LNMC+ DVT +C+IAE+W P AD   ++RALE+G   SG+++   M  
Sbjct: 297 IKVQKMKAVYHILNMCNIDVTQQCVIAEIWFPVADATRIKRALEQGMELSGSSMAPIMTT 356

Query: 360 IPTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGF 419
           + +K  PPT  RTNKFT GFQNIVDAYGVGSYRE+NPA +TIITFPFLFAVMFGD GHG 
Sbjct: 357 VQSKTAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGT 416

Query: 420 VMFLFALLLVLNENHPRLNQ--SQEIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVN 477
           VM L AL ++LNE    L+Q    EI   FF+GRY++LLMG+FS+YTGLIYNDCFSKS+N
Sbjct: 417 VMLLAALWMILNERR-LLSQKTDNEIWNTFFHGRYLILLMGIFSIYTGLIYNDCFSKSLN 475

Query: 478 LFGSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRG-PYPLGIDPI 536
           +FGS W+V  M+ +            WN  V+  +  LQLDP+IPGV+ G PYP GIDPI
Sbjct: 476 IFGSSWSVQPMFRNG----------TWNTHVMEESLYLQLDPAIPGVYFGNPYPFGIDPI 525

Query: 537 WNLATNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLC 596
           WNLA+N+LTFLNS+KMKMSVILGI+ M FGVIL +FNH++FR+  NI L  IPE++F+LC
Sbjct: 526 WNLASNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMIFILC 585

Query: 597 IFGYLIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSG--LYTGQEYVQRVLLV 654
           +FGYL+FMI +KW  F    S+ APSILI FINMFLF  S +S   LY  Q+ VQ   +V
Sbjct: 586 LFGYLVFMIIFKWCCFDVHVSQHAPSILIHFINMFLFNYSDSSNAPLYKHQQEVQSFFVV 645

Query: 655 VTALSVPVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQV 714
           +  +SVP + L KP F+L   + +S    +R     I++D+ E +    S        + 
Sbjct: 646 MALISVPWMLLIKP-FILRASHRKSQLQASR-----IQEDATENIEGDSSSPSSRSGQRT 699

Query: 715 E---DGCREMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLW 771
                G  +   EEFNFG++ + Q IH+IEYCLGCISNTASYLRLWALSLAHAQLS+VLW
Sbjct: 700 SADTHGALDDHGEEFNFGDVFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW 759

Query: 772 AMLMRVGLRVDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYV 831
            M+M  GL+     G++ +  + A+FAVLT+ ILLIMEGLSAFLHA+RLHWVEFQNKFYV
Sbjct: 760 TMVMNSGLQTRGWGGIVGVFIIFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYV 819

Query: 832 GAGTKFVPFSF 842
           G G KF PFSF
Sbjct: 820 GDGYKFSPFSF 830


>gi|85386053 ATPase, H+ transporting, lysosomal V0 subunit a4 [Homo
           sapiens]
          Length = 840

 Score =  852 bits (2202), Expect = 0.0
 Identities = 445/851 (52%), Positives = 599/851 (70%), Gaps = 30/851 (3%)

Query: 1   MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE 60
           M S+FRSE MCL+QLFLQ   AY C++ LGE GLVQF+DLN NV+SFQRKFV EV+RCE 
Sbjct: 1   MVSVFRSEEMCLSQLFLQVEAAYCCVAELGELGLVQFKDLNMNVNSFQRKFVNEVRRCES 60

Query: 61  LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK 120
           LERIL +L  E+   +I +   E SP  P  ++++ ++  L+KLE EL+E  +N++ L++
Sbjct: 61  LERILRFLEDEMQN-EIVVQLLEKSPLTPLPREMITLETVLEKLEGELQEANQNQQALKQ 119

Query: 121 NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQR-LGAKLGFVSGL 179
           + LEL E  ++L+ T+ F +         ++F + ++  LL+   +   +  KLGF++G+
Sbjct: 120 SFLELTELKYLLKKTQDFFETETNLA---DDFFTEDTSGLLELKAVPAYMTGKLGFIAGV 176

Query: 180 INQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVK 239
           IN+ ++ +FE++LWR+C+G   + ++E+D  LEDP T E I+  +F+I + GEQ+  K+K
Sbjct: 177 INRERMASFERLLWRICRGNVYLKFSEMDAPLEDPVTKEEIQKNIFIIFYQGEQLRQKIK 236

Query: 240 KICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRV 299
           KICD +   VYP P  A ERRE+ E +N R++DL TV+ +TE + +++L +AA + +S +
Sbjct: 237 KICDGFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHRQRLLQEAAANWHSWL 296

Query: 300 IQVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFMNI 359
           I+V+KMKA+YH+LNMC+ DVT +C+IAE+W P AD   ++RALE+G   SG+++   M  
Sbjct: 297 IKVQKMKAVYHILNMCNIDVTQQCVIAEIWFPVADATRIKRALEQGMELSGSSMAPIMTT 356

Query: 360 IPTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGF 419
           + +K  PPT  RTNKFT GFQNIVDAYGVGSYRE+NPA +TIITFPFLFAVMFGD GHG 
Sbjct: 357 VQSKTAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGT 416

Query: 420 VMFLFALLLVLNENHPRLNQ--SQEIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVN 477
           VM L AL ++LNE    L+Q    EI   FF+GRY++LLMG+FS+YTGLIYNDCFSKS+N
Sbjct: 417 VMLLAALWMILNERR-LLSQKTDNEIWNTFFHGRYLILLMGIFSIYTGLIYNDCFSKSLN 475

Query: 478 LFGSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRG-PYPLGIDPI 536
           +FGS W+V  M+ +            WN  V+  +  LQLDP+IPGV+ G PYP GIDPI
Sbjct: 476 IFGSSWSVQPMFRNG----------TWNTHVMEESLYLQLDPAIPGVYFGNPYPFGIDPI 525

Query: 537 WNLATNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLC 596
           WNLA+N+LTFLNS+KMKMSVILGI+ M FGVIL +FNH++FR+  NI L  IPE++F+LC
Sbjct: 526 WNLASNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMIFILC 585

Query: 597 IFGYLIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSG--LYTGQEYVQRVLLV 654
           +FGYL+FMI +KW  F    S+ APSILI FINMFLF  S +S   LY  Q+ VQ   +V
Sbjct: 586 LFGYLVFMIIFKWCCFDVHVSQHAPSILIHFINMFLFNYSDSSNAPLYKHQQEVQSFFVV 645

Query: 655 VTALSVPVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLLGSQDIEEGNHQV 714
           +  +SVP + L KP F+L   + +S    +R     I++D+ E +    S        + 
Sbjct: 646 MALISVPWMLLIKP-FILRASHRKSQLQASR-----IQEDATENIEGDSSSPSSRSGQRT 699

Query: 715 E---DGCREMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLW 771
                G  +   EEFNFG++ + Q IH+IEYCLGCISNTASYLRLWALSLAHAQLS+VLW
Sbjct: 700 SADTHGALDDHGEEFNFGDVFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW 759

Query: 772 AMLMRVGLRVDTTYGVLLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYV 831
            M+M  GL+     G++ +  + A+FAVLT+ ILLIMEGLSAFLHA+RLHWVEFQNKFYV
Sbjct: 760 TMVMNSGLQTRGWGGIVGVFIIFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYV 819

Query: 832 GAGTKFVPFSF 842
           G G KF PFSF
Sbjct: 820 GDGYKFSPFSF 830


>gi|19924145 T-cell, immune regulator 1 isoform a [Homo sapiens]
          Length = 830

 Score =  818 bits (2114), Expect = 0.0
 Identities = 426/851 (50%), Positives = 564/851 (66%), Gaps = 33/851 (3%)

Query: 1   MGSLFRSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEE 60
           MGS+FRSE + L QLFL +  AY C+S LGE GLV+FRDLN +VS+FQR+FV +V+RCEE
Sbjct: 1   MGSMFRSEEVALVQLFLPTAAAYTCVSRLGELGLVEFRDLNASVSAFQRRFVVDVRRCEE 60

Query: 61  LERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKLRK 120
           LE+   +L +E+ RA + LP  +   PAPP + +L +QE+ ++L  ELR+V  N++ LR 
Sbjct: 61  LEKTFTFLQEEVRRAGLVLPPPKGRLPAPPPRDLLRIQEETERLAQELRDVRGNQQALRA 120

Query: 121 NLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQRLGAKLGFVSGLI 180
            L +L  +  +LR            +   E  P L++              ++ FV+G +
Sbjct: 121 QLHQLQLHAAVLRQGHEPQLAAAHTDGASERTPLLQAPG------GPHQDLRVNFVAGAV 174

Query: 181 NQGKVEAFEKMLWRVCKGYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVKK 240
              K  A E++LWR C+G+ I S+ EL++ LE P TGE   W  FLIS+WGEQIG K++K
Sbjct: 175 EPHKAPALERLLWRACRGFLIASFRELEQPLEHPVTGEPATWMTFLISYWGEQIGQKIRK 234

Query: 241 ICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRVI 300
           I DC+HCHV+P+    E R    + L  + Q+L  VL +TE +L QVL +  + +    +
Sbjct: 235 ITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFLSQVLGRVLQLLPPGQV 294

Query: 301 QVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEEGSRESGATIPSFMNII 360
           QV KMKA+Y  LN CS   T+KCLIAE WC   DL  L+ AL + S E G  + +  + I
Sbjct: 295 QVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRDSSMEEG--VSAVAHRI 352

Query: 361 PTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFAVMFGDFGHGFV 420
           P ++ PPT IRTN+FT  FQ IVDAYGVG Y+EVNPA +TIITFPFLFAVMFGD GHG +
Sbjct: 353 PCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITFPFLFAVMFGDVGHGLL 412

Query: 421 MFLFALLLVLNENHPRLNQSQ-EIMRMFFNGRYILLLMGLFSVYTGLIYNDCFSKSVNLF 479
           MFLFAL +VL EN P +  +Q EI + FF GRY+LLLMGLFS+YTG IYN+CFS++ ++F
Sbjct: 413 MFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIYTGFIYNECFSRATSIF 472

Query: 480 GSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPGVFRGPYPLGIDPIWNL 539
            SGW+V+AM + S           W+D+ +  +++L LDP++ GVF GPYP GIDPIW+L
Sbjct: 473 PSGWSVAAMANQSG----------WSDAFLAQHTMLTLDPNVTGVFLGPYPFGIDPIWSL 522

Query: 540 ATNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLCIFG 599
           A N L+FLNSFKMKMSVILG++HM FGV+LG+FNH+HF ++  + L ++PEL F+L +FG
Sbjct: 523 AANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTFLLGLFG 582

Query: 600 YLIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSG-LYTGQEYVQRVLLVVTAL 658
           YL+F++ YKWL   A  +  APSILI FINMFLF  S ++  LY  QE VQ  L+V+   
Sbjct: 583 YLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQATLVVLALA 642

Query: 659 SVPVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLLGSQDIE----EGNHQV 714
            VP+L LG PL LL  H         R       +  E +  LL   D        + + 
Sbjct: 643 MVPILLLGTPLHLLHRHR-------RRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEK 695

Query: 715 EDGCREMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWALSLAHAQLSDVLWAML 774
             G  +    E    E+LM Q IH+IE+CLGC+SNTASYLRLWALSLAHAQLS+VLWAM+
Sbjct: 696 AGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMV 755

Query: 775 MRVGLRVDTTYGV--LLLLPVIALFAVLTIFILLIMEGLSAFLHAIRLHWVEFQNKFYVG 832
           MR+GL +    GV  ++L+P+ A FAV+T+ ILL+MEGLSAFLHA+RLHWVEFQNKFY G
Sbjct: 756 MRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSG 815

Query: 833 AGTKFVPFSFS 843
            G K  PF+F+
Sbjct: 816 TGYKLSPFTFA 826


>gi|5174717 T-cell, immune regulator 1 isoform b [Homo sapiens]
          Length = 614

 Score =  652 bits (1681), Expect = 0.0
 Identities = 335/627 (53%), Positives = 431/627 (68%), Gaps = 27/627 (4%)

Query: 225 FLISFWGEQIGHKVKKICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYL 284
           FLIS+WGEQIG K++KI DC+HCHV+P+    E R    + L  + Q+L  VL +TE +L
Sbjct: 3   FLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFL 62

Query: 285 RQVLCKAAESVYSRVIQVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEE 344
            QVL +  + +    +QV KMKA+Y  LN CS   T+KCLIAE WC   DL  L+ AL +
Sbjct: 63  SQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRD 122

Query: 345 GSRESGATIPSFMNIIPTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITF 404
            S E G  + +  + IP ++ PPT IRTN+FT  FQ IVDAYGVG Y+EVNPA +TIITF
Sbjct: 123 SSMEEG--VSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180

Query: 405 PFLFAVMFGDFGHGFVMFLFALLLVLNENHPRLNQSQ-EIMRMFFNGRYILLLMGLFSVY 463
           PFLFAVMFGD GHG +MFLFAL +VL EN P +  +Q EI + FF GRY+LLLMGLFS+Y
Sbjct: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240

Query: 464 TGLIYNDCFSKSVNLFGSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPG 523
           TG IYN+CFS++ ++F SGW+V+AM + S           W+D+ +  +++L LDP++ G
Sbjct: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSG----------WSDAFLAQHTMLTLDPNVTG 290

Query: 524 VFRGPYPLGIDPIWNLATNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNI 583
           VF GPYP GIDPIW+LA N L+FLNSFKMKMSVILG++HM FGV+LG+FNH+HF ++  +
Sbjct: 291 VFLGPYPFGIDPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRL 350

Query: 584 YLVSIPELLFMLCIFGYLIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSG-LY 642
            L ++PEL F+L +FGYL+F++ YKWL   A  +  APSILI FINMFLF  S ++  LY
Sbjct: 351 LLETLPELTFLLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLY 410

Query: 643 TGQEYVQRVLLVVTALSVPVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLL 702
             QE VQ  L+V+    VP+L LG PL LL  H         R       +  E +  LL
Sbjct: 411 PRQEVVQATLVVLALAMVPILLLGTPLHLLHRHR-------RRLRRRPADRQEENKAGLL 463

Query: 703 GSQDIE----EGNHQVEDGCREMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWA 758
              D        + +   G  +    E    E+LM Q IH+IE+CLGC+SNTASYLRLWA
Sbjct: 464 DLPDASVNGWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWA 523

Query: 759 LSLAHAQLSDVLWAMLMRVGLRVDTTYGV--LLLLPVIALFAVLTIFILLIMEGLSAFLH 816
           LSLAHAQLS+VLWAM+MR+GL +    GV  ++L+P+ A FAV+T+ ILL+MEGLSAFLH
Sbjct: 524 LSLAHAQLSEVLWAMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLH 583

Query: 817 AIRLHWVEFQNKFYVGAGTKFVPFSFS 843
           A+RLHWVEFQNKFY G G K  PF+F+
Sbjct: 584 ALRLHWVEFQNKFYSGTGYKLSPFTFA 610


>gi|45505178 cancer antigen 1 [Homo sapiens]
          Length = 641

 Score = 37.0 bits (84), Expect = 0.078
 Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 18/152 (11%)

Query: 6   RSETMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELERIL 65
           R++   L   F +    Y CL    E+ + + +  N++VS +        K+ EE+ER L
Sbjct: 264 RNDKEMLQLQFKKIKANYVCLQ---ERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVER-L 319

Query: 66  VYLVQEINRA-----DIPLPEGEASPPAPPLKQVLEMQEQLQKLEVE-LREVTKNKEKLR 119
             L +E+ +A     D+   E EA       ++ L +QE+ QKLE E L E  K K +L 
Sbjct: 320 QQLKKELEKATASALDLLKREKEAQE-----QEFLSLQEEFQKLEKENLEERQKLKSRLE 374

Query: 120 KNLLELIEYTHMLRVTKTFVKRNVEFEPTYEE 151
           K L ++     M    +T   +N++ +    E
Sbjct: 375 KLLTQVRNLQFMSENERT---KNIKLQQQINE 403


>gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 2 [Homo sapiens]
          Length = 595

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 47/212 (22%), Positives = 94/212 (44%), Gaps = 20/212 (9%)

Query: 40  LNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVLE-MQ 98
           ++Q + + +++   +++R EELER L  L    N+   PLP     PPA P +  L+ ++
Sbjct: 251 MSQEICTLKKEKQQDMRRVEELERSLSKLK---NQMAEPLP---PEPPAVPSEVELQHLR 304

Query: 99  EQLQKLEVELREVTKN-----------KEKLRKNLLELIEYTHMLRVTKTFVKRNVEFEP 147
           ++L+++  EL+   KN           +E++R+    L +    L+     +++  + + 
Sbjct: 305 KELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQS 364

Query: 148 TYEEFPSLESDSLLDYSCMQRLGAKLGFVSGLINQGKVEAFEKMLWRVCKGYTIVSYAEL 207
            +EE  +    +L     ++ L  KLG V       + E  E        G    S + +
Sbjct: 365 VFEELNNENKSTLQLEQQVKELQEKLGEVKETETSAQKEP-EAARGPGAPGPGGESSSFM 423

Query: 208 DESLEDPETGEVI-KWYVFLISFWGEQIGHKV 238
           D   E  +  E++ K  +  I +W E+   K+
Sbjct: 424 DHLKEKADLSELVKKQELRFIQYWQERCHQKI 455


>gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 2 [Homo sapiens]
          Length = 595

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 47/212 (22%), Positives = 94/212 (44%), Gaps = 20/212 (9%)

Query: 40  LNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVLE-MQ 98
           ++Q + + +++   +++R EELER L  L    N+   PLP     PPA P +  L+ ++
Sbjct: 251 MSQEICTLKKEKQQDMRRVEELERSLSKLK---NQMAEPLP---PEPPAVPSEVELQHLR 304

Query: 99  EQLQKLEVELREVTKN-----------KEKLRKNLLELIEYTHMLRVTKTFVKRNVEFEP 147
           ++L+++  EL+   KN           +E++R+    L +    L+     +++  + + 
Sbjct: 305 KELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQS 364

Query: 148 TYEEFPSLESDSLLDYSCMQRLGAKLGFVSGLINQGKVEAFEKMLWRVCKGYTIVSYAEL 207
            +EE  +    +L     ++ L  KLG V       + E  E        G    S + +
Sbjct: 365 VFEELNNENKSTLQLEQQVKELQEKLGEVKETETSAQKEP-EAARGPGAPGPGGESSSFM 423

Query: 208 DESLEDPETGEVI-KWYVFLISFWGEQIGHKV 238
           D   E  +  E++ K  +  I +W E+   K+
Sbjct: 424 DHLKEKADLSELVKKQELRFIQYWQERCHQKI 455


>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform a [Homo sapiens]
          Length = 6620

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 4/84 (4%)

Query: 42   QNVSSFQRKFVGEVKRCEELERILVYLVQEINR--ADIPLPEGEAS-PPAPPLKQVLEMQ 98
            +N ++F++     V R +    ++   +QE  +  A+  L  G+ S PP PPL+  LE  
Sbjct: 5773 KNQAAFEQYLEFLVGRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQP 5832

Query: 99   -EQLQKLEVELREVTKNKEKLRKN 121
             E++Q+ +  L+E+ +NK + R+N
Sbjct: 5833 VERVQRYQALLKELIRNKARNRQN 5856


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 4/84 (4%)

Query: 42   QNVSSFQRKFVGEVKRCEELERILVYLVQEINR--ADIPLPEGEAS-PPAPPLKQVLEMQ 98
            +N ++F++     V R +    ++   +QE  +  A+  L  G+ S PP PPL+  LE  
Sbjct: 5773 KNQAAFEQYLEFLVGRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQP 5832

Query: 99   -EQLQKLEVELREVTKNKEKLRKN 121
             E++Q+ +  L+E+ +NK + R+N
Sbjct: 5833 VERVQRYQALLKELIRNKARNRQN 5856


>gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 2 [Homo sapiens]
          Length = 602

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 49/217 (22%), Positives = 99/217 (45%), Gaps = 22/217 (10%)

Query: 36  QFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVL 95
           + R ++Q + + +++   +++R E+LER L  L    N+   PLP     PPA P +  L
Sbjct: 254 RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLK---NQMAEPLP---PEPPAVPSEVEL 307

Query: 96  E-MQEQLQKLEVELREVTKN-----------KEKLRKNLLELIEYTHMLRVTKTFVKRNV 143
           + ++++L+++  EL+   KN           +E++R+    L +    ++     +++  
Sbjct: 308 QHLRKELERVAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQEERIQEQHKSLQQLA 367

Query: 144 EFEPTYEEFPSLESDSLLDY-SCMQRLGAKLGFVSGLINQGKVEAFEKMLWRVCKGYTIV 202
           + +  +EE P+ E+ S L     ++ L  KLG V       + E  E        G    
Sbjct: 368 KPQSVFEE-PNNENKSTLQLEQQVKELQEKLGEVKESETSAQKEP-EAARGPAAPGPGGE 425

Query: 203 SYAELDESLEDPETGEVI-KWYVFLISFWGEQIGHKV 238
           S + +D   E  +  E++ K  +  I +W E+   K+
Sbjct: 426 SSSFMDHLEEKADLSELVKKQELRFIQYWQERCHQKI 462


>gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 595

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 47/210 (22%), Positives = 92/210 (43%), Gaps = 20/210 (9%)

Query: 42  QNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVLE-MQEQ 100
           Q + + +++   +++R EELER L  L    N+   PLP     PPA P +  L+ ++++
Sbjct: 253 QEICTLKKEKQQDMRRVEELERSLSKLK---NQMAEPLP---PEPPAVPSEVELQHLRKE 306

Query: 101 LQKLEVELREVTKN-----------KEKLRKNLLELIEYTHMLRVTKTFVKRNVEFEPTY 149
           L+++  EL+   KN           +E++R+    L +    L+     +++  + +  +
Sbjct: 307 LERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVF 366

Query: 150 EEFPSLESDSLLDYSCMQRLGAKLGFVSGLINQGKVEAFEKMLWRVCKGYTIVSYAELDE 209
           EE  +    +L     ++ L  KLG V       + E  E        G    S + +D 
Sbjct: 367 EELNNENKSTLQLEQQVKELQEKLGEVKETETSAQKEP-EAARGPGAPGPGGESSSFMDH 425

Query: 210 SLEDPETGEVI-KWYVFLISFWGEQIGHKV 238
             E  +  E++ K  +  I +W E+   K+
Sbjct: 426 LKEKADLSELVKKQELRFIQYWQERCHQKI 455


>gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein 3
           [Homo sapiens]
          Length = 580

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 23/84 (27%), Positives = 49/84 (58%), Gaps = 7/84 (8%)

Query: 36  QFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVL 95
           + R ++Q + + +++   +++R E+LER L  L    N+   PLP     PPA P +  L
Sbjct: 226 RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLK---NQMAEPLP---PEPPAVPSEVEL 279

Query: 96  E-MQEQLQKLEVELREVTKNKEKL 118
           + ++++L+++  EL+   KN +++
Sbjct: 280 QHLRKELERVAGELQAQVKNNQRI 303


>gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein 3
           isoform 2 [Homo sapiens]
          Length = 602

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 23/84 (27%), Positives = 49/84 (58%), Gaps = 7/84 (8%)

Query: 36  QFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVL 95
           + R ++Q + + +++   +++R E+LER L  L    N+   PLP     PPA P +  L
Sbjct: 254 RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLK---NQMAEPLP---PEPPAVPSEVEL 307

Query: 96  E-MQEQLQKLEVELREVTKNKEKL 118
           + ++++L+++  EL+   KN +++
Sbjct: 308 QHLRKELERVAGELQAQVKNNQRI 331


>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
           isoform 1 [Homo sapiens]
          Length = 632

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 23/84 (27%), Positives = 49/84 (58%), Gaps = 7/84 (8%)

Query: 36  QFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVL 95
           + R ++Q + + +++   +++R E+LER L  L    N+   PLP     PPA P +  L
Sbjct: 255 RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLK---NQMAEPLP---PEPPAVPSEVEL 308

Query: 96  E-MQEQLQKLEVELREVTKNKEKL 118
           + ++++L+++  EL+   KN +++
Sbjct: 309 QHLRKELERVAGELQAQVKNNQRI 332


>gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 632

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 23/84 (27%), Positives = 49/84 (58%), Gaps = 7/84 (8%)

Query: 36  QFRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVL 95
           + R ++Q + + +++   +++R E+LER L  L    N+   PLP     PPA P +  L
Sbjct: 255 RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLK---NQMAEPLP---PEPPAVPSEVEL 308

Query: 96  E-MQEQLQKLEVELREVTKNKEKL 118
           + ++++L+++  EL+   KN +++
Sbjct: 309 QHLRKELERVAGELQAQVKNNQRI 332


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 19/158 (12%)

Query: 59   EELERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKL 118
            E+ + +L  L+Q I           A    P  +++  M+E+  KL   L++V KNKE +
Sbjct: 3522 EKQQLLLTLLLQRIRSIQNVPESSGAVETVPAFQEITSMKERCNKL---LQKVQKNKELV 3578

Query: 119  RKNLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQRLGAKLGFVSG 178
            +  + E   +T  +   K F      F+ T   F ++      + S       +   +  
Sbjct: 3579 QTEIQERHSFTKEIIALKNF------FQQTTTSFQNMAFQDHPEKS------EQFEELQS 3626

Query: 179  LINQGKV---EAFEKMLWRVCKGYTIVSYAELDESLED 213
            ++ +GK+      EK+  +  + YTIV  AE++  +E+
Sbjct: 3627 ILKKGKLTFENIMEKLRIKYSEMYTIVP-AEIESQVEE 3663


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 35.0 bits (79), Expect = 0.30
 Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 19/158 (12%)

Query: 59   EELERILVYLVQEINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELREVTKNKEKL 118
            E+ + +L  L+Q I           A    P  +++  M+E+  KL   L++V KNKE +
Sbjct: 3522 EKQQLLLTLLLQRIRSIQNVPESSGAVETVPAFQEITSMKERCNKL---LQKVQKNKELV 3578

Query: 119  RKNLLELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESDSLLDYSCMQRLGAKLGFVSG 178
            +  + E   +T  +   K F      F+ T   F ++      + S       +   +  
Sbjct: 3579 QTEIQERHSFTKEIIALKNF------FQQTTTSFQNMAFQDHPEKS------EQFEELQS 3626

Query: 179  LINQGKV---EAFEKMLWRVCKGYTIVSYAELDESLED 213
            ++ +GK+      EK+  +  + YTIV  AE++  +E+
Sbjct: 3627 ILKKGKLTFENIMEKLRIKYSEMYTIVP-AEIESQVEE 3663


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 34.7 bits (78), Expect = 0.39
 Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 38   RDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEAS---PPAPPLKQV 94
            ++L Q +S    +     KR  ELE+I   + QE +     L E EAS        L+  
Sbjct: 1507 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQ 1566

Query: 95   LEMQEQLQKLEVELREVTKNKEKLRKNLLELIE 127
            LE+ +   +++ ++ E  +  +++++N + ++E
Sbjct: 1567 LELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVE 1599


>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 632

 Score = 34.3 bits (77), Expect = 0.51
 Identities = 34/147 (23%), Positives = 71/147 (48%), Gaps = 18/147 (12%)

Query: 40  LNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVLE-MQ 98
           ++Q + + +++   +++R EELER L  L    N+   PLP     PPA P +  L+ ++
Sbjct: 259 MSQEICTLKKEKQQDMRRVEELERSLSKLK---NQMAEPLP---PEPPAVPSEVELQHLR 312

Query: 99  EQLQKLEVELREVTKN-----------KEKLRKNLLELIEYTHMLRVTKTFVKRNVEFEP 147
           ++L+++  EL+   KN           +E++R+    L +    L+     +++  + + 
Sbjct: 313 KELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQS 372

Query: 148 TYEEFPSLESDSLLDYSCMQRLGAKLG 174
            +EE  +    +L     ++ L  KLG
Sbjct: 373 VFEELNNENKSTLQLEQQVKELQEKLG 399


>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 2 isoform 3 [Homo sapiens]
          Length = 632

 Score = 34.3 bits (77), Expect = 0.51
 Identities = 34/147 (23%), Positives = 71/147 (48%), Gaps = 18/147 (12%)

Query: 40  LNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEASPPAPPLKQVLE-MQ 98
           ++Q + + +++   +++R EELER L  L    N+   PLP     PPA P +  L+ ++
Sbjct: 259 MSQEICTLKKEKQQDMRRVEELERSLSKLK---NQMAEPLP---PEPPAVPSEVELQHLR 312

Query: 99  EQLQKLEVELREVTKN-----------KEKLRKNLLELIEYTHMLRVTKTFVKRNVEFEP 147
           ++L+++  EL+   KN           +E++R+    L +    L+     +++  + + 
Sbjct: 313 KELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQS 372

Query: 148 TYEEFPSLESDSLLDYSCMQRLGAKLG 174
            +EE  +    +L     ++ L  KLG
Sbjct: 373 VFEELNNENKSTLQLEQQVKELQEKLG 399


>gi|50083279 centrosome protein 4 [Homo sapiens]
          Length = 1140

 Score = 34.3 bits (77), Expect = 0.51
 Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 5/122 (4%)

Query: 43  NVSSFQRKFVGEVKRCEELERILVYLVQEI-NRADIPLPEGEASPPAPPLKQVLEMQEQL 101
           N+S+   K   E+   ++L + L    +E+   AD  L E +       L ++ +++E +
Sbjct: 307 NLSNKNEKLCQELTEIDQLAQQLERHKEEVLETADKELGEAKKEIKRK-LSEMQDLEETM 365

Query: 102 QKLEVELREVTKNKEKLRKNLL---ELIEYTHMLRVTKTFVKRNVEFEPTYEEFPSLESD 158
            KL++EL    K KE+L   LL   +L    H L   K  + + VE     E   +LE +
Sbjct: 366 AKLQLELNLCQKEKERLSDELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVE 425

Query: 159 SL 160
            +
Sbjct: 426 RM 427


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 33.9 bits (76), Expect = 0.66
 Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 38   RDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEAS---PPAPPLKQV 94
            ++L Q +S    +     KR  ELE+I   + QE       L E EAS        L+  
Sbjct: 1509 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQ 1568

Query: 95   LEMQEQLQKLEVELREVTKNKEKLRKNLLELIE 127
            LE+ +   +++ ++ E  +  ++L++N + ++E
Sbjct: 1569 LELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVE 1601


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 33.9 bits (76), Expect = 0.66
 Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 38   RDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLPEGEAS---PPAPPLKQV 94
            ++L Q +S    +     KR  ELE+I   + QE       L E EAS        L+  
Sbjct: 1509 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQ 1568

Query: 95   LEMQEQLQKLEVELREVTKNKEKLRKNLLELIE 127
            LE+ +   +++ ++ E  +  ++L++N + ++E
Sbjct: 1569 LELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVE 1601


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 33.9 bits (76), Expect = 0.66
 Identities = 27/116 (23%), Positives = 56/116 (48%), Gaps = 12/116 (10%)

Query: 7   SETMCLAQLFLQSGTAYEC---LSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELER 63
           +E + L Q  LQ+    +C   L++  ++ L Q++++     ++Q+K V   ++C  L+ 
Sbjct: 791 AEQLSLVQAELQTQWEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLVQLQEKCLALQA 850

Query: 64  ILVYLVQ---------EINRADIPLPEGEASPPAPPLKQVLEMQEQLQKLEVELRE 110
            +  L +         E N++ +   E  AS P+  +K+++    Q  + E EL E
Sbjct: 851 QITALTKQNEQHIKELEKNKSQMSGVEAAASDPSEKVKKIMNQVFQSLRREFELEE 906


>gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 [Homo sapiens]
          Length = 602

 Score = 33.5 bits (75), Expect = 0.86
 Identities = 28/99 (28%), Positives = 54/99 (54%), Gaps = 10/99 (10%)

Query: 24  ECLSAL-GEKGLVQ--FRDLNQNVSSFQRKFVGEVKRCEELERILVYLVQEINRADIPLP 80
           EC   L GE+   Q   R ++Q + + +++   +++R E+LER L  L    N+   PLP
Sbjct: 239 ECAEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLK---NQMAEPLP 295

Query: 81  EGEASPPAPPLKQVLE-MQEQLQKLEVELREVTKNKEKL 118
                PPA P +  L+ ++++L+++  EL+   K  +++
Sbjct: 296 ---PEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRI 331


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.140    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,197,998
Number of Sequences: 37866
Number of extensions: 1392668
Number of successful extensions: 6697
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 6460
Number of HSP's gapped (non-prelim): 274
length of query: 856
length of database: 18,247,518
effective HSP length: 111
effective length of query: 745
effective length of database: 14,044,392
effective search space: 10463072040
effective search space used: 10463072040
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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