Search of human proteins with 12667788

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo
sapiens]
         (1960 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]   3790   0.0  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]  3013   0.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...  2954   0.0  
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...  2951   0.0  
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...  2940   0.0  
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...  2937   0.0  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]         2539   0.0  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]         2536   0.0  
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]         2519   0.0  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...  1428   0.0  
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...  1410   0.0  
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...  1410   0.0  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...  1410   0.0  
gi|156104908 myosin heavy chain 6 [Homo sapiens]                     1406   0.0  
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...  1405   0.0  
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...  1402   0.0  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...  1397   0.0  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...  1374   0.0  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...  1370   0.0  
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]             1236   0.0  
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       590   e-168
gi|153945715 myosin VC [Homo sapiens]                                 588   e-167
gi|42794779 myosin 18A isoform b [Homo sapiens]                       588   e-167
gi|28416946 myosin 18A isoform a [Homo sapiens]                       588   e-167
gi|122937345 myosin VB [Homo sapiens]                                 587   e-167
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       585   e-166
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     504   e-142
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     504   e-142
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     504   e-142
gi|154354979 myosin X [Homo sapiens]                                  496   e-139

>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 3790 bits (9828), Expect = 0.0
 Identities = 1960/1960 (100%), Positives = 1960/1960 (100%)

Query: 1    MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVE 60
            MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVE
Sbjct: 1    MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVE 60

Query: 61   NGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVV 120
            NGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVV
Sbjct: 61   NGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVV 120

Query: 121  INPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGK 180
            INPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGK
Sbjct: 121  INPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGK 180

Query: 181  TENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIR 240
            TENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIR
Sbjct: 181  TENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIR 240

Query: 241  INFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKY 300
            INFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKY
Sbjct: 241  INFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKY 300

Query: 301  RFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNT 360
            RFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNT
Sbjct: 301  RFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNT 360

Query: 361  DQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKA 420
            DQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKA
Sbjct: 361  DQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKA 420

Query: 421  TYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLF 480
            TYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLF
Sbjct: 421  TYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLF 480

Query: 481  NHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDK 540
            NHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDK
Sbjct: 481  NHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDK 540

Query: 541  SFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLL 600
            SFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLL
Sbjct: 541  SFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLL 600

Query: 601  HQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMAT 660
            HQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMAT
Sbjct: 601  HQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMAT 660

Query: 661  LRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQR 720
            LRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQR
Sbjct: 661  LRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQR 720

Query: 721  YEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKIT 780
            YEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKIT
Sbjct: 721  YEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKIT 780

Query: 781  DVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQV 840
            DVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQV
Sbjct: 781  DVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQV 840

Query: 841  SRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE 900
            SRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE
Sbjct: 841  SRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE 900

Query: 901  ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
            ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ
Sbjct: 901  ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960

Query: 961  KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK 1020
            KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK
Sbjct: 961  KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK 1020

Query: 1021 LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 1080
            LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK
Sbjct: 1021 LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 1080

Query: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
            KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE
Sbjct: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140

Query: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1200
            LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1200

Query: 1201 LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK 1260
            LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK
Sbjct: 1201 LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK 1260

Query: 1261 FNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEE 1320
            FNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEE
Sbjct: 1261 FNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEE 1320

Query: 1321 NRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL 1380
            NRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL
Sbjct: 1321 NRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL 1380

Query: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLE 1440
            ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLE
Sbjct: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLE 1440

Query: 1441 KKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNK 1500
            KKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNK
Sbjct: 1441 KKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNK 1500

Query: 1501 QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV 1560
            QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV
Sbjct: 1501 QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV 1560

Query: 1561 NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLK 1620
            NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLK
Sbjct: 1561 NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLK 1620

Query: 1621 DLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEA 1680
            DLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEA
Sbjct: 1621 DLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEA 1680

Query: 1681 EMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEE 1740
            EMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEE
Sbjct: 1681 EMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEE 1740

Query: 1741 EQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGT 1800
            EQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGT
Sbjct: 1741 EQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGT 1800

Query: 1801 VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ 1860
            VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ
Sbjct: 1801 VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ 1860

Query: 1861 YKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK 1920
            YKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK
Sbjct: 1861 YKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK 1920

Query: 1921 LRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPAE 1960
            LRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPAE
Sbjct: 1921 LRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPAE 1960


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 3013 bits (7811), Expect = 0.0
 Identities = 1533/1965 (78%), Positives = 1743/1965 (88%), Gaps = 12/1965 (0%)

Query: 7    DKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVK 66
            ++YL+VD+  I NP  QADW AKKLVW+PS++ GFE AS+KEE G+E +VEL ENGKK  
Sbjct: 11   ERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAM 70

Query: 67   VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKN 126
            VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLK+RYYSGLIYTYSGLFCVVINPYKN
Sbjct: 71   VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKN 130

Query: 127  LPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKK 186
            LPIYSE I+EMY+GKKRHEMPPHIYAI+++AYR M+QDREDQSILCTGESGAGKTENTKK
Sbjct: 131  LPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKK 190

Query: 187  VIQYLAYVASSHKSKKDQ---GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 243
            VIQYLA+VASSHK +KD    GELERQLLQANPILE+FGNAKTVKNDNSSRFGKFIRINF
Sbjct: 191  VIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINF 250

Query: 244  DVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFL 303
            DV GYIVGANIETYLLEKSRA+RQAK+ERTFHIFY LLSGAGEHLK+DLLLE +N YRFL
Sbjct: 251  DVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFL 310

Query: 304  SNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQA 363
            SNG++ IPGQQDKD FQETMEAM IMG   EE + +L+V+S VLQ GNI FKKERNTDQA
Sbjct: 311  SNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQA 370

Query: 364  SMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYE 423
            SMP+NT AQK+ HLLG+NV +FTR ILTPRIKVGRDYVQKAQTKEQADFA+EALAKATYE
Sbjct: 371  SMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYE 430

Query: 424  RMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHT 483
            R+FRWLV RINKALD+TKRQGASFIGILDIAGFEIF+LNSFEQLCINYTNEKLQQLFNHT
Sbjct: 431  RLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHT 490

Query: 484  MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFV 543
            MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIE+PA PPG+LALLDEECWFPKATDK+FV
Sbjct: 491  MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFV 550

Query: 544  EKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQS 603
            EK++QEQG+H KFQKP+QLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDN+ATLLHQS
Sbjct: 551  EKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQS 610

Query: 604  SDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRN 663
            SD+FV+ELWKDVDRI+GLDQV GM+ETA   A+KT+KGMFRTVGQLYKE L KLMATLRN
Sbjct: 611  SDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRN 670

Query: 664  TNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEI 723
            TNPNFVRCIIPNHEK+AGKLDPHLVLDQLRCNGVLEGIRICRQGFPNR+VFQEFRQRYEI
Sbjct: 671  TNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 730

Query: 724  LTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVI 783
            LTPN+IPKGFMDGKQAC  MI+ALELD NLYRIGQSK+FFRAGVLAHLEEERDLKITD+I
Sbjct: 731  LTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDII 790

Query: 784  IGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQ 843
            I FQA CRGYLARKAFAK+QQQL+A+KVLQRNCAAYLKLR+WQWWR+FTKVKPLLQV+RQ
Sbjct: 791  IFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQ 850

Query: 844  EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
            EEE+ AK+EEL+KV+EKQ   E  L EME    QL+ EK  L EQLQAETEL AEAEE+R
Sbjct: 851  EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910

Query: 904  ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
            ARL AKKQELEEI HDLE+RVEEEEER Q LQ EKKKMQ +IQ+LEEQL+EEE ARQKLQ
Sbjct: 911  ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970

Query: 964  LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKN 1023
            LEKVT EAK+KK+EEE ++LEDQN K  KEKKL+EDRIAE ++ L EEEEK+K+LAK++N
Sbjct: 971  LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030

Query: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
            K E MI+DLEERL++EEK RQELEK +RKL+G++TDL DQIAELQAQI ELK+QLAKKEE
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090

Query: 1084 ELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEA 1143
            ELQ ALAR ++E   KN ALK +REL++QI+ELQED ESE+ASRNKAEKQKRDL EELEA
Sbjct: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEA 1150

Query: 1144 LKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAE 1203
            LKTELEDTLD+TAAQQELR+KREQEV  LKK LEEE K HEAQIQ+MRQ+H+ A+EEL+E
Sbjct: 1151 LKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSE 1210

Query: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263
            QLEQ KR KANLEK KQ LE +  ELA EVKVL Q K +SEHKRKK++AQ+QEL  K +E
Sbjct: 1211 QLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSE 1270

Query: 1264 GERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ 1323
            G+R+R ELA+K +KLQ ELDNV+ LL +++ K  K  KD ++LESQLQDTQELLQEE RQ
Sbjct: 1271 GDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQ 1330

Query: 1324 KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETA 1383
            KL+LS++++Q+E+EKNS +EQ EEEEEA+ NLEKQ+  L +Q+AD KKK++D +G +E+ 
Sbjct: 1331 KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESL 1390

Query: 1384 EEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ 1443
            EE K+KL KD E LSQR EEK  AYDKLEKTK RLQQELDDL VDLDHQRQ A NLEKKQ
Sbjct: 1391 EEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ 1450

Query: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFR 1503
            KKFDQLLAEEK+ISA+YAEERDRAEAEAREKETKALSLARALEEA+E K E ER NKQ R
Sbjct: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLR 1510

Query: 1504 TEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQ 1563
             +MEDLMSSKDDVGK+VHELEKSKRALEQQVEEM+TQLEELEDELQATEDAKLRLEVN+Q
Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQ 1570

Query: 1564 AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
            AMKAQFERDLQ RDEQ+EEKK+ L++QVRE+EAELEDERKQR++AVA++KK+E+DLKDLE
Sbjct: 1571 AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE 1630

Query: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
            A I++ANK RDE IKQLRKLQAQMKD  REL++ RASR+EI AQ+KE+EKKLKS+EAE++
Sbjct: 1631 AQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEIL 1690

Query: 1684 QLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALEEKRRLEARIAQLEEELEEEQ 1742
            QLQEELA++ERA+R A+QERDELADEI NS SGK AL L+EKRRLEARIAQLEEELEEEQ
Sbjct: 1691 QLQEELASSERARRHAEQERDELADEITNSASGKSAL-LDEKRRLEARIAQLEEELEEEQ 1749

Query: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
             N EL+NDR +K  LQ+D +N +L  ERS AQK++NARQQLERQNKELK KLQE+EG VK
Sbjct: 1750 SNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVK 1809

Query: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862
            SK+KA+I+ALEAKI QLEEQL+ E KER AA K VRRTEKKLK++ +QV+DERR+A+QYK
Sbjct: 1810 SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYK 1869

Query: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            +Q +KA+ R+KQLKRQLEEAEEEA RANASRRKLQREL+DATE  + ++REVS+LKN+LR
Sbjct: 1870 EQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929

Query: 1923 RGDLPFVVPRRMARK-----GAG-DGSDEEVDGK-ADGAEAKPAE 1960
            RG        R  R+     GA  + SD++ + K +D  E +P +
Sbjct: 1930 RGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQ 1974


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 2954 bits (7657), Expect = 0.0
 Identities = 1496/1965 (76%), Positives = 1737/1965 (88%), Gaps = 14/1965 (0%)

Query: 7    DKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVK 66
            +K+L+VDKNFIN+P+AQADWAAK+LVWVPS+K GFE AS+KEE G+E +VELVENGKKV 
Sbjct: 11   EKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVT 70

Query: 67   VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKN 126
            V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL+ERY+SGLIYTYSGLFCVV+NPYK+
Sbjct: 71   VGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKH 130

Query: 127  LPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKK 186
            LPIYSE+IV+MYKGKKRHEMPPHIYAI DTAYRSM+QDREDQSILCTGESGAGKTENTKK
Sbjct: 131  LPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKK 190

Query: 187  VIQYLAYVASSHKSKKDQ---GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 243
            VIQYLA VASSHK KKD    GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF
Sbjct: 191  VIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 250

Query: 244  DVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFL 303
            DV GYIVGANIETYLLEKSRAIRQA++ERTFHIFYY+++GA E +++DLLLE +N Y FL
Sbjct: 251  DVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFL 310

Query: 304  SNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQA 363
            SNG V IP  QD +MFQET+EAM IMG  EEEQ+ +L+V+S VLQLGNIVFKKERNTDQA
Sbjct: 311  SNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQA 370

Query: 364  SMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYE 423
            SMPDNTAAQKV HL+GINVTDFTR ILTPRIKVGRD VQKAQTKEQADFA+EALAKATYE
Sbjct: 371  SMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYE 430

Query: 424  RMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHT 483
            R+FRW++ R+NKALDKT RQGASF+GILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHT
Sbjct: 431  RLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHT 490

Query: 484  MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFV 543
            MFILEQEEYQREGIEWNFIDFGLDLQPCI+LIE+P  PPG+LALLDEECWFPKATDKSFV
Sbjct: 491  MFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFV 550

Query: 544  EKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQS 603
            EK+  EQG+HPKFQKPKQLKDK +F IIHYAGKVDY A  WL KNMDPLNDN+ +LL+ S
Sbjct: 551  EKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNAS 610

Query: 604  SDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRN 663
            SDKFV++LWKDVDRI+GLDQ+A M+E++LP A KT+KGMFRTVGQLYKEQL KLM TLRN
Sbjct: 611  SDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRN 670

Query: 664  TNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEI 723
            T PNFVRCIIPNHEK++GKLD  LVL+QLRCNGVLEGIRICRQGFPNR+VFQEFRQRYEI
Sbjct: 671  TTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 730

Query: 724  LTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVI 783
            L  N+IPKGFMDGKQAC+LMIKALELD NLYRIGQSK+FFR GVLAHLEEERDLKITDVI
Sbjct: 731  LAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVI 790

Query: 784  IGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQ 843
            + FQA CRGYLARKAFAKRQQQLTAMKV+QRNCAAYLKLRNWQWWRLFTKVKPLLQV+RQ
Sbjct: 791  MAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQ 850

Query: 844  EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
            EEEM AKE+EL K +E+Q  AEN L E+E   SQL  EK  LQEQLQAETEL AEAEE+R
Sbjct: 851  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910

Query: 904  ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
             RL AKKQELEEI H++EAR+EEEE+R Q LQAE+KKM Q + +LEEQLEEEE+ARQKLQ
Sbjct: 911  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970

Query: 964  LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKN 1023
            LEKVT EAK+KKLE+E ++++DQN KL+KE+KLLE+RI++ TTNL EEEEK+K+L KLKN
Sbjct: 971  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030

Query: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
            KHE+MI++LE RL++EEK RQELEK +RKLEGD++D  +QIA+LQAQIAELKMQLAKKEE
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090

Query: 1084 ELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEA 1143
            ELQAALAR+++E AQKN ALKKIRELE  IS+LQEDL+SERA+RNKAEKQKRDLGEELEA
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150

Query: 1144 LKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAE 1203
            LKTELEDTLDSTA QQELR+KREQEV +LKK L+EE ++HEAQ+QEMRQKH+QAVEEL E
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210

Query: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263
            QLEQ KR KANL+K KQTLE E  +LA E++VL Q K + EHK+KK+EAQ+QELQ K ++
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270

Query: 1264 GERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ 1323
            GER R EL DKV KLQ E+++VTG+L++++ K+ KL KD ++L SQLQDTQELLQEE RQ
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330

Query: 1324 KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETA 1383
            KL++STKL+Q+E+E+NS ++QL+EE EAK NLE+ I+TL+ Q++D KKK++D    +E  
Sbjct: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL 1390

Query: 1384 EEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ 1443
            EE K++ QK++E L+Q++EEK AAYDKLEKTK RLQQELDDL+VDLD+QRQ   NLEKKQ
Sbjct: 1391 EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450

Query: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFR 1503
            +KFDQLLAEEK IS+KYA+ERDRAEAEAREKETKALSLARALEEA+E K ELER NK  +
Sbjct: 1451 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1510

Query: 1504 TEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQ 1563
             EMEDL+SSKDDVGK+VHELEKSKRALE Q+EEMKTQLEELEDELQATEDAKLRLEVN+Q
Sbjct: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570

Query: 1564 AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
            A+K QFERDLQ RDEQ+EEK++QL RQ+ E E ELEDERKQR++A AA+KKLE DLKDLE
Sbjct: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630

Query: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
               DSA K R+EAIKQLRKLQAQMKD  REL+D RASR+EI A AKENEKK KS+EA+++
Sbjct: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1690

Query: 1684 QLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALEEKRRLEARIAQLEEELEEEQ 1742
            QLQE+LAAAERA++QA  E++ELA+E+A+S SG+ AL  +EKRRLEARIAQLEEELEEEQ
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ-DEKRRLEARIAQLEEELEEEQ 1749

Query: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
            GN E ++DR++KA  Q +Q++ +L  ERS AQKNE+ARQQLERQNKEL+ KL EMEG VK
Sbjct: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 1809

Query: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862
            SK+K++I ALEAKIAQLEEQ++ E +E+QAA K +++ +KKLK++LLQV+DER+ AEQYK
Sbjct: 1810 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYK 1869

Query: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            +QA+K + R+KQLKRQLEEAEEE+QR NA+RRKLQREL++ATE+ +AM REV++LK+KLR
Sbjct: 1870 EQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929

Query: 1923 RGDLPFVVPRRMARKGA------GDGSDEEVDGK-ADGAEAKPAE 1960
            RG+    VP R  R G        DGS+EE D + AD    K +E
Sbjct: 1930 RGNETSFVPSR--RSGGRRVIENADGSEEETDTRDADFNGTKASE 1972


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 2951 bits (7650), Expect = 0.0
 Identities = 1496/1972 (75%), Positives = 1737/1972 (88%), Gaps = 21/1972 (1%)

Query: 7    DKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVK 66
            +K+L+VDKNFIN+P+AQADWAAK+LVWVPS+K GFE AS+KEE G+E +VELVENGKKV 
Sbjct: 11   EKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVT 70

Query: 67   VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKN 126
            V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL+ERY+SGLIYTYSGLFCVV+NPYK+
Sbjct: 71   VGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKH 130

Query: 127  LPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKK 186
            LPIYSE+IV+MYKGKKRHEMPPHIYAI DTAYRSM+QDREDQSILCTGESGAGKTENTKK
Sbjct: 131  LPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKK 190

Query: 187  VIQYLAYVASSHKSKKDQ----------GELERQLLQANPILEAFGNAKTVKNDNSSRFG 236
            VIQYLA VASSHK KKD           GELE+QLLQANPILEAFGNAKTVKNDNSSRFG
Sbjct: 191  VIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFG 250

Query: 237  KFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEP 296
            KFIRINFDV GYIVGANIETYLLEKSRAIRQA++ERTFHIFYY+++GA E +++DLLLE 
Sbjct: 251  KFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEG 310

Query: 297  YNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKK 356
            +N Y FLSNG V IP  QD +MFQET+EAM IMG  EEEQ+ +L+V+S VLQLGNIVFKK
Sbjct: 311  FNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKK 370

Query: 357  ERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEA 416
            ERNTDQASMPDNTAAQKV HL+GINVTDFTR ILTPRIKVGRD VQKAQTKEQADFA+EA
Sbjct: 371  ERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEA 430

Query: 417  LAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKL 476
            LAKATYER+FRW++ R+NKALDKT RQGASF+GILDIAGFEIF++NSFEQLCINYTNEKL
Sbjct: 431  LAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKL 490

Query: 477  QQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPK 536
            QQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI+LIE+P  PPG+LALLDEECWFPK
Sbjct: 491  QQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPK 550

Query: 537  ATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNI 596
            ATDKSFVEK+  EQG+HPKFQKPKQLKDK +F IIHYAGKVDY A  WL KNMDPLNDN+
Sbjct: 551  ATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNV 610

Query: 597  ATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAK 656
             +LL+ SSDKFV++LWKDVDRI+GLDQ+A M+E++LP A KT+KGMFRTVGQLYKEQL K
Sbjct: 611  TSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 670

Query: 657  LMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQE 716
            LM TLRNT PNFVRCIIPNHEK++GKLD  LVL+QLRCNGVLEGIRICRQGFPNR+VFQE
Sbjct: 671  LMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQE 730

Query: 717  FRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERD 776
            FRQRYEIL  N+IPKGFMDGKQAC+LMIKALELD NLYRIGQSK+FFR GVLAHLEEERD
Sbjct: 731  FRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERD 790

Query: 777  LKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKP 836
            LKITDVI+ FQA CRGYLARKAFAKRQQQLTAMKV+QRNCAAYLKLRNWQWWRLFTKVKP
Sbjct: 791  LKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKP 850

Query: 837  LLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELC 896
            LLQV+RQEEEM AKE+EL K +E+Q  AEN L E+E   SQL  EK  LQEQLQAETEL 
Sbjct: 851  LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910

Query: 897  AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
            AEAEE+R RL AKKQELEEI H++EAR+EEEE+R Q LQAE+KKM Q + +LEEQLEEEE
Sbjct: 911  AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970

Query: 957  SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSK 1016
            +ARQKLQLEKVT EAK+KKLE+E ++++DQN KL+KE+KLLE+RI++ TTNL EEEEK+K
Sbjct: 971  AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030

Query: 1017 SLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKM 1076
            +L KLKNKHE+MI++LE RL++EEK RQELEK +RKLEGD++D  +QIA+LQAQIAELKM
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090

Query: 1077 QLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRD 1136
            QLAKKEEELQAALAR+++E AQKN ALKKIRELE  IS+LQEDL+SERA+RNKAEKQKRD
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD 1150

Query: 1137 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQ 1196
            LGEELEALKTELEDTLDSTA QQELR+KREQEV +LKK L+EE ++HEAQ+QEMRQKH+Q
Sbjct: 1151 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1210

Query: 1197 AVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQE 1256
            AVEEL EQLEQ KR KANL+K KQTLE E  +LA E++VL Q K + EHK+KK+EAQ+QE
Sbjct: 1211 AVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 1270

Query: 1257 LQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQEL 1316
            LQ K ++GER R EL DKV KLQ E+++VTG+L++++ K+ KL KD ++L SQLQDTQEL
Sbjct: 1271 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1330

Query: 1317 LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDS 1376
            LQEE RQKL++STKL+Q+E+E+NS ++QL+EE EAK NLE+ I+TL+ Q++D KKK++D 
Sbjct: 1331 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1390

Query: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSA 1436
               +E  EE K++ QK++E L+Q++EEK AAYDKLEKTK RLQQELDDL+VDLD+QRQ  
Sbjct: 1391 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1450

Query: 1437 CNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELE 1496
             NLEKKQ+KFDQLLAEEK IS+KYA+ERDRAEAEAREKETKALSLARALEEA+E K ELE
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510

Query: 1497 RLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKL 1556
            R NK  + EMEDL+SSKDDVGK+VHELEKSKRALE Q+EEMKTQLEELEDELQATEDAKL
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1570

Query: 1557 RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLE 1616
            RLEVN+QA+K QFERDLQ RDEQ+EEK++QL RQ+ E E ELEDERKQR++A AA+KKLE
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630

Query: 1617 MDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLK 1676
             DLKDLE   DSA K R+EAIKQLRKLQAQMKD  REL+D RASR+EI A AKENEKK K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690

Query: 1677 SMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALEEKRRLEARIAQLE 1735
            S+EA+++QLQE+LAAAERA++QA  E++ELA+E+A+S SG+ AL  +EKRRLEARIAQLE
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ-DEKRRLEARIAQLE 1749

Query: 1736 EELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQ 1795
            EELEEEQGN E ++DR++KA  Q +Q++ +L  ERS AQKNE+ARQQLERQNKEL+ KL 
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1809

Query: 1796 EMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDER 1855
            EMEG VKSK+K++I ALEAKIAQLEEQ++ E +E+QAA K +++ +KKLK++LLQV+DER
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869

Query: 1856 RNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVS 1915
            + AEQYK+QA+K + R+KQLKRQLEEAEEE+QR NA+RRKLQREL++ATE+ +AM REV+
Sbjct: 1870 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1929

Query: 1916 SLKNKLRRGDLPFVVPRRMARKGA------GDGSDEEVDGK-ADGAEAKPAE 1960
            +LK+KLRRG+    VP R  R G        DGS+EE D + AD    K +E
Sbjct: 1930 ALKSKLRRGNETSFVPSR--RSGGRRVIENADGSEEETDTRDADFNGTKASE 1979


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 2940 bits (7621), Expect = 0.0
 Identities = 1479/1920 (77%), Positives = 1716/1920 (89%), Gaps = 5/1920 (0%)

Query: 7    DKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVK 66
            +K+L+VDKNFIN+P+AQADWAAK+LVWVPS+K GFE AS+KEE G+E +VELVENGKKV 
Sbjct: 11   EKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVT 70

Query: 67   VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKN 126
            V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL+ERY+SGLIYTYSGLFCVV+NPYK+
Sbjct: 71   VGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKH 130

Query: 127  LPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKK 186
            LPIYSE+IV+MYKGKKRHEMPPHIYAI DTAYRSM+QDREDQSILCTGESGAGKTENTKK
Sbjct: 131  LPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKK 190

Query: 187  VIQYLAYVASSHKSKKDQ---GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 243
            VIQYLA VASSHK KKD    GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF
Sbjct: 191  VIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 250

Query: 244  DVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFL 303
            DV GYIVGANIETYLLEKSRAIRQA++ERTFHIFYY+++GA E +++DLLLE +N Y FL
Sbjct: 251  DVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFL 310

Query: 304  SNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQA 363
            SNG V IP  QD +MFQET+EAM IMG  EEEQ+ +L+V+S VLQLGNIVFKKERNTDQA
Sbjct: 311  SNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQA 370

Query: 364  SMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYE 423
            SMPDNTAAQKV HL+GINVTDFTR ILTPRIKVGRD VQKAQTKEQADFA+EALAKATYE
Sbjct: 371  SMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYE 430

Query: 424  RMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHT 483
            R+FRW++ R+NKALDKT RQGASF+GILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHT
Sbjct: 431  RLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHT 490

Query: 484  MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFV 543
            MFILEQEEYQREGIEWNFIDFGLDLQPCI+LIE+P  PPG+LALLDEECWFPKATDKSFV
Sbjct: 491  MFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFV 550

Query: 544  EKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQS 603
            EK+  EQG+HPKFQKPKQLKDK +F IIHYAGKVDY A  WL KNMDPLNDN+ +LL+ S
Sbjct: 551  EKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNAS 610

Query: 604  SDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRN 663
            SDKFV++LWKDVDRI+GLDQ+A M+E++LP A KT+KGMFRTVGQLYKEQL KLM TLRN
Sbjct: 611  SDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRN 670

Query: 664  TNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEI 723
            T PNFVRCIIPNHEK++GKLD  LVL+QLRCNGVLEGIRICRQGFPNR+VFQEFRQRYEI
Sbjct: 671  TTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 730

Query: 724  LTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVI 783
            L  N+IPKGFMDGKQAC+LMIKALELD NLYRIGQSK+FFR GVLAHLEEERDLKITDVI
Sbjct: 731  LAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVI 790

Query: 784  IGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQ 843
            + FQA CRGYLARKAFAKRQQQLTAMKV+QRNCAAYLKLRNWQWWRLFTKVKPLLQV+RQ
Sbjct: 791  MAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQ 850

Query: 844  EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
            EEEM AKE+EL K +E+Q  AEN L E+E   SQL  EK  LQEQLQAETEL AEAEE+R
Sbjct: 851  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910

Query: 904  ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
             RL AKKQELEEI H++EAR+EEEE+R Q LQAE+KKM Q + +LEEQLEEEE+ARQKLQ
Sbjct: 911  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970

Query: 964  LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKN 1023
            LEKVT EAK+KKLE+E ++++DQN KL+KE+KLLE+RI++ TTNL EEEEK+K+L KLKN
Sbjct: 971  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030

Query: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
            KHE+MI++LE RL++EEK RQELEK +RKLEGD++D  +QIA+LQAQIAELKMQLAKKEE
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090

Query: 1084 ELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEA 1143
            ELQAALAR+++E AQKN ALKKIRELE  IS+LQEDL+SERA+RNKAEKQKRDLGEELEA
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150

Query: 1144 LKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAE 1203
            LKTELEDTLDSTA QQELR+KREQEV +LKK L+EE ++HEAQ+QEMRQKH+QAVEEL E
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210

Query: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263
            QLEQ KR KANL+K KQTLE E  +LA E++VL Q K + EHK+KK+EAQ+QELQ K ++
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270

Query: 1264 GERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ 1323
            GER R EL DKV KLQ E+++VTG+L++++ K+ KL KD ++L SQLQDTQELLQEE RQ
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330

Query: 1324 KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETA 1383
            KL++STKL+Q+E+E+NS ++QL+EE EAK NLE+ I+TL+ Q++D KKK++D    +E  
Sbjct: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL 1390

Query: 1384 EEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ 1443
            EE K++ QK++E L+Q++EEK AAYDKLEKTK RLQQELDDL+VDLD+QRQ   NLEKKQ
Sbjct: 1391 EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450

Query: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFR 1503
            +KFDQLLAEEK IS+KYA+ERDRAEAEAREKETKALSLARALEEA+E K ELER NK  +
Sbjct: 1451 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1510

Query: 1504 TEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQ 1563
             EMEDL+SSKDDVGK+VHELEKSKRALE Q+EEMKTQLEELEDELQATEDAKLRLEVN+Q
Sbjct: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570

Query: 1564 AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
            A+K QFERDLQ RDEQ+EEK++QL RQ+ E E ELEDERKQR++A AA+KKLE DLKDLE
Sbjct: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630

Query: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
               DSA K R+EAIKQLRKLQAQMKD  REL+D RASR+EI A AKENEKK KS+EA+++
Sbjct: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1690

Query: 1684 QLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALEEKRRLEARIAQLEEELEEEQ 1742
            QLQE+LAAAERA++QA  E++ELA+E+A+S SG+ AL  +EKRRLEARIAQLEEELEEEQ
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ-DEKRRLEARIAQLEEELEEEQ 1749

Query: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
            GN E ++DR++KA  Q +Q++ +L  ERS AQKNE+ARQQLERQNKEL+ KL EMEG VK
Sbjct: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 1809

Query: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862
            SK+K++I ALEAKIAQLEEQ++ E +E+QAA K +++ +KKLK++LLQV+DER+ AEQYK
Sbjct: 1810 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYK 1869

Query: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            +QA+K + R+KQLKRQLEEAEEE+QR NA+RRKLQREL++ATE+ +AM REV++LK+KLR
Sbjct: 1870 EQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score =  254 bits (649), Expect = 6e-67
 Identities = 233/968 (24%), Positives = 444/968 (45%), Gaps = 79/968 (8%)

Query: 1014 KSKSLAKLKNKHEAM------ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI--- 1064
            K K L ++  + E M      +   +ER ++ E + +ELE+   +L  +   L +Q+   
Sbjct: 840  KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899

Query: 1065 AELQAQIAELKMQLAKKEEELQAAL----ARVEEEAAQKNMALKKIRELESQISELQEDL 1120
             EL A+  E++++LA K++EL+  L    AR+EEE  +      + +++  Q+ +L+E L
Sbjct: 900  TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959

Query: 1121 ESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA 1180
            E E A+R K + +K     +++ L+ E+    D      + R   E+ ++ L   L EE 
Sbjct: 960  EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019

Query: 1181 KTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGK 1240
            +  +  + +++ KH   + EL  +L++ ++ +  LEK K+ LE +  +   ++  L    
Sbjct: 1020 EKAK-NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078

Query: 1241 GDSEHKRKKVEAQLQ--------ELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQS 1292
             + + +  K E +LQ        E+  K N  +++R EL   ++ LQ +LD+     +++
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKA 1137

Query: 1293 DSKSSKLTKDFSALESQLQDTQE--LLQEENRQKLSLS-TKLKQVEDEKN---------- 1339
            + +   L ++  AL+++L+DT +    Q+E R K     T LK+  DE+           
Sbjct: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1197

Query: 1340 ---------SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL 1390
                        EQLE+ + AK NL+K   TL  + AD+  ++       +  E  K+KL
Sbjct: 1198 RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKL 1257

Query: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLL 1450
            +  ++ L  +  +   A  +L     +LQ E++ +   L+     A  L K        L
Sbjct: 1258 EAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1317

Query: 1451 AEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLM 1510
             + + +  +   ++     + R+ E +  SL   L+E ME K  LER       ++ D  
Sbjct: 1318 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1377

Query: 1511 SSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570
                D   +V  LE+ K+  ++++E +  Q EE        E  K RL+  L  +    +
Sbjct: 1378 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437

Query: 1571 --RDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
              R L    E+ + K  QL+ + + + ++  DER +   A A  ++ E     L   ++ 
Sbjct: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR---AEAEAREKETKALSLARALEE 1494

Query: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
            A + ++E  +  + L+A+M+D +   DD   +  E+    +  E +++ M+ ++ +L++E
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1554

Query: 1689 LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR-LEARIAQLEEELEEEQGNTEL 1747
            L A E AK + +     L  +            EEKRR L+ ++ + E ELE+E+    L
Sbjct: 1555 LQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1614

Query: 1748 INDRLKKANLQIDQINTDLNLERSHAQKN-ENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
                 KK    +     DL L+   A K  E A +QL +   ++K   +E+E    S+ +
Sbjct: 1615 AAAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDE 1670

Query: 1807 ASITA---------LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRN 1857
               TA         LEA + QL+E L    + R+ A  +     ++L   L       RN
Sbjct: 1671 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL-----SGRN 1725

Query: 1858 AEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSL 1917
            A Q  D+  +   R+ QL+ +LEE +   +  +   RK       AT+ A+ ++ E+++ 
Sbjct: 1726 ALQ--DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK-------ATQQAEQLSNELATE 1776

Query: 1918 KNKLRRGD 1925
            ++  ++ +
Sbjct: 1777 RSTAQKNE 1784



 Score =  162 bits (410), Expect = 3e-39
 Identities = 153/657 (23%), Positives = 304/657 (46%), Gaps = 82/657 (12%)

Query: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELD- 1423
            QV   +++M+     L+  +E ++K + +L+ L Q+H +       L + K  LQ++L  
Sbjct: 846  QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQ-------LTEEKNLLQEQLQA 898

Query: 1424 --DLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE---AEAREKETKA 1478
              +L  + +  R     L  K+++ +++L E   + A+  EE DR +   AE ++   + 
Sbjct: 899  ETELYAEAEEMR---VRLAAKKQELEEILHE---MEARLEEEEDRGQQLQAERKKMAQQM 952

Query: 1479 LSLARALEE--AMEQKAELERLNKQFRTE-MEDLMSSKDDVGKSVHELEKSKRALEQQVE 1535
            L L   LEE  A  QK +LE++  + + + +ED +   DD     ++L K ++ LE+++ 
Sbjct: 953  LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN---NKLSKERKLLEERIS 1009

Query: 1536 EMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDE----------------- 1578
            ++ T L E E++ +     K + E  +  ++ + +++ + R E                 
Sbjct: 1010 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069

Query: 1579 -------QSEEKKKQLVRQVREMEA---ELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
                   Q  E K QL ++  E++A    L+DE  Q++ A+   ++LE  + DL+  +DS
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129

Query: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDT----------RASRE-EILAQAKENEKKLKS 1677
                R++A KQ R L  +++    EL+DT          RA RE E+    K  +++ +S
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1189

Query: 1678 MEAEMIQLQEELAAA-----------ERAKRQAQQERDELADEIANSSGK----GALALE 1722
             EA++ +++++ A A           +RAK    + +  L  E A+ +G+    G    E
Sbjct: 1190 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1249

Query: 1723 ---EKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENA 1779
               +K++LEA++ +L+ +  + +     +ND++ K   +++ +   LN     A K    
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309

Query: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRR 1839
               L  Q ++ +  LQE E   K      +  LE +   L++QLD E + +Q   + +  
Sbjct: 1310 VASLSSQLQDTQELLQE-ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1368

Query: 1840 TEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE 1899
               +L D   ++ D     E  ++   +    ++ L +Q EE      +   ++ +LQ+E
Sbjct: 1369 LNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1428

Query: 1900 LEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEA 1956
            L+D     D   + VS+L+ K R+ D      + ++ K A +    E + +    +A
Sbjct: 1429 LDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485



 Score =  135 bits (341), Expect = 3e-31
 Identities = 119/511 (23%), Positives = 242/511 (47%), Gaps = 20/511 (3%)

Query: 834  VKPLLQVSRQEEEMMAKEEELV-KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAE 892
            V  L +  R+ ++++A+E+ +  K  +++  AE    E ET    L      L+E L+A+
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARA---LEEALEAK 1499

Query: 893  TELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQL 952
             EL    E     L A+ ++L     D+   V E E+  + L+ + ++M+  ++ELE++L
Sbjct: 1500 EEL----ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555

Query: 953  EEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE 1012
            +  E A+ +L+   V  +A   + E +    ++QN    ++++ L+ ++ E+ T L +E 
Sbjct: 1556 QATEDAKLRLE---VNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETELEDER 1609

Query: 1013 EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA--- 1069
            ++    A  K K E  + DLE +     K R+E  K  RKL+    D   ++ + +A   
Sbjct: 1610 KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD 1669

Query: 1070 QIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNK 1129
            +I     +  KK + L+A L +++E+ A    A +K  +LE +  EL E+L S  + RN 
Sbjct: 1670 EIFATAKENEKKAKSLEADLMQLQEDLAAAERA-RKQADLEKE--ELAEELASSLSGRNA 1726

Query: 1130 AEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQE 1189
             + +KR L   +  L+ ELE+   +  A  +   K  Q+   L   L  E  T +     
Sbjct: 1727 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1786

Query: 1190 MRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKK 1249
             +Q   Q  E  ++  E    VK+  +     LE +  +L  +V+   + K  +    K+
Sbjct: 1787 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846

Query: 1250 VEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQ 1309
             + +L+E+ ++  +  ++  +  ++  K    +  +   L +++ +S ++  +   L+ +
Sbjct: 1847 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906

Query: 1310 LQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
            L +  E  +   R+  +L +KL+    ++ S
Sbjct: 1907 LDEATESNEAMGREVNALKSKLRGPPPQETS 1937


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 2937 bits (7614), Expect = 0.0
 Identities = 1479/1927 (76%), Positives = 1716/1927 (89%), Gaps = 12/1927 (0%)

Query: 7    DKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVK 66
            +K+L+VDKNFIN+P+AQADWAAK+LVWVPS+K GFE AS+KEE G+E +VELVENGKKV 
Sbjct: 11   EKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVT 70

Query: 67   VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKN 126
            V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL+ERY+SGLIYTYSGLFCVV+NPYK+
Sbjct: 71   VGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKH 130

Query: 127  LPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKK 186
            LPIYSE+IV+MYKGKKRHEMPPHIYAI DTAYRSM+QDREDQSILCTGESGAGKTENTKK
Sbjct: 131  LPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKK 190

Query: 187  VIQYLAYVASSHKSKKDQ----------GELERQLLQANPILEAFGNAKTVKNDNSSRFG 236
            VIQYLA VASSHK KKD           GELE+QLLQANPILEAFGNAKTVKNDNSSRFG
Sbjct: 191  VIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFG 250

Query: 237  KFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEP 296
            KFIRINFDV GYIVGANIETYLLEKSRAIRQA++ERTFHIFYY+++GA E +++DLLLE 
Sbjct: 251  KFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEG 310

Query: 297  YNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKK 356
            +N Y FLSNG V IP  QD +MFQET+EAM IMG  EEEQ+ +L+V+S VLQLGNIVFKK
Sbjct: 311  FNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKK 370

Query: 357  ERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEA 416
            ERNTDQASMPDNTAAQKV HL+GINVTDFTR ILTPRIKVGRD VQKAQTKEQADFA+EA
Sbjct: 371  ERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEA 430

Query: 417  LAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKL 476
            LAKATYER+FRW++ R+NKALDKT RQGASF+GILDIAGFEIF++NSFEQLCINYTNEKL
Sbjct: 431  LAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKL 490

Query: 477  QQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPK 536
            QQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI+LIE+P  PPG+LALLDEECWFPK
Sbjct: 491  QQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPK 550

Query: 537  ATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNI 596
            ATDKSFVEK+  EQG+HPKFQKPKQLKDK +F IIHYAGKVDY A  WL KNMDPLNDN+
Sbjct: 551  ATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNV 610

Query: 597  ATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAK 656
             +LL+ SSDKFV++LWKDVDRI+GLDQ+A M+E++LP A KT+KGMFRTVGQLYKEQL K
Sbjct: 611  TSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 670

Query: 657  LMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQE 716
            LM TLRNT PNFVRCIIPNHEK++GKLD  LVL+QLRCNGVLEGIRICRQGFPNR+VFQE
Sbjct: 671  LMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQE 730

Query: 717  FRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERD 776
            FRQRYEIL  N+IPKGFMDGKQAC+LMIKALELD NLYRIGQSK+FFR GVLAHLEEERD
Sbjct: 731  FRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERD 790

Query: 777  LKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKP 836
            LKITDVI+ FQA CRGYLARKAFAKRQQQLTAMKV+QRNCAAYLKLRNWQWWRLFTKVKP
Sbjct: 791  LKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKP 850

Query: 837  LLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELC 896
            LLQV+RQEEEM AKE+EL K +E+Q  AEN L E+E   SQL  EK  LQEQLQAETEL 
Sbjct: 851  LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910

Query: 897  AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
            AEAEE+R RL AKKQELEEI H++EAR+EEEE+R Q LQAE+KKM Q + +LEEQLEEEE
Sbjct: 911  AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970

Query: 957  SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSK 1016
            +ARQKLQLEKVT EAK+KKLE+E ++++DQN KL+KE+KLLE+RI++ TTNL EEEEK+K
Sbjct: 971  AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030

Query: 1017 SLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKM 1076
            +L KLKNKHE+MI++LE RL++EEK RQELEK +RKLEGD++D  +QIA+LQAQIAELKM
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090

Query: 1077 QLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRD 1136
            QLAKKEEELQAALAR+++E AQKN ALKKIRELE  IS+LQEDL+SERA+RNKAEKQKRD
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD 1150

Query: 1137 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQ 1196
            LGEELEALKTELEDTLDSTA QQELR+KREQEV +LKK L+EE ++HEAQ+QEMRQKH+Q
Sbjct: 1151 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1210

Query: 1197 AVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQE 1256
            AVEEL EQLEQ KR KANL+K KQTLE E  +LA E++VL Q K + EHK+KK+EAQ+QE
Sbjct: 1211 AVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 1270

Query: 1257 LQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQEL 1316
            LQ K ++GER R EL DKV KLQ E+++VTG+L++++ K+ KL KD ++L SQLQDTQEL
Sbjct: 1271 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1330

Query: 1317 LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDS 1376
            LQEE RQKL++STKL+Q+E+E+NS ++QL+EE EAK NLE+ I+TL+ Q++D KKK++D 
Sbjct: 1331 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1390

Query: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSA 1436
               +E  EE K++ QK++E L+Q++EEK AAYDKLEKTK RLQQELDDL+VDLD+QRQ  
Sbjct: 1391 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1450

Query: 1437 CNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELE 1496
             NLEKKQ+KFDQLLAEEK IS+KYA+ERDRAEAEAREKETKALSLARALEEA+E K ELE
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510

Query: 1497 RLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKL 1556
            R NK  + EMEDL+SSKDDVGK+VHELEKSKRALE Q+EEMKTQLEELEDELQATEDAKL
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1570

Query: 1557 RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLE 1616
            RLEVN+QA+K QFERDLQ RDEQ+EEK++QL RQ+ E E ELEDERKQR++A AA+KKLE
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630

Query: 1617 MDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLK 1676
             DLKDLE   DSA K R+EAIKQLRKLQAQMKD  REL+D RASR+EI A AKENEKK K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690

Query: 1677 SMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALEEKRRLEARIAQLE 1735
            S+EA+++QLQE+LAAAERA++QA  E++ELA+E+A+S SG+ AL  +EKRRLEARIAQLE
Sbjct: 1691 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ-DEKRRLEARIAQLE 1749

Query: 1736 EELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQ 1795
            EELEEEQGN E ++DR++KA  Q +Q++ +L  ERS AQKNE+ARQQLERQNKEL+ KL 
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH 1809

Query: 1796 EMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDER 1855
            EMEG VKSK+K++I ALEAKIAQLEEQ++ E +E+QAA K +++ +KKLK++LLQV+DER
Sbjct: 1810 EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER 1869

Query: 1856 RNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVS 1915
            + AEQYK+QA+K + R+KQLKRQLEEAEEE+QR NA+RRKLQREL++ATE+ +AM REV+
Sbjct: 1870 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVN 1929

Query: 1916 SLKNKLR 1922
            +LK+KLR
Sbjct: 1930 ALKSKLR 1936



 Score =  254 bits (649), Expect = 6e-67
 Identities = 233/968 (24%), Positives = 444/968 (45%), Gaps = 79/968 (8%)

Query: 1014 KSKSLAKLKNKHEAM------ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI--- 1064
            K K L ++  + E M      +   +ER ++ E + +ELE+   +L  +   L +Q+   
Sbjct: 847  KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906

Query: 1065 AELQAQIAELKMQLAKKEEELQAAL----ARVEEEAAQKNMALKKIRELESQISELQEDL 1120
             EL A+  E++++LA K++EL+  L    AR+EEE  +      + +++  Q+ +L+E L
Sbjct: 907  TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 966

Query: 1121 ESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA 1180
            E E A+R K + +K     +++ L+ E+    D      + R   E+ ++ L   L EE 
Sbjct: 967  EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1026

Query: 1181 KTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGK 1240
            +  +  + +++ KH   + EL  +L++ ++ +  LEK K+ LE +  +   ++  L    
Sbjct: 1027 EKAK-NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085

Query: 1241 GDSEHKRKKVEAQLQ--------ELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQS 1292
             + + +  K E +LQ        E+  K N  +++R EL   ++ LQ +LD+     +++
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKA 1144

Query: 1293 DSKSSKLTKDFSALESQLQDTQE--LLQEENRQKLSLS-TKLKQVEDEKN---------- 1339
            + +   L ++  AL+++L+DT +    Q+E R K     T LK+  DE+           
Sbjct: 1145 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1204

Query: 1340 ---------SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL 1390
                        EQLE+ + AK NL+K   TL  + AD+  ++       +  E  K+KL
Sbjct: 1205 RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKL 1264

Query: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLL 1450
            +  ++ L  +  +   A  +L     +LQ E++ +   L+     A  L K        L
Sbjct: 1265 EAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1324

Query: 1451 AEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLM 1510
             + + +  +   ++     + R+ E +  SL   L+E ME K  LER       ++ D  
Sbjct: 1325 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1384

Query: 1511 SSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570
                D   +V  LE+ K+  ++++E +  Q EE        E  K RL+  L  +    +
Sbjct: 1385 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1444

Query: 1571 --RDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
              R L    E+ + K  QL+ + + + ++  DER +   A A  ++ E     L   ++ 
Sbjct: 1445 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR---AEAEAREKETKALSLARALEE 1501

Query: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
            A + ++E  +  + L+A+M+D +   DD   +  E+    +  E +++ M+ ++ +L++E
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1561

Query: 1689 LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR-LEARIAQLEEELEEEQGNTEL 1747
            L A E AK + +     L  +            EEKRR L+ ++ + E ELE+E+    L
Sbjct: 1562 LQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1621

Query: 1748 INDRLKKANLQIDQINTDLNLERSHAQKN-ENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
                 KK    +     DL L+   A K  E A +QL +   ++K   +E+E    S+ +
Sbjct: 1622 AAAAKKKLEGDLK----DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDE 1677

Query: 1807 ASITA---------LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRN 1857
               TA         LEA + QL+E L    + R+ A  +     ++L   L       RN
Sbjct: 1678 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSL-----SGRN 1732

Query: 1858 AEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSL 1917
            A Q  D+  +   R+ QL+ +LEE +   +  +   RK       AT+ A+ ++ E+++ 
Sbjct: 1733 ALQ--DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK-------ATQQAEQLSNELATE 1783

Query: 1918 KNKLRRGD 1925
            ++  ++ +
Sbjct: 1784 RSTAQKNE 1791



 Score =  162 bits (410), Expect = 3e-39
 Identities = 153/657 (23%), Positives = 304/657 (46%), Gaps = 82/657 (12%)

Query: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELD- 1423
            QV   +++M+     L+  +E ++K + +L+ L Q+H +       L + K  LQ++L  
Sbjct: 853  QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQ-------LTEEKNLLQEQLQA 905

Query: 1424 --DLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE---AEAREKETKA 1478
              +L  + +  R     L  K+++ +++L E   + A+  EE DR +   AE ++   + 
Sbjct: 906  ETELYAEAEEMR---VRLAAKKQELEEILHE---MEARLEEEEDRGQQLQAERKKMAQQM 959

Query: 1479 LSLARALEE--AMEQKAELERLNKQFRTE-MEDLMSSKDDVGKSVHELEKSKRALEQQVE 1535
            L L   LEE  A  QK +LE++  + + + +ED +   DD     ++L K ++ LE+++ 
Sbjct: 960  LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN---NKLSKERKLLEERIS 1016

Query: 1536 EMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDE----------------- 1578
            ++ T L E E++ +     K + E  +  ++ + +++ + R E                 
Sbjct: 1017 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076

Query: 1579 -------QSEEKKKQLVRQVREMEA---ELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
                   Q  E K QL ++  E++A    L+DE  Q++ A+   ++LE  + DL+  +DS
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1136

Query: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDT----------RASRE-EILAQAKENEKKLKS 1677
                R++A KQ R L  +++    EL+DT          RA RE E+    K  +++ +S
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1196

Query: 1678 MEAEMIQLQEELAAA-----------ERAKRQAQQERDELADEIANSSGK----GALALE 1722
             EA++ +++++ A A           +RAK    + +  L  E A+ +G+    G    E
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1256

Query: 1723 ---EKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENA 1779
               +K++LEA++ +L+ +  + +     +ND++ K   +++ +   LN     A K    
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316

Query: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRR 1839
               L  Q ++ +  LQE E   K      +  LE +   L++QLD E + +Q   + +  
Sbjct: 1317 VASLSSQLQDTQELLQE-ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1375

Query: 1840 TEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE 1899
               +L D   ++ D     E  ++   +    ++ L +Q EE      +   ++ +LQ+E
Sbjct: 1376 LNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1435

Query: 1900 LEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEA 1956
            L+D     D   + VS+L+ K R+ D      + ++ K A +    E + +    +A
Sbjct: 1436 LDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492



 Score =  135 bits (341), Expect = 3e-31
 Identities = 119/511 (23%), Positives = 242/511 (47%), Gaps = 20/511 (3%)

Query: 834  VKPLLQVSRQEEEMMAKEEELV-KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAE 892
            V  L +  R+ ++++A+E+ +  K  +++  AE    E ET    L      L+E L+A+
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARA---LEEALEAK 1506

Query: 893  TELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQL 952
             EL    E     L A+ ++L     D+   V E E+  + L+ + ++M+  ++ELE++L
Sbjct: 1507 EEL----ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1562

Query: 953  EEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE 1012
            +  E A+ +L+   V  +A   + E +    ++QN    ++++ L+ ++ E+ T L +E 
Sbjct: 1563 QATEDAKLRLE---VNMQALKGQFERDLQARDEQN---EEKRRQLQRQLHEYETELEDER 1616

Query: 1013 EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA--- 1069
            ++    A  K K E  + DLE +     K R+E  K  RKL+    D   ++ + +A   
Sbjct: 1617 KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD 1676

Query: 1070 QIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNK 1129
            +I     +  KK + L+A L +++E+ A    A +K  +LE +  EL E+L S  + RN 
Sbjct: 1677 EIFATAKENEKKAKSLEADLMQLQEDLAAAERA-RKQADLEKE--ELAEELASSLSGRNA 1733

Query: 1130 AEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQE 1189
             + +KR L   +  L+ ELE+   +  A  +   K  Q+   L   L  E  T +     
Sbjct: 1734 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1793

Query: 1190 MRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKK 1249
             +Q   Q  E  ++  E    VK+  +     LE +  +L  +V+   + K  +    K+
Sbjct: 1794 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1853

Query: 1250 VEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQ 1309
             + +L+E+ ++  +  ++  +  ++  K    +  +   L +++ +S ++  +   L+ +
Sbjct: 1854 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913

Query: 1310 LQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
            L +  E  +   R+  +L +KL+    ++ S
Sbjct: 1914 LDEATESNEAMGREVNALKSKLRGPPPQETS 1944


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 2539 bits (6580), Expect = 0.0
 Identities = 1267/1941 (65%), Positives = 1589/1941 (81%), Gaps = 8/1941 (0%)

Query: 23   QADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSK 82
            Q +W A++LVWVPS+  GFE A+L++E  EEA VEL E+G+++++ +D IQ+MNPPKFSK
Sbjct: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106

Query: 83   VEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK 142
             EDMAELTCLNEASVLHNL+ERYYSGLIYTYSGLFCVVINPYK LPIY+E IVEMY+GKK
Sbjct: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166

Query: 143  RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKK 202
            RHE+PPH+YA+T+ AYRSM+QDREDQSILCTGESGAGKTENTKKVIQYLA+VASS K +K
Sbjct: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226

Query: 203  DQG---ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLL 259
            + G   ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVGANIETYLL
Sbjct: 227  EPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLL 286

Query: 260  EKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMF 319
            EKSRAIRQAK+E +FHIFY LL GAGE LK DLLLEP + YRFL+NG  + PGQ+ +++F
Sbjct: 287  EKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELF 345

Query: 320  QETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLG 379
            QET+E++R++G   EE + +LR++S VLQ GNI  K+ERNTDQA+MPDNTAAQK+  LLG
Sbjct: 346  QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405

Query: 380  INVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDK 439
            + VTDF+R +LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYER+FRWLVLR+N+ALD+
Sbjct: 406  LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDR 465

Query: 440  TKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 499
            + RQGASF+GILDIAGFEIF LNSFEQLCINYTNEKLQQLFNHTMF+LEQEEYQREGI W
Sbjct: 466  SPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPW 525

Query: 500  NFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKP 559
             F+DFGLDLQPCIDLIE+PA PPG+LALLDEECWFPKATDKSFVEKV QEQG HPKFQ+P
Sbjct: 526  TFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP 585

Query: 560  KQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRII 619
            + L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDN+A LLHQS+D+  +E+WKDV+ I+
Sbjct: 586  RHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645

Query: 620  GLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKK 679
            GL+QV+ + +   P   + R+GMFRTVGQLYKE L++LMATL NTNP+FVRCI+PNHEK+
Sbjct: 646  GLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703

Query: 680  AGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQA 739
            AGKL+P LVLDQLRCNGVLEGIRICRQGFPNR++FQEFRQRYEILTPN+IPKGFMDGKQA
Sbjct: 704  AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763

Query: 740  CVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAF 799
            C  MI+ALELD NLYR+GQSK+FFRAGVLA LEEERDLK+TD+I+ FQA  RGYLAR+AF
Sbjct: 764  CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823

Query: 800  AKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVRE 859
             KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQV+RQ+E + A+ +EL KV+E
Sbjct: 824  QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883

Query: 860  KQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHD 919
             Q  +   + E++   +QL  E+ +L EQL+AE ELCAEAEE R RL A+KQELE +  +
Sbjct: 884  LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943

Query: 920  LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979
            LEARV EEEE  + +Q EKK++QQ+IQELE  LE EE ARQKLQLEKVTTEAK+KK EE+
Sbjct: 944  LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003

Query: 980  QIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE 1039
             ++LEDQN KL+KE+KLLEDR+AEF++   EEEEK KSL KL+ K+EA I D+E+RLR+E
Sbjct: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063

Query: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099
            EK RQELEK +R+L+G+S++L +Q+ E Q +  EL+ QL +KEEELQAALAR E+E   +
Sbjct: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123

Query: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
               LK +RE ++ ++E QEDLESER +R KAEKQ+RDLGEELEAL+ ELEDTLDST AQQ
Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183

Query: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
            ELRSKREQEV  LKKTLEEE + HEA +QE+RQ+H QA+ ELAEQLEQ +R K   EK +
Sbjct: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243

Query: 1220 QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279
              LE E  EL  E+  L   + + E +R+++E QLQE+Q +  +GER R E A+K+ + Q
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303

Query: 1280 VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339
             EL+NV+G L++++SK+ +L+K+ S+ E+QL D QELLQEE R KL+L ++++ +E E  
Sbjct: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363

Query: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399
              REQLEEE  A+    +++ T  AQ+++ +++ E+  G LE  EE +R+  ++ E L+Q
Sbjct: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423

Query: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAK 1459
            R  EK    D+LE+ + RLQQELDD  +DL+ QRQ    LEKKQ+KFDQLLAEEK    +
Sbjct: 1424 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483

Query: 1460 YAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519
              EER+RAEAE RE+E +ALSL RALEE  E + ELER N+  R E+E L+SSKDDVGKS
Sbjct: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543

Query: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
            VHELE++ R  EQ   +++ Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQGRDE 
Sbjct: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603

Query: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639
             EE+++QL +Q+R+ E E ++ERKQR++AVAARKKLE +L++L+A + SA + ++EA+KQ
Sbjct: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663

Query: 1640 LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1699
            LRK+QAQMK+  RE+++TR SREEI +Q +E+EK+LK +EAE+++LQEELAA++RA+RQA
Sbjct: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723

Query: 1700 QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759
            QQ+RDE+ADE+AN +   A  LEEKR+LE R+ QLEEELEEEQ N+EL+NDR +K  LQ+
Sbjct: 1724 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1783

Query: 1760 DQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819
            + + T+L+ ERS + K E+ RQQLERQ +EL+ +L E +   ++++K +I ALE+K+AQ 
Sbjct: 1784 ESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQA 1843

Query: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQL 1879
            EEQL+ ET+ER  + K VRR EK+LK+V+LQV++ERR A+Q +DQ +K + R+KQLKRQL
Sbjct: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903

Query: 1880 EEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFV--VPRRMARK 1937
            EEAEEEA RA A RR+LQRELED TE+A++MNREV++L+N+LRRG L F     R++ R 
Sbjct: 1904 EEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRL 1963

Query: 1938 GAGDGSDEEVDGKADGAEAKP 1958
              G  SDEE +    G+   P
Sbjct: 1964 EEGVASDEEAEEAQPGSGPSP 1984


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 2536 bits (6572), Expect = 0.0
 Identities = 1267/1949 (65%), Positives = 1589/1949 (81%), Gaps = 16/1949 (0%)

Query: 23   QADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSK 82
            Q +W A++LVWVPS+  GFE A+L++E  EEA VEL E+G+++++ +D IQ+MNPPKFSK
Sbjct: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106

Query: 83   VEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK 142
             EDMAELTCLNEASVLHNL+ERYYSGLIYTYSGLFCVVINPYK LPIY+E IVEMY+GKK
Sbjct: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166

Query: 143  RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKK 202
            RHE+PPH+YA+T+ AYRSM+QDREDQSILCTGESGAGKTENTKKVIQYLA+VASS K +K
Sbjct: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226

Query: 203  DQG-----------ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVG 251
            + G           ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286

Query: 252  ANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIP 311
            ANIETYLLEKSRAIRQAK+E +FHIFY LL GAGE LK DLLLEP + YRFL+NG  + P
Sbjct: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346

Query: 312  GQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAA 371
            GQ+ +++FQET+E++R++G   EE + +LR++S VLQ GNI  K+ERNTDQA+MPDNTAA
Sbjct: 347  GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405

Query: 372  QKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVL 431
            QK+  LLG+ VTDF+R +LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYER+FRWLVL
Sbjct: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465

Query: 432  RINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEE 491
            R+N+ALD++ RQGASF+GILDIAGFEIF LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525

Query: 492  YQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQG 551
            YQREGI W F+DFGLDLQPCIDLIE+PA PPG+LALLDEECWFPKATDKSFVEKV QEQG
Sbjct: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585

Query: 552  THPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSEL 611
             HPKFQ+P+ L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDN+A LLHQS+D+  +E+
Sbjct: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645

Query: 612  WKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRC 671
            WKDV+ I+GL+QV+ + +   P   + R+GMFRTVGQLYKE L++LMATL NTNP+FVRC
Sbjct: 646  WKDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703

Query: 672  IIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPK 731
            I+PNHEK+AGKL+P LVLDQLRCNGVLEGIRICRQGFPNR++FQEFRQRYEILTPN+IPK
Sbjct: 704  IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763

Query: 732  GFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCR 791
            GFMDGKQAC  MI+ALELD NLYR+GQSK+FFRAGVLA LEEERDLK+TD+I+ FQA  R
Sbjct: 764  GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823

Query: 792  GYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKE 851
            GYLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQV+RQ+E + A+ 
Sbjct: 824  GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883

Query: 852  EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQ 911
            +EL KV+E Q  +   + E++   +QL  E+ +L EQL+AE ELCAEAEE R RL A+KQ
Sbjct: 884  QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943

Query: 912  ELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEA 971
            ELE +  +LEARV EEEE  + +Q EKK++QQ+IQELE  LE EE ARQKLQLEKVTTEA
Sbjct: 944  ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003

Query: 972  KLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD 1031
            K+KK EE+ ++LEDQN KL+KE+KLLEDR+AEF++   EEEEK KSL KL+ K+EA I D
Sbjct: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063

Query: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
            +E+RLR+EEK RQELEK +R+L+G+S++L +Q+ E Q +  EL+ QL +KEEELQAALAR
Sbjct: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123

Query: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
             E+E   +   LK +RE ++ ++E QEDLESER +R KAEKQ+RDLGEELEAL+ ELEDT
Sbjct: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183

Query: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211
            LDST AQQELRSKREQEV  LKKTLEEE + HEA +QE+RQ+H QA+ ELAEQLEQ +R 
Sbjct: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243

Query: 1212 KANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTEL 1271
            K   EK +  LE E  EL  E+  L   + + E +R+++E QLQE+Q +  +GER R E 
Sbjct: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303

Query: 1272 ADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL 1331
            A+K+ + Q EL+NV+G L++++SK+ +L+K+ S+ E+QL D QELLQEE R KL+L +++
Sbjct: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363

Query: 1332 KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQ 1391
            + +E E    REQLEEE  A+    +++ T  AQ+++ +++ E+  G LE  EE +R+  
Sbjct: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423

Query: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA 1451
            ++ E L+QR  EK    D+LE+ + RLQQELDD  +DL+ QRQ    LEKKQ+KFDQLLA
Sbjct: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483

Query: 1452 EEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS 1511
            EEK    +  EER+RAEAE RE+E +ALSL RALEE  E + ELER N+  R E+E L+S
Sbjct: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543

Query: 1512 SKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFER 1571
            SKDDVGKSVHELE++ R  EQ   +++ Q+ ELEDEL A EDAKLRLEV +QA+K Q ER
Sbjct: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603

Query: 1572 DLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANK 1631
            DLQGRDE  EE+++QL +Q+R+ E E ++ERKQR++AVAARKKLE +L++L+A + SA +
Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663

Query: 1632 NRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 1691
             ++EA+KQLRK+QAQMK+  RE+++TR SREEI +Q +E+EK+LK +EAE+++LQEELAA
Sbjct: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723

Query: 1692 AERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDR 1751
            ++RA+RQAQQ+RDE+ADE+AN +   A  LEEKR+LE R+ QLEEELEEEQ N+EL+NDR
Sbjct: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783

Query: 1752 LKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITA 1811
             +K  LQ++ + T+L+ ERS + K E+ RQQLERQ +EL+ +L E +   ++++K +I A
Sbjct: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843

Query: 1812 LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTR 1871
            LE+K+AQ EEQL+ ET+ER  + K VRR EK+LK+V+LQV++ERR A+Q +DQ +K + R
Sbjct: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903

Query: 1872 LKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFV-- 1929
            +KQLKRQLEEAEEEA RA A RR+LQRELED TE+A++MNREV++L+N+LRRG L F   
Sbjct: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTR 1963

Query: 1930 VPRRMARKGAGDGSDEEVDGKADGAEAKP 1958
              R++ R   G  SDEE +    G+   P
Sbjct: 1964 TVRQVFRLEEGVASDEEAEEAQPGSGPSP 1992


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 2519 bits (6528), Expect = 0.0
 Identities = 1267/1982 (63%), Positives = 1589/1982 (80%), Gaps = 49/1982 (2%)

Query: 23   QADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSK 82
            Q +W A++LVWVPS+  GFE A+L++E  EEA VEL E+G+++++ +D IQ+MNPPKFSK
Sbjct: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106

Query: 83   VEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK 142
             EDMAELTCLNEASVLHNL+ERYYSGLIYTYSGLFCVVINPYK LPIY+E IVEMY+GKK
Sbjct: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166

Query: 143  RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKK 202
            RHE+PPH+YA+T+ AYRSM+QDREDQSILCTGESGAGKTENTKKVIQYLA+VASS K +K
Sbjct: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226

Query: 203  DQG-----------ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVG 251
            + G           ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286

Query: 252  ANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIP 311
            ANIETYLLEKSRAIRQAK+E +FHIFY LL GAGE LK DLLLEP + YRFL+NG  + P
Sbjct: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346

Query: 312  GQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAA 371
            GQ+ +++FQET+E++R++G   EE + +LR++S VLQ GNI  K+ERNTDQA+MPDNTAA
Sbjct: 347  GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405

Query: 372  QKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVL 431
            QK+  LLG+ VTDF+R +LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYER+FRWLVL
Sbjct: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465

Query: 432  RINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEE 491
            R+N+ALD++ RQGASF+GILDIAGFEIF LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525

Query: 492  YQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQG 551
            YQREGI W F+DFGLDLQPCIDLIE+PA PPG+LALLDEECWFPKATDKSFVEKV QEQG
Sbjct: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585

Query: 552  THPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSEL 611
             HPKFQ+P+ L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDN+A LLHQS+D+  +E+
Sbjct: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645

Query: 612  WKD---------------------------------VDRIIGLDQVAGMSETALPGAFKT 638
            WKD                                 V+ I+GL+QV+ + +   P   + 
Sbjct: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703

Query: 639  RKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVL 698
            R+GMFRTVGQLYKE L++LMATL NTNP+FVRCI+PNHEK+AGKL+P LVLDQLRCNGVL
Sbjct: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763

Query: 699  EGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQ 758
            EGIRICRQGFPNR++FQEFRQRYEILTPN+IPKGFMDGKQAC  MI+ALELD NLYR+GQ
Sbjct: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823

Query: 759  SKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAA 818
            SK+FFRAGVLA LEEERDLK+TD+I+ FQA  RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 824  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883

Query: 819  YLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQL 878
            YLKLR+WQWWRLFTKVKPLLQV+RQ+E + A+ +EL KV+E Q  +   + E++   +QL
Sbjct: 884  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943

Query: 879  MAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK 938
              E+ +L EQL+AE ELCAEAEE R RL A+KQELE +  +LEARV EEEE  + +Q EK
Sbjct: 944  EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003

Query: 939  KKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
            K++QQ+IQELE  LE EE ARQKLQLEKVTTEAK+KK EE+ ++LEDQN KL+KE+KLLE
Sbjct: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063

Query: 999  DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
            DR+AEF++   EEEEK KSL KL+ K+EA I D+E+RLR+EEK RQELEK +R+L+G+S+
Sbjct: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123

Query: 1059 DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQE 1118
            +L +Q+ E Q +  EL+ QL +KEEELQAALAR E+E   +   LK +RE ++ ++E QE
Sbjct: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183

Query: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
            DLESER +R KAEKQ+RDLGEELEAL+ ELEDTLDST AQQELRSKREQEV  LKKTLEE
Sbjct: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243

Query: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
            E + HEA +QE+RQ+H QA+ ELAEQLEQ +R K   EK +  LE E  EL  E+  L  
Sbjct: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303

Query: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298
             + + E +R+++E QLQE+Q +  +GER R E A+K+ + Q EL+NV+G L++++SK+ +
Sbjct: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363

Query: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
            L+K+ S+ E+QL D QELLQEE R KL+L ++++ +E E    REQLEEE  A+    ++
Sbjct: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423

Query: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418
            + T  AQ+++ +++ E+  G LE  EE +R+  ++ E L+QR  EK    D+LE+ + RL
Sbjct: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483

Query: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478
            QQELDD  +DL+ QRQ    LEKKQ+KFDQLLAEEK    +  EER+RAEAE RE+E +A
Sbjct: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543

Query: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538
            LSL RALEE  E + ELER N+  R E+E L+SSKDDVGKSVHELE++ R  EQ   +++
Sbjct: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603

Query: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
             Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQGRDE  EE+++QL +Q+R+ E E 
Sbjct: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663

Query: 1599 EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTR 1658
            ++ERKQR++AVAARKKLE +L++L+A + SA + ++EA+KQLRK+QAQMK+  RE+++TR
Sbjct: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723

Query: 1659 ASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGA 1718
             SREEI +Q +E+EK+LK +EAE+++LQEELAA++RA+RQAQQ+RDE+ADE+AN +   A
Sbjct: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783

Query: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778
              LEEKR+LE R+ QLEEELEEEQ N+EL+NDR +K  LQ++ + T+L+ ERS + K E+
Sbjct: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843

Query: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1838
             RQQLERQ +EL+ +L E +   ++++K +I ALE+K+AQ EEQL+ ET+ER  + K VR
Sbjct: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903

Query: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQR 1898
            R EK+LK+V+LQV++ERR A+Q +DQ +K + R+KQLKRQLEEAEEEA RA A RR+LQR
Sbjct: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963

Query: 1899 ELEDATETADAMNREVSSLKNKLRRGDLPFV--VPRRMARKGAGDGSDEEVDGKADGAEA 1956
            ELED TE+A++MNREV++L+N+LRRG L F     R++ R   G  SDEE +    G+  
Sbjct: 1964 ELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGP 2023

Query: 1957 KP 1958
             P
Sbjct: 2024 SP 2025


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 1428 bits (3696), Expect = 0.0
 Identities = 786/1907 (41%), Positives = 1173/1907 (61%), Gaps = 28/1907 (1%)

Query: 29   KKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAE 88
            KK V+VP DK  F  A +    G +   E  E GK V V +D + + NPPKF K+EDMA 
Sbjct: 34   KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92

Query: 89   LTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPP 148
            LT L+E +VL+NLK+RY S +IYTYSGLFCV +NPYK LP+Y+ E+V  Y+GKKR E PP
Sbjct: 93   LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152

Query: 149  HIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS-SHKSKKDQ--- 204
            HI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A+   +SKKDQ   
Sbjct: 153  HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212

Query: 205  -GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSR 263
             G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLEKSR
Sbjct: 213  KGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 272

Query: 264  AIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDMFQE 321
             I Q K ER +HIFY +LS     L   LL+   PY+ Y F+S G  T+    D +    
Sbjct: 273  VIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYD-YAFISQGETTVASIDDAEELMA 331

Query: 322  TMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGIN 381
            T  A  ++G   EE+  + ++   ++  GN+ FK ++  +QA       A K ++L+G+N
Sbjct: 332  TDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLN 391

Query: 382  VTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTK 441
              D  +G+  PR+KVG +YV K Q  +Q  +A  ALAKA YERMF W+V RIN  L+ TK
Sbjct: 392  SADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE-TK 450

Query: 442  RQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 501
            +    FIG+LDIAGFEIFD NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW F
Sbjct: 451  QPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 510

Query: 502  IDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTHPKFQKPK 560
            IDFG+DLQ CIDLIEKP G   I+++L+EEC FPKATD +F  K+     G    FQKP+
Sbjct: 511  IDFGMDLQACIDLIEKPMG---IMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPR 567

Query: 561  QLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRI 618
             +K K  A F +IHYAG VDY    WL KN DPLN+ +  L  +SS K +S L+ +    
Sbjct: 568  NIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY--- 624

Query: 619  IGLDQVAGMSETALPGAFKTRKGM-FRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHE 677
                  AG       G  K +KG  F+TV  L++E L KLM  LR+T+P+FVRCIIPN  
Sbjct: 625  ------AGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNET 678

Query: 678  KKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDG 736
            K  G +D  LV+ QLRCNGVLEGIRICR+GFPNR+++ +FRQRY IL P +IP+G F+D 
Sbjct: 679  KSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDS 738

Query: 737  KQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLAR 796
            ++    ++ +L++D N Y+ G +KVFF+AG+L  LEE RD +++ +I   QA  RG LAR
Sbjct: 739  RKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLAR 798

Query: 797  KAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVK 856
              + K  ++  ++ V+Q N  A++ ++NW W +L+ K+KPLL+ + +E+EM + +EE  +
Sbjct: 799  MEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTR 858

Query: 857  VREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEI 916
            ++E    +E R  E+E     L+ EK  LQ Q+QAE +  A+AEE   +L   K +LE  
Sbjct: 859  LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAK 918

Query: 917  CHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKL 976
              ++  R+E+EEE    L A+K+K++    EL+  +++ E    K++ EK  TE K+K L
Sbjct: 919  VKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNL 978

Query: 977  EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
             EE   L++   KL KEKK L++   +   +L  EE+K  +L K K K E  + DLE  L
Sbjct: 979  TEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSL 1038

Query: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
             +E+K R +LE+ +RKLEGD     + I +L+    +L  +L KK+ EL A  AR+E+E 
Sbjct: 1039 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQ 1098

Query: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
            A  +   KK++EL+++I EL+E+LE+ER +R K EK + DL  ELE +   LE+   +T+
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158

Query: 1157 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216
             Q E+  KRE E   +++ LEE    HEA    +R+KH+ +V EL EQ++  +RVK  LE
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218

Query: 1217 KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276
            K K   + E  ++ + ++ +++ K + E   + +E Q+ E + K  E +R   +L  +  
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRA 1278

Query: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336
            KLQ E   ++  L + ++  S+LT+       QL+D +  L+EE + K +L+  L+    
Sbjct: 1279 KLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH 1338

Query: 1337 EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKDLE 1395
            + +  REQ EEE EAK  L++ ++  +++VA  + K E D++   E  EE K+KL + L+
Sbjct: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1398

Query: 1396 GLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
               +  E   A    LEKTK RLQ E++DL+VD++    +A  L+KKQ+ FD++LAE K 
Sbjct: 1399 EAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458

Query: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDD 1515
               +   E + ++ EAR   T+   L  A EE++E     +R NK  + E+ DL      
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGS 1518

Query: 1516 VGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
             GK++HELEK ++ LE +  E+++ LEE E  L+  E   LR ++    +KA+ ER L  
Sbjct: 1519 SGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1578

Query: 1576 RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDE 1635
            +DE+ E+ K+  +R V  ++  L+ E + R+ A+  +KK+E DL ++E  +  AN+   E
Sbjct: 1579 KDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638

Query: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
            A KQ++ LQ+ +KD   +LDD   + +++       E++   ++AE+ +L+  +   ER+
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698

Query: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
            ++ A+QE  E ++ +     +    + +K++++A ++QL+ E+EE         ++ KKA
Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758

Query: 1756 NLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK 1815
                  +  +L  E+  +   E  ++ +E+  K+L+ +L E E       K  +  LEA+
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818

Query: 1816 IAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQL 1875
            + +LE +L+ E K    + K +R++E+++K++  Q +++R+N  + +D  DK   ++K  
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878

Query: 1876 KRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            KRQ EEAEE+A    +  RK+Q EL++A E AD    +V+ L+ K R
Sbjct: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925



 Score =  249 bits (636), Expect = 2e-65
 Identities = 212/935 (22%), Positives = 436/935 (46%), Gaps = 59/935 (6%)

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAEL 1067
            L +  E+ K +A +K +     T L+E L + E +R+ELE+    L  +  DL  Q+   
Sbjct: 839  LLKSAEREKEMASMKEE----FTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 894

Query: 1068 QAQIAELKM---QLAKKEEELQAALA----RVEEEAAQKNMALKKIRELESQISELQEDL 1120
            Q  +A+ +    QL K + +L+A +     R+E+E         K R+LE + SEL+ D+
Sbjct: 895  QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954

Query: 1121 ESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA 1180
            +    +  K EK+K        A + ++++  +  A   E+ +K  +E    KK L+E  
Sbjct: 955  DDLELTLAKVEKEKH-------ATENKVKNLTEEMAGLDEIIAKLTKE----KKALQEA- 1002

Query: 1181 KTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGK 1240
                         H QA+++L  + ++   +     K +Q +++  G L  E KV +   
Sbjct: 1003 -------------HQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM--- 1046

Query: 1241 GDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLT 1300
             D E  ++K+E  L+  Q    + E  + +L +++ K   EL+ +   +    +  S+L 
Sbjct: 1047 -DLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQ 1105

Query: 1301 KDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIA 1360
            K    L++++++ +E L+ E   +  +      +  E     E+LEE   A     +   
Sbjct: 1106 KKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNK 1165

Query: 1361 TLHAQVADMKKKMEDSVGCLE-TAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQ 1419
               A+   M++ +E++    E TA  +++K    +  L ++ +       KLEK K+  +
Sbjct: 1166 KREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 1225

Query: 1420 QELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL 1479
             ELDD+  +++   ++  NLEK  +  +  + E ++ + +     +   ++  + +T+  
Sbjct: 1226 LELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG 1285

Query: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
             L+R L+E     ++L R    +  ++EDL    ++  K+ + L  + ++     + ++ 
Sbjct: 1286 ELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLRE 1345

Query: 1540 QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1599
            Q EE  +     +    +    +   + ++E D   R E+ EE KK+L ++++E E  +E
Sbjct: 1346 QYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVE 1405

Query: 1600 DERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRA 1659
                + S     + +L+ +++DL   ++ +N       K+ R          + L + + 
Sbjct: 1406 AVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD-------KILAEWKQ 1458

Query: 1660 SREEILAQAKENEKKLKSMEAEMIQL----QEELAAAERAKRQAQQERDELAD--EIANS 1713
              EE  ++ + ++K+ +S+  E+ +L    +E L   E  KR+ +  ++E++D  E   S
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGS 1518

Query: 1714 SGKGALALEEKRR-LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSH 1772
            SGK    LE+ R+ LEA   +L+  LEE + + E    ++ +A L+ +QI  ++  ER  
Sbjct: 1519 SGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKL 1576

Query: 1773 AQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITA--LEAKIAQLEEQLDNETKER 1830
            A+K+E   Q      + +      ++   +S+ +A      +E  + ++E QL +  +  
Sbjct: 1577 AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMA 1636

Query: 1831 QAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRAN 1890
              A KQV+  +  LKD  +Q+DD  R  +  K+       R   L+ +LEE     ++  
Sbjct: 1637 AEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE 1696

Query: 1891 ASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
             SR+  ++EL + +E    ++ + +SL N+ ++ D
Sbjct: 1697 RSRKLAEQELIETSERVQLLHSQNTSLINQKKKMD 1731



 Score =  189 bits (481), Expect = 2e-47
 Identities = 208/872 (23%), Positives = 373/872 (42%), Gaps = 122/872 (13%)

Query: 852  EELVKVREKQLAAEN-RLTEMETLQSQLMAEKLQLQ-------EQLQAETELCAEAEELR 903
            +E +K ++ +L A N R+ + + L SQL  +  +LQ       E+L+AE    A+ E+LR
Sbjct: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLR 1136

Query: 904  ARLTAKKQELEEICHDLEA----------------------RVEEEEERCQH---LQAEK 938
            + L+   +ELEEI   LE                       R + EE   QH     A +
Sbjct: 1137 SDLS---RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR 1193

Query: 939  KKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE--EQII------------LE 984
            KK   ++ EL EQ++  +  +QKL+ EK   + +L  +    EQII            LE
Sbjct: 1194 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLE 1253

Query: 985  DQNCK--------------LAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMIT 1030
            DQ  +              L  ++  L+    E +  L E+E     L + K  +   + 
Sbjct: 1254 DQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 1313

Query: 1031 DLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA 1090
            DL+ +L  E K +  L    +    D   L +Q  E     AEL+  L+K   E+     
Sbjct: 1314 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373

Query: 1091 RVEEEAAQKNMALKKIRE-LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELE 1149
            + E +A Q+   L++ ++ L  ++ E +E +E+  A  +  EK K  L  E+E L  ++E
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1433

Query: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ------KHSQAVEELAE 1203
             +  + AA  + +   ++ +   K+  EE     E+  +E R       K   A EE  E
Sbjct: 1434 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1493

Query: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263
             LE  KR   NL++    L  + G     +  L       E  RK++EA+  ELQ    E
Sbjct: 1494 HLETFKRENKNLQEEISDLTEQLGSSGKTIHEL-------EKVRKQLEAEKMELQSALEE 1546

Query: 1264 GERVRTELADKVTKLQVELDNVTG----LLSQSDSKSSKLTKDFSALESQLQDTQELLQE 1319
             E        K+ + Q+E + +       L++ D +  +  ++   +   LQ +   L  
Sbjct: 1547 AEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LDA 1603

Query: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379
            E R +       K++E + N    QL          +KQ+ +L + + D + +++D+V  
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663

Query: 1380 LETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL 1439
             +  +E    +++    L    EE  A  ++ E+++   +QEL +    +        +L
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723

Query: 1440 EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLN 1499
              ++KK D  L++ +T   +  +E   AE +A++  T A  +A  L++  +  A LER+ 
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1783

Query: 1500 KQFRTEMEDLMSSKDDV-------GKS--------VHELE--------------KSKRAL 1530
            K     ++DL    D+        GK         V ELE              K  R  
Sbjct: 1784 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1843

Query: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
            E++++E+  Q EE    L   +D   +L++ ++A K Q E        ++EE+    + +
Sbjct: 1844 ERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE--------EAEEQANTNLSK 1895

Query: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDL 1622
             R+++ EL++  ++  +A +   KL    +D+
Sbjct: 1896 FRKVQHELDEAEERADIAESQVNKLRAKSRDI 1927



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 92/341 (26%), Positives = 161/341 (47%), Gaps = 39/341 (11%)

Query: 833  KVKPLLQVSRQEEEMMAKEEELVKVR--------EKQLAAENRLT-----EMETLQSQLM 879
            +V   LQ S   E     E   VK +        E QL+  NR+      ++++LQS L 
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651

Query: 880  AEKLQLQEQLQAETEL---CAEAEELRARLTAKKQELEEICHDLEA--RVEEEE-----E 929
              ++QL + ++A  +L    A  E     L A+ +EL  +    E   ++ E+E     E
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1711

Query: 930  RCQHLQAE-------KKKMQQNIQELEEQLEE--EESARQKLQLEKVTTEAKL--KKLEE 978
            R Q L ++       KKKM  ++ +L+ ++EE  +E    + + +K  T+A +  ++L++
Sbjct: 1712 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1771

Query: 979  EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS-KSLAKLKNKHEAMITDLEERLR 1037
            EQ    D +  L + KK +E  I +    L E E+ + K   K   K EA + +LE  L 
Sbjct: 1772 EQ----DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1827

Query: 1038 REEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAA 1097
             E+K+  E  K  RK E    +L+ Q  E +  +  L+  + K + +++A   + EE   
Sbjct: 1828 AEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1887

Query: 1098 QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLG 1138
            Q N  L K R+++ ++ E +E  +   +  NK   + RD+G
Sbjct: 1888 QANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIG 1928


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 1410 bits (3651), Expect = 0.0
 Identities = 771/1909 (40%), Positives = 1179/1909 (61%), Gaps = 25/1909 (1%)

Query: 28   AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
            AK  V+V   K  F   +++   G +  V+  E G  + V  D +  MNPPK+ K+EDMA
Sbjct: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92

Query: 88   ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
             +T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y  E+V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152

Query: 148  PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203
            PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+    
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212

Query: 204  ---QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLE 260
               QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLE
Sbjct: 213  GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272

Query: 261  KSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDM 318
            KSR + Q K ER++HIFY + S     L   LL+   PY+ Y F+S G +++    D++ 
Sbjct: 273  KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYD-YPFVSQGEISVASIDDQEE 331

Query: 319  FQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLL 378
               T  A+ I+G   EE++ + ++   V+  GN+ FK+++  +QA       A K ++L 
Sbjct: 332  LMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQ 391

Query: 379  GINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD 438
             +N  D  + +  PR+KVG +YV K QT EQ   A+ ALAKA YE+MF W+V RIN+ LD
Sbjct: 392  SLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD 451

Query: 439  KTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 498
             TK+    FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIE
Sbjct: 452  -TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510

Query: 499  WNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQ 557
            W FIDFG+DL  CI+LIEKP G   I ++L+EEC FPKATD SF  K+  Q  G    FQ
Sbjct: 511  WTFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567

Query: 558  KPKQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDV 615
            KPK +K KA+  F +IHYAG VDY    WL KN DPLN+ +  L  +S+ K +++L+   
Sbjct: 568  KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGA 627

Query: 616  DRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675
                G     G  +       K +   F+TV  L++E L KLM  LR+T+P+FVRCIIPN
Sbjct: 628  QTAEGEGAGGGAKKGG-----KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 682

Query: 676  HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FM 734
              K  G ++  LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L  ++IP+G F+
Sbjct: 683  ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 742

Query: 735  DGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYL 794
            D K+A   ++ ++++D   Y+ G +KVFF+AG+L  LEE RD K+  +I   QA CRG+L
Sbjct: 743  DSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFL 802

Query: 795  ARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEEL 854
            AR  + +  ++  A+  +Q N  +++ +++W W +LF K+KPLL+ +  E+EM   +EE 
Sbjct: 803  ARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 862

Query: 855  VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE 914
             K++++   +E +  E+E     L+ EK  LQ Q+QAE E  A+AEE   +L   K +LE
Sbjct: 863  QKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLE 922

Query: 915  EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974
                ++  R E+EEE    L A+K+K++    EL++ +++ E    K++ EK  TE K+K
Sbjct: 923  AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 982

Query: 975  KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
             L EE   L++   KL KEKK L++   +   +L  EE+K  +L K K K E  + DLE 
Sbjct: 983  NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1042

Query: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1094
             L +E+K R +LE+ +RKLEGD     + I +++ +  +L  +L KKE E+    +++E+
Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102

Query: 1095 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154
            E A      KKI+EL+++I EL+E++E+ERASR KAEKQ+ DL  ELE +   LE+   +
Sbjct: 1103 EQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1162

Query: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
            T+AQ E+  KRE E   +++ LEE    HEA    +R+KH+ +V EL EQ++  +RVK  
Sbjct: 1163 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222

Query: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
            LEK K  ++ E  +LA+ V+ + + KG+ E   + +E QL EL+ K  E +R+  +L  +
Sbjct: 1223 LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ 1282

Query: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
              +LQ E    +  L + ++  S+L++   A   Q+++ +  L+EE + K +L+  L+  
Sbjct: 1283 RGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSS 1342

Query: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKD 1393
              + +  REQ EEE+E+K  L++ ++  + +VA  + K E D++   E  EE K+KL + 
Sbjct: 1343 RHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402

Query: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453
            L+   +  E   A    LEKTK RLQ E++DL++D++    +   L+KKQ+ FD++LAE 
Sbjct: 1403 LQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462

Query: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513
            K    +   E + ++ EAR   T+   +  A EE+++Q   L+R NK  + E+ DL    
Sbjct: 1463 KQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1522

Query: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573
             + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ L  +K++ +R +
Sbjct: 1523 AEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1582

Query: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633
              +DE+ ++ K+  +R V  M++ L+ E + R+ A+  +KK+E DL ++E  ++ AN+  
Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642

Query: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693
             EA++  R  Q  +KD    LDD   S+E++  Q    E++   ++AE+ +L+  L   E
Sbjct: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702

Query: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK 1753
            R+++ A+QE  + ++ +     +    +  K++LE  I+Q++ E+E+         ++ K
Sbjct: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAK 1762

Query: 1754 KANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALE 1813
            KA      +  +L  E+  +   E  ++ +E+  K+L+++L E E       K  I  LE
Sbjct: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLE 1822

Query: 1814 AKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLK 1873
            A++ +LE ++++E K    A K +R+ E+++K++  Q +++R+N  + +D  DK   ++K
Sbjct: 1823 ARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1882

Query: 1874 QLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
              KRQ EEAEE++    A  RKLQ ELE+A E AD    +V+ L+ K R
Sbjct: 1883 SYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931



 Score =  255 bits (651), Expect = 3e-67
 Identities = 224/937 (23%), Positives = 447/937 (47%), Gaps = 67/937 (7%)

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI--- 1064
            L +  E  K +A +K + +     +++ L + E +R+ELE+    L  +  DL  Q+   
Sbjct: 845  LLKSAETEKEMATMKEEFQK----IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900

Query: 1065 AELQAQIAELKMQLAKKEEELQAALARV-----EEEAAQKNMALKKIRELESQISELQED 1119
            AE  A   E   QL K + +L+A +  V     +EE     +  KK R+LE + SEL++D
Sbjct: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKD 959

Query: 1120 LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE-- 1177
            ++    +  K EK+K     +++ L  E+   LD T A+     K  QE +  ++TL+  
Sbjct: 960  IDDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKLTKEKKALQEAH--QQTLDDL 1016

Query: 1178 --EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
              EE K +   + + + K  Q V++L   LEQ K+++ +LE+AK+ LE +       +  
Sbjct: 1017 QAEEDKVNT--LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMD 1074

Query: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295
            +   K   + K KK E ++  LQ K  + + +  +L  K+ +LQ  ++ +   +    + 
Sbjct: 1075 IENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERAS 1134

Query: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNL 1355
             +K  K  S L  +L++  E L+E      +     K+ E E    R  LEE        
Sbjct: 1135 RAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE-------- 1186

Query: 1356 EKQIATLH--AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK 1413
                ATL   A  A ++KK  DSV   E  E++      +L+ + Q          KLEK
Sbjct: 1187 ----ATLQHEATAATLRKKHADSVA--ELGEQID-----NLQRVKQ----------KLEK 1225

Query: 1414 TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE 1473
             K+ ++ E+DDL  +++   ++  NLEK  +  +  L+E K+   +     +   A+   
Sbjct: 1226 EKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR 1285

Query: 1474 KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
             +T++   +R L+E     ++L R  + F  ++E+L    ++  K+ + L  + ++    
Sbjct: 1286 LQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345

Query: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
             + ++ Q EE ++     + A  +    +   + ++E D   R E+ EE KK+L ++++ 
Sbjct: 1346 CDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQA 1405

Query: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
             E  +E    + +     +++L+ +++DL   ++  N       K+ R     + +  ++
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465

Query: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
             ++T A  E    +A+    +L  ++    +  ++L   +R  +  QQE  +L ++IA  
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525

Query: 1714 SGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSH 1772
             GK    LE+ K+++E    +L+  LEE + + E    ++ +  L+++Q+ +++  +R  
Sbjct: 1526 -GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKI 1582

Query: 1773 AQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNE 1826
            A+K+E    QL+R +  +   ++ M+ T+ ++ ++   A+  K      + ++E QL++ 
Sbjct: 1583 AEKDEEI-DQLKRNHIRI---VESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1638

Query: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
             +    A +  R T+  LKD  + +DD  R+ E  K+Q      R   L+ ++EE     
Sbjct: 1639 NRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1698

Query: 1887 QRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
            ++   SR+  ++EL DA+E    ++ + +SL N  ++
Sbjct: 1699 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735



 Score =  217 bits (552), Expect = 1e-55
 Identities = 208/960 (21%), Positives = 446/960 (46%), Gaps = 120/960 (12%)

Query: 832  TKVKPLLQVSRQE--EEMMAKEEELVKVREKQLAAENRLTEME-------TLQSQLMAEK 882
            TK K  LQ + Q+  +++ A+E+++  + + ++  E ++ ++E        L+  L   K
Sbjct: 999  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058

Query: 883  LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
             +L+  L+   E   + E  + +L  K ++ E    +L++++E+E+     LQ + K++Q
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118

Query: 943  QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
              I+ELEE++E E ++R K + ++     +L+++ E    LE+     + + ++ + R A
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQIEMNKKREA 1175

Query: 1003 EFTTNLTEEEEKS----KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
            EF     + EE +     + A L+ KH   + +L E++   ++ +Q+LEK + +++ +  
Sbjct: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235

Query: 1059 DLSDQIAE--------------LQAQIAELKMQLAKKEE---ELQAALARVEEEAAQKNM 1101
            DL+  +                L+ Q++ELK +  +++    +L A   R++ E+ + + 
Sbjct: 1236 DLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSR 1295

Query: 1102 ALKKIRELESQIS-----------ELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
             L +   L SQ+S           EL+  LE E  ++N      +    + + L+ + E+
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355

Query: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210
              +S A  Q   SK   EV   +   E +A     +++E ++K +Q ++   E +E    
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415

Query: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
              A+LEK KQ L+NE  +L  +V+         + K++  +  L E + K  E       
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475

Query: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
               +   L  EL  +     +S  +   L ++   L+ ++ D  E + E  ++   L   
Sbjct: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1535

Query: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL-ETAEEVKRK 1389
             KQVE EK   +  LEE E +  + E +I  +  ++  +K +++  +    E  +++KR 
Sbjct: 1536 KKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1595

Query: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449
              + +E +    + ++ + +   + K +++ +L+++ + L+H  + A    +  +    +
Sbjct: 1596 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGI 1655

Query: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQ-KAELERLNKQFRTEMED 1508
            L + +     + ++  R++ + +E+       A  L+  +E+ +A LE+  +  +   ++
Sbjct: 1656 LKDTQI----HLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQE 1711

Query: 1509 LMSSKDDVGKSVH----ELEKSKRALEQQVEEMKTQLEELEDELQATE--------DAKL 1556
            L+ + + V + +H     L  +K+ LE  + +M+ ++E++  E +  E        DA +
Sbjct: 1712 LLDASERV-QLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAM 1770

Query: 1557 RLE---------VNLQAMKAQFE---RDLQGRDEQSEEK-----KKQLVR---QVREMEA 1596
              E          +L+ MK   E   +DLQ R +++E+      KKQ+ +   +VRE+E 
Sbjct: 1771 MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEG 1830

Query: 1597 ELEDERKQRSMAVAARKKLEMDLKDL---------------------EAHIDSANKNRDE 1635
            E+E E+K+ + AV   +K E  +K+L                     +A + S  +  +E
Sbjct: 1831 EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1890

Query: 1636 AIKQ-------LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
            A +Q        RKLQ ++++     D         +A+++ N+ ++KS E     + EE
Sbjct: 1891 AEEQSNTNLAKFRKLQHELEEAEERAD---------IAESQVNKLRVKSREVHTKVISEE 1941



 Score =  152 bits (383), Expect = 4e-36
 Identities = 147/646 (22%), Positives = 294/646 (45%), Gaps = 51/646 (7%)

Query: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
            KS++  K+ + ++ + Q  ++ L +   ++  L  K+  +  EKN  + Q++ E E   +
Sbjct: 847  KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906

Query: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
             E++   L      ++ K+++     E  EE+  +L               A   KLE  
Sbjct: 907  AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAEL--------------TAKKRKLEDE 952

Query: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
             + L++++DDL + L    +     E K K   + +A      AK  +E+ +A  EA ++
Sbjct: 953  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK-KALQEAHQQ 1011

Query: 1475 ETKALSLARALEEAMEQKAE-LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
                L       +A E K   L +   +   +++DL  S +   K   +LE++KR LE  
Sbjct: 1012 TLDDL-------QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD 1064

Query: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
            ++  +  + ++E+E Q  ++   + E  +  ++++ E D Q    Q ++K K+L  ++ E
Sbjct: 1065 LKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIE-DEQALGIQLQKKIKELQARIEE 1123

Query: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
            +E E+E ER  R+ A   R  L  +L+++   ++ A       I+  +K +A+ +   R+
Sbjct: 1124 LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD 1183

Query: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
            L++     E   A  +      K     + +L E++   +R K++ ++E+ E+  EI + 
Sbjct: 1184 LEEATLQHEATAATLR------KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1237

Query: 1714 SGKGALALEEKRRLEARIAQLEEELEE----EQGNTELIND-RLKKANLQIDQINTDLNL 1768
            +       + K  LE     LE++L E    E+    LIND   ++  LQ +       L
Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL 1297

Query: 1769 ERSHAQKNENAR--QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNE 1826
            +   A  ++ +R  Q   +Q +ELK +L+E    +K+K  A   AL++     +   +  
Sbjct: 1298 DEKEALVSQLSRGKQAFTQQIEELKRQLEE---EIKAK-NALAHALQSSRHDCDLLREQY 1353

Query: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
             +E+++  +  R   K   +V         +A Q  ++ ++A    K+L ++L+ AEE  
Sbjct: 1354 EEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQAAEEHV 1410

Query: 1887 QRANA-------SRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
            +  NA       ++++LQ E+ED     +  N   ++L  K R  D
Sbjct: 1411 EAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 75/379 (19%), Positives = 167/379 (44%), Gaps = 33/379 (8%)

Query: 1555 KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKK 1614
            KL  ++      A+ E+++    E+ ++ K +L +     EA+ ++  ++    +  +  
Sbjct: 837  KLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKS----EAKRKELEEKMVTLLKEKND 892

Query: 1615 LEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK 1674
            L++ ++     +  A +  D+ IK   +L+A++K+     +D      E+ A+ ++ E +
Sbjct: 893  LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 952

Query: 1675 LKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQL 1734
               ++ ++  L+  LA  E+ K   + +   L +E+A      A   +EK+ L+    Q 
Sbjct: 953  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT 1012

Query: 1735 EEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1794
             ++L+ E+     +     K   Q+D +   L  E+         R  LER  ++L    
Sbjct: 1013 LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKK-------LRMDLERAKRKL---- 1061

Query: 1795 QEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDE 1854
               EG +K   + SI  +E +  QL+E+L              ++ E ++ ++  +++DE
Sbjct: 1062 ---EGDLKLAQE-SIMDIENEKQQLDEKL--------------KKKEFEISNLQSKIEDE 1103

Query: 1855 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREV 1914
            +    Q + +  +   R+++L+ ++E       +A   R  L RELE+ +E  +      
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163

Query: 1915 SSLKNKLRRGDLPFVVPRR 1933
            S+     ++ +  F   RR
Sbjct: 1164 SAQIEMNKKREAEFQKMRR 1182



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 69/332 (20%), Positives = 142/332 (42%), Gaps = 67/332 (20%)

Query: 1633 RDEAIKQL-RKLQAQMKDCMRELDDTR-ASREEILAQAKENEKKLKSME-----AEMIQL 1685
            RD+ + QL  + QA+ +  +  ++  R   R E +   + N +   +++         ++
Sbjct: 783  RDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKI 842

Query: 1686 QEELAAAERAKRQA--QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743
            +  L +AE  K  A  ++E  ++ DE+A S  K       ++ LE ++  L +E  + Q 
Sbjct: 843  KPLLKSAETEKEMATMKEEFQKIKDELAKSEAK-------RKELEEKMVTLLKEKNDLQL 895

Query: 1744 NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKS 1803
              +   + L  A  + DQ+                 + QLE + KE+  + ++ E     
Sbjct: 896  QVQAEAEGLADAEERCDQLI--------------KTKIQLEAKIKEVTERAEDEE----- 936

Query: 1804 KYKASITA----LEAKIAQLEEQLDN-------ETKERQAACKQVR-------------- 1838
            +  A +TA    LE + ++L++ +D+         KE+ A   +V+              
Sbjct: 937  EINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIA 996

Query: 1839 ---RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ----LKRQLEEAEEEAQRANA 1891
               + +K L++   Q  D+ +  E   +   KA  +L+Q    L+  LE+ ++       
Sbjct: 997  KLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLER 1056

Query: 1892 SRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
            ++RKL+ +L+ A E+   +  E   L  KL++
Sbjct: 1057 AKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 1410 bits (3651), Expect = 0.0
 Identities = 771/1909 (40%), Positives = 1179/1909 (61%), Gaps = 25/1909 (1%)

Query: 28   AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
            AK  V+V   K  F   +++   G +  V+  E G  + V  D +  MNPPK+ K+EDMA
Sbjct: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92

Query: 88   ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
             +T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y  E+V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152

Query: 148  PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203
            PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+    
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212

Query: 204  ---QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLE 260
               QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLE
Sbjct: 213  GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272

Query: 261  KSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDM 318
            KSR + Q K ER++HIFY + S     L   LL+   PY+ Y F+S G +++    D++ 
Sbjct: 273  KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYD-YPFVSQGEISVASIDDQEE 331

Query: 319  FQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLL 378
               T  A+ I+G   EE++ + ++   V+  GN+ FK+++  +QA       A K ++L 
Sbjct: 332  LMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQ 391

Query: 379  GINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD 438
             +N  D  + +  PR+KVG +YV K QT EQ   A+ ALAKA YE+MF W+V RIN+ LD
Sbjct: 392  SLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD 451

Query: 439  KTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 498
             TK+    FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIE
Sbjct: 452  -TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510

Query: 499  WNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQ 557
            W FIDFG+DL  CI+LIEKP G   I ++L+EEC FPKATD SF  K+  Q  G    FQ
Sbjct: 511  WTFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567

Query: 558  KPKQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDV 615
            KPK +K KA+  F +IHYAG VDY    WL KN DPLN+ +  L  +S+ K +++L+   
Sbjct: 568  KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGA 627

Query: 616  DRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675
                G     G  +       K +   F+TV  L++E L KLM  LR+T+P+FVRCIIPN
Sbjct: 628  QTAEGEGAGGGAKKGG-----KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 682

Query: 676  HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FM 734
              K  G ++  LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L  ++IP+G F+
Sbjct: 683  ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 742

Query: 735  DGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYL 794
            D K+A   ++ ++++D   Y+ G +KVFF+AG+L  LEE RD K+  +I   QA CRG+L
Sbjct: 743  DSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFL 802

Query: 795  ARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEEL 854
            AR  + +  ++  A+  +Q N  +++ +++W W +LF K+KPLL+ +  E+EM   +EE 
Sbjct: 803  ARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 862

Query: 855  VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE 914
             K++++   +E +  E+E     L+ EK  LQ Q+QAE E  A+AEE   +L   K +LE
Sbjct: 863  QKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLE 922

Query: 915  EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974
                ++  R E+EEE    L A+K+K++    EL++ +++ E    K++ EK  TE K+K
Sbjct: 923  AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 982

Query: 975  KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
             L EE   L++   KL KEKK L++   +   +L  EE+K  +L K K K E  + DLE 
Sbjct: 983  NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1042

Query: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1094
             L +E+K R +LE+ +RKLEGD     + I +++ +  +L  +L KKE E+    +++E+
Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIED 1102

Query: 1095 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154
            E A      KKI+EL+++I EL+E++E+ERASR KAEKQ+ DL  ELE +   LE+   +
Sbjct: 1103 EQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1162

Query: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
            T+AQ E+  KRE E   +++ LEE    HEA    +R+KH+ +V EL EQ++  +RVK  
Sbjct: 1163 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222

Query: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
            LEK K  ++ E  +LA+ V+ + + KG+ E   + +E QL EL+ K  E +R+  +L  +
Sbjct: 1223 LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ 1282

Query: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
              +LQ E    +  L + ++  S+L++   A   Q+++ +  L+EE + K +L+  L+  
Sbjct: 1283 RGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSS 1342

Query: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKD 1393
              + +  REQ EEE+E+K  L++ ++  + +VA  + K E D++   E  EE K+KL + 
Sbjct: 1343 RHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402

Query: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453
            L+   +  E   A    LEKTK RLQ E++DL++D++    +   L+KKQ+ FD++LAE 
Sbjct: 1403 LQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462

Query: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513
            K    +   E + ++ EAR   T+   +  A EE+++Q   L+R NK  + E+ DL    
Sbjct: 1463 KQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1522

Query: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573
             + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ L  +K++ +R +
Sbjct: 1523 AEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1582

Query: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633
              +DE+ ++ K+  +R V  M++ L+ E + R+ A+  +KK+E DL ++E  ++ AN+  
Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642

Query: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693
             EA++  R  Q  +KD    LDD   S+E++  Q    E++   ++AE+ +L+  L   E
Sbjct: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702

Query: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK 1753
            R+++ A+QE  + ++ +     +    +  K++LE  I+Q++ E+E+         ++ K
Sbjct: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAK 1762

Query: 1754 KANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALE 1813
            KA      +  +L  E+  +   E  ++ +E+  K+L+++L E E       K  I  LE
Sbjct: 1763 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLE 1822

Query: 1814 AKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLK 1873
            A++ +LE ++++E K    A K +R+ E+++K++  Q +++R+N  + +D  DK   ++K
Sbjct: 1823 ARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1882

Query: 1874 QLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
              KRQ EEAEE++    A  RKLQ ELE+A E AD    +V+ L+ K R
Sbjct: 1883 SYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931



 Score =  255 bits (651), Expect = 3e-67
 Identities = 224/937 (23%), Positives = 447/937 (47%), Gaps = 67/937 (7%)

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI--- 1064
            L +  E  K +A +K + +     +++ L + E +R+ELE+    L  +  DL  Q+   
Sbjct: 845  LLKSAETEKEMATMKEEFQK----IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900

Query: 1065 AELQAQIAELKMQLAKKEEELQAALARV-----EEEAAQKNMALKKIRELESQISELQED 1119
            AE  A   E   QL K + +L+A +  V     +EE     +  KK R+LE + SEL++D
Sbjct: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKD 959

Query: 1120 LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE-- 1177
            ++    +  K EK+K     +++ L  E+   LD T A+     K  QE +  ++TL+  
Sbjct: 960  IDDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKLTKEKKALQEAH--QQTLDDL 1016

Query: 1178 --EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
              EE K +   + + + K  Q V++L   LEQ K+++ +LE+AK+ LE +       +  
Sbjct: 1017 QAEEDKVNT--LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMD 1074

Query: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295
            +   K   + K KK E ++  LQ K  + + +  +L  K+ +LQ  ++ +   +    + 
Sbjct: 1075 IENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERAS 1134

Query: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNL 1355
             +K  K  S L  +L++  E L+E      +     K+ E E    R  LEE        
Sbjct: 1135 RAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE-------- 1186

Query: 1356 EKQIATLH--AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK 1413
                ATL   A  A ++KK  DSV   E  E++      +L+ + Q          KLEK
Sbjct: 1187 ----ATLQHEATAATLRKKHADSVA--ELGEQID-----NLQRVKQ----------KLEK 1225

Query: 1414 TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE 1473
             K+ ++ E+DDL  +++   ++  NLEK  +  +  L+E K+   +     +   A+   
Sbjct: 1226 EKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGR 1285

Query: 1474 KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
             +T++   +R L+E     ++L R  + F  ++E+L    ++  K+ + L  + ++    
Sbjct: 1286 LQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345

Query: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
             + ++ Q EE ++     + A  +    +   + ++E D   R E+ EE KK+L ++++ 
Sbjct: 1346 CDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQA 1405

Query: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
             E  +E    + +     +++L+ +++DL   ++  N       K+ R     + +  ++
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465

Query: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
             ++T A  E    +A+    +L  ++    +  ++L   +R  +  QQE  +L ++IA  
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525

Query: 1714 SGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSH 1772
             GK    LE+ K+++E    +L+  LEE + + E    ++ +  L+++Q+ +++  +R  
Sbjct: 1526 -GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKI 1582

Query: 1773 AQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNE 1826
            A+K+E    QL+R +  +   ++ M+ T+ ++ ++   A+  K      + ++E QL++ 
Sbjct: 1583 AEKDEEI-DQLKRNHIRI---VESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1638

Query: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
             +    A +  R T+  LKD  + +DD  R+ E  K+Q      R   L+ ++EE     
Sbjct: 1639 NRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1698

Query: 1887 QRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
            ++   SR+  ++EL DA+E    ++ + +SL N  ++
Sbjct: 1699 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735



 Score =  217 bits (552), Expect = 1e-55
 Identities = 208/960 (21%), Positives = 446/960 (46%), Gaps = 120/960 (12%)

Query: 832  TKVKPLLQVSRQE--EEMMAKEEELVKVREKQLAAENRLTEME-------TLQSQLMAEK 882
            TK K  LQ + Q+  +++ A+E+++  + + ++  E ++ ++E        L+  L   K
Sbjct: 999  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058

Query: 883  LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
             +L+  L+   E   + E  + +L  K ++ E    +L++++E+E+     LQ + K++Q
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118

Query: 943  QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
              I+ELEE++E E ++R K + ++     +L+++ E    LE+     + + ++ + R A
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQIEMNKKREA 1175

Query: 1003 EFTTNLTEEEEKS----KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
            EF     + EE +     + A L+ KH   + +L E++   ++ +Q+LEK + +++ +  
Sbjct: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235

Query: 1059 DLSDQIAE--------------LQAQIAELKMQLAKKEE---ELQAALARVEEEAAQKNM 1101
            DL+  +                L+ Q++ELK +  +++    +L A   R++ E+ + + 
Sbjct: 1236 DLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSR 1295

Query: 1102 ALKKIRELESQIS-----------ELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
             L +   L SQ+S           EL+  LE E  ++N      +    + + L+ + E+
Sbjct: 1296 QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE 1355

Query: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210
              +S A  Q   SK   EV   +   E +A     +++E ++K +Q ++   E +E    
Sbjct: 1356 EQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNA 1415

Query: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
              A+LEK KQ L+NE  +L  +V+         + K++  +  L E + K  E       
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475

Query: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
               +   L  EL  +     +S  +   L ++   L+ ++ D  E + E  ++   L   
Sbjct: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1535

Query: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL-ETAEEVKRK 1389
             KQVE EK   +  LEE E +  + E +I  +  ++  +K +++  +    E  +++KR 
Sbjct: 1536 KKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1595

Query: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449
              + +E +    + ++ + +   + K +++ +L+++ + L+H  + A    +  +    +
Sbjct: 1596 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGI 1655

Query: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQ-KAELERLNKQFRTEMED 1508
            L + +     + ++  R++ + +E+       A  L+  +E+ +A LE+  +  +   ++
Sbjct: 1656 LKDTQI----HLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQE 1711

Query: 1509 LMSSKDDVGKSVH----ELEKSKRALEQQVEEMKTQLEELEDELQATE--------DAKL 1556
            L+ + + V + +H     L  +K+ LE  + +M+ ++E++  E +  E        DA +
Sbjct: 1712 LLDASERV-QLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAM 1770

Query: 1557 RLE---------VNLQAMKAQFE---RDLQGRDEQSEEK-----KKQLVR---QVREMEA 1596
              E          +L+ MK   E   +DLQ R +++E+      KKQ+ +   +VRE+E 
Sbjct: 1771 MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEG 1830

Query: 1597 ELEDERKQRSMAVAARKKLEMDLKDL---------------------EAHIDSANKNRDE 1635
            E+E E+K+ + AV   +K E  +K+L                     +A + S  +  +E
Sbjct: 1831 EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1890

Query: 1636 AIKQ-------LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
            A +Q        RKLQ ++++     D         +A+++ N+ ++KS E     + EE
Sbjct: 1891 AEEQSNTNLAKFRKLQHELEEAEERAD---------IAESQVNKLRVKSREVHTKVISEE 1941



 Score =  152 bits (383), Expect = 4e-36
 Identities = 147/646 (22%), Positives = 294/646 (45%), Gaps = 51/646 (7%)

Query: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
            KS++  K+ + ++ + Q  ++ L +   ++  L  K+  +  EKN  + Q++ E E   +
Sbjct: 847  KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906

Query: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
             E++   L      ++ K+++     E  EE+  +L               A   KLE  
Sbjct: 907  AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAEL--------------TAKKRKLEDE 952

Query: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
             + L++++DDL + L    +     E K K   + +A      AK  +E+ +A  EA ++
Sbjct: 953  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK-KALQEAHQQ 1011

Query: 1475 ETKALSLARALEEAMEQKAE-LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
                L       +A E K   L +   +   +++DL  S +   K   +LE++KR LE  
Sbjct: 1012 TLDDL-------QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD 1064

Query: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
            ++  +  + ++E+E Q  ++   + E  +  ++++ E D Q    Q ++K K+L  ++ E
Sbjct: 1065 LKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIE-DEQALGIQLQKKIKELQARIEE 1123

Query: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
            +E E+E ER  R+ A   R  L  +L+++   ++ A       I+  +K +A+ +   R+
Sbjct: 1124 LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD 1183

Query: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
            L++     E   A  +      K     + +L E++   +R K++ ++E+ E+  EI + 
Sbjct: 1184 LEEATLQHEATAATLR------KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1237

Query: 1714 SGKGALALEEKRRLEARIAQLEEELEE----EQGNTELIND-RLKKANLQIDQINTDLNL 1768
            +       + K  LE     LE++L E    E+    LIND   ++  LQ +       L
Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL 1297

Query: 1769 ERSHAQKNENAR--QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNE 1826
            +   A  ++ +R  Q   +Q +ELK +L+E    +K+K  A   AL++     +   +  
Sbjct: 1298 DEKEALVSQLSRGKQAFTQQIEELKRQLEE---EIKAK-NALAHALQSSRHDCDLLREQY 1353

Query: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
             +E+++  +  R   K   +V         +A Q  ++ ++A    K+L ++L+ AEE  
Sbjct: 1354 EEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQAAEEHV 1410

Query: 1887 QRANA-------SRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
            +  NA       ++++LQ E+ED     +  N   ++L  K R  D
Sbjct: 1411 EAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 75/379 (19%), Positives = 167/379 (44%), Gaps = 33/379 (8%)

Query: 1555 KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKK 1614
            KL  ++      A+ E+++    E+ ++ K +L +     EA+ ++  ++    +  +  
Sbjct: 837  KLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKS----EAKRKELEEKMVTLLKEKND 892

Query: 1615 LEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK 1674
            L++ ++     +  A +  D+ IK   +L+A++K+     +D      E+ A+ ++ E +
Sbjct: 893  LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 952

Query: 1675 LKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQL 1734
               ++ ++  L+  LA  E+ K   + +   L +E+A      A   +EK+ L+    Q 
Sbjct: 953  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT 1012

Query: 1735 EEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1794
             ++L+ E+     +     K   Q+D +   L  E+         R  LER  ++L    
Sbjct: 1013 LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKK-------LRMDLERAKRKL---- 1061

Query: 1795 QEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDE 1854
               EG +K   + SI  +E +  QL+E+L              ++ E ++ ++  +++DE
Sbjct: 1062 ---EGDLKLAQE-SIMDIENEKQQLDEKL--------------KKKEFEISNLQSKIEDE 1103

Query: 1855 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREV 1914
            +    Q + +  +   R+++L+ ++E       +A   R  L RELE+ +E  +      
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163

Query: 1915 SSLKNKLRRGDLPFVVPRR 1933
            S+     ++ +  F   RR
Sbjct: 1164 SAQIEMNKKREAEFQKMRR 1182



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 69/332 (20%), Positives = 142/332 (42%), Gaps = 67/332 (20%)

Query: 1633 RDEAIKQL-RKLQAQMKDCMRELDDTR-ASREEILAQAKENEKKLKSME-----AEMIQL 1685
            RD+ + QL  + QA+ +  +  ++  R   R E +   + N +   +++         ++
Sbjct: 783  RDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKI 842

Query: 1686 QEELAAAERAKRQA--QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743
            +  L +AE  K  A  ++E  ++ DE+A S  K       ++ LE ++  L +E  + Q 
Sbjct: 843  KPLLKSAETEKEMATMKEEFQKIKDELAKSEAK-------RKELEEKMVTLLKEKNDLQL 895

Query: 1744 NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKS 1803
              +   + L  A  + DQ+                 + QLE + KE+  + ++ E     
Sbjct: 896  QVQAEAEGLADAEERCDQLI--------------KTKIQLEAKIKEVTERAEDEE----- 936

Query: 1804 KYKASITA----LEAKIAQLEEQLDN-------ETKERQAACKQVR-------------- 1838
            +  A +TA    LE + ++L++ +D+         KE+ A   +V+              
Sbjct: 937  EINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIA 996

Query: 1839 ---RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ----LKRQLEEAEEEAQRANA 1891
               + +K L++   Q  D+ +  E   +   KA  +L+Q    L+  LE+ ++       
Sbjct: 997  KLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLER 1056

Query: 1892 SRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
            ++RKL+ +L+ A E+   +  E   L  KL++
Sbjct: 1057 AKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 1410 bits (3651), Expect = 0.0
 Identities = 778/1912 (40%), Positives = 1180/1912 (61%), Gaps = 36/1912 (1%)

Query: 28   AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
            AK  V+V   K  +  ++++ + G +  V+  E G  + V +D +  MNPPK+ K+EDMA
Sbjct: 36   AKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMA 94

Query: 88   ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
             +T L+E  VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y  E+V  Y+GKKR E P
Sbjct: 95   MMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 154

Query: 148  PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203
            PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KKD    
Sbjct: 155  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGK 214

Query: 204  -QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKS 262
             QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLEKS
Sbjct: 215  MQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 274

Query: 263  RAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDMFQ 320
            R   Q K ER++HIFY + S     L   LL+   PY+ Y F+S G +T+P   D++   
Sbjct: 275  RVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYD-YAFVSQGEITVPSIDDQEELM 333

Query: 321  ETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGI 380
             T  A+ I+G   EE++ + ++   V+  GN+ FK+++  +QA       A K ++L  +
Sbjct: 334  ATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSL 393

Query: 381  NVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKT 440
            N  D  + +  PR+KVG +YV K QT +Q   A+ ALAKA YE+MF W+V RIN+ LD T
Sbjct: 394  NSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD-T 452

Query: 441  KRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 500
            K+    FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW 
Sbjct: 453  KQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 512

Query: 501  FIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQKP 559
            FIDFG+DL  CI+LIEKP G   I ++L+EEC FPKATD SF  K+  Q  G    FQKP
Sbjct: 513  FIDFGMDLAACIELIEKPLG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKP 569

Query: 560  KQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDR 617
            K +K KA+  F +IHYAG VDY    WL KN DPLND +  L  +S+ K ++ L+     
Sbjct: 570  KVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYAS 629

Query: 618  IIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHE 677
                   A    +A  GA K +   F+TV  L++E L KLM  LR+T+P+FVRCIIPN  
Sbjct: 630  -------AEADSSAKKGA-KKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 681

Query: 678  KKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDG 736
            K  G ++  LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L  ++IP+G F+D 
Sbjct: 682  KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDS 741

Query: 737  KQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLAR 796
            K+A   ++ ++++D   Y+ G +KVFF+AG+L  LEE RD K+  +I   QA CRG+L R
Sbjct: 742  KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMR 801

Query: 797  KAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVK 856
              + K  Q+  A+  +Q N  A++ +++W W +LF K+KPLL+ +  E+EM   +EE  K
Sbjct: 802  VEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQK 861

Query: 857  VREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEI 916
             +++   +E +  E+E     L+ EK  LQ Q+Q+E +  A+AEE   +L   K +LE  
Sbjct: 862  TKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAK 921

Query: 917  CHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKL 976
              ++  R EEEEE    L A+K+K++    EL++ +++ E    K++ EK  TE K+K L
Sbjct: 922  IKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 981

Query: 977  EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
             EE   L++   KL+KEKK L++   +   +L  EE+K   L K K K E  + DLE  L
Sbjct: 982  TEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSL 1041

Query: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
             +E+K R +LE+ +RKLEGD     +   +++    +L  +L KKE E+   ++++E+E 
Sbjct: 1042 EQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQ 1101

Query: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
            A +    KKI+EL+++I EL E++E+ERASR KAEKQ+ DL  ELE +   LE+   +T+
Sbjct: 1102 AVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS 1161

Query: 1157 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216
            AQ EL  KRE E   L++ LEE    HEA +  +R+KH+ ++ EL EQ++  +RVK  LE
Sbjct: 1162 AQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLE 1221

Query: 1217 KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276
            K K  L+ E  +L++  + + + KG+ E   + +E Q+ EL+ K  E +R+  +L  +  
Sbjct: 1222 KEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRA 1281

Query: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336
            +LQ E    +  L + D+  S+L++   A   Q+++ +  L+EE + K +L+  L+    
Sbjct: 1282 RLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRH 1341

Query: 1337 EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKDLE 1395
            + +  REQ EEE+E K  L++ ++  +++VA  + K E D++   E  EE K+KL + L+
Sbjct: 1342 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1401

Query: 1396 GLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
               +  E   A    LEKTK RLQ E++DL++D++    +   L+KKQ+ FD++L+E K 
Sbjct: 1402 EAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWK- 1460

Query: 1456 ISAKYAEERDRAEAEAREKETKALS-----LARALEEAMEQKAELERLNKQFRTEMEDLM 1510
               KY  E  +AE EA +KE+++LS     +    EE+++Q   L R NK  + E+ DL 
Sbjct: 1461 --QKY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLT 1516

Query: 1511 SSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570
                + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ L  +K++ +
Sbjct: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1576

Query: 1571 RDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630
            R +  +DE+ ++ K+   R V  M++ L+ E + R+ A+  +KK+E DL ++E  ++ AN
Sbjct: 1577 RKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHAN 1636

Query: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 1690
            +   E+++  R  Q  +K+    LDD    +E++  Q    E++   ++AE+ +L   L 
Sbjct: 1637 RLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLE 1696

Query: 1691 AAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 1750
              ER+++ A+QE  + ++ +     +    +  K++LE  ++QL+ E+EE    +    +
Sbjct: 1697 QTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEE 1756

Query: 1751 RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810
            + KKA      +  +L  E+  +   E  ++ LE+  K+L+ +L E E       K  I 
Sbjct: 1757 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1816

Query: 1811 ALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAST 1870
             LEA++ +LE +++NE K    A K +R+ E+++K++  Q +++R+N  + +D  DK   
Sbjct: 1817 KLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQA 1876

Query: 1871 RLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            ++K  KRQ EEAEE++    +  RKLQ ELE+A E AD    +V+ L+ K R
Sbjct: 1877 KVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928



 Score =  240 bits (612), Expect = 1e-62
 Identities = 211/981 (21%), Positives = 459/981 (46%), Gaps = 82/981 (8%)

Query: 832  TKVKPLLQVSRQE--EEMMAKEEEL-------VKVREKQLAAENRLTEMETLQSQLMAEK 882
            +K K  LQ + Q+  +++ A+E+++        K+ ++    E  L + + L+  L   K
Sbjct: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055

Query: 883  LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
             +L+  L+   E   + E  + +L  K ++ E    +L +++E+E+     LQ + K++Q
Sbjct: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115

Query: 943  QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
              I+EL E++E E ++R K + ++     +L+++ E    LE+     + + +L + R A
Sbjct: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQVELNKKREA 1172

Query: 1003 EFTTNLTEEEEKSKS----LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
            EF     + EE +      +A L+ KH   + +L E++   ++ +Q+LEK + +L+ ++ 
Sbjct: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232

Query: 1059 DLSDQIA--------------ELQAQIAELKMQLAKKEE---ELQAALARVEEEAAQKNM 1101
            DLS                   L+ Q++ELK +  +++    +L A  AR++ EA + + 
Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292

Query: 1102 ALKKIRELESQIS-----------ELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
             L +   L SQ+S           EL+  LE E  ++N      +    + + L+ + E+
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352

Query: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210
              +  A  Q   SK   EV   +   E +A     +++E ++K +Q ++E  E +E    
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412

Query: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
              A+LEK KQ L+NE  +L  +V+         + K++  +  L E + K+ E +     
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472

Query: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
               +   L  EL  V  +  +S  +   L ++   L+ ++ D  E + E  +Q   L   
Sbjct: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532

Query: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL-ETAEEVKRK 1389
             KQVE EK   +  LEE E +  + E +I  +  ++  +K +++  +    E  +++KR 
Sbjct: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRN 1592

Query: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449
              + +E +    + ++ + +   + K +++ +L+++ + L+H  + A    +  +    +
Sbjct: 1593 HTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGI 1652

Query: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDL 1509
            L                     +E +       R  E+  EQ A +ER     + E+E+L
Sbjct: 1653 L---------------------KETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEEL 1691

Query: 1510 MSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQF 1569
             ++       + + E+S++  EQ++ +   +++ L  +  +  + K +LE ++  ++++ 
Sbjct: 1692 WAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEV 1744

Query: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSA 1629
            E  +Q     +EEK K+ +     M  EL+ E+   +     +K LE  +KDL+  +D A
Sbjct: 1745 EEVIQ-ESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1803

Query: 1630 NKNRDEA-IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
             +   +   KQ++KL+A++++   E+++ +    E +   +++E+++K +     Q +E+
Sbjct: 1804 EQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELT---YQTEED 1860

Query: 1689 LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI 1748
                 R     Q   D+L  ++ +   +   A E+     ++  +L+ ELEE +   ++ 
Sbjct: 1861 RKNVLRL----QDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIA 1916

Query: 1749 NDRLKKANLQIDQINTDLNLE 1769
              ++ K  ++  +++T ++ E
Sbjct: 1917 ESQVNKLRVKSREVHTKISAE 1937



 Score =  236 bits (602), Expect = 2e-61
 Identities = 212/956 (22%), Positives = 440/956 (46%), Gaps = 105/956 (10%)

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI--- 1064
            L +  E  K +A +K + +      ++ L + E +R+ELE+    L  +  DL  Q+   
Sbjct: 842  LLKSAETEKEMATMKEEFQKT----KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSE 897

Query: 1065 AELQAQIAELKMQLAKKEEELQAALARV-----EEEAAQKNMALKKIRELESQISELQED 1119
            A+  A   E   QL K + +L+A +  V     EEE     +  KK R+LE + SEL++D
Sbjct: 898  ADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKK-RKLEDECSELKKD 956

Query: 1120 LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
            ++    +  K EK+K        A + ++++  +  A   E  +K  +E    KK L+E 
Sbjct: 957  IDDLELTLAKVEKEKH-------ATENKVKNLTEEMAGLDETIAKLSKE----KKALQE- 1004

Query: 1180 AKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQG 1239
              TH+  + ++     QA E+    L + K       K +Q +++  G L  E K+ +  
Sbjct: 1005 --THQQTLDDL-----QAEEDKVNILTKAKT------KLEQQVDDLEGSLEQEKKLRM-- 1049

Query: 1240 KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKL 1299
              D E  ++K+E  L+  Q    + E  + +L +K+ K + E+ N               
Sbjct: 1050 --DLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISN--------------- 1092

Query: 1300 TKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQI 1359
                  L S+++D Q +       ++ L  K+K+++       E++E E  ++   EKQ 
Sbjct: 1093 ------LISKIEDEQAV-------EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQR 1139

Query: 1360 ATLHAQVADMKKKMEDSVGCLETAEEVKRK-------LQKDLEGLSQRHEEKVAAY---- 1408
            + L  ++ ++ +++E++ G      E+ +K       L++DLE  + +HE  VAA     
Sbjct: 1140 SDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKH 1199

Query: 1409 ------------------DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLL 1450
                               KLEK K+ L+ E DDL  + +   ++  NLEK  +  +  +
Sbjct: 1200 ADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQV 1259

Query: 1451 AEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLM 1510
            +E KT   +     +   A+    +T+A   +R L+E     ++L R  +    ++E+L 
Sbjct: 1260 SELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELK 1319

Query: 1511 SSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570
               ++  K+ + L  + ++     + ++ Q EE ++     + A  +    +   + ++E
Sbjct: 1320 HQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYE 1379

Query: 1571 RDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630
             D   R E+ EE KK+L ++++E E  +E    + +     +++L+ +++DL   ++ +N
Sbjct: 1380 TDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSN 1439

Query: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 1690
                   K+ R     + +  ++ ++T+A  E    +++    +L  ++    +  ++L 
Sbjct: 1440 AACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLE 1499

Query: 1691 AAERAKRQAQQERDELADEIANSSGKGALALEE-KRRLEARIAQLEEELEEEQGNTELIN 1749
               R  +  QQE  +L ++IA   GK    LE+ K+++E    +++  LEE + + E   
Sbjct: 1500 TLRRENKNLQQEISDLTEQIAEG-GKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEE 1558

Query: 1750 DRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASI 1809
             ++ +  L+++Q+ +++  +R  A+K+E   Q      + ++     ++  ++S+  A  
Sbjct: 1559 GKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALR 1616

Query: 1810 TA--LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADK 1867
                +E  + ++E QL++  +    + +  R T+  LK+  L +DD  R  E  K+Q   
Sbjct: 1617 VKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI 1676

Query: 1868 ASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
               R   L+ ++EE     ++   SR+  ++EL DA+E    ++ + +SL N  ++
Sbjct: 1677 VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1732



 Score =  152 bits (384), Expect = 3e-36
 Identities = 146/646 (22%), Positives = 295/646 (45%), Gaps = 51/646 (7%)

Query: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
            KS++  K+ + ++ + Q T++ L +   ++  L  K+  +  EKN  + Q++ E ++  +
Sbjct: 844  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903

Query: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
             E++   L      ++ K+++     E  EE+  +L               A   KLE  
Sbjct: 904  AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAEL--------------TAKKRKLEDE 949

Query: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
             + L++++DDL + L    +     E K K   + +A      AK ++E+ +A  E  ++
Sbjct: 950  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEK-KALQETHQQ 1008

Query: 1475 ETKALSLARALEEAMEQKAE-LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
                L       +A E K   L +   +   +++DL  S +   K   +LE++KR LE  
Sbjct: 1009 TLDDL-------QAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD 1061

Query: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
            ++  +    ++E++ Q  ++   + E  +  + ++ E D Q  + Q ++K K+L  ++ E
Sbjct: 1062 LKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIE-DEQAVEIQLQKKIKELQARIEE 1120

Query: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
            +  E+E ER  R+ A   R  L  +L+++   ++ A       ++  +K +A+ +   R+
Sbjct: 1121 LGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRD 1180

Query: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
            L++     E ++A  +      K     M +L E++   +R K++ ++E+ EL  E  + 
Sbjct: 1181 LEEATLQHEAMVAALR------KKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDL 1234

Query: 1714 SGKGALALEEKRRLEARIAQLEEELEE----EQGNTELIND-RLKKANLQIDQINTDLNL 1768
            S       + K  LE     LE+++ E    E+    LIND   ++A LQ +       L
Sbjct: 1235 SSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQL 1294

Query: 1769 ERSHAQKNENAR--QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNE 1826
            +   A  ++ +R  Q   +Q +ELK +L+E E   K+    ++ +       L EQ +  
Sbjct: 1295 DEKDALVSQLSRSKQASTQQIEELKHQLEE-ETKAKNALAHALQSSRHDCDLLREQYE-- 1351

Query: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
             +E++   +  R   K   +V         +A Q  ++ ++A    K+L ++L+EAEE  
Sbjct: 1352 -EEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQEAEEHV 1407

Query: 1887 QRANA-------SRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
            +  NA       ++++LQ E+ED     +  N   ++L  K R  D
Sbjct: 1408 EAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFD 1453



 Score =  122 bits (305), Expect = 4e-27
 Identities = 124/584 (21%), Positives = 253/584 (43%), Gaps = 61/584 (10%)

Query: 828  WRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQE 887
            WR   +   + +    EE      + L +  E   A   +   +E  + +L  E   L  
Sbjct: 1374 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLML 1433

Query: 888  QLQAETELCAEAEELRAR----LTAKKQELEEICHDLEAR-----------------VEE 926
             ++     CA  ++ +      L+  KQ+ EE   +LEA                   EE
Sbjct: 1434 DVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493

Query: 927  EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKK------LEEEQ 980
              ++ + L+ E K +QQ I +L EQ+ E    +Q  +LEK+  + + +K      LEE +
Sbjct: 1494 SLDQLETLRRENKNLQQEISDLTEQIAE--GGKQIHELEKIKKQVEQEKCEIQAALEEAE 1551

Query: 981  IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE 1040
              LE +  K+ + +  L    +E    + E++E+   + +LK  H  ++  ++  L  E 
Sbjct: 1552 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE---IDQLKRNHTRVVETMQSTLDAEI 1608

Query: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ-------LAKKEEELQAALARVE 1093
            + R +  + ++K+EGD  ++  Q+       AE           L + +  L  AL   E
Sbjct: 1609 RSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQE 1668

Query: 1094 EEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLD 1153
            +   Q  +  ++   L+++I EL   LE    SR  AE++  D  E ++ L T+    ++
Sbjct: 1669 DLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1728

Query: 1154 STAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKA 1213
            +       + K E +V+ L+  +EE  +      +E  +K       +AE+L++ +   A
Sbjct: 1729 T-------KKKLENDVSQLQSEVEEVIQ-ESRNAEEKAKKAITDAAMMAEELKKEQDTSA 1780

Query: 1214 NLEKAKQTLENERGELANEV----KVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRT 1269
            +LE+ K+ LE    +L + +    ++ L+G    + + +K+EA+++EL+ +    ++   
Sbjct: 1781 HLERMKKNLEQTVKDLQHRLDEAEQLALKG---GKKQIQKLEARVRELEGEVENEQKRNA 1837

Query: 1270 ELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLST 1329
            E    + K +  +  +T    +      +L      L+++++  +   +E   Q  +  +
Sbjct: 1838 EAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLS 1897

Query: 1330 KLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373
            K ++++ E       LEE EE     E Q+  L  +  ++  K+
Sbjct: 1898 KFRKLQHE-------LEEAEERADIAESQVNKLRVKSREVHTKI 1934


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 1406 bits (3640), Expect = 0.0
 Identities = 771/1903 (40%), Positives = 1163/1903 (61%), Gaps = 26/1903 (1%)

Query: 33   WVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCL 92
            +VP DK  F  A +    G + I E  ENGK V V +D + + NPPKF K+EDMA LT L
Sbjct: 38   FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96

Query: 93   NEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYA 152
            +E +VL NLKERY + +IYTYSGLFCV +NPYK LP+Y+ E+V  Y+GKKR E PPHI++
Sbjct: 97   HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156

Query: 153  ITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS-SHKSKKD-----QGE 206
            I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A+   + KKD     +G 
Sbjct: 157  ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGT 216

Query: 207  LERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIR 266
            LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLEKSR I 
Sbjct: 217  LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIF 276

Query: 267  QAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDMFQETME 324
            Q K ER +HIFY +LS     L   LL+   PY+ Y F+S G V++    D +    T  
Sbjct: 277  QLKAERNYHIFYQILSNKKPELLDMLLVTNNPYD-YAFVSQGEVSVASIDDSEELMATDS 335

Query: 325  AMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTD 384
            A  ++G   EE+ G+ ++   ++  GN+ FK+++  +QA       A K ++L+G+N  D
Sbjct: 336  AFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSAD 395

Query: 385  FTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQG 444
              +G+  PR+KVG +YV K Q+ +Q  ++I ALAKA YE+MF W+V RIN  L+ TK+  
Sbjct: 396  LLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE-TKQPR 454

Query: 445  ASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 504
              FIG+LDIAGFEIFD NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW FIDF
Sbjct: 455  QYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDF 514

Query: 505  GLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTHPKFQKPKQLK 563
            G+DLQ CIDLIEKP G   I+++L+EEC FPKATD +F  K+     G    FQKP+ +K
Sbjct: 515  GMDLQACIDLIEKPMG---IMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK 571

Query: 564  DK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGL 621
             K  A F +IHYAG VDY    WL KN DPLN+ +  L  +SS K ++ L+         
Sbjct: 572  GKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY------ 625

Query: 622  DQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAG 681
               A   ++      K +   F+TV  L++E L KLM  LR T+P+FVRCIIPN  K  G
Sbjct: 626  -ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPG 684

Query: 682  KLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDGKQAC 740
             +D  LV+ QLRCNGVLEGIRICR+GFPNR+++ +FRQRY IL P +IP+G F+D ++  
Sbjct: 685  VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGT 744

Query: 741  VLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFA 800
              ++ +L++D N Y+ G +KVFF+AG+L  LEE RD +++ +I   QA  RG L R  F 
Sbjct: 745  EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFK 804

Query: 801  KRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREK 860
            K  ++  A+ V+Q N  A++ ++NW W +L+ K+KPLL+ +  E+EM   +EE  +++E 
Sbjct: 805  KIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKET 864

Query: 861  QLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDL 920
               +E R  E+E     L+ EK  LQ Q+QAE +   +AEE   +L   K +LE    ++
Sbjct: 865  LEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEM 924

Query: 921  EARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQ 980
              R+E+EEE    L A+K+K++    EL++ +++ E    K++ EK  TE K+K L EE 
Sbjct: 925  NERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984

Query: 981  IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE 1040
              L++   KL KEKK L++   +   +L  EE+K  SL+K K K E  + DLE  L +E+
Sbjct: 985  AGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEK 1044

Query: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKN 1100
            K R +LE+ +RKLEGD     + I +L+    +L+ +L KKE ++    +++E+E     
Sbjct: 1045 KVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLAL 1104

Query: 1101 MALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQE 1160
               KK++E +++I EL+E+LE+ER +R K EK + DL  ELE +   LE+   +T+ Q E
Sbjct: 1105 QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164

Query: 1161 LRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQ 1220
            +  KRE E   +++ LEE    HEA    +R+KH+ +V EL EQ++  +RVK  LEK K 
Sbjct: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224

Query: 1221 TLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQV 1280
              + E  ++ + ++ +++ K + E   + +E Q  E +VK  E +R   +   +  KLQ 
Sbjct: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284

Query: 1281 ELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
            E   +   L + ++  S+LT+   +   Q++D +  L+EE + K +L+  L+    + + 
Sbjct: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344

Query: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKDLEGLSQ 1399
             REQ EEE EAK  L++ ++  +++VA  + K E D++   E  EE K+KL + L+   +
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404

Query: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAK 1459
              E   A    LEKTK RLQ E++DL+VD++    +A  L+KKQ+ FD++LAE K    +
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464

Query: 1460 YAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519
               E + ++ EAR   T+   L  A EE++E     +R NK  + E+ DL     + GK+
Sbjct: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKN 1524

Query: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
            VHELEK ++ LE +  E+++ LEE E  L+  E   LR ++    +KA+ ER L  +DE+
Sbjct: 1525 VHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1584

Query: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639
             E+ K+   R V  ++  L+ E + R+  +  +KK+E DL ++E  +  AN+   EA KQ
Sbjct: 1585 MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1644

Query: 1640 LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1699
            ++ LQ+ +KD   +LDD   + +++       E++   ++AE+ +L+  +   ER+++ A
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704

Query: 1700 QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759
            +QE  E ++ +     +    + +K+++E+ + QL+ E+EE         ++ KKA    
Sbjct: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDA 1764

Query: 1760 DQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819
              +  +L  E+  +   E  ++ +E+  K+L+ +L E E       K  +  LEA++ +L
Sbjct: 1765 AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVREL 1824

Query: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQL 1879
            E +L+ E K    + K +R++E+++K++  Q +++++N  + +D  DK   ++K  KRQ 
Sbjct: 1825 EGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQA 1884

Query: 1880 EEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            EEAEE+A    +  RK+Q EL++A E AD    +V+ L+ K R
Sbjct: 1885 EEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927



 Score =  239 bits (611), Expect = 1e-62
 Identities = 196/898 (21%), Positives = 413/898 (45%), Gaps = 50/898 (5%)

Query: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
            AE + ++A +K +  + +E L+ + AR +E   +    L++  +L+ Q+   Q++L    
Sbjct: 845  AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904

Query: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
               ++  K K  L  +++ +   LED  +  A     + K E E + LKK +++   T  
Sbjct: 905  ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTL- 963

Query: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
            A++++ +      V+ L E++     + A L K K+ L+    +  ++++V         
Sbjct: 964  AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLS 1023

Query: 1245 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 1304
              + K+E Q+ +L+    + ++VR +L     KL+ +L      +   ++   +L +   
Sbjct: 1024 KSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLK 1083

Query: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA 1364
              E  +      +++E    L L  KLK+ +       E+LE E  A+  +EK  + L  
Sbjct: 1084 KKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSR 1143

Query: 1365 QVADMKKKMEDSVGCLETAEEVKRK-------LQKDLEGLSQRHEEKVAAY--------- 1408
            ++ ++ +++E++ G      E+ +K       +++DLE  + +HE   AA          
Sbjct: 1144 ELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVA 1203

Query: 1409 -------------DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
                          KLEK K+  + ELDD+  +++   ++  NLEK  +  +    E + 
Sbjct: 1204 ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRV 1263

Query: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDD 1515
               +     +    +  + +T+   LAR LEE     ++L R    +  +MEDL    ++
Sbjct: 1264 KLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE 1323

Query: 1516 VGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
             GK+ + L  + ++     + ++ Q EE  +     +    +    +   + ++E D   
Sbjct: 1324 EGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQ 1383

Query: 1576 RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDE 1635
            R E+ EE KK+L +++++ E  +E    + S     + +L+ +++DL   ++ +N     
Sbjct: 1384 RTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1443

Query: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQL----QEELAA 1691
              K+ R          + L + +   EE  ++ + ++K+ +S+  E+ +L    +E L  
Sbjct: 1444 LDKKQRNFD-------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEH 1496

Query: 1692 AERAKRQAQQERDELAD--EIANSSGKGALALEEKRR-LEARIAQLEEELEEEQGNTELI 1748
             E  KR+ +  ++E++D  E     GK    LE+ R+ LE    +L+  LEE + + E  
Sbjct: 1497 LETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHE 1556

Query: 1749 NDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQ---EMEGTVKSKY 1805
              ++ +A L+ +QI  ++  ER  A+K+E   +Q +R ++ +   LQ   + E   +++ 
Sbjct: 1557 EGKILRAQLEFNQIKAEI--ERKLAEKDEEM-EQAKRNHQRVVDSLQTSLDAETRSRNEV 1613

Query: 1806 KASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQA 1865
                  +E  + ++E QL +  +    A KQV+  +  LKD  +Q+DD  R  +  K+  
Sbjct: 1614 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENI 1673

Query: 1866 DKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
                 R   L+ +LEE     ++   SR+  ++EL + +E    ++ + +SL N+ ++
Sbjct: 1674 AIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1731



 Score =  201 bits (512), Expect = 4e-51
 Identities = 191/948 (20%), Positives = 411/948 (43%), Gaps = 101/948 (10%)

Query: 832  TKVKPLLQVSRQE--EEMMAKEEELVKVREKQLAAENRLTEME-------TLQSQLMAEK 882
            TK K  LQ + Q+  +++  +E+++  + + ++  E ++ ++E        ++  L   K
Sbjct: 995  TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1054

Query: 883  LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
             +L+  L+   E   + E  + +L  K ++ E   +   +++E+E+     LQ + K+ Q
Sbjct: 1055 RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQ 1114

Query: 943  QNIQELEEQLEEEESARQKLQ---------LEKVTT-------------------EAKLK 974
              I+ELEE+LE E +AR K++         LE+++                    EA+ +
Sbjct: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1174

Query: 975  KLEE--EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDL 1032
            K+    E+  L+ +    A  KK   D +AE    +   +   + L K K++ +  + D+
Sbjct: 1175 KMRRDLEEATLQHEATAAALRKKHA-DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1233

Query: 1033 EERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARV 1092
               + +  K +  LEK  R LE  + +   ++ E Q  + +   Q AK + E      ++
Sbjct: 1234 TSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQL 1293

Query: 1093 EEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTL 1152
            EE+ A  +   +       Q+ +L+  LE E  ++N      +    + + L+ + E+  
Sbjct: 1294 EEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEET 1353

Query: 1153 DSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVK 1212
            ++ A  Q + SK   EV   +   E +A     +++E ++K +Q +++  E +E      
Sbjct: 1354 EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKC 1413

Query: 1213 ANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELA 1272
            ++LEK K  L+NE  +L  +V+         + K++  +  L E + K+ E +       
Sbjct: 1414 SSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQ 1473

Query: 1273 DKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLK 1332
             +   L  EL  +     +S        ++   L+ ++ D  E L E  +    L    K
Sbjct: 1474 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRK 1533

Query: 1333 QVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL-ETAEEVKRKLQ 1391
            Q+E EK   +  LEE E +  + E +I     +   +K ++E  +    E  E+ KR  Q
Sbjct: 1534 QLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQ 1593

Query: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA 1451
            + ++ L    + +  + +++ + K +++ +L+++ + L H  + A   +K+ K    LL 
Sbjct: 1594 RVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1653

Query: 1452 EEKT-------------------------ISAKYAE--------ERDR--AEAEAREKET 1476
            + +                          + A+  E        ER R  AE E  E   
Sbjct: 1654 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1713

Query: 1477 KALSLARALEEAMEQKAELERLNKQFRTEMEDLMSS----------------------KD 1514
            +   L       + QK ++E    Q ++E+E+ +                        K 
Sbjct: 1714 RVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1773

Query: 1515 DVGKSVHELEKSKRALEQQVEEMKTQLEELED-ELQATEDAKLRLEVNLQAMKAQFERDL 1573
            +   S H LE+ K+ +EQ +++++ +L+E E   L+  +    +LE  ++ ++ + E + 
Sbjct: 1774 EQDTSAH-LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAE- 1831

Query: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633
            Q R+ +S +  ++  R+++E+  + E+++K          KL++ +K  +   + A +  
Sbjct: 1832 QKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQA 1891

Query: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAE 1681
            +  + + RK+Q ++ +     D   +   ++ A++++   K K  + E
Sbjct: 1892 NTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939



 Score =  151 bits (381), Expect = 7e-36
 Identities = 150/650 (23%), Positives = 298/650 (45%), Gaps = 59/650 (9%)

Query: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
            KS++  K+ + ++ +    +E L++   ++  L  K+  +  EKN  + Q++ E++  ++
Sbjct: 843  KSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLND 902

Query: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
             E++   L      ++ K+++    LE  EE+  +L               A   KLE  
Sbjct: 903  AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAEL--------------TAKKRKLEDE 948

Query: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
             + L++++DDL + L    +     E K K   + +A    I AK  +E+ +A  EA ++
Sbjct: 949  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEK-KALQEAHQQ 1007

Query: 1475 ETKALSLARALEEAMEQKAELERLNK---QFRTEMEDLMSSKDDVGKSVHELEKSKRALE 1531
                     AL++   ++ ++  L+K   +   +++DL  S +   K   +LE++KR LE
Sbjct: 1008 ---------ALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLE 1058

Query: 1532 QQVEEMKTQLEELE-DELQATEDAKLR-LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 1589
              ++  +  + +LE D+LQ  E  K +  ++N Q  K + E+ L     Q ++K K+   
Sbjct: 1059 GDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLA---LQLQKKLKENQA 1115

Query: 1590 QVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKD 1649
            ++ E+E ELE ER  R+     R  L  +L+++   ++ A       I+  +K +A+ + 
Sbjct: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1175

Query: 1650 CMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADE 1709
              R+L++     E   A  +      K     + +L E++   +R K++ ++E+ E   E
Sbjct: 1176 MRRDLEEATLQHEATAAALR------KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1229

Query: 1710 IANSSGKGALALEEKRRLEARIAQLEEELEE-----EQGNTELINDRLKKANLQIDQINT 1764
            + + +      ++ K  LE     LE++  E     E+    L +   ++A LQ +    
Sbjct: 1230 LDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGEL 1289

Query: 1765 DLNLERSHAQKNENARQQLE--RQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1822
               LE   A  ++  R +L   +Q ++LK +L+E EG  K+    ++ +       L EQ
Sbjct: 1290 ARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE-EGKAKNALAHALQSARHDCDLLREQ 1348

Query: 1823 LDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEA 1882
             + ET   +A  +  R   K   +V         +A Q  ++ ++A    K+L ++L++A
Sbjct: 1349 YEEET---EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQDA 1402

Query: 1883 EEEAQRANA-------SRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
            EE  +  NA       ++ +LQ E+ED     +  N   ++L  K R  D
Sbjct: 1403 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1452


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 1405 bits (3637), Expect = 0.0
 Identities = 770/1909 (40%), Positives = 1178/1909 (61%), Gaps = 27/1909 (1%)

Query: 28   AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
            AK  V+V   K  F  A+++   G +   +  E G  V V  D +  MNPPK+ K+EDMA
Sbjct: 34   AKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKYDKIEDMA 92

Query: 88   ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
             +T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y+ E+V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAP 152

Query: 148  PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203
            PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+    
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTS 212

Query: 204  ---QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLE 260
               QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLE
Sbjct: 213  GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272

Query: 261  KSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDM 318
            KSR   Q K ER++HIFY ++S     L   LL+   PY+ Y F+S G +T+P   D++ 
Sbjct: 273  KSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYD-YAFVSQGEITVPSIDDQEE 331

Query: 319  FQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLL 378
               T  A+ I+G   +E++ + ++   V+  GN+ FK+++  +QA       A K ++L 
Sbjct: 332  LMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQ 391

Query: 379  GINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD 438
             +N  D  + +  PR+KVG +YV K QT +Q   A+ ALAKA Y++MF W+V RIN+ LD
Sbjct: 392  NLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLD 451

Query: 439  KTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 498
             TK+    FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIE
Sbjct: 452  -TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510

Query: 499  WNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTHPKFQ 557
            W FIDFG+DL  CI+LIEKP G   I ++L+EEC FPKATD SF  K+ ++  G    FQ
Sbjct: 511  WTFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567

Query: 558  KPKQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDV 615
            KPK  K K  A F +IHYAG VDY    WL KN DPLN+ +  L  +S+ K ++ L+   
Sbjct: 568  KPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLFVGA 627

Query: 616  DRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675
                G +  AG  +       K +   F+TV  L++E L KLM  LR+T+P+FVRCIIPN
Sbjct: 628  T---GAEAEAGGGKKG----GKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 680

Query: 676  HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FM 734
              K  G ++  LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L  ++IP+G F+
Sbjct: 681  ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 740

Query: 735  DGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYL 794
            D K+A   ++ ++++D   Y+ G +KVFF+AG+L  LEE RD K+  +I   QA CRG+L
Sbjct: 741  DSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFL 800

Query: 795  ARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEEL 854
            AR  + K  ++  ++  +Q N  A++ +++W W +L+ K+KPLL+ +  E+EM   +EE 
Sbjct: 801  ARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEF 860

Query: 855  VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE 914
             K +E+    E +  E+E     LM EK  LQ Q+QAE +  A+AEE   +L   K +LE
Sbjct: 861  EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLE 920

Query: 915  EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974
                ++  R E+EEE    L A+K+K++    EL++ +++ E    K++ EK  TE K+K
Sbjct: 921  AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 980

Query: 975  KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
             L EE   L++   KL KEKK L++   +   +L  EE+K  +L K K K E  + DLE 
Sbjct: 981  NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1040

Query: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1094
             L +E+K R +LE+ +RKLEGD     +   +++    +L  +L KKE E+    +++E+
Sbjct: 1041 SLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100

Query: 1095 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154
            E A      KKI+EL+++I EL+E++E+ERASR KAEKQ+ DL  ELE +   LE+   +
Sbjct: 1101 EQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160

Query: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
            T+AQ E+  KRE E   +++ LEE    HEA    +R+KH+ +V EL EQ++  +RVK  
Sbjct: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220

Query: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
            LEK K  ++ E  +LA+ ++ + + KG+ E   + +E QL E++ K  E +R+  +L  +
Sbjct: 1221 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 1280

Query: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
              +LQ E    +  L + D+  S+L++   A   Q+++ +  L+EE + K +L+  L+  
Sbjct: 1281 RARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 1340

Query: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKD 1393
              + +  REQ EEE+EAK  L++ ++  +++VA  + K E D++   E  EE K+KL + 
Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400

Query: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453
            L+   +  E   A    LEKTK RLQ E++DL++D++    +   L+KKQ+ FD++LAE 
Sbjct: 1401 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEW 1460

Query: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513
            K    +   E + ++ E+R   T+   +  A EE+++Q   L+R NK  + E+ DL    
Sbjct: 1461 KQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1520

Query: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573
             + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ L  +K++ +R +
Sbjct: 1521 AEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1580

Query: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633
              +DE+ ++ K+  +R V  M++ L+ E + R+ A+  +KK+E DL ++E  ++ AN+  
Sbjct: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640

Query: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693
             EA++  R  QA +KD    LDD   S+E++  Q    E++   ++AE+ +L+  L   E
Sbjct: 1641 AEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1700

Query: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK 1753
            R+++ A+QE  + ++ +     +    +  K++LE  I+Q++ E+E+         ++ K
Sbjct: 1701 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAK 1760

Query: 1754 KANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALE 1813
            KA      +  +L  E+  +   E  ++ LE+  K+L+ +L E E       K  I  LE
Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820

Query: 1814 AKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLK 1873
            A++ +LE ++++E K    A K +R+ E+K+K++  Q +++R+N  + +D  DK   ++K
Sbjct: 1821 ARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1880

Query: 1874 QLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
              KRQ EEAEE++    +  R++Q ELE+A E AD    +V+ L+ K R
Sbjct: 1881 SYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929



 Score =  258 bits (658), Expect = 5e-68
 Identities = 228/939 (24%), Positives = 446/939 (47%), Gaps = 71/939 (7%)

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI--- 1064
            L +  E  K +A +K + E      +E L + E +R+ELE+    L  +  DL  Q+   
Sbjct: 843  LLKSAETEKEMANMKEEFEKT----KEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898

Query: 1065 AELQAQIAELKMQLAKKEEELQAALARV-----EEEAAQKNMALKKIRELESQISELQED 1119
            A+  A   E   QL K + +L+A +  V     +EE     +  KK R+LE + SEL++D
Sbjct: 899  ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKD 957

Query: 1120 LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE-- 1177
            ++    +  K EK+K     +++ L  E+   LD T A+     K  QE +  ++TL+  
Sbjct: 958  IDDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKLTKEKKALQEAH--QQTLDDL 1014

Query: 1178 --EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
              EE K +   + + + K  Q V++L   LEQ K+++ +LE+AK+ LE +  +LA E  +
Sbjct: 1015 QAEEDKVNT--LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL-KLAQESTM 1071

Query: 1236 LLQG-KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDS 1294
             ++  K   + K KK E ++  LQ K  + + +  +L  K+ +LQ  ++ +   +    +
Sbjct: 1072 DIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERA 1131

Query: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
              +K  K  S L  +L++  E L+E      +     K+ E E    R  LEE       
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE------- 1184

Query: 1355 LEKQIATLH--AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLE 1412
                 ATL   A  A ++KK  DSV   E  E++      +L+ + Q          KLE
Sbjct: 1185 -----ATLQHEATAATLRKKHADSVA--ELGEQID-----NLQRVKQ----------KLE 1222

Query: 1413 KTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAR 1472
            K K+ ++ E+DDL  +++   ++  NLEK  +  +  L+E KT   +     +   A+  
Sbjct: 1223 KEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRA 1282

Query: 1473 EKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532
              +T++   +R L+E     ++L R  + F  ++E+L    ++  K+   L  + ++   
Sbjct: 1283 RLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRH 1342

Query: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1592
              + ++ Q EE ++     + A  +    +   + ++E D   R E+ EE KK+L ++++
Sbjct: 1343 DCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1402

Query: 1593 EMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR 1652
            + E  +E    + +     +++L+ +++DL   ++  N       K+ R     + +  +
Sbjct: 1403 DAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462

Query: 1653 ELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIAN 1712
            + ++T A  E    +++    +L  ++    +  ++L   +R  +  QQE  +L ++IA 
Sbjct: 1463 KCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1522

Query: 1713 SSGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERS 1771
              GK    LE+ K+++E   ++L+  LEE + + E    ++ +  L+++Q+ +++  +R 
Sbjct: 1523 G-GKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRK 1579

Query: 1772 HAQKNENARQQ-------LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
             A+K+E   Q        +E     L  +++     ++ K K     +E  + ++E QL+
Sbjct: 1580 IAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK-----MEGDLNEMEIQLN 1634

Query: 1825 NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884
            +  +    A +  R T+  LKD  L +DD  R+ E  K+Q      R   L+ ++EE   
Sbjct: 1635 HANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRA 1694

Query: 1885 EAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
              ++   SR+  ++EL DA+E    ++ + +SL N  ++
Sbjct: 1695 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1733



 Score =  191 bits (486), Expect = 5e-48
 Identities = 212/949 (22%), Positives = 427/949 (44%), Gaps = 160/949 (16%)

Query: 832  TKVKPLLQVSRQE--EEMMAKEEELVKVREKQLAAENRLTEME-------TLQSQLMAEK 882
            TK K  LQ + Q+  +++ A+E+++  + + ++  E ++ ++E        ++  L   K
Sbjct: 997  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1056

Query: 883  LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
             +L+  L+   E   + E  + +L  K ++ E     L++++E+E+     LQ + K++Q
Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116

Query: 943  QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
              I+ELEE++E E ++R K + ++     +L+++ E    LE+     + + ++ + R A
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQIEMNKKREA 1173

Query: 1003 EFTTNLTEEEEKS----KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
            EF     + EE +     + A L+ KH   + +L E++   ++ +Q+LEK + +++ +  
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233

Query: 1059 DLSDQIAE--------------LQAQIAELKMQLAKKEE---ELQAALARVEEEAAQKNM 1101
            DL+  +                L+ Q++E+K +  +++    +L A  AR++ E+ + + 
Sbjct: 1234 DLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSR 1293

Query: 1102 ALKKIRELESQIS-----------ELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
             L +   L SQ+S           EL+  LE E  +++      +    + + L+ + E+
Sbjct: 1294 QLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE 1353

Query: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210
              ++ A  Q   SK   EV   +   E +A     +++E ++K +Q +++  E +E    
Sbjct: 1354 EQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNA 1413

Query: 1211 VKANLEKAKQTLENERGELANEV------------------KVLLQGKGDSEHKRKKVEA 1252
              A+LEK KQ L+NE  +L  +V                  K+L + K   E    ++EA
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1473

Query: 1253 QLQELQVKFNEGERVRTELADKVTKL----------QVELDNVTGLLSQSDSKSSKLTK- 1301
              +E +    E  +++    + + +L          Q E+ ++T  +++   +  +L K 
Sbjct: 1474 SQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1533

Query: 1302 ------DFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN-SFREQLEEEEEAKHN 1354
                  + S L++ L++ +  L+ E  + L +  +L QV+ E +    E+ EE ++ K N
Sbjct: 1534 KKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRN 1593

Query: 1355 ----LEKQIATLHAQVAD------MKKKMEDSVG-------------------------- 1378
                +E   +TL A++        +KKKME  +                           
Sbjct: 1594 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAI 1653

Query: 1379 ----------CLETAEEVKRKL---QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL 1425
                       L + E++K +L   ++    L    EE  A  ++ E+++   +QEL D 
Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713

Query: 1426 L--VDLDH-QRQSACNLEKK-QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSL 1481
               V L H Q  S  N +KK +    Q+  E + I     +E   AE +A++  T A  +
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDI----IQEARNAEEKAKKAITDAAMM 1769

Query: 1482 ARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG--------KSVHELEKSKRALEQQ 1533
            A  L++  +  A LER+ K     ++DL    D+          K + +LE   R LE +
Sbjct: 1770 AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGE 1829

Query: 1534 VE-EMKTQLEEL-----------EDELQATEDAK--LRLEVNLQAMKAQFERDLQGRDEQ 1579
            VE E K  +E +           E   Q  ED K  LRL+  +  ++A+  +  + + E+
Sbjct: 1830 VESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKV-KSYKRQAEE 1888

Query: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
            +EE+    + + R ++ ELE+  ++  +A +   KL +  +++   I S
Sbjct: 1889 AEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIIS 1937



 Score =  155 bits (391), Expect = 5e-37
 Identities = 147/646 (22%), Positives = 297/646 (45%), Gaps = 51/646 (7%)

Query: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
            KS++  K+ + ++ + + T+E L +   ++  L  K+  +  EKN  + Q++ E ++  +
Sbjct: 845  KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904

Query: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
             E++   L      ++ K+++     E  EE+  +L               A   KLE  
Sbjct: 905  AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAEL--------------TAKKRKLEDE 950

Query: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
             + L++++DDL + L    +     E K K   + +A      AK  +E+ +A  EA ++
Sbjct: 951  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK-KALQEAHQQ 1009

Query: 1475 ETKALSLARALEEAMEQKAE-LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
                L       +A E K   L +   +   +++DL  S +   K   +LE++KR LE  
Sbjct: 1010 TLDDL-------QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD 1062

Query: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
            ++  +    ++E++ Q  ++   + E  +  ++++ E D Q    Q ++K K+L  ++ E
Sbjct: 1063 LKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIE-DEQALGMQLQKKIKELQARIEE 1121

Query: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
            +E E+E ER  R+ A   R  L  +L+++   ++ A       I+  +K +A+ +   R+
Sbjct: 1122 LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD 1181

Query: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
            L++     E   A  +      K     + +L E++   +R K++ ++E+ E+  EI + 
Sbjct: 1182 LEEATLQHEATAATLR------KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235

Query: 1714 SGKGALALEEKRRLEARIAQLEEELEE----EQGNTELIND-RLKKANLQID--QINTDL 1766
            +       + K  LE     LE++L E    E+    LIND   ++A LQ +  + +  L
Sbjct: 1236 ASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL 1295

Query: 1767 NLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNE 1826
            + + +   +    +Q   +Q +ELK +L+E E   KS    ++ +       L EQ +  
Sbjct: 1296 DEKDTLVSQLSRGKQAFTQQIEELKRQLEE-EIKAKSALAHALQSSRHDCDLLREQYE-- 1352

Query: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
             +E++A  +  R   K   +V         +A Q  ++ ++A    K+L ++L++AEE  
Sbjct: 1353 -EEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQDAEEHV 1408

Query: 1887 QRANA-------SRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
            +  NA       ++++LQ E+ED     +  N   ++L  K R  D
Sbjct: 1409 EAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFD 1454



 Score =  118 bits (296), Expect = 5e-26
 Identities = 125/587 (21%), Positives = 256/587 (43%), Gaps = 67/587 (11%)

Query: 828  WRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQE 887
            WR   +   + +    EE      + L    E   A   +   +E  + +L  E   L  
Sbjct: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMI 1434

Query: 888  QLQAETELCA------------------EAEELRARLTAKKQELEEICHDL---EARVEE 926
             ++     CA                  + EE  A L A ++E   +  +L   +   EE
Sbjct: 1435 DVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEE 1494

Query: 927  EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKK------LEEEQ 980
              ++ + L+ E K +QQ I +L EQ+ E    ++  +LEK+  + + +K      LEE +
Sbjct: 1495 SLDQLETLKRENKNLQQEISDLTEQIAE--GGKRIHELEKIKKQVEQEKSELQAALEEAE 1552

Query: 981  IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE 1040
              LE +  K+ + +  L    +E    + E++E+   + ++K  H  ++  ++  L  E 
Sbjct: 1553 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE---IDQMKRNHIRIVESMQSTLDAEI 1609

Query: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAEL-----KMQLAKKEEELQA--ALARVE 1093
            + R +  + ++K+EGD  ++  Q+       AE        Q   K+ +L    AL   E
Sbjct: 1610 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQE 1669

Query: 1094 EEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLD 1153
            +   Q  M  ++   L+++I EL+  LE    SR  AE++  D  E ++ L T+    ++
Sbjct: 1670 DLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1729

Query: 1154 STAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE---LAEQLEQTKR 1210
            +         K++ E +I +   E E    EA+  E  +K  +A+ +   +AE+L++ + 
Sbjct: 1730 T---------KKKLETDISQIQGEMEDIIQEARNAE--EKAKKAITDAAMMAEELKKEQD 1778

Query: 1211 VKANLEKAKQTLENERGELANEV----KVLLQGKGDSEHKRKKVEAQLQELQVKFNEGER 1266
              A+LE+ K+ LE    +L + +    ++ L+G    + + +K+EA+++EL+ +    ++
Sbjct: 1779 TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKG---GKKQIQKLEARVRELEGEVESEQK 1835

Query: 1267 VRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLS 1326
               E    + K + ++  +T    +      +L      L+++++  +   +E   Q   
Sbjct: 1836 RNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNV 1895

Query: 1327 LSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373
              +K ++++ E       LEE EE     E Q+  L  +  ++  K+
Sbjct: 1896 NLSKFRRIQHE-------LEEAEERADIAESQVNKLRVKSREVHTKI 1935


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 1402 bits (3630), Expect = 0.0
 Identities = 773/1914 (40%), Positives = 1175/1914 (61%), Gaps = 37/1914 (1%)

Query: 28   AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
            AK  V+V   K  +  A ++   G +   +  E G  V V +D +  MNPPK+ K+EDMA
Sbjct: 34   AKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKYDKIEDMA 92

Query: 88   ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
             +T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y+ E+V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAP 152

Query: 148  PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203
            PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+    
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPAS 212

Query: 204  ---QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLE 260
               QG LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLE
Sbjct: 213  GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 272

Query: 261  KSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDM 318
            KSR   Q K ER++HIFY +LS     L   LL+   PY+ + F+S G +T+P   D++ 
Sbjct: 273  KSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYD-FAFVSQGEITVPSIDDQEE 331

Query: 319  FQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLL 378
               T  A+ I+G   +E++ + ++   V+  GN+ FK+++  +QA       A K ++L 
Sbjct: 332  LMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLT 391

Query: 379  GINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD 438
             +N  D  + +  PR+KVG ++V K QT +Q   A+ ALAKA YE+MF W+V RIN+ LD
Sbjct: 392  SLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLD 451

Query: 439  KTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 498
             TK+    FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIE
Sbjct: 452  -TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510

Query: 499  WNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTHPKFQ 557
            W FIDFG+DL  CI+LIEKP G   I ++L+EEC FPKATD SF  K+ ++  G    FQ
Sbjct: 511  WEFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQ 567

Query: 558  KPKQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDV 615
            KPK  K K  A F ++HYAG VDY    WL KN DPLN+ +  L  +S+ K ++ L+   
Sbjct: 568  KPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGA 627

Query: 616  DRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675
                   Q A           K +   F+TV  L++E L KLM  LR+T+P+FVRCIIPN
Sbjct: 628  -------QTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 680

Query: 676  HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FM 734
              K  G ++  LVL QLRCNGVLEGIRICR+GFP+R+++ +F+QRY++L  ++IP+G F+
Sbjct: 681  ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 740

Query: 735  DGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYL 794
            D K+A   ++ ++E+D   Y+ G +KVFF+AG+L  LEE RD K+  +I   QA CRG+L
Sbjct: 741  DSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFL 800

Query: 795  ARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEEL 854
             R  F K  ++  ++  +Q N  A++ +++W W +L+ K+KPLL+ +  E+EM   +EE 
Sbjct: 801  MRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEF 860

Query: 855  VKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE 914
             K +E+    E +  E+E     LM EK  LQ Q+QAE +  A+AEE   +L   K +LE
Sbjct: 861  EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLE 920

Query: 915  EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974
                ++  R E+EEE    L A+K+K++    EL++ +++ E    K++ EK  TE K+K
Sbjct: 921  AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 980

Query: 975  KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
             L EE   L++   KL KEKK L++   +   +L  EE+K  +L K K K E  + DLE 
Sbjct: 981  NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEG 1040

Query: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEE 1094
             L +E+K   +LE+ +RKLEGD     +   + +    +L  +L KKE E+     ++E+
Sbjct: 1041 SLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIED 1100

Query: 1095 EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154
            E A      KKI+EL+++I EL+E++E+ERASR KAEKQ+ DL  ELE +   LE+   +
Sbjct: 1101 EQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160

Query: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
            T+AQ E+  KRE E   +++ LEE    HEA    +R+KH+ +V EL EQ++  +RVK  
Sbjct: 1161 TSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQK 1220

Query: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
            LEK K  L+ E  +LA+ ++ + + K + E   + +E QL E++ K  E +R+  EL+ +
Sbjct: 1221 LEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQ 1280

Query: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
              +L  E    +  L + D+  S+L++   A   Q+++ +  L+EE + K +L+  L+  
Sbjct: 1281 KARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSA 1340

Query: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKD 1393
              + +  REQ EEE+EAK  L++ ++  +++VA  + K E D++   E  EE K+KL + 
Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400

Query: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453
            L+   +  E   +    LEKTK RLQ E++DL++D++    +   L+KKQ+ FD++LAE 
Sbjct: 1401 LQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEW 1460

Query: 1454 KTISAKYAEERDRAEAEAREKETKALS-----LARALEEAMEQKAELERLNKQFRTEMED 1508
            K    KY  E  +AE EA +KE+++LS     +  A EE+++    L+R NK  + E+ D
Sbjct: 1461 K---QKY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISD 1515

Query: 1509 LMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQ 1568
            L     + GK +HELEK K+ L+ +  E++T LEE E  L+  E   LR+++ L  +K++
Sbjct: 1516 LTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSE 1575

Query: 1569 FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
             +R +  +DE+ ++ K+  +R V  M++ L+ E + R+ A+  +KK+E DL ++E  ++ 
Sbjct: 1576 IDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNH 1635

Query: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
            AN+   EA++ LR  Q  +KD    LDD    ++++  Q    E++   M+AE+ +L+  
Sbjct: 1636 ANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRAS 1695

Query: 1689 LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI 1748
            L   ER ++ A+QE  + ++ +     +    +  K++LE  I+Q++ E+E+        
Sbjct: 1696 LERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNA 1755

Query: 1749 NDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKAS 1808
             ++ KKA      +  +L  E+  +   E  ++ +E+  K+L+++L E E       K  
Sbjct: 1756 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQ 1815

Query: 1809 ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKA 1868
            I  LEA++ +LE ++++E K    A K +R+ E+++K++  Q +++R+N  + +D  DK 
Sbjct: 1816 IQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL 1875

Query: 1869 STRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
             T++K  KRQ EEAEE++    A  RKLQ ELE+A E AD    +V+ L+ K R
Sbjct: 1876 QTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929



 Score =  253 bits (647), Expect = 1e-66
 Identities = 206/932 (22%), Positives = 440/932 (47%), Gaps = 57/932 (6%)

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI--- 1064
            L +  E  K +A +K + E      +E L + E +R+ELE+    L  +  DL  Q+   
Sbjct: 843  LLKSAETEKEMANMKEEFEKT----KEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898

Query: 1065 AELQAQIAELKMQLAKKEEELQAALARV-----EEEAAQKNMALKKIRELESQISELQED 1119
            A+  A   E   QL K + +L+A +  V     +EE     +  KK R+LE + SEL++D
Sbjct: 899  ADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKK-RKLEDECSELKKD 957

Query: 1120 LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
            ++    +  K EK+K     +++ L  E+   LD T A               K T E++
Sbjct: 958  IDDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIA---------------KLTKEKK 1001

Query: 1180 AKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQG 1239
            A         +++ H Q +++L  + ++   +     K +Q +++  G L  E K+ +  
Sbjct: 1002 A---------LQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCM-- 1050

Query: 1240 KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKL 1299
              D E  ++K+E  L+  Q    + E  + +L +K+ K + E+ N+ G +    + + +L
Sbjct: 1051 --DLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQL 1108

Query: 1300 TKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQI 1359
             K    L++++++ +E ++ E   +     +   +  E     E+LEE   A     +  
Sbjct: 1109 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMN 1168

Query: 1360 ATLHAQVADMKKKMEDSVGCLE-TAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418
                A+   M++ +E+S    E TA  +++K    +  L ++ +       KLEK K+ L
Sbjct: 1169 KKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSEL 1228

Query: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478
            + E++DL  +++   ++  N EK  +  +  L+E KT   +     +   A+     T++
Sbjct: 1229 KMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTES 1288

Query: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538
               +R L+E     ++L R  + F  ++E+L    ++  K+   L  + ++     + ++
Sbjct: 1289 GEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLR 1348

Query: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
             Q EE ++     +    +    +   + ++E D   R E+ EE KK+L +++++ E  +
Sbjct: 1349 EQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV 1408

Query: 1599 EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTR 1658
            E    + +     +++L+ +++DL   ++ +N       K+ R     + +  ++ ++T+
Sbjct: 1409 EAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQ 1468

Query: 1659 ASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGA 1718
            A  E    +++    +L  ++    +  + L   +R  +  QQE  +L ++IA   GK  
Sbjct: 1469 AELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEG-GKHI 1527

Query: 1719 LALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNE 1777
              LE+ K++L+   ++L+  LEE + + E    ++ +  L+++Q+ +++  +R  A+K+E
Sbjct: 1528 HELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEKDE 1585

Query: 1778 NARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNETKERQ 1831
                QL+R +  +   ++ M+ T+ ++ ++   AL  K      + ++E QL++  ++  
Sbjct: 1586 EL-DQLKRNHLRV---VESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAA 1641

Query: 1832 AACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANA 1891
             A + +R T+  LKD  L +DD  R  +  K+Q      R   ++ ++EE     +R   
Sbjct: 1642 EALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTER 1701

Query: 1892 SRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
             R+  ++EL DA+E    ++ + +SL N  ++
Sbjct: 1702 GRKMAEQELLDASERVQLLHTQNTSLINTKKK 1733



 Score =  209 bits (533), Expect = 2e-53
 Identities = 204/960 (21%), Positives = 440/960 (45%), Gaps = 120/960 (12%)

Query: 832  TKVKPLLQVSRQE--EEMMAKEEELVKVREKQLAAENRLTEMETLQSQ-------LMAEK 882
            TK K  LQ + Q+  +++  +E+++  + + +   E ++ ++E    Q       L   K
Sbjct: 997  TKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAK 1056

Query: 883  LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
             +L+  L+   E   + E  + +L  K ++ E    +L+ ++E+E+     LQ + K++Q
Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQ 1116

Query: 943  QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
              I+ELEE++E E ++R K + ++     +L+++ E    LE+     + + ++ + R A
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQIEMNKKREA 1173

Query: 1003 EFTTNLTEEEEKS----KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDST 1058
            EF     + EE +     + A L+ KH   + +L E++   ++ +Q+LEK + +L+ +  
Sbjct: 1174 EFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233

Query: 1059 DLSDQIAE--------------LQAQIAELKMQLAKKEE---ELQAALARVEEEAAQKNM 1101
            DL+  +                L+ Q++E+K +  +++    EL A  AR+  E+ + + 
Sbjct: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293

Query: 1102 ALKKIRELESQIS-----------ELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
             L +   + SQ+S           EL+  LE E  +++      +    + + L+ + E+
Sbjct: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE 1353

Query: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210
              ++ A  Q   SK   EV   +   E +A     +++E ++K +Q +++  E +E    
Sbjct: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413

Query: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
              A+LEK KQ L+NE  +L  +V+         + K++  +  L E + K+ E +     
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473

Query: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
               +   L  EL  V     +S      L ++   L+ ++ D  E + E  +    L   
Sbjct: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533

Query: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL-ETAEEVKRK 1389
             KQ++ EK+  +  LEE E +  + E +I  +  ++  +K +++  +    E  +++KR 
Sbjct: 1534 KKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRN 1593

Query: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQL 1449
              + +E +    + ++ + +   + K +++ +L+++ + L+H  + A    +  +    +
Sbjct: 1594 HLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGI 1653

Query: 1450 LAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQ-KAELERLNKQFRTEMED 1508
            L + +     + ++  R + + +E+       A  ++  +E+ +A LER  +  +   ++
Sbjct: 1654 LKDTQL----HLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQE 1709

Query: 1509 LMSSKDDVGKSVH----ELEKSKRALEQQVEEMKTQLEELEDELQATE--------DAKL 1556
            L+ + + V + +H     L  +K+ LE  + +++ ++E++  E +  E        DA +
Sbjct: 1710 LLDASERV-QLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAM 1768

Query: 1557 RLE---------VNLQAMKAQFE---RDLQGRDEQSEEK-----KKQLVR---QVREMEA 1596
              E          +L+ MK   E   +DLQ R +++E+      KKQ+ +   +VRE+E+
Sbjct: 1769 MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELES 1828

Query: 1597 ELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKN---------------------RDE 1635
            E+E E+K    AV   +K E  +K+L    +   KN                      +E
Sbjct: 1829 EVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEE 1888

Query: 1636 AIKQ-------LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
            A +Q        RKLQ ++++     D         +A+++ N+ ++KS E     + EE
Sbjct: 1889 AEEQSNVNLAKFRKLQHELEEAKERAD---------IAESQVNKLRVKSREVHTKVISEE 1939



 Score =  174 bits (441), Expect = 8e-43
 Identities = 143/693 (20%), Positives = 314/693 (45%), Gaps = 30/693 (4%)

Query: 1248 KKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALE 1307
            +K + +L + + K  E E     L  +   LQ+++      L+ ++ +  +L K    LE
Sbjct: 861  EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLE 920

Query: 1308 SQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVA 1367
            +++++  E  ++E      L+ K +++EDE +  ++ +++ E     +EK+    HA   
Sbjct: 921  AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE---KHATEN 977

Query: 1368 DMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA-------AYDKLEKTKTRLQQ 1420
             +K   E+  G  ET      KL K+ + L + H++ +          + L K KT+L+Q
Sbjct: 978  KVKNLTEEMAGLDETIA----KLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQ 1033

Query: 1421 ELDDLLVDLDHQRQSACNLEKKQKKF--DQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478
            ++DDL   L+ +++   +LE+ ++K   D  LA+E T+  +   ++ +   + ++KE + 
Sbjct: 1034 QVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTE--NDKQQLNEKLKKKEFEM 1091

Query: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538
             +L   +E+      +L++  K+ +  +E+L    +    S  + EK +  L +++EE+ 
Sbjct: 1092 SNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEIS 1151

Query: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
             +LEE      A  +   + E   Q M+   E      +  +   +K+    V E+  ++
Sbjct: 1152 ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQI 1211

Query: 1599 EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTR 1658
            +  ++ +      + +L+M++ DL +++++ +K +    K  R L+ Q+ +   + ++ +
Sbjct: 1212 DSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQ 1271

Query: 1659 ASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGA 1718
                E+ AQ      +      ++ +    ++   R K+   Q+ +EL  ++   +   +
Sbjct: 1272 RLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKS 1331

Query: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778
                  +        L E+ EEEQ     +   + KAN ++ Q  T    E    Q+ E 
Sbjct: 1332 TLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRT--KYETDAIQRTE- 1388

Query: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYK--ASITALEAKIAQLEEQLDNETKERQAAC-- 1834
               +LE   K+L  +LQ+ E  V++     AS+   + ++    E L  + +   AAC  
Sbjct: 1389 ---ELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIA 1445

Query: 1835 --KQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANAS 1892
              K+ R  +K L +   + ++ +   E  + ++   ST L ++K   EE+ +  +     
Sbjct: 1446 LDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRE 1505

Query: 1893 RRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
             + LQ+E+ D TE      + +  L+   ++ D
Sbjct: 1506 NKNLQQEISDLTEQIAEGGKHIHELEKVKKQLD 1538



 Score =  114 bits (285), Expect = 9e-25
 Identities = 118/579 (20%), Positives = 251/579 (43%), Gaps = 58/579 (10%)

Query: 828  WRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQE 887
            WR   +   + +    EE      + L    E   A  ++   +E  + +L  E   L  
Sbjct: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMI 1434

Query: 888  QLQAETELCAEAEELRAR----LTAKKQELEEICHDLEARVEEE--------------EE 929
             ++     C   ++ +      L   KQ+ EE   +LEA  +E               EE
Sbjct: 1435 DVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEE 1494

Query: 930  RCQHLQA---EKKKMQQNIQELEEQLEE-----EESARQKLQLEKVTTEAKLKKLEEEQI 981
               HL+    E K +QQ I +L EQ+ E      E  + K QL+   +E +   LEE + 
Sbjct: 1495 SLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTS-LEEAEA 1553

Query: 982  ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEK 1041
             LE +  K+ + +  L    +E    + E++E+   L +LK  H  ++  ++  L  E +
Sbjct: 1554 SLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE---LDQLKRNHLRVVESMQSTLDAEIR 1610

Query: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNM 1101
             R +  + ++K+EGD  ++  Q+     Q AE    L   +  L+     +++    ++ 
Sbjct: 1611 SRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDD 1670

Query: 1102 ALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQEL 1161
              +++  +E + + +Q ++E  RAS  + E+ ++   +EL          LD++   Q L
Sbjct: 1671 LKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQEL----------LDASERVQLL 1720

Query: 1162 RSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE----------LAEQLEQTKRV 1211
             ++    +N  KK LE +    + +++++ Q+   A E+          +AE+L++ +  
Sbjct: 1721 HTQNTSLINT-KKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDT 1779

Query: 1212 KANLEKAK----QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERV 1267
             A+LE+ K    QT+++ +  L    ++ L+G    + + +K+EA+++EL+ +    ++ 
Sbjct: 1780 SAHLERMKKNMEQTVKDLQLRLDEAEQLALKG---GKKQIQKLEARVRELESEVESEQKH 1836

Query: 1268 RTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSL 1327
              E    + K +  +  +T    +      +L      L+++++  +   +E   Q    
Sbjct: 1837 NVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVN 1896

Query: 1328 STKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
              K ++++ E    +E+ +  E   + L  +   +H +V
Sbjct: 1897 LAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKV 1935


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 1397 bits (3617), Expect = 0.0
 Identities = 772/1907 (40%), Positives = 1168/1907 (61%), Gaps = 26/1907 (1%)

Query: 28   AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
            AK   +V   K  +    +K     +  VE  E+ + + V  +D+  MNPPKF ++EDMA
Sbjct: 34   AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92

Query: 88   ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
             LT LNE +VL+NLK+RY S +IYTYSGLFCV +NPYK LP+Y+ E+VE Y+GKKR E P
Sbjct: 93   MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152

Query: 148  PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASS-----HKSKK 202
            PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A++      K  K
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212

Query: 203  DQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKS 262
             +G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLEKS
Sbjct: 213  MKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 272

Query: 263  RAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDMFQ 320
            R   Q K ER++HIFY +LS     L   LL+   PY+ Y F+S G + +    D +   
Sbjct: 273  RVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYD-YPFISQGEILVASIDDAEELL 331

Query: 321  ETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGI 380
             T  A+ I+G   EE+ GL ++   V+  GN+ FK+++  +QA       A K ++L+G+
Sbjct: 332  ATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGL 391

Query: 381  NVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKT 440
            N +D  + +  PR+KVG +YV K QT +Q   A+ AL+K+ YE++F W+V RIN+ LD T
Sbjct: 392  NSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLD-T 450

Query: 441  KRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 500
            K     FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW 
Sbjct: 451  KLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 510

Query: 501  FIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQKP 559
            FIDFG+DL  CI+LIEKP G   I ++L+EEC FPKATD SF  K+  Q  G    FQKP
Sbjct: 511  FIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKP 567

Query: 560  KQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDR 617
            K +K +A+  F +IHYAG VDY    WL KN DPLN+ +  L  +SS++ ++ L+     
Sbjct: 568  KVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYAT--- 624

Query: 618  IIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHE 677
                D  +G  + A     K +   F+TV  L++E L KLM+ LR T+P+FVRCIIPN  
Sbjct: 625  FATADADSGKKKVA-----KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNET 679

Query: 678  KKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDG 736
            K  G ++  LVL QLRCNGVLEGIRICR+GFPNR+++ +F+QRY +L  ++IP+G F+D 
Sbjct: 680  KTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDS 739

Query: 737  KQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLAR 796
            K+AC  ++ ++++D   Y+ G +KVFF+AG+L  LEE RD ++  +I   QA CRG+L R
Sbjct: 740  KKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMR 799

Query: 797  KAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVK 856
              F K  Q+  ++  +Q N  +++ +++W W +LF K+KPLL+ +  E+EM   +EE  K
Sbjct: 800  VEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQK 859

Query: 857  VREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEI 916
             +++   +E +  E+E     L+ EK  LQ Q+QAE+E   +AEE   +L   K +LE  
Sbjct: 860  TKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAK 919

Query: 917  CHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKL 976
              ++  R E+EEE    L A+K+K++    EL++ +++ E    K++ EK  TE K+K L
Sbjct: 920  IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 979

Query: 977  EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
             EE   L++   KL +EKK L++   +   +L  EE+K  SL K K+K E  + DLE  L
Sbjct: 980  TEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSL 1039

Query: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
             +E+K R +LE+ +RKLEGD     + I +L+    +L  +L KK+ E     ++VE+E 
Sbjct: 1040 EQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQ 1099

Query: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
                   KKI+EL+++I EL+E++E+ERA+R K EKQ+ D   ELE L   LE+    T+
Sbjct: 1100 TLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTS 1159

Query: 1157 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216
             Q EL  KRE E   L++ LEE    HEA +  +R+KH+ +V EL EQ++  +RVK  LE
Sbjct: 1160 TQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLE 1219

Query: 1217 KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276
            K K   + E  +L++ ++ + + K + E   + +E QL E + K  E +R  +EL  + +
Sbjct: 1220 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 1279

Query: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336
            +LQ E   ++  L + +S  S+L++   A   Q ++ +  L+EEN+ K +L+  L+    
Sbjct: 1280 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 1339

Query: 1337 EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKDLE 1395
            + +  REQ EEE+E K  L++ ++  +++VA  + K E D++   E  EE K+KL + L+
Sbjct: 1340 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1399

Query: 1396 GLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
               ++ E   A    LEKTK RLQ E++DL+VD++     A  L+KKQ+ FD++LAE KT
Sbjct: 1400 DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKT 1459

Query: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDD 1515
               +   E + +  E+R   T+   L  A EEA++Q   ++R NK    E+ DL     +
Sbjct: 1460 KCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAE 1519

Query: 1516 VGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
             GK++HELEKS++ +E +  +++  LEE E  L+  E   LR+++ L  +K++ +R +  
Sbjct: 1520 NGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAE 1579

Query: 1576 RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDE 1635
            +DE+ E+ K+   R V  M++ L+ E + R+ A+  +KK+E DL ++E  +  AN+   E
Sbjct: 1580 KDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAE 1639

Query: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
             +K LR +Q Q+KD    LDD    +E++  Q    E++   ++AE+ +L+  L   ERA
Sbjct: 1640 TLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA 1699

Query: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
            ++ A+QE  +  + +     +    +  K++LE  + QL+ E+E+   +     ++ KKA
Sbjct: 1700 RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKA 1759

Query: 1756 NLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK 1815
                  +  +L  E+  +   E  ++ LE+  K+L+ +L E E       K  I  LE +
Sbjct: 1760 ITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETR 1819

Query: 1816 IAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQL 1875
            I +LE +L+ E K+   + K +R+ E+++K++  Q +++R+N  + +D  DK   ++K  
Sbjct: 1820 IRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSY 1879

Query: 1876 KRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            KRQ EEA+E+A       RK Q ELE+A E AD    +V+ L+ K R
Sbjct: 1880 KRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926



 Score =  157 bits (397), Expect = 1e-37
 Identities = 142/642 (22%), Positives = 288/642 (44%), Gaps = 43/642 (6%)

Query: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
            KS++  K+ + ++ + Q T++ L +   ++  L  KL  +  EKN  + Q++ E E   +
Sbjct: 842  KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901

Query: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
             E++   L      ++ K+++     E  EE+  +L               A   KLE  
Sbjct: 902  AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAEL--------------TAKKRKLEDE 947

Query: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
             + L++++DDL + L    +     E K K   + L+      AK   E+ +A  EA ++
Sbjct: 948  CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREK-KALQEAHQQ 1006

Query: 1475 ETKALSLARALEEAMEQKAELERLNK---QFRTEMEDLMSSKDDVGKSVHELEKSKRALE 1531
                     AL++   ++ ++  LNK   +   ++EDL SS +   K   +LE++KR LE
Sbjct: 1007 ---------ALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLE 1057

Query: 1532 QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQV 1591
              ++  +  + +LE++ Q  ++   + +     ++++ E D Q    Q ++K K+L  ++
Sbjct: 1058 GDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVE-DEQTLGLQFQKKIKELQARI 1116

Query: 1592 REMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCM 1651
             E+E E+E ER  R+     R     +L++L   ++ A       I+  +K +A+     
Sbjct: 1117 EELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLR 1176

Query: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
            R+L++     E ++A  +      K     + +L E++   +R K++ ++E+ E   EI 
Sbjct: 1177 RDLEEATLQHEAMVAALR------KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEID 1230

Query: 1712 NSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERS 1771
            + S       + K  LE     LE++L E +G  E I   L +   Q  ++ T+      
Sbjct: 1231 DLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSR 1290

Query: 1772 HAQKNENARQQLER-------QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
              ++ E+   QL R       Q +ELK +L+E E   K+    ++ +       L EQ +
Sbjct: 1291 QLEEKESIVSQLSRSKQAFTQQTEELKRQLEE-ENKAKNALAHALQSSRHDCDLLREQYE 1349

Query: 1825 NETKERQAACKQVRRTEKKLKDVLLQVD-DERRNAEQYKDQADKASTRLKQLKRQLEEAE 1883
             E + +    + + +   ++     + + D  +  E+ ++   K + RL+  + Q+E   
Sbjct: 1350 EEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVN 1409

Query: 1884 EEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
             +      ++++LQ E+ED     +  N   ++L  K R  D
Sbjct: 1410 AKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFD 1451



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 31/305 (10%)

Query: 859  EKQLAAENR-----LTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQEL 913
            E QL+  NR     L  + ++Q QL   +L L + L+ + +L  +   +  R    + E+
Sbjct: 1627 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 1686

Query: 914  EEICHDLEA-----RVEEEE-----ERCQHLQAE-------KKKMQQNIQELEEQLEE-- 954
            EE+   LE      ++ E+E     ER Q L  +       KKK++ ++ +L+ ++E+  
Sbjct: 1687 EELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDAS 1746

Query: 955  EESARQKLQLEKVTTEAKL--KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE 1012
             ++   + + +K  T+A +  ++L++EQ    D +  L + KK LE  + +    L E E
Sbjct: 1747 RDARNAEEKAKKAITDAAMMAEELKKEQ----DTSAHLERMKKNLEQTVKDLQHRLDEAE 1802

Query: 1013 EKS-KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI 1071
            + + K   K   K E  I +LE  L  E+K+  E  K  RK E    +L+ Q  E +  +
Sbjct: 1803 QLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNV 1862

Query: 1072 AELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAE 1131
              L+  + K + ++++   + EE   Q N  L K R+ + ++ E +E  +   +  NK  
Sbjct: 1863 LRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLR 1922

Query: 1132 KQKRD 1136
             + RD
Sbjct: 1923 AKTRD 1927



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 64/273 (23%), Positives = 131/273 (47%), Gaps = 33/273 (12%)

Query: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724
            L ++ E EK++ +M+ E  + ++ELA +E AKR+  +E             K    ++EK
Sbjct: 840  LLKSAETEKEMATMKEEFQKTKDELAKSE-AKRKELEE-------------KLVTLVQEK 885

Query: 1725 RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENA----- 1779
              L+ ++    E L + +       D+L KA  Q++    ++  ER+  ++  NA     
Sbjct: 886  NDLQLQVQAESENLLDAEERC----DQLIKAKFQLEAKIKEVT-ERAEDEEEINAELTAK 940

Query: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRR 1839
            +++LE +  ELK  + ++E T+ +K +    A E K+  L E+L            ++ R
Sbjct: 941  KRKLEDECSELKKDIDDLELTL-AKVEKEKHATENKVKNLTEELSG----LDETIAKLTR 995

Query: 1840 TEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANA----SRRK 1895
             +K L++   Q  D+ +  E   +  +K  ++L+Q    LE + E+ ++       ++RK
Sbjct: 996  EKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055

Query: 1896 LQRELEDATETADAMNREVSSLKNKLRRGDLPF 1928
            L+ +L+ A E+   +  +   L  +L++ D  +
Sbjct: 1056 LEGDLKLAQESILDLENDKQQLDERLKKKDFEY 1088



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 65/293 (22%), Positives = 113/293 (38%), Gaps = 25/293 (8%)

Query: 834  VKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAET 893
            +K  L +  +   ++  E E ++   +Q     +L E E L S    + L  Q      T
Sbjct: 1668 LKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHT 1727

Query: 894  ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
                            K++LE     L++ VE+     ++ + + KK   +   + E+L+
Sbjct: 1728 ----------------KKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELK 1771

Query: 954  EEESARQKLQLEKVTTEAKLKKL-----EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNL 1008
            +E+     L+  K   E  +K L     E EQ+ L+    ++ K    LE RI E    L
Sbjct: 1772 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK----LETRIRELEFEL 1827

Query: 1009 TEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQ 1068
              E++K+    K   K+E  + +L  +   + K    L+    KL+        Q  E  
Sbjct: 1828 EGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEAD 1887

Query: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE 1121
             Q      +  K + EL+ A  R +   +Q N    K R+  S    + E  E
Sbjct: 1888 EQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1940


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 1374 bits (3557), Expect = 0.0
 Identities = 762/1912 (39%), Positives = 1156/1912 (60%), Gaps = 33/1912 (1%)

Query: 28   AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
            +KK  +V  +K  +    ++    ++ IV+ +++ + + +N D +  MNPPKF K+EDMA
Sbjct: 34   SKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKFDKIEDMA 92

Query: 88   ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
             +T L+E +VL+NLKERY + +IYTYSGLFCV +NPYK LP+Y  E+V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 152

Query: 148  PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD---- 203
            PHI++I+D AY+ M+ DR++QSIL TGESGAGKT NTK+VIQY A +A +   KK+    
Sbjct: 153  PHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPG 212

Query: 204  --QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEK 261
              QG LE Q++QANP+LEAFGNAKTV+NDNSSRFGKFIRI+F   G +  A+IETYLLEK
Sbjct: 213  KMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEK 272

Query: 262  SRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRF--LSNGHVTIPGQQDKDMF 319
            SR   Q   ER++HIFY ++S     L  DLLL   N + F  +S G VT+    D +  
Sbjct: 273  SRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVASIDDSEEL 331

Query: 320  QETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLG 379
              T  A+ I+G   EE++G+ ++   V+  GN+ FK+++  +QA       A K  +L+G
Sbjct: 332  LATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMG 391

Query: 380  INVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDK 439
            +N  +  +G+  PR+KVG +YV K Q  +Q   ++ ALAKA YE+MF W+V RIN+ LD 
Sbjct: 392  LNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD- 450

Query: 440  TKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 499
            TK+    FIG+LDIAGFEIFD NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 451  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 510

Query: 500  NFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQK 558
             FIDFG+DL  CI+LIEKP G   I ++L+EEC FPKATD SF  K+  Q  G    FQK
Sbjct: 511  EFIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 567

Query: 559  PKQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVD 616
            PK  K KA+  F ++HYAG VDY    WL KN DPLN+ +  L  +SS K +S L+ +  
Sbjct: 568  PKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNY- 626

Query: 617  RIIGLDQVAGMSETALPGAFKT---RKGM-FRTVGQLYKEQLAKLMATLRNTNPNFVRCI 672
                    AG +ET   G  K    +KG  F+TV  +++E L KLM  LR+T+P+FVRC+
Sbjct: 627  --------AG-AETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCL 677

Query: 673  IPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG 732
            IPN  K  G +D +LV+ QLRCNGVLEGIRICR+GFP+R+++ +F+QRY IL  ++IP+G
Sbjct: 678  IPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEG 737

Query: 733  -FMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCR 791
             F+D K A   ++ ++++D   +R G +KVFF+AG+L  LEE RD K+  ++   QA CR
Sbjct: 738  QFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCR 797

Query: 792  GYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKE 851
            GYL R  F K  ++  ++  +Q N  +++ +++W W  LF K+KPLL+ +  E+EM   +
Sbjct: 798  GYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMK 857

Query: 852  EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQ 911
            E+  + +E+   +E R  E+E     L+ EK  LQ Q+Q+ETE   +AEE    L   K 
Sbjct: 858  EDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKI 917

Query: 912  ELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEA 971
             LE    +L  R+EEEEE    L A+K+ ++     L+  +++ E    K++ EK  TE 
Sbjct: 918  LLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATEN 977

Query: 972  KLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD 1031
            K+K L EE   LE+   KL KEKK L++   +   +L  EE+K   L K+  K E    D
Sbjct: 978  KVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDD 1037

Query: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
            LE  L +E+K R +LE+ +RKLEGD     + I +L+    +++ +L KKE EL    A+
Sbjct: 1038 LEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAK 1097

Query: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
            +++E        KKI+EL+++I EL+E++E+E   R K EKQ+ DL  ELE +   LE+ 
Sbjct: 1098 IDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157

Query: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211
              +T+AQ E+  KRE E   +++ LEE    HEA    +R+K + +V EL EQ++  +RV
Sbjct: 1158 SGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRV 1217

Query: 1212 KANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTEL 1271
            K  LEK K  L+ E  ++A+ ++ L + K + E   + VE Q  E++ K  +  ++  +L
Sbjct: 1218 KQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDL 1277

Query: 1272 ADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL 1331
              +  +LQ +   ++  + + +S  S+LTK   AL  QL++ +  ++EE + K +++  L
Sbjct: 1278 NMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHAL 1337

Query: 1332 KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKL 1390
            +    + +  REQ EEE+EAK  L++ ++  +++VA  + K E D++   E  EE K+KL
Sbjct: 1338 QSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1397

Query: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLL 1450
             + L+   +  E   +    LEKTK RLQ E++DL+ DL+    +   L+KKQ+ FD++L
Sbjct: 1398 AQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVL 1457

Query: 1451 AEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLM 1510
            AE K    +   E + A+ E+R   T+   +  A EE ++Q   L R NK  + E+ DL 
Sbjct: 1458 AEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLT 1517

Query: 1511 SSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570
                + GK++ E EK+K+ +EQ+  +++  LEE+E  L+  E   LR+++ L  +K++ +
Sbjct: 1518 EQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELD 1577

Query: 1571 RDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630
            R +  +DE+ E+ K+   R    +++ L+ E + R+ A+  +KK+E DL ++E  +  +N
Sbjct: 1578 RKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSN 1637

Query: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 1690
            +   E  K LR +Q Q+KD    LDD   S E++  Q    E++   +  E+ +++  L 
Sbjct: 1638 RQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALE 1697

Query: 1691 AAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 1750
              ER +R ++QE  + +D +     +    +  K++LEA IAQ + E+E     +    +
Sbjct: 1698 QTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEE 1757

Query: 1751 RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810
            + KKA      +  +L  E+  +   E  ++ LE+  K+L+ +L E E       K  I 
Sbjct: 1758 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1817

Query: 1811 ALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAST 1870
             LE ++ +LE +LD E K    A K   + E+K+K++  Q +++ +N  + +D  DK   
Sbjct: 1818 KLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQA 1877

Query: 1871 RLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            ++K  KRQ EEAEE+A    +  R++Q ELE+A E AD    +V+ L+ K R
Sbjct: 1878 KVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSR 1929



 Score =  249 bits (635), Expect = 2e-65
 Identities = 227/964 (23%), Positives = 445/964 (46%), Gaps = 121/964 (12%)

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI--- 1064
            L +  E  K +A +K   E      +E L R E +R+ELE+    L  +  DL  Q+   
Sbjct: 843  LLKSAEAEKEMATMKEDFERT----KEELARSEARRKELEEKMVSLLQEKNDLQLQVQSE 898

Query: 1065 ------AELQAQ-IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQ 1117
                  AE + + + + K+ L  K +EL     R+EEE    +  + K R LE + S L+
Sbjct: 899  TENLMDAEERCEGLIKSKILLEAKVKELTE---RLEEEEEMNSELVAKKRNLEDKCSSLK 955

Query: 1118 EDLESERASRNKAEKQK-------RDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170
             D++    +  K EK+K       ++L EE+ AL+  +        + QE   +   ++ 
Sbjct: 956  RDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQ 1015

Query: 1171 ILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELA 1230
            +      EE K +   + ++  K  Q  ++L   LEQ K+++A+LE+AK+ LE +     
Sbjct: 1016 V------EEDKVNG--LIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQ 1067

Query: 1231 NEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLS 1290
              +  L   K   E K KK E +L +LQ K ++ +    +   K+ +LQ  ++ +   + 
Sbjct: 1068 ESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIE 1127

Query: 1291 QSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE 1350
               +  +K+ K  S L  +L++  E L+E        ++     + E N  RE   E ++
Sbjct: 1128 AEHTLRAKIEKQRSDLARELEEISERLEE--------ASGATSAQIEMNKKREA--EFQK 1177

Query: 1351 AKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDK 1410
             + +LE+      A  A ++KK  DSV   E  E++      +L+ + Q          K
Sbjct: 1178 MRRDLEEATLQHEATAATLRKKQADSVA--ELGEQID-----NLQRVKQ----------K 1220

Query: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
            LEK K+ L+ E+DD+  +++   +S  N+E+  +          T+  +++E + + E +
Sbjct: 1221 LEKEKSELKMEIDDMASNIEALSKSKSNIERTCR----------TVEDQFSEIKAKDEQQ 1270

Query: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
             +            + +   QKA L+  N +    +E+  S        + +L KSK+AL
Sbjct: 1271 TQ-----------LIHDLNMQKARLQTQNGELSHRVEEKESL-------ISQLTKSKQAL 1312

Query: 1531 EQQVEEMKTQLEE---------------------LEDELQATEDAKLRLEVNLQAMKAQ- 1568
             QQ+EE+K Q+EE                     L ++ +  ++AK  L+  L    ++ 
Sbjct: 1313 TQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEV 1372

Query: 1569 ------FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDL 1622
                  +E D   R E+ EE KK+L ++++E E   E    + +     +++L+ +++DL
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDL 1432

Query: 1623 EAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 1682
               ++ ++       K+ R     + +  ++LD+++A  E    +++    +L  M    
Sbjct: 1433 MRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAY 1492

Query: 1683 IQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQ 1742
             ++ ++L    R  +  Q+E  +L ++IA +      A + K+ +E   + L+  LEE +
Sbjct: 1493 EEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVE 1552

Query: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQE-MEGTV 1801
            G+ E    ++ +  L++ Q+ ++L  +R   +K+E   +QL+R ++     LQ  ++  +
Sbjct: 1553 GSLEHEESKILRVQLELSQVKSEL--DRKVIEKDEEI-EQLKRNSQRAAEALQSVLDAEI 1609

Query: 1802 KSKYKASITA--LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAE 1859
            +S+  A      +E  + ++E QL +  ++     K +R  + +LKD  L +DD  R+ E
Sbjct: 1610 RSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNE 1669

Query: 1860 QYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKN 1919
              K+Q      R   L  +LEE +   ++   +RR  ++EL DA++    ++ + +SL N
Sbjct: 1670 DLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLIN 1729

Query: 1920 KLRR 1923
              ++
Sbjct: 1730 TKKK 1733



 Score =  192 bits (487), Expect = 4e-48
 Identities = 197/847 (23%), Positives = 370/847 (43%), Gaps = 83/847 (9%)

Query: 838  LQVSRQEEEMMAKEEELVKVREKQLAAENRL-TEMETLQSQLMAEKLQLQEQLQAETELC 896
            LQ  ++ +E+ A+ EEL    E+++ AE+ L  ++E  +S L  E  ++ E+L+  +   
Sbjct: 1106 LQFQKKIKELQARIEEL----EEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGAT 1161

Query: 897  AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
            +   E+  +   ++ E +++  DLE    + E     L   +KK   ++ EL EQ++  +
Sbjct: 1162 SAQIEMNKK---REAEFQKMRRDLEEATLQHEATAATL---RKKQADSVAELGEQIDNLQ 1215

Query: 957  SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE----- 1011
              +QKL+ EK   + ++  +      L      + +  + +ED+ +E      ++     
Sbjct: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIH 1275

Query: 1012 --------------------EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR 1051
                                EEK   +++L    +A+   LEE  R+ E++ +       
Sbjct: 1276 DLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAH 1335

Query: 1052 KLEGDSTD---LSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRE 1108
             L+    D   L +Q  E Q   AEL+  L+K   E+     + E +A Q+   L++ ++
Sbjct: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395

Query: 1109 -LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
             L  ++ E +E+ E+  +     EK K+ L  E+E L  +LE +  + A   + +   ++
Sbjct: 1396 KLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDK 1455

Query: 1168 EVNILKKTLEEEAKTHEAQIQEMRQ------KHSQAVEELAEQLEQTKRVKANLEKAKQT 1221
             +   K+ L+E     EA  +E R       K   A EE+ +QLE  +R   NL++    
Sbjct: 1456 VLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISD 1515

Query: 1222 LENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVE 1281
            L  +  E    ++       ++E  +K VE +  +LQV   E E        K+ ++Q+E
Sbjct: 1516 LTEQIAETGKNLQ-------EAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLE 1568

Query: 1282 LDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE----ENRQKLSLSTKLKQVEDE 1337
            L  V    S+ D K  +  ++   L+   Q   E LQ     E R +       K++E +
Sbjct: 1569 LSQVK---SELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGD 1625

Query: 1338 KNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGL 1397
             N    QL          +K + T+  Q+ D +  ++D++   E  +E    +++    L
Sbjct: 1626 LNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLL 1685

Query: 1398 SQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTIS 1457
             +  EE   A ++ E+T+   +QEL D    +        +L   +KK +  +A+ +   
Sbjct: 1686 LEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745

Query: 1458 AKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG 1517
                +E   AE +A++  T A  +A  L++  +  A LER+ K     ++DL    D+  
Sbjct: 1746 ENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1805

Query: 1518 --------KSVHELEKSKRALEQQVE-EMKTQLEEL-----------EDELQATEDAK-- 1555
                    K + +LE   R LE +++ E K   E L           E   QA ED K  
Sbjct: 1806 QLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNI 1865

Query: 1556 LRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKL 1615
            LRL+  +  ++A+ +   +  +E  E+   QL R  R ++ ELE+  ++  +A +   KL
Sbjct: 1866 LRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSR-CRRVQHELEEAAERADIAESQVNKL 1924

Query: 1616 EMDLKDL 1622
                +D+
Sbjct: 1925 RAKSRDV 1931



 Score =  157 bits (398), Expect = 7e-38
 Identities = 142/661 (21%), Positives = 296/661 (44%), Gaps = 81/661 (12%)

Query: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
            KS++  K+ + ++   + T+E L     ++  L  K+  +  EKN  + Q++ E E    
Sbjct: 845  KSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE---- 900

Query: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
                       + D +++ E  +      E   ++L + LE   + + E VA    LE  
Sbjct: 901  ----------NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDK 950

Query: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKF-DQLLAEEKTISAKYAEERDRAEAEARE 1473
             + L++++DDL + L    +     E K K   +++ A E+ IS    E++   EA  + 
Sbjct: 951  CSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQT 1010

Query: 1474 KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
             +         L+   ++   L ++N +   + +DL  S +   K   +LE++KR LE  
Sbjct: 1011 LDD--------LQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGD 1062

Query: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
            ++  +  + +LE++ Q  E+   + E  L  ++A+ + D Q    Q ++K K+L  ++ E
Sbjct: 1063 LKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKID-DEQVHSLQFQKKIKELQARIEE 1121

Query: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
            +E E+E E   R+     R  L  +L+++   ++ A+      I+  +K +A+ +   R+
Sbjct: 1122 LEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRD 1181

Query: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
            L++     E   A  +      K     + +L E++   +R K++ ++E+ EL  EI + 
Sbjct: 1182 LEEATLQHEATAATLR------KKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDM 1235

Query: 1714 SGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHA 1773
            +       + K  +E     +E++  E           +K  + Q  Q+  DLN++++  
Sbjct: 1236 ASNIEALSKSKSNIERTCRTVEDQFSE-----------IKAKDEQQTQLIHDLNMQKA-- 1282

Query: 1774 QKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAA 1833
                    +L+ QN EL  +++E E  + S+   S  AL  ++ +L+ Q++ ETK + A 
Sbjct: 1283 --------RLQTQNGELSHRVEEKESLI-SQLTKSKQALTQQLEELKRQMEEETKAKNAM 1333

Query: 1834 CKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRL--------------------- 1872
               ++ +      +  Q ++E+    + +    KA++ +                     
Sbjct: 1334 AHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1393

Query: 1873 -KQLKRQLEEAEEEAQRANA-------SRRKLQRELEDATETADAMNREVSSLKNKLRRG 1924
             K+L ++L+EAEE  + AN+       ++++LQ E+ED     +  +   ++L  K R  
Sbjct: 1394 KKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNF 1453

Query: 1925 D 1925
            D
Sbjct: 1454 D 1454



 Score =  152 bits (385), Expect = 2e-36
 Identities = 160/706 (22%), Positives = 316/706 (44%), Gaps = 38/706 (5%)

Query: 852  EELVKVREKQLAAENRLTEMET-LQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKK 910
            E   +  E Q +      E +T L   L  +K +LQ Q    +    E E L ++LT  K
Sbjct: 1250 ERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSK 1309

Query: 911  QELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ--LEKVT 968
            Q L +   +L+ ++EEE +    +    +  + +   L EQ EEE+ A+ +LQ  L K  
Sbjct: 1310 QALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKAN 1369

Query: 969  TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAM 1028
            +E    + + E   ++    +L + KK L  R+ E   N      K  SL K K + +  
Sbjct: 1370 SEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGE 1428

Query: 1029 ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAA 1088
            + DL   L R       L+K +R  +    +   ++ E QA++   + +      EL   
Sbjct: 1429 VEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKM 1488

Query: 1089 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 1148
                EE   Q     ++ + L+ +IS+L E +     +  +AEK K+ + +E   L+  L
Sbjct: 1489 RNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVAL 1548

Query: 1149 EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT 1208
            E+   S   ++    + + E++ +K  L+ +    + +I+++++   +A E L   L+  
Sbjct: 1549 EEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAE 1608

Query: 1209 KRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVR 1268
             R + +  + K+ +E +  E+  ++    +   +++   + V+ QL++ Q+  ++  R  
Sbjct: 1609 IRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSN 1668

Query: 1269 TELADKVTKLQ-------VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN 1321
             +L +++  ++        EL+ +   L Q++ ++ +L+      E +L D  + +Q  +
Sbjct: 1669 EDLKEQLAIVERRNGLLLEELEEMKVALEQTE-RTRRLS------EQELLDASDRVQLLH 1721

Query: 1322 RQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE---KQIATLHAQVADMKKKMEDSVG 1378
             Q  SL    K++E +    + ++E   +   N E   K+  T  A +A+  KK +D+  
Sbjct: 1722 SQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSA 1781

Query: 1379 CLETAEEVKRKLQKDLEGLSQRHEE-KVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC 1437
             LE    +K+ L++ ++ L  R +E +  A    +K   +L+  + +L  +LD +++   
Sbjct: 1782 HLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGA 1838

Query: 1438 NLEKKQKKFDQLLAEEKTISAKYAEERD-----RAEAEAREKETKALSLARALEEAMEQ- 1491
               K   K+     E K     Y  E D     R +    + + K  S  R  EEA EQ 
Sbjct: 1839 EALKGAHKY-----ERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQA 1893

Query: 1492 KAELERLNKQFRTEMEDLMSSKDDVGKSVHELE-KSKRALEQQVEE 1536
              +L R  ++ + E+E+     D     V++L  KS+    Q++EE
Sbjct: 1894 NTQLSRC-RRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938



 Score =  119 bits (297), Expect = 4e-26
 Identities = 118/557 (21%), Positives = 249/557 (44%), Gaps = 27/557 (4%)

Query: 795  ARKAFAKRQQQLTA-MKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEE 853
            A+K  A+R Q+     +     CA+  K +     RL  +V+ L++   +     A  ++
Sbjct: 1393 AKKKLAQRLQEAEENTETANSKCASLEKTKQ----RLQGEVEDLMRDLERSHTACATLDK 1448

Query: 854  LVKVREKQLAA-----ENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTA 908
              +  +K LA      +    E+E  Q +  +   +L +   A  E+  + E LR     
Sbjct: 1449 KQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKN 1508

Query: 909  KKQELEEICHDLEA---RVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA--RQKLQ 963
             ++E+ ++   +      ++E E+  + ++ EK  +Q  ++E+E  LE EES   R +L+
Sbjct: 1509 LQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLE 1568

Query: 964  LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA-KLK 1022
            L +V +E   K +E+++ I         ++ K    R AE   ++ + E +S++ A +LK
Sbjct: 1569 LSQVKSELDRKVIEKDEEI---------EQLKRNSQRAAEALQSVLDAEIRSRNDALRLK 1619

Query: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
             K E  + ++E +L    +Q  E +K  R ++G   D    + +      +LK QLA  E
Sbjct: 1620 KKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVE 1679

Query: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELE 1142
                  L  +EE         +  R  E ++ +  + ++   +        K+ L  ++ 
Sbjct: 1680 RRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIA 1739

Query: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELA 1202
              + E+E+++  +   +E   K   +  ++ + L++E  T  A ++ M++   Q V++L 
Sbjct: 1740 QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDT-SAHLERMKKNLEQTVKDLQ 1798

Query: 1203 EQLEQTKRVKANLEKAK-QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKF 1261
             +L++ +++     K + Q LEN   EL NE+ V  +   ++     K E +++E+  + 
Sbjct: 1799 HRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQA 1858

Query: 1262 NEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN 1321
             E  +    L D V KLQ ++ +      +++ +++        ++ +L++  E      
Sbjct: 1859 EEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAE 1918

Query: 1322 RQKLSLSTKLKQVEDEK 1338
             Q   L  K + V  +K
Sbjct: 1919 SQVNKLRAKSRDVGSQK 1935



 Score =  115 bits (289), Expect = 3e-25
 Identities = 122/589 (20%), Positives = 261/589 (44%), Gaps = 66/589 (11%)

Query: 828  WRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQE 887
            WR   +   + +    EE      + L +  E    A ++   +E  + +L  E   L  
Sbjct: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMR 1434

Query: 888  QLQAETELCAEAEELRAR----LTAKKQELEEICHDLEAR-----------------VEE 926
             L+     CA  ++ +      L   KQ+L+E   +LEA                   EE
Sbjct: 1435 DLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEE 1494

Query: 927  EEERCQHLQAEKKKMQQNIQELEEQLEE-----EESARQKLQLEKVTTEAKLKKLEEEQI 981
              ++ + L+ E K +Q+ I +L EQ+ E     +E+ + K  +E+  ++ ++  LEE + 
Sbjct: 1495 VVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVA-LEEVEG 1553

Query: 982  ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEK 1041
             LE +  K+ + +  L    +E    + E++E+   + +LK   +     L+  L  E +
Sbjct: 1554 SLEHEESKILRVQLELSQVKSELDRKVIEKDEE---IEQLKRNSQRAAEALQSVLDAEIR 1610

Query: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNM 1101
             R +  + ++K+EGD  ++  Q+     Q+AE +  L   + +L+ +   +++       
Sbjct: 1611 SRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNED 1670

Query: 1102 ALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQEL 1161
              +++  +E +   L E+LE  + +  + E+ +R   +EL          LD++   Q L
Sbjct: 1671 LKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQEL----------LDASDRVQLL 1720

Query: 1162 RSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE----------LAEQLEQTKRV 1211
             S+    +N  KK LE +    +A+++   Q+   A E+          +AE+L++ +  
Sbjct: 1721 HSQNTSLINT-KKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDT 1779

Query: 1212 KANLEKAKQTLENERGELANEV----KVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERV 1267
             A+LE+ K+ LE    +L + +    ++ L+G    + + +K+E +++EL+ + +  ++ 
Sbjct: 1780 SAHLERMKKNLEQTVKDLQHRLDEAEQLALKG---GKKQIQKLENRVRELENELDVEQKR 1836

Query: 1268 RTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSL 1327
              E      K + ++  +T    +      +L      L+++++  +   +E   Q  + 
Sbjct: 1837 GAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQ 1896

Query: 1328 STKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADM-KKKMED 1375
             ++ ++V+ E       LEE  E     E Q+  L A+  D+  +KME+
Sbjct: 1897 LSRCRRVQHE-------LEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 1370 bits (3546), Expect = 0.0
 Identities = 773/1918 (40%), Positives = 1151/1918 (60%), Gaps = 35/1918 (1%)

Query: 26   WAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVED 85
            W  KK VWVP ++  +  A +K E     +    ++ K + V + ++Q MNPP+F  +ED
Sbjct: 71   WDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQKVLMVREAELQPMNPPRFDLLED 130

Query: 86   MAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHE 145
            MA +T LNEASVLHNL++RY   +IYTYSGLFCV INPYK LP+Y+  +V  YKGK+R +
Sbjct: 131  MAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRSD 190

Query: 146  MPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS--------- 196
             PPHIYA+ D AY  M+++R++QS+L TGESGAGKT NTK+VIQY A VA+         
Sbjct: 191  SPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKKA 250

Query: 197  SHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIET 256
               + K  G LE Q+++ANP +EAFGNAKT++NDNSSRFGKFIRI+F  +G +  A+I++
Sbjct: 251  QFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADIDS 310

Query: 257  YLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLE--PYNKYRFLSNGHVTIPGQQ 314
            YLLEKSR I Q   ER++H++Y +LSG    L+  LLL   PY+ Y F S G +T+    
Sbjct: 311  YLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYD-YHFCSQGVITVDNMN 369

Query: 315  DKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKV 374
            D +    T  AM I+G   +E+    +++  +L  GN+ FK+++  +QA      +A K 
Sbjct: 370  DGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKA 429

Query: 375  SHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRIN 434
            ++L+G++  D  +G+L PR++VG +YV K Q+ EQ  FA+ ALAKATY+R+FRWLV RIN
Sbjct: 430  AYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRIN 489

Query: 435  KALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQR 494
            + LD TK     FIG+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FN  MF+LEQEEY+R
Sbjct: 490  QTLD-TKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKR 548

Query: 495  EGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQ-GTH 553
            EGI+W FIDFGLDLQPCIDLIEKP G   IL++L+EEC FPKA+D SF  K+     G  
Sbjct: 549  EGIDWVFIDFGLDLQPCIDLIEKPLG---ILSILEEECMFPKASDASFRAKLYDNHAGKS 605

Query: 554  PKFQKP---KQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSE 610
            P FQ+P   K+ K +A F ++HYAG V Y    WL KN DPLN+ +  +  +S ++ ++ 
Sbjct: 606  PNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLAT 665

Query: 611  LWKDVDRIIGLDQVAGMSETALP--GAFKTRK--GMFRTVGQLYKEQLAKLMATLRNTNP 666
            L+++          AG   T  P  G  + RK    F+TV QL+KE L KLM  LR T P
Sbjct: 666  LYENY---------AGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQP 716

Query: 667  NFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTP 726
            +FVRCI+PN  K  G +D  LVL QLRCNGVLEGIRICRQGFPNR+++ +FRQRY IL P
Sbjct: 717  HFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNP 776

Query: 727  NSIPKG-FMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIG 785
            ++IP   FMD ++A   ++ +L+LD   Y+ G +KVFF+AG+L  LEE RD ++  V+  
Sbjct: 777  SAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTL 836

Query: 786  FQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEE 845
             QA  RG L R  + +      A+  +Q N  A+  ++NW W +LF K+KPLL+ ++ EE
Sbjct: 837  LQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEE 896

Query: 846  EMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRAR 905
            E+ A   EL  +R    AAE +  E+E     +  EK  L  QLQAE +  A+AEE    
Sbjct: 897  ELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHL 956

Query: 906  LTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLE 965
            L   K +LE    +L  R+E+EEE    L A ++K++    EL++ +++ +    K + E
Sbjct: 957  LIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKE 1016

Query: 966  KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKH 1025
            K  TE K+K L EE   L++   +L KEKK L++   +   +L  EE++  +L K K + 
Sbjct: 1017 KQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRL 1076

Query: 1026 EAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEEL 1085
            E  + DLE  L +E+K R + E+ +RKLEGD     + +A+      +L+ +L KK+ EL
Sbjct: 1077 EQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSEL 1136

Query: 1086 QAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALK 1145
                 RVE+E        KKI+EL+++  EL+E+LE+ERA+R + EKQ+ +   ELE L 
Sbjct: 1137 SQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELS 1196

Query: 1146 TELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL 1205
              LE+   ++A Q+E   KRE E+  L++ LEE A  HEA +  +R+K ++   EL EQ+
Sbjct: 1197 ERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQV 1256

Query: 1206 EQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGE 1265
            +  +RV+  LEK K  L  E  +LA  V+ L + K  +E   +  E QL E ++K  E +
Sbjct: 1257 DSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQ 1316

Query: 1266 RVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKL 1325
            R   + + +  +LQ E   ++ LL + +   S+L++  +     L++ +  L+EE++ K 
Sbjct: 1317 RQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKS 1376

Query: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAE 1384
            +L+  ++ +  + +  REQ EEE EA+  L++ ++  +A+VA  + K E D++   E  E
Sbjct: 1377 ALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELE 1436

Query: 1385 EVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQK 1444
            E K+KL   L+   +  E   A    LEK K RLQ E +D+ ++L+    +A  L+KKQ+
Sbjct: 1437 EAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQR 1496

Query: 1445 KFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRT 1504
              ++ L E +    +   E + A+ E+R   T+   L    EEA+E    L+R NK  + 
Sbjct: 1497 HLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQE 1556

Query: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQA 1564
            E+ DL       GKS+ ELEK+K+ALE +  E++  LEE E  L+  E   LR+++ L  
Sbjct: 1557 EISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQ 1616

Query: 1565 MKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEA 1624
            +KA+ +R L  +DE+    ++   R V  ++A L+ E + R+ A+  +KK+E DL DLE 
Sbjct: 1617 VKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLEL 1676

Query: 1625 HIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQ 1684
             +  A +   EA    R +QAQ+K+     D+ +    E+  QA+  E++   + AE+ +
Sbjct: 1677 QLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEE 1736

Query: 1685 LQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGN 1744
            L+  L   ER++R A+QE  E  + +     +    L +K++LEA +AQL  E+EE    
Sbjct: 1737 LRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQE 1796

Query: 1745 TELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSK 1804
                 ++ KKA      +  +L  E+  +   E  ++ LE+  +EL+ +L+E E      
Sbjct: 1797 RREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRG 1856

Query: 1805 YKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQ 1864
             K  +  LEAK+ +LE +LD E K+   A K VR+ E+++K++  Q +++R+N  + +D 
Sbjct: 1857 GKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDL 1916

Query: 1865 ADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
             DK  +++K  KRQ EEAE++A    A  RK Q EL+DA E AD    + + L+ + R
Sbjct: 1917 VDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTR 1974



 Score =  240 bits (612), Expect = 1e-62
 Identities = 222/938 (23%), Positives = 444/938 (47%), Gaps = 69/938 (7%)

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAEL 1067
            L    +  + LA L+    A +  L   L   E +RQELE+T   +  +  DL+ Q+   
Sbjct: 888  LLRSAQAEEELAALR----AELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAE 943

Query: 1068 QAQIAEL----------KMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQ 1117
            Q  +A+           K+QL  K +EL   L   +EE    ++A ++ R+LE + +EL+
Sbjct: 944  QDNLADAEERCHLLIKSKVQLEGKVKELSERLE--DEEEVNADLAARR-RKLEDECTELK 1000

Query: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE 1177
            +D++  + +  KAEK+K       +A + ++++  +  AA  E  ++  +E    KK L+
Sbjct: 1001 KDIDDLKLTLAKAEKEK-------QATENKVKNLTEEMAALDESVARLTKE----KKALQ 1049

Query: 1178 EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLL 1237
            E               H QA+ +L  + +   RV A L KAK  LE +  +L   ++   
Sbjct: 1050 EA--------------HQQALGDLQAEED---RVSA-LTKAKLRLEQQVEDLECSLEQEK 1091

Query: 1238 QGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSS 1297
            + + D+E  ++K+E  L+  Q    +  + + +L +K+ K   EL  ++  +       +
Sbjct: 1092 KLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGA 1151

Query: 1298 KLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK 1357
            ++ K    L+++ ++ +E L+ E   +  +  +  +   E     E+LEE   A     +
Sbjct: 1152 QMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQRE 1211

Query: 1358 QIATLHAQVADMKKKMEDSVGCLE-TAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKT 1416
                  A++  +++++E++    E T   ++RK  +    L ++ +       KLEK K+
Sbjct: 1212 GCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKS 1271

Query: 1417 RLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKET 1476
             L+ E+DDL  +++   ++  + EK  + ++  L+E K    +   +   A  +    +T
Sbjct: 1272 ELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQT 1331

Query: 1477 KALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEE 1536
            ++  L+R LEE     ++L R        +E+L    ++  K+   L  + +AL    + 
Sbjct: 1332 ESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDL 1391

Query: 1537 MKTQLEELEDELQATEDAKL-RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME 1595
            ++ Q EE E E QA     L +    +   ++++E D   R E+ EE KK+L  +++E E
Sbjct: 1392 LREQHEE-EAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAE 1450

Query: 1596 AELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELD 1655
              +E    + S    A+ +L+ + +D+   ++ A        K+ R L+       R L+
Sbjct: 1451 EGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLE-------RALE 1503

Query: 1656 DTRASREEILAQAKENEKKLKSMEAEMIQL----QEELAAAERAKRQAQQERDELAD--E 1709
            + R   EE+  + +  +++ + +  E+ +L    +E L A E  KR+ +  ++E++D  +
Sbjct: 1504 ERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTD 1563

Query: 1710 IANSSGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768
              + SGK    LE+ K+ LE   ++++  LEE +G  EL   +  +  L++ Q+  ++  
Sbjct: 1564 QVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEV-- 1621

Query: 1769 ERSHAQKNE---NARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDN 1825
            +R  A+K+E   N R+  +R  + L+  L + E   +++       +E  +  LE QL +
Sbjct: 1622 DRKLAEKDEECANLRRNHQRAVESLQASL-DAETRARNEALRLKKKMEGDLNDLELQLGH 1680

Query: 1826 ETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEE 1885
             T++   A    R  + +LK+     D+E+R A +  +QA     R   L  +LEE    
Sbjct: 1681 ATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAA 1740

Query: 1886 AQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
             ++   SRR  ++EL +ATE  + ++ + + L N+ ++
Sbjct: 1741 LEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKK 1778



 Score =  201 bits (510), Expect = 8e-51
 Identities = 231/1043 (22%), Positives = 458/1043 (43%), Gaps = 123/1043 (11%)

Query: 735  DGKQACVLMIKA-LELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGY 793
            D ++ C L+IK+ ++L+  +  + + ++     V A L   R  K+ D     +      
Sbjct: 949  DAEERCHLLIKSKVQLEGKVKELSE-RLEDEEEVNADLAARRR-KLEDECTELKKDIDDL 1006

Query: 794  LARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEE--EMMAKE 851
                A A++++Q T  KV  +N    +   +    RL TK K  LQ + Q+   ++ A+E
Sbjct: 1007 KLTLAKAEKEKQATENKV--KNLTEEMAALDESVARL-TKEKKALQEAHQQALGDLQAEE 1063

Query: 852  EELVKVREKQLAAENRLTEMET-------LQSQLMAEKLQLQEQLQAETELCAEAEELRA 904
            + +  + + +L  E ++ ++E        L+      K +L+  L+   E  A+A + + 
Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQ 1123

Query: 905  RLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964
            +L  K ++ +     L  RVE+E+     +Q + K++Q   +ELEE+LE E +AR +++ 
Sbjct: 1124 QLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEK 1183

Query: 965  EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS----KSLAK 1020
            ++     +L++L E    LE+     A +++    R AE      E EE +     ++A 
Sbjct: 1184 QRAEAARELEELSER---LEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAA 1240

Query: 1021 LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLS------------------- 1061
            L+ K      +L E++   ++ RQ+LEK + +L  +  DL+                   
Sbjct: 1241 LRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRT 1300

Query: 1062 --DQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQIS----- 1114
              DQ++E + ++ EL+ QLA    +      R++ E+ + +  L++   L SQ+S     
Sbjct: 1301 YEDQLSEAKIKVEELQRQLA----DASTQRGRLQTESGELSRLLEEKECLISQLSRGKAL 1356

Query: 1115 ------ELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQE 1168
                  EL+  LE E  +++      + L  + + L+ + E+  ++ A  Q L SK   E
Sbjct: 1357 AAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAE 1416

Query: 1169 VNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGE 1228
            V   +   E +A     +++E ++K +  ++E  E +E      ++LEKAK  L+ E  +
Sbjct: 1417 VAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESED 1476

Query: 1229 LANEVKVLLQGKGDSEHKRKKVEAQLQE-----------LQVKFNEGERVRTEL------ 1271
            +  E++         + K++ +E  L+E           L+    E   + TEL      
Sbjct: 1477 VTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHG 1536

Query: 1272 -----------ADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE- 1319
                         +   LQ E+ ++T  +S S     +L K   ALE +  + Q  L+E 
Sbjct: 1537 HEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEA 1596

Query: 1320 ------ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEA---KHNLEKQIATLHA------ 1364
                  E  + L +  +L QV+ E +  R+  E++EE    + N ++ + +L A      
Sbjct: 1597 EGALELEETKTLRIQLELSQVKAEVD--RKLAEKDEECANLRRNHQRAVESLQASLDAET 1654

Query: 1365 ----QVADMKKKMEDSVGCLET-----------AEEVKRKLQKDLEGLSQRHEEKVAAYD 1409
                +   +KKKME  +  LE            A+   R +Q  L+      +E+     
Sbjct: 1655 RARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAA 1714

Query: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 1469
            +L +    L++    L  +L+  R +    E+ ++  +Q L E          +      
Sbjct: 1715 ELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLN 1774

Query: 1470 EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSS-KDDVGKSVHELEKSKR 1528
            + ++ E     L+  +EEA +++ E E   K+  T+   +    K +   S H LE+ K+
Sbjct: 1775 QKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKK 1833

Query: 1529 ALEQQVEEMKTQLEELEDE-LQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQL 1587
             LEQ V E++ +LEE E   L+  +    +LE  ++ ++A+ + + +   E  +  +K  
Sbjct: 1834 TLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKH- 1892

Query: 1588 VRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQM 1647
             R+V+E+  + E++RK  +       KL+  +K  +   + A +  +  + + RK Q ++
Sbjct: 1893 ERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHEL 1952

Query: 1648 KDCMRELDDTRASREEILAQAKE 1670
             D     D       ++ A+ ++
Sbjct: 1953 DDAEERADMAETQANKLRARTRD 1975



 Score =  152 bits (384), Expect = 3e-36
 Identities = 151/709 (21%), Positives = 314/709 (44%), Gaps = 74/709 (10%)

Query: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
            E E   L  E++ L      +E KR+    +L+E  V   +      E  D   +LQ E 
Sbjct: 895  EEELAALRAELRGLRGALAAAEAKRQ----ELEETHVSITQ------EKNDLALQLQAEQ 944

Query: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
            DN    L+ ++ +   L K    LE ++++  E L++E      L+ + +++EDE    +
Sbjct: 945  DN----LADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELK 1000

Query: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKM---EDSVGCLETAEEVKRKLQKDLEGLSQ 1399
            + +++ +      EK+      +V ++ ++M   ++SV  L   ++  ++  +   G  Q
Sbjct: 1001 KDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQ 1060

Query: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAK 1459
              E++V+A   L K K RL+Q+++DL   L+ +++   + E+ ++K +  L   +   A 
Sbjct: 1061 AEEDRVSA---LTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVAD 1117

Query: 1460 YAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519
             A+++ + E + ++K+++   L+  +E+     A++++  K+ +   E+L    +    +
Sbjct: 1118 AAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAA 1177

Query: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
               +EK +    +++EE+  +LEE         +   + E  L  ++ + E      +  
Sbjct: 1178 RARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEAT 1237

Query: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639
                +++      E+  +++  ++ R      + +L M++ DL A++++  + +  A K 
Sbjct: 1238 VAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKL 1297

Query: 1640 LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE----LAAAERA 1695
             R  + Q+ +   ++++ +      LA A     +L++   E+ +L EE    ++   R 
Sbjct: 1298 CRTYEDQLSEAKIKVEELQRQ----LADASTQRGRLQTESGELSRLLEEKECLISQLSRG 1353

Query: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
            K  A Q  +EL  ++   S   +      + L      L E+ EEE      +   L KA
Sbjct: 1354 KALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKA 1413

Query: 1756 NLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK 1815
            N ++ Q  +    E    Q+ E    +LE   K+L ++LQE E  V+        A  AK
Sbjct: 1414 NAEVAQWRS--KYEADAIQRTE----ELEEAKKKLALRLQEAEEGVE--------AANAK 1459

Query: 1816 IAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQL 1875
             + LE              K   R + + +DV L+++           +A  A+  L + 
Sbjct: 1460 CSSLE--------------KAKLRLQTESEDVTLELE-----------RATSAAAALDKK 1494

Query: 1876 KRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRG 1924
            +R LE A EE       RR+ + E++   E A   +R + +   +LR G
Sbjct: 1495 QRHLERALEE-------RRRQEEEMQRELEAAQRESRGLGTELFRLRHG 1536



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 69/279 (24%), Positives = 138/279 (49%), Gaps = 51/279 (18%)

Query: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQ-------QERDELA-------DEI 1710
            L ++ + E++L ++ AE+  L+  LAAAE  +++ +       QE+++LA       D +
Sbjct: 888  LLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNL 947

Query: 1711 ANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
            A++  +  L ++ K +LE ++ +L E LE+E+                  ++N DL   R
Sbjct: 948  ADAEERCHLLIKSKVQLEGKVKELSERLEDEE------------------EVNADLAARR 989

Query: 1771 SHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKER 1830
               +K E+   +L++   +LK+ L + E   K   +  +  L  ++A L+E +   TKE+
Sbjct: 990  ---RKLEDECTELKKDIDDLKLTLAKAEKE-KQATENKVKNLTEEMAALDESVARLTKEK 1045

Query: 1831 QAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQR-- 1888
            +A  +     ++ L D  LQ +++R +A        KA  RL+Q    LE + E+ ++  
Sbjct: 1046 KALQEA---HQQALGD--LQAEEDRVSA------LTKAKLRLEQQVEDLECSLEQEKKLR 1094

Query: 1889 --ANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
                 ++RKL+ +L+   E+     ++   L+ KL++ D
Sbjct: 1095 MDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKD 1133


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 1236 bits (3197), Expect = 0.0
 Identities = 711/1904 (37%), Positives = 1110/1904 (58%), Gaps = 27/1904 (1%)

Query: 29   KKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAE 88
            KK  W+P  ++ +  A +K    +  ++    +G+ + + +D IQ+MNPP+F  +EDMA 
Sbjct: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110

Query: 89   LTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPP 148
            LT LNEASVLH LK RY   +IYTYSGLFCV INPYK LP+Y +E++  YKGK+R E PP
Sbjct: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170

Query: 149  HIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELE 208
            HI+A+ + A++ M+ +RE+QSIL TGESGAGKT N+K +IQY A +A+  +S+K QG LE
Sbjct: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGALE 230

Query: 209  RQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQA 268
             Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ YLLEKSR I Q 
Sbjct: 231  DQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQ 290

Query: 269  KEERTFHIFYYLLSGAGEHLKTDLLLEPYN--KYRFLSNGHVTIPGQQDKDMFQETMEAM 326
              ER +HIFY +LSG  E    DLLL   N   + F S G VT+    D +    T +AM
Sbjct: 291  AGERNYHIFYQILSGQKE--LHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATEQAM 348

Query: 327  RIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFT 386
             I+G   +E+ G  ++   ++  GN+ FK++   +Q        A K + L+GIN ++  
Sbjct: 349  DILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSSELV 408

Query: 387  RGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALD-KTKRQGA 445
            + ++ PRIKVG +YV + QT EQ   A+ AL+K+ YERMF+WLV RIN+ALD K  RQ  
Sbjct: 409  KCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSRQ-- 466

Query: 446  SFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFG 505
             FIGILDI GFEI + NS EQLCIN+TNEKLQQ FN  MF+LEQEEY++E IEW  I FG
Sbjct: 467  FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFG 526

Query: 506  LDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQE---QGTHPKFQKPKQL 562
            LDLQ CIDLIEKP    GIL++L+EEC FPKATD +F  K+      +  H +  KP + 
Sbjct: 527  LDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKK 583

Query: 563  KDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLD 622
            K +A F ++HYAG V Y    WL KN D LN+ +  +  +SS++ ++ L+++        
Sbjct: 584  KFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENY------- 636

Query: 623  QVAGMSETALPGAFKTRK--GMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKA 680
                 +++A+P   K RK    F+TV  L+KE L KLM  L++T P+FVRCI PN  K  
Sbjct: 637  ---MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIP 693

Query: 681  GKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDGKQA 739
            G LDP+LVL QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL P + PK  F+  ++A
Sbjct: 694  GILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKA 753

Query: 740  CVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAF 799
               ++ +LE+D   YR G +KVFF+AG L  LE  RD +++ V   FQA  +G L R  F
Sbjct: 754  AEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKF 813

Query: 800  AKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVRE 859
             K  ++  A+ ++Q N  A++ ++NW W RLF K+KPL++ S   EE+   +EE  ++++
Sbjct: 814  QKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQK 873

Query: 860  KQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHD 919
                +E +  E++  Q  L  EK  L  QLQAE E  A  EE    L   K +LE    +
Sbjct: 874  ALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKE 933

Query: 920  LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979
            L  RVEEEEE    L A  +K++    EL++++++ E+   K + EK TTE K+K L EE
Sbjct: 934  LSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEE 993

Query: 980  QIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE 1039
               L +   KL +  K++++   +   +L  EEEK  SL+K   K E  + +LE  L +E
Sbjct: 994  VEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQE 1053

Query: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099
             K R   E+   KLEG+     + +  L++    L  +L KKE EL    ++VE E    
Sbjct: 1054 RKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLV 1113

Query: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
                K ++EL++QI +L+E LE+ER +R K E+++ DL ++L  L   LE+   S+ AQ 
Sbjct: 1114 AQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQL 1173

Query: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
            E+  K+E +   L + +EE     E     ++++H+ ++ EL  Q+E  ++VK  LEK K
Sbjct: 1174 EITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDK 1233

Query: 1220 QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279
              L+ E  +L   V+ + + K ++E      E +L E   K ++  ++  +LA + TKL 
Sbjct: 1234 SDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLW 1293

Query: 1280 VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339
             E       L + ++  ++L+++ S    Q++D +  L++E + + +L+  L++ + + +
Sbjct: 1294 SESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCD 1353

Query: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSV-GCLETAEEVKRKLQKDLEGLS 1398
              REQ EEE+E K  L + ++ ++A++   + K E++V    E  E+ K++L   L+  +
Sbjct: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413

Query: 1399 QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISA 1458
            +      A    LE+ + +LQ EL D L DL   R +A  L++KQ +  + LA+ K    
Sbjct: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHE 1473

Query: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK 1518
            +     D ++ E +   T+ L L    EE++  +  L R NK  + E+ +L +   +  K
Sbjct: 1474 ESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTK 1533

Query: 1519 SVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDE 1578
            ++ E+EK K+ +E++  E++  LEE E  L+  E   L  ++ L   KA+ ER L  +DE
Sbjct: 1534 NLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDE 1593

Query: 1579 QSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIK 1638
            + E  +++    +  +++ L+ E K R      +KK+E DL ++E  +  AN+   EA K
Sbjct: 1594 EIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATK 1653

Query: 1639 QLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQ 1698
             L +LQ Q+KD   +LDD+     ++  Q    E++   +++E+  L+      ER +R 
Sbjct: 1654 SLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRL 1713

Query: 1699 AQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQ 1758
            +++E  E  + I     +    L +K++LEA +A++++E EE     +   ++ KKA ++
Sbjct: 1714 SEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIE 1773

Query: 1759 IDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQ 1818
               ++ +L  ++      E  R+ +E+   +L+ +L E E       +  I  LE+++ +
Sbjct: 1774 AANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRE 1833

Query: 1819 LEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQ 1878
            LE +L+ E +    A +  RR E+ +K++  Q +++++N  + + Q DK   +++  K+Q
Sbjct: 1834 LEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQ 1893

Query: 1879 LEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            +E AE +A +  +  +K Q EL +  E A+    +V+ LK K R
Sbjct: 1894 VEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937



 Score =  218 bits (555), Expect = 5e-56
 Identities = 215/973 (22%), Positives = 446/973 (45%), Gaps = 73/973 (7%)

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAEL 1067
            L +  E  + +A LK +       L++ L + E QR+EL+  +  L  +  DL  Q+   
Sbjct: 851  LVKSSEVGEEVAGLKEE----CAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAE 906

Query: 1068 QAQIAELKMQ---LAKKEEELQAALA----RVEEEAAQKNMALKKIRELESQISELQEDL 1120
            Q  +A ++ Q   L K + +L+A +     RVEEE    +    + R+LE +  EL++++
Sbjct: 907  QETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEI 966

Query: 1121 ESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA 1180
            +       K+EK+KR    +++ L  E+E  L+   ++    +K  QE +  ++TL++  
Sbjct: 967  DDLETMLVKSEKEKRTTEHKVKNLTEEVE-FLNEDISKLNRAAKVVQEAH--QQTLDDLH 1023

Query: 1181 KTHE--AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
               E  + + +   K  Q V+EL   LEQ ++ + N E+    LE         ++ L  
Sbjct: 1024 MEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLES 1083

Query: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298
             +     + +K E +L ++  K    + +  +L   V +LQ ++ ++   L    +  +K
Sbjct: 1084 SQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAK 1143

Query: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
            + ++ + L   L D  E L+E     L+   +L+  + ++  F++   + EEA  + E  
Sbjct: 1144 MERERADLTQDLADLNERLEEVGGSSLA---QLEITKKQETKFQKLHRDMEEATLHFETT 1200

Query: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL 1418
             A+L  + AD   ++E   G +E  ++VK+KL+KD                     K+ L
Sbjct: 1201 SASLKKRHADSLAELE---GQVENLQQVKQKLEKD---------------------KSDL 1236

Query: 1419 QQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478
            Q E+DDLL  ++   ++  N EK    +++ L E      K  +  +   A+  +  +++
Sbjct: 1237 QLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSES 1296

Query: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538
                R LEE      +L R    F  ++EDL    +   KS   L  + +  ++  + ++
Sbjct: 1297 GEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLR 1356

Query: 1539 TQLEELEDELQATEDAKL-RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE 1597
             Q EE E E++A     L ++   +   + ++E ++  R E  E+ KK+L  +++E    
Sbjct: 1357 EQYEE-EQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEA 1415

Query: 1598 LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657
            +     + +    AR +L+++L D    +    K R  A +    L  +     + L D 
Sbjct: 1416 MGVANARNASLERARHQLQLELGDA---LSDLGKVRSAAAR----LDQKQLQSGKALADW 1468

Query: 1658 RASREEILAQAKENEKKLKSMEAEMIQL----QEELAAAERAKRQAQQERDELADEIANS 1713
            +   EE  A    ++K+++++  E+++L    +E +   E  +R+ +  ++E+++ + N 
Sbjct: 1469 KQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISN-LTNQ 1527

Query: 1714 SGKGALALEE----KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE 1769
              +G   L E    K+ +E    +++  LEE +G  E   +  K  + Q++ +     LE
Sbjct: 1528 VREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALE--RNESKILHFQLELLEAKAELE 1585

Query: 1770 RSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITA------LEAKIAQLEEQL 1823
            R  ++K+E    ++E   ++ +  +  ++ ++ S+ K+ I        +E  + ++E QL
Sbjct: 1586 RKLSEKDE----EIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQL 1641

Query: 1824 DNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAE 1883
                ++   A K + + + ++KD+ +Q+DD  +     K+Q   A  R   L+ +LE+  
Sbjct: 1642 SCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLR 1701

Query: 1884 EEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGS 1943
               ++    RR  + EL +ATE  +    + +SL ++ ++ +      ++ A +   +  
Sbjct: 1702 SLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQ 1761

Query: 1944 DEEVDGKADGAEA 1956
            + E   K    EA
Sbjct: 1762 NAEEKAKKAAIEA 1774



 Score =  189 bits (481), Expect = 2e-47
 Identities = 191/982 (19%), Positives = 433/982 (44%), Gaps = 118/982 (12%)

Query: 800  AKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQE-EEMMAKEEELVKVR 858
            ++++++ T  KV  +N    ++  N    +L    K + +  +Q  +++  +EE+L  + 
Sbjct: 976  SEKEKRTTEHKV--KNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLS 1033

Query: 859  EKQLAAENRLTEMETLQSQLMAEKL-------QLQEQLQAETELCAEAEELRARLTAKKQ 911
            +  L  E ++ E+E    Q    ++       +L+  L+   E     E  +  L  + +
Sbjct: 1034 KANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELR 1093

Query: 912  ELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEA 971
            + E     + ++VE E+     LQ   K++Q  I++L+E+LE E + R K++ E+     
Sbjct: 1094 KKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQ 1153

Query: 972  KLKKLEE--EQI---------ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK 1020
             L  L E  E++         I + Q  K  K  + +E+    F T          + A 
Sbjct: 1154 DLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFET----------TSAS 1203

Query: 1021 LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 1080
            LK +H   + +LE ++   ++ +Q+LEK +  L+ +  DL  ++ ++    A  +     
Sbjct: 1204 LKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTL 1263

Query: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
             EE L  A A++++     N    +  +L S+  E    LE + A  N+  ++K +   +
Sbjct: 1264 YEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQ 1323

Query: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE----AKTHE------AQIQEM 1190
            +E L+ +LE    S +A      K +++ ++L++  EEE    A+ H       A++ + 
Sbjct: 1324 IEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQW 1383

Query: 1191 RQKHSQAVEELAEQLEQTKRV------------------KANLEKAKQTLENERGELANE 1232
            R K+   V +  E LE  K+                    A+LE+A+  L+ E G+  ++
Sbjct: 1384 RMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSD 1443

Query: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQS 1292
            +  +       + K+ +    L + + K  E + +      +V  L  EL  +     +S
Sbjct: 1444 LGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEES 1503

Query: 1293 DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEE--- 1349
                  L ++   L+ ++ +    ++E  +    +    K +E+EK   +  LEE E   
Sbjct: 1504 IVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGAL 1563

Query: 1350 ---------------EAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDL 1394
                           EAK  LE++++    ++ + ++K + ++  L+++ + + K + ++
Sbjct: 1564 ERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEV 1623

Query: 1395 EGLSQRHEEKV---------AAYDKLEKTKT--RLQQELDDLLVDLDHQRQSACNLEKK- 1442
              L ++ EE +         A     E TK+  +LQ ++ DL + LD   Q   +L+++ 
Sbjct: 1624 TRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQV 1683

Query: 1443 ----------QKKFDQLLA-EEKTISAKYAEERDRAEAEAR-------------EKETKA 1478
                      Q + + L + +E+T   +   E +  EA  R             +K+   
Sbjct: 1684 AVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLE 1743

Query: 1479 LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK---SVHELEKSKRALEQQVE 1535
              +AR  +EA E   E +   ++ +    +  +  +++ K   ++  LE+++  +EQ + 
Sbjct: 1744 ADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTIT 1803

Query: 1536 EMKTQLEELED-ELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREM 1594
            +++ +L E E   L  +     +LE  ++ ++ + E +++ R  +++   ++L R ++E+
Sbjct: 1804 DLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIR-RSAEAQRGARRLERCIKEL 1862

Query: 1595 EAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL 1654
              + E+++K  S       KL++ +++ +  ++ A    ++ + + +K Q ++ +     
Sbjct: 1863 TYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERA 1922

Query: 1655 DDTRASREEILAQAKENEKKLK 1676
            +   +   ++  +A+E  KK++
Sbjct: 1923 EVAESQVNKLKIKAREFGKKVQ 1944



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 39/178 (21%), Positives = 72/178 (40%), Gaps = 33/178 (18%)

Query: 835  KPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEM-----ETLQSQLMAEKLQLQEQL 889
            K  ++ +   EE+  K++ +  +   +   E  +T++     E  Q  LM  + Q+Q+  
Sbjct: 1769 KAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLE 1828

Query: 890  QAETELCAEAE-ELRARLTAKK--QELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ 946
                EL  E E E+R    A++  + LE    +L  + EE+++    +Q +  K+Q  +Q
Sbjct: 1829 SRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQ 1888

Query: 947  -------------------------ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979
                                     EL E  E  E A  ++   K+      KK++EE
Sbjct: 1889 NYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQEE 1946


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  590 bits (1521), Expect = e-168
 Identities = 453/1489 (30%), Positives = 747/1489 (50%), Gaps = 163/1489 (10%)

Query: 32   VWVPSDKSGFEPASLKEEV--GEEAIVELVENGKKVKVNKDDIQK-----MNPPKFSKVE 84
            VW+P  +  ++ A L ++   G++ ++  +E GK ++ + D   K      NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 85   DMAELTCLNEASVLHNLKERYY-SGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKR 143
            D+  L+ L+E +VLHNL+ R+  S LIYTY G+  V INPY+ LPIY E+I+  Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 144  HEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD 203
             +M PHI+A+ + AY+ M +D  +QSI+ +GESGAGKT + K  ++Y A V+ S      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS----AS 188

Query: 204  QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSR 263
            +  +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD    I+GAN+ TYLLEKSR
Sbjct: 189  EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248

Query: 264  AIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFL-SNGHVTIPGQQDKDMFQET 322
             + QA+EER +HIFY L + A       L L   + + +    G   I G  D      T
Sbjct: 249  VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHT 308

Query: 323  MEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKV-SHLLGIN 381
             +A  ++GI E  QMG+ R+++G+L LGN+ F   R+ D  ++P       +   L+G++
Sbjct: 309  RQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLMGVD 367

Query: 382  VTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTK 441
              +    +   ++    +   K  +K QA  A +ALAK  Y ++F W+V  +N+AL    
Sbjct: 368  YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAV 427

Query: 442  RQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 501
            +Q  SFIG+LDI GFE F++NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I W  
Sbjct: 428  KQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTL 486

Query: 502  IDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTH----PKFQ 557
            IDF  D QPCI+LIE      GIL LLDEEC  PK TD ++ +K+     TH      F+
Sbjct: 487  IDF-YDNQPCINLIESKL---GILDLLDEECKMPKGTDDTWAQKL---YNTHLNKCALFE 539

Query: 558  KPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDR 617
            KP+ L +KA F I H+A KV+Y+ + +L KN D + +    +L  S  K + EL++D ++
Sbjct: 540  KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597

Query: 618  IIGLDQVAGMSETALPGA----FKTRKGMF-----RTVGQLYKEQLAKLMATLRNTNPNF 668
             I          T L        K R G       +TVG  ++  L  LM TL  T P++
Sbjct: 598  AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657

Query: 669  VRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNS 728
            VRCI PN  K     D    + QLR  GVLE IRI   GFP+R  +QEF  RY +L    
Sbjct: 658  VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQK 717

Query: 729  IPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQA 788
                  D KQ C  +++ L LD + Y+ G++K+FFRAG +A+LE+ R  K+    I  Q 
Sbjct: 718  --DVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775

Query: 789  CCRGYLARKAFAKRQQQLTAM-------------KVLQRNCAAYLKLRNWQWWRLFTKVK 835
              RG+L RK + + ++    M             K L+R  AA +  + W+ + +  + K
Sbjct: 776  TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYK 835

Query: 836  ------PLLQ------VSRQEEEMMAKEEELVKVREK--------------------QLA 863
                   +LQ      ++R     + +E + V ++++                    Q  
Sbjct: 836  IRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCC 895

Query: 864  AENRLTEMETLQSQLMAEKLQLQEQL---------QAETELCAEAEELRARLTAKKQELE 914
                + + E  + ++ A  ++  ++L         Q + ++  + ++ +  L  K   LE
Sbjct: 896  FRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKC-LVEKLTNLE 954

Query: 915  EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEK--VTTEAK 972
             I +    ++  + ER Q  + E K     +  L+E++ +     ++ + EK  +   A 
Sbjct: 955  GIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHAD 1014

Query: 973  LKKLEEEQII--LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEK-----SKSLAKLKNKH 1025
              K E EQ++  L+++N  L +EK+ L  RI +    +TE  EK     +K L    N  
Sbjct: 1015 RYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDE 1074

Query: 1026 EAMITDLEERLRREEKQRQELEKTRRKL---------EGDSTDLSDQIAEL-QAQIAELK 1075
                 +L     R E++  +L++    +           DST  S++   +  ++IAE+ 
Sbjct: 1075 RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEM- 1133

Query: 1076 MQLAKKEEELQAALARVEEEAAQKNMAL-----KKIRELESQISELQEDLE--SERASRN 1128
                   E++ +      E+    +M+L     K++ ELE +   +Q++L+   E+  R+
Sbjct: 1134 -------EDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRS 1186

Query: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS---KREQEVNILKKTLEEEAKTHEA 1185
            KA++++R    ++   + E E     +  +QEL S   K + E+N L+K L E++     
Sbjct: 1187 KAKEEER---PQIRGAELEYE-----SLKRQELESENKKLKNELNELRKALSEKS----- 1233

Query: 1186 QIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEH 1245
               E+    + A   L EQL     V   L+  K+ +   R +L ++ K  +Q K D ++
Sbjct: 1234 -APEVTAPGAPAYRVLMEQLTS---VSEELDVRKEEVLILRSQLVSQ-KEAIQPK-DDKN 1287

Query: 1246 KRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSA 1305
                    L+++Q   ++GE  +  +  K T   +E   +       ++++  L  +  +
Sbjct: 1288 TMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLE-SQLQSQKRSHENEAEALRGEIQS 1346

Query: 1306 LESQLQDTQELLQE------ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQI 1359
            L+ +    Q+LL +      E R + SL  ++ ++ +E     EQLE++++    L+KQ+
Sbjct: 1347 LKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQL 1406

Query: 1360 ATLHAQVADMKKKMEDSVGCLETAEEVKR-----KLQKDLEGLSQRHEE 1403
                 ++ +++    +++   +  +E  R     + +KD +G+ +  +E
Sbjct: 1407 KVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKE 1455



 Score = 81.6 bits (200), Expect = 7e-15
 Identities = 116/550 (21%), Positives = 234/550 (42%), Gaps = 66/550 (12%)

Query: 1306 LESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK-QIATLHA 1364
            +E+++   Q  + E+N+    L  KL  +E   NS      E E+ + +LE+ Q++   A
Sbjct: 925  MENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS------ETEKLRSDLERLQLSEEEA 978

Query: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDD 1424
            +VA          G + + +E   KL+KDLE    R E+K      +E+   R +QE + 
Sbjct: 979  KVA---------TGRVLSLQEEIAKLRKDLE--QTRSEKKC-----IEEHADRYKQETEQ 1022

Query: 1425 LLVDLDHQRQSACNLEKKQKKFDQLLAEE-----KTISAKYAEERDRAEAEAREKETKAL 1479
            L+ +L  +      L+++++  +  + ++     +T+  K  EE  + E +  ++  +  
Sbjct: 1023 LVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQ 1079

Query: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
            +L        E+  +L    K+  T M  +         S H   +S+     ++ EM+ 
Sbjct: 1080 NLLNEFSRLEERYDDL----KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135

Query: 1540 QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1599
                 E+  +      + L + LQ    + E++ Q   ++ + K++Q++R   + E   +
Sbjct: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195

Query: 1600 DERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRA 1659
                +       R++LE + K L+  ++   K   E  K   ++ A      R L +   
Sbjct: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSE--KSAPEVTAPGAPAYRVLMEQLT 1253

Query: 1660 SREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGAL 1719
            S  E L   KE          E++ L+ +L     ++++A Q +D+      N+     +
Sbjct: 1254 SVSEELDVRKE----------EVLILRSQLV----SQKEAIQPKDD-----KNTMTDSTI 1294

Query: 1720 ALEEKRRL--EARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNE 1777
             LE+ +++  +  IAQ    L+E      L+  +L+      +     L  E    ++  
Sbjct: 1295 LLEDVQKMKDKGEIAQAYIGLKE---TNRLLESQLQSQKRSHENEAEALRGEIQSLKEEN 1351

Query: 1778 NARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQV 1837
            N +QQL  QN +L       E  +++  +  IT L  +   L EQL+ + K  +   KQ+
Sbjct: 1352 NRQQQLLAQNLQL-----PPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQL 1406

Query: 1838 RRTEKKLKDV 1847
            +   KK+ ++
Sbjct: 1407 KVFAKKIGEL 1416



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 177/841 (21%), Positives = 352/841 (41%), Gaps = 108/841 (12%)

Query: 804  QQLTAMKVLQ--RNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQ 861
            QQL A  VL+  R  AA    R W +   F++ + L+   +Q++ +  +++    V EK 
Sbjct: 679  QQLRACGVLETIRISAAGFPSR-WTYQEFFSRYRVLM---KQKDVLSDRKQTCKNVLEKL 734

Query: 862  LAAENRLTEMETLQSQLMAEKLQLQEQLQAET--ELCAEAEE-LRARLTAKKQ-ELEEIC 917
            +  +++    +T +    A ++   E+L+A+     C   ++ +R  L  KK   + +  
Sbjct: 735  ILDKDKYQFGKT-KIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAA 793

Query: 918  HDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLE 977
              ++  V   + RC      + K    IQ+           R++ ++ +  T      L 
Sbjct: 794  ITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYV----VRRRYKIRRAATIVLQSYLR 849

Query: 978  EEQIILEDQNCKLAKEKK--LLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLE-E 1034
                +  ++  K+ +E K  +++ R+  +    T  +    ++  L+     M+   E +
Sbjct: 850  G--FLARNRYRKILREHKAVIIQKRVRGWLAR-THYKRSMHAIIYLQCCFRRMMAKRELK 906

Query: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAE-------LQAQIAELKMQLAKKEEELQA 1087
            +L+ E +  +  +K    +E     L  ++ E       L  ++  L+     + E+L++
Sbjct: 907  KLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRS 966

Query: 1088 ALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTE 1147
             L R++    +  +A  ++  L+ +I++L++DLE  R+       +K+ + E  +  K E
Sbjct: 967  DLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRS-------EKKCIEEHADRYKQE 1019

Query: 1148 LEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEA--QIQEMRQKHSQAVEELAEQL 1205
             E          +L S  ++E  +LK+  E+EA  H    Q +EM +   + + E  +QL
Sbjct: 1020 TE----------QLVSNLKEENTLLKQ--EKEALNHRIVQQAKEMTETMEKKLVEETKQL 1067

Query: 1206 E---QTKRVK-ANLEKAKQTLENERGELANEVKVLLQ------GKGDSEHKRKKVEAQLQ 1255
            E     +R++  NL      LE    +L  E+ +++        + DS H   + E  + 
Sbjct: 1068 ELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE-YIF 1126

Query: 1256 ELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQE 1315
              ++   E    RTE   + ++ +V LD    L         KL K  + LE + Q  Q+
Sbjct: 1127 SSEIAEMEDIPSRTE---EPSEKKVPLDMSLFL---------KLQKRVTELEQEKQVMQD 1174

Query: 1316 LLQEENRQKLSLSTKLKQVEDEKNSFR-EQLEEEEEAKHNLEKQIATLHAQVADMKKKME 1374
             L  +  Q L    K    E+E+   R  +LE E   +  LE +   L  ++ +++K + 
Sbjct: 1175 ELDRKEEQVLRSKAK----EEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALS 1230

Query: 1375 DSVGCLETAEEVK--RKLQKDLEGLSQ----RHEEKVAAYDKLEKTKTRLQQELDD---- 1424
            +      TA      R L + L  +S+    R EE +    +L   K  +Q + D     
Sbjct: 1231 EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMT 1290

Query: 1425 ----LLVDLDHQR------QSACNLEKKQKKFDQLLAEEKTISAKYAEE-RDRAEAEARE 1473
                LL D+   +      Q+   L++  +  +  L  +K      AE  R   ++   E
Sbjct: 1291 DSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEE 1350

Query: 1474 KETKALSLARALEEAMEQKAE--LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALE 1531
               +   LA+ L+   E + E  L+    +   E  DLM   +   K+V +L+K  +   
Sbjct: 1351 NNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFA 1410

Query: 1532 QQVEEMKT-QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
            +++ E++  Q+E +       E  +    VN+       E+D QG  E  +E +++LV+ 
Sbjct: 1411 KKIGELEVGQMENISPGQIIDEPIR---PVNIPRK----EKDFQGMLEYKKEDEQKLVKN 1463

Query: 1591 V 1591
            +
Sbjct: 1464 L 1464



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 21/210 (10%)

Query: 1650 CMRELDDTRASRE-EILAQAKENEKKLK-SMEAEMIQLQEELAAAERAKRQAQQERDE-- 1705
            C R +   R  ++ +I A++ E  KKL   ME +++QLQ ++          +Q +D   
Sbjct: 895  CFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVD---------EQNKDYKC 945

Query: 1706 LADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTD 1765
            L +++ N  G      E+ R    R+   EEE +   G    + + + K    ++Q  ++
Sbjct: 946  LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005

Query: 1766 LNLERSHAQKNENARQQ----LERQNKELKVKLQEMEGTVKSKYKASITALEAKIA---- 1817
                  HA + +   +Q    L+ +N  LK + + +   +  + K     +E K+     
Sbjct: 1006 KKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065

Query: 1818 QLEEQLDNETKERQAACKQVRRTEKKLKDV 1847
            QLE  L++E    Q    +  R E++  D+
Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDL 1095



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 30/164 (18%), Positives = 78/164 (47%), Gaps = 21/164 (12%)

Query: 1768 LERSHAQKNENA---------RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQ 1818
            L R+H +++ +A         R   +R+ K+LK++ + +E     +YK     +E KI Q
Sbjct: 877  LARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVE-----RYKKLHIGMENKIMQ 931

Query: 1819 LEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQ 1878
            L+ ++D + K+ +   +++   E        ++  +    +  +++A  A+ R+  L+ +
Sbjct: 932  LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEE 991

Query: 1879 LEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            + +  ++ ++  + ++ ++       E AD   +E   L + L+
Sbjct: 992  IAKLRKDLEQTRSEKKCIE-------EHADRYKQETEQLVSNLK 1028



 Score = 37.4 bits (85), Expect = 0.15
 Identities = 32/160 (20%), Positives = 73/160 (45%), Gaps = 10/160 (6%)

Query: 1752 LKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV---KLQEMEGTVKSKYKAS 1808
            LKK  ++   +     L      K    +++++ QNK+ K    KL  +EG   S+ +  
Sbjct: 905  LKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKL 964

Query: 1809 ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKA 1868
             + LE ++   EE+    T    +  +++ +  K L+    +      +A++YK + ++ 
Sbjct: 965  RSDLE-RLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQL 1023

Query: 1869 STRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETAD 1908
             + LK+    L++ +E      A   ++ ++ ++ TET +
Sbjct: 1024 VSNLKEENTLLKQEKE------ALNHRIVQQAKEMTETME 1057


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  588 bits (1517), Expect = e-167
 Identities = 436/1427 (30%), Positives = 721/1427 (50%), Gaps = 155/1427 (10%)

Query: 32   VWVPSDKSGFEPASLKEE--VGEEAIVELVENGKKV--KVNKDDIQKM-NPPKFSKVEDM 86
            VW+P  +  ++ A + ++  VG++ +  L+E+G ++   VN + +  + NP       D+
Sbjct: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72

Query: 87   AELTCLNEASVLHNLKERYY-SGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHE 145
              L+ L+E +VLHNL+ R+  S LIYTYSG+  V +NPYK LPIY + I+  Y G+   +
Sbjct: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132

Query: 146  MPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQG 205
            M PHI+A+ + AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S  +     
Sbjct: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN----A 188

Query: 206  ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAI 265
             +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD    I+GAN+ TYLLEKSR +
Sbjct: 189  HVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVV 248

Query: 266  RQAKEERTFHIFYYLLSGAGE----HLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQE 321
             Q++ ER +HIFY L + A +    HLK     E +N  R    G+  I G  D+    E
Sbjct: 249  FQSENERNYHIFYQLCASAQQSEFKHLKLG-SAEEFNYTRM--GGNTVIEGVNDRAEMVE 305

Query: 322  TMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGIN 381
            T +   ++G  E+ QM + ++++ +L LGN+      N   +   D++  +    LLG+ 
Sbjct: 306  TQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLGLE 365

Query: 382  VTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTK 441
                 + +   +I    + V K  T+ QA  A +ALAK  Y  +F ++V RIN+AL  + 
Sbjct: 366  SGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQFSG 425

Query: 442  RQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 501
            +Q  +FIG+LDI GFE FD+NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I W  
Sbjct: 426  KQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWTL 484

Query: 502  IDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQE-QGTHPKFQKPK 560
            IDF  D QP IDLIE      GIL LLDEEC  P  TD+++++K+       +P F+KP+
Sbjct: 485  IDF-YDNQPVIDLIE---AKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPR 540

Query: 561  QLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKD----VD 616
                   F I H+A KV+YK + +L KN D + D +  +L  S     +  +++      
Sbjct: 541  M--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPS 598

Query: 617  RIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNH 676
                +  V    +   P +    K    TVG  ++  L  LM TL  T P++VRCI PN 
Sbjct: 599  PFGSMITVKSAKQVIKPNS----KHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPND 654

Query: 677  EKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDG 736
            EK   + D   ++ QLR  GVLE IRI  Q +P+R  + EF  RY IL        F D 
Sbjct: 655  EKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSFSDK 713

Query: 737  KQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLAR 796
            K+ C +++  L  DSN Y+ G++K+FFRAG +A+LE+ R  K+    +  Q   RG+L R
Sbjct: 714  KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQR 773

Query: 797  KAFAKRQQ-----------QLTAMK--------------VLQRNCAAYLKLRNWQWWRLF 831
            K F + ++           Q T  K              ++Q++C  YL           
Sbjct: 774  KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYL----------- 822

Query: 832  TKVKPLLQVSRQEEEMMAKEEE--LVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQL 889
              V+ L Q+ R     M       L + R +++  E++   ++      +A +     + 
Sbjct: 823  --VRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARR-----RF 875

Query: 890  QAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949
            Q+          L  +LT + Q L++   D         E+   L A +    + IQ+LE
Sbjct: 876  QSIRRFV-----LNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLE 930

Query: 950  EQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT 1009
             +LE+  + R+         E K K+  +    +E++  KL K    LE +  +    L 
Sbjct: 931  AELEKAATHRRNY-------EEKGKRYRD---AVEEKLAKLQKHNSELETQKEQIQLKLQ 980

Query: 1010 EEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA 1069
            E+ E      +LK K + +   L + +++EE+QR  LEK+    E  + D   QI  L+ 
Sbjct: 981  EKTE------ELKEKMDNLTKQLFDDVQKEERQRMLLEKS---FELKTQDYEKQIQSLKE 1031

Query: 1070 QIAEL---KMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQ-EDLESERA 1125
            +I  L   KMQL    E        ++ E A+ +  +K I E E +I  LQ + ++ E+ 
Sbjct: 1032 EIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEK- 1090

Query: 1126 SRNKAEKQKRDLGEELEALKTELEDTLD-----STAAQQELRSKREQ-EVNILKKTLEEE 1179
                 + QKR++ E++  +  +L ++ D     S  + ++L    E  E+    + L++ 
Sbjct: 1091 ---HVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKA 1147

Query: 1180 AKTHEAQIQEMRQKHSQAVE-------ELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
             +  E+  Q  +  + + +E        L++++   +++        +++ +E   L +E
Sbjct: 1148 TRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSE 1207

Query: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQS 1292
              ++     D + +  ++E Q Q+L+++ NE          +  K++ +L+ ++  L +S
Sbjct: 1208 NMMI----PDFKQQISELEKQKQDLEIRLNE----------QAEKMKGKLEELSNQLHRS 1253

Query: 1293 DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAK 1352
              +     K   ALE+Q        +   ++K  L  K++++++  +  ++Q E E E K
Sbjct: 1254 QEEEGTQRK---ALEAQ-------NEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVK 1303

Query: 1353 HNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399
             N  ++ + L  +  D++++       L+  + V +KLQ  ++ LS+
Sbjct: 1304 CNFRQEASRLTLENRDLEEE-------LDMKDRVIKKLQDQVKTLSK 1343



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 150/654 (22%), Positives = 279/654 (42%), Gaps = 95/654 (14%)

Query: 784  IGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQ 843
            I  QA  RG+LAR+ + K  ++  A+ +LQ+   A+L  R +Q  R F     +L +   
Sbjct: 835  ITMQAYSRGFLARRRYRKMLEEHKAV-ILQKYARAWLARRRFQSIRRF-----VLNI--- 885

Query: 844  EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCA------ 897
              ++  + + L K  E Q    + L E  T  + L A  ++  ++L+AE E  A      
Sbjct: 886  --QLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNY 943

Query: 898  --EAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAE-KKKMQQNIQELEEQLEE 954
              + +  R  +  K  +L++   +LE + E+ + + Q    E K+KM    ++L + +++
Sbjct: 944  EEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQK 1003

Query: 955  EESARQKLQ----LEKVTTEAKLKKLEEEQIILEDQNCKL---AKEKKLLEDRIAEFTTN 1007
            EE  R  L+    L+    E +++ L+EE   L+D+  +L    + + +  D +      
Sbjct: 1004 EERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVAR 1063

Query: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQE--------------LEKTRRKL 1053
            L+++ +      K     +A   D+E+ ++ ++++ +E              +E  R +L
Sbjct: 1064 LSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRL 1123

Query: 1054 EGDSTDLSDQIAEL---------QAQIAELKMQLAKK--EEELQAALARVEEEAAQKNMA 1102
              +  +  ++  EL           ++ E   Q  K   E+E++A   +V   + + N  
Sbjct: 1124 SVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHL 1183

Query: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
             K  RE E+ I+E      +   S N      +    ELE  K +LE  L+  A  ++++
Sbjct: 1184 QKLFRE-ENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQA--EKMK 1240

Query: 1163 SKREQEVNILKKTLEEEA---KTHEAQIQ----------EMRQKHSQAVEELAEQLEQTK 1209
             K E+  N L ++ EEE    K  EAQ +          +  Q+  +A + L +Q E   
Sbjct: 1241 GKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETES 1300

Query: 1210 RVKANL--EKAKQTLENERGE------------LANEVKVLLQ--GKGDSEHKRKKVEAQ 1253
             VK N   E ++ TLEN   E            L ++VK L +  GK +  H     +  
Sbjct: 1301 EVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEY 1360

Query: 1254 LQELQVKFNEGERVRTELADKVTKLQVELDNVTGL--------LSQSDS-KSSKLTKDFS 1304
            L  LQ K  +  ++   L   +    V ++ + GL        +  +DS   + + K  S
Sbjct: 1361 LGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYADSLNDANMLK--S 1418

Query: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ 1358
             + S +   +++++E       LS  L       N  ++   EEE  KHN  +Q
Sbjct: 1419 LMNSTINGIKQVVKEHLEDFEMLSFWLSNTCHFLNCLKQYSGEEEFMKHNSPQQ 1472



 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 99/520 (19%), Positives = 230/520 (44%), Gaps = 54/520 (10%)

Query: 1046 LEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK 1105
            +++ ++KLE D    +  + E    +A L+    +K ++L+A L +            K+
Sbjct: 891  VQRLQKKLE-DQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKR 949

Query: 1106 IRE-LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ-ELRS 1163
             R+ +E ++++LQ+         ++ E QK  +  +L+    EL++ +D+   Q  +   
Sbjct: 950  YRDAVEEKLAKLQKH-------NSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQ 1002

Query: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
            K E++  +L+K+ E + + +E QIQ ++++    ++ L ++  Q + +          L+
Sbjct: 1003 KEERQRMLLEKSFELKTQDYEKQIQSLKEE----IKALKDEKMQLQHLVEGEHVTSDGLK 1058

Query: 1224 NERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVE-- 1281
             E   L+ +VK +     + E + + ++AQ  +++      +R   E   ++TK  +E  
Sbjct: 1059 AEVARLSKQVKTI----SEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESY 1114

Query: 1282 -LDNVTGLLSQSDSKSSK-----------LTKDFSALESQLQDTQELLQEENRQKLSLST 1329
             +++V   LS  D +              L K    LES  Q  ++  ++E     +L+ 
Sbjct: 1115 DIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIE---ALNF 1171

Query: 1330 KLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA----------QVADMKKKMED-SVG 1378
            K+  +  E N  ++   EE +   ++  ++  L +          Q+++++K+ +D  + 
Sbjct: 1172 KVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIR 1231

Query: 1379 CLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACN 1438
              E AE++K KL+ +L     R +E+     K  + +  +  +  + L+D   + Q A +
Sbjct: 1232 LNEQAEKMKGKLE-ELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASD 1290

Query: 1439 LEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERL 1498
              KKQ         E  +   + +E  R   E R+ E +     R +++  +Q   L + 
Sbjct: 1291 HLKKQ------FETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKT 1344

Query: 1499 NKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 1538
              +   ++      K+ +G   ++ E   + ++  + ++K
Sbjct: 1345 IGK-ANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLK 1383



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 109/501 (21%), Positives = 201/501 (40%), Gaps = 41/501 (8%)

Query: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-----SLARA----LEEAMEQKA 1493
            +++F  +      I   Y  +R + + E + KE   L     SLA      +E+  + +A
Sbjct: 872  RRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEA 931

Query: 1494 ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATED 1553
            ELE+     R   E     +D V + + +L+K    LE Q E+++ +L+E  +EL+   D
Sbjct: 932  ELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMD 991

Query: 1554 AKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE---LEDERKQRSMAVA 1610
              L  ++     K + +R L   ++  E K +   +Q++ ++ E   L+DE+ Q    V 
Sbjct: 992  -NLTKQLFDDVQKEERQRML--LEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVE 1048

Query: 1611 ARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKE 1670
                    LK   A +    K   E  K++  LQAQ  D  + +   +    E +++   
Sbjct: 1049 GEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEI-- 1106

Query: 1671 NEKKLKSMEAEMIQLQEELAAAERAKRQAQ----QERDELADEIANSSGKGALALEEK-- 1724
             ++ L+S + E ++ +  +   E      +     E  + A  +  S  +      EK  
Sbjct: 1107 TKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEI 1166

Query: 1725 RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLE 1784
              L  ++  L +E+   Q      ND     N  I    T L  E       +    +LE
Sbjct: 1167 EALNFKVVHLSQEINHLQKLFREEND----INESIRHEVTRLTSENMMIPDFKQQISELE 1222

Query: 1785 RQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKL 1844
            +Q ++L+++L E    +K K       LE    QL    + E  +R+A   Q      K 
Sbjct: 1223 KQKQDLEIRLNEQAEKMKGK-------LEELSNQLHRSQEEEGTQRKALEAQ-NEIHTKE 1274

Query: 1845 KDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDAT 1904
            K+ L+    E + A  +  +  +  + +K   RQ      EA R     R L+ EL+   
Sbjct: 1275 KEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQ------EASRLTLENRDLEEELDMKD 1328

Query: 1905 ETADAMNREVSSLKNKLRRGD 1925
                 +  +V +L   + + +
Sbjct: 1329 RVIKKLQDQVKTLSKTIGKAN 1349



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 102/534 (19%), Positives = 221/534 (41%), Gaps = 33/534 (6%)

Query: 1085 LQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEAL 1144
            L+   A + ++ A+  +A ++ + +   +  +Q     +R  +   ++ K + G      
Sbjct: 854  LEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHG------ 907

Query: 1145 KTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE-LAE 1203
               L + L S AA   LR+   +++  L+  LE+ A TH    +E  +++  AVEE LA+
Sbjct: 908  ---LVEKLTSLAA---LRAGDVEKIQKLEAELEKAA-THRRNYEEKGKRYRDAVEEKLAK 960

Query: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQE-LQVKFN 1262
              +    ++   E+ +  L+ +  EL  ++  L +   D   K ++    L++  ++K  
Sbjct: 961  LQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQ 1020

Query: 1263 EGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENR 1322
            + E+    L +++  L+ E   +  L+      S  L  + + L  Q++   E  +E   
Sbjct: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080

Query: 1323 QKLSLSTKLKQVEDEKNSFREQLEE-EEEAKHNLEKQIATLHAQVADMKKKMEDSV--GC 1379
             +       K V+ +K   RE++ E  ++   + + +       V D++   ED      
Sbjct: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFA 1140

Query: 1380 LETAEEVKRKLQKDLEGLSQRHEEKVAAYD----KLEKTKTRLQQ---ELDDLLVDLDHQ 1432
             E  ++  R L+   +     +E+++ A +     L +    LQ+   E +D+   + H+
Sbjct: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200

Query: 1433 RQSACNLEKKQKKFDQLLAE-EKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQ 1491
                 +       F Q ++E EK          ++AE    + E  +  L R+ EE   Q
Sbjct: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260

Query: 1492 KAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKS-------KRALEQQVEEMKTQLEEL 1544
            +  LE  N+    E E L+    ++ ++   L+K        K    Q+   +  +  +L
Sbjct: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320

Query: 1545 EDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
            E+EL   +    +L+  ++ +     +          ++   +++  RE EA+L
Sbjct: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score =  588 bits (1516), Expect = e-167
 Identities = 457/1719 (26%), Positives = 852/1719 (49%), Gaps = 169/1719 (9%)

Query: 22   AQADWAAKKLVWVPSDKSGFEPAS-LKEE---VGEEAI-VELVENGKKVKVNKDDIQKMN 76
            A+  W   + VW+   + GF  AS LK E   + E  + V+L  +G  + V++DD++K N
Sbjct: 342  AEEAWNETEKVWLVH-RDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400

Query: 77   PPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVE 136
             P   ++ED+A L  LNE+SVLH L++RY + L++TY+G   +V+ P     +YSE+++ 
Sbjct: 401  APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460

Query: 137  MYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS 196
            M+KG +R +M PHIYA+  TAYR+M+  R+DQSI+  G SG+GKT + + ++QYLA +A 
Sbjct: 461  MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520

Query: 197  SHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIET 256
               +K    E  + L     +LEAFGN+ T+ N N++RF + + ++FD  G +  A+I+T
Sbjct: 521  ISGNKVFSVEKWQALYT---LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQT 577

Query: 257  YLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDK 316
             LLEK R  R+   E TF++FYYLL+     L+T+L L    +        +  P ++ K
Sbjct: 578  MLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQK 637

Query: 317  --DMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKER-NTDQASMPDNTAAQK 373
                F +   AM+++GI  +EQ     +++ +  LG     KE     +     +  AQK
Sbjct: 638  AAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQK 697

Query: 374  VSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQ----------------ADFAIEAL 417
             ++LLG ++ + +  I   + K G   +Q++ +  Q                A   +E +
Sbjct: 698  AAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGM 755

Query: 418  AKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLN------SFEQLCINY 471
            A   Y  +F  LV  +N+AL  ++    S + I+D  GF+  +        SFE+LC NY
Sbjct: 756  AAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFEELCHNY 814

Query: 472  TNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPP--------- 522
            T ++LQ+LF+   F+ E E Y+ E IE  F D        +  +++ +            
Sbjct: 815  TQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTD 874

Query: 523  ---GILALLDEECWFPKATDKSFVEKVMQEQGTHP---KFQKPKQLKDKADFCII---HY 573
               G+L LL+EE   P A++ + +E++    G      K Q P     K    ++   H 
Sbjct: 875  EARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHG 934

Query: 574  AGKVDYKADEWL-MKNMDPLNDNIATLLHQSSDKFVSELW--KDVDRIIGLDQVAGM--- 627
               V+Y    WL     +P   N   LL  S  K +S L+  +     +    +AG+   
Sbjct: 935  TNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGG 994

Query: 628  SETALPGAFKTRKGMFRTVGQLYKEQLA--------KLMATLRNTNPNFVRCIIPNHEKK 679
            S+ AL  A   RK     +  + K+ L          L+ T++ +  +FV C +P  E  
Sbjct: 995  SQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGW 1054

Query: 680  AGK-----------------------------LDPHLVLDQLRCNGVLEGIRICRQGFPN 710
            AG+                             LD  L+  QLR + +L+ +R+ RQG+P+
Sbjct: 1055 AGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPD 1114

Query: 711  RVVFQEFRQRYEILTPNSIPKG-----FMDGKQACVLMIKALELDSNLYRIGQSKVFFRA 765
             +VF EFR+R+++L P+   K       +D ++A   +++ L+L+ +   +G S+VFFRA
Sbjct: 1115 HMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRA 1174

Query: 766  GVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNW 825
            G LA LEE+RD + +  +  FQA CRGYLAR+ F KR+ Q  A++ +Q+N      +++W
Sbjct: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDW 1234

Query: 826  QWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQL 885
             WW+LFT V+PL++V   EE++  K+EE+ ++R K   AE    E+     +L +   +L
Sbjct: 1235 PWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISEL 1294

Query: 886  QEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ-N 944
              +L  E      A +L    TA++   E+   +L+ + +  +++ + ++ E  + +   
Sbjct: 1295 TSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIR 1354

Query: 945  IQELEEQLEEEESARQ-KLQLEKVT-----TEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
              E+  +++++++  + +L+ E+       T+ +L++  E+++ +E QN      K+ LE
Sbjct: 1355 AAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN------KRQLE 1408

Query: 999  DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE---RLRREEKQRQELEKTRRKLEG 1055
             R+ +      + EE  ++L +LK K + +  +L++    L  ++ +  ELEK +R+ + 
Sbjct: 1409 RRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1465

Query: 1056 DSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA-RVEEEAAQKNMAL----KKIRELE 1110
            + +      A  +AQ  +L+ +  ++E+++  A A  ++++  +K+M +    +K+  LE
Sbjct: 1466 ELSQ-----AHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLE 1520

Query: 1111 SQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170
            +++ ++      + AS  K +KQ RDL  +++  + EL++   +    ++ + + E E+ 
Sbjct: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580

Query: 1171 ILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELA 1230
             +++T  +E ++ + +++E RQ   + ++++  QLE+    K  + + K+ LE +   L+
Sbjct: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLS 1640

Query: 1231 NEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLS 1290
            ++V      + D E   K++   L+  +    + + +   L +     + E+  +   L 
Sbjct: 1641 DQV-----NRRDFE-SEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR-EIAQLKNQLE 1693

Query: 1291 QSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE 1350
            +S+   +   K   A+E +++D    + +  + K +L  +L +++ EKN  + +LEE++E
Sbjct: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753

Query: 1351 AKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGL-SQRHEEKVAAYD 1409
              + L K+     AQ +    ++ D    LE A + K++LQ+ L+ L SQ    + +  D
Sbjct: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813

Query: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERD-RAE 1468
            K     +R + ++ +L   L+ +R          K+ + L +  K    K  EERD R  
Sbjct: 1814 K--SLVSRQEAKIRELETRLEFERTQV-------KRLESLASRLKENMEKLTEERDQRIA 1864

Query: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
            AE REK               EQ   L+R  +  + EM +L   + +  +  HELE    
Sbjct: 1865 AENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLE 1909

Query: 1529 ALEQQVEEMKTQLE---ELEDELQATEDAKLRLEVNLQAMKAQFERDLQGR-DEQSEEKK 1584
            +LE   + ++  L+   +   +LQA  + ++  + N   + ++ + D+    +++ +  K
Sbjct: 1910 SLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVK 1969

Query: 1585 KQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
              L +     +A  +D   + S   +  K L  D  D E
Sbjct: 1970 SWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDE 2008



 Score =  213 bits (543), Expect = 1e-54
 Identities = 203/796 (25%), Positives = 388/796 (48%), Gaps = 96/796 (12%)

Query: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
            V+ N++K K   +    +L   V+ L++ +   E  R K E ++Q+L+ K  + E+ R E
Sbjct: 1221 VQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNE 1279

Query: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
            L     +L+              S+ S+LT + +   +  +   +LL  E  ++L    +
Sbjct: 1280 LRLNSDRLE--------------SRISELTSELTDERNTGESASQLLDAETAERLRAEKE 1325

Query: 1331 LKQVEDEKNSFREQLEEEE-EAKHNLEKQIATLHAQVAD--------------------- 1368
            +K+++ + ++ ++Q+E  E E       + A ++ +V D                     
Sbjct: 1326 MKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFT 1385

Query: 1369 MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVD 1428
             K+  ++    LE  ++ KR+L++ L  L    EE   A  +L+K   RL  EL D  + 
Sbjct: 1386 KKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLH 1445

Query: 1429 LDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA 1488
            L+ Q+     LEKKQ++FD  L++    + +   +R++ + E      +A SL + LEE 
Sbjct: 1446 LEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEK 1505

Query: 1489 MEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDEL 1548
                A   +       E++D+ S +     S+ +++K  R LE +V++ + +L+E    +
Sbjct: 1506 DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI 1565

Query: 1549 QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMA 1608
            Q  E AKLRLE+ ++ M+    ++++ RDE+ EE ++   +++++ME +LE+E + +   
Sbjct: 1566 QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV 1625

Query: 1609 VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK----LQAQMKDCMRELDDTRASREEI 1664
            +  +++LE  L  L    D  N+   E+ K+LRK     +A + D    LD         
Sbjct: 1626 LREKRELEGKLATLS---DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDH-------- 1674

Query: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724
            L  +  +++++  ++ ++ + +   AAA +A++  + E ++L  +I +   K   ALEE+
Sbjct: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQI-DDIAKAKTALEEQ 1733

Query: 1725 -RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 1783
              RL+    +++  LEE+Q   E +N+ +KK    + Q + DL      AQ N+  + QL
Sbjct: 1734 LSRLQREKNEIQNRLEEDQ---EDMNELMKKHKAAVAQASRDL------AQIND-LQAQL 1783

Query: 1784 ERQNK---ELKVKLQEMEGTVK-----SKYKASITALEAKIAQLEEQLDNETKERQAACK 1835
            E  NK   EL+ KLQ ++  V+        K+ ++  EAKI +LE +L+ E    +   K
Sbjct: 1784 EEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE----RTQVK 1839

Query: 1836 QVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEE-----AQRAN 1890
            ++     +LK+ + ++ +ER   +Q     ++   + K+L+RQL + +EE      + A 
Sbjct: 1840 RLESLASRLKENMEKLTEER---DQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1896

Query: 1891 ASRRKLQRELEDATETADAMNREV-SSLKNKLRR-GDLPFVVPRRMAR-------KGAGD 1941
            ASR+K   ELE   E+ +A N+ + + LK   +R GDL   +   M            GD
Sbjct: 1897 ASRKK--HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGD 1954

Query: 1942 GS-DEEVDGKADGAEA 1956
               D E++ + DG ++
Sbjct: 1955 SDVDSELEDRVDGVKS 1970


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score =  588 bits (1515), Expect = e-167
 Identities = 457/1704 (26%), Positives = 847/1704 (49%), Gaps = 192/1704 (11%)

Query: 22   AQADWAAKKLVWVPSDKSGFEPAS-LKEE---VGEEAI-VELVENGKKVKVNKDDIQKMN 76
            A+  W   + VW+   + GF  AS LK E   + E  + V+L  +G  + V++DD++K N
Sbjct: 342  AEEAWNETEKVWLVH-RDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400

Query: 77   PPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVE 136
             P   ++ED+A L  LNE+SVLH L++RY + L++TY+G   +V+ P     +YSE+++ 
Sbjct: 401  APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460

Query: 137  MYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS 196
            M+KG +R +M PHIYA+  TAYR+M+  R+DQSI+  G SG+GKT + + ++QYLA +A 
Sbjct: 461  MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520

Query: 197  SHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIET 256
               +K    E  + L     +LEAFGN+ T+ N N++RF + + ++FD  G +  A+I+T
Sbjct: 521  ISGNKVFSVEKWQALYT---LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQT 577

Query: 257  YLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDK 316
             LLEK R  R+   E TF++FYYLL+     L+T+L L    +        +  P ++ K
Sbjct: 578  MLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQK 637

Query: 317  --DMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKER-NTDQASMPDNTAAQK 373
                F +   AM+++GI  +EQ     +++ +  LG     KE     +     +  AQK
Sbjct: 638  AAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQK 697

Query: 374  VSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQ----------------ADFAIEAL 417
             ++LLG ++ + +  I   + K G   +Q++ +  Q                A   +E +
Sbjct: 698  AAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGM 755

Query: 418  AKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLN------SFEQLCINY 471
            A   Y  +F  LV  +N+AL  ++    S + I+D  GF+  +        SFE+LC NY
Sbjct: 756  AAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFEELCHNY 814

Query: 472  TNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPP--------- 522
            T ++LQ+LF+   F+ E E Y+ E IE  F D        +  +++ +            
Sbjct: 815  TQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTD 874

Query: 523  ---GILALLDEECWFPKATDKSFVEKVMQEQGTHP---KFQKPKQLKDKADFCII---HY 573
               G+L LL+EE   P A++ + +E++    G      K Q P     K    ++   H 
Sbjct: 875  EARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHG 934

Query: 574  AGKVDYKADEWL-MKNMDPLNDNIATLLHQSSDKFVSELW--KDVDRIIGLDQVAGM--- 627
               V+Y    WL     +P   N   LL  S  K +S L+  +     +    +AG+   
Sbjct: 935  TNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGG 994

Query: 628  SETALPGAFKTRKGMFRTVGQLYKEQLA--------KLMATLRNTNPNFVRCIIPNHEKK 679
            S+ AL  A   RK     +  + K+ L          L+ T++ +  +FV C +P  E  
Sbjct: 995  SQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGW 1054

Query: 680  AGK-----------------------------LDPHLVLDQLRCNGVLEGIRICRQGFPN 710
            AG+                             LD  L+  QLR + +L+ +R+ RQG+P+
Sbjct: 1055 AGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPD 1114

Query: 711  RVVFQEFRQRYEILTPNSIPKG-----FMDGKQACVLMIKALELDSNLYRIGQSKVFFRA 765
             +VF EFR+R+++L P+   K       +D ++A   +++ L+L+ +   +G S+VFFRA
Sbjct: 1115 HMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRA 1174

Query: 766  GVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNW 825
            G LA LEE+RD + +  +  FQA CRGYLAR+ F KR+ Q  A++ +Q+N      +++W
Sbjct: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDW 1234

Query: 826  QWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQL 885
             WW+LFT V+PL++V   EE++  K+EE+ ++R K   AE    E+     +L +   +L
Sbjct: 1235 PWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISEL 1294

Query: 886  QEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ-N 944
              +L  E      A +L    TA++   E+   +L+ + +  +++ + ++ E  + +   
Sbjct: 1295 TSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIR 1354

Query: 945  IQELEEQLEEEESARQ-KLQLEKVT-----TEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
              E+  +++++++  + +L+ E+       T+ +L++  E+++ +E QN      K+ LE
Sbjct: 1355 AAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN------KRQLE 1408

Query: 999  DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE---RLRREEKQRQELEKTRRKLEG 1055
             R+ +      + EE  ++L +LK K + +  +L++    L  ++ +  ELEK +R+ + 
Sbjct: 1409 RRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1465

Query: 1056 DSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA-RVEEEAAQKNMAL----KKIRELE 1110
            + +      A  +AQ  +L+ +  ++E+++  A A  ++++  +K+M +    +K+  LE
Sbjct: 1466 ELSQ-----AHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLE 1520

Query: 1111 SQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170
            +++ ++      + AS  K +KQ RDL  +++  + EL++   +    ++ + + E E+ 
Sbjct: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580

Query: 1171 ILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELA 1230
             +++T  +E ++ + +++E RQ   + ++++  QLE+    K  + + K+ LE +   L+
Sbjct: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLS 1640

Query: 1231 NEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLS 1290
            ++V      + D E   K++   L+  +    + + +   L +     + E+  +   L 
Sbjct: 1641 DQV-----NRRDFE-SEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR-EIAQLKNQLE 1693

Query: 1291 QSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE 1350
            +S+   +   K   A+E +++D    + +  + K +L  +L +++ EKN  + +LEE++E
Sbjct: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753

Query: 1351 AKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGL-SQRHEEKVAAYD 1409
              + L K+     AQ +    ++ D    LE A + K++LQ+ L+ L SQ    + +  D
Sbjct: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813

Query: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERD-RAE 1468
            K     +R + ++ +L   L+ +R          K+ + L +  K    K  EERD R  
Sbjct: 1814 K--SLVSRQEAKIRELETRLEFERTQV-------KRLESLASRLKENMEKLTEERDQRIA 1864

Query: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
            AE REK               EQ   L+R  +  + EM +L   + +  +  HELE    
Sbjct: 1865 AENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLE 1909

Query: 1529 ALEQQVEEMKTQLE-----------ELEDELQATEDAKLRLEVN-LQAMKAQFERDLQGR 1576
            +LE   + ++  L+            +EDE+++ E+  L   +N LQ M  ++       
Sbjct: 1910 SLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDL---INSLQDMVTKY------- 1959

Query: 1577 DEQSEEKKKQLVRQVREMEAELED 1600
                 +K+K  +    ++++ELED
Sbjct: 1960 -----QKRKNKLEGDSDVDSELED 1978



 Score =  210 bits (535), Expect = 1e-53
 Identities = 197/766 (25%), Positives = 377/766 (49%), Gaps = 88/766 (11%)

Query: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
            V+ N++K K   +    +L   V+ L++ +   E  R K E ++Q+L+ K  + E+ R E
Sbjct: 1221 VQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNE 1279

Query: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
            L     +L+              S+ S+LT + +   +  +   +LL  E  ++L    +
Sbjct: 1280 LRLNSDRLE--------------SRISELTSELTDERNTGESASQLLDAETAERLRAEKE 1325

Query: 1331 LKQVEDEKNSFREQLEEEE-EAKHNLEKQIATLHAQVAD--------------------- 1368
            +K+++ + ++ ++Q+E  E E       + A ++ +V D                     
Sbjct: 1326 MKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFT 1385

Query: 1369 MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVD 1428
             K+  ++    LE  ++ KR+L++ L  L    EE   A  +L+K   RL  EL D  + 
Sbjct: 1386 KKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLH 1445

Query: 1429 LDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA 1488
            L+ Q+     LEKKQ++FD  L++    + +   +R++ + E      +A SL + LEE 
Sbjct: 1446 LEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEK 1505

Query: 1489 MEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDEL 1548
                A   +       E++D+ S +     S+ +++K  R LE +V++ + +L+E    +
Sbjct: 1506 DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI 1565

Query: 1549 QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMA 1608
            Q  E AKLRLE+ ++ M+    ++++ RDE+ EE ++   +++++ME +LE+E + +   
Sbjct: 1566 QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV 1625

Query: 1609 VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK----LQAQMKDCMRELDDTRASREEI 1664
            +  +++LE  L  L    D  N+   E+ K+LRK     +A + D    LD         
Sbjct: 1626 LREKRELEGKLATLS---DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDH-------- 1674

Query: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724
            L  +  +++++  ++ ++ + +   AAA +A++  + E ++L  +I +   K   ALEE+
Sbjct: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQI-DDIAKAKTALEEQ 1733

Query: 1725 -RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 1783
              RL+    +++  LEE+Q   E +N+ +KK    + Q + DL      AQ N+  + QL
Sbjct: 1734 LSRLQREKNEIQNRLEEDQ---EDMNELMKKHKAAVAQASRDL------AQIND-LQAQL 1783

Query: 1784 ERQNK---ELKVKLQEMEGTVK-----SKYKASITALEAKIAQLEEQLDNETKERQAACK 1835
            E  NK   EL+ KLQ ++  V+        K+ ++  EAKI +LE +L+ E    +   K
Sbjct: 1784 EEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE----RTQVK 1839

Query: 1836 QVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEE-----AQRAN 1890
            ++     +LK+ + ++ +ER   +Q     ++   + K+L+RQL + +EE      + A 
Sbjct: 1840 RLESLASRLKENMEKLTEER---DQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1896

Query: 1891 ASRRKLQRELEDATETADAMNREV-SSLKNKLRR-GDLPFVVPRRM 1934
            ASR+K   ELE   E+ +A N+ + + LK   +R GDL   +   M
Sbjct: 1897 ASRKK--HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEM 1940


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  587 bits (1512), Expect = e-167
 Identities = 471/1621 (29%), Positives = 771/1621 (47%), Gaps = 210/1621 (12%)

Query: 32   VWVPSDKSGFEPASLKEEVGE-EAIVELVENGKKVKVNKDDIQK------MNPPKFSKVE 84
            VW+P     +  A L ++  E +  ++L    + +     D+Q+       NP       
Sbjct: 13   VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72

Query: 85   DMAELTCLNEASVLHNLKERYY-SGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKR 143
            D+  L+ L+E +VLHNLK R+  S  IYTY G+  V INPY+ LPIY ++++  Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132

Query: 144  HEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD 203
             +M PHI+A+ + AY+ M +D ++QSI+ +GESGAGKT + K  ++Y A V  S      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS----AS 188

Query: 204  QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSR 263
            +  +E ++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD   +I+GAN+ TYLLEKSR
Sbjct: 189  ETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSR 248

Query: 264  AIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLS-NGHVTIPGQQDKDMFQET 322
             + QA +ER +HIFY L + AG     +L L     + + S  G  +I G  D + F++T
Sbjct: 249  VVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKT 308

Query: 323  MEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASM-PDNTAAQKVSHLLGIN 381
             +A  ++G+ E  QM + ++I+ +L LG++  + ER+ D  S+ P +        LLG+ 
Sbjct: 309  RQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLLGVE 368

Query: 382  VTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTK 441
             +     +   ++    +   K  + +Q   A  ALAK  Y ++F W+V  INKAL  + 
Sbjct: 369  HSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSL 428

Query: 442  RQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 501
            +Q  SFIG+LDI GFE F++NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I W  
Sbjct: 429  KQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTL 487

Query: 502  IDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQ 561
            IDF  D QPCIDLIE      GIL LLDEEC  PK TD+++ +K+     +   FQKP+ 
Sbjct: 488  IDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKPRM 543

Query: 562  LKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELW-KDVDRIIG 620
                  F I+H+A KV+Y +D +L KN D + +    +L  S    V++L+  D D +  
Sbjct: 544  --SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPA 601

Query: 621  LDQVAGMS-----ETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675
                 G S      +A P    + K   +TVG  ++  L  LM TL  T P++VRCI PN
Sbjct: 602  TTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPN 661

Query: 676  HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMD 735
             EK     DP   + QLR  GVLE IRI   G+P+R  + +F  RY +L          D
Sbjct: 662  DEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELANTD 720

Query: 736  GKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLA 795
             K  C  +++ L  D + ++ G++K+FFRAG +A+LE+ R  K     I  Q   RG+L 
Sbjct: 721  KKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQ 780

Query: 796  RKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPL-----LQVSRQEEEMMAK 850
            +    K  +   A   LQR C  +L  R  +  R       L     +Q +RQ  + + +
Sbjct: 781  K---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRR 837

Query: 851  EEELVK-------VRE--KQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEE 901
               +++       VR   +Q+  E++ T ++      MA +   + +  A    CA    
Sbjct: 838  AAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCA---- 893

Query: 902  LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQK 961
               R+   ++EL+ +   +EAR  E      HL+     M+  + +L+ +++E+    + 
Sbjct: 894  --FRMLKARRELKAL--RIEARSAE------HLKRLNVGMENKVVQLQRKIDEQNKEFKT 943

Query: 962  LQLE-KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT-NLTEEEEKSKSLA 1019
            L  +  VTT     ++E           +L KE    +    E T+  L EE E  ++  
Sbjct: 944  LSEQLSVTTSTYTMEVE-----------RLKKELVHYQQSPGEDTSLRLQEEVESLRTEL 992

Query: 1020 KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI-AELKMQL 1078
            +  +    ++ D   R      ++ EL K    LE ++  L D+  +L  QI  + K + 
Sbjct: 993  QRAHSERKILEDAHSR------EKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEF 1046

Query: 1079 AKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDL----ESERASRNKAEKQK 1134
            A+   +       +EEE ++    +K+  +LE +   L++++    ++    RN + +  
Sbjct: 1047 AQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSS 1106

Query: 1135 RDLGEELEALKT-ELEDTLDSTAAQQEL-RSKREQEVNILKK------TLEEEAKTHEAQ 1186
             +      ++ T E+ DT D+    +E+   K   ++ +  K       LE+E K  + Q
Sbjct: 1107 LESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQ 1166

Query: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHK 1246
            +++  Q+ S+ V+  AE  +    +  N + A  +L                       K
Sbjct: 1167 LEKREQQDSKKVQ--AEPPQTDIDLDPNADLAYNSL-----------------------K 1201

Query: 1247 RKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL 1306
            R+++E++ ++L+   NE   +R  +AD+ T+               ++ S      +S L
Sbjct: 1202 RQELESENKKLKNDLNE---LRKAVADQATQ---------------NNSSHGSPDSYSLL 1243

Query: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFRE-------QLEEEEEAKHNLEKQI 1359
             +QL+   E L+    + L L T++   +  + + R        +       KH  ++  
Sbjct: 1244 LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA 1303

Query: 1360 ATLHAQVADMKKKMEDSVGCLETAE---------EVKRKLQKDLEGLSQRHEEKVAAYDK 1410
               +  V     K ED     E  E         +V R L+  L+  S  HEE+V     
Sbjct: 1304 IEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEV----- 1358

Query: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
                   L+ +L+ L  ++D Q+Q+ C                                 
Sbjct: 1359 -----EHLKAQLEALKEEMDKQQQTFC--------------------------------- 1380

Query: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
                +T  LS    +E  ++Q             E+  L +   D+ + V +LEK++R L
Sbjct: 1381 ----QTLLLSPEAQVEFGVQQ-------------EISRLTNENLDLKELVEKLEKNERKL 1423

Query: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
            ++Q++    + ++LE      +  + R E+N Q    + E+D QG  E  +E +  L+R 
Sbjct: 1424 KKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRN 1483

Query: 1591 V 1591
            +
Sbjct: 1484 L 1484



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 121/641 (18%), Positives = 263/641 (41%), Gaps = 51/641 (7%)

Query: 1298 KLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK 1357
            K  ++  AL  + +  + L     R  + +  K+ Q++       EQ +E +     L  
Sbjct: 898  KARRELKALRIEARSAEHL----KRLNVGMENKVVQLQ---RKIDEQNKEFKTLSEQLSV 950

Query: 1358 QIATLHAQVADMKKKM---EDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
              +T   +V  +KK++   + S G     E+   +LQ+++E L    +   +    LE  
Sbjct: 951  TTSTYTMEVERLKKELVHYQQSPG-----EDTSLRLQEEVESLRTELQRAHSERKILEDA 1005

Query: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
             +R + EL   + DL+  +++A   ++K++  +Q+L + K   A+ + + +  + E  E+
Sbjct: 1006 HSREKDELRKRVADLE--QENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEE 1063

Query: 1475 ETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQV 1534
             ++  +L +          E  +L +++    +++   K   G   +   +S    +   
Sbjct: 1064 RSRYQNLVK----------EYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNY 1113

Query: 1535 EEMKT-QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
              + T ++ + ED LQ  E+  + LE     M    +   + R+ + E KK Q+  + RE
Sbjct: 1114 PSISTSEIGDTEDALQQVEE--IGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKRE 1171

Query: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAH-IDSANKNRDEAIKQLRKLQAQMKDCMR 1652
             +   + + +     +      ++    L+   ++S NK     + +LRK  A       
Sbjct: 1172 QQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNN 1231

Query: 1653 ELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIAN 1712
                +  S   +L Q K   ++L+  + E++ L+ ++ +A++ +   +     +    + 
Sbjct: 1232 SSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSW 1291

Query: 1713 SSGKGALALEEKRRLEARIAQLEEELEE-----EQGNTELINDRLKKANLQIDQINTDLN 1767
             + +  +  E+       + Q   + E+     E G   L    LK+    ++      +
Sbjct: 1292 PNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQS 1351

Query: 1768 LERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNET 1827
            LE  H ++ E+ + QLE   +E+  + Q    T+    +A +   E  + Q   +L NE 
Sbjct: 1352 LE--HEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQV---EFGVQQEISRLTNEN 1406

Query: 1828 KERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ 1887
             + +   +++ + E+KLK  L             K Q  +A+  L Q +R+  E   +  
Sbjct: 1407 LDLKELVEKLEKNERKLKKQL--------KIYMKKAQDLEAAQALAQSERKRHELNRQV- 1457

Query: 1888 RANASRRKLQRELEDATETADAMNRE-VSSLKNKLRRGDLP 1927
                  +  Q  LE   E    + R  V+ LK ++  G +P
Sbjct: 1458 TVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSGTVP 1498



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 116/532 (21%), Positives = 205/532 (38%), Gaps = 98/532 (18%)

Query: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA-----ELER 1497
            ++ F +L      I   +   + R E +A   E ++    + L   ME K      +++ 
Sbjct: 877  RRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE 936

Query: 1498 LNKQFRTEMEDLMSSKDDVGKSVHELEK------------SKRALEQQVEEMKTQLEELE 1545
             NK+F+T  E L  +       V  L+K            +   L+++VE ++T+L+   
Sbjct: 937  QNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAH 996

Query: 1546 DELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQR 1605
             E +  EDA  R +  L+   A    DL+  +   +++K+QL  Q+     + +DE  Q 
Sbjct: 997  SERKILEDAHSREKDELRKRVA----DLEQENALLKDEKEQLNNQIL---CQSKDEFAQN 1049

Query: 1606 SMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEIL 1665
            S+      K  +  K+LE    S  +N  +   QL +    ++D M  +  T   R    
Sbjct: 1050 SV------KENLMKKELEEE-RSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRN-- 1100

Query: 1666 AQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKR 1725
                 N+  L+S          E+   E A +Q ++   E          K A+ +    
Sbjct: 1101 ---PSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLE----------KAAMDMTVFL 1147

Query: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE-RSHAQKNENARQQLE 1784
            +L+ R+ +LE+E ++ Q   E   ++     +Q +   TD++L+  +    N   RQ+LE
Sbjct: 1148 KLQKRVRELEQERKKLQVQLEK-REQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELE 1206

Query: 1785 RQNKELKVKLQEMEGTVK-----------SKYKASITALEAKIAQLEEQLDNE---TKER 1830
             +NK+LK  L E+   V            S    S+   + K+A  E ++  E       
Sbjct: 1207 SENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRT 1266

Query: 1831 QAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADK----------------------- 1867
            Q      RR   +  +  +       N+E++ DQ D                        
Sbjct: 1267 QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNED 1326

Query: 1868 -----ASTRLKQLKRQLE--------EAEEEAQRANASRRKLQRELEDATET 1906
                 A   LKQ+ R LE        E EEE +   A    L+ E++   +T
Sbjct: 1327 GELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQT 1378


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  585 bits (1508), Expect = e-166
 Identities = 460/1515 (30%), Positives = 747/1515 (49%), Gaps = 188/1515 (12%)

Query: 32   VWVPSDKSGFEPASLKEEV--GEEAIVELVENGKKVKVNKDDIQK-----MNPPKFSKVE 84
            VW+P  +  ++ A L ++   G++ ++  +E GK ++ + D   K      NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 85   DMAELTCLNEASVLHNLKERYY-SGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKR 143
            D+  L+ L+E +VLHNL+ R+  S LIYTY G+  V INPY+ LPIY E+I+  Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 144  HEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD 203
             +M PHI+A+ + AY+ M +D  +QSI+ +GESGAGKT + K  ++Y A V+ S      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS----AS 188

Query: 204  QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSR 263
            +  +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD    I+GAN+ TYLLEKSR
Sbjct: 189  EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248

Query: 264  AIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFL-SNGHVTIPGQQDKDMFQET 322
             + QA+EER +HIFY L + A       L L   + + +    G   I G  D      T
Sbjct: 249  VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHT 308

Query: 323  MEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKV-SHLLGIN 381
             +A  ++GI E  QMG+ R+++G+L LGN+ F   R+ D  ++P       +   L+G++
Sbjct: 309  RQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLMGVD 367

Query: 382  VTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTK 441
              +    +   ++    +   K  +K QA  A +ALAK  Y ++F W+V  +N+AL    
Sbjct: 368  YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAV 427

Query: 442  RQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 501
            +Q  SFIG+LDI GFE F++NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I W  
Sbjct: 428  KQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTL 486

Query: 502  IDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTH----PKFQ 557
            IDF  D QPCI+LIE      GIL LLDEEC  PK TD ++ +K+     TH      F+
Sbjct: 487  IDF-YDNQPCINLIESKL---GILDLLDEECKMPKGTDDTWAQKL---YNTHLNKCALFE 539

Query: 558  KPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDR 617
            KP+ L +KA F I H+A KV+Y+ + +L KN D + +    +L  S  K + EL++D ++
Sbjct: 540  KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597

Query: 618  IIGLDQVAGMSETALPGA----FKTRKGMF-----RTVGQLYKEQLAKLMATLRNTNPNF 668
             I          T L        K R G       +TVG  ++  L  LM TL  T P++
Sbjct: 598  AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657

Query: 669  VRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNS 728
            VRCI PN  K     D    + QLR  GVLE IRI   GFP+R  +QEF  RY +L    
Sbjct: 658  VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQK 717

Query: 729  IPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQA 788
                  D KQ C  +++ L LD + Y+ G++K+FFRAG +A+LE+ R  K+    I  Q 
Sbjct: 718  --DVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775

Query: 789  CCRGYLARKAFAKRQQQLTAM-------------KVLQRNCAAYLKLRNWQWWRLFTKVK 835
              RG+L RK + + ++    M             K L+R  AA +  + W+ + +  + K
Sbjct: 776  TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYK 835

Query: 836  ------PLLQ------VSRQEEEMMAKEEELVKVREK--------------------QLA 863
                   +LQ      ++R     + +E + V ++++                    Q  
Sbjct: 836  IRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCC 895

Query: 864  AENRLTEMETLQSQLMAEKLQLQEQL---------QAETELCAEAEELRARLTAKKQELE 914
                + + E  + ++ A  ++  ++L         Q + ++  + ++ +  L  K   LE
Sbjct: 896  FRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKC-LVEKLTNLE 954

Query: 915  EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEK--VTTEAK 972
             I +    ++  + ER Q  + E K     +  L+E++ +     ++ + EK  +   A 
Sbjct: 955  GIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHAD 1014

Query: 973  LKKLEEEQII--LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEK-----SKSLAKLKNKH 1025
              K E EQ++  L+++N  L +EK+ L  RI +    +TE  EK     +K L    N  
Sbjct: 1015 RYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDE 1074

Query: 1026 EAMITDLEERLRREEKQRQELEKTRRKL---------EGDSTDLSDQIAEL-QAQIAELK 1075
                 +L     R E++  +L++    +           DST  S++   +  ++IAE+ 
Sbjct: 1075 RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEM- 1133

Query: 1076 MQLAKKEEELQAALARVEEEAAQKNMAL-----KKIRELESQISELQEDLE--SERASRN 1128
                   E++ +      E+    +M+L     K++ ELE +   +Q++L+   E+  R+
Sbjct: 1134 -------EDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRS 1186

Query: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS---KREQEVNILKKTLEEEAKTHEA 1185
            KA++++R    ++   + E E     +  +QEL S   K + E+N L+K L E++     
Sbjct: 1187 KAKEEER---PQIRGAELEYE-----SLKRQELESENKKLKNELNELRKALSEKS----- 1233

Query: 1186 QIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEH 1245
               E+    + A   L EQL     V   L+  K+ +   R +L ++ K  +Q K D ++
Sbjct: 1234 -APEVTAPGAPAYRVLMEQLTS---VSEELDVRKEEVLILRSQLVSQ-KEAIQPK-DDKN 1287

Query: 1246 KRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELD----NVTG-------------- 1287
                    L+++Q   ++GE  +  +  K T     LD    N  G              
Sbjct: 1288 TMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANR 1347

Query: 1288 -LLSQSDSKSSKLTKDFSALESQLQDTQE-------------LLQEENRQKLSLSTKLKQ 1333
             L SQ  S+      +  AL  ++Q  +E              L  E R + SL  ++ +
Sbjct: 1348 LLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITR 1407

Query: 1334 VEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKR----- 1388
            + +E     EQLE++++    L+KQ+     ++ +++    +++   +  +E  R     
Sbjct: 1408 LTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIP 1467

Query: 1389 KLQKDLEGLSQRHEE 1403
            + +KD +G+ +  +E
Sbjct: 1468 RKEKDFQGMLEYKKE 1482



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 120/562 (21%), Positives = 242/562 (43%), Gaps = 63/562 (11%)

Query: 1306 LESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK-QIATLHA 1364
            +E+++   Q  + E+N+    L  KL  +E   NS      E E+ + +LE+ Q++   A
Sbjct: 925  MENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS------ETEKLRSDLERLQLSEEEA 978

Query: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDD 1424
            +VA          G + + +E   KL+KDLE    R E+K      +E+   R +QE + 
Sbjct: 979  KVA---------TGRVLSLQEEIAKLRKDLE--QTRSEKKC-----IEEHADRYKQETEQ 1022

Query: 1425 LLVDLDHQRQSACNLEKKQKKFDQLLAEE-----KTISAKYAEERDRAEAEAREKETKAL 1479
            L+ +L  +      L+++++  +  + ++     +T+  K  EE  + E +  ++  +  
Sbjct: 1023 LVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQ 1079

Query: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
            +L        E+  +L    K+  T M  +         S H   +S+     ++ EM+ 
Sbjct: 1080 NLLNEFSRLEERYDDL----KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135

Query: 1540 QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1599
                 E+  +      + L + LQ    + E++ Q   ++ + K++Q++R   + E   +
Sbjct: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195

Query: 1600 DERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRA 1659
                +       R++LE + K L+  ++   K   E  K   ++ A      R L +   
Sbjct: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSE--KSAPEVTAPGAPAYRVLMEQLT 1253

Query: 1660 SREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGAL 1719
            S  E L   KE    L+S   +++  +E  A   +  +    +   L +++     KG +
Sbjct: 1254 SVSEELDVRKEEVLILRS---QLVSQKE--AIQPKDDKNTMTDSTILLEDVQKMKDKGEI 1308

Query: 1720 A-----LEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID-QINTDLNLERSHA 1773
            A     L+E  R  A    L+     E G   L+ + LK+AN  ++ Q+ +    +RSH 
Sbjct: 1309 AQAYIGLKETNRSSA----LDYHELNEDGELWLVYEGLKQANRLLESQLQSQ---KRSHE 1361

Query: 1774 QKNENARQQL----ERQNKELKVKLQEM----EGTVKSKYKASITALEAKIAQLEEQLDN 1825
             + E  R ++    E  N++ ++  Q +    E  +++  +  IT L  +   L EQL+ 
Sbjct: 1362 NEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEK 1421

Query: 1826 ETKERQAACKQVRRTEKKLKDV 1847
            + K  +   KQ++   KK+ ++
Sbjct: 1422 QDKTVRKLKKQLKVFAKKIGEL 1443



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 21/210 (10%)

Query: 1650 CMRELDDTRASRE-EILAQAKENEKKLK-SMEAEMIQLQEELAAAERAKRQAQQERDE-- 1705
            C R +   R  ++ +I A++ E  KKL   ME +++QLQ ++          +Q +D   
Sbjct: 895  CFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVD---------EQNKDYKC 945

Query: 1706 LADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTD 1765
            L +++ N  G      E+ R    R+   EEE +   G    + + + K    ++Q  ++
Sbjct: 946  LVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSE 1005

Query: 1766 LNLERSHAQKNENARQQ----LERQNKELKVKLQEMEGTVKSKYKASITALEAKIA---- 1817
                  HA + +   +Q    L+ +N  LK + + +   +  + K     +E K+     
Sbjct: 1006 KKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065

Query: 1818 QLEEQLDNETKERQAACKQVRRTEKKLKDV 1847
            QLE  L++E    Q    +  R E++  D+
Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDL 1095



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 30/164 (18%), Positives = 78/164 (47%), Gaps = 21/164 (12%)

Query: 1768 LERSHAQKNENA---------RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQ 1818
            L R+H +++ +A         R   +R+ K+LK++ + +E     +YK     +E KI Q
Sbjct: 877  LARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVE-----RYKKLHIGMENKIMQ 931

Query: 1819 LEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQ 1878
            L+ ++D + K+ +   +++   E        ++  +    +  +++A  A+ R+  L+ +
Sbjct: 932  LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEE 991

Query: 1879 LEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
            + +  ++ ++  + ++ ++       E AD   +E   L + L+
Sbjct: 992  IAKLRKDLEQTRSEKKCIE-------EHADRYKQETEQLVSNLK 1028



 Score = 37.4 bits (85), Expect = 0.15
 Identities = 32/160 (20%), Positives = 73/160 (45%), Gaps = 10/160 (6%)

Query: 1752 LKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV---KLQEMEGTVKSKYKAS 1808
            LKK  ++   +     L      K    +++++ QNK+ K    KL  +EG   S+ +  
Sbjct: 905  LKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKL 964

Query: 1809 ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKA 1868
             + LE ++   EE+    T    +  +++ +  K L+    +      +A++YK + ++ 
Sbjct: 965  RSDLE-RLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQL 1023

Query: 1869 STRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETAD 1908
             + LK+    L++ +E      A   ++ ++ ++ TET +
Sbjct: 1024 VSNLKEENTLLKQEKE------ALNHRIVQQAKEMTETME 1057


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  504 bits (1298), Expect = e-142
 Identities = 339/958 (35%), Positives = 520/958 (54%), Gaps = 69/958 (7%)

Query: 54  AIVELVENGKKVKVNKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNL 101
           A+V+L ++G+   V+ +D            I+ M+P     VEDM  L  LNEA +L NL
Sbjct: 26  AVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNL 85

Query: 102 KERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSM 161
             RY   LIYTY+G   V +NPY+ L IYS E +  Y  KK  EMPPHI+AI D  Y +M
Sbjct: 86  LIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNM 145

Query: 162 MQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAF 221
            ++  DQ  + +GESGAGKTE+TK ++Q+LA ++  H        +E+Q+L+A PILEAF
Sbjct: 146 KRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQH------SWIEQQVLEATPILEAF 199

Query: 222 GNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLL 281
           GNAKT++NDNSSRFGK+I I+F+  G I GA IE YLLEKSR  RQA +ER +H+FY +L
Sbjct: 200 GNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCML 259

Query: 282 SGAGEHLKTDLLLEPYNKYRFLSNGH-VTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLL 340
            G  E  K  L L   + Y +L+ G+ +T  G+ D   +     AM+++   + E   + 
Sbjct: 260 EGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEIS 319

Query: 341 RVISGVLQLGNIVFKKE--RNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGR 398
           ++++ +L LGN+ ++     N D   +  + +    + LL +N  D     LT R  + R
Sbjct: 320 KLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLITR 378

Query: 399 -DYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGAS----FIGILDI 453
            + V    ++EQA    +A  K  Y R+F W+V +IN A+ K   Q        IG+LDI
Sbjct: 379 GETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDI 438

Query: 454 AGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCID 513
            GFE F +NSFEQLCIN+ NE LQQ F   +F LEQEEY  E I+W  I+F  D Q  +D
Sbjct: 439 FGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDALD 497

Query: 514 LIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHY 573
           +I     P  I++L+DEE  FPK TD + + K+  +   +  +  PK    +  F I H+
Sbjct: 498 MIANK--PMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGINHF 554

Query: 574 AGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALP 633
           AG V Y+   +L KN D L+ +I  L+H S +KF+ ++++  D  +G +           
Sbjct: 555 AGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ-ADVAMGAE----------- 602

Query: 634 GAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLR 693
               TRK    T+   +K  L  LM TL    P FVRCI PN  KK    D HL + QLR
Sbjct: 603 ----TRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLR 657

Query: 694 CNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFM-DGKQACVLMIKALELDSN 752
            +G++E IRI R G+P R  F EF +RY +L P   P     D +  C  M +A+    +
Sbjct: 658 YSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHD 717

Query: 753 LYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVL 812
            ++IG++K+F +      LE ERD  ITD +I  Q   RG+  R  F K +   T   ++
Sbjct: 718 DWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT---LI 774

Query: 813 QRNCAAYLKLRNWQWWRL-FTKVKPLLQVSRQEEEMMAKEEELVKVREK------QLAAE 865
           QR+   +   +N+   RL F +++ L +  +  ++     + +++ + +      + A  
Sbjct: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFR 834

Query: 866 NRLTEMETLQSQLMAE-KLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARV 924
           +RL  + T+Q+        +L ++L+AE     EAE++R        E E++  ++ A+ 
Sbjct: 835 HRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKEMSAKK 888

Query: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQII 982
            +EE   +H   +++  Q   ++ E +L+E+E+AR+K +L +    A+ + +    ++
Sbjct: 889 AKEEAERKH---QERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMV 943



 Score = 31.6 bits (70), Expect = 8.0
 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 18/146 (12%)

Query: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL-EEQLDNETKERQAACKQVR 1838
            R + E+     + KL++     K+K +A     E ++AQL  E  + E KE++AA     
Sbjct: 866  RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQE-RLAQLAREDAERELKEKEAA----- 919

Query: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADK------ASTRLKQLKRQLEEAEEEAQRANAS 1892
               ++ K++L Q++  R     + D  DK       S  L   + Q     E+ +R    
Sbjct: 920  ---RRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGR-- 974

Query: 1893 RRKLQRELEDATETADAMNREVSSLK 1918
            R  ++ +L+ A    D    ++S  K
Sbjct: 975  REMVEEDLDAALPLPDEDEEDLSEYK 1000


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  504 bits (1298), Expect = e-142
 Identities = 339/958 (35%), Positives = 520/958 (54%), Gaps = 69/958 (7%)

Query: 54  AIVELVENGKKVKVNKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNL 101
           A+V+L ++G+   V+ +D            I+ M+P     VEDM  L  LNEA +L NL
Sbjct: 26  AVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNL 85

Query: 102 KERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSM 161
             RY   LIYTY+G   V +NPY+ L IYS E +  Y  KK  EMPPHI+AI D  Y +M
Sbjct: 86  LIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNM 145

Query: 162 MQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAF 221
            ++  DQ  + +GESGAGKTE+TK ++Q+LA ++  H        +E+Q+L+A PILEAF
Sbjct: 146 KRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQH------SWIEQQVLEATPILEAF 199

Query: 222 GNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLL 281
           GNAKT++NDNSSRFGK+I I+F+  G I GA IE YLLEKSR  RQA +ER +H+FY +L
Sbjct: 200 GNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCML 259

Query: 282 SGAGEHLKTDLLLEPYNKYRFLSNGH-VTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLL 340
            G  E  K  L L   + Y +L+ G+ +T  G+ D   +     AM+++   + E   + 
Sbjct: 260 EGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEIS 319

Query: 341 RVISGVLQLGNIVFKKE--RNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGR 398
           ++++ +L LGN+ ++     N D   +  + +    + LL +N  D     LT R  + R
Sbjct: 320 KLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLITR 378

Query: 399 -DYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGAS----FIGILDI 453
            + V    ++EQA    +A  K  Y R+F W+V +IN A+ K   Q        IG+LDI
Sbjct: 379 GETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDI 438

Query: 454 AGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCID 513
            GFE F +NSFEQLCIN+ NE LQQ F   +F LEQEEY  E I+W  I+F  D Q  +D
Sbjct: 439 FGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDALD 497

Query: 514 LIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHY 573
           +I     P  I++L+DEE  FPK TD + + K+  +   +  +  PK    +  F I H+
Sbjct: 498 MIANK--PMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGINHF 554

Query: 574 AGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALP 633
           AG V Y+   +L KN D L+ +I  L+H S +KF+ ++++  D  +G +           
Sbjct: 555 AGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ-ADVAMGAE----------- 602

Query: 634 GAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLR 693
               TRK    T+   +K  L  LM TL    P FVRCI PN  KK    D HL + QLR
Sbjct: 603 ----TRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLR 657

Query: 694 CNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFM-DGKQACVLMIKALELDSN 752
            +G++E IRI R G+P R  F EF +RY +L P   P     D +  C  M +A+    +
Sbjct: 658 YSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHD 717

Query: 753 LYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVL 812
            ++IG++K+F +      LE ERD  ITD +I  Q   RG+  R  F K +   T   ++
Sbjct: 718 DWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT---LI 774

Query: 813 QRNCAAYLKLRNWQWWRL-FTKVKPLLQVSRQEEEMMAKEEELVKVREK------QLAAE 865
           QR+   +   +N+   RL F +++ L +  +  ++     + +++ + +      + A  
Sbjct: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFR 834

Query: 866 NRLTEMETLQSQLMAE-KLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARV 924
           +RL  + T+Q+        +L ++L+AE     EAE++R        E E++  ++ A+ 
Sbjct: 835 HRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKEMSAKK 888

Query: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQII 982
            +EE   +H   +++  Q   ++ E +L+E+E+AR+K +L +    A+ + +    ++
Sbjct: 889 AKEEAERKH---QERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMV 943



 Score = 31.6 bits (70), Expect = 8.0
 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 18/146 (12%)

Query: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL-EEQLDNETKERQAACKQVR 1838
            R + E+     + KL++     K+K +A     E ++AQL  E  + E KE++AA     
Sbjct: 866  RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQE-RLAQLAREDAERELKEKEAA----- 919

Query: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADK------ASTRLKQLKRQLEEAEEEAQRANAS 1892
               ++ K++L Q++  R     + D  DK       S  L   + Q     E+ +R    
Sbjct: 920  ---RRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGR-- 974

Query: 1893 RRKLQRELEDATETADAMNREVSSLK 1918
            R  ++ +L+ A    D    ++S  K
Sbjct: 975  REMVEEDLDAALPLPDEDEEDLSEYK 1000


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  504 bits (1298), Expect = e-142
 Identities = 339/958 (35%), Positives = 520/958 (54%), Gaps = 69/958 (7%)

Query: 54  AIVELVENGKKVKVNKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNL 101
           A+V+L ++G+   V+ +D            I+ M+P     VEDM  L  LNEA +L NL
Sbjct: 26  AVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNL 85

Query: 102 KERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSM 161
             RY   LIYTY+G   V +NPY+ L IYS E +  Y  KK  EMPPHI+AI D  Y +M
Sbjct: 86  LIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNM 145

Query: 162 MQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAF 221
            ++  DQ  + +GESGAGKTE+TK ++Q+LA ++  H        +E+Q+L+A PILEAF
Sbjct: 146 KRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQH------SWIEQQVLEATPILEAF 199

Query: 222 GNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLL 281
           GNAKT++NDNSSRFGK+I I+F+  G I GA IE YLLEKSR  RQA +ER +H+FY +L
Sbjct: 200 GNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCML 259

Query: 282 SGAGEHLKTDLLLEPYNKYRFLSNGH-VTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLL 340
            G  E  K  L L   + Y +L+ G+ +T  G+ D   +     AM+++   + E   + 
Sbjct: 260 EGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEIS 319

Query: 341 RVISGVLQLGNIVFKKE--RNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGR 398
           ++++ +L LGN+ ++     N D   +  + +    + LL +N  D     LT R  + R
Sbjct: 320 KLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLITR 378

Query: 399 -DYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGAS----FIGILDI 453
            + V    ++EQA    +A  K  Y R+F W+V +IN A+ K   Q        IG+LDI
Sbjct: 379 GETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDI 438

Query: 454 AGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCID 513
            GFE F +NSFEQLCIN+ NE LQQ F   +F LEQEEY  E I+W  I+F  D Q  +D
Sbjct: 439 FGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDALD 497

Query: 514 LIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHY 573
           +I     P  I++L+DEE  FPK TD + + K+  +   +  +  PK    +  F I H+
Sbjct: 498 MIANK--PMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGINHF 554

Query: 574 AGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALP 633
           AG V Y+   +L KN D L+ +I  L+H S +KF+ ++++  D  +G +           
Sbjct: 555 AGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ-ADVAMGAE----------- 602

Query: 634 GAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLR 693
               TRK    T+   +K  L  LM TL    P FVRCI PN  KK    D HL + QLR
Sbjct: 603 ----TRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLR 657

Query: 694 CNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFM-DGKQACVLMIKALELDSN 752
            +G++E IRI R G+P R  F EF +RY +L P   P     D +  C  M +A+    +
Sbjct: 658 YSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHD 717

Query: 753 LYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVL 812
            ++IG++K+F +      LE ERD  ITD +I  Q   RG+  R  F K +   T   ++
Sbjct: 718 DWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT---LI 774

Query: 813 QRNCAAYLKLRNWQWWRL-FTKVKPLLQVSRQEEEMMAKEEELVKVREK------QLAAE 865
           QR+   +   +N+   RL F +++ L +  +  ++     + +++ + +      + A  
Sbjct: 775 QRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFR 834

Query: 866 NRLTEMETLQSQLMAE-KLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARV 924
           +RL  + T+Q+        +L ++L+AE     EAE++R        E E++  ++ A+ 
Sbjct: 835 HRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKEMSAKK 888

Query: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQII 982
            +EE   +H   +++  Q   ++ E +L+E+E+AR+K +L +    A+ + +    ++
Sbjct: 889 AKEEAERKH---QERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMV 943



 Score = 31.6 bits (70), Expect = 8.0
 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 18/146 (12%)

Query: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL-EEQLDNETKERQAACKQVR 1838
            R + E+     + KL++     K+K +A     E ++AQL  E  + E KE++AA     
Sbjct: 866  RLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQE-RLAQLAREDAERELKEKEAA----- 919

Query: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADK------ASTRLKQLKRQLEEAEEEAQRANAS 1892
               ++ K++L Q++  R     + D  DK       S  L   + Q     E+ +R    
Sbjct: 920  ---RRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGR-- 974

Query: 1893 RRKLQRELEDATETADAMNREVSSLK 1918
            R  ++ +L+ A    D    ++S  K
Sbjct: 975  REMVEEDLDAALPLPDEDEEDLSEYK 1000


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  496 bits (1276), Expect = e-139
 Identities = 331/959 (34%), Positives = 530/959 (55%), Gaps = 59/959 (6%)

Query: 63   KKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVIN 122
            K+  +    +  M+P     V+DMA LT L+  S+++NL +RY    IYTY G     +N
Sbjct: 45   KQSTITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVN 104

Query: 123  PYKNLP-IYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKT 181
            PY+ +  +Y    +E Y  +   E+PPHI+AI +  YR + +  ++Q IL +GESGAGKT
Sbjct: 105  PYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKT 164

Query: 182  ENTKKVIQYLAYVASSHKS---KKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKF 238
            E+TK ++++L+ ++        K+    +ER +L+++PI+EAFGNAKTV N+NSSRFGKF
Sbjct: 165  ESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKF 224

Query: 239  IRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYN 298
            +++N    G I G  I  YLLEK+R +RQ   ER +HIFY LL+G     + +  L    
Sbjct: 225  VQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPE 284

Query: 299  KYRFLS-NGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKE 357
             Y +L+ +G V      D++ F+E + AM +M   +EE   + R+++G+L LGNI F   
Sbjct: 285  NYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF--- 341

Query: 358  RNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEAL 417
                 A +   TA  + + LLG++ T  T  +    + +  + +      +QA  + ++L
Sbjct: 342  ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSL 401

Query: 418  AKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQ 477
            A A Y   F W++ +IN  +     +    IGILDI GFE F++N FEQ  INY NEKLQ
Sbjct: 402  AMALYACCFEWVIKKINSRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQ 459

Query: 478  QLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKA 537
            + FN  +F LEQ EY REG+ W  ID+ +D   C+DLIEK     G+LAL++EE  FP+A
Sbjct: 460  EYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL---GLLALINEESHFPQA 515

Query: 538  TDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIA 597
            TD + +EK+  +   +  + KP+   +  +F + HYAG+V Y     L KN D   D++ 
Sbjct: 516  TDSTLLEKLHSQHANNHFYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLL 573

Query: 598  TLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKL 657
             LL +S   F+ +L++ V      D +   S+   P           TV   +K+ L  L
Sbjct: 574  NLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRP-----------TVSSQFKDSLHSL 622

Query: 658  MATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEF 717
            MATL ++NP FVRCI PN +K   + D  +VL+QLR +G+LE +RI + G+  R  FQ+F
Sbjct: 623  MATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDF 682

Query: 718  RQRYEILTPN-SIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERD 776
             +RY++L  N ++P+   D +  C  +++  +  ++ +++G++KVF R  +   LE+ R+
Sbjct: 683  YKRYKVLMRNLALPE---DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRRE 739

Query: 777  LKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKP 836
             +++   +  +A   G+LARK + K    L  + ++Q+N  A+L  R     R     K 
Sbjct: 740  EEVSHAAMVIRAHVLGFLARKQYRK---VLYCVVIIQKNYRAFLLRR-----RFLHLKKA 791

Query: 837  LLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELC 896
             +   +Q    +A+      + EK+   E +  E E  + +   E+ + +E+ + E EL 
Sbjct: 792  AIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEE--EKKKREEEERERERERREAELR 849

Query: 897  AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ-QNIQELEEQLEEE 955
            A+ EE     T K+QELE +      + ++E E  + L+ +K+  Q + I  LE+++E+ 
Sbjct: 850  AQQEE----ETRKQQELEAL-----QKSQKEAELTRELEKQKENKQVEEILRLEKEIEDL 900

Query: 956  ESARQKLQLEKVTTEAKLKKLEE----EQIILEDQNCKLAKE--KKLLEDRIAEFTTNL 1008
            +  R K Q E   TEA L+KL+E    E   LE++ C+ A+E  + L  D I E   N+
Sbjct: 901  Q--RMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNI 957



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 49/199 (24%), Positives = 94/199 (47%), Gaps = 26/199 (13%)

Query: 1431 HQRQSACNLEKK------QKKFDQLLAEEKTISAKYAEERDRA-----EAEAREKETKAL 1479
            H +++A   +K+      ++ + QLLAE++    K  +E +       E   RE+E +  
Sbjct: 787  HLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREA 846

Query: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
             L    EE   ++ ELE L K          S K+   +   ELEK K    +QVEE+  
Sbjct: 847  ELRAQQEEETRKQQELEALQK----------SQKE--AELTRELEKQKE--NKQVEEILR 892

Query: 1540 QLEELEDELQATEDAKLRL-EVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
              +E+ED  +  E  +L L E +LQ ++ + +++L+  +E++    ++ +  +   E + 
Sbjct: 893  LEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDE 952

Query: 1599 EDERKQRSMAVAARKKLEM 1617
                 +RS++V +    E+
Sbjct: 953  CVRNIERSLSVGSEFSSEL 971



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 42/163 (25%), Positives = 80/163 (49%), Gaps = 20/163 (12%)

Query: 1090 ARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELE 1149
            A V ++  +  +A +  R+L ++  E +E  + E   + K E+++R+   E E  + EL 
Sbjct: 792  AIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERE--RERERREAELR 849

Query: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK 1209
                   AQQE  ++++QE+  L+K+ +E   T E +    +QK ++ VEE+        
Sbjct: 850  -------AQQEEETRKQQELEALQKSQKEAELTRELE----KQKENKQVEEIL------- 891

Query: 1210 RVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEA 1252
            R++  +E  ++  E +   L       LQ + D E +R + EA
Sbjct: 892  RLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEA 934



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 48/161 (29%), Positives = 79/161 (49%), Gaps = 15/161 (9%)

Query: 1018 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK-M 1076
            LA+ + + E    + EE+ +REE++R E E+ RR+ E     L  Q  E   +  EL+ +
Sbjct: 812  LAEKREQEEKKKQEEEEKKKREEEER-ERERERREAE-----LRAQQEEETRKQQELEAL 865

Query: 1077 QLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRD 1136
            Q ++KE EL   L     E  ++N  +++I  LE +I +LQ   E +  S  +A  QK  
Sbjct: 866  QKSQKEAELTREL-----EKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ 920

Query: 1137 LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE 1177
               + E  + E E      AAQ+ L S    E++   + +E
Sbjct: 921  ERRDQELRRLEEE---ACRAAQEFLESLNFDEIDECVRNIE 958



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 53/240 (22%), Positives = 100/240 (41%), Gaps = 37/240 (15%)

Query: 1672 EKKLKSMEAEMI--QLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1729
            +K+L+   A  +  QL  E    E  K+Q ++E+ +  +E             E+ R EA
Sbjct: 796  QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERE---------RERERREA 846

Query: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKE 1789
             +   +EE   +Q   E +    K+A L                   E  +Q+  +Q +E
Sbjct: 847  ELRAQQEEETRKQQELEALQKSQKEAEL-----------------TRELEKQKENKQVEE 889

Query: 1790 LKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKE-RQAACKQVRRTEKKLKDVL 1848
            +    +E+E   + K +  ++  EA + +L+E+ D E +   + AC+  +   + L    
Sbjct: 890  ILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLN--F 947

Query: 1849 LQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETAD 1908
             ++D+  RN E+      + S+ L       E A EE    N S+   + E+++  E  D
Sbjct: 948  DEIDECVRNIERSLSVGSEFSSEL------AESACEEKPNFNFSQPYPEEEVDEGFEADD 1001



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 40/175 (22%), Positives = 85/175 (48%), Gaps = 10/175 (5%)

Query: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
            +L+ QIA    +    E+  Q    + EEE  +K    ++ RE E + +EL+   E E  
Sbjct: 798  QLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETR 857

Query: 1126 SRNKAE-----KQKRDLGEELEALK--TELEDTLDSTAAQQEL-RSKREQEVNILKKTLE 1177
             + + E     +++ +L  ELE  K   ++E+ L      ++L R K +QE+++ + +L+
Sbjct: 858  KQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQ 917

Query: 1178 EEAKTHEAQIQEMRQKHSQAVEELAEQL--EQTKRVKANLEKAKQTLENERGELA 1230
            +  +  + +++ + ++  +A +E  E L  ++      N+E++         ELA
Sbjct: 918  KLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELA 972



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 12/137 (8%)

Query: 1663 EILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA----QQERDELADEIANSSGKGA 1718
            ++LA+ +E E+K K  E E  + +EE    ER +R+A    QQE +    +   +  K  
Sbjct: 810  QLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQ 869

Query: 1719 LALEEKRRLEAR--------IAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
               E  R LE +        I +LE+E+E+ Q   E     L +A+LQ  Q   D  L R
Sbjct: 870  KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRR 929

Query: 1771 SHAQKNENARQQLERQN 1787
               +    A++ LE  N
Sbjct: 930  LEEEACRAAQEFLESLN 946



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 42/192 (21%), Positives = 86/192 (44%), Gaps = 31/192 (16%)

Query: 1560 VNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDL 1619
            ++L+     F++ L+G  + +    +QL+ + RE E + + E +++       ++ E + 
Sbjct: 786  LHLKKAAIVFQKQLRG--QIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERER 843

Query: 1620 KDLEAHIDSANKNRDEAIKQLRKLQAQMKDC--MRELDDTRASR--EEILAQAKENEKKL 1675
            ++ E       + R +  ++L  LQ   K+    REL+  + ++  EEIL   KE E   
Sbjct: 844  REAELRAQQEEETRKQ--QELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIE--- 898

Query: 1676 KSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLE 1735
               + + ++ Q+EL+  E + ++ Q+ RD                 +E RRLE    +  
Sbjct: 899  ---DLQRMKEQQELSLTEASLQKLQERRD-----------------QELRRLEEEACRAA 938

Query: 1736 EELEEEQGNTEL 1747
            +E  E     E+
Sbjct: 939  QEFLESLNFDEI 950



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 42/186 (22%), Positives = 80/186 (43%), Gaps = 20/186 (10%)

Query: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDL-----KDLEA 1624
            +R+ + + +Q EE+KK+   + RE E E  +   +       RK+ E++      K+ E 
Sbjct: 815  KREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAEL 874

Query: 1625 HIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQ 1684
              +   +  ++ ++++ +L+ +++D  R  +    S  E   Q  +  +     + E+ +
Sbjct: 875  TRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERR-----DQELRR 929

Query: 1685 LQEEL--AAAERAKRQAQQERDELADEIANSSGKGA--------LALEEKRRLEARIAQL 1734
            L+EE   AA E  +     E DE    I  S   G+         A EEK          
Sbjct: 930  LEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYP 989

Query: 1735 EEELEE 1740
            EEE++E
Sbjct: 990  EEEVDE 995



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 15/154 (9%)

Query: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLE 1440
            E  E+ ++K Q++ E   +  EE+       E+ + R + EL     +   ++Q    L+
Sbjct: 814  EKREQEEKKKQEEEEKKKREEEER-------ERERERREAELRAQQEEETRKQQELEALQ 866

Query: 1441 KKQKKFDQLLAEEKTISAKYAEERDRAEAE----AREKETKALSLARALEEAMEQK--AE 1494
            K QK+ +     EK    K  EE  R E E     R KE + LSL  A  + ++++   E
Sbjct: 867  KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926

Query: 1495 LERLNKQFRTEMEDLMSSK--DDVGKSVHELEKS 1526
            L RL ++     ++ + S   D++ + V  +E+S
Sbjct: 927  LRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960



 Score = 37.4 bits (85), Expect = 0.15
 Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 12/189 (6%)

Query: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK-QIATLHAQ 1365
            E + Q+ ++  +EE ++K     + ++ E  +   R Q EEE   +  LE  Q +   A+
Sbjct: 814  EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAE 873

Query: 1366 VADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL 1425
            +    +K +++    +  EE+ R L+K++E L +  E++  +    E +  +LQ+  D  
Sbjct: 874  LTRELEKQKEN----KQVEEILR-LEKEIEDLQRMKEQQELSL--TEASLQKLQERRDQE 926

Query: 1426 LVDLDHQRQSACNLEKKQKKFDQL----LAEEKTISAKYAEERDRAEAEAREKETKALSL 1481
            L  L+ +   A     +   FD++       E+++S       + AE+   EK     S 
Sbjct: 927  LRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQ 986

Query: 1482 ARALEEAME 1490
                EE  E
Sbjct: 987  PYPEEEVDE 995



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 44/183 (24%), Positives = 81/183 (44%), Gaps = 21/183 (11%)

Query: 1156 AAQQELRSKREQEVNILKKTLEE----EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211
            A ++E   K++QE    KK  EE    E +  EA+++  +++ ++  +EL    +  K  
Sbjct: 813  AEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEA 872

Query: 1212 KANLEKAKQTLENERGE----LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERV 1267
            +   E  KQ  EN++ E    L  E++ L + K   + +    EA LQ+LQ + ++  R 
Sbjct: 873  ELTRELEKQK-ENKQVEEILRLEKEIEDLQRMK--EQQELSLTEASLQKLQERRDQELRR 929

Query: 1268 RTELADKVTKLQVE----------LDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELL 1317
              E A +  +  +E          + N+   LS     SS+L +     +     +Q   
Sbjct: 930  LEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYP 989

Query: 1318 QEE 1320
            +EE
Sbjct: 990  EEE 992


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,251,576
Number of Sequences: 37866
Number of extensions: 3203202
Number of successful extensions: 97803
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1062
Number of HSP's successfully gapped in prelim test: 1737
Number of HSP's that attempted gapping in prelim test: 16433
Number of HSP's gapped (non-prelim): 23643
length of query: 1960
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1843
effective length of database: 13,817,196
effective search space: 25465092228
effective search space used: 25465092228
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.