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Search of human proteins with 42491362
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42491362 IKK interacting protein isoform 2 [Homo sapiens]
(350 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42491362 IKK interacting protein isoform 2 [Homo sapiens] 672 0.0
gi|24233517 IKK interacting protein isoform 1 [Homo sapiens] 238 6e-63
gi|42476085 IKK interacting protein isoform 3.1 [Homo sapiens] 123 2e-28
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 53 4e-07
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 51 1e-06
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 50 4e-06
gi|18641360 collectin sub-family member 12 [Homo sapiens] 49 7e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens] 49 7e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 47 2e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 47 3e-05
gi|118498362 kinectin 1 isoform b [Homo sapiens] 47 3e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 47 3e-05
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 47 3e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 47 3e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 46 6e-05
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 46 6e-05
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 46 6e-05
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 46 6e-05
gi|38044112 restin isoform b [Homo sapiens] 45 7e-05
gi|4506751 restin isoform a [Homo sapiens] 45 7e-05
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 45 1e-04
gi|110611228 utrophin [Homo sapiens] 45 1e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 45 1e-04
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 45 1e-04
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa... 45 1e-04
gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa... 45 1e-04
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa... 45 1e-04
gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo sa... 45 1e-04
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 45 1e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens] 44 2e-04
>gi|42491362 IKK interacting protein isoform 2 [Homo sapiens]
Length = 350
Score = 672 bits (1735), Expect = 0.0
Identities = 350/350 (100%), Positives = 350/350 (100%)
Query: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW 60
MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW
Sbjct: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW 60
Query: 61 FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLK 120
FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLK
Sbjct: 61 FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLK 120
Query: 121 RLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIR 180
RLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIR
Sbjct: 121 RLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIR 180
Query: 181 RISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRIN 240
RISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRIN
Sbjct: 181 RISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRIN 240
Query: 241 SVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVND 300
SVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVND
Sbjct: 241 SVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVND 300
Query: 301 LTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEIAHISDMN 350
LTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEIAHISDMN
Sbjct: 301 LTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEIAHISDMN 350
>gi|24233517 IKK interacting protein isoform 1 [Homo sapiens]
Length = 377
Score = 238 bits (607), Expect = 6e-63
Identities = 136/353 (38%), Positives = 216/353 (61%), Gaps = 15/353 (4%)
Query: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW 60
MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW
Sbjct: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAW 60
Query: 61 FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLK 120
FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEK + +E+I+++ S + +
Sbjct: 61 FVFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKLESTESILQEATSSMSL--MT 118
Query: 121 RLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIR 180
+ ++E++ ++ + I +++L + +L++ + +++ + K++ +
Sbjct: 119 QFEQEVSNLQDIMHDIQNNEEVLTQRMQSLNEKFQNITDFWKRSLEEMNINTDIFKSEAK 178
Query: 181 RISGLVT-DVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRI 239
I VT + S ++ L +++ +E +T++NI + + + + +++ I
Sbjct: 179 HIHSQVTVQINSAEQEIKLLTERLKDLEDSTLRNIRTVKRQEEEDLLRVEEQLGSDTKAI 238
Query: 240 NSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYN---LKKDFSRLEP 296
+++ E + F + D L KV + T ++ +++ + +D E
Sbjct: 239 EKLEE---EQHALFARDEDLTNKLSDYEPKVEECKTHLPTIESAIHSVLRVSQDLIETEK 295
Query: 297 LVNDLTLRIGRLVTDLLQREKEIAFLSEKI------SNLTIVQAEIKDIKDEI 343
+ DLT+++ + D+L+ EI + + + +++ +Q E+ +K+++
Sbjct: 296 KMEDLTMQMFNMEDDMLKAVSEIMEMQKTLEGIQYDNSILKMQNELDILKEKV 348
>gi|42476085 IKK interacting protein isoform 3.1 [Homo sapiens]
Length = 70
Score = 123 bits (309), Expect = 2e-28
Identities = 59/59 (100%), Positives = 59/59 (100%)
Query: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA 59
MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA
Sbjct: 1 MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA 59
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 53.1 bits (126), Expect = 4e-07
Identities = 60/292 (20%), Positives = 124/292 (42%), Gaps = 45/292 (15%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSF-----QIIAH 118
Q++EK VEN+ LK + + +++ L +EK + + +E+
Sbjct: 504 QENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVR 563
Query: 119 LKR----LQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITS 174
L++ + + I+++++ + + E+ IL NS + +D ++ + +D G
Sbjct: 564 LRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRG----- 618
Query: 175 VKTDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSS--------IDRTA 226
D I L + SL + V+ L++ +EKVE K D+L+ S ID
Sbjct: 619 --HDSEMIGDLQARITSLQEEVKHLKHNLEKVEGER-KEAQDMLNHSEKEKNNLEIDLNY 675
Query: 227 TLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYN 286
L+ Q +N K T L TD+ S+E ++ + +++ K+
Sbjct: 676 KLKSLQQRLEQEVNEHKVTKARL-------TDKHQSIEEAKSVAM------CEMEKKLKE 722
Query: 287 LKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAFLS-------EKISNLTI 331
++ + E V + + L DL Q ++++ L+ +++ NLT+
Sbjct: 723 EREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTL 774
Score = 36.2 bits (82), Expect = 0.045
Identities = 67/297 (22%), Positives = 119/297 (40%), Gaps = 53/297 (17%)
Query: 66 SEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKS-------EAIMEQLKS------ 112
++K + Q + KLE +QL +++ L E QK + IM++L
Sbjct: 420 ADKSLQESLQKTIYKLE----EQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR 475
Query: 113 ------FQIIAHLKRLQEEINEVKTWSNRITEKQDILNNSLTTLS---QDITKVDQST-- 161
QI LQ INE + + + EK+ + N ++TL +D+ KV Q++
Sbjct: 476 NLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQL 535
Query: 162 -----TSMAKDV----GLKITSVKTDIR------RISGLVTDVISLTDSVQELENKIEKV 206
+ + K + L T T +R +S ++ + SL +QE +E
Sbjct: 536 ANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENS 595
Query: 207 EKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGD 266
+ T K+ L + R+ +S+ I ++ +T L+ + +EG+
Sbjct: 596 KSQTDKDYYQLQAI----LEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGE 651
Query: 267 RAKVLKTVTFANDLKPKV-----YNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKE 318
R + + + K + Y LK RLE VN+ + RL TD Q +E
Sbjct: 652 RKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARL-TDKHQSIEE 707
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 51.2 bits (121), Expect = 1e-06
Identities = 59/262 (22%), Positives = 116/262 (44%), Gaps = 23/262 (8%)
Query: 70 AKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQL--KSFQIIAHLKRLQEEIN 127
AK + + L E LQ ++ SE +E +QL FQ+ A +K + E
Sbjct: 869 AKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAE 928
Query: 128 EVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVT 187
+ + + +T K+ L + + L +DI ++ + + K+ VK +SGL
Sbjct: 929 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDE 988
Query: 188 DVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLT 247
+ LT + L+ ++ D L + D+ +L KT S+ Q++ ++ +L
Sbjct: 989 TIAKLTREKKALQEAHQQAL--------DDLQAEEDKVNSLNKTKSKLEQQVEDLESSLE 1040
Query: 248 E---LKSDFDKHTDRFLSLEGDRAKVLKTV-TFANDLKPKVYNLKK---DFSRLEPLVND 300
+ L+ D +++ + LEGD +++ ND + LKK ++ +L+ V D
Sbjct: 1041 QEKKLRVDLERNKRK---LEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVED 1097
Query: 301 ---LTLRIGRLVTDLLQREKEI 319
L L+ + + +L R +E+
Sbjct: 1098 EQTLGLQFQKKIKELQARIEEL 1119
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 49.7 bits (117), Expect = 4e-06
Identities = 58/280 (20%), Positives = 125/280 (44%), Gaps = 30/280 (10%)
Query: 68 KFAKVENQYQLLKLETNEFQ-QLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEI 126
K ++E + L E N+ Q Q+QS+ +++ ++ E +++ Q+ A +K + E
Sbjct: 872 KRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKN--KIQLEAKIKEVTERA 929
Query: 127 NEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLV 186
E + + +T K+ L + + L +DI ++ + + K+ VK ++GL
Sbjct: 930 EEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 989
Query: 187 TDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTL 246
+ L +K +K + T + D L + D+ L K ++ Q+++ ++ +L
Sbjct: 990 ETIAKL--------SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSL 1041
Query: 247 TE---LKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTL 303
+ L+ D ++ + LEGD LK + +++ D +L+ +
Sbjct: 1042 EQEKKLRMDLERAKRK---LEGD----LKLA------QESTMDMENDKQQLDEKLEKKEF 1088
Query: 304 RIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEI 343
I L++ + + L +KI L QA I+++ +EI
Sbjct: 1089 EISNLISKIEDEQAVEIQLQKKIKEL---QARIEELGEEI 1125
Score = 42.0 bits (97), Expect = 8e-04
Identities = 56/283 (19%), Positives = 122/283 (43%), Gaps = 33/283 (11%)
Query: 67 EKFAKVENQYQLL--KLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQE 124
E +EN Q L KLE EF+ + + IS I ++ + +++K Q A ++ L E
Sbjct: 1067 ESTMDMENDKQQLDEKLEKKEFE-ISNLISKIEDEQAVEIQLQKKIKELQ--ARIEELGE 1123
Query: 125 EINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISG 184
EI + + +++ L+ L +S+ + + +T++ ++ K + +RR
Sbjct: 1124 EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQV-ELNKKREAEFQKLRR--- 1179
Query: 185 LVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKK 244
L ++ + E + + K ++ +L ID ++ Q++ K
Sbjct: 1180 ------DLEEATLQHEAMVAALRKKHADSMAEL-GEQIDNLQRVK-------QKLEKEKS 1225
Query: 245 TLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTLR 304
L D + + +G+ K+ ++ L+ +V LK + L+NDLT +
Sbjct: 1226 ELKMETDDLSSNAEAISKAKGNLEKMCRS------LEDQVSELKTKEEEQQRLINDLTAQ 1279
Query: 305 IGRLVTDL----LQREKEIAFLSEKISNLTIVQAEIKDIKDEI 343
RL T+ Q +++ A +S+ + +I+++K ++
Sbjct: 1280 RARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQL 1322
>gi|18641360 collectin sub-family member 12 [Homo sapiens]
Length = 742
Score = 48.9 bits (115), Expect = 7e-06
Identities = 47/215 (21%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 135 RITEKQDILNNSLTTLSQD----ITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDVI 190
++ EK D + + T Q +T V+ + G K S +++ S +D++
Sbjct: 60 KVVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSEL---STFRSDIL 116
Query: 191 SLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLTELK 250
L ++E+ K K K+T++ + + +DR + L++T NS I +V KTL
Sbjct: 117 DLRQQLREITEKTSK-NKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYN 175
Query: 251 SDFDKHTDRFLSLEGDRAKVLKT----VTFANDLKPKVYNLKKDFSRLEPLVNDLTLRIG 306
L+G+ + + + N+L + + L+ V+D + I
Sbjct: 176 GYVTNLQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQ 235
Query: 307 RLVTD-------LLQREKEIAFLSEKISNLTIVQA 334
R+ D LQ +K+ +L EK+ +L + A
Sbjct: 236 RIKNDFQNLQQVFLQAKKDTDWLKEKVQSLQTLAA 270
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 48.9 bits (115), Expect = 7e-06
Identities = 58/297 (19%), Positives = 133/297 (44%), Gaps = 36/297 (12%)
Query: 71 KVENQYQLLKLETNEFQ-QLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEINEV 129
++E + L E N+ Q Q+Q++ +++ ++ + +++ Q+ A +K + E + +
Sbjct: 874 ELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKN--KIQLEAKVKEMNERLEDE 931
Query: 130 KTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDV 189
+ + +T K+ L + + L +DI ++ + + K+ VK ++GL +
Sbjct: 932 EEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 991
Query: 190 ISLT--------------DSVQELENKIEKVEKNTVK--NIGDLLSSSIDRTATLRKTAS 233
LT D +Q E+K+ + K+ VK D L S+++ +R
Sbjct: 992 AKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLE 1051
Query: 234 ENSQRINS----VKKTLTELKSD----FDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVY 285
+++ ++++ +L++D +K + + +K+ A L+ K
Sbjct: 1052 RAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKK-- 1109
Query: 286 NLKKDFSRLEPLVNDL------TLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEI 336
LK++ +R+E L +L ++ +L +DL + +EI+ E+ T VQ E+
Sbjct: 1110 -LKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEM 1165
Score = 33.1 bits (74), Expect = 0.38
Identities = 57/278 (20%), Positives = 117/278 (42%), Gaps = 28/278 (10%)
Query: 64 QQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQ-----LKSFQIIAH 118
Q +E K+E + L T + +LQ++ ++ + ++ EA++ Q L Q +
Sbjct: 1257 QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMED 1316
Query: 119 LKRLQEEINEVKTWSNRITEKQ----DILNNSLTTLSQDITKVDQSTTSMAKDVGLKITS 174
LKR EE + K + D+L ++ ++ + + +V T
Sbjct: 1317 LKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1376
Query: 175 VKTD-IRRISGLVTDVISLTDSVQELENKIEKVE---------KNTVKNIGDLLSSSIDR 224
+TD I+R L L +Q+ E +E V K+ ++N + L ++R
Sbjct: 1377 YETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1436
Query: 225 TATLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTF--ANDLKP 282
+ A+ ++ + K L E K +++ S + + A+ L T F N +
Sbjct: 1437 S---NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKE-ARSLSTELFKLKNAYEE 1492
Query: 283 KVYNL---KKDFSRLEPLVNDLTLRIGRLVTDLLQREK 317
+ +L K++ L+ ++DLT ++G ++ + EK
Sbjct: 1493 SLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 47.4 bits (111), Expect = 2e-05
Identities = 61/269 (22%), Positives = 115/269 (42%), Gaps = 24/269 (8%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEI 126
E+ +V+ +Y+ L + +FQ L S+ +SE+ Q + +E S Q A+L+ ++
Sbjct: 1726 EELERVKMEYETL---SKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQ--ANLEATEKHD 1780
Query: 127 NEVKTWSNRI------TEKQDILNNSLT-TLSQDITKVDQSTTSMAKD------VGLKIT 173
N+ TE+QD L+ S T S+ + + +++KD + +
Sbjct: 1781 NQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQ 1840
Query: 174 SVKTDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDL--LSSSIDRTATLRKT 231
+ RI+GL + + Q LEN+ + G+L L + + L +
Sbjct: 1841 QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQ 1900
Query: 232 ASENSQRINSVKKTLTELKSDFDKH-TDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKD 290
E R+ +K+T E K D ++ ++ L G + VT D + K L+ +
Sbjct: 1901 IQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVT---DAQIKNELLESE 1957
Query: 291 FSRLEPLVNDLTLRIGRLVTDLLQREKEI 319
L+ V++L +LV + + E EI
Sbjct: 1958 MKNLKKCVSELEEEKQQLVKEKTKVESEI 1986
Score = 47.0 bits (110), Expect = 3e-05
Identities = 56/285 (19%), Positives = 125/285 (43%), Gaps = 29/285 (10%)
Query: 71 KVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEINEVK 130
K Q QLL+++ + ++L++K + + EK ++SE E L+ LQEE +
Sbjct: 2547 KDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRR-----SFNALQEEKQD-- 2599
Query: 131 TWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDVI 190
++++ + L S++ L++ +T + + T LK+ + ++ R+S L +
Sbjct: 2600 -----LSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVK--EEEVHRLSALFS--- 2649
Query: 191 SLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLTELK 250
S + ELE ++ V+K K +G++ L A + ++ + EL
Sbjct: 2650 SSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELA 2709
Query: 251 SDFDKHTDRFLSL----EGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTLRIG 306
D + + L + +G A++ + L+ + ++ L+ + +
Sbjct: 2710 RDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELA 2769
Query: 307 RLVTD-LLQREKEIAFLSEKISNLTIVQAEIKDIKDEIAHISDMN 350
+L LL RE++ A LSE ++ + ++ ++H+ +N
Sbjct: 2770 QLKEQGLLNRERD-ALLSETAFSMNSTE------ENSLSHLEKLN 2807
Score = 38.5 bits (88), Expect = 0.009
Identities = 61/294 (20%), Positives = 127/294 (43%), Gaps = 26/294 (8%)
Query: 66 SEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQI----IAHLKR 121
SE K E +QL + + +++S ++ E +E++ ++L+S Q+ + HL+
Sbjct: 1330 SELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE 1389
Query: 122 LQEEINEVKTWSNRITEKQDILNNSLTTLSQDITK-----VDQSTTSMAKDVGLKITSVK 176
LQ +++E++ ++ E L+ L+ +TK ++Q A L++ + +
Sbjct: 1390 LQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1449
Query: 177 TDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLS--SSIDRTATLRKTASE 234
D RI L ++ + +E+ + ++ K L+S ++ +L++ S
Sbjct: 1450 HD-ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSL 1508
Query: 235 NSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRL 294
I + K+L +++S ++ VL + + + K+ + D S L
Sbjct: 1509 ARGTIERLTKSLADVESQVSAQNK-------EKDTVLGRLALLQEERDKLIT-EMDRSLL 1560
Query: 295 E-----PLVNDLTLRIGRLVTDLLQREKEIAFL-SEKISNLTIVQAEIKDIKDE 342
E L L + L D + KEI L S KI+ T Q + K+++ E
Sbjct: 1561 ENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKE 1614
Score = 35.0 bits (79), Expect = 0.10
Identities = 60/260 (23%), Positives = 113/260 (43%), Gaps = 37/260 (14%)
Query: 120 KRLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKD---VGLKITSVK 176
K+LQE + K + EK+ L L D ++ + +K+ +G ++ ++
Sbjct: 1178 KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1237
Query: 177 TDIRR-ISGLV--TDVISLTDSVQELENKIEK-VEKNTVKNI------GDLLSSSIDRT- 225
+R I G + TD S LE + K E++ + + D S S D +
Sbjct: 1238 IQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASA 1297
Query: 226 -----------ATLRKTASENSQRINSVKKTLTEL--KSDFDKHTDRFLSLEGDRAKVLK 272
A L++ +E + V T +EL KS+ ++ +G + LK
Sbjct: 1298 LQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLK 1357
Query: 273 TVT-----FANDLKPKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAF----LS 323
TV+ A L+ K+ + + + LE L +L ++ L + ++E+++++ LS
Sbjct: 1358 TVSHEAEVHAESLQQKLESSQLQIAGLEHL-RELQPKLDELQKLISKKEEDVSYLSGQLS 1416
Query: 324 EKISNLTIVQAEIKDIKDEI 343
EK + LT +Q EI + +D I
Sbjct: 1417 EKEAALTKIQTEIIEQEDLI 1436
Score = 34.7 bits (78), Expect = 0.13
Identities = 26/132 (19%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 117 AHLKRLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVK 176
AH L E+I+ + + K ++L N L + ++ S+ + K + V
Sbjct: 789 AHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL 848
Query: 177 TDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENS 236
R+ + + V L+ ++ + E +I K+++ ++ D+ TL++T E
Sbjct: 849 EGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDV--------ETLQQTIEEKD 900
Query: 237 QRINSVKKTLTE 248
Q++ + ++TE
Sbjct: 901 QQVTEISFSMTE 912
Score = 34.3 bits (77), Expect = 0.17
Identities = 50/289 (17%), Positives = 121/289 (41%), Gaps = 47/289 (16%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQE 124
+S+ +V+ Q ++ E ++L S++ + S+ + +L+S LK L++
Sbjct: 2265 ESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLES-----ELKSLKD 2319
Query: 125 EINEVKTWSNRITEKQ------------DILNN--SLTTLSQDITKVDQSTTSMAKDVGL 170
++ ++ + E++ DI N+ S L D+ + T+ + +++ +
Sbjct: 2320 QLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2379
Query: 171 K----ITSVKTDIRRISGLVTDVISLTDS-VQELENKIEKVEKNTVKNIGDLLSSSIDRT 225
K I+ + I + ++ D ++ELEN + + E+ + + + ++D+T
Sbjct: 2380 KEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIV-LEEENKKAVDKT 2438
Query: 226 ATLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAK---------------V 270
L +T + ++KK + K+ D SL+ DR + +
Sbjct: 2439 NQLMET-------LKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSII 2491
Query: 271 LKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEI 319
L+ + + LK++ L ++DL +L +L+Q +++
Sbjct: 2492 LEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDL 2540
Score = 30.4 bits (67), Expect = 2.5
Identities = 46/280 (16%), Positives = 116/280 (41%), Gaps = 37/280 (13%)
Query: 72 VENQYQLLKLETNEFQQLQSKISLISEKWQ-KSEAIMEQLKSFQII-------AHLKRLQ 123
+E++ + LK +E ++ K L+ EK + +SE E L+ Q +H K LQ
Sbjct: 1954 LESEMKNLKKCVSELEE--EKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQ 2011
Query: 124 EEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRIS 183
E + E + ++ + ++ L + + ++ T KD+ + ++ +
Sbjct: 2012 ELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRK 2071
Query: 184 GLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVK 243
++ S + + +++ +V + +K L+K N + SVK
Sbjct: 2072 KAQAELASFKVLLDDTQSEAARVLADNLK---------------LKKELQSNKE---SVK 2113
Query: 244 KTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTL 303
+ + D ++ LE K LK +++ K+ L+++ LE + ++ +
Sbjct: 2114 SQMKQKDEDLERR------LEQAEEKHLKE---KKNMQEKLDALRREKVHLEETIGEIQV 2164
Query: 304 RIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEI 343
+ + ++ Q ++ + +++ T + ++D +D +
Sbjct: 2165 TLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRV 2204
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 47.0 bits (110), Expect = 3e-05
Identities = 51/237 (21%), Positives = 111/237 (46%), Gaps = 27/237 (11%)
Query: 70 AKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQII--AHLKRLQEEIN 127
A+VE + + + E +++Q I + E+ ++ E+ ++L+ ++ A LK+L+EE
Sbjct: 922 ARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQI 981
Query: 128 EVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAK---DVGLKITSVKTDIRRIS- 183
++ + ++ +++ +L + + + ++T+ ++ + S+AK IT ++ +RR
Sbjct: 982 ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEK 1041
Query: 184 ----------GLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTAS 233
L D L+D + EL+ +I +++ K +L A L +
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEEL-------QAALARVEE 1094
Query: 234 ENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKD 290
E +Q+ N K + EL+S + + LE +RA K DL ++ LK +
Sbjct: 1095 EAAQK-NMALKKIRELESQISELQE---DLESERASRNKAEKQKRDLGEELEALKTE 1147
Score = 31.6 bits (70), Expect = 1.1
Identities = 54/280 (19%), Positives = 119/280 (42%), Gaps = 28/280 (10%)
Query: 70 AKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEINEV 129
A +E Q L+ NE +L +++ ++ + SE K ++ A L+ LQ + NE
Sbjct: 1213 ANLEKAKQTLE---NERGELANEVKVLLQGKGDSEH-----KRKKVEAQLQELQVKFNEG 1264
Query: 130 KTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDV 189
+ + +K L L ++ +++ D ++ + KD + ++ +
Sbjct: 1265 ERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQK 1324
Query: 190 ISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLTEL 249
+SL+ ++++E+ EKN+ + + L + L K + ++ +KK + +
Sbjct: 1325 LSLSTKLKQVED-----EKNSFR---EQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDS 1376
Query: 250 KSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYN-LKKDFSRLEPLVNDLTLRIGRL 308
+ + L+ D L+ ++ ++ K Y+ L+K +RL+ ++D L
Sbjct: 1377 VGCLETAEEVKRKLQKD----LEGLSQRHEEKVAAYDKLEKTKTRLQQELDD-------L 1425
Query: 309 VTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEIAHISD 348
+ DL + + L +K + AE K I + A D
Sbjct: 1426 LVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERD 1465
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 47.0 bits (110), Expect = 3e-05
Identities = 74/344 (21%), Positives = 143/344 (41%), Gaps = 73/344 (21%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQL---------------------QSKISLISEKWQKS 103
+ E+ ++N LLK E + Q L KI L+ E+ Q
Sbjct: 633 KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQ-- 690
Query: 104 EAIMEQLKSFQII-AHLKRLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTT 162
I +++ F+I+ K L+ E+ +++T + K D++ + + I + D+
Sbjct: 691 HEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNK-DVVEQ----MEKCIQEKDEKLK 745
Query: 163 SMAKDVGLKITSVKTDIRRISGLVTDVISLTDSVQELENK----------IEKVEK---- 208
++ + + + V T ++ + T+ SLT VQ+L+ K +E+++K
Sbjct: 746 TVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHE 805
Query: 209 --NTVKNIGDLLSSSIDRTATLRKTA---------------SENSQRINSVKKTLTELKS 251
+K++ +LL + + + A KT +++N++K L E +
Sbjct: 806 KDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEK 865
Query: 252 DFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKK-----DFSRLEPLVNDLTLRIG 306
D +T ++L + + LK A+ + +NLK+ F LE ++ + +
Sbjct: 866 DL-ANTGKWLQDLQEENESLK----AHVQEVAQHNLKEASSASQFEELEIVLKEKENELK 920
Query: 307 RLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEIAHISDMN 350
RL L +RE + LS K L VQ E K K +I + N
Sbjct: 921 RLEAMLKERESD---LSSKTQLLQDVQDENKLFKSQIEQLKQQN 961
Score = 38.1 bits (87), Expect = 0.012
Identities = 46/205 (22%), Positives = 88/205 (42%), Gaps = 23/205 (11%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEI 126
EK + N + L+ E + L++ + +++ K + Q + +I+ L+E+
Sbjct: 862 EKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIV-----LKEKE 916
Query: 127 NEVKTWSNRITEKQDILNNSLTTLS--QDITKVDQSTTSMAKDVG-------------LK 171
NE+K + E++ L++ L QD K+ +S K LK
Sbjct: 917 NELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLK 976
Query: 172 ITSVKTDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKT 231
+ S + + ISGL ++ SL D+V+ K + + + + L S+ + KT
Sbjct: 977 VISERE--KEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKT 1034
Query: 232 ASENSQRINSVKKTLTE-LKSDFDK 255
+ E Q++ +V+ E LK F K
Sbjct: 1035 SKERQQQVEAVELEAKEVLKKLFPK 1059
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 47.0 bits (110), Expect = 3e-05
Identities = 57/297 (19%), Positives = 131/297 (44%), Gaps = 36/297 (12%)
Query: 71 KVENQYQLLKLETNEFQ-QLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEINEV 129
++E + L E N+ Q Q+Q++ +++ ++ + +++ Q+ A +K + E + +
Sbjct: 872 ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN--KIQLEAKVKEMNERLEDE 929
Query: 130 KTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDV 189
+ + +T K+ L + + L +DI ++ + + K+ VK ++GL +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 190 ISLT--------------DSVQELENKIEKVEKNTVK--NIGDLLSSSIDRTATLRKTAS 233
LT D +Q E+K+ + K VK D L S+++ +R
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLE 1049
Query: 234 ENSQRINS----VKKTLTELKSDFDKHTDRF----LSLEGDRAKVLKTVTFANDLKPKVY 285
+++ ++++ +L++D + +R L A++ + L+ K+
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109
Query: 286 NLKKDFSRLEPLVNDL------TLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEI 336
L+ +R+E L +L ++ +L +DL + +EI+ E+ T VQ E+
Sbjct: 1110 ELQ---ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEM 1163
Score = 40.0 bits (92), Expect = 0.003
Identities = 50/264 (18%), Positives = 118/264 (44%), Gaps = 20/264 (7%)
Query: 89 LQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEINEVKTWSNRITEKQDILNNSLT 148
L+ I+++ + +A +E+L++ R E ++T +E+ +L++ T
Sbjct: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIET-----SERVQLLHSQNT 1721
Query: 149 TLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDVISLTDSV---QELENKIEK 205
+L K+D + + +V + + + +TD + + + Q+ +E+
Sbjct: 1722 SLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1781
Query: 206 VEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINS-VKKTLTELKSDFDKHTDRFLSLE 264
++KN + I DL + K + Q++ + V++ EL+++ ++ + S++
Sbjct: 1782 MKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAE---SVK 1838
Query: 265 GDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAFLSE 324
G R K+ +L + +K+ RL+ LV+ L L++ + E++ +
Sbjct: 1839 GMR----KSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQ---ANT 1891
Query: 325 KISNLTIVQAEIKDIKDEIAHISD 348
+S VQ E+ D +E A I++
Sbjct: 1892 NLSKFRKVQHEL-DEAEERADIAE 1914
>gi|14165274 golgi-associated microtubule-binding protein HOOK3
[Homo sapiens]
Length = 718
Score = 46.6 bits (109), Expect = 3e-05
Identities = 63/301 (20%), Positives = 129/301 (42%), Gaps = 48/301 (15%)
Query: 66 SEKFAKVENQYQLLKLETNEFQQLQSKISLISEK--------------WQKSEAIMEQLK 111
S+K +K+E Q + K + + L+ ++ L+ EK +K+ A QL+
Sbjct: 310 SDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLE 369
Query: 112 SF--QIIA-----------------HLKRLQEEINEVKTWSNRITEKQDILNNSLTTLSQ 152
++ Q++ KRL+E+++ ++ +R+ ++D L ++ L
Sbjct: 370 TYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRC 429
Query: 153 DITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVK 212
+ Q TT +G S ++ + +VT I + ENK+ K+ +
Sbjct: 430 VQAQEGQLTTQGLMPLG----SQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSD 485
Query: 213 NIGDLLSSSIDRTATLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRA---- 268
N L S+ A LRK E R+ V + L E++S ++ + L +G +A
Sbjct: 486 NEKIALLQSLLDDANLRKNELETENRL--VNQRLLEVQSQVEE-LQKSLQDQGSKAEDSV 542
Query: 269 ----KVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAFLSE 324
K+ + + ++ ++ + LEP N+ +L+I L L ++E+E+ + E
Sbjct: 543 LLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEE 602
Query: 325 K 325
+
Sbjct: 603 R 603
Score = 30.4 bits (67), Expect = 2.5
Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 10/72 (13%)
Query: 280 LKPKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDI 339
L+ ++ L+++ RLE +D +R L EKEI+ L ++ LT + E + +
Sbjct: 247 LQTQLEQLQEETFRLEAAKDDYRIRCEEL-------EKEISELRQQNDELTTLADEAQSL 299
Query: 340 KDEI---AHISD 348
KDEI H SD
Sbjct: 300 KDEIDVLRHSSD 311
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 46.6 bits (109), Expect = 3e-05
Identities = 54/293 (18%), Positives = 132/293 (45%), Gaps = 25/293 (8%)
Query: 68 KFAKVENQYQLLKLETNEFQ-QLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEI 126
K ++E + L E N+ Q Q+Q++ +++ ++ + +++ Q+ A +K + E
Sbjct: 873 KRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKT--KIQLEAKIKEVTERA 930
Query: 127 NEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLV 186
+ + + +T K+ L + + L +DI ++ + + K+ VK ++GL
Sbjct: 931 EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 990
Query: 187 TDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTL 246
+ LT + +++ + T+ D L D+ TL K ++ Q+++ ++ +L
Sbjct: 991 ETIAKLTKE----KKALQEAHQQTL----DDLQMEEDKVNTLTKAKTKLEQQVDDLEGSL 1042
Query: 247 TELKS---DFDKHTDRFLSLEGD----RAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVN 299
+ K D ++ + LEGD + + T L K+ + + S L+ +
Sbjct: 1043 EQEKKLCMDLERAKRK---LEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIE 1099
Query: 300 D---LTLRIGRLVTDLLQREKEI-AFLSEKISNLTIVQAEIKDIKDEIAHISD 348
D L +++ + + +L R +E+ + + ++ + + D+ E+ IS+
Sbjct: 1100 DEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1152
Score = 40.0 bits (92), Expect = 0.003
Identities = 47/226 (20%), Positives = 100/226 (44%), Gaps = 31/226 (13%)
Query: 67 EKFAKVENQYQLL--KLETNEFQQ--LQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRL 122
E EN Q L KL+ EF+ LQ KI + +++ AI Q K ++ A ++ L
Sbjct: 1068 ESTMDTENDKQQLNEKLKKKEFEMSNLQGKI-----EDEQALAIQLQKKIKELQARIEEL 1122
Query: 123 QEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTS---MAKDVGLKITSVKTDI 179
+EEI + + +++ L+ L +S+ + + +T++ M K + ++ D+
Sbjct: 1123 EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDL 1182
Query: 180 ---------------RRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDR 224
++ + V ++ DS+Q ++ K+EK + I DL S+
Sbjct: 1183 EESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASN---- 1238
Query: 225 TATLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKV 270
T+ K + + +++ L+E+K+ ++ L +A++
Sbjct: 1239 METVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARL 1284
Score = 34.7 bits (78), Expect = 0.13
Identities = 46/200 (23%), Positives = 78/200 (39%), Gaps = 13/200 (6%)
Query: 110 LKSFQIIAHLKRLQEEINEVKTWSNRITEKQDILNNSLTTLSQ---DITKVDQSTTSMAK 166
LKS + + ++EE + K + K+ L + TL Q D+ Q+
Sbjct: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALA 903
Query: 167 DVGLKITS-VKTDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRT 225
D + +KT I ++ + +V + +E+ ++ ++ +L D
Sbjct: 904 DAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 226 ATLRKTASENSQRINSVKKTLTELKSDFD----KHTDRFLSLEGDRAKVLKTVTFANDLK 281
TL K E N V K LTE + D K T +L+ + L + D
Sbjct: 963 LTLAKVEKEKHATENKV-KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEED-- 1019
Query: 282 PKVYNLKKDFSRLEPLVNDL 301
KV L K ++LE V+DL
Sbjct: 1020 -KVNTLTKAKTKLEQQVDDL 1038
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 45.8 bits (107), Expect = 6e-05
Identities = 56/293 (19%), Positives = 135/293 (46%), Gaps = 25/293 (8%)
Query: 68 KFAKVENQYQLLKLETNEFQ-QLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEI 126
K ++E + L E N+ Q Q+Q++ +++ ++ + +++ Q+ A +K + E
Sbjct: 873 KRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKT--KIQLEAKIKEVTERA 930
Query: 127 NEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLV 186
+ + + +T K+ L + + L +DI ++ + + K+ VK ++GL
Sbjct: 931 EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 990
Query: 187 TDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTL 246
+ LT + +++ + T+ D L + D+ TL K + Q+++ ++ +L
Sbjct: 991 ETIAKLTKE----KKALQEAHQQTL----DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1042
Query: 247 TE---LKSDFDKHTDRFLSLEGD-RAKVLKTVTFANDLKPKVYNLKK---DFSRLEPLVN 299
+ ++ D ++ + LEGD + T+ ND + LKK + S L+ +
Sbjct: 1043 EQEKKIRMDLERAKRK---LEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIE 1099
Query: 300 D---LTLRIGRLVTDLLQREKEI-AFLSEKISNLTIVQAEIKDIKDEIAHISD 348
D L +++ + + +L R +E+ + + ++ + + D+ E+ IS+
Sbjct: 1100 DEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1152
Score = 45.4 bits (106), Expect = 7e-05
Identities = 55/277 (19%), Positives = 104/277 (37%), Gaps = 42/277 (15%)
Query: 96 ISEKWQKSEAIMEQLKSFQIIAHLKRLQEEINEVKTWSNRITEKQDILNNSLTTLSQDIT 155
+ + + E + EQL + A+L LQ EI E++ + + I L S+ +
Sbjct: 1661 LDDALRSQEDLKEQLAMVERRANL--LQAEIEELRATLEQTERSRKIAEQELLDASERVQ 1718
Query: 156 KVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDVI------------SLTDSV------- 196
+ TS+ ++TDI +I G + D+I ++TD+
Sbjct: 1719 LLHTQNTSLINTK----KKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELK 1774
Query: 197 --QELENKIEKVEKNTVKNIGDL-----------LSSSIDRTATLRKTASENSQRINSVK 243
Q+ +E+++KN + + DL L + L E + S +
Sbjct: 1775 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1834
Query: 244 KTLTELKSDFDKHTDRFLSL----EGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVN 299
K E KH + L E DR +L+ + L+ KV + K+ E N
Sbjct: 1835 KRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1894
Query: 300 DLTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEI 336
+ R+ +L + E+ +++ L + E+
Sbjct: 1895 VNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREV 1931
Score = 39.3 bits (90), Expect = 0.005
Identities = 51/274 (18%), Positives = 112/274 (40%), Gaps = 18/274 (6%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQE 124
+ EK +++ + KLE + +S + + ++K Q E + + K F+ + LQ
Sbjct: 1043 EQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKK--KEFE----MSGLQS 1096
Query: 125 EINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISG 184
+I + + ++ +K L + L ++I S K + + + ++ IS
Sbjct: 1097 KIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEK----QRSDLSRELEEISE 1152
Query: 185 LVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKK 244
+ + T + E+ K E + +++ + ATLRK +++ +
Sbjct: 1153 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID 1212
Query: 245 TLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFAND--------LKPKVYNLKKDFSRLEP 296
L +K +K D A ++TV+ A L+ ++ +K +
Sbjct: 1213 NLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQR 1272
Query: 297 LVNDLTLRIGRLVTDLLQREKEIAFLSEKISNLT 330
L+NDLT + RL T+ + +++ +S L+
Sbjct: 1273 LINDLTAQRARLQTESGEYSRQLDEKDTLVSQLS 1306
Score = 35.0 bits (79), Expect = 0.10
Identities = 55/246 (22%), Positives = 95/246 (38%), Gaps = 26/246 (10%)
Query: 110 LKSFQIIAHLKRLQEEINEVKTWSNRITEKQDILNNSLTTLSQDIT----KVDQSTTSMA 165
LKS + + ++EE + K + K+ L + TL Q+ +V S+A
Sbjct: 844 LKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLA 903
Query: 166 KDVGLKITSVKTDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRT 225
+KT I ++ + +V + +E+ ++ ++ +L D
Sbjct: 904 DAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 226 ATLRKTASENSQRINSVKKTLTELKSDFD----KHTDRFLSLEGDRAKVLKTVTFANDLK 281
TL K E N V K LTE + D K T +L+ + L + D
Sbjct: 963 LTLAKVEKEKHATENKV-KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED-- 1019
Query: 282 PKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAFLSEKI-----SNLTIVQAEI 336
KV L K +LE V+DL L++EK+I E+ +L + Q
Sbjct: 1020 -KVNTLTKAKIKLEQQVDDL--------EGSLEQEKKIRMDLERAKRKLEGDLKLAQEST 1070
Query: 337 KDIKDE 342
DI+++
Sbjct: 1071 MDIEND 1076
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 45.8 bits (107), Expect = 6e-05
Identities = 73/305 (23%), Positives = 130/305 (42%), Gaps = 51/305 (16%)
Query: 82 ETNEFQQLQSKISLISEKWQKSEAIME--QLKSFQIIA---HLKRLQEEINEVKTWSNRI 136
E N S I I W++ + I++ KS QI +++LQ E+ K +NR+
Sbjct: 1006 EPNRENSFHSSIEAI---WEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRL 1062
Query: 137 TEK----QDILNNSLTTLSQDITKVDQSTTSMAKDVGLK---------------ITSVKT 177
EK QD L TL Q + K + ++ DV ++ +T K
Sbjct: 1063 KEKEHKNQDDLLKEKETLIQQL-KEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKA 1121
Query: 178 DIRRISGLV-------TDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLR- 229
I+ + ++ + L + E E+ I K+E+N +K + L S+ T L
Sbjct: 1122 KIKELETILETQKVECSHSAKLEQDILEKESIILKLERN-LKEFQEHLQDSVKNTKDLNV 1180
Query: 230 ---KTASENSQRINSVK--KTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKV 284
K E +Q N+++ K L +LK + ++ T+R + LK A+ + +
Sbjct: 1181 KELKLKEEITQLTNNLQDMKHLLQLKEE-EEETNR------QETEKLKEELSASSARTQ- 1232
Query: 285 YNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEIA 344
NLK D R E DL ++ + Q +KE++ + ++ L I E++ K++ +
Sbjct: 1233 -NLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCS 1291
Query: 345 HISDM 349
DM
Sbjct: 1292 QELDM 1296
Score = 28.9 bits (63), Expect = 7.2
Identities = 55/286 (19%), Positives = 121/286 (42%), Gaps = 29/286 (10%)
Query: 72 VENQYQLLKLETNEFQQ----LQSKISLISEKWQKSEAIMEQLKSFQIIA----HLKRL- 122
+EN+ + K E E + Q ++SL +K ++Q++S IA H+++
Sbjct: 854 IENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSK 913
Query: 123 -QEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQ-------STTSMAKDVGLKITS 174
QE+ ++ SN I + N+++ + TK+D+ S S + L+ S
Sbjct: 914 NQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLS 973
Query: 175 VKTDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASE 234
++ + D++ V + + E N + + + + + K +S+
Sbjct: 974 NGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSK 1033
Query: 235 NSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRL 294
S +I +++ + +L+++ + D E +R K K +DL LK+ + +
Sbjct: 1034 KSHQIEELEQQIEKLQAEVKGYKD-----ENNRLKE-KEHKNQDDL------LKEKETLI 1081
Query: 295 EPLVNDLTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIK 340
+ L +L + L + + LSE +T +A+IK+++
Sbjct: 1082 QQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELE 1127
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 [Homo
sapiens]
Length = 1288
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/294 (18%), Positives = 132/294 (44%), Gaps = 37/294 (12%)
Query: 78 LLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQI-IAHLKRLQEEINEVKTWS-NR 135
++++ E +++S++ S+K + + QL+ + + H +R E T S R
Sbjct: 768 VIEISEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQR 827
Query: 136 ITEKQDILNNSLTTLSQDI--TKVDQSTTSMAKD-----------VGLKITSVKTDIRRI 182
+ E+++ LN + L ++ T D+ + ++ V K V+ +++R+
Sbjct: 828 LIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRL 887
Query: 183 SGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRI-NS 241
+ ++ + ++ ++K++K+ K D +S+I + KTA N Q+ +S
Sbjct: 888 HNTIVEINN--HKLKAQQDKLDKINKQL-----DECASAITKAQVAIKTADRNLQKAQDS 940
Query: 242 VKKTLTELKS---DFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYN-----------L 287
V +T E+K + D T SLE A+V+K A + P++ +
Sbjct: 941 VLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVI 1000
Query: 288 KKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKD 341
+++ L+ + L++ ++ + + +I + ++IS +++ E I++
Sbjct: 1001 QENEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEE 1054
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 [Homo
sapiens]
Length = 1288
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/294 (18%), Positives = 132/294 (44%), Gaps = 37/294 (12%)
Query: 78 LLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQI-IAHLKRLQEEINEVKTWS-NR 135
++++ E +++S++ S+K + + QL+ + + H +R E T S R
Sbjct: 768 VIEISEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQR 827
Query: 136 ITEKQDILNNSLTTLSQDI--TKVDQSTTSMAKD-----------VGLKITSVKTDIRRI 182
+ E+++ LN + L ++ T D+ + ++ V K V+ +++R+
Sbjct: 828 LIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRL 887
Query: 183 SGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRI-NS 241
+ ++ + ++ ++K++K+ K D +S+I + KTA N Q+ +S
Sbjct: 888 HNTIVEINN--HKLKAQQDKLDKINKQL-----DECASAITKAQVAIKTADRNLQKAQDS 940
Query: 242 VKKTLTELKS---DFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYN-----------L 287
V +T E+K + D T SLE A+V+K A + P++ +
Sbjct: 941 VLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQELKVI 1000
Query: 288 KKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKD 341
+++ L+ + L++ ++ + + +I + ++IS +++ E I++
Sbjct: 1001 QENEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEE 1054
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 45.4 bits (106), Expect = 7e-05
Identities = 56/294 (19%), Positives = 136/294 (46%), Gaps = 34/294 (11%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKS--FQIIAHLKRLQEEINEVK 130
++Q + K E ++L+ K+S + +K + S ++LK+ + + K EEI ++
Sbjct: 942 QSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEI--LQ 999
Query: 131 TWSNRITEKQDIL------NNSLTTLSQDITK-VDQSTTSMAKDVGLKITSVKTDIRRIS 183
+ + +D L N+ L +++ K D++ + + ++I T +
Sbjct: 1000 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK--- 1056
Query: 184 GLVTDVISLTDSVQ---ELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRIN 240
+ SL D+ Q +L+N+++ +++N +KN+ +L S ++ + +Q++
Sbjct: 1057 --TETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKS--------KELLTVENQKME 1106
Query: 241 SVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVND 300
+K + LK + + + +L+ + K+ + + + D L+++ S L + +
Sbjct: 1107 EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLE 1166
Query: 301 LTLRIGRLVTDLLQREKEIAFLSEKIS----NLTIVQAEIKDIKDEIAHISDMN 350
+ R + + D ++E A L + IS LT AE++ +++E+ + N
Sbjct: 1167 MKKRESKFIKD---ADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGEN 1217
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 45.4 bits (106), Expect = 7e-05
Identities = 56/294 (19%), Positives = 136/294 (46%), Gaps = 34/294 (11%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKS--FQIIAHLKRLQEEINEVK 130
++Q + K E ++L+ K+S + +K + S ++LK+ + + K EEI ++
Sbjct: 977 QSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEI--LQ 1034
Query: 131 TWSNRITEKQDIL------NNSLTTLSQDITK-VDQSTTSMAKDVGLKITSVKTDIRRIS 183
+ + +D L N+ L +++ K D++ + + ++I T +
Sbjct: 1035 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK--- 1091
Query: 184 GLVTDVISLTDSVQ---ELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRIN 240
+ SL D+ Q +L+N+++ +++N +KN+ +L S ++ + +Q++
Sbjct: 1092 --TETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKS--------KELLTVENQKME 1141
Query: 241 SVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVND 300
+K + LK + + + +L+ + K+ + + + D L+++ S L + +
Sbjct: 1142 EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLE 1201
Query: 301 LTLRIGRLVTDLLQREKEIAFLSEKIS----NLTIVQAEIKDIKDEIAHISDMN 350
+ R + + D ++E A L + IS LT AE++ +++E+ + N
Sbjct: 1202 MKKRESKFIKD---ADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGEN 1252
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 45.1 bits (105), Expect = 1e-04
Identities = 53/269 (19%), Positives = 122/269 (45%), Gaps = 18/269 (6%)
Query: 84 NEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEINEVKTWSNRITEKQDIL 143
N +Q+++ ++ S EA+ ++ ++ + ++LQ +++ +++ + IL
Sbjct: 1502 NLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVIL 1561
Query: 144 NNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDVISLTDSVQELENKI 203
+S + DI + + M + + + TD++ + +V + + + Q K
Sbjct: 1562 QHS----AADIARAE-----MLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKA 1612
Query: 204 EKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSL 263
K ++ +LL+S TA +T SQRI+ +++ + ELK +++ +
Sbjct: 1613 IKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYI 1672
Query: 264 EGDRAKVLKTV-TFANDLKPKV-YNLKKDFSRLEPLVNDLTLRI--GRLVTDLLQREKEI 319
E KV+ TV A D+K + L + + ++E L+ T R ++LQ E +
Sbjct: 1673 E----KVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAK- 1727
Query: 320 AFLSEKISNLTIVQAEIKDIKDEIAHISD 348
L++ S L +++ + +D ++ D
Sbjct: 1728 TLLAQANSKLQLLKDLERKYEDNQRYLED 1756
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 45.1 bits (105), Expect = 1e-04
Identities = 57/287 (19%), Positives = 121/287 (42%), Gaps = 44/287 (15%)
Query: 66 SEKFAKVENQYQLLKLETNEFQQLQSKISLISEKW-----------QKSEA---IMEQLK 111
+EK +V+NQ+ + QQ + + S +W +K EA I++Q +
Sbjct: 2307 TEKLERVKNQWDGTQHGVELRQQQLEDMIIDSLQWDDHREETEELMRKYEARLYILQQAR 2366
Query: 112 SFQIIAHLKRLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLK 171
+ + Q + E+ + ++L L D T+ + TT K +
Sbjct: 2367 RDPLTKQISDNQILLQELGPGDGIVMAFDNVLQKLLEEYGSDDTRNVKETTEYLKTSWIN 2426
Query: 172 ITSVKTDIRRISGLVTDVISLTDSVQELENKIEKVEK--NTVKNIGDLLSSSIDRTATLR 229
+ D R + L + ++ S ++LEN ++ +++ TV + D A+ R
Sbjct: 2427 LKQSIAD--RQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVD---------ASHR 2475
Query: 230 KTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFA------------ 277
+ A ++S +K+ + +++++ D H D F S++G+R K++K + +
Sbjct: 2476 ENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHRLDD 2535
Query: 278 -----NDLKPKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEI 319
NDLK K +++ N L + + L+ L +++E+
Sbjct: 2536 MNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEEL 2582
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.1 bits (105), Expect = 1e-04
Identities = 61/289 (21%), Positives = 130/289 (44%), Gaps = 45/289 (15%)
Query: 67 EKFAKVENQYQLL--KLETNEFQ--QLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRL 122
E +EN+ Q L KL+ EF+ LQSKI + +++ I Q K ++ A ++ L
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKI-----EDEQALGIQLQKKIKELQARIEEL 1124
Query: 123 QEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRI 182
+EEI + + +++ L+ L +S+ + + +T++ ++ K + +RR
Sbjct: 1125 EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI-EMNKKREAEFQKMRR- 1182
Query: 183 SGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINS- 241
D+ T + + K ++V +G+ + +N QR+
Sbjct: 1183 -----DLEEATLQHEATAATLRKKHADSVAELGEQI---------------DNLQRVKQK 1222
Query: 242 VKKTLTELKSDFD---KHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLV 298
++K +E+K + D + + +G+ K+ +T L+ ++ LK + L+
Sbjct: 1223 LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRT------LEDQLSELKSKEEEQQRLI 1276
Query: 299 NDLTLRIGRLVTD----LLQREKEIAFLSEKISNLTIVQAEIKDIKDEI 343
NDLT + GRL T+ Q +++ A +S+ +I+++K ++
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL 1325
Score = 44.3 bits (103), Expect = 2e-04
Identities = 54/280 (19%), Positives = 127/280 (45%), Gaps = 30/280 (10%)
Query: 68 KFAKVENQYQLLKLETNEFQ-QLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEI 126
K ++E + L E N+ Q Q+Q++ +++ ++ + +++ Q+ A +K + E
Sbjct: 875 KRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKT--KIQLEAKIKEVTERA 932
Query: 127 NEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLV 186
+ + + +T K+ L + + L +DI ++ + + K+ VK ++GL
Sbjct: 933 EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 992
Query: 187 TDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTL 246
+ LT + +++ + T+ D L + D+ TL K + Q+++ ++ +L
Sbjct: 993 ETIAKLTKE----KKALQEAHQQTL----DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1044
Query: 247 TE---LKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTL 303
+ L+ D ++ + LEGD LK + + +++ + +L+ +
Sbjct: 1045 EQEKKLRMDLERAKRK---LEGD----LKLA------QESIMDIENEKQQLDEKLKKKEF 1091
Query: 304 RIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEI 343
I L + + + L +KI L QA I+++++EI
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKEL---QARIEELEEEI 1128
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.1 bits (105), Expect = 1e-04
Identities = 61/289 (21%), Positives = 130/289 (44%), Gaps = 45/289 (15%)
Query: 67 EKFAKVENQYQLL--KLETNEFQ--QLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRL 122
E +EN+ Q L KL+ EF+ LQSKI + +++ I Q K ++ A ++ L
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKI-----EDEQALGIQLQKKIKELQARIEEL 1124
Query: 123 QEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRI 182
+EEI + + +++ L+ L +S+ + + +T++ ++ K + +RR
Sbjct: 1125 EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI-EMNKKREAEFQKMRR- 1182
Query: 183 SGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINS- 241
D+ T + + K ++V +G+ + +N QR+
Sbjct: 1183 -----DLEEATLQHEATAATLRKKHADSVAELGEQI---------------DNLQRVKQK 1222
Query: 242 VKKTLTELKSDFD---KHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLV 298
++K +E+K + D + + +G+ K+ +T L+ ++ LK + L+
Sbjct: 1223 LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRT------LEDQLSELKSKEEEQQRLI 1276
Query: 299 NDLTLRIGRLVTD----LLQREKEIAFLSEKISNLTIVQAEIKDIKDEI 343
NDLT + GRL T+ Q +++ A +S+ +I+++K ++
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL 1325
Score = 44.3 bits (103), Expect = 2e-04
Identities = 54/280 (19%), Positives = 127/280 (45%), Gaps = 30/280 (10%)
Query: 68 KFAKVENQYQLLKLETNEFQ-QLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEI 126
K ++E + L E N+ Q Q+Q++ +++ ++ + +++ Q+ A +K + E
Sbjct: 875 KRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKT--KIQLEAKIKEVTERA 932
Query: 127 NEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLV 186
+ + + +T K+ L + + L +DI ++ + + K+ VK ++GL
Sbjct: 933 EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 992
Query: 187 TDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTL 246
+ LT + +++ + T+ D L + D+ TL K + Q+++ ++ +L
Sbjct: 993 ETIAKLTKE----KKALQEAHQQTL----DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1044
Query: 247 TE---LKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTL 303
+ L+ D ++ + LEGD LK + + +++ + +L+ +
Sbjct: 1045 EQEKKLRMDLERAKRK---LEGD----LKLA------QESIMDIENEKQQLDEKLKKKEF 1091
Query: 304 RIGRLVTDLLQREKEIAFLSEKISNLTIVQAEIKDIKDEI 343
I L + + + L +KI L QA I+++++EI
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKEL---QARIEELEEEI 1128
>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
sapiens]
Length = 987
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/249 (22%), Positives = 111/249 (44%), Gaps = 28/249 (11%)
Query: 65 QSEKFAKVENQY--QLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRL 122
+ EK ++ Q L K+E ++ Q + +I +++E + E L ++ H +
Sbjct: 399 EREKLLNIQQQLTCSLRKVE----EENQGALEMIKRLKEENEKLNEFL---ELERHNNNM 451
Query: 123 QEE-INEVKTWSNRITEKQDILNNSLTTLSQDITK---VDQSTTSMAKDVGLKITSVKTD 178
+ + E + + + L + L Q T+ V+Q+ S LK+ + D
Sbjct: 452 MAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKD 511
Query: 179 IRRIS--GLVTDVISLTDSVQELENKIEKVEKNT--VKNIGDLLSSSIDRTAT-LRKTAS 233
+ +S L +++ ++ + + + KVEK+ +K I D + + RT+ L++ AS
Sbjct: 512 LLELSCNELRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEKAS 571
Query: 234 ENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSR 293
E+ I +K+T+ EL+ ++H RA L ++L+ V L++ S
Sbjct: 572 ESDAEIKDMKETIFELEDQVEQH----------RAVKLHNNQLISELESSVIKLEEQKSD 621
Query: 294 LEPLVNDLT 302
LE + LT
Sbjct: 622 LERQLKTLT 630
>gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo
sapiens]
Length = 709
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/249 (22%), Positives = 111/249 (44%), Gaps = 28/249 (11%)
Query: 65 QSEKFAKVENQY--QLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRL 122
+ EK ++ Q L K+E ++ Q + +I +++E + E L ++ H +
Sbjct: 399 EREKLLNIQQQLTCSLRKVE----EENQGALEMIKRLKEENEKLNEFL---ELERHNNNM 451
Query: 123 QEE-INEVKTWSNRITEKQDILNNSLTTLSQDITK---VDQSTTSMAKDVGLKITSVKTD 178
+ + E + + + L + L Q T+ V+Q+ S LK+ + D
Sbjct: 452 MAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKD 511
Query: 179 IRRIS--GLVTDVISLTDSVQELENKIEKVEKNT--VKNIGDLLSSSIDRTAT-LRKTAS 233
+ +S L +++ ++ + + + KVEK+ +K I D + + RT+ L++ AS
Sbjct: 512 LLELSCNELRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEKAS 571
Query: 234 ENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSR 293
E+ I +K+T+ EL+ ++H RA L ++L+ V L++ S
Sbjct: 572 ESDAEIKDMKETIFELEDQVEQH----------RAVKLHNNQLISELESSVIKLEEQKSD 621
Query: 294 LEPLVNDLT 302
LE + LT
Sbjct: 622 LERQLKTLT 630
>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
sapiens]
Length = 1068
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/249 (22%), Positives = 111/249 (44%), Gaps = 28/249 (11%)
Query: 65 QSEKFAKVENQY--QLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRL 122
+ EK ++ Q L K+E ++ Q + +I +++E + E L ++ H +
Sbjct: 480 EREKLLNIQQQLTCSLRKVE----EENQGALEMIKRLKEENEKLNEFL---ELERHNNNM 532
Query: 123 QEE-INEVKTWSNRITEKQDILNNSLTTLSQDITK---VDQSTTSMAKDVGLKITSVKTD 178
+ + E + + + L + L Q T+ V+Q+ S LK+ + D
Sbjct: 533 MAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKD 592
Query: 179 IRRIS--GLVTDVISLTDSVQELENKIEKVEKNT--VKNIGDLLSSSIDRTAT-LRKTAS 233
+ +S L +++ ++ + + + KVEK+ +K I D + + RT+ L++ AS
Sbjct: 593 LLELSCNELRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEKAS 652
Query: 234 ENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSR 293
E+ I +K+T+ EL+ ++H RA L ++L+ V L++ S
Sbjct: 653 ESDAEIKDMKETIFELEDQVEQH----------RAVKLHNNQLISELESSVIKLEEQKSD 702
Query: 294 LEPLVNDLT 302
LE + LT
Sbjct: 703 LERQLKTLT 711
>gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo
sapiens]
Length = 790
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/249 (22%), Positives = 111/249 (44%), Gaps = 28/249 (11%)
Query: 65 QSEKFAKVENQY--QLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRL 122
+ EK ++ Q L K+E ++ Q + +I +++E + E L ++ H +
Sbjct: 480 EREKLLNIQQQLTCSLRKVE----EENQGALEMIKRLKEENEKLNEFL---ELERHNNNM 532
Query: 123 QEE-INEVKTWSNRITEKQDILNNSLTTLSQDITK---VDQSTTSMAKDVGLKITSVKTD 178
+ + E + + + L + L Q T+ V+Q+ S LK+ + D
Sbjct: 533 MAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKD 592
Query: 179 IRRIS--GLVTDVISLTDSVQELENKIEKVEKNT--VKNIGDLLSSSIDRTAT-LRKTAS 233
+ +S L +++ ++ + + + KVEK+ +K I D + + RT+ L++ AS
Sbjct: 593 LLELSCNELRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEKAS 652
Query: 234 ENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSR 293
E+ I +K+T+ EL+ ++H RA L ++L+ V L++ S
Sbjct: 653 ESDAEIKDMKETIFELEDQVEQH----------RAVKLHNNQLISELESSVIKLEEQKSD 702
Query: 294 LEPLVNDLT 302
LE + LT
Sbjct: 703 LERQLKTLT 711
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 44.7 bits (104), Expect = 1e-04
Identities = 64/261 (24%), Positives = 113/261 (43%), Gaps = 38/261 (14%)
Query: 90 QSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEE-INEVKTWSNRITEKQDILNNSLT 148
QS+I + + +K + EQ + F+I L QE +NE + + E + LNN L
Sbjct: 33 QSEIDGLKGRHEKFKVESEQ-QYFEIEKRLSHSQERLVNETRECQSLRLELEK-LNNQLK 90
Query: 149 TLS---------QDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDVIS-LTDSVQE 198
L+ QD QS + K+ ++ + K D+ R + ++ + LT+ V+
Sbjct: 91 ALTEKNKELEIAQDRNIAIQSQFTRTKE---ELEAEKRDLIRTNERLSQELEYLTEDVKR 147
Query: 199 LENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTL----TELKSDFD 254
L K++ E NT K L +D + +R+ K+ L T L ++
Sbjct: 148 LNEKLK--ESNTTKGE---LQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELK 202
Query: 255 KHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTL-------RIGR 307
TD L+L ++ + +LK + N K++ SRLE +N L +
Sbjct: 203 TKTDELLALGREKGNEIL------ELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVED 256
Query: 308 LVTDLLQREKEIAFLSEKISN 328
L+T L + +++ A + EK N
Sbjct: 257 LLTKLKEAKEQQASMEEKFHN 277
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/271 (21%), Positives = 119/271 (43%), Gaps = 16/271 (5%)
Query: 62 VFQQSEKFAKVENQYQLLKLETNEFQQLQSKISLISEK---WQKSEAIMEQLKSFQIIAH 118
V ++ K + E + +LE + QQ+Q+K+ + Q++ A + + KS + A
Sbjct: 1271 VVMETNKMLREEKE----RLE-QDLQQMQAKVRKLELDILPLQEANAELSE-KSGMLQAE 1324
Query: 119 LKRLQEEINEVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTD 178
K L+E++ K + + +Q + T + + + T + + +I +K +
Sbjct: 1325 KKLLEEDVKRWKARNQHLVSQQ---KDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAE 1381
Query: 179 IRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQR 238
I R + +T+ +L S++E NK+ + EK T++ DL + ID + KT ++ +
Sbjct: 1382 IARSNASLTNNQNLIQSLKEDLNKV-RTEKETIQK--DLDAKIIDIQEKV-KTITQVKKI 1437
Query: 239 INSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLV 298
K ELK+ DK + GD + +V +LK + + LE V
Sbjct: 1438 GRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQV 1497
Query: 299 NDLTLRIGRLVTDLLQREKEIAFLSEKISNL 329
+L + T+ +++ L ++S L
Sbjct: 1498 ENLQKTLSEKETEARNLQEQTVQLQSELSRL 1528
Score = 35.8 bits (81), Expect = 0.059
Identities = 56/311 (18%), Positives = 118/311 (37%), Gaps = 57/311 (18%)
Query: 65 QSEKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKR--- 121
+ E+ +++E Q LK Q+ + ++ ++ +A ME+ ++ AH+K
Sbjct: 229 KKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNL 288
Query: 122 LQEEINEVKTWSNRITEKQDILNNSLT-------TLSQDITKVDQSTTSMAKDVGLKITS 174
+ ++ + SN +T + L+ L + + +V+QS M K++ KI
Sbjct: 289 YKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGR 348
Query: 175 VKTDIRRISGL-------------------------VTDVISLTDSVQELENK------- 202
++ ++ + L V ++ + EL N
Sbjct: 349 LEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQ 408
Query: 203 --IEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLTELKSDFDKHTDRF 260
+EK+E + D + ++ A + K E +R +K + L ++
Sbjct: 409 LLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYER---AQKAVASLSVKLEQAMKEI 465
Query: 261 LSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLLQREKEIA 320
L+ D K K + L++D R+E V DL+ +I L+ +L +
Sbjct: 466 QRLQEDTDKANKQSSV----------LERDNRRMEIQVKDLSQQIRVLLMELEEARGNHV 515
Query: 321 FLSEKISNLTI 331
E++S+ I
Sbjct: 516 IRDEEVSSADI 526
Score = 33.5 bits (75), Expect = 0.29
Identities = 42/231 (18%), Positives = 100/231 (43%), Gaps = 29/231 (12%)
Query: 73 ENQYQLLKLETNEFQQLQSKISLISEKWQK-SEAIMEQLKSFQIIAHLKRLQEEINEVKT 131
E ++++ ++E+ ++Q ++ L+ + Q+ +++ + + Q+ A EE+ +
Sbjct: 1211 ETRFEVAQVESLRYRQ---RVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTE 1267
Query: 132 WSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVTDVIS 191
N + E +L L QD+ ++ + D+ L + ++ SG++
Sbjct: 1268 TMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDI-LPLQEANAELSEKSGML----- 1321
Query: 192 LTDSVQELENKI--EKVEKNTVKNIGDLLSSSIDRTATLRKTASE---NSQRINSVKKTL 246
+ E K+ E V++ +N + T RK SE +++RI + + +
Sbjct: 1322 ------QAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEI 1375
Query: 247 TELKSDFDK-------HTDRFLSLEGDRAKV-LKTVTFANDLKPKVYNLKK 289
LK++ + + + SL+ D KV + T DL K+ ++++
Sbjct: 1376 GRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQE 1426
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 44.3 bits (103), Expect = 2e-04
Identities = 73/331 (22%), Positives = 131/331 (39%), Gaps = 81/331 (24%)
Query: 62 VFQQSEKFAKVENQYQLLKLETNEFQQLQSKI----------SLISEKWQKSEAIMEQLK 111
+ + E+F + +Q + LK E + Q L S+ I EK +K + + E L+
Sbjct: 693 ISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLE 752
Query: 112 SFQIIAHLKRLQEEINEVKTWSNRIT-EKQDILNN-----SLTTLSQDITKVDQSTTSMA 165
+ I K +EE+N ++T ++ +T E QD+ S +L +++ KV
Sbjct: 753 TGLIQVATK--EEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKI 810
Query: 166 K---------------------DVGLKITSVKTDIRRISGLVTDVISLTDSVQELENKIE 204
K D+ +I ++K +I + +S+T VQEL+N
Sbjct: 811 KSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQN--- 867
Query: 205 KVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLE 264
LL ++ T++ E + + + K L +L+ + + SL+
Sbjct: 868 ------------LLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENE-------SLK 908
Query: 265 GDRAKVLKTVTFANDLKPKVYNLKK-----DFSRLEPLVNDLTLRIGRLVTDLLQREKEI 319
+V + +NLK+ F LE ++ + + RL L +RE +
Sbjct: 909 AHVQEVAQ------------HNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESD- 955
Query: 320 AFLSEKISNLTIVQAEIKDIKDEIAHISDMN 350
LS K L VQ E K K +I + N
Sbjct: 956 --LSSKTQLLQDVQDENKLFKSQIEQLKQQN 984
Score = 38.5 bits (88), Expect = 0.009
Identities = 50/254 (19%), Positives = 110/254 (43%), Gaps = 26/254 (10%)
Query: 68 KFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEIN 127
K + + + LL+LE +++ + ++ I +K Q+S + ++ +++ ++ E
Sbjct: 1121 KLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRS--VEQEENKWKV-----KVDESHK 1173
Query: 128 EVKTWSNRITEKQDILNNSLTTLSQDITKVDQSTTSMAKDVGLKITSVKTDIRRISGLVT 187
+K + T + L L + ++DI + + + ++ K ++ R S VT
Sbjct: 1174 TIKQMQSSFTSSEQELER-LRSENKDIENLRREREHLEMELE------KAEMER-STYVT 1225
Query: 188 DVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKTASENSQRINSVKKTLT 247
+V L D + EL+ K++ V+ +L TL K +E ++R V L
Sbjct: 1226 EVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNER-QKVAGDLH 1284
Query: 248 ELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTLRIGR 307
+ + + + + GD TV +D+ P+ + +K+ + +N ++ +
Sbjct: 1285 KAQQSLELIQSKIVKAAGD-----TTVIENSDVSPETESSEKE--TMSVSLNQTVTQLQQ 1337
Query: 308 L---VTDLLQREKE 318
L V L +EKE
Sbjct: 1338 LLQAVNQQLTKEKE 1351
Score = 38.1 bits (87), Expect = 0.012
Identities = 46/205 (22%), Positives = 88/205 (42%), Gaps = 23/205 (11%)
Query: 67 EKFAKVENQYQLLKLETNEFQQLQSKISLISEKWQKSEAIMEQLKSFQIIAHLKRLQEEI 126
EK + N + L+ E + L++ + +++ K + Q + +I+ L+E+
Sbjct: 885 EKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIV-----LKEKE 939
Query: 127 NEVKTWSNRITEKQDILNNSLTTLS--QDITKVDQSTTSMAKDVG-------------LK 171
NE+K + E++ L++ L QD K+ +S K LK
Sbjct: 940 NELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLK 999
Query: 172 ITSVKTDIRRISGLVTDVISLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTATLRKT 231
+ S + + ISGL ++ SL D+V+ K + + + + L S+ + KT
Sbjct: 1000 VISERE--KEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKT 1057
Query: 232 ASENSQRINSVKKTLTE-LKSDFDK 255
+ E Q++ +V+ E LK F K
Sbjct: 1058 SKERQQQVEAVELEAKEVLKKLFPK 1082
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,972,009
Number of Sequences: 37866
Number of extensions: 452145
Number of successful extensions: 3093
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 320
Number of HSP's that attempted gapping in prelim test: 2625
Number of HSP's gapped (non-prelim): 730
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.