Search of human proteins with 41406064

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo
sapiens]
         (1976 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]  3814   0.0  
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]   3013   0.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...  2979   0.0  
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...  2972   0.0  
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...  2961   0.0  
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...  2954   0.0  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]         2612   0.0  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]         2605   0.0  
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]         2588   0.0  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...  1422   0.0  
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...  1413   0.0  
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...  1413   0.0  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...  1407   0.0  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...  1405   0.0  
gi|156104908 myosin heavy chain 6 [Homo sapiens]                     1403   0.0  
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...  1400   0.0  
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...  1396   0.0  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...  1383   0.0  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...  1375   0.0  
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]             1255   0.0  
gi|153945715 myosin VC [Homo sapiens]                                 587   e-167
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       587   e-167
gi|122937345 myosin VB [Homo sapiens]                                 585   e-166
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       582   e-166
gi|28416946 myosin 18A isoform a [Homo sapiens]                       582   e-165
gi|42794779 myosin 18A isoform b [Homo sapiens]                       581   e-165
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     503   e-142
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     503   e-142
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     503   e-142
gi|154354979 myosin X [Homo sapiens]                                  497   e-140

>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 3814 bits (9890), Expect = 0.0
 Identities = 1976/1976 (100%), Positives = 1976/1976 (100%)

Query: 1    MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV 60
            MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV
Sbjct: 1    MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV 60

Query: 61   ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL 120
            ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL
Sbjct: 61   ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL 120

Query: 121  FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES 180
            FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES
Sbjct: 121  FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSS 240
            GAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSS
Sbjct: 181  GAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSS 240

Query: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLL 300
            RFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLL
Sbjct: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLL 300

Query: 301  LEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNIS 360
            LEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNIS
Sbjct: 301  LEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNIS 360

Query: 361  FKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFA 420
            FKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFA
Sbjct: 361  FKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFA 420

Query: 421  VEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTN 480
            VEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTN
Sbjct: 421  VEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTN 480

Query: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW 540
            EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW
Sbjct: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW 540

Query: 541  FPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLN 600
            FPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLN
Sbjct: 541  FPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLN 600

Query: 601  DNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKES 660
            DNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKES
Sbjct: 601  DNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKES 660

Query: 661  LTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIV 720
            LTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIV
Sbjct: 661  LTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIV 720

Query: 721  FQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEE 780
            FQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEE
Sbjct: 721  FQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEE 780

Query: 781  ERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTK 840
            ERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTK
Sbjct: 781  ERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTK 840

Query: 841  VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET 900
            VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET
Sbjct: 841  VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET 900

Query: 901  ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960
            ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD
Sbjct: 901  ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960

Query: 961  EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
            EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE
Sbjct: 961  EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020

Query: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
            KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080

Query: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
            LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ
Sbjct: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140

Query: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200
            KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR
Sbjct: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200

Query: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260
            HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ
Sbjct: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260

Query: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
            VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT
Sbjct: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320

Query: 1321 QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
            QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV
Sbjct: 1321 QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380

Query: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440
            DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR
Sbjct: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440

Query: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500
            QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE
Sbjct: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500

Query: 1501 EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED 1560
            EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED
Sbjct: 1501 EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED 1560

Query: 1561 AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK 1620
            AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK
Sbjct: 1561 AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK 1620

Query: 1621 KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEK 1680
            KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEK
Sbjct: 1621 KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEK 1680

Query: 1681 KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ 1740
            KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ
Sbjct: 1681 KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ 1740

Query: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK 1800
            LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK
Sbjct: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK 1800

Query: 1801 LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED 1860
            LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED
Sbjct: 1801 LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED 1860

Query: 1861 ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE 1920
            ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE
Sbjct: 1861 ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE 1920

Query: 1921 VSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQSE 1976
            VSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQSE
Sbjct: 1921 VSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQSE 1976


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 3013 bits (7811), Expect = 0.0
 Identities = 1533/1965 (78%), Positives = 1743/1965 (88%), Gaps = 12/1965 (0%)

Query: 11   ERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAM 70
            ++YL+VD+  I NP  QADW AKKLVW+PS++ GFE AS+KEE G+E +VEL ENGKK  
Sbjct: 7    DKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVK 66

Query: 71   VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKN 130
            VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLK+RYYSGLIYTYSGLFCVVINPYKN
Sbjct: 67   VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKN 126

Query: 131  LPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKK 190
            LPIYSE I+EMY+GKKRHEMPPHIYAI+++AYR M+QDREDQSILCTGESGAGKTENTKK
Sbjct: 127  LPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKK 186

Query: 191  VIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINF 250
            VIQYLA+VASSHK +KD    GELERQLLQANPILE+FGNAKTVKNDNSSRFGKFIRINF
Sbjct: 187  VIQYLAYVASSHKSKKDQ---GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 243

Query: 251  DVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFL 310
            DV GYIVGANIETYLLEKSRA+RQAK+ERTFHIFY LLSGAGEHLK+DLLLE +N YRFL
Sbjct: 244  DVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFL 303

Query: 311  SNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQA 370
            SNG++ IPGQQDKD FQETMEAM IMG   EE + +L+V+S VLQ GNI FKKERNTDQA
Sbjct: 304  SNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQA 363

Query: 371  SMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYE 430
            SMP+NT AQK+ HLLG+NV +FTR ILTPRIKVGRDYVQKAQTKEQADFA+EALAKATYE
Sbjct: 364  SMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYE 423

Query: 431  RLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHT 490
            R+FRWLV RINKALD+TKRQGASFIGILDIAGFEIF+LNSFEQLCINYTNEKLQQLFNHT
Sbjct: 424  RMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHT 483

Query: 491  MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFV 550
            MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIE+PA PPG+LALLDEECWFPKATDK+FV
Sbjct: 484  MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFV 543

Query: 551  EKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQS 610
            EK++QEQG+H KFQKP+QLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDN+ATLLHQS
Sbjct: 544  EKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQS 603

Query: 611  SDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRN 670
            SD+FV+ELWKDVDRI+GLDQV GM+ETA   A+KT+KGMFRTVGQLYKE L KLMATLRN
Sbjct: 604  SDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRN 663

Query: 671  TNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 730
            TNPNFVRCIIPNHEK+AGKLDPHLVLDQLRCNGVLEGIRICRQGFPNR+VFQEFRQRYEI
Sbjct: 664  TNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEI 723

Query: 731  LTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDII 790
            LTPN+IPKGFMDGKQAC  MI+ALELD NLYRIGQSK+FFRAGVLAHLEEERDLKITD+I
Sbjct: 724  LTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVI 783

Query: 791  IFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQ 850
            I FQA CRGYLARKAFAK+QQQL+A+KVLQRNCAAYLKLR+WQWWR+FTKVKPLLQV+RQ
Sbjct: 784  IGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQ 843

Query: 851  EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
            EEE+ AK+EEL+KV+EKQ   E  L EME    QL+ EK  L EQLQAETEL AEAEE+R
Sbjct: 844  EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903

Query: 911  ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
            ARL AKKQELEEI HDLE+RVEEEEER Q LQ EKKKMQ +IQ+LEEQL+EEE ARQKLQ
Sbjct: 904  ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963

Query: 971  LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030
            LEKVT EAK+KK+EEE ++LEDQN K  KEKKL+EDRIAE ++ L EEEEK+K+LAK++N
Sbjct: 964  LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKN 1023

Query: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
            K E MI+DLEERL++EEK RQELEK +RKL+G++TDL DQIAELQAQI ELK+QLAKKEE
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083

Query: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEA 1150
            ELQ ALAR ++E   KN ALK +REL++QI+ELQED ESE+ASRNKAEKQKRDL EELEA
Sbjct: 1084 ELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEA 1143

Query: 1151 LKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSE 1210
            LKTELEDTLD+TAAQQELR+KREQEV  LKK LEEE K HEAQIQ+MRQ+H+ A+EEL+E
Sbjct: 1144 LKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAE 1203

Query: 1211 QLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSE 1270
            QLEQ KR KANLEK KQ LE +  ELA EVKVL Q K +SEHKRKK++AQ+QEL  K +E
Sbjct: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263

Query: 1271 GDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQ 1330
            G+R+R ELA+K +KLQ ELDNV+ LL +++ K  K  KD ++LESQLQDTQELLQEE RQ
Sbjct: 1264 GERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ 1323

Query: 1331 KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESL 1390
            KL+LS++++Q+E+EKNS +EQ EEEEEA+ NLEKQ+  L +Q+AD KKK++D +G +E+ 
Sbjct: 1324 KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETA 1383

Query: 1391 EEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ 1450
            EE K+KL KD E LSQR EEK  AYDKLEKTK RLQQELDDL VDLDHQRQ A NLEKKQ
Sbjct: 1384 EEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ 1443

Query: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLR 1510
            KKFDQLLAEEK+ISA+YAEERDRAEAEAREKETKALSLARALEEA+E K E ER NKQ R
Sbjct: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFR 1503

Query: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQ 1570
             +MEDLMSSKDDVGK+VHELEKSKRALEQQVEEM+TQLEELEDELQATEDAKLRLEVN+Q
Sbjct: 1504 TEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQ 1563

Query: 1571 AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE 1630
            AMKAQFERDLQ RDEQ+EEKK+ L++QVRE+EAELEDERKQR++AVA++KK+E+DLKDLE
Sbjct: 1564 AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623

Query: 1631 AQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEIL 1690
            A I++ANK RDE IKQLRKLQAQMKD  REL++ RASR+EI AQ+KE+EKKLKS+EAE++
Sbjct: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683

Query: 1691 QLQEELASSERARRHAEQERDELADEITNSASGKSAL-LDEKRRLEARIAQLEEELEEEQ 1749
            QLQEELA++ERA+R A+QERDELADEI NS SGK AL L+EKRRLEARIAQLEEELEEEQ
Sbjct: 1684 QLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALEEKRRLEARIAQLEEELEEEQ 1742

Query: 1750 SNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVK 1809
             N EL+NDR +K  LQ+D +N +L  ERS AQK++NARQQLERQNKELK KLQE+EG VK
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802

Query: 1810 SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYK 1869
            SK+KA+I+ALEAKI QLEEQL+ E KER AA K VRRTEKKLK++ +QV+DERR+A+QYK
Sbjct: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862

Query: 1870 EQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
            +Q +KA+ R+KQLKRQLEEAEEEA RANASRRKLQREL+DATE  + ++REVS+LKN+LR
Sbjct: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922

Query: 1930 RGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQ 1974
            RG        R  R+     GA  + SD++ + K +D  E +P +
Sbjct: 1923 RGDLPFVVPRRMARK-----GAG-DGSDEEVDGK-ADGAEAKPAE 1960


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 2979 bits (7724), Expect = 0.0
 Identities = 1504/1972 (76%), Positives = 1751/1972 (88%), Gaps = 4/1972 (0%)

Query: 1    MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV 60
            MAQ+  L D E++LFVD+  I +P  QADW AK+LVW+PSE+ GFEAASIKEE+GDEV+V
Sbjct: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60

Query: 61   ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL 120
            EL ENGKK  V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL++RY+SGLIYTYSGL
Sbjct: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120

Query: 121  FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES 180
            FCVV+NPYK+LPIYSE I++MY+GKKRHEMPPHIYAI+++AYR MLQDREDQSILCTGES
Sbjct: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSS 240
            GAGKTENTKKVIQYLA VASSHKG+KD +I GELE+QLLQANPILE+FGNAKTVKNDNSS
Sbjct: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240

Query: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLL 300
            RFGKFIRINFDVTGYIVGANIETYLLEKSRA+RQA+DERTFHIFY +++GA E ++SDLL
Sbjct: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300

Query: 301  LEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNIS 360
            LEGFNNY FLSNG++PIP  QD + FQET+EAM IMGFS EE LS+LKVVSSVLQ GNI 
Sbjct: 301  LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360

Query: 361  FKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFA 420
            FKKERNTDQASMP+NT AQK+CHL+G+NV +FTR+ILTPRIKVGRD VQKAQTKEQADFA
Sbjct: 361  FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420

Query: 421  VEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTN 480
            VEALAKATYERLFRW++ R+NKALD+T RQGASF+GILDIAGFEIFE+NSFEQLCINYTN
Sbjct: 421  VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480

Query: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW 540
            EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI+LIERP NPPGVLALLDEECW
Sbjct: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540

Query: 541  FPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLN 600
            FPKATDK+FVEKL  EQGSH KFQKP+QLKDK +F IIHYAGKVDY A  WL KNMDPLN
Sbjct: 541  FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600

Query: 601  DNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKES 660
            DNV +LL+ SSD+FVA+LWKDVDRIVGLDQ+  MTE++  SA KTKKGMFRTVGQLYKE 
Sbjct: 601  DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660

Query: 661  LTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIV 720
            L KLM TLRNT PNFVRCIIPNHEKR+GKLD  LVL+QLRCNGVLEGIRICRQGFPNRIV
Sbjct: 661  LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720

Query: 721  FQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEE 780
            FQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYRIGQSKIFFR GVLAHLEE
Sbjct: 721  FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780

Query: 781  ERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTK 840
            ERDLKITD+I+ FQA+CRGYLARKAFAK+QQQL+A+KV+QRNCAAYLKLR+WQWWR+FTK
Sbjct: 781  ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840

Query: 841  VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET 900
            VKPLLQVTRQEEE+QAK++EL K KE+Q K E EL+E+E+KH QL EEKN+L EQLQAET
Sbjct: 841  VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900

Query: 901  ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960
            EL+AEAEEMR RLAAKKQELEEILH++E+R+EEEE+R Q LQ E+KKM   + DLEEQL+
Sbjct: 901  ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960

Query: 961  EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
            EEE ARQKLQLEKVTAEAKIKK+E+EIL+++DQN+K  KE+KL+E+RI++ ++ LAEEEE
Sbjct: 961  EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020

Query: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
            KAKNL K++NK E MIS+LE RLKKEEK+RQELEK KRKL+G+ +D  +QIA+LQAQI E
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080

Query: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
            LK+QLAKKEEELQ ALAR DDE   KNNALK +REL+  I++LQED +SE+A+RNKAEKQ
Sbjct: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140

Query: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200
            KRDL EELEALKTELEDTLD+TA QQELR KREQEV  LKKAL+EET++HEAQ+Q+MRQ+
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200

Query: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260
            HA A+EEL+EQLEQ KR KANL+KNKQ LE +N +LA E++VL Q K E EHK+KKL+AQ
Sbjct: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260

Query: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
            VQEL +K S+G+R R EL +K  KLQNE+++V+ +L EAE K IK AKD ASL SQLQDT
Sbjct: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320

Query: 1321 QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
            QELLQEETRQKLN+S+++RQLEEE+NSLQ+Q +EE EA++NLE+ +  L  QL+D+KKK+
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380

Query: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440
             D   T+E+LEE KK+  K+ E L+Q+ EEKA AYDKLEKTKNRLQQELDDL VDLD+QR
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440

Query: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500
            Q+ SNLEKKQ+KFDQLLAEEK+IS++YA+ERDRAEAEAREKETKALSLARALEEALEAKE
Sbjct: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500

Query: 1501 EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED 1560
            E ER NK L+A+MEDL+SSKDDVGKNVHELEKSKRALE Q+EEM+TQLEELEDELQATED
Sbjct: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560

Query: 1561 AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK 1620
            AKLRLEVNMQA+K QFERDLQ RDEQNEEK+R L +Q+ E E ELEDERKQRALA A+KK
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620

Query: 1621 KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEK 1680
            K+E DLKDLE Q ++A K R+E IKQLRKLQAQMKD+QRELE+ARASRDEIFA +KE+EK
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680

Query: 1681 KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ 1740
            K KSLEA+++QLQE+LA++ERAR+ A+ E++ELA+E+ +S SG++AL DEKRRLEARIAQ
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740

Query: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK 1800
            LEEELEEEQ NME ++DR RK T Q + L+ ELA ERS AQK+++ARQQLERQNKEL++K
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800

Query: 1801 LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED 1860
            L E+EGAVKSKFK+TI+ALEAKI QLEEQ+EQEA+E+ AA K +++ +KKLKEI +QVED
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860

Query: 1861 ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE 1920
            ER+ A+QYKEQ EK NAR+KQLKRQLEEAEEE+ R NA+RRKLQRELD+ATE+NE + RE
Sbjct: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920

Query: 1921 VSTLKNRLRRGGPISF-SSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQ 1971
            V+ LK++LRRG   SF  S RSG R++ +E A  + S+++T+++ +D N T+
Sbjct: 1921 VNALKSKLRRGNETSFVPSRRSGGRRV-IENA--DGSEEETDTRDADFNGTK 1969


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 2972 bits (7706), Expect = 0.0
 Identities = 1504/1979 (75%), Positives = 1751/1979 (88%), Gaps = 11/1979 (0%)

Query: 1    MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV 60
            MAQ+  L D E++LFVD+  I +P  QADW AK+LVW+PSE+ GFEAASIKEE+GDEV+V
Sbjct: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60

Query: 61   ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL 120
            EL ENGKK  V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL++RY+SGLIYTYSGL
Sbjct: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120

Query: 121  FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES 180
            FCVV+NPYK+LPIYSE I++MY+GKKRHEMPPHIYAI+++AYR MLQDREDQSILCTGES
Sbjct: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAHVASSHKGRKDHNIP-------GELERQLLQANPILESFGNAKT 233
            GAGKTENTKKVIQYLA VASSHKG+KD +I        GELE+QLLQANPILE+FGNAKT
Sbjct: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKT 240

Query: 234  VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGE 293
            VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRA+RQA+DERTFHIFY +++GA E
Sbjct: 241  VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 300

Query: 294  HLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSV 353
             ++SDLLLEGFNNY FLSNG++PIP  QD + FQET+EAM IMGFS EE LS+LKVVSSV
Sbjct: 301  KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 360

Query: 354  LQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQT 413
            LQ GNI FKKERNTDQASMP+NT AQK+CHL+G+NV +FTR+ILTPRIKVGRD VQKAQT
Sbjct: 361  LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 420

Query: 414  KEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQ 473
            KEQADFAVEALAKATYERLFRW++ R+NKALD+T RQGASF+GILDIAGFEIFE+NSFEQ
Sbjct: 421  KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 480

Query: 474  LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLA 533
            LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI+LIERP NPPGVLA
Sbjct: 481  LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 540

Query: 534  LLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLM 593
            LLDEECWFPKATDK+FVEKL  EQGSH KFQKP+QLKDK +F IIHYAGKVDY A  WL 
Sbjct: 541  LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 600

Query: 594  KNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTV 653
            KNMDPLNDNV +LL+ SSD+FVA+LWKDVDRIVGLDQ+  MTE++  SA KTKKGMFRTV
Sbjct: 601  KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 660

Query: 654  GQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQ 713
            GQLYKE L KLM TLRNT PNFVRCIIPNHEKR+GKLD  LVL+QLRCNGVLEGIRICRQ
Sbjct: 661  GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 720

Query: 714  GFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAG 773
            GFPNRIVFQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYRIGQSKIFFR G
Sbjct: 721  GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 780

Query: 774  VLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQ 833
            VLAHLEEERDLKITD+I+ FQA+CRGYLARKAFAK+QQQL+A+KV+QRNCAAYLKLR+WQ
Sbjct: 781  VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 840

Query: 834  WWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILA 893
            WWR+FTKVKPLLQVTRQEEE+QAK++EL K KE+Q K E EL+E+E+KH QL EEKN+L 
Sbjct: 841  WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900

Query: 894  EQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953
            EQLQAETEL+AEAEEMR RLAAKKQELEEILH++E+R+EEEE+R Q LQ E+KKM   + 
Sbjct: 901  EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960

Query: 954  DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013
            DLEEQL+EEE ARQKLQLEKVTAEAKIKK+E+EIL+++DQN+K  KE+KL+E+RI++ ++
Sbjct: 961  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020

Query: 1014 QLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAE 1073
             LAEEEEKAKNL K++NK E MIS+LE RLKKEEK+RQELEK KRKL+G+ +D  +QIA+
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080

Query: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133
            LQAQI ELK+QLAKKEEELQ ALAR DDE   KNNALK +REL+  I++LQED +SE+A+
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140

Query: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 1193
            RNKAEKQKRDL EELEALKTELEDTLD+TA QQELR KREQEV  LKKAL+EET++HEAQ
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200

Query: 1194 IQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1253
            +Q+MRQ+HA A+EEL+EQLEQ KR KANL+KNKQ LE +N +LA E++VL Q K E EHK
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1260

Query: 1254 RKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL 1313
            +KKL+AQVQEL +K S+G+R R EL +K  KLQNE+++V+ +L EAE K IK AKD ASL
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320

Query: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
             SQLQDTQELLQEETRQKLN+S+++RQLEEE+NSLQ+Q +EE EA++NLE+ +  L  QL
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380

Query: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLT 1433
            +D+KKK+ D   T+E+LEE KK+  K+ E L+Q+ EEKA AYDKLEKTKNRLQQELDDL 
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440

Query: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493
            VDLD+QRQ+ SNLEKKQ+KFDQLLAEEK+IS++YA+ERDRAEAEAREKETKALSLARALE
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500

Query: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 1553
            EALEAKEE ER NK L+A+MEDL+SSKDDVGKNVHELEKSKRALE Q+EEM+TQLEELED
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560

Query: 1554 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRA 1613
            ELQATEDAKLRLEVNMQA+K QFERDLQ RDEQNEEK+R L +Q+ E E ELEDERKQRA
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620

Query: 1614 LAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFA 1673
            LA A+KKK+E DLKDLE Q ++A K R+E IKQLRKLQAQMKD+QRELE+ARASRDEIFA
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1680

Query: 1674 QSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRR 1733
             +KE+EKK KSLEA+++QLQE+LA++ERAR+ A+ E++ELA+E+ +S SG++AL DEKRR
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1740

Query: 1734 LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQ 1793
            LEARIAQLEEELEEEQ NME ++DR RK T Q + L+ ELA ERS AQK+++ARQQLERQ
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800

Query: 1794 NKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKE 1853
            NKEL++KL E+EGAVKSKFK+TI+ALEAKI QLEEQ+EQEA+E+ AA K +++ +KKLKE
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860

Query: 1854 IFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEA 1913
            I +QVEDER+ A+QYKEQ EK NAR+KQLKRQLEEAEEE+ R NA+RRKLQRELD+ATE+
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920

Query: 1914 NEGLSREVSTLKNRLRRGGPISF-SSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQ 1971
            NE + REV+ LK++LRRG   SF  S RSG R++ +E A  + S+++T+++ +D N T+
Sbjct: 1921 NEAMGREVNALKSKLRRGNETSFVPSRRSGGRRV-IENA--DGSEEETDTRDADFNGTK 1976


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 2961 bits (7677), Expect = 0.0
 Identities = 1489/1933 (77%), Positives = 1724/1933 (89%)

Query: 1    MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV 60
            MAQ+  L D E++LFVD+  I +P  QADW AK+LVW+PSE+ GFEAASIKEE+GDEV+V
Sbjct: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60

Query: 61   ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL 120
            EL ENGKK  V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL++RY+SGLIYTYSGL
Sbjct: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120

Query: 121  FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES 180
            FCVV+NPYK+LPIYSE I++MY+GKKRHEMPPHIYAI+++AYR MLQDREDQSILCTGES
Sbjct: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSS 240
            GAGKTENTKKVIQYLA VASSHKG+KD +I GELE+QLLQANPILE+FGNAKTVKNDNSS
Sbjct: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240

Query: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLL 300
            RFGKFIRINFDVTGYIVGANIETYLLEKSRA+RQA+DERTFHIFY +++GA E ++SDLL
Sbjct: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300

Query: 301  LEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNIS 360
            LEGFNNY FLSNG++PIP  QD + FQET+EAM IMGFS EE LS+LKVVSSVLQ GNI 
Sbjct: 301  LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360

Query: 361  FKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFA 420
            FKKERNTDQASMP+NT AQK+CHL+G+NV +FTR+ILTPRIKVGRD VQKAQTKEQADFA
Sbjct: 361  FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420

Query: 421  VEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTN 480
            VEALAKATYERLFRW++ R+NKALD+T RQGASF+GILDIAGFEIFE+NSFEQLCINYTN
Sbjct: 421  VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480

Query: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW 540
            EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI+LIERP NPPGVLALLDEECW
Sbjct: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540

Query: 541  FPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLN 600
            FPKATDK+FVEKL  EQGSH KFQKP+QLKDK +F IIHYAGKVDY A  WL KNMDPLN
Sbjct: 541  FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600

Query: 601  DNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKES 660
            DNV +LL+ SSD+FVA+LWKDVDRIVGLDQ+  MTE++  SA KTKKGMFRTVGQLYKE 
Sbjct: 601  DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660

Query: 661  LTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIV 720
            L KLM TLRNT PNFVRCIIPNHEKR+GKLD  LVL+QLRCNGVLEGIRICRQGFPNRIV
Sbjct: 661  LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720

Query: 721  FQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEE 780
            FQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYRIGQSKIFFR GVLAHLEE
Sbjct: 721  FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780

Query: 781  ERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTK 840
            ERDLKITD+I+ FQA+CRGYLARKAFAK+QQQL+A+KV+QRNCAAYLKLR+WQWWR+FTK
Sbjct: 781  ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840

Query: 841  VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET 900
            VKPLLQVTRQEEE+QAK++EL K KE+Q K E EL+E+E+KH QL EEKN+L EQLQAET
Sbjct: 841  VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900

Query: 901  ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960
            EL+AEAEEMR RLAAKKQELEEILH++E+R+EEEE+R Q LQ E+KKM   + DLEEQL+
Sbjct: 901  ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960

Query: 961  EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
            EEE ARQKLQLEKVTAEAKIKK+E+EIL+++DQN+K  KE+KL+E+RI++ ++ LAEEEE
Sbjct: 961  EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020

Query: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
            KAKNL K++NK E MIS+LE RLKKEEK+RQELEK KRKL+G+ +D  +QIA+LQAQI E
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080

Query: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
            LK+QLAKKEEELQ ALAR DDE   KNNALK +REL+  I++LQED +SE+A+RNKAEKQ
Sbjct: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140

Query: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200
            KRDL EELEALKTELEDTLD+TA QQELR KREQEV  LKKAL+EET++HEAQ+Q+MRQ+
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200

Query: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260
            HA A+EEL+EQLEQ KR KANL+KNKQ LE +N +LA E++VL Q K E EHK+KKL+AQ
Sbjct: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260

Query: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
            VQEL +K S+G+R R EL +K  KLQNE+++V+ +L EAE K IK AKD ASL SQLQDT
Sbjct: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320

Query: 1321 QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
            QELLQEETRQKLN+S+++RQLEEE+NSLQ+Q +EE EA++NLE+ +  L  QL+D+KKK+
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380

Query: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440
             D   T+E+LEE KK+  K+ E L+Q+ EEKA AYDKLEKTKNRLQQELDDL VDLD+QR
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440

Query: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500
            Q+ SNLEKKQ+KFDQLLAEEK+IS++YA+ERDRAEAEAREKETKALSLARALEEALEAKE
Sbjct: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500

Query: 1501 EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED 1560
            E ER NK L+A+MEDL+SSKDDVGKNVHELEKSKRALE Q+EEM+TQLEELEDELQATED
Sbjct: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560

Query: 1561 AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK 1620
            AKLRLEVNMQA+K QFERDLQ RDEQNEEK+R L +Q+ E E ELEDERKQRALA A+KK
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620

Query: 1621 KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEK 1680
            K+E DLKDLE Q ++A K R+E IKQLRKLQAQMKD+QRELE+ARASRDEIFA +KE+EK
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680

Query: 1681 KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ 1740
            K KSLEA+++QLQE+LA++ERAR+ A+ E++ELA+E+ +S SG++AL DEKRRLEARIAQ
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740

Query: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK 1800
            LEEELEEEQ NME ++DR RK T Q + L+ ELA ERS AQK+++ARQQLERQNKEL++K
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800

Query: 1801 LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED 1860
            L E+EGAVKSKFK+TI+ALEAKI QLEEQ+EQEA+E+ AA K +++ +KKLKEI +QVED
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860

Query: 1861 ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE 1920
            ER+ A+QYKEQ EK NAR+KQLKRQLEEAEEE+ R NA+RRKLQRELD+ATE+NE + RE
Sbjct: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920

Query: 1921 VSTLKNRLRRGGP 1933
            V+ LK++LR   P
Sbjct: 1921 VNALKSKLRGPPP 1933


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 2954 bits (7659), Expect = 0.0
 Identities = 1489/1940 (76%), Positives = 1724/1940 (88%), Gaps = 7/1940 (0%)

Query: 1    MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV 60
            MAQ+  L D E++LFVD+  I +P  QADW AK+LVW+PSE+ GFEAASIKEE+GDEV+V
Sbjct: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60

Query: 61   ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL 120
            EL ENGKK  V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL++RY+SGLIYTYSGL
Sbjct: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120

Query: 121  FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES 180
            FCVV+NPYK+LPIYSE I++MY+GKKRHEMPPHIYAI+++AYR MLQDREDQSILCTGES
Sbjct: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAHVASSHKGRKDHNIP-------GELERQLLQANPILESFGNAKT 233
            GAGKTENTKKVIQYLA VASSHKG+KD +I        GELE+QLLQANPILE+FGNAKT
Sbjct: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKT 240

Query: 234  VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGE 293
            VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRA+RQA+DERTFHIFY +++GA E
Sbjct: 241  VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 300

Query: 294  HLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSV 353
             ++SDLLLEGFNNY FLSNG++PIP  QD + FQET+EAM IMGFS EE LS+LKVVSSV
Sbjct: 301  KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 360

Query: 354  LQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQT 413
            LQ GNI FKKERNTDQASMP+NT AQK+CHL+G+NV +FTR+ILTPRIKVGRD VQKAQT
Sbjct: 361  LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 420

Query: 414  KEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQ 473
            KEQADFAVEALAKATYERLFRW++ R+NKALD+T RQGASF+GILDIAGFEIFE+NSFEQ
Sbjct: 421  KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 480

Query: 474  LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLA 533
            LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI+LIERP NPPGVLA
Sbjct: 481  LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 540

Query: 534  LLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLM 593
            LLDEECWFPKATDK+FVEKL  EQGSH KFQKP+QLKDK +F IIHYAGKVDY A  WL 
Sbjct: 541  LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 600

Query: 594  KNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTV 653
            KNMDPLNDNV +LL+ SSD+FVA+LWKDVDRIVGLDQ+  MTE++  SA KTKKGMFRTV
Sbjct: 601  KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 660

Query: 654  GQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQ 713
            GQLYKE L KLM TLRNT PNFVRCIIPNHEKR+GKLD  LVL+QLRCNGVLEGIRICRQ
Sbjct: 661  GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 720

Query: 714  GFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAG 773
            GFPNRIVFQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYRIGQSKIFFR G
Sbjct: 721  GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 780

Query: 774  VLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQ 833
            VLAHLEEERDLKITD+I+ FQA+CRGYLARKAFAK+QQQL+A+KV+QRNCAAYLKLR+WQ
Sbjct: 781  VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 840

Query: 834  WWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILA 893
            WWR+FTKVKPLLQVTRQEEE+QAK++EL K KE+Q K E EL+E+E+KH QL EEKN+L 
Sbjct: 841  WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900

Query: 894  EQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953
            EQLQAETEL+AEAEEMR RLAAKKQELEEILH++E+R+EEEE+R Q LQ E+KKM   + 
Sbjct: 901  EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960

Query: 954  DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013
            DLEEQL+EEE ARQKLQLEKVTAEAKIKK+E+EIL+++DQN+K  KE+KL+E+RI++ ++
Sbjct: 961  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020

Query: 1014 QLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAE 1073
             LAEEEEKAKNL K++NK E MIS+LE RLKKEEK+RQELEK KRKL+G+ +D  +QIA+
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080

Query: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133
            LQAQI ELK+QLAKKEEELQ ALAR DDE   KNNALK +REL+  I++LQED +SE+A+
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140

Query: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 1193
            RNKAEKQKRDL EELEALKTELEDTLD+TA QQELR KREQEV  LKKAL+EET++HEAQ
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200

Query: 1194 IQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK 1253
            +Q+MRQ+HA A+EEL+EQLEQ KR KANL+KNKQ LE +N +LA E++VL Q K E EHK
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1260

Query: 1254 RKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL 1313
            +KKL+AQVQEL +K S+G+R R EL +K  KLQNE+++V+ +L EAE K IK AKD ASL
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320

Query: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
             SQLQDTQELLQEETRQKLN+S+++RQLEEE+NSLQ+Q +EE EA++NLE+ +  L  QL
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380

Query: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLT 1433
            +D+KKK+ D   T+E+LEE KK+  K+ E L+Q+ EEKA AYDKLEKTKNRLQQELDDL 
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440

Query: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493
            VDLD+QRQ+ SNLEKKQ+KFDQLLAEEK+IS++YA+ERDRAEAEAREKETKALSLARALE
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500

Query: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 1553
            EALEAKEE ER NK L+A+MEDL+SSKDDVGKNVHELEKSKRALE Q+EEM+TQLEELED
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560

Query: 1554 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRA 1613
            ELQATEDAKLRLEVNMQA+K QFERDLQ RDEQNEEK+R L +Q+ E E ELEDERKQRA
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620

Query: 1614 LAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFA 1673
            LA A+KKK+E DLKDLE Q ++A K R+E IKQLRKLQAQMKD+QRELE+ARASRDEIFA
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1680

Query: 1674 QSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRR 1733
             +KE+EKK KSLEA+++QLQE+LA++ERAR+ A+ E++ELA+E+ +S SG++AL DEKRR
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1740

Query: 1734 LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQ 1793
            LEARIAQLEEELEEEQ NME ++DR RK T Q + L+ ELA ERS AQK+++ARQQLERQ
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800

Query: 1794 NKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKE 1853
            NKEL++KL E+EGAVKSKFK+TI+ALEAKI QLEEQ+EQEA+E+ AA K +++ +KKLKE
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860

Query: 1854 IFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEA 1913
            I +QVEDER+ A+QYKEQ EK NAR+KQLKRQLEEAEEE+ R NA+RRKLQRELD+ATE+
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920

Query: 1914 NEGLSREVSTLKNRLRRGGP 1933
            NE + REV+ LK++LR   P
Sbjct: 1921 NEAMGREVNALKSKLRGPPP 1940


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 2612 bits (6770), Expect = 0.0
 Identities = 1314/1950 (67%), Positives = 1622/1950 (83%), Gaps = 8/1950 (0%)

Query: 27   QADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSK 86
            Q +WTA++LVW+PSE HGFEAA++++E  +E  VELAE+G++  + +D IQ+MNPPKFSK
Sbjct: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106

Query: 87   VEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK 146
             EDMAELTCLNEASVLHNL++RYYSGLIYTYSGLFCVVINPYK LPIY+E I+EMYRGKK
Sbjct: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166

Query: 147  RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRK 206
            RHE+PPH+YA++E AYR MLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS KGRK
Sbjct: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226

Query: 207  DHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
            +  +PGELERQLLQANPILE+FGNAKTVKNDNSSRFGKFIRINFDV GYIVGANIETYLL
Sbjct: 227  EPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLL 286

Query: 267  EKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNF 326
            EKSRA+RQAKDE +FHIFYQLL GAGE LK+DLLLE  ++YRFL+NG    PGQ+ ++ F
Sbjct: 287  EKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELF 345

Query: 327  QETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLG 386
            QET+E++ ++GFSHEEI+SML++VS+VLQFGNI+ K+ERNTDQA+MP+NT AQKLC LLG
Sbjct: 346  QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405

Query: 387  MNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDR 446
            + V +F+RA+LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYERLFRWLV R+N+ALDR
Sbjct: 406  LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDR 465

Query: 447  TKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
            + RQGASF+GILDIAGFEIF+LNSFEQLCINYTNEKLQQLFNHTMF+LEQEEYQREGI W
Sbjct: 466  SPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPW 525

Query: 507  NFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKP 566
             F+DFGLDLQPCIDLIERPANPPG+LALLDEECWFPKATDK+FVEK+ QEQG H KFQ+P
Sbjct: 526  TFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP 585

Query: 567  RQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIV 626
            R L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDNVA LLHQS+DR  AE+WKDV+ IV
Sbjct: 586  RHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645

Query: 627  GLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKR 686
            GL+QV+ + +   G   + ++GMFRTVGQLYKESL++LMATL NTNP+FVRCI+PNHEKR
Sbjct: 646  GLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703

Query: 687  AGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQA 746
            AGKL+P LVLDQLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEILTPNAIPKGFMDGKQA
Sbjct: 704  AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763

Query: 747  CERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAF 806
            CE+MI+ALELDPNLYR+GQSKIFFRAGVLA LEEERDLK+TDII+ FQA  RGYLAR+AF
Sbjct: 764  CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823

Query: 807  AKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKE 866
             K+QQQ SAL+V+QRNCAAYLKLRHWQWWR+FTKVKPLLQVTRQ+E LQA+ +EL KV+E
Sbjct: 824  QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883

Query: 867  KQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHD 926
             Q +   E+ E++ +  QL EE+  LAEQL+AE EL AEAEE R RLAA+KQELE ++ +
Sbjct: 884  LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943

Query: 927  LESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEE 986
            LE+RV EEEE ++ +Q EKK++Q HIQ+LE  L+ EEGARQKLQLEKVT EAK+KK EE+
Sbjct: 944  LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003

Query: 987  ILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKE 1046
            +LLLEDQNSK  KE+KL+EDR+AE SSQ AEEEEK K+L K+R K E  I+D+E+RL+KE
Sbjct: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063

Query: 1047 EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHK 1106
            EK RQELEK KR+LDGE+++LQ+Q+ E Q + +EL+ QL +KEEELQ ALAR +DE   +
Sbjct: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123

Query: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166
               LK +RE QA +AE QED ESE+ +R KAEKQ+RDL EELEAL+ ELEDTLD+T AQQ
Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183

Query: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
            ELR+KREQEV ELKK LEEET+ HEA +Q++RQRH  AL EL+EQLEQA+R K   EK +
Sbjct: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243

Query: 1227 QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQ 1286
              LE +  EL  E+  LQ  + E E +R++L+ Q+QE+  +  +G+R R E AEK  + Q
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303

Query: 1287 NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN 1346
             EL+NVS  L EAE K I+ +K+ +S E+QL D QELLQEETR KL L SR+R +E E  
Sbjct: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363

Query: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQ 1406
             L+EQ EEE  AR+   +++   Q+QL++ +++ +++ G +E+ EEA+++  ++AEAL+Q
Sbjct: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423

Query: 1407 RLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISAR 1466
            RL EK    D+LE+ + RLQQELDD T+DL+ QRQ+ S LEKKQ+KFDQLLAEEK+   R
Sbjct: 1424 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483

Query: 1467 YAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKN 1526
              EER+RAEAE RE+E +ALSL RALEE  EA+EE ERQN+ LRA++E L+SSKDDVGK+
Sbjct: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543

Query: 1527 VHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQ 1586
            VHELE++ R  EQ   ++R Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQ RDE 
Sbjct: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603

Query: 1587 NEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ 1646
             EE++R L KQ+R+ E E ++ERKQR LAVA++KK+E +L++L+AQ+ +A + ++E +KQ
Sbjct: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663

Query: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHA 1706
            LRK+QAQMK+  RE+EE R SR+EIF+Q++ESEK+LK LEAE+L+LQEELA+S+RARR A
Sbjct: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723

Query: 1707 EQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQV 1766
            +Q+RDE+ADE+ N    K+A+L+EKR+LE R+ QLEEELEEEQSN ELLNDR+RK  LQV
Sbjct: 1724 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1783

Query: 1767 DTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1826
            ++L  EL+AERS + K+++ RQQLERQ +EL+ +L E +   +++ K TI+ALE+K+ Q 
Sbjct: 1784 ESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQA 1843

Query: 1827 EEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL 1886
            EEQLEQE +ER  + KLVRR EK+LKE+ +QVE+ERR ADQ ++Q+EK N R+KQLKRQL
Sbjct: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903

Query: 1887 EEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQL 1946
            EEAEEEA+RA A RR+LQREL+D TE+ E ++REV+TL+NRLRR GP++F ++R+ R+  
Sbjct: 1904 EEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR-GPLTF-TTRTVRQVF 1961

Query: 1947 HLE---GASLELSDDDTESKTSDVNETQPP 1973
             LE    +  E  +    S  S   E  PP
Sbjct: 1962 RLEEGVASDEEAEEAQPGSGPSPEPEGSPP 1991


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 2605 bits (6751), Expect = 0.0
 Identities = 1314/1958 (67%), Positives = 1622/1958 (82%), Gaps = 16/1958 (0%)

Query: 27   QADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSK 86
            Q +WTA++LVW+PSE HGFEAA++++E  +E  VELAE+G++  + +D IQ+MNPPKFSK
Sbjct: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106

Query: 87   VEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK 146
             EDMAELTCLNEASVLHNL++RYYSGLIYTYSGLFCVVINPYK LPIY+E I+EMYRGKK
Sbjct: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166

Query: 147  RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRK 206
            RHE+PPH+YA++E AYR MLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS KGRK
Sbjct: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226

Query: 207  DHNIP--------GELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
            +  +P        GELERQLLQANPILE+FGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286

Query: 259  ANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIP 318
            ANIETYLLEKSRA+RQAKDE +FHIFYQLL GAGE LK+DLLLE  ++YRFL+NG    P
Sbjct: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346

Query: 319  GQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVA 378
            GQ+ ++ FQET+E++ ++GFSHEEI+SML++VS+VLQFGNI+ K+ERNTDQA+MP+NT A
Sbjct: 347  GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405

Query: 379  QKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVH 438
            QKLC LLG+ V +F+RA+LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYERLFRWLV 
Sbjct: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465

Query: 439  RINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
            R+N+ALDR+ RQGASF+GILDIAGFEIF+LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525

Query: 499  YQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQG 558
            YQREGI W F+DFGLDLQPCIDLIERPANPPG+LALLDEECWFPKATDK+FVEK+ QEQG
Sbjct: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585

Query: 559  SHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAEL 618
             H KFQ+PR L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDNVA LLHQS+DR  AE+
Sbjct: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645

Query: 619  WKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRC 678
            WKDV+ IVGL+QV+ + +   G   + ++GMFRTVGQLYKESL++LMATL NTNP+FVRC
Sbjct: 646  WKDVEGIVGLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703

Query: 679  IIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPK 738
            I+PNHEKRAGKL+P LVLDQLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEILTPNAIPK
Sbjct: 704  IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763

Query: 739  GFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCR 798
            GFMDGKQACE+MI+ALELDPNLYR+GQSKIFFRAGVLA LEEERDLK+TDII+ FQA  R
Sbjct: 764  GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823

Query: 799  GYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKD 858
            GYLAR+AF K+QQQ SAL+V+QRNCAAYLKLRHWQWWR+FTKVKPLLQVTRQ+E LQA+ 
Sbjct: 824  GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883

Query: 859  EELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQ 918
            +EL KV+E Q +   E+ E++ +  QL EE+  LAEQL+AE EL AEAEE R RLAA+KQ
Sbjct: 884  QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943

Query: 919  ELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEA 978
            ELE ++ +LE+RV EEEE ++ +Q EKK++Q HIQ+LE  L+ EEGARQKLQLEKVT EA
Sbjct: 944  ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003

Query: 979  KIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD 1038
            K+KK EE++LLLEDQNSK  KE+KL+EDR+AE SSQ AEEEEK K+L K+R K E  I+D
Sbjct: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063

Query: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
            +E+RL+KEEK RQELEK KR+LDGE+++LQ+Q+ E Q + +EL+ QL +KEEELQ ALAR
Sbjct: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123

Query: 1099 GDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDT 1158
             +DE   +   LK +RE QA +AE QED ESE+ +R KAEKQ+RDL EELEAL+ ELEDT
Sbjct: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183

Query: 1159 LDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1218
            LD+T AQQELR+KREQEV ELKK LEEET+ HEA +Q++RQRH  AL EL+EQLEQA+R 
Sbjct: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243

Query: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVEL 1278
            K   EK +  LE +  EL  E+  LQ  + E E +R++L+ Q+QE+  +  +G+R R E 
Sbjct: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303

Query: 1279 AEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRI 1338
            AEK  + Q EL+NVS  L EAE K I+ +K+ +S E+QL D QELLQEETR KL L SR+
Sbjct: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363

Query: 1339 RQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLL 1398
            R +E E   L+EQ EEE  AR+   +++   Q+QL++ +++ +++ G +E+ EEA+++  
Sbjct: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423

Query: 1399 KDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLA 1458
            ++AEAL+QRL EK    D+LE+ + RLQQELDD T+DL+ QRQ+ S LEKKQ+KFDQLLA
Sbjct: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483

Query: 1459 EEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMS 1518
            EEK+   R  EER+RAEAE RE+E +ALSL RALEE  EA+EE ERQN+ LRA++E L+S
Sbjct: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543

Query: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1578
            SKDDVGK+VHELE++ R  EQ   ++R Q+ ELEDEL A EDAKLRLEV +QA+K Q ER
Sbjct: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603

Query: 1579 DLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANK 1638
            DLQ RDE  EE++R L KQ+R+ E E ++ERKQR LAVA++KK+E +L++L+AQ+ +A +
Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663

Query: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELAS 1698
             ++E +KQLRK+QAQMK+  RE+EE R SR+EIF+Q++ESEK+LK LEAE+L+LQEELA+
Sbjct: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723

Query: 1699 SERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDR 1758
            S+RARR A+Q+RDE+ADE+ N    K+A+L+EKR+LE R+ QLEEELEEEQSN ELLNDR
Sbjct: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783

Query: 1759 FRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISA 1818
            +RK  LQV++L  EL+AERS + K+++ RQQLERQ +EL+ +L E +   +++ K TI+A
Sbjct: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843

Query: 1819 LEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANAR 1878
            LE+K+ Q EEQLEQE +ER  + KLVRR EK+LKE+ +QVE+ERR ADQ ++Q+EK N R
Sbjct: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903

Query: 1879 MKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSS 1938
            +KQLKRQLEEAEEEA+RA A RR+LQREL+D TE+ E ++REV+TL+NRLRR GP++F +
Sbjct: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR-GPLTF-T 1961

Query: 1939 SRSGRRQLHLE---GASLELSDDDTESKTSDVNETQPP 1973
            +R+ R+   LE    +  E  +    S  S   E  PP
Sbjct: 1962 TRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPP 1999


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 2588 bits (6707), Expect = 0.0
 Identities = 1314/1991 (65%), Positives = 1622/1991 (81%), Gaps = 49/1991 (2%)

Query: 27   QADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSK 86
            Q +WTA++LVW+PSE HGFEAA++++E  +E  VELAE+G++  + +D IQ+MNPPKFSK
Sbjct: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106

Query: 87   VEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK 146
             EDMAELTCLNEASVLHNL++RYYSGLIYTYSGLFCVVINPYK LPIY+E I+EMYRGKK
Sbjct: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166

Query: 147  RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRK 206
            RHE+PPH+YA++E AYR MLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS KGRK
Sbjct: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226

Query: 207  DHNIP--------GELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
            +  +P        GELERQLLQANPILE+FGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286

Query: 259  ANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIP 318
            ANIETYLLEKSRA+RQAKDE +FHIFYQLL GAGE LK+DLLLE  ++YRFL+NG    P
Sbjct: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346

Query: 319  GQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVA 378
            GQ+ ++ FQET+E++ ++GFSHEEI+SML++VS+VLQFGNI+ K+ERNTDQA+MP+NT A
Sbjct: 347  GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405

Query: 379  QKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVH 438
            QKLC LLG+ V +F+RA+LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYERLFRWLV 
Sbjct: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465

Query: 439  RINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
            R+N+ALDR+ RQGASF+GILDIAGFEIF+LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525

Query: 499  YQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQG 558
            YQREGI W F+DFGLDLQPCIDLIERPANPPG+LALLDEECWFPKATDK+FVEK+ QEQG
Sbjct: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585

Query: 559  SHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAEL 618
             H KFQ+PR L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDNVA LLHQS+DR  AE+
Sbjct: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645

Query: 619  WKD---------------------------------VDRIVGLDQVTGMTETAFGSAYKT 645
            WKD                                 V+ IVGL+QV+ + +   G   + 
Sbjct: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGG--RP 703

Query: 646  KKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVL 705
            ++GMFRTVGQLYKESL++LMATL NTNP+FVRCI+PNHEKRAGKL+P LVLDQLRCNGVL
Sbjct: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763

Query: 706  EGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQ 765
            EGIRICRQGFPNRI+FQEFRQRYEILTPNAIPKGFMDGKQACE+MI+ALELDPNLYR+GQ
Sbjct: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823

Query: 766  SKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAA 825
            SKIFFRAGVLA LEEERDLK+TDII+ FQA  RGYLAR+AF K+QQQ SAL+V+QRNCAA
Sbjct: 824  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883

Query: 826  YLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQL 885
            YLKLRHWQWWR+FTKVKPLLQVTRQ+E LQA+ +EL KV+E Q +   E+ E++ +  QL
Sbjct: 884  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943

Query: 886  LEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEK 945
             EE+  LAEQL+AE EL AEAEE R RLAA+KQELE ++ +LE+RV EEEE ++ +Q EK
Sbjct: 944  EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003

Query: 946  KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
            K++Q HIQ+LE  L+ EEGARQKLQLEKVT EAK+KK EE++LLLEDQNSK  KE+KL+E
Sbjct: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063

Query: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETT 1065
            DR+AE SSQ AEEEEK K+L K+R K E  I+D+E+RL+KEEK RQELEK KR+LDGE++
Sbjct: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123

Query: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1125
            +LQ+Q+ E Q + +EL+ QL +KEEELQ ALAR +DE   +   LK +RE QA +AE QE
Sbjct: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183

Query: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185
            D ESE+ +R KAEKQ+RDL EELEAL+ ELEDTLD+T AQQELR+KREQEV ELKK LEE
Sbjct: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243

Query: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1245
            ET+ HEA +Q++RQRH  AL EL+EQLEQA+R K   EK +  LE +  EL  E+  LQ 
Sbjct: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303

Query: 1246 VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK 1305
             + E E +R++L+ Q+QE+  +  +G+R R E AEK  + Q EL+NVS  L EAE K I+
Sbjct: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363

Query: 1306 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1365
             +K+ +S E+QL D QELLQEETR KL L SR+R +E E   L+EQ EEE  AR+   ++
Sbjct: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423

Query: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
            +   Q+QL++ +++ +++ G +E+ EEA+++  ++AEAL+QRL EK    D+LE+ + RL
Sbjct: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483

Query: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA 1485
            QQELDD T+DL+ QRQ+ S LEKKQ+KFDQLLAEEK+   R  EER+RAEAE RE+E +A
Sbjct: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543

Query: 1486 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR 1545
            LSL RALEE  EA+EE ERQN+ LRA++E L+SSKDDVGK+VHELE++ R  EQ   ++R
Sbjct: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603

Query: 1546 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL 1605
             Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQ RDE  EE++R L KQ+R+ E E 
Sbjct: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663

Query: 1606 EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665
            ++ERKQR LAVA++KK+E +L++L+AQ+ +A + ++E +KQLRK+QAQMK+  RE+EE R
Sbjct: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723

Query: 1666 ASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKS 1725
             SR+EIF+Q++ESEK+LK LEAE+L+LQEELA+S+RARR A+Q+RDE+ADE+ N    K+
Sbjct: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783

Query: 1726 ALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDN 1785
            A+L+EKR+LE R+ QLEEELEEEQSN ELLNDR+RK  LQV++L  EL+AERS + K+++
Sbjct: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843

Query: 1786 ARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVR 1845
             RQQLERQ +EL+ +L E +   +++ K TI+ALE+K+ Q EEQLEQE +ER  + KLVR
Sbjct: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903

Query: 1846 RTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQR 1905
            R EK+LKE+ +QVE+ERR ADQ ++Q+EK N R+KQLKRQLEEAEEEA+RA A RR+LQR
Sbjct: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963

Query: 1906 ELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLE---GASLELSDDDTES 1962
            EL+D TE+ E ++REV+TL+NRLRR GP++F ++R+ R+   LE    +  E  +    S
Sbjct: 1964 ELEDVTESAESMNREVTTLRNRLRR-GPLTF-TTRTVRQVFRLEEGVASDEEAEEAQPGS 2021

Query: 1963 KTSDVNETQPP 1973
              S   E  PP
Sbjct: 2022 GPSPEPEGSPP 2032


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 1422 bits (3682), Expect = 0.0
 Identities = 788/1908 (41%), Positives = 1177/1908 (61%), Gaps = 27/1908 (1%)

Query: 33   KKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAE 92
            KK V++P ++  F  A I    G +V  E  E GK   V +D + + NPPKF K+EDMA 
Sbjct: 34   KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92

Query: 93   LTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPP 152
            LT L+E +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+  ++  YRGKKR E PP
Sbjct: 93   LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152

Query: 153  HIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPG 212
            HI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+     K    PG
Sbjct: 153  HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212

Query: 213  E--LERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSR 270
            +  LE Q++QANP LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLEKSR
Sbjct: 213  KGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 272

Query: 271  AVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNN---YRFLSNGYIPIPGQQDKDNFQ 327
             + Q K ER +HIFYQ+LS     L   LL+   NN   Y F+S G   +    D +   
Sbjct: 273  VIFQLKAERDYHIFYQILSNKKPELLDMLLIT--NNPYDYAFISQGETTVASIDDAEELM 330

Query: 328  ETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGM 387
             T  A  ++GF+ EE  SM K+  +++ FGN+ FK ++  +QA       A K  +L+G+
Sbjct: 331  ATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGL 390

Query: 388  NVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRT 447
            N  +  + +  PR+KVG +YV K Q  +Q  +A  ALAKA YER+F W+V RIN  L+ T
Sbjct: 391  NSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE-T 449

Query: 448  KRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 507
            K+    FIG+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW 
Sbjct: 450  KQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 509

Query: 508  FIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQKP 566
            FIDFG+DLQ CIDLIE+P    G++++L+EEC FPKATD TF  KL     G  + FQKP
Sbjct: 510  FIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP 566

Query: 567  RQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDR 624
            R +K K  A F +IHYAG VDY    WL KN DPLN+ V  L  +SS + ++ L+ +   
Sbjct: 567  RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY-- 624

Query: 625  IVGLDQVTGMTETAFGSAYKTKKGM-FRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNH 683
              G D      E   G   K KKG  F+TV  L++E+L KLM  LR+T+P+FVRCIIPN 
Sbjct: 625  -AGAD---APIEKGKG---KAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNE 677

Query: 684  EKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMD 742
             K  G +D  LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL P AIP+G F+D
Sbjct: 678  TKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFID 737

Query: 743  GKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLA 802
             ++  E+++ +L++D N Y+ G +K+FF+AG+L  LEE RD +++ II   QA  RG LA
Sbjct: 738  SRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLA 797

Query: 803  RKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELL 862
            R  + K  ++  +L V+Q N  A++ +++W W +++ K+KPLL+   +E+E+ +  EE  
Sbjct: 798  RMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFT 857

Query: 863  KVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEE 922
            ++KE   K E   +E+E K   LL+EKN L  Q+QAE +  A+AEE   +L   K +LE 
Sbjct: 858  RLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917

Query: 923  ILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKK 982
             + ++  R+E+EEE N  L  +K+K++    +L+  +D+ E    K++ EK   E K+K 
Sbjct: 918  KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977

Query: 983  MEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEER 1042
            + EE+  L++  +K  KEKK +++   +    L  EE+K   L K + K E  + DLE  
Sbjct: 978  LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGS 1037

Query: 1043 LKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDE 1102
            L++E+K R +LE+AKRKL+G+    Q+ I +L+    +L  +L KK+ EL    AR +DE
Sbjct: 1038 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDE 1097

Query: 1103 TLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTT 1162
                +   K ++ELQA+I EL+E+ E+E+ +R K EK + DLS ELE +   LE+    T
Sbjct: 1098 QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1157

Query: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANL 1222
            + Q E+  KRE E  ++++ LEE T  HEA    +R++HA ++ EL EQ++  +R K  L
Sbjct: 1158 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1217

Query: 1223 EKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKA 1282
            EK K   + +  ++   ++ + + KA  E   + L+ Q+ E  +K  E  R   +L  + 
Sbjct: 1218 EKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277

Query: 1283 SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLE 1342
            +KLQ E   +S  L+E E    +  +   +   QL+D +  L+EE + K  L+  ++   
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337

Query: 1343 EEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKKKLLKDA 1401
             + + L+EQ EEE EA+  L++ +    S++A  + K + D +   E LEEAKKKL +  
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397

Query: 1402 EALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEK 1461
            +   + +E        LEKTK+RLQ E++DL VD++     A+ L+KKQ+ FD++LAE K
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWK 1457

Query: 1462 SISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKD 1521
                    E + ++ EAR   T+   L  A EE+LE  E F+R+NK L+ ++ DL     
Sbjct: 1458 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517

Query: 1522 DVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQ 1581
              GK +HELEK ++ LE +  E+++ LEE E  L+  E   LR ++    +KA+ ER L 
Sbjct: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577

Query: 1582 TRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARD 1641
             +DE+ E+ KR  ++ V  L+  L+ E + R  A+  KKKME DL ++E Q+  AN+   
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637

Query: 1642 EVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701
            E  KQ++ LQ+ +KD Q +L++A  + D++       E++   L+AE+ +L+  +  +ER
Sbjct: 1638 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697

Query: 1702 ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRK 1761
            +R+ AEQE  E ++ +    S  ++L+++K++++A ++QL+ E+EE         ++ +K
Sbjct: 1698 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK 1757

Query: 1762 TTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEA 1821
                   +  EL  E+  +   +  ++ +E+  K+L+ +L E E       K  +  LEA
Sbjct: 1758 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1817

Query: 1822 KIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQ 1881
            ++ +LE +LE E K  A + K +R++E+++KE+  Q E++R++  + ++ ++K   ++K 
Sbjct: 1818 RVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877

Query: 1882 LKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
             KRQ EEAEE+A    +  RK+Q ELD+A E  +    +V+ L+ + R
Sbjct: 1878 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925



 Score =  247 bits (631), Expect = 7e-65
 Identities = 232/1013 (22%), Positives = 473/1013 (46%), Gaps = 93/1013 (9%)

Query: 955  LEEQLDEEEG---ARQKLQLEKVTAEAKIKKMEEE---ILLLEDQNSKFIKEKKLMEDRI 1008
            LEE  DE       R + Q   V A  + KK+ E    +L+++     F+  K     ++
Sbjct: 773  LEEMRDERLSRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKL 832

Query: 1009 AECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQ 1068
                  L +  E+ K +A ++ +     + L+E L+K E  R+ELE+    L  E  DLQ
Sbjct: 833  YFKIKPLLKSAEREKEMASMKEE----FTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 888

Query: 1069 -------DQIAELQAQIDEL---KLQLAKKEEELQGALARGDDETLHKNNALKVVRELQA 1118
                   D +A+ + + D+L   K+QL  K +E+   L   D+E ++     K  R+L+ 
Sbjct: 889  LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLE--DEEEMNAELTAKK-RKLED 945

Query: 1119 QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL----EDTLDTTAAQQELRTKREQ 1174
            + +EL+ D +  + +  K EK+K     +++ L  E+    E     T  ++ L+   +Q
Sbjct: 946  ECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005

Query: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
             + +L+   ++     +A+++  +Q     +++L   LEQ K+ + +LE+ K+ LE D K
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQ-----VDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060

Query: 1235 ELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVST 1294
                 +  L+  K + + + KK D ++  L+A++ +   L  +L +K  +LQ  ++ +  
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120

Query: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
             LE       K  K  + L  +L++  E L+E        S +I   ++ +   Q+ + +
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT---SVQIEMNKKREAEFQKMRRD 1177

Query: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
             EEA    E    AL+ + AD+  ++ + +  ++ +++                      
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ---------------------- 1215

Query: 1415 YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRA 1474
              KLEK K+  + ELDD+T +++   +  +NLEK  +  +  + E +S     AEE  R+
Sbjct: 1216 --KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS----KAEETQRS 1269

Query: 1475 EAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1534
              +   +  K  +    L   L+ KE       QL           +D+ + + E  K+K
Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALI---SQLTRGKLTYTQQLEDLKRQLEEEVKAK 1326

Query: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLE-------VNMQAMKAQFERDLQTRDEQN 1587
             AL   ++  R   + L ++ +   +AK  L+         +   + ++E D   R E+ 
Sbjct: 1327 NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEEL 1386

Query: 1588 EEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQL 1647
            EE K+ L ++++E E  +E    + +    +K +++ +++DL   +E +N A   + K+ 
Sbjct: 1387 EEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQ 1446

Query: 1648 RKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSE 1700
            R     + +++++ EE+++       + + S+K+ +SL  E+ +L+       E L + +
Sbjct: 1447 RNFDKILAEWKQKYEESQS-------ELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1499

Query: 1701 RARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFR 1760
            R  ++ ++E  +L +++ +S      L   +++LEA   +L+  LEE ++++E    +  
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKIL 1559

Query: 1761 KTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQ-ELEGAVKSKFKA--TIS 1817
            +  L+ + + AE+  ER  A+K D   +Q +R +  +   LQ  L+   +S+ +A     
Sbjct: 1560 RAQLEFNQIKAEI--ERKLAEK-DEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKK 1616

Query: 1818 ALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANA 1877
             +E  + ++E QL    +  A A K V+  +  LK+  +Q++D  R  D  KE +     
Sbjct: 1617 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1676

Query: 1878 RMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
            R   L+ +LEE      +   SR+  ++EL + +E  + L  + ++L N+ ++
Sbjct: 1677 RNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1729



 Score =  222 bits (566), Expect = 2e-57
 Identities = 204/945 (21%), Positives = 429/945 (45%), Gaps = 117/945 (12%)

Query: 839  TKVKPLLQVTRQE--EELQAKDEEL-------LKVKEKQTKVEGELEEMERKHQQLLEEK 889
            TK K  LQ   Q+  ++LQA+++++       +K++++   +EG LE+ ++    L   K
Sbjct: 993  TKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1052

Query: 890  NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
              L   L+   E   + E  + +L  + ++ +  L+ L +R+E+E+     LQ + K++Q
Sbjct: 1053 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQ 1112

Query: 950  AHIQDLEEQLDEEEGARQKLQ---------LEKVTA-------------------EAKIK 981
            A I++LEE+L+ E  AR K++         LE+++                    EA+ +
Sbjct: 1113 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1172

Query: 982  KME---EEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD 1038
            KM    EE  L  +  +  +++K    D +AE   Q+   +   + L K +++ ++ + D
Sbjct: 1173 KMRRDLEEATLQHEATAAALRKKHA--DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDD 1230

Query: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
            +   +++  K +  LEK  R L+ +  + + +  E Q  +++L  Q AK + E  G L+R
Sbjct: 1231 VTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTE-NGELSR 1289

Query: 1099 GDDETLHKNNALKVVR-ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED 1157
              DE     + L   +     Q+ +L+   E E  ++N      +    + + L+ + E+
Sbjct: 1290 QLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349

Query: 1158 TLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217
              +  A  Q + +K   EVA+ +   E +      ++++ +++ A  L+E  E +E    
Sbjct: 1350 ETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNA 1409

Query: 1218 FKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277
              ++LEK K  L+ + ++L  +V+      A  + K++  D  + E   K  E       
Sbjct: 1410 KCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES 1469

Query: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337
              ++A  L  EL  +    EE+ +    F ++  +L+ ++ D  E L    +    L   
Sbjct: 1470 SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKV 1529

Query: 1338 IRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTI-ESLEEAKKK 1396
             +QLE EK  LQ   EE E + ++ E ++L  Q +    K +++  L    E +E+AK+ 
Sbjct: 1530 RKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN 1589

Query: 1397 LLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQL 1456
             L+  ++L   L+ +  + ++  + K +++ +L+++ + L H  ++A+  +K+ K    L
Sbjct: 1590 HLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 1649

Query: 1457 LAE----------------------EKSISARYAE-ERDRAEAEAREKETKALSLARALE 1493
            L +                      E+  +   AE E  RA  E  E+  K      A +
Sbjct: 1650 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL-----AEQ 1704

Query: 1494 EALEAKEEFE----------RQNKQLRADMEDLMSSKDDVG---KNVHE----------- 1529
            E +E  E  +           Q K++ AD+  L +  ++     +N  E           
Sbjct: 1705 ELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAM 1764

Query: 1530 --------------LEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQ 1575
                          LE+ K+ +EQ +++++ +L+E E    A +  K +L+  ++A   +
Sbjct: 1765 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQI--ALKGGKKQLQ-KLEARVRE 1821

Query: 1576 FERDLQTRDEQNEEKKRLLIK---QVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 1632
             E +L+   ++N E  + + K   +++EL  + E++RK          K+++ +K  + Q
Sbjct: 1822 LENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQ 1881

Query: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 1677
             E A +  +  + + RK+Q ++ + +   + A +  +++ A+S++
Sbjct: 1882 AEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRD 1926



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 82/323 (25%), Positives = 148/323 (45%), Gaps = 43/323 (13%)

Query: 860  ELLKVKEKQTKVEGELEEME-----------------RKHQQLLEEKNI-LAEQLQAETE 901
            E L+VK+K   +EG+L EME                 +  Q LL++  I L + ++A  +
Sbjct: 1610 EALRVKKK---MEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDD 1666

Query: 902  LF--------------AEAEEMRA---RLAAKKQELEEILHDLESRVEEEEERNQILQNE 944
            L               AE EE+RA   +    ++  E+ L +   RV+    +N  L N+
Sbjct: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1726

Query: 945  KKKMQAHIQDLEEQLDE--EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002
            KKKM A +  L+ +++E  +E    + + +K   +A +  M EE+   +D ++   + KK
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKK 1784

Query: 1003 LMEDRIAECSSQLAEEEEKA-KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD 1061
             ME  I +   +L E E+ A K   K   K E  + +LE  L+ E+K   E  K  RK +
Sbjct: 1785 NMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSE 1844

Query: 1062 GETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIA 1121
                +L  Q  E +  +  L+  + K + +++    + ++     N  L   R++Q ++ 
Sbjct: 1845 RRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELD 1904

Query: 1122 ELQEDFESEKASRNKAEKQKRDL 1144
            E +E  +  ++  NK   + RD+
Sbjct: 1905 EAEERADIAESQVNKLRAKSRDI 1927


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 1413 bits (3657), Expect = 0.0
 Identities = 774/1918 (40%), Positives = 1191/1918 (62%), Gaps = 26/1918 (1%)

Query: 25   ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
            A    + AK  V++   +  F   +I+   G +V V+  E G    V  D +  MNPPK+
Sbjct: 27   AQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKY 85

Query: 85   SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
             K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y   ++  YRG
Sbjct: 86   DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRG 145

Query: 145  KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204
            KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + 
Sbjct: 146  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205

Query: 205  RKDH----NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
            +K+      I G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+
Sbjct: 206  KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265

Query: 261  IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPG 319
            IETYLLEKSR V Q K ER++HIFYQ+ S     L   LL+     +Y F+S G I +  
Sbjct: 266  IETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS 325

Query: 320  QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379
              D++    T  A+ I+GF++EE +S+ K+  +V+ +GN+ FK+++  +QA      VA 
Sbjct: 326  IDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVAD 385

Query: 380  KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439
            K  +L  +N  +  +A+  PR+KVG +YV K QT EQ   AV ALAKA YE++F W+V R
Sbjct: 386  KAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVAR 445

Query: 440  INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
            IN+ LD TK+    FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 446  INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504

Query: 500  QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQG 558
            ++EGIEW FIDFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD +F  KL  Q  G
Sbjct: 505  KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLG 561

Query: 559  SHSKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616
              + FQKP+ +K KA+  F +IHYAG VDY    WL KN DPLN+ V  L  +S+ + +A
Sbjct: 562  KSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLA 621

Query: 617  ELWKDVDRIVGLDQVTGMTETAFGSAYK--TKKGM-FRTVGQLYKESLTKLMATLRNTNP 673
            +L+       G        E A G A K   KKG  F+TV  L++E+L KLM  LR+T+P
Sbjct: 622  QLFSGAQTAEG--------EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673

Query: 674  NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP 733
            +FVRCIIPN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L  
Sbjct: 674  HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733

Query: 734  NAIPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIF 792
            +AIP+G F+D K+A E+++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  +I  
Sbjct: 734  SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793

Query: 793  FQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEE 852
             QA CRG+LAR  + +  ++  A+  +Q N  +++ ++HW W ++F K+KPLL+    E+
Sbjct: 794  TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEK 853

Query: 853  ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRAR 912
            E+    EE  K+K++  K E + +E+E K   LL+EKN L  Q+QAE E  A+AEE   +
Sbjct: 854  EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913

Query: 913  LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLE 972
            L   K +LE  + ++  R E+EEE N  L  +K+K++    +L++ +D+ E    K++ E
Sbjct: 914  LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 973

Query: 973  KVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQ 1032
            K   E K+K + EE+  L++  +K  KEKK +++   +    L  EE+K   L K + K 
Sbjct: 974  KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033

Query: 1033 EVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL 1092
            E  + DLE  L++E+K R +LE+AKRKL+G+    Q+ I +++ +  +L  +L KKE E+
Sbjct: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093

Query: 1093 QGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK 1152
                ++ +DE        K ++ELQA+I EL+E+ E+E+ASR KAEKQ+ DLS ELE + 
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEIS 1153

Query: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQL 1212
              LE+    T+AQ E+  KRE E  ++++ LEE T  HEA    +R++HA ++ EL EQ+
Sbjct: 1154 ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQI 1213

Query: 1213 EQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272
            +  +R K  LEK K  ++ +  +LA  V+ + + K   E   + L+ Q+ EL +K  E  
Sbjct: 1214 DNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQ 1273

Query: 1273 RLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKL 1332
            RL  +L  +  +LQ E    S  L+E E    + ++   +   Q+++ +  L+EE + K 
Sbjct: 1274 RLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKN 1333

Query: 1333 NLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLE 1391
             L+  ++    + + L+EQ EEE+E++  L++ +    +++A  + K + D +   E LE
Sbjct: 1334 ALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE 1393

Query: 1392 EAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQK 1451
            EAKKKL +  +A  + +E        LEKTK RLQ E++DL +D++      + L+KKQ+
Sbjct: 1394 EAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQR 1453

Query: 1452 KFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1511
             FD++LAE K        E + ++ EAR   T+   +  A EE+L+  E  +R+NK L+ 
Sbjct: 1454 NFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513

Query: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571
            ++ DL     + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ +  
Sbjct: 1514 EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573

Query: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631
            +K++ +R +  +DE+ ++ KR  I+ V  +++ L+ E + R  A+  KKKME DL ++E 
Sbjct: 1574 VKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633

Query: 1632 QIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQ 1691
            Q+  AN+   E ++  R  Q  +KD Q  L++A  S++++  Q    E++   L+AEI +
Sbjct: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693

Query: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1751
            L+  L  +ER+R+ AEQE  + ++ +    +  ++L++ K++LE  I+Q++ E+E+    
Sbjct: 1694 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQE 1753

Query: 1752 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1811
                 ++ +K       +  EL  E+  +   +  ++ +E+  K+L+ +L E E      
Sbjct: 1754 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKG 1813

Query: 1812 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1871
             K  I  LEA++ +LE ++E E K  A A K +R+ E+++KE+  Q E++R++  + ++ 
Sbjct: 1814 GKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDL 1873

Query: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
            ++K  A++K  KRQ EEAEE++    A  RKLQ EL++A E  +    +V+ L+ + R
Sbjct: 1874 VDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931



 Score =  238 bits (606), Expect = 6e-62
 Identities = 206/943 (21%), Positives = 442/943 (46%), Gaps = 79/943 (8%)

Query: 1015 LAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI--- 1071
            L +  E  K +A ++ +       +++ L K E  R+ELE+    L  E  DLQ Q+   
Sbjct: 845  LLKSAETEKEMATMKEE----FQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900

Query: 1072 ----AELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF 1127
                A+ + + D+L     + E +++    R +DE           R+L+ + +EL++D 
Sbjct: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960

Query: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
            +  + +  K EK+K     +++ L  E+   LD T A+    TK ++ + E  +   ++ 
Sbjct: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKL---TKEKKALQEAHQQTLDDL 1016

Query: 1188 KNHEAQIQDMRQ---RHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQ 1244
            +  E ++  + +   +    +++L   LEQ K+ + +LE+ K+ LE D K     +  ++
Sbjct: 1017 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIE 1076

Query: 1245 QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGI 1304
              K + + K KK + ++  L +K+ +   L ++L +K  +LQ  ++ +   +E       
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136

Query: 1305 KFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEK 1364
            K  K  + L  +L++  E L+E         +   Q+E  K    +++ E ++ R++LE+
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAG------GATSAQIEMNK----KREAEFQKMRRDLEE 1186

Query: 1365 QVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNR 1424
              L  ++  A  +KK  D +                   L ++++       KLEK K+ 
Sbjct: 1187 ATLQHEATAATLRKKHADSVAE-----------------LGEQIDNLQRVKQKLEKEKSE 1229

Query: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1484
            ++ E+DDL  +++   +   NLEK  +  +  L+E KS         +   A+    +T+
Sbjct: 1230 MKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTE 1289

Query: 1485 ALSLARALEEA-------LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRAL 1537
            +   +R L+E           K+ F +Q ++L+  +E+ + +K+ +    H L+ S+   
Sbjct: 1290 SGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA---HALQSSRH-- 1344

Query: 1538 EQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ 1597
                + +R Q EE ++     + A  +    +   + ++E D   R E+ EE K+ L ++
Sbjct: 1345 --DCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402

Query: 1598 VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDY 1657
            ++  E  +E    + A    +K++++ +++DL   +E  N A   + K+ R     + ++
Sbjct: 1403 LQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462

Query: 1658 QRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSERARRHAEQER 1710
            +++ EE  A       + + S+K+ +SL  E+ +++       ++L + +R  ++ +QE 
Sbjct: 1463 KQKCEETHA-------ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEI 1515

Query: 1711 DELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLN 1770
             +L ++I         L   K+++E    +L+  LEE ++++E    +  +  L+++ + 
Sbjct: 1516 SDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVK 1575

Query: 1771 AELAAERSAAQKSDNARQQLERQNKELKAKLQE-LEGAVKSKFKATI--SALEAKIGQLE 1827
            +E+  +R  A+K D    QL+R +  +   +Q  L+  ++S+  A      +E  + ++E
Sbjct: 1576 SEV--DRKIAEK-DEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1632

Query: 1828 EQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLE 1887
             QL    +  A A +  R T+  LK+  + ++D  R  +  KEQ+     R   L+ ++E
Sbjct: 1633 IQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIE 1692

Query: 1888 EAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
            E      +   SR+  ++EL DA+E  + L  + ++L N  ++
Sbjct: 1693 ELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735



 Score =  231 bits (588), Expect = 7e-60
 Identities = 209/956 (21%), Positives = 437/956 (45%), Gaps = 112/956 (11%)

Query: 839  TKVKPLLQVTRQE--EELQAKDEEL-------LKVKEKQTKVEGELEEMERKHQQLLEEK 889
            TK K  LQ   Q+  ++LQA+++++       +K++++   +EG LE+ ++    L   K
Sbjct: 999  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058

Query: 890  NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
              L   L+   E   + E  + +L  K ++ E  + +L+S++E+E+     LQ + K++Q
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118

Query: 950  AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEE-----------EILLLEDQNSKFI 998
            A I++LEE+++ E  +R K + ++     +++++ E           +I + + + ++F 
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178

Query: 999  KEKKLME------------------DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLE 1040
            K ++ +E                  D +AE   Q+   +   + L K +++ ++ I DL 
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238

Query: 1041 ERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGD 1100
              ++   K +  LEK  R L+ + ++L+ +  E Q  I++L  Q  + + E      + D
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298

Query: 1101 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
            ++    +   +  +    QI EL+   E E  ++N      +    + + L+ + E+  +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358

Query: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220
            + A  Q   +K   EVA+ +   E +      ++++ +++ A  L+   E +E      A
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418

Query: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
            +LEK KQ L+ + ++L  +V+      A  + K++  D  + E   K  E         +
Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQK 1478

Query: 1281 KASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340
            +A  L  EL  +    EE+  +     ++  +L+ ++ D  E + E  ++   L    +Q
Sbjct: 1479 EARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1538

Query: 1341 LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTI-ESLEEAKKKLLK 1399
            +E+EK  LQ   EE E + ++ E ++L +Q +L   K +VD  +    E +++ K+  ++
Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIR 1598

Query: 1400 DAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAE 1459
              E++   L+ +  + +   + K +++ +L+++ + L+H  ++A+   +  +    +L +
Sbjct: 1599 IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKD 1658

Query: 1460 EKSISARYAEERDRAEAEAREK----ETKALSLARALEEALEAKEEFERQNKQLRADMED 1515
             +     + ++  R++ + +E+    E +A  L   +EE     E+ ER  K    ++ D
Sbjct: 1659 TQI----HLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLD 1714

Query: 1516 LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE--------DAKLRLE- 1566
                   +      L  +K+ LE  + +M+ ++E++  E +  E        DA +  E 
Sbjct: 1715 ASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEE 1774

Query: 1567 --------VNMQAMKAQFE---RDLQTRDEQNEE------KKRL--LIKQVRELEAELED 1607
                     +++ MK   E   +DLQ R ++ E+      KK++  L  +VRELE E+E 
Sbjct: 1775 LKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVES 1834

Query: 1608 ERKQRALAVASKKKMEIDLKDL----------------------------EAQIEAANKA 1639
            E+K+ A AV   +K E  +K+L                            + Q E A + 
Sbjct: 1835 EQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ 1894

Query: 1640 RDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEE 1695
             +  + + RKLQ        ELEEA    D   A+S+ ++ ++KS E     + EE
Sbjct: 1895 SNTNLAKFRKLQ-------HELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941



 Score =  175 bits (444), Expect = 3e-43
 Identities = 167/748 (22%), Positives = 351/748 (46%), Gaps = 64/748 (8%)

Query: 1234 KELACEVKVLQQVK---AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290
            KE+A   +  Q++K   A+SE KRK+L+ ++              V L ++ + LQ ++ 
Sbjct: 853  KEMATMKEEFQKIKDELAKSEAKRKELEEKM--------------VTLLKEKNDLQLQVQ 898

Query: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350
              +  L +AE++  +  K    LE+++++  E  ++E      L+++ R+LE+E + L++
Sbjct: 899  AEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKK 958

Query: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
              ++ E     +EK+  A ++++ +  +++     TI  L + KK L    EA  Q L++
Sbjct: 959  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL---QEAHQQTLDD 1015

Query: 1411 KALAYDK---LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISA 1465
                 DK   L K K +L+Q++DDL   L+ ++++  +LE+ ++K   D  LA+E  +  
Sbjct: 1016 LQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDI 1075

Query: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525
                E+ + + + ++KE +  +L   +E+      + +++ K+L+A +E+L    +    
Sbjct: 1076 E--NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERA 1133

Query: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
            +  + EK +  L +++EE+  +LEE      A  +   + E   Q M+    RDL+    
Sbjct: 1134 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR----RDLEEATL 1189

Query: 1586 QNEEKKRLLIKQ----VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARD 1641
            Q+E     L K+    V EL  ++++ ++ +      K +M++++ DL + +E  +KA+ 
Sbjct: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249

Query: 1642 EVIKQLRKLQAQM-------KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
             + K  R L+ Q+       ++ QR + +  A R  +  +S E  ++L   EA + QL  
Sbjct: 1250 NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLS- 1308

Query: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
                  R ++   Q+ +EL  ++      K+AL    +        L E+ EEEQ +   
Sbjct: 1309 ------RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAE 1362

Query: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKA 1814
            L     K   +V     +   E  A Q+++    +LE   K+L  +LQ  E  V++   A
Sbjct: 1363 LQRALSKANTEVAQWRTKY--ETDAIQRTE----ELEEAKKKLAQRLQAAEEHVEA-VNA 1415

Query: 1815 TISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEK 1874
              ++LE    +L+ ++E    +    N      +KK +          +   ++K++ E+
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF-------DKILAEWKQKCEE 1468

Query: 1875 ANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPI 1934
             +A ++  +++      E  +   +  +   +L+     N+ L +E+S L  ++  GG  
Sbjct: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGK- 1527

Query: 1935 SFSSSRSGRRQLHLEGASLELSDDDTES 1962
                    ++Q+  E   L+ + ++ E+
Sbjct: 1528 RIHELEKIKKQVEQEKCELQAALEEAEA 1555


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 1413 bits (3657), Expect = 0.0
 Identities = 774/1918 (40%), Positives = 1191/1918 (62%), Gaps = 26/1918 (1%)

Query: 25   ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
            A    + AK  V++   +  F   +I+   G +V V+  E G    V  D +  MNPPK+
Sbjct: 27   AQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKY 85

Query: 85   SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
             K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y   ++  YRG
Sbjct: 86   DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRG 145

Query: 145  KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204
            KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + 
Sbjct: 146  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205

Query: 205  RKDH----NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
            +K+      I G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+
Sbjct: 206  KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265

Query: 261  IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPG 319
            IETYLLEKSR V Q K ER++HIFYQ+ S     L   LL+     +Y F+S G I +  
Sbjct: 266  IETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVAS 325

Query: 320  QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379
              D++    T  A+ I+GF++EE +S+ K+  +V+ +GN+ FK+++  +QA      VA 
Sbjct: 326  IDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVAD 385

Query: 380  KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439
            K  +L  +N  +  +A+  PR+KVG +YV K QT EQ   AV ALAKA YE++F W+V R
Sbjct: 386  KAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVAR 445

Query: 440  INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
            IN+ LD TK+    FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 446  INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504

Query: 500  QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQG 558
            ++EGIEW FIDFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD +F  KL  Q  G
Sbjct: 505  KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLG 561

Query: 559  SHSKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616
              + FQKP+ +K KA+  F +IHYAG VDY    WL KN DPLN+ V  L  +S+ + +A
Sbjct: 562  KSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLA 621

Query: 617  ELWKDVDRIVGLDQVTGMTETAFGSAYK--TKKGM-FRTVGQLYKESLTKLMATLRNTNP 673
            +L+       G        E A G A K   KKG  F+TV  L++E+L KLM  LR+T+P
Sbjct: 622  QLFSGAQTAEG--------EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHP 673

Query: 674  NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP 733
            +FVRCIIPN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L  
Sbjct: 674  HFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNA 733

Query: 734  NAIPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIF 792
            +AIP+G F+D K+A E+++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  +I  
Sbjct: 734  SAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITR 793

Query: 793  FQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEE 852
             QA CRG+LAR  + +  ++  A+  +Q N  +++ ++HW W ++F K+KPLL+    E+
Sbjct: 794  TQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEK 853

Query: 853  ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRAR 912
            E+    EE  K+K++  K E + +E+E K   LL+EKN L  Q+QAE E  A+AEE   +
Sbjct: 854  EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913

Query: 913  LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLE 972
            L   K +LE  + ++  R E+EEE N  L  +K+K++    +L++ +D+ E    K++ E
Sbjct: 914  LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 973

Query: 973  KVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQ 1032
            K   E K+K + EE+  L++  +K  KEKK +++   +    L  EE+K   L K + K 
Sbjct: 974  KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033

Query: 1033 EVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEEL 1092
            E  + DLE  L++E+K R +LE+AKRKL+G+    Q+ I +++ +  +L  +L KKE E+
Sbjct: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093

Query: 1093 QGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK 1152
                ++ +DE        K ++ELQA+I EL+E+ E+E+ASR KAEKQ+ DLS ELE + 
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEIS 1153

Query: 1153 TELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQL 1212
              LE+    T+AQ E+  KRE E  ++++ LEE T  HEA    +R++HA ++ EL EQ+
Sbjct: 1154 ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQI 1213

Query: 1213 EQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272
            +  +R K  LEK K  ++ +  +LA  V+ + + K   E   + L+ Q+ EL +K  E  
Sbjct: 1214 DNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQ 1273

Query: 1273 RLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKL 1332
            RL  +L  +  +LQ E    S  L+E E    + ++   +   Q+++ +  L+EE + K 
Sbjct: 1274 RLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKN 1333

Query: 1333 NLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLE 1391
             L+  ++    + + L+EQ EEE+E++  L++ +    +++A  + K + D +   E LE
Sbjct: 1334 ALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE 1393

Query: 1392 EAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQK 1451
            EAKKKL +  +A  + +E        LEKTK RLQ E++DL +D++      + L+KKQ+
Sbjct: 1394 EAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQR 1453

Query: 1452 KFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1511
             FD++LAE K        E + ++ EAR   T+   +  A EE+L+  E  +R+NK L+ 
Sbjct: 1454 NFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513

Query: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571
            ++ DL     + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ +  
Sbjct: 1514 EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573

Query: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631
            +K++ +R +  +DE+ ++ KR  I+ V  +++ L+ E + R  A+  KKKME DL ++E 
Sbjct: 1574 VKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633

Query: 1632 QIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQ 1691
            Q+  AN+   E ++  R  Q  +KD Q  L++A  S++++  Q    E++   L+AEI +
Sbjct: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693

Query: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1751
            L+  L  +ER+R+ AEQE  + ++ +    +  ++L++ K++LE  I+Q++ E+E+    
Sbjct: 1694 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQE 1753

Query: 1752 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1811
                 ++ +K       +  EL  E+  +   +  ++ +E+  K+L+ +L E E      
Sbjct: 1754 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKG 1813

Query: 1812 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1871
             K  I  LEA++ +LE ++E E K  A A K +R+ E+++KE+  Q E++R++  + ++ 
Sbjct: 1814 GKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDL 1873

Query: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
            ++K  A++K  KRQ EEAEE++    A  RKLQ EL++A E  +    +V+ L+ + R
Sbjct: 1874 VDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931



 Score =  238 bits (606), Expect = 6e-62
 Identities = 206/943 (21%), Positives = 442/943 (46%), Gaps = 79/943 (8%)

Query: 1015 LAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI--- 1071
            L +  E  K +A ++ +       +++ L K E  R+ELE+    L  E  DLQ Q+   
Sbjct: 845  LLKSAETEKEMATMKEE----FQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900

Query: 1072 ----AELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF 1127
                A+ + + D+L     + E +++    R +DE           R+L+ + +EL++D 
Sbjct: 901  AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960

Query: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
            +  + +  K EK+K     +++ L  E+   LD T A+    TK ++ + E  +   ++ 
Sbjct: 961  DDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKL---TKEKKALQEAHQQTLDDL 1016

Query: 1188 KNHEAQIQDMRQ---RHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQ 1244
            +  E ++  + +   +    +++L   LEQ K+ + +LE+ K+ LE D K     +  ++
Sbjct: 1017 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIE 1076

Query: 1245 QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGI 1304
              K + + K KK + ++  L +K+ +   L ++L +K  +LQ  ++ +   +E       
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136

Query: 1305 KFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEK 1364
            K  K  + L  +L++  E L+E         +   Q+E  K    +++ E ++ R++LE+
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAG------GATSAQIEMNK----KREAEFQKMRRDLEE 1186

Query: 1365 QVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNR 1424
              L  ++  A  +KK  D +                   L ++++       KLEK K+ 
Sbjct: 1187 ATLQHEATAATLRKKHADSVAE-----------------LGEQIDNLQRVKQKLEKEKSE 1229

Query: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1484
            ++ E+DDL  +++   +   NLEK  +  +  L+E KS         +   A+    +T+
Sbjct: 1230 MKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTE 1289

Query: 1485 ALSLARALEEA-------LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRAL 1537
            +   +R L+E           K+ F +Q ++L+  +E+ + +K+ +    H L+ S+   
Sbjct: 1290 SGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA---HALQSSRH-- 1344

Query: 1538 EQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ 1597
                + +R Q EE ++     + A  +    +   + ++E D   R E+ EE K+ L ++
Sbjct: 1345 --DCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402

Query: 1598 VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDY 1657
            ++  E  +E    + A    +K++++ +++DL   +E  N A   + K+ R     + ++
Sbjct: 1403 LQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462

Query: 1658 QRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSERARRHAEQER 1710
            +++ EE  A       + + S+K+ +SL  E+ +++       ++L + +R  ++ +QE 
Sbjct: 1463 KQKCEETHA-------ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEI 1515

Query: 1711 DELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLN 1770
             +L ++I         L   K+++E    +L+  LEE ++++E    +  +  L+++ + 
Sbjct: 1516 SDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVK 1575

Query: 1771 AELAAERSAAQKSDNARQQLERQNKELKAKLQE-LEGAVKSKFKATI--SALEAKIGQLE 1827
            +E+  +R  A+K D    QL+R +  +   +Q  L+  ++S+  A      +E  + ++E
Sbjct: 1576 SEV--DRKIAEK-DEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1632

Query: 1828 EQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLE 1887
             QL    +  A A +  R T+  LK+  + ++D  R  +  KEQ+     R   L+ ++E
Sbjct: 1633 IQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIE 1692

Query: 1888 EAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
            E      +   SR+  ++EL DA+E  + L  + ++L N  ++
Sbjct: 1693 ELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735



 Score =  231 bits (588), Expect = 7e-60
 Identities = 209/956 (21%), Positives = 437/956 (45%), Gaps = 112/956 (11%)

Query: 839  TKVKPLLQVTRQE--EELQAKDEEL-------LKVKEKQTKVEGELEEMERKHQQLLEEK 889
            TK K  LQ   Q+  ++LQA+++++       +K++++   +EG LE+ ++    L   K
Sbjct: 999  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058

Query: 890  NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
              L   L+   E   + E  + +L  K ++ E  + +L+S++E+E+     LQ + K++Q
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118

Query: 950  AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEE-----------EILLLEDQNSKFI 998
            A I++LEE+++ E  +R K + ++     +++++ E           +I + + + ++F 
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178

Query: 999  KEKKLME------------------DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLE 1040
            K ++ +E                  D +AE   Q+   +   + L K +++ ++ I DL 
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238

Query: 1041 ERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGD 1100
              ++   K +  LEK  R L+ + ++L+ +  E Q  I++L  Q  + + E      + D
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298

Query: 1101 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
            ++    +   +  +    QI EL+   E E  ++N      +    + + L+ + E+  +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358

Query: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220
            + A  Q   +K   EVA+ +   E +      ++++ +++ A  L+   E +E      A
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418

Query: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
            +LEK KQ L+ + ++L  +V+      A  + K++  D  + E   K  E         +
Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQK 1478

Query: 1281 KASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340
            +A  L  EL  +    EE+  +     ++  +L+ ++ D  E + E  ++   L    +Q
Sbjct: 1479 EARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1538

Query: 1341 LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTI-ESLEEAKKKLLK 1399
            +E+EK  LQ   EE E + ++ E ++L +Q +L   K +VD  +    E +++ K+  ++
Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIR 1598

Query: 1400 DAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAE 1459
              E++   L+ +  + +   + K +++ +L+++ + L+H  ++A+   +  +    +L +
Sbjct: 1599 IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKD 1658

Query: 1460 EKSISARYAEERDRAEAEAREK----ETKALSLARALEEALEAKEEFERQNKQLRADMED 1515
             +     + ++  R++ + +E+    E +A  L   +EE     E+ ER  K    ++ D
Sbjct: 1659 TQI----HLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLD 1714

Query: 1516 LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE--------DAKLRLE- 1566
                   +      L  +K+ LE  + +M+ ++E++  E +  E        DA +  E 
Sbjct: 1715 ASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEE 1774

Query: 1567 --------VNMQAMKAQFE---RDLQTRDEQNEE------KKRL--LIKQVRELEAELED 1607
                     +++ MK   E   +DLQ R ++ E+      KK++  L  +VRELE E+E 
Sbjct: 1775 LKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVES 1834

Query: 1608 ERKQRALAVASKKKMEIDLKDL----------------------------EAQIEAANKA 1639
            E+K+ A AV   +K E  +K+L                            + Q E A + 
Sbjct: 1835 EQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ 1894

Query: 1640 RDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEE 1695
             +  + + RKLQ        ELEEA    D   A+S+ ++ ++KS E     + EE
Sbjct: 1895 SNTNLAKFRKLQ-------HELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941



 Score =  175 bits (444), Expect = 3e-43
 Identities = 167/748 (22%), Positives = 351/748 (46%), Gaps = 64/748 (8%)

Query: 1234 KELACEVKVLQQVK---AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290
            KE+A   +  Q++K   A+SE KRK+L+ ++              V L ++ + LQ ++ 
Sbjct: 853  KEMATMKEEFQKIKDELAKSEAKRKELEEKM--------------VTLLKEKNDLQLQVQ 898

Query: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350
              +  L +AE++  +  K    LE+++++  E  ++E      L+++ R+LE+E + L++
Sbjct: 899  AEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKK 958

Query: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
              ++ E     +EK+  A ++++ +  +++     TI  L + KK L    EA  Q L++
Sbjct: 959  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL---QEAHQQTLDD 1015

Query: 1411 KALAYDK---LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISA 1465
                 DK   L K K +L+Q++DDL   L+ ++++  +LE+ ++K   D  LA+E  +  
Sbjct: 1016 LQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDI 1075

Query: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525
                E+ + + + ++KE +  +L   +E+      + +++ K+L+A +E+L    +    
Sbjct: 1076 E--NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERA 1133

Query: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
            +  + EK +  L +++EE+  +LEE      A  +   + E   Q M+    RDL+    
Sbjct: 1134 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR----RDLEEATL 1189

Query: 1586 QNEEKKRLLIKQ----VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARD 1641
            Q+E     L K+    V EL  ++++ ++ +      K +M++++ DL + +E  +KA+ 
Sbjct: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249

Query: 1642 EVIKQLRKLQAQM-------KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
             + K  R L+ Q+       ++ QR + +  A R  +  +S E  ++L   EA + QL  
Sbjct: 1250 NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLS- 1308

Query: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
                  R ++   Q+ +EL  ++      K+AL    +        L E+ EEEQ +   
Sbjct: 1309 ------RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAE 1362

Query: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKA 1814
            L     K   +V     +   E  A Q+++    +LE   K+L  +LQ  E  V++   A
Sbjct: 1363 LQRALSKANTEVAQWRTKY--ETDAIQRTE----ELEEAKKKLAQRLQAAEEHVEA-VNA 1415

Query: 1815 TISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEK 1874
              ++LE    +L+ ++E    +    N      +KK +          +   ++K++ E+
Sbjct: 1416 KCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF-------DKILAEWKQKCEE 1468

Query: 1875 ANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPI 1934
             +A ++  +++      E  +   +  +   +L+     N+ L +E+S L  ++  GG  
Sbjct: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGK- 1527

Query: 1935 SFSSSRSGRRQLHLEGASLELSDDDTES 1962
                    ++Q+  E   L+ + ++ E+
Sbjct: 1528 RIHELEKIKKQVEQEKCELQAALEEAEA 1555


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 1407 bits (3643), Expect = 0.0
 Identities = 772/1918 (40%), Positives = 1188/1918 (61%), Gaps = 31/1918 (1%)

Query: 25   ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
            A    + AK  V++   +  +  ++I+ + G +V V+  E G    V +D +  MNPPK+
Sbjct: 29   AQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKY 87

Query: 85   SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
             K+EDMA +T L+E  VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y   ++  YRG
Sbjct: 88   DKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRG 147

Query: 145  KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204
            KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + 
Sbjct: 148  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 207

Query: 205  RKDHN--IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262
            +KD +  + G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IE
Sbjct: 208  KKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267

Query: 263  TYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPGQQ 321
            TYLLEKSR   Q K ER++HIFYQ+ S     L   LL+     +Y F+S G I +P   
Sbjct: 268  TYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSID 327

Query: 322  DKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKL 381
            D++    T  A+ I+GF+ EE +S+ K+  +V+ +GN+ FK+++  +QA      VA K 
Sbjct: 328  DQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKA 387

Query: 382  CHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRIN 441
             +L  +N  +  +A+  PR+KVG +YV K QT +Q   AV ALAKA YE++F W+V RIN
Sbjct: 388  AYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRIN 447

Query: 442  KALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQR 501
            + LD TK+    FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++
Sbjct: 448  QQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506

Query: 502  EGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQGSH 560
            EGIEW FIDFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD +F  KL  Q  G  
Sbjct: 507  EGIEWTFIDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563

Query: 561  SKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAEL 618
            + FQKP+ +K KA+  F +IHYAG VDY    WL KN DPLND V  L  +S+ + +A L
Sbjct: 564  ANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASL 623

Query: 619  WKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRC 678
            +            +   +++     K K   F+TV  L++E+L KLM  LR+T+P+FVRC
Sbjct: 624  FSTY--------ASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRC 675

Query: 679  IIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPK 738
            IIPN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L  +AIP+
Sbjct: 676  IIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPE 735

Query: 739  G-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVC 797
            G F+D K+A E+++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  II   QAVC
Sbjct: 736  GQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVC 795

Query: 798  RGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAK 857
            RG+L R  + K  Q+  AL  +Q N  A++ ++HW W ++F K+KPLL+    E+E+   
Sbjct: 796  RGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATM 855

Query: 858  DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK 917
             EE  K K++  K E + +E+E K   LL+EKN L  Q+Q+E +  A+AEE   +L   K
Sbjct: 856  KEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNK 915

Query: 918  QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE 977
             +LE  + ++  R EEEEE N  L  +K+K++    +L++ +D+ E    K++ EK   E
Sbjct: 916  IQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 975

Query: 978  AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037
             K+K + EE+  L++  +K  KEKK +++   +    L  EE+K   L K + K E  + 
Sbjct: 976  NKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVD 1035

Query: 1038 DLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALA 1097
            DLE  L++E+K R +LE+AKRKL+G+    Q+   +++    +L  +L KKE E+   ++
Sbjct: 1036 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLIS 1095

Query: 1098 RGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED 1157
            + +DE   +    K ++ELQA+I EL E+ E+E+ASR KAEKQ+ DLS ELE +   LE+
Sbjct: 1096 KIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1155

Query: 1158 TLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217
                T+AQ EL  KRE E  +L++ LEE T  HEA +  +R++HA ++ EL EQ++  +R
Sbjct: 1156 AGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQR 1215

Query: 1218 FKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277
             K  LEK K  L+ +  +L+   + + + K   E   + L+ QV EL  K  E  RL  +
Sbjct: 1216 VKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLIND 1275

Query: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337
            L  + ++LQ E    S  L+E +    + ++   +   Q+++ +  L+EET+ K  L+  
Sbjct: 1276 LTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHA 1335

Query: 1338 IRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKKK 1396
            ++    + + L+EQ EEE+E +  L++ +    S++A  + K + D +   E LEEAKKK
Sbjct: 1336 LQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1395

Query: 1397 LLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQL 1456
            L +  +   + +E        LEKTK RLQ E++DL +D++      + L+KKQ+ FD++
Sbjct: 1396 LAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKV 1455

Query: 1457 LAEEKSISARYAEERDRAEAEAREKETKALS-----LARALEEALEAKEEFERQNKQLRA 1511
            L+E K    +Y  E  +AE EA +KE+++LS     +    EE+L+  E   R+NK L+ 
Sbjct: 1456 LSEWKQ---KY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQ 1510

Query: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571
            ++ DL     + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ +  
Sbjct: 1511 EISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQ 1570

Query: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631
            +K++ +R +  +DE+ ++ KR   + V  +++ L+ E + R  A+  KKKME DL ++E 
Sbjct: 1571 VKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEI 1630

Query: 1632 QIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQ 1691
            Q+  AN+   E ++  R  Q  +K+ Q  L++A   ++++  Q    E++   L+AEI +
Sbjct: 1631 QLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEE 1690

Query: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1751
            L   L  +ER+R+ AEQE  + ++ +    +  ++L++ K++LE  ++QL+ E+EE    
Sbjct: 1691 LWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQE 1750

Query: 1752 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1811
                 ++ +K       +  EL  E+  +   +  ++ LE+  K+L+ +L E E      
Sbjct: 1751 SRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKG 1810

Query: 1812 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1871
             K  I  LEA++ +LE ++E E K  A A K +R+ E+++KE+  Q E++R++  + ++ 
Sbjct: 1811 GKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDL 1870

Query: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
            ++K  A++K  KRQ EEAEE++    +  RKLQ EL++A E  +    +V+ L+ + R
Sbjct: 1871 VDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928



 Score =  230 bits (587), Expect = 9e-60
 Identities = 216/946 (22%), Positives = 436/946 (46%), Gaps = 105/946 (11%)

Query: 839  TKVKPLLQVTRQE--EELQAKDEELLKVKEKQTKVE-------GELEEMERKHQQLLEEK 889
            +K K  LQ T Q+  ++LQA+++++  + + +TK+E       G LE+ ++    L   K
Sbjct: 996  SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055

Query: 890  NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
              L   L+   E   + E  + +L  K ++ E  + +L S++E+E+     LQ + K++Q
Sbjct: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115

Query: 950  AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIA 1009
            A I++L E+++ E  +R K + ++     +++++ E    LE+       + +L + R A
Sbjct: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGGATSAQVELNKKREA 1172

Query: 1010 ECSSQLAEEEEKAKN----LAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETT 1065
            E      + EE        +A +R K    +++L E++   ++ +Q+LEK K +L  ET 
Sbjct: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232

Query: 1066 DL---------------------QDQIAELQAQ-------IDELKLQLAKKEEELQGALA 1097
            DL                     +DQ++EL+ +       I++L  Q A+ + E      
Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292

Query: 1098 RGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED 1157
            + D++    +   +  +    QI EL+   E E  ++N      +    + + L+ + E+
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352

Query: 1158 TLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217
              +  A  Q   +K   EVA+ +   E +      ++++ +++ A  L+E  E +E    
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412

Query: 1218 FKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277
              A+LEK KQ L+ + ++L  +V+      A  + K++  D  + E   K  E  +  +E
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEE-TQAELE 1471

Query: 1278 LAEKASK-LQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
             ++K S+ L  EL  V  + EE+  +     ++  +L+ ++ D  E + E  +Q   L  
Sbjct: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531

Query: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTI-ESLEEAKK 1395
              +Q+E+EK  +Q   EE E + ++ E ++L +Q +L   K +VD  +    E +++ K+
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKR 1591

Query: 1396 KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASN---------- 1445
               +  E +   L+ +  + +   + K +++ +L+++ + L+H  ++A+           
Sbjct: 1592 NHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQG 1651

Query: 1446 -LEKKQKKFDQLLAEEKSISARYAEERDRA---EAEAREK----ETKALSLARALEEALE 1497
             L++ Q   D  L  ++ +  + A    RA   +AE  E     E    S   A +E L+
Sbjct: 1652 ILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLD 1711

Query: 1498 AKEEFE---RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDE 1554
            A E  +    QN  L    + L +    +   V E+ +  R  E++ ++  T    + +E
Sbjct: 1712 ASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEE 1771

Query: 1555 LQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE------KKRL--LIKQVRELEAELE 1606
            L+  +D    LE  M+    Q  +DLQ R ++ E+      KK++  L  +VRELE E+E
Sbjct: 1772 LKKEQDTSAHLE-RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1830

Query: 1607 DERKQRALAVASKKKMEIDLKDL----------------------------EAQIEAANK 1638
            +E+K+ A AV   +K E  +K+L                            + Q E A +
Sbjct: 1831 NEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEE 1890

Query: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKS 1684
              +  + + RKLQ ++++ +   + A +  +++  +S+E   K+ +
Sbjct: 1891 QSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISA 1936



 Score =  229 bits (583), Expect = 3e-59
 Identities = 208/949 (21%), Positives = 433/949 (45%), Gaps = 93/949 (9%)

Query: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
            K K L K    ++ M +  EE     +KT+ EL K++ K      +L++++  L  + ++
Sbjct: 838  KIKPLLKSAETEKEMATMKEEF----QKTKDELAKSEAK----RKELEEKMVTLLKEKND 889

Query: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
            L+LQ+  + + L  A  R   E L KN       +L+A+I E+ E  E E+    +   +
Sbjct: 890  LQLQVQSEADSLADAEERC--EQLIKNKI-----QLEAKIKEVTERAEEEEEINAELTAK 942

Query: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL-----------------KKAL 1183
            KR L +E   LK +++D   T A  ++ +   E +V  L                 KKAL
Sbjct: 943  KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002

Query: 1184 EEETKNHEAQIQDMRQRH---------ATALEE----LSEQLEQAKRFKANLEKNKQGLE 1230
            +E    H+  + D++             T LE+    L   LEQ K+ + +LE+ K+ LE
Sbjct: 1003 QE---THQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 1059

Query: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290
             D K        ++  K + + K +K + ++  L +K+ +   + ++L +K  +LQ  ++
Sbjct: 1060 GDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIE 1119

Query: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350
             +   +E       K  K  + L  +L++  E L+E        S+++   ++ +   Q+
Sbjct: 1120 ELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT---SAQVELNKKREAEFQK 1176

Query: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
             + + EEA    E  V AL+ + AD+  ++ + +  ++ +++                  
Sbjct: 1177 LRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQ------------------ 1218

Query: 1411 KALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEE 1470
                  KLEK K+ L+ E DDL+ + +   +   NLEK  +  +  ++E K+        
Sbjct: 1219 ------KLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRL 1272

Query: 1471 RDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHEL 1530
             +   A+    +T+A   +R L+E      +  R  +     +E+L    ++  K  + L
Sbjct: 1273 INDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNAL 1332

Query: 1531 EKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK 1590
              + ++     + +R Q EE ++     + A  +    +   + ++E D   R E+ EE 
Sbjct: 1333 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1392

Query: 1591 KRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKL 1650
            K+ L ++++E E  +E    + A    +K++++ +++DL   +E +N A   + K+ R  
Sbjct: 1393 KKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNF 1452

Query: 1651 QAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSERAR 1703
               + +++++ EE +A   E+ A  KES    +SL  E+ +++       ++L +  R  
Sbjct: 1453 DKVLSEWKQKYEETQA---ELEASQKES----RSLSTELFKVKNVYEESLDQLETLRREN 1505

Query: 1704 RHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTT 1763
            ++ +QE  +L ++I         L   K+++E    +++  LEE ++++E    +  +  
Sbjct: 1506 KNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQ 1565

Query: 1764 LQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKA--TISALEA 1821
            L+++ + +E+  +R  A+K +   Q      + ++     L+  ++S+  A      +E 
Sbjct: 1566 LELNQVKSEV--DRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEG 1623

Query: 1822 KIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQ 1881
             + ++E QL    +  A + +  R T+  LKE  + ++D  R  +  KEQ+     R   
Sbjct: 1624 DLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANL 1683

Query: 1882 LKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
            L+ ++EE      +   SR+  ++EL DA+E  + L  + ++L N  ++
Sbjct: 1684 LQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1732



 Score =  177 bits (450), Expect = 7e-44
 Identities = 159/741 (21%), Positives = 351/741 (47%), Gaps = 50/741 (6%)

Query: 1234 KELACEVKVLQQVK---AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290
            KE+A   +  Q+ K   A+SE KRK+L+ ++              V L ++ + LQ ++ 
Sbjct: 850  KEMATMKEEFQKTKDELAKSEAKRKELEEKM--------------VTLLKEKNDLQLQVQ 895

Query: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350
            + +  L +AE++  +  K+   LE+++++  E  +EE      L+++ R+LE+E + L++
Sbjct: 896  SEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955

Query: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
              ++ E     +EK+  A ++++ +  +++     TI  L + KK L +  +     L+ 
Sbjct: 956  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015

Query: 1411 KALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISARYA 1468
            +    + L K K +L+Q++DDL   L+ ++++  +LE+ ++K   D  LA+E ++     
Sbjct: 1016 EEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDME-- 1073

Query: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
             ++ + + +  +KE +  +L   +E+    + + +++ K+L+A +E+L       G+ + 
Sbjct: 1074 NDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEEL-------GEEIE 1126

Query: 1529 ELEKSKRALEQQVEEMRTQLEELEDELQ---ATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
                S+   E+Q  ++  +LEE+ + L+       A++ L    +A   +  RDL+    
Sbjct: 1127 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATL 1186

Query: 1586 QNEEKKRLLIKQVRELEAELEDE--RKQRALAVASKKKMEIDLK--DLEAQIEAANKARD 1641
            Q+E     L K+  +  AEL ++    QR      K+K E+ ++  DL +  EA +KA+ 
Sbjct: 1187 QHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKG 1246

Query: 1642 EVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701
             + K  R L+ Q+ + + + EE +   +++ AQ    + +      ++ +    ++   R
Sbjct: 1247 NLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSR 1306

Query: 1702 ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRK 1761
            +++ + Q+ +EL  ++      K+AL    +        L E+ EEEQ     L     K
Sbjct: 1307 SKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSK 1366

Query: 1762 TTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEA 1821
               +V     +   E  A Q+++    +LE   K+L  +LQE E  V++   A  ++LE 
Sbjct: 1367 ANSEVAQWRTKY--ETDAIQRTE----ELEEAKKKLAQRLQEAEEHVEA-VNAKCASLEK 1419

Query: 1822 KIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQ 1881
               +L+ ++E    +   +N      +KK +     + + ++  ++ + ++E +    + 
Sbjct: 1420 TKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRS 1479

Query: 1882 LKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRS 1941
            L  +L + +     +      L+RE       N+ L +E+S L  ++  GG         
Sbjct: 1480 LSTELFKVKNVYEESLDQLETLRRE-------NKNLQQEISDLTEQIAEGGK-QIHELEK 1531

Query: 1942 GRRQLHLEGASLELSDDDTES 1962
             ++Q+  E   ++ + ++ E+
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEA 1552



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 32/129 (24%), Positives = 65/129 (50%), Gaps = 19/129 (14%)

Query: 849  RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEE---------KNIL-----AE 894
            +Q ++L+A+  EL    E + K   E  +  RKH++ ++E         KN+L      +
Sbjct: 1813 KQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVD 1872

Query: 895  QLQAETELFA-EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953
            +LQA+ + +  +AEE   +  A   +  ++ H+LE    E EER  I +++  K++   +
Sbjct: 1873 KLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELE----EAEERADIAESQVNKLRVKSR 1928

Query: 954  DLEEQLDEE 962
            ++  ++  E
Sbjct: 1929 EVHTKISAE 1937


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 1405 bits (3637), Expect = 0.0
 Identities = 776/1925 (40%), Positives = 1185/1925 (61%), Gaps = 28/1925 (1%)

Query: 25   ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
            A    + AK   ++   +  +    IK  +  +V VE  +N +  +V  +D+  MNPPKF
Sbjct: 27   AQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVTVETEDN-RTLVVKPEDVYAMNPPKF 85

Query: 85   SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
             ++EDMA LT LNE +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+  ++E YRG
Sbjct: 86   DRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRG 145

Query: 145  KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK- 203
            KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++   
Sbjct: 146  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDL 205

Query: 204  -GRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262
              +KD  + G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IE
Sbjct: 206  AKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 265

Query: 263  TYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN--NYRFLSNGYIPIPGQ 320
            TYLLEKSR   Q K ER++HIFYQ+LS     L  +LLL   N  +Y F+S G I +   
Sbjct: 266  TYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL-IELLLITTNPYDYPFISQGEILVASI 324

Query: 321  QDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQK 380
             D +    T  A+ I+GF+ EE   + K+  +V+ +GN+ FK+++  +QA      VA K
Sbjct: 325  DDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 384

Query: 381  LCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRI 440
              +L+G+N  +  +A+  PR+KVG +YV K QT +Q   AV AL+K+ YE+LF W+V RI
Sbjct: 385  TAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRI 444

Query: 441  NKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQ 500
            N+ LD TK     FIG+LDIAGFEIFE NS EQLCIN+TNEKLQQ FNH MF+LEQEEY+
Sbjct: 445  NQQLD-TKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 503

Query: 501  REGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQGS 559
            +EGIEW FIDFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD +F  KL  Q  G 
Sbjct: 504  KEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGK 560

Query: 560  HSKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAE 617
             + FQKP+ +K +A+  F +IHYAG VDY    WL KN DPLN+ V  L  +SS+R +A 
Sbjct: 561  SNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAH 620

Query: 618  LWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVR 677
            L+         D  +G  + A     K K   F+TV  L++E+L KLM+ LR T+P+FVR
Sbjct: 621  LYAT---FATADADSGKKKVA-----KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVR 672

Query: 678  CIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIP 737
            CIIPN  K  G ++  LVL QLRCNGVLEGIRICR+GFPNRI++ +F+QRY +L  +AIP
Sbjct: 673  CIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIP 732

Query: 738  KG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAV 796
            +G F+D K+ACE+++ ++++D   Y+ G +K+FF+AG+L  LEE RD ++  +I   QAV
Sbjct: 733  EGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAV 792

Query: 797  CRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQA 856
            CRG+L R  F K  Q+  ++  +Q N  +++ ++HW W ++F K+KPLL+    E+E+  
Sbjct: 793  CRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMAT 852

Query: 857  KDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAK 916
              EE  K K++  K E + +E+E K   L++EKN L  Q+QAE+E   +AEE   +L   
Sbjct: 853  MKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKA 912

Query: 917  KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTA 976
            K +LE  + ++  R E+EEE N  L  +K+K++    +L++ +D+ E    K++ EK   
Sbjct: 913  KFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 972

Query: 977  EAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMI 1036
            E K+K + EE+  L++  +K  +EKK +++   +    L  EE+K  +L K ++K E  +
Sbjct: 973  ENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQV 1032

Query: 1037 SDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL 1096
             DLE  L++E+K R +LE+ KRKL+G+    Q+ I +L+    +L  +L KK+ E     
Sbjct: 1033 EDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQ 1092

Query: 1097 ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELE 1156
            ++ +DE        K ++ELQA+I EL+E+ E+E+A+R K EKQ+ D + ELE L   LE
Sbjct: 1093 SKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLE 1152

Query: 1157 DTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK 1216
            +    T+ Q EL  KRE E  +L++ LEE T  HEA +  +R++HA ++ EL EQ++  +
Sbjct: 1153 EAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQ 1212

Query: 1217 RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
            R K  LEK K   + +  +L+  ++ + + KA  E   + L+ Q+ E   K  E  R   
Sbjct: 1213 RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS 1272

Query: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
            EL  + S+LQ E   +S  LEE E    + ++   +   Q ++ +  L+EE + K  L+ 
Sbjct: 1273 ELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAH 1332

Query: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKK 1395
             ++    + + L+EQ EEE+E +  L++ +    S++A  + K + D +   E LEEAKK
Sbjct: 1333 ALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1392

Query: 1396 KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQ 1455
            KL +  +   +++E        LEKTK RLQ E++DL VD++    +A+ L+KKQ+ FD+
Sbjct: 1393 KLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDK 1452

Query: 1456 LLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED 1515
            +LAE K+       E + +  E+R   T+   L  A EEAL+  E  +R+NK L  ++ D
Sbjct: 1453 VLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIAD 1512

Query: 1516 LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQ 1575
            L     + GK +HELEKS++ +E +  +++  LEE E  L+  E   LR+++ +  +K++
Sbjct: 1513 LTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSE 1572

Query: 1576 FERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEA 1635
             +R +  +DE+ E+ KR   + V  +++ L+ E + R  A+  KKKME DL ++E Q+  
Sbjct: 1573 IDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSH 1632

Query: 1636 ANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEE 1695
            AN+   E +K LR +Q Q+KD Q  L++A   ++++  Q    E++   L+AE+ +L+  
Sbjct: 1633 ANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRAT 1692

Query: 1696 LASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELL 1755
            L  +ERAR+ AEQE  +  + +    +  ++L+  K++LE  + QL+ E+E+   +    
Sbjct: 1693 LEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNA 1752

Query: 1756 NDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKAT 1815
             ++ +K       +  EL  E+  +   +  ++ LE+  K+L+ +L E E       K  
Sbjct: 1753 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ 1812

Query: 1816 ISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKA 1875
            I  LE +I +LE +LE E K+   + K +R+ E+++KE+  Q E++R++  + ++ ++K 
Sbjct: 1813 IQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKL 1872

Query: 1876 NARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPIS 1935
              ++K  KRQ EEA+E+A       RK Q EL++A E  +    +V+ L+ + R      
Sbjct: 1873 QVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR-----D 1927

Query: 1936 FSSSR 1940
            F+SSR
Sbjct: 1928 FTSSR 1932



 Score =  128 bits (322), Expect = 5e-29
 Identities = 121/542 (22%), Positives = 246/542 (45%), Gaps = 55/542 (10%)

Query: 849  RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETEL-FAEAE 907
            + ++ LQ + E+L+   E+   +   L++ +R   ++L E     E+ QAE E    E+ 
Sbjct: 1417 KTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESR 1476

Query: 908  EMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE----- 962
             +   L   K   EE L  LE+           ++ E K ++  I DL EQ+ E      
Sbjct: 1477 SLSTELFKLKNAYEEALDQLET-----------VKRENKNLEQEIADLTEQIAENGKTIH 1525

Query: 963  --EGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
              E +R++++LEK   +  +++ E     LE + +K ++ +  +    +E   ++AE++E
Sbjct: 1526 ELEKSRKQIELEKADIQLALEEAEAA---LEHEEAKILRIQLELTQVKSEIDRKIAEKDE 1582

Query: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
            + + L   RN Q   +  ++  L  E ++R E  + K+K++G+  +++ Q++    Q  E
Sbjct: 1583 EIEQLK--RNYQRT-VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAE 1639

Query: 1081 LKLQLAKKEEELQGALARGDD-----ETLHKNNALKVVRE--LQAQIAELQEDFESEKAS 1133
                L   + +L+      DD     E L +  A+   R   LQA++ EL+   E  + +
Sbjct: 1640 TLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA 1699

Query: 1134 RNKAEKQ---------------------KRDLSEELEALKTELEDTLDTTAAQQELRTKR 1172
            R  AE++                     K+ L  +L  L++E+ED        +E   K 
Sbjct: 1700 RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKA 1759

Query: 1173 EQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK-QGLET 1231
              + A + + L++E ++  A ++ M++     +++L  +L++A++      K + Q LET
Sbjct: 1760 ITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818

Query: 1232 DNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDN 1291
              +EL  E++  Q+   ES    +K + +V+EL  +  E  +  + L +   KLQ ++ +
Sbjct: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878

Query: 1292 VSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQ 1351
                 EEA+++           + +L++ +E       Q   L ++ R     +  + E 
Sbjct: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHES 1938

Query: 1352 QE 1353
            +E
Sbjct: 1939 EE 1940



 Score =  111 bits (277), Expect = 8e-24
 Identities = 98/466 (21%), Positives = 207/466 (44%), Gaps = 39/466 (8%)

Query: 1507 KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE 1566
            K++    E+   +KD++ K+    E  ++ LE+++  +  +  +L+ ++QA  +  L  E
Sbjct: 848  KEMATMKEEFQKTKDELAKS----EAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE 903

Query: 1567 VNM-QAMKAQFE-----RDLQTRDEQNEE-------KKRLLIKQVRELEAELEDERKQRA 1613
                Q +KA+F+     +++  R E  EE       KKR L  +  EL+ +++D     A
Sbjct: 904  ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 963

Query: 1614 LAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFA 1673
                 K   E  +K+L  ++   ++    + K  R+ +A  + +Q+ L++ +A  D++ +
Sbjct: 964  KVEKEKHATENKVKNLTEELSGLDET---IAKLTREKKALQEAHQQALDDLQAEEDKVNS 1020

Query: 1674 QSKES---EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDE 1730
             +K     E++++ LE+ + Q ++     ER +R  E +     + I +  + K  L + 
Sbjct: 1021 LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080

Query: 1731 KRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQL 1790
             ++ +    QL+ ++E+EQ+       + ++   +++ L  E+ AER+   K++  R   
Sbjct: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140

Query: 1791 ERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK- 1849
             R+ +EL  +L+E  G   ++ +      EA+  +L   LE+   +  A    +R+    
Sbjct: 1141 ARELEELSERLEEAGGVTSTQIELN-KKREAEFLKLRRDLEEATLQHEAMVAALRKKHAD 1199

Query: 1850 ----------KLKEIFMQVEDERRH----ADQYKEQMEKANARMKQLKRQLEEAEEEATR 1895
                       L+ +  ++E E+       D     ME  +     L++     E++ + 
Sbjct: 1200 SVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSE 1259

Query: 1896 ANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRS 1941
            A     ++QR L + T     L  E   L  +L     I    SRS
Sbjct: 1260 ARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRS 1305


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 1403 bits (3632), Expect = 0.0
 Identities = 774/1904 (40%), Positives = 1175/1904 (61%), Gaps = 25/1904 (1%)

Query: 37   WIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCL 96
            ++P ++  F  A I    G +V+ E  ENGK   V +D + + NPPKF K+EDMA LT L
Sbjct: 38   FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96

Query: 97   NEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYA 156
            +E +VL NLK+RY + +IYTYSGLFCV +NPYK LP+Y+  ++  YRGKKR E PPHI++
Sbjct: 97   HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156

Query: 157  ISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS-SHKGRKDHNIP--GE 213
            IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+   +G+KD+     G 
Sbjct: 157  ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGT 216

Query: 214  LERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVR 273
            LE Q++QANP LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLEKSR + 
Sbjct: 217  LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIF 276

Query: 274  QAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN--NYRFLSNGYIPIPGQQDKDNFQETME 331
            Q K ER +HIFYQ+LS     L  D+LL   N  +Y F+S G + +    D +    T  
Sbjct: 277  QLKAERNYHIFYQILSNKKPELL-DMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDS 335

Query: 332  AMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVME 391
            A  ++GF+ EE   + K+  +++ +GN+ FK+++  +QA       A K  +L+G+N  +
Sbjct: 336  AFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSAD 395

Query: 392  FTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQG 451
              + +  PR+KVG +YV K Q+ +Q  +++ ALAKA YE++F W+V RIN  L+ TK+  
Sbjct: 396  LLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE-TKQPR 454

Query: 452  ASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 511
              FIG+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW FIDF
Sbjct: 455  QYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDF 514

Query: 512  GLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQKPRQLK 570
            G+DLQ CIDLIE+P    G++++L+EEC FPKATD TF  KL     G  + FQKPR +K
Sbjct: 515  GMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK 571

Query: 571  DK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGL 628
             K  A F +IHYAG VDY    WL KN DPLN+ V  L  +SS + +A L+         
Sbjct: 572  GKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY------ 625

Query: 629  DQVTGMTETAFGSAYKTKKGM-FRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRA 687
               T  T  +  S    KKG  F+TV  L++E+L KLM  LR T+P+FVRCIIPN  K  
Sbjct: 626  --ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAP 683

Query: 688  GKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMDGKQA 746
            G +D  LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL P AIP+G F+D ++ 
Sbjct: 684  GVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKG 743

Query: 747  CERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAF 806
             E+++ +L++D N Y+ G +K+FF+AG+L  LEE RD +++ II   QA  RG L R  F
Sbjct: 744  TEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEF 803

Query: 807  AKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKE 866
             K  ++  AL V+Q N  A++ +++W W +++ K+KPLL+    E+E+    EE  ++KE
Sbjct: 804  KKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKE 863

Query: 867  KQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHD 926
               K E   +E+E K   LL+EKN L  Q+QAE +   +AEE   +L   K +LE  + +
Sbjct: 864  TLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKE 923

Query: 927  LESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEE 986
            +  R+E+EEE N  L  +K+K++    +L++ +D+ E    K++ EK   E K+K + EE
Sbjct: 924  MNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 983

Query: 987  ILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKE 1046
            +  L++  +K  KEKK +++   +    L  EE+K  +L+K + K E  + DLE  L++E
Sbjct: 984  MAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQE 1043

Query: 1047 EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHK 1106
            +K R +LE+AKRKL+G+    Q+ I +L+    +L+ +L KKE ++    ++ +DE +  
Sbjct: 1044 KKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLA 1103

Query: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166
                K ++E QA+I EL+E+ E+E+ +R K EK + DLS ELE +   LE+    T+ Q 
Sbjct: 1104 LQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQI 1163

Query: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
            E+  KRE E  ++++ LEE T  HEA    +R++HA ++ EL EQ++  +R K  LEK K
Sbjct: 1164 EMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEK 1223

Query: 1227 QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQ 1286
               + +  ++   ++ + + KA  E   + L+ Q  E   K+ E  R   +   + +KLQ
Sbjct: 1224 SEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQ 1283

Query: 1287 NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN 1346
             E   ++  LEE E    +  +   S   Q++D +  L+EE + K  L+  ++    + +
Sbjct: 1284 TENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCD 1343

Query: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKKKLLKDAEALS 1405
             L+EQ EEE EA+  L++ +    S++A  + K + D +   E LEEAKKKL +  +   
Sbjct: 1344 LLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1403

Query: 1406 QRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISA 1465
            + +E        LEKTK+RLQ E++DL VD++     A+ L+KKQ+ FD++LAE K    
Sbjct: 1404 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE 1463

Query: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525
                E + ++ EAR   T+   L  A EE+LE  E F+R+NK L+ ++ DL     + GK
Sbjct: 1464 ESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGK 1523

Query: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
            NVHELEK ++ LE +  E+++ LEE E  L+  E   LR ++    +KA+ ER L  +DE
Sbjct: 1524 NVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDE 1583

Query: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645
            + E+ KR   + V  L+  L+ E + R   +  KKKME DL ++E Q+  AN+   E  K
Sbjct: 1584 EMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQK 1643

Query: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705
            Q++ LQ+ +KD Q +L++A  + D++       E++   L+AE+ +L+  +  +ER+R+ 
Sbjct: 1644 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 1703

Query: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765
            AEQE  E ++ +    S  ++L+++K+++E+ + QL+ E+EE         ++ +K    
Sbjct: 1704 AEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITD 1763

Query: 1766 VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ 1825
               +  EL  E+  +   +  ++ +E+  K+L+ +L E E       K  +  LEA++ +
Sbjct: 1764 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRE 1823

Query: 1826 LEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQ 1885
            LE +LE E K  A + K +R++E+++KE+  Q E+++++  + ++ ++K   ++K  KRQ
Sbjct: 1824 LEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQ 1883

Query: 1886 LEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
             EEAEE+A    +  RK+Q ELD+A E  +    +V+ L+ + R
Sbjct: 1884 AEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927



 Score =  241 bits (616), Expect = 4e-63
 Identities = 207/950 (21%), Positives = 437/950 (46%), Gaps = 49/950 (5%)

Query: 839  TKVKPLLQVTRQE--EELQAKDEEL-------LKVKEKQTKVEGELEEMERKHQQLLEEK 889
            TK K  LQ   Q+  ++LQ +++++       +K++++   +EG LE+ ++    L   K
Sbjct: 995  TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK 1054

Query: 890  NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
              L   L+   E   + E  + +L  K ++ E  ++   S++E+E+     LQ + K+ Q
Sbjct: 1055 RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQ 1114

Query: 950  AHIQDLEEQLDEEEGARQKLQ---------LEKVTA-------------------EAKIK 981
            A I++LEE+L+ E  AR K++         LE+++                    EA+ +
Sbjct: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1174

Query: 982  KME---EEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD 1038
            KM    EE  L  +  +  +++K    D +AE   Q+   +   + L K +++ ++ + D
Sbjct: 1175 KMRRDLEEATLQHEATAAALRKKHA--DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDD 1232

Query: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
            +   +++  K +  LEK  R L+ +  + + ++ E Q  +++   Q AK + E  G LAR
Sbjct: 1233 VTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTE-NGELAR 1291

Query: 1099 GDDETLHKNNALKVVR-ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED 1157
              +E     + L   +     Q+ +L+   E E  ++N      +    + + L+ + E+
Sbjct: 1292 QLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEE 1351

Query: 1158 TLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217
              +  A  Q + +K   EVA+ +   E +      ++++ +++ A  L++  E +E    
Sbjct: 1352 ETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNA 1411

Query: 1218 FKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277
              ++LEK K  L+ + ++L  +V+      A  + K++  D  + E   K  E       
Sbjct: 1412 KCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES 1471

Query: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337
              ++A  L  EL  +    EE+ +    F ++  +L+ ++ D  E L E  +    L   
Sbjct: 1472 SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKV 1531

Query: 1338 IRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTI-ESLEEAKKK 1396
             +QLE EK  LQ   EE E + ++ E ++L  Q +    K +++  L    E +E+AK+ 
Sbjct: 1532 RKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN 1591

Query: 1397 LLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQL 1456
              +  ++L   L+ +  + +++ + K +++ +L+++ + L H  ++A+  +K+ K    L
Sbjct: 1592 HQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 1651

Query: 1457 LAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDL 1516
            L + +          D  +      E +   L   LEE     E+ ER  K    ++ + 
Sbjct: 1652 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIET 1711

Query: 1517 MSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQF 1576
                  +      L   K+ +E  + ++++++EE   E +  E+ K +  +   AM A+ 
Sbjct: 1712 SERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEE-KAKKAITDAAMMAEE 1770

Query: 1577 ERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK--KMEIDLKDLEAQIE 1634
             +  Q      E  K+ + + +++L+  L DE +Q AL    K+  K+E  +++LE ++E
Sbjct: 1771 LKKEQDTSAHLERMKKNMEQTIKDLQHRL-DEAEQIALKGGKKQLQKLEARVRELEGELE 1829

Query: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
            A  K   E +K +RK + ++K+   + EE + +   +     + + K+K+ + +  + +E
Sbjct: 1830 AEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1889

Query: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEE 1744
            +  ++    R  + E DE  +    + S  + L  + R + A+    +EE
Sbjct: 1890 QANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE 1939



 Score =  236 bits (603), Expect = 1e-61
 Identities = 223/1008 (22%), Positives = 463/1008 (45%), Gaps = 83/1008 (8%)

Query: 955  LEEQLDEEEG-------ARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR 1007
            LEE  DE          A+ + QL ++  + KI +  + +L+++     F+  K     +
Sbjct: 775  LEEMRDERLSRIITRMQAQARGQLMRIEFK-KIVERRDALLVIQWNIRAFMGVKNWPWMK 833

Query: 1008 IAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDL 1067
            +      L +  E  K +A ++ +       ++E L+K E  R+ELE+    L  E  DL
Sbjct: 834  LYFKIKPLLKSAETEKEMATMKEE----FGRIKETLEKSEARRKELEEKMVSLLQEKNDL 889

Query: 1068 Q-------DQIAELQAQIDEL---KLQLAKKEEELQGALARGDDETLHKNNALKVVRELQ 1117
            Q       D + + + + D+L   K+QL  K +E+   L   D+E ++     K  R+L+
Sbjct: 890  QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLE--DEEEMNAELTAKK-RKLE 946

Query: 1118 AQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL----EDTLDTTAAQQELRTKRE 1173
             + +EL++D +  + +  K EK+K     +++ L  E+    E     T  ++ L+   +
Sbjct: 947  DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQ 1006

Query: 1174 QEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDN 1233
            Q + +L+  +EE+  N    +   + +    +++L   LEQ K+ + +LE+ K+ LE D 
Sbjct: 1007 QALDDLQ--VEEDKVN---SLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1061

Query: 1234 KELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVS 1293
            K     +  L+  K + E K KK +  + + ++K+ +   L ++L +K  + Q  ++ + 
Sbjct: 1062 KLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELE 1121

Query: 1294 TLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQE 1353
              LE       K  K  + L  +L++  E L+E        S +I   ++ +   Q+ + 
Sbjct: 1122 EELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT---SVQIEMNKKREAEFQKMRR 1178

Query: 1354 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKAL 1413
            + EEA    E    AL+ + AD+  ++ + +  ++ +++                     
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ--------------------- 1217

Query: 1414 AYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDR 1473
               KLEK K+  + ELDD+T +++   +  +NLEK  +  +   A E  +    A+    
Sbjct: 1218 ---KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQ-ANEYRVKLEEAQRSLN 1273

Query: 1474 AEAEAREK-ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532
                 R K +T+   LAR LEE      +  R        MEDL    ++ GK  + L  
Sbjct: 1274 DFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAH 1333

Query: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592
            + ++     + +R Q EE  +     +    +    +   + ++E D   R E+ EE K+
Sbjct: 1334 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK 1393

Query: 1593 LLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652
             L +++++ E  +E    + +    +K +++ +++DL   +E +N A   + K+ R    
Sbjct: 1394 KLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 1453

Query: 1653 QMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSERARRH 1705
             + +++++ EE+++       + + S+K+ +SL  E+ +L+       E L + +R  ++
Sbjct: 1454 ILAEWKQKYEESQS-------ELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKN 1506

Query: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765
             ++E  +L +++         L   +++LE    +L+  LEE ++++E    +  +  L+
Sbjct: 1507 LQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLE 1566

Query: 1766 VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQ---ELEGAVKSKFKATISALEAK 1822
             + + AE+  ER  A+K D   +Q +R ++ +   LQ   + E   +++       +E  
Sbjct: 1567 FNQIKAEI--ERKLAEK-DEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGD 1623

Query: 1823 IGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQL 1882
            + ++E QL    +  A A K V+  +  LK+  +Q++D  R  D  KE +     R   L
Sbjct: 1624 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1683

Query: 1883 KRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
            + +LEE      +   SR+  ++EL + +E  + L  + ++L N+ ++
Sbjct: 1684 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1731



 Score =  170 bits (431), Expect = 1e-41
 Identities = 168/746 (22%), Positives = 341/746 (45%), Gaps = 60/746 (8%)

Query: 1234 KELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVS 1293
            KE+A   +   ++K   E    K +A+ +EL  K+       V L ++ + LQ ++    
Sbjct: 849  KEMATMKEEFGRIKETLE----KSEARRKELEEKM-------VSLLQEKNDLQLQVQAEQ 897

Query: 1294 TLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQE 1353
              L +AE++  +  K+   LE+++++  E L++E      L+++ R+LE+E + L++  +
Sbjct: 898  DNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDID 957

Query: 1354 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALS----QRLE 1409
            + E     +EK+  A       T+ KV +    +  L+E   KL K+ +AL     Q L+
Sbjct: 958  DLELTLAKVEKEKHA-------TENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALD 1010

Query: 1410 EKALAYDK---LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISAR 1466
            +  +  DK   L K+K +L+Q++DDL   L+ +++V  +LE+ ++K +  L   +     
Sbjct: 1011 DLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMD 1070

Query: 1467 YAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKN 1526
               ++ + E + ++KE         +E+      + +++ K+ +A +E+L    +     
Sbjct: 1071 LENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTA 1130

Query: 1527 VHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQ 1586
              ++EK +  L +++EE+  +LEE         +   + E   Q M+    RDL+    Q
Sbjct: 1131 RAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMR----RDLEEATLQ 1186

Query: 1587 NEEKKRLLIKQ----VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDE 1642
            +E     L K+    V EL  ++++ ++ +      K + +++L D+ + +E   KA+  
Sbjct: 1187 HEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN 1246

Query: 1643 VIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERA 1702
            + K  R L+ Q  +Y+ +LEEA+ S ++   Q  + + +   L  ++ + +  ++   R 
Sbjct: 1247 LEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRG 1306

Query: 1703 RRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKT 1762
            +    Q+ ++L  ++      K+AL    +        L E+ EEE      L     K 
Sbjct: 1307 KLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1366

Query: 1763 TLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVK------SKFKATI 1816
              +V     +   E  A Q+++    +LE   K+L  +LQ+ E AV+      S  + T 
Sbjct: 1367 NSEVAQWRTKY--ETDAIQRTE----ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTK 1420

Query: 1817 SALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKAN 1876
              L+ +I  L   +E+     AA +K  R  +K L E   + E+ +   +  +++    +
Sbjct: 1421 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1480

Query: 1877 ARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISF 1936
              + +LK   EE+ E               L+     N+ L  E+S L  +L  GG  + 
Sbjct: 1481 TELFKLKNAYEESLEH--------------LETFKRENKNLQEEISDLTEQLGEGGK-NV 1525

Query: 1937 SSSRSGRRQLHLEGASLELSDDDTES 1962
                  R+QL +E   L+ + ++ E+
Sbjct: 1526 HELEKVRKQLEVEKLELQSALEEAEA 1551


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 1400 bits (3624), Expect = 0.0
 Identities = 762/1917 (39%), Positives = 1187/1917 (61%), Gaps = 26/1917 (1%)

Query: 25   ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
            A    + AK  V++   +  F  A+++   G +V  +  E G    V  D +  MNPPK+
Sbjct: 27   AQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKY 85

Query: 85   SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
             K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+  ++  YRG
Sbjct: 86   DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRG 145

Query: 145  KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204
            KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + 
Sbjct: 146  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205

Query: 205  RKDH----NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
            +K+      + G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+
Sbjct: 206  KKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265

Query: 261  IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPG 319
            IETYLLEKSR   Q K ER++HIFYQ++S     L   LL+     +Y F+S G I +P 
Sbjct: 266  IETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPS 325

Query: 320  QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379
              D++    T  A+ I+GF+ +E +S+ K+  +V+ +GN+ FK+++  +QA      VA 
Sbjct: 326  IDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 385

Query: 380  KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439
            K  +L  +N  +  +A+  PR+KVG +YV K QT +Q   AV ALAKA Y+++F W+V R
Sbjct: 386  KAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTR 445

Query: 440  INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
            IN+ LD TK+    FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 446  INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504

Query: 500  QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-G 558
            ++EGIEW FIDFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD +F  KL ++  G
Sbjct: 505  KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLG 561

Query: 559  SHSKFQKPRQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616
              + FQKP+  K K  A F +IHYAG VDY    WL KN DPLN+ V  L  +S+ + +A
Sbjct: 562  KSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA 621

Query: 617  ELWKDVDRIVGLDQVTGMTETAFGSAY--KTKKGMFRTVGQLYKESLTKLMATLRNTNPN 674
             L+      VG    TG    A G     K K   F+TV  L++E+L KLM  LR+T+P+
Sbjct: 622  LLF------VG---ATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPH 672

Query: 675  FVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPN 734
            FVRCIIPN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L  +
Sbjct: 673  FVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNAS 732

Query: 735  AIPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFF 793
            AIP+G F+D K+A E+++ ++++D   Y+ G +K+FF+AG+L  LEE RD K+  +I   
Sbjct: 733  AIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRT 792

Query: 794  QAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE 853
            QA+CRG+LAR  + K  ++  ++  +Q N  A++ ++HW W +++ K+KPLL+    E+E
Sbjct: 793  QAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKE 852

Query: 854  LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARL 913
            +    EE  K KE+  K E + +E+E K   L++EKN L  Q+QAE +  A+AEE   +L
Sbjct: 853  MANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQL 912

Query: 914  AAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK 973
               K +LE  + ++  R E+EEE N  L  +K+K++    +L++ +D+ E    K++ EK
Sbjct: 913  IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972

Query: 974  VTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQE 1033
               E K+K + EE+  L++  +K  KEKK +++   +    L  EE+K   L K + K E
Sbjct: 973  HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032

Query: 1034 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093
              + DLE  L++E+K R +LE+AKRKL+G+    Q+   +++    +L  +L KKE E+ 
Sbjct: 1033 QQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMS 1092

Query: 1094 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT 1153
            G  ++ +DE        K ++ELQA+I EL+E+ E+E+ASR KAEKQ+ DLS ELE +  
Sbjct: 1093 GLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1152

Query: 1154 ELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE 1213
             LE+    T+AQ E+  KRE E  ++++ LEE T  HEA    +R++HA ++ EL EQ++
Sbjct: 1153 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID 1212

Query: 1214 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR 1273
              +R K  LEK K  ++ +  +LA  ++ + + K   E   + L+ Q+ E+  K  E  R
Sbjct: 1213 NLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQR 1272

Query: 1274 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN 1333
            L  +L  + ++LQ E    S  L+E +    + ++   +   Q+++ +  L+EE + K  
Sbjct: 1273 LINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSA 1332

Query: 1334 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEE 1392
            L+  ++    + + L+EQ EEE+EA+  L++ +    S++A  + K + D +   E LEE
Sbjct: 1333 LAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE 1392

Query: 1393 AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKK 1452
            AKKKL +  +   + +E        LEKTK RLQ E++DL +D++      + L+KKQ+ 
Sbjct: 1393 AKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRN 1452

Query: 1453 FDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRAD 1512
            FD++LAE K        E + ++ E+R   T+   +  A EE+L+  E  +R+NK L+ +
Sbjct: 1453 FDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQE 1512

Query: 1513 MEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAM 1572
            + DL     + GK +HELEK K+ +EQ+  E++  LEE E  L+  E   LR+++ +  +
Sbjct: 1513 ISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQV 1572

Query: 1573 KAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 1632
            K++ +R +  +DE+ ++ KR  I+ V  +++ L+ E + R  A+  KKKME DL ++E Q
Sbjct: 1573 KSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1632

Query: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQL 1692
            +  AN+   E ++  R  QA +KD Q  L++A  S++++  Q    E++   L+AEI +L
Sbjct: 1633 LNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEEL 1692

Query: 1693 QEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNM 1752
            +  L  +ER+R+ AEQE  + ++ +    +  ++L++ K++LE  I+Q++ E+E+     
Sbjct: 1693 RATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEA 1752

Query: 1753 ELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKF 1812
                ++ +K       +  EL  E+  +   +  ++ LE+  K+L+ +L E E       
Sbjct: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1812

Query: 1813 KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM 1872
            K  I  LEA++ +LE ++E E K    A K +R+ E+K+KE+  Q E++R++  + ++ +
Sbjct: 1813 KKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLV 1872

Query: 1873 EKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
            +K  A++K  KRQ EEAEE++    +  R++Q EL++A E  +    +V+ L+ + R
Sbjct: 1873 DKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929



 Score =  241 bits (614), Expect = 7e-63
 Identities = 222/1006 (22%), Positives = 463/1006 (46%), Gaps = 79/1006 (7%)

Query: 955  LEEQLDEEEG---ARQKLQLEKVTAEAKIKKM---EEEILLLEDQNSKFIKEKKLMEDRI 1008
            LEE  DE+      R +       A  + +KM    E I  ++     F+  K     ++
Sbjct: 777  LEEMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKL 836

Query: 1009 AECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQ 1068
                  L +  E  K +A ++ + E      +E L K E  R+ELE+    L  E  DLQ
Sbjct: 837  YFKIKPLLKSAETEKEMANMKEEFE----KTKEELAKTEAKRKELEEKMVTLMQEKNDLQ 892

Query: 1069 -------DQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIA 1121
                   D +A+ + + D+L     + E +++    R +DE           R+L+ + +
Sbjct: 893  LQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS 952

Query: 1122 ELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKK 1181
            EL++D +  + +  K EK+K     +++ L  E+   LD T A+    TK ++ + E  +
Sbjct: 953  ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG-LDETIAKL---TKEKKALQEAHQ 1008

Query: 1182 ALEEETKNHEAQIQDMRQ---RHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELAC 1238
               ++ +  E ++  + +   +    +++L   LEQ K+ + +LE+ K+ LE D K    
Sbjct: 1009 QTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQE 1068

Query: 1239 EVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEE 1298
                ++  K + + K KK + ++  L +K+ +   L ++L +K  +LQ  ++ +   +E 
Sbjct: 1069 STMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEA 1128

Query: 1299 AEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEA 1358
                  K  K  + L  +L++  E L+E        S++I   ++ +   Q+ + + EEA
Sbjct: 1129 ERASRAKAEKQRSDLSRELEEISERLEEAGGAT---SAQIEMNKKREAEFQKMRRDLEEA 1185

Query: 1359 RKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKL 1418
                E     L+ + AD+  ++ +    I++L+  K+KL K+   +   +++ A   + +
Sbjct: 1186 TLQHEATAATLRKKHADSVAELGEQ---IDNLQRVKQKLEKEKSEMKMEIDDLASNMETV 1242

Query: 1419 EKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEA 1478
             K K  L++    L    D   ++ +  E++Q+  + L A+     AR   E      + 
Sbjct: 1243 SKAKGNLEKMCRALE---DQLSEIKTKEEEQQRLINDLTAQR----ARLQTESGEYSRQL 1295

Query: 1479 REKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALE 1538
             EK+T    L+R        K+ F +Q ++L+  +E+ + +K  +    H L+ S+    
Sbjct: 1296 DEKDTLVSQLSRG-------KQAFTQQIEELKRQLEEEIKAKSALA---HALQSSRH--- 1342

Query: 1539 QQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV 1598
               + +R Q EE ++     + A  +    +   + ++E D   R E+ EE K+ L +++
Sbjct: 1343 -DCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401

Query: 1599 RELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQ 1658
            ++ E  +E    + A    +K++++ +++DL   +E  N A   + K+ R     + +++
Sbjct: 1402 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1461

Query: 1659 RELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ-------EELASSERARRHAEQERD 1711
            ++ EE  A   E+ A  KES    +SL  E+ +++       ++L + +R  ++ +QE  
Sbjct: 1462 QKCEETHA---ELEASQKES----RSLSTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1514

Query: 1712 ELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNA 1771
            +L ++I         L   K+++E   ++L+  LEE ++++E    +  +  L+++ + +
Sbjct: 1515 DLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKS 1574

Query: 1772 ELAAERSAAQKSDNARQQ-------LERQNKELKAKLQELEGAVKSKFKATISALEAKIG 1824
            E+  +R  A+K +   Q        +E     L A+++    A++ K K     +E  + 
Sbjct: 1575 EV--DRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK-----MEGDLN 1627

Query: 1825 QLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKR 1884
            ++E QL    +  A A +  R T+  LK+  + ++D  R  +  KEQ+     R   L+ 
Sbjct: 1628 EMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA 1687

Query: 1885 QLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
            ++EE      +   SR+  ++EL DA+E  + L  + ++L N  ++
Sbjct: 1688 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1733



 Score =  196 bits (498), Expect = 2e-49
 Identities = 190/940 (20%), Positives = 411/940 (43%), Gaps = 146/940 (15%)

Query: 839  TKVKPLLQVTRQE--EELQAKDEEL-------LKVKEKQTKVEGELEEMERKHQQLLEEK 889
            TK K  LQ   Q+  ++LQA+++++       +K++++   +EG LE+ ++    L   K
Sbjct: 997  TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1056

Query: 890  NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
              L   L+   E   + E  + +L  K ++ E  +  L+S++E+E+     LQ + K++Q
Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116

Query: 950  AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEE-----------EILLLEDQNSKFI 998
            A I++LEE+++ E  +R K + ++     +++++ E           +I + + + ++F 
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176

Query: 999  KEKKLME------------------DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLE 1040
            K ++ +E                  D +AE   Q+   +   + L K +++ ++ I DL 
Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1236

Query: 1041 ERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGD 1100
              ++   K +  LEK  R L+ + ++++ +  E Q  I++L  Q A+ + E      + D
Sbjct: 1237 SNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLD 1296

Query: 1101 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
            ++    +   +  +    QI EL+   E E  +++      +    + + L+ + E+  +
Sbjct: 1297 EKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQE 1356

Query: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220
              A  Q   +K   EVA+ +   E +      ++++ +++ A  L++  E +E      A
Sbjct: 1357 AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCA 1416

Query: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDA-------QVQELHAKVSEGDR 1273
            +LEK KQ L+ + ++L  +V+      A  + K++  D        + +E HA++    +
Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQK 1476

Query: 1274 LRVELAEKASKLQN----ELDNVSTL------------------------LEEAEKKGIK 1305
                L+ +  K++N     LD + TL                        + E EK   +
Sbjct: 1477 ESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1536

Query: 1306 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN-SLQEQQEEEEEARKNLEK 1364
              ++ + L++ L++ +  L+ E  + L +   + Q++ E +  + E+ EE ++ ++N  +
Sbjct: 1537 VEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIR 1596

Query: 1365 QVLALQSQL-------------------------------------------------AD 1375
             V ++QS L                                                  D
Sbjct: 1597 IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKD 1656

Query: 1376 TKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVD 1435
            T+  +DD L + E L+E    + + A  L   +EE     ++ E+++   +QEL D +  
Sbjct: 1657 TQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER 1716

Query: 1436 LDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEA 1495
            +       ++L   +KK +  +++ +       +E   AE +A++  T A  +A  L++ 
Sbjct: 1717 VQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKE 1776

Query: 1496 LEAKEEFERQNKQLRADMEDLMSSKDDVG--------KNVHELEKSKRALEQQVE-EMRT 1546
             +     ER  K L   ++DL    D+          K + +LE   R LE +VE E + 
Sbjct: 1777 QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKR 1836

Query: 1547 QLEEL-----------EDELQATEDAK--LRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593
             +E +           E   Q  ED K  LRL+  +  ++A+  +  + + E+ EE+  +
Sbjct: 1837 NVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKV-KSYKRQAEEAEEQSNV 1895

Query: 1594 LIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQI 1633
             + + R ++ ELE+  ++  +A +   K+ +  +++  +I
Sbjct: 1896 NLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1935



 Score =  172 bits (437), Expect = 2e-42
 Identities = 152/724 (20%), Positives = 344/724 (47%), Gaps = 33/724 (4%)

Query: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
            A  + + +K   ++ +  AK  E +   V L ++ + LQ ++   +  L +AE++  +  
Sbjct: 854  ANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLI 913

Query: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
            K    LE+++++  E  ++E      L+++ R+LE+E + L++  ++ E     +EK+  
Sbjct: 914  KTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 973

Query: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDK---LEKTKNR 1424
            A ++++ +  +++     TI  L + KK L    EA  Q L++     DK   L K K +
Sbjct: 974  ATENKVKNLTEEMAGLDETIAKLTKEKKAL---QEAHQQTLDDLQAEEDKVNTLTKAKIK 1030

Query: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISARYAEERDRAEAEAREKE 1482
            L+Q++DDL   L+ ++++  +LE+ ++K   D  LA+E ++      ++ + + + ++KE
Sbjct: 1031 LEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIE--NDKQQLDEKLKKKE 1088

Query: 1483 TKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE 1542
             +   L   +E+      + +++ K+L+A +E+L    +    +  + EK +  L +++E
Sbjct: 1089 FEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148

Query: 1543 EMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ----V 1598
            E+  +LEE      A  +   + E   Q M+    RDL+    Q+E     L K+    V
Sbjct: 1149 EISERLEEAGGATSAQIEMNKKREAEFQKMR----RDLEEATLQHEATAATLRKKHADSV 1204

Query: 1599 RELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQ 1658
             EL  ++++ ++ +      K +M++++ DL + +E  +KA+  + K  R L+ Q+ + +
Sbjct: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK 1264

Query: 1659 RELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEIT 1718
             + EE +   +++ AQ    + +      ++ +    ++   R ++   Q+ +EL  ++ 
Sbjct: 1265 TKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLE 1324

Query: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 1778
                 KSAL    +        L E+ EEEQ     L     K   +V     +   E  
Sbjct: 1325 EEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKY--ETD 1382

Query: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1838
            A Q+++    +LE   K+L  +LQ+ E  V++     ++A  A + + +++L+ E ++  
Sbjct: 1383 AIQRTE----ELEEAKKKLAQRLQDAEEHVEA-----VNAKCASLEKTKQRLQNEVEDLM 1433

Query: 1839 AANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANA 1898
                 V RT      +  +  +  +   ++K++ E+ +A ++  +++      E  +   
Sbjct: 1434 ID---VERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKN 1490

Query: 1899 SRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDD 1958
            +  +   +L+     N+ L +E+S L  ++  GG          ++Q+  E + L+ + +
Sbjct: 1491 AYEESLDQLETLKRENKNLQQEISDLTEQIAEGGK-RIHELEKIKKQVEQEKSELQAALE 1549

Query: 1959 DTES 1962
            + E+
Sbjct: 1550 EAEA 1553



 Score = 39.3 bits (90), Expect = 0.039
 Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 19/130 (14%)

Query: 849  RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEE---------KNIL-----AE 894
            +Q ++L+A+  EL    E + K   E  +  RKH++ ++E         KNIL      +
Sbjct: 1814 KQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVD 1873

Query: 895  QLQAETELFA-EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953
            +LQA+ + +  +AEE   +      +   I H+LE    E EER  I +++  K++   +
Sbjct: 1874 KLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELE----EAEERADIAESQVNKLRVKSR 1929

Query: 954  DLEEQLDEEE 963
            ++  ++  EE
Sbjct: 1930 EVHTKIISEE 1939


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 1396 bits (3613), Expect = 0.0
 Identities = 765/1924 (39%), Positives = 1190/1924 (61%), Gaps = 40/1924 (2%)

Query: 25   ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
            A    + AK  V++   +  +  A ++   G +V  +  E G    V +D +  MNPPK+
Sbjct: 27   AQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKY 85

Query: 85   SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
             K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y+  ++  YRG
Sbjct: 86   DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRG 145

Query: 145  KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204
            KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + 
Sbjct: 146  KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205

Query: 205  RKDH----NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
            +K+      + G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+
Sbjct: 206  KKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASAD 265

Query: 261  IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGYIPIPG 319
            IETYLLEKSR   Q K ER++HIFYQ+LS     L   LL+     ++ F+S G I +P 
Sbjct: 266  IETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPS 325

Query: 320  QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379
              D++    T  A+ I+GF+ +E +++ K+  +V+ +GN+ FK+++  +QA      VA 
Sbjct: 326  IDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 385

Query: 380  KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439
            K  +L  +N  +  +++  PR+KVG ++V K QT +Q   AV ALAKA YE++F W+V R
Sbjct: 386  KAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTR 445

Query: 440  INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
            IN+ LD TK+    FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 446  INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504

Query: 500  QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-G 558
            ++EGIEW FIDFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD +F  KL ++  G
Sbjct: 505  KKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLG 561

Query: 559  SHSKFQKPRQLKDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616
              + FQKP+  K K  A F ++HYAG VDY    WL KN DPLN+ V  L  +S+ + +A
Sbjct: 562  KSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA 621

Query: 617  ELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGM-FRTVGQLYKESLTKLMATLRNTNPNF 675
             L+            T   E   G     KKG  F+TV  L++E+L KLM  LR+T+P+F
Sbjct: 622  FLFSGAQ--------TAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHF 673

Query: 676  VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA 735
            VRCIIPN  K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L  +A
Sbjct: 674  VRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASA 733

Query: 736  IPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQ 794
            IP+G F+D K+A E+++ ++E+D   Y+ G +K+FF+AG+L  LEE RD K+  +I   Q
Sbjct: 734  IPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQ 793

Query: 795  AVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEEL 854
            A+CRG+L R  F K  ++  ++  +Q N  A++ ++HW W +++ K+KPLL+    E+E+
Sbjct: 794  AICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEM 853

Query: 855  QAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLA 914
                EE  K KE+  K E + +E+E K   L++EKN L  Q+QAE +  A+AEE   +L 
Sbjct: 854  ANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLI 913

Query: 915  AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV 974
              K +LE  + ++  R E+EEE N  L  +K+K++    +L++ +D+ E    K++ EK 
Sbjct: 914  KTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 973

Query: 975  TAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEV 1034
              E K+K + EE+  L++  +K  KEKK +++   +    L  EE+K   L K + K E 
Sbjct: 974  ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQ 1033

Query: 1035 MISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQG 1094
             + DLE  L++E+K   +LE+AKRKL+G+    Q+   + +    +L  +L KKE E+  
Sbjct: 1034 QVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSN 1093

Query: 1095 ALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTE 1154
               + +DE        K ++ELQA+I EL+E+ E+E+ASR KAEKQ+ DLS ELE +   
Sbjct: 1094 LQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER 1153

Query: 1155 LEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQ 1214
            LE+    T+AQ E+  KRE E  ++++ LEE T  HEA    +R++HA ++ EL EQ++ 
Sbjct: 1154 LEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDS 1213

Query: 1215 AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRL 1274
             +R K  LEK K  L+ +  +LA  ++ + + KA  E   + L+ Q+ E+  K  E  RL
Sbjct: 1214 LQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRL 1273

Query: 1275 RVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNL 1334
              EL+ + ++L  E    S  L+E +    + ++   +   Q+++ +  L+EET+ K  L
Sbjct: 1274 INELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTL 1333

Query: 1335 SSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEA 1393
            +  ++    + + L+EQ EEE+EA+  L++ +    S++A  + K + D +   E LEEA
Sbjct: 1334 AHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEA 1393

Query: 1394 KKKL---LKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ 1450
            KKKL   L+DAE   + +  K  +   LEKTK RLQ E++DL +D++        L+KKQ
Sbjct: 1394 KKKLAQRLQDAEEHVEAVNSKCAS---LEKTKQRLQNEVEDLMIDVERSNAACIALDKKQ 1450

Query: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALS-----LARALEEALEAKEEFERQ 1505
            + FD++LAE K    +Y  E  +AE EA +KE+++LS     +  A EE+L+  E  +R+
Sbjct: 1451 RNFDKVLAEWKQ---KY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRE 1505

Query: 1506 NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRL 1565
            NK L+ ++ DL     + GK++HELEK K+ L+ +  E++T LEE E  L+  E   LR+
Sbjct: 1506 NKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRI 1565

Query: 1566 EVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEID 1625
            ++ +  +K++ +R +  +DE+ ++ KR  ++ V  +++ L+ E + R  A+  KKKME D
Sbjct: 1566 QLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGD 1625

Query: 1626 LKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSL 1685
            L ++E Q+  AN+   E ++ LR  Q  +KD Q  L++A   +D++  Q    E++   +
Sbjct: 1626 LNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLM 1685

Query: 1686 EAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEEL 1745
            +AE+ +L+  L  +ER R+ AEQE  + ++ +    +  ++L++ K++LE  I+Q++ E+
Sbjct: 1686 QAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEM 1745

Query: 1746 EEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE 1805
            E+         ++ +K       +  EL  E+  +   +  ++ +E+  K+L+ +L E E
Sbjct: 1746 EDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAE 1805

Query: 1806 GAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHA 1865
                   K  I  LEA++ +LE ++E E K    A K +R+ E+++KE+  Q E++R++ 
Sbjct: 1806 QLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNI 1865

Query: 1866 DQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLK 1925
             + ++ ++K   ++K  KRQ EEAEE++    A  RKLQ EL++A E  +    +V+ L+
Sbjct: 1866 LRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLR 1925

Query: 1926 NRLR 1929
             + R
Sbjct: 1926 VKSR 1929



 Score =  238 bits (607), Expect = 4e-62
 Identities = 214/979 (21%), Positives = 448/979 (45%), Gaps = 79/979 (8%)

Query: 979  KIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD 1038
            K+ +  E I  ++     F+  K     ++      L +  E  K +A ++ + E     
Sbjct: 807  KMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE----K 862

Query: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQ-------DQIAELQAQIDELKLQLAKKEEE 1091
             +E L K E  R+ELE+    L  E  DLQ       D +A+ + + D+L     + E +
Sbjct: 863  TKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAK 922

Query: 1092 LQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEAL 1151
            ++    R +DE           R+L+ + +EL++D +  + +  K EK+K     +++ L
Sbjct: 923  IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 982

Query: 1152 KTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDM---RQRHATALEEL 1208
              E+   LD T A+    TK ++ + E  +   ++ +  E ++  +   + +    +++L
Sbjct: 983  TEEMAG-LDETIAKL---TKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDL 1038

Query: 1209 SEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKV 1268
               LEQ K+   +LE+ K+ LE D K         +  K +   K KK + ++  L  K+
Sbjct: 1039 EGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKI 1098

Query: 1269 SEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEET 1328
             +   L ++L +K  +LQ  ++ +   +E       K  K  + L  +L++  E L+E  
Sbjct: 1099 EDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1158

Query: 1329 RQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIE 1388
                  S++I   ++ +   Q+ + + EE+    E    AL+ + AD+  ++ +    I+
Sbjct: 1159 GAT---SAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQ---ID 1212

Query: 1389 SLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEK 1448
            SL+  K+KL                     EK K+ L+ E++DL  +++   +  +N EK
Sbjct: 1213 SLQRVKQKL---------------------EKEKSELKMEINDLASNMETVSKAKANFEK 1251

Query: 1449 KQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQ 1508
              +  +  L+E K+         +   A+     T++   +R L+E      +  R  + 
Sbjct: 1252 MCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQA 1311

Query: 1509 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 1568
                +E+L        + + E  K+K  L   ++  R   + L ++ +  ++AK  L+  
Sbjct: 1312 FTQQIEELK-------RQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRG 1364

Query: 1569 MQAMKAQ-------FERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKK 1621
            M    ++       +E D   R E+ EE K+ L +++++ E  +E    + A    +K++
Sbjct: 1365 MSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQR 1424

Query: 1622 MEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKK 1681
            ++ +++DL   +E +N A   + K+ R     + +++++ EE +A   E+ A  KES   
Sbjct: 1425 LQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQA---ELEASQKES--- 1478

Query: 1682 LKSLEAEILQLQ-------EELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL 1734
             +SL  E+ +++       + L + +R  ++ +QE  +L ++I         L   K++L
Sbjct: 1479 -RSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQL 1537

Query: 1735 EARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN 1794
            +   ++L+  LEE ++++E    +  +  L+++ + +E+  +R  A+K D    QL+R +
Sbjct: 1538 DHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEK-DEELDQLKRNH 1594

Query: 1795 KELKAKLQE-LEGAVKSKFKATI--SALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKL 1851
              +   +Q  L+  ++S+  A      +E  + ++E QL    ++ A A + +R T+  L
Sbjct: 1595 LRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGIL 1654

Query: 1852 KEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDAT 1911
            K+  + ++D  R  D  KEQ+     R   ++ ++EE      R    R+  ++EL DA+
Sbjct: 1655 KDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDAS 1714

Query: 1912 EANEGLSREVSTLKNRLRR 1930
            E  + L  + ++L N  ++
Sbjct: 1715 ERVQLLHTQNTSLINTKKK 1733



 Score =  226 bits (575), Expect = 2e-58
 Identities = 211/954 (22%), Positives = 431/954 (45%), Gaps = 108/954 (11%)

Query: 839  TKVKPLLQVTRQE--EELQAKDEELLKVKEKQTKVEGELEEMERKHQQ-------LLEEK 889
            TK K  LQ   Q+  ++LQ +++++  + + +TK+E +++++E   +Q       L   K
Sbjct: 997  TKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAK 1056

Query: 890  NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
              L   L+   E   + E  + +L  K ++ E  + +L+ ++E+E+     LQ + K++Q
Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQ 1116

Query: 950  AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEE-----------EILLLEDQNSKFI 998
            A I++LEE+++ E  +R K + ++     +++++ E           +I + + + ++F 
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176

Query: 999  KEKKLME------------------DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLE 1040
            K ++ +E                  D +AE   Q+   +   + L K +++ ++ I+DL 
Sbjct: 1177 KMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLA 1236

Query: 1041 ERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGD 1100
              ++   K +   EK  R L+ + ++++ +  E Q  I+EL  Q A+   E      + D
Sbjct: 1237 SNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLD 1296

Query: 1101 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
            ++    +   +  +    QI EL+   E E  +++      +    + + L+ + E+  +
Sbjct: 1297 EKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQE 1356

Query: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220
              A  Q   +K   EVA+ +   E +      ++++ +++ A  L++  E +E      A
Sbjct: 1357 AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCA 1416

Query: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
            +LEK KQ L+ + ++L  +V+         + K++  D  + E   K  E  +  +E ++
Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEE-TQAELEASQ 1475

Query: 1281 KASK-LQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIR 1339
            K S+ L  EL  V    EE+        ++  +L+ ++ D  E + E  +    L    +
Sbjct: 1476 KESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKK 1535

Query: 1340 QLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTI-ESLEEAKKKLL 1398
            QL+ EK+ LQ   EE E + ++ E ++L +Q +L   K ++D  +    E L++ K+  L
Sbjct: 1536 QLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHL 1595

Query: 1399 KDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASN-----------LE 1447
            +  E++   L+ +  + +   + K +++ +L+++ + L+H  + A+            L+
Sbjct: 1596 RVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILK 1655

Query: 1448 KKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLAR-------ALEEALEAKE 1500
              Q   D  +  +  +  + A    RA     E E    SL R       A +E L+A E
Sbjct: 1656 DTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASE 1715

Query: 1501 EFE---RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
              +    QN  L    + L +    +   + ++ +  R  E++ ++  T    + +EL+ 
Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKK 1775

Query: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE------KKRL--LIKQVRELEAELEDER 1609
             +D    LE  M+    Q  +DLQ R ++ E+      KK++  L  +VRELE+E+E E+
Sbjct: 1776 EQDTSAHLE-RMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQ 1834

Query: 1610 KQRALAVASKKKMEIDLKDL----------------------------EAQIEAANKARD 1641
            K    AV   +K E  +K+L                            + Q E A +  +
Sbjct: 1835 KHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSN 1894

Query: 1642 EVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEE 1695
              + + RKLQ        ELEEA+   D   A+S+ ++ ++KS E     + EE
Sbjct: 1895 VNLAKFRKLQ-------HELEEAKERAD--IAESQVNKLRVKSREVHTKVISEE 1939



 Score =  173 bits (439), Expect = 1e-42
 Identities = 164/737 (22%), Positives = 339/737 (45%), Gaps = 59/737 (8%)

Query: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
            A  + + +K   ++ +  AK  E +   V L ++ + LQ ++   +  L +AE++  +  
Sbjct: 854  ANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLI 913

Query: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
            K    LE+++++  E  ++E      L+++ R+LE+E + L++  ++ E     +EK+  
Sbjct: 914  KTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKH 973

Query: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDK---LEKTKNR 1424
            A ++++ +  +++     TI  L + KK L    EA  Q L++  +  DK   L K K +
Sbjct: 974  ATENKVKNLTEEMAGLDETIAKLTKEKKAL---QEAHQQTLDDLQMEEDKVNTLTKAKTK 1030

Query: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKF--DQLLAEEKSISARYAEERDRAEAEAREKE 1482
            L+Q++DDL   L+ ++++  +LE+ ++K   D  LA+E ++      ++ +   + ++KE
Sbjct: 1031 LEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTE--NDKQQLNEKLKKKE 1088

Query: 1483 TKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE 1542
             +  +L   +E+      + +++ K+L+A +E+L    +    +  + EK +  L +++E
Sbjct: 1089 FEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148

Query: 1543 EMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ----V 1598
            E+  +LEE      A  +   + E   Q M+    RDL+    Q+E     L K+    V
Sbjct: 1149 EISERLEEAGGATSAQIEMNKKREAEFQKMR----RDLEESTLQHEATAAALRKKHADSV 1204

Query: 1599 RELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM---- 1654
             EL  +++  ++ +      K ++++++ DL + +E  +KA+    K  R L+ Q+    
Sbjct: 1205 AELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIK 1264

Query: 1655 ---KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERD 1711
               ++ QR + E  A +  +  +S E  ++L   +A + QL        R ++   Q+ +
Sbjct: 1265 TKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLS-------RGKQAFTQQIE 1317

Query: 1712 ELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNA 1771
            EL  ++      KS L    +        L E+ EEEQ     L     K   +V     
Sbjct: 1318 ELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRT 1377

Query: 1772 ELAAERSAAQKSDNARQQLERQNKELKAKLQELEG---AVKSK---FKATISALEAKIGQ 1825
            +   E  A Q+++    +LE   K+L  +LQ+ E    AV SK    + T   L+ ++  
Sbjct: 1378 KY--ETDAIQRTE----ELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVED 1431

Query: 1826 LEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQ 1885
            L   +E+      A +K  R  +K L E              +K++ E+  A ++  +++
Sbjct: 1432 LMIDVERSNAACIALDKKQRNFDKVLAE--------------WKQKYEETQAELEASQKE 1477

Query: 1886 LEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQ 1945
                  E  +   +  +    L+     N+ L +E+S L  ++  GG          ++Q
Sbjct: 1478 SRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGK-HIHELEKVKKQ 1536

Query: 1946 LHLEGASLELSDDDTES 1962
            L  E + L+ S ++ E+
Sbjct: 1537 LDHEKSELQTSLEEAEA 1553



 Score =  119 bits (298), Expect = 3e-26
 Identities = 111/489 (22%), Positives = 225/489 (46%), Gaps = 19/489 (3%)

Query: 1486 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR 1545
            L  A   +E    KEEFE+  ++L A  E   + + ++ + +  L + K  L+ QV+   
Sbjct: 844  LKSAETEKEMANMKEEFEKTKEEL-AKTE---AKRKELEEKMVTLMQEKNDLQLQVQAEA 899

Query: 1546 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL 1605
              L + E+        K++LE  ++ +  + E + +   E    KKR L  +  EL+ ++
Sbjct: 900  DALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTA-KKRKLEDECSELKKDI 958

Query: 1606 EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665
            +D     A     K   E  +K+L  ++   ++   ++ K+ + LQ   + +Q+ L++ +
Sbjct: 959  DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQ---EAHQQTLDDLQ 1015

Query: 1666 ASRDEIFAQSKES---EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSAS 1722
               D++   +K     E+++  LE  + Q ++     ERA+R  E +  +LA E T    
Sbjct: 1016 MEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDL-KLAQESTMDTE 1074

Query: 1723 GKSALLDEK-RRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ 1781
                 L+EK ++ E  ++ L+ ++E+EQ+    L  + ++   +++ L  E+ AER++  
Sbjct: 1075 NDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRA 1134

Query: 1782 KSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA-KERAAA 1840
            K++  R  L R+ +E+  +L+E  GA  ++ +      EA+  ++   LE+   +  A A
Sbjct: 1135 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMN-KKREAEFQKMRRDLEESTLQHEATA 1193

Query: 1841 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 1900
              L ++    + E+  Q++  +R     K+++EK  + +K     L    E  ++A A+ 
Sbjct: 1194 AALRKKHADSVAELGEQIDSLQR----VKQKLEKEKSELKMEINDLASNMETVSKAKANF 1249

Query: 1901 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDT 1960
             K+ R L+D     +    E   L N L        + S    RQL  + A +       
Sbjct: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGK 1309

Query: 1961 ESKTSDVNE 1969
            ++ T  + E
Sbjct: 1310 QAFTQQIEE 1318



 Score = 75.9 bits (185), Expect = 4e-13
 Identities = 77/346 (22%), Positives = 157/346 (45%), Gaps = 15/346 (4%)

Query: 809  KQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ 868
            K+  L  ++ +Q    A ++ R+    R+  K++    +   E +L   + +  +     
Sbjct: 1591 KRNHLRVVESMQSTLDAEIRSRN-DALRIKKKMEG--DLNEMEIQLNHANRQAAEALRNL 1647

Query: 869  TKVEGELEEMERKHQQLLEEKNILAEQL----QAETELFAEAEEMRARLAAK---KQELE 921
               +G L++ +      +  ++ L EQL    +    + AE EE+RA L      ++  E
Sbjct: 1648 RNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAE 1707

Query: 922  EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE--EEGARQKLQLEKVTAEAK 979
            + L D   RV+    +N  L N KKK++  I  ++ ++++  +E    + + +K   +A 
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAA 1767

Query: 980  IKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA-KNLAKIRNKQEVMISD 1038
            +  M EE+   +D ++   + KK ME  + +   +L E E+ A K   K   K E  + +
Sbjct: 1768 M--MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRE 1825

Query: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
            LE  ++ E+K   E  K  RK +    +L  Q  E +  I  L+  + K + +++    +
Sbjct: 1826 LESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQ 1885

Query: 1099 GDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDL 1144
             ++     N  L   R+LQ ++ E +E  +  ++  NK   + R++
Sbjct: 1886 AEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREV 1931


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 1383 bits (3579), Expect = 0.0
 Identities = 778/1916 (40%), Positives = 1162/1916 (60%), Gaps = 28/1916 (1%)

Query: 30   WTAKKLVWIPSERHGFEAASIKEER-GDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVE 88
            W  KK VW+P E+  +  A +K E  G  V VE  +  K  MV + ++Q MNPP+F  +E
Sbjct: 71   WDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQ-KVLMVREAELQPMNPPRFDLLE 129

Query: 89   DMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRH 148
            DMA +T LNEASVLHNL+ RY   +IYTYSGLFCV INPYK LP+Y+ +++  Y+GK+R 
Sbjct: 130  DMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRS 189

Query: 149  EMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS--SHKGRK 206
            + PPHIYA++++AY  ML++R++QS+L TGESGAGKT NTK+VIQY A VA+     G+K
Sbjct: 190  DSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKK 249

Query: 207  DHNIP----GELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262
               +     G LE Q+++ANP +E+FGNAKT++NDNSSRFGKFIRI+F  +G +  A+I+
Sbjct: 250  AQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADID 309

Query: 263  TYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN--NYRFLSNGYIPIPGQ 320
            +YLLEKSR + Q   ER++H++YQ+LSG    L+ D+LL   N  +Y F S G I +   
Sbjct: 310  SYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQ-DMLLLSMNPYDYHFCSQGVITVDNM 368

Query: 321  QDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQK 380
             D +    T  AM I+GFS +E  +  K+V ++L FGN+ FK+++  +QA       A K
Sbjct: 369  NDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADK 428

Query: 381  LCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRI 440
              +L+G++  +  + +L PR++VG +YV K Q+ EQ  FAV ALAKATY+RLFRWLV RI
Sbjct: 429  AAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRI 488

Query: 441  NKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQ 500
            N+ LD TK     FIG+LDIAGFEIFE NSFEQLCIN+TNEKLQQ FN  MF+LEQEEY+
Sbjct: 489  NQTLD-TKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYK 547

Query: 501  REGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GS 559
            REGI+W FIDFGLDLQPCIDLIE+P    G+L++L+EEC FPKA+D +F  KL     G 
Sbjct: 548  REGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDNHAGK 604

Query: 560  HSKFQKPR---QLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616
               FQ+PR   + K +A F ++HYAG V Y    WL KN DPLN+ V  +  +S +R +A
Sbjct: 605  SPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLA 664

Query: 617  ELWKDVDRIVGLDQV-TGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNF 675
             L+++       +   +G+ E       + K   F+TV QL+KE+L KLM  LR T P+F
Sbjct: 665  TLYENYAGSCSTEPPKSGVKEK------RKKAASFQTVSQLHKENLNKLMTNLRATQPHF 718

Query: 676  VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA 735
            VRCI+PN  K  G +D  LVL QLRCNGVLEGIRICRQGFPNR+++ +FRQRY IL P+A
Sbjct: 719  VRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSA 778

Query: 736  IPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQ 794
            IP   FMD ++A E+++ +L+LD   Y+ G +K+FF+AG+L  LEE RD ++  ++   Q
Sbjct: 779  IPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQ 838

Query: 795  AVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEEL 854
            A  RG L R  + +      AL  +Q N  A+  +++W W ++F K+KPLL+  + EEEL
Sbjct: 839  ARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEEL 898

Query: 855  QAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLA 914
             A   EL  ++      E + +E+E  H  + +EKN LA QLQAE +  A+AEE    L 
Sbjct: 899  AALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLI 958

Query: 915  AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV 974
              K +LE  + +L  R+E+EEE N  L   ++K++    +L++ +D+ +    K + EK 
Sbjct: 959  KSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQ 1018

Query: 975  TAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEV 1034
              E K+K + EE+  L++  ++  KEKK +++   +    L  EE++   L K + + E 
Sbjct: 1019 ATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQ 1078

Query: 1035 MISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQG 1094
             + DLE  L++E+K R + E+AKRKL+G+    Q+ +A+      +L+ +L KK+ EL  
Sbjct: 1079 QVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQ 1138

Query: 1095 ALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTE 1154
               R +DE L      K ++ELQA+  EL+E+ E+E+A+R + EKQ+ + + ELE L   
Sbjct: 1139 LSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSER 1198

Query: 1155 LEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQ 1214
            LE+    +A Q+E   KRE E+  L++ LEE    HEA +  +R++ A    EL EQ++ 
Sbjct: 1199 LEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDS 1258

Query: 1215 AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRL 1274
             +R +  LEK K  L  +  +LA  V+ L + KA +E   +  + Q+ E   KV E  R 
Sbjct: 1259 LQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQ 1318

Query: 1275 RVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNL 1334
              + + +  +LQ E   +S LLEE E    + ++  A     L++ +  L+EE++ K  L
Sbjct: 1319 LADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSAL 1378

Query: 1335 SSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVD-DDLGTIESLEEA 1393
            +  ++ L  + + L+EQ EEE EA+  L++ +    +++A  + K + D +   E LEEA
Sbjct: 1379 AHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEA 1438

Query: 1394 KKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF 1453
            KKKL    +   + +E        LEK K RLQ E +D+T++L+     A+ L+KKQ+  
Sbjct: 1439 KKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHL 1498

Query: 1454 DQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADM 1513
            ++ L E +        E + A+ E+R   T+   L    EEALEA E  +R+NK L+ ++
Sbjct: 1499 ERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEI 1558

Query: 1514 EDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK 1573
             DL       GK++ ELEK+K+ALE +  E++  LEE E  L+  E   LR+++ +  +K
Sbjct: 1559 SDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 1618

Query: 1574 AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQI 1633
            A+ +R L  +DE+    +R   + V  L+A L+ E + R  A+  KKKME DL DLE Q+
Sbjct: 1619 AEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQL 1678

Query: 1634 EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ 1693
              A +   E     R +QAQ+K+ Q   +E +    E+  Q++  E++   L AE+ +L+
Sbjct: 1679 GHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELR 1738

Query: 1694 EELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNME 1753
              L   ER+RR AEQE  E  + +    S  + LL++K++LEA +AQL  E+EE      
Sbjct: 1739 AALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERR 1798

Query: 1754 LLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFK 1813
               ++ +K       +  EL  E+  +   +  ++ LE+  +EL+A+L+E E A     K
Sbjct: 1799 EAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGK 1858

Query: 1814 ATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQME 1873
              +  LEAK+ +LE +L+ E K+ A A K VR+ E+++KE+  Q E++R++  + ++ ++
Sbjct: 1859 KQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVD 1918

Query: 1874 KANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
            K  +++K  KRQ EEAE++A    A  RK Q ELDDA E  +    + + L+ R R
Sbjct: 1919 KLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTR 1974



 Score =  236 bits (601), Expect = 2e-61
 Identities = 203/906 (22%), Positives = 420/906 (46%), Gaps = 37/906 (4%)

Query: 1040 EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARG 1099
            EE L       + L  A    + +  +L++    +  + ++L LQL  +++ L  A    
Sbjct: 895  EEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADA---- 950

Query: 1100 DDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159
             +E  H     KV  +L+ ++ EL E  E E+        ++R L +E   LK +++D  
Sbjct: 951  -EERCHLLIKSKV--QLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLK 1007

Query: 1160 DTTAAQQELRTKREQEVAELKK---ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK 1216
             T A  ++ +   E +V  L +   AL+E       + + +++ H  AL +L  + ++  
Sbjct: 1008 LTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVS 1067

Query: 1217 RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
                 L K K  LE   ++L C ++  ++++ ++E  ++KL+  ++     V++  + + 
Sbjct: 1068 A----LTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQ 1123

Query: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
            +L EK  K  +EL  +S  +E+ +  G +  K    L+++ ++ +E L+ E   +  +  
Sbjct: 1124 QLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEK 1183

Query: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEA-KK 1395
            +  +   E   L E+ EE   A     +     +++L   ++++++     E+   A ++
Sbjct: 1184 QRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRR 1243

Query: 1396 KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQ 1455
            K  + A  L ++++       KLEK K+ L+ E+DDL  +++   +  ++ EK  + ++ 
Sbjct: 1244 KQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYED 1303

Query: 1456 LLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED 1515
             L+E K        +   A  +    +T++  L+R LEE      +  R        +E+
Sbjct: 1304 QLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE 1363

Query: 1516 LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL-RLEVNMQAMKA 1574
            L    ++  K    L  + +AL    + +R Q EE E E QA     L +    +   ++
Sbjct: 1364 LRRQLEEESKAKSALAHAVQALRHDCDLLREQHEE-EAEAQAELQRLLSKANAEVAQWRS 1422

Query: 1575 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
            ++E D   R E+ EE K+ L  +++E E  +E    + +    +K +++ + +D+  ++E
Sbjct: 1423 KYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELE 1482

Query: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ- 1693
             A  A   + K+ R L+       R LEE R   +E+  + + ++++ + L  E+ +L+ 
Sbjct: 1483 RATSAAAALDKKQRHLE-------RALEERRRQEEEMQRELEAAQRESRGLGTELFRLRH 1535

Query: 1694 ------EELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEE 1747
                  E L + +R  ++ ++E  +L D+++ S      L   K+ LE   ++++  LEE
Sbjct: 1536 GHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEE 1595

Query: 1748 EQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSD---NARQQLERQNKELKAKLQEL 1804
             +  +EL   +  +  L++  + AE+  +R  A+K +   N R+  +R  + L+A L + 
Sbjct: 1596 AEGALELEETKTLRIQLELSQVKAEV--DRKLAEKDEECANLRRNHQRAVESLQASL-DA 1652

Query: 1805 EGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRH 1864
            E   +++       +E  +  LE QL    ++   A    R  + +LKE     ++E+R 
Sbjct: 1653 ETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRL 1712

Query: 1865 ADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTL 1924
            A +  EQ +    R   L  +LEE      +   SRR  ++EL +ATE    L  + + L
Sbjct: 1713 AAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGL 1772

Query: 1925 KNRLRR 1930
             N+ ++
Sbjct: 1773 LNQKKK 1778



 Score =  230 bits (587), Expect = 9e-60
 Identities = 223/945 (23%), Positives = 436/945 (46%), Gaps = 115/945 (12%)

Query: 839  TKVKPLLQVTRQEE--ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQL 896
            TK K  LQ   Q+   +LQA+++ +  + + + ++E ++E++E   +Q   EK +  +  
Sbjct: 1042 TKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQ---EKKLRMDTE 1098

Query: 897  QAETELFAE---AEEMRARLAAKKQELEEILHDLES-------RVEEEEERNQILQNEKK 946
            +A+ +L  +    +E  A  A  KQ+LEE L   +S       RVE+E+     +Q + K
Sbjct: 1099 RAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIK 1158

Query: 947  KMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMED 1006
            ++QA  ++LEE+L+ E  AR +++ ++  A  +++++ E    LE+       +++    
Sbjct: 1159 ELQARAEELEEELEAERAARARVEKQRAEAARELEELSER---LEEAGGASAGQREGCRK 1215

Query: 1007 RIAECSSQLAEEEEKA----KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDG 1062
            R AE      E EE A      +A +R KQ    ++L E++   ++ RQ+LEK K +L  
Sbjct: 1216 REAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRM 1275

Query: 1063 ETTDL---------------------QDQIAELQAQIDELKLQLAKKEEEL------QGA 1095
            E  DL                     +DQ++E + +++EL+ QLA    +        G 
Sbjct: 1276 EVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGE 1335

Query: 1096 LARGDDETLHKNNALKVVRELQAQ-IAELQEDFESEKASRNKAEKQKRDLSEELEALKTE 1154
            L+R  +E     + L   + L AQ + EL+   E E  +++      + L  + + L+ +
Sbjct: 1336 LSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQ 1395

Query: 1155 LEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQ 1214
             E+  +  A  Q L +K   EVA+ +   E +      ++++ +++ A  L+E  E +E 
Sbjct: 1396 HEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEA 1455

Query: 1215 AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRL 1274
            A    ++LEK K  L+T+++++  E++      A  + K++ L+  ++E   +  E  R 
Sbjct: 1456 ANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQR- 1514

Query: 1275 RVELAEKASK-LQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN 1333
             +E A++ S+ L  EL  +    EEA +      ++  +L+ ++ D  + +    +    
Sbjct: 1515 ELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQE 1574

Query: 1334 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTI-ESLEE 1392
            L    + LE EK+ +Q   EE E A +  E + L +Q +L+  K +VD  L    E    
Sbjct: 1575 LEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECAN 1634

Query: 1393 AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKK 1452
             ++   +  E+L   L+ +  A ++  + K +++ +L+DL + L H  + A+  +   + 
Sbjct: 1635 LRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRL 1694

Query: 1453 FDQLLAEEKSISARYAEERDRAEA--EAREKETKALSLARALEEALEAKEEFER------ 1504
                L EE++   R  E+R  AE   +A+  E +A  LA  LEE   A E+ ER      
Sbjct: 1695 MQAQLKEEQA--GRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAE 1752

Query: 1505 ----------------------QNKQLRADMEDLMSSKDDVGKNVHE------------- 1529
                                  Q K+L AD+  L    ++  +   E             
Sbjct: 1753 QELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAA 1812

Query: 1530 ---------------LEKSKRALEQQVEEMRTQLEELEDE-LQATEDAKLRLEVNMQAMK 1573
                           LE+ K+ LEQ V E++ +LEE E   L+  +    +LE  ++ ++
Sbjct: 1813 MMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELE 1872

Query: 1574 AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQI 1633
            A+ + + Q +  +  +  R   ++V+EL  + E++RK  A       K++  +K  + Q 
Sbjct: 1873 AELDAE-QKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQF 1931

Query: 1634 EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
            E A +  +  + + RK Q ++ D +   + A    +++ A+++++
Sbjct: 1932 EEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTRDA 1976



 Score =  142 bits (359), Expect = 2e-33
 Identities = 163/681 (23%), Positives = 297/681 (43%), Gaps = 95/681 (13%)

Query: 1299 AEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEA 1358
            AE +G++ A  AA  E++ Q+ +E     T++K +L+    QL+ E+++L +     EE 
Sbjct: 903  AELRGLRGALAAA--EAKRQELEETHVSITQEKNDLAL---QLQAEQDNLADA----EER 953

Query: 1359 RKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKL 1418
               L K  + L+ ++ +  ++++D+      L   ++KL  +   L + +++  L   K 
Sbjct: 954  CHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKA 1013

Query: 1419 EKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEA 1478
            EK K   + ++ +LT ++    +  + L K++K   +            A ++   + +A
Sbjct: 1014 EKEKQATENKVKNLTEEMAALDESVARLTKEKKALQE------------AHQQALGDLQA 1061

Query: 1479 REKETKALSLARA-LEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRAL 1537
             E    AL+ A+  LE+ +E  E    Q K+LR D E          +   +LE   +  
Sbjct: 1062 EEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTE----------RAKRKLEGDLKLT 1111

Query: 1538 EQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ 1597
            ++ V +     ++LE++L+  +    +L + ++        D Q    Q ++K + L  +
Sbjct: 1112 QESVADAAQDKQQLEEKLKKKDSELSQLSLRVE--------DEQLLGAQMQKKIKELQAR 1163

Query: 1598 VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDY 1657
              ELE ELE ER  RA     + +   +L++L  ++E A  A     +  RK +A++   
Sbjct: 1164 AEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRL 1223

Query: 1658 QRELEEARASRDEIFAQSKESEKKLKSLEAE-ILQLQEELASSERARRHAEQERDELADE 1716
            +RELEEA    +   A        L+  +AE   +L E++ S +R R+  E+E+ EL  E
Sbjct: 1224 RRELEEAALRHEATVAA-------LRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRME 1276

Query: 1717 ITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAE 1776
            + + A+    L   K   E      E++L E +  +E L  +    + Q   L  E    
Sbjct: 1277 VDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGEL 1336

Query: 1777 RSAAQKSDNARQQLERQN-------KELKAKLQELEGAVKSKFKATISALEAKIGQLEEQ 1829
                ++ +    QL R         +EL+ +L+E E   KS     + AL      L EQ
Sbjct: 1337 SRLLEEKECLISQLSRGKALAAQSLEELRRQLEE-ESKAKSALAHAVQALRHDCDLLREQ 1395

Query: 1830 LEQEAKERAAANKL-------------------VRRTE------KKLKEIFMQVEDERRH 1864
             E+EA+ +A   +L                   ++RTE      KKL     + E+    
Sbjct: 1396 HEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEA 1455

Query: 1865 ADQYKEQMEKANARMK--------QLKRQ------LEEAEEEATRANASRRKLQRELDDA 1910
            A+     +EKA  R++        +L+R       L++ +    RA   RR+ + E+   
Sbjct: 1456 ANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRE 1515

Query: 1911 TEANEGLSREVSTLKNRLRRG 1931
             EA +  SR + T   RLR G
Sbjct: 1516 LEAAQRESRGLGTELFRLRHG 1536


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 1375 bits (3559), Expect = 0.0
 Identities = 760/1920 (39%), Positives = 1166/1920 (60%), Gaps = 26/1920 (1%)

Query: 25   ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
            A    + +KK  ++   +  +    I+    D+V+V+  ++ +   +N D +  MNPPKF
Sbjct: 27   AQNRPFDSKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKF 85

Query: 85   SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
             K+EDMA +T L+E +VL+NLK+RY + +IYTYSGLFCV +NPYK LP+Y   ++  YRG
Sbjct: 86   DKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRG 145

Query: 145  KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKG 204
            KKR E PPHI++IS++AY+ ML DR++QSIL TGESGAGKT NTK+VIQY A +A +   
Sbjct: 146  KKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDK 205

Query: 205  RKDHN---IPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261
            +K+     + G LE Q++QANP+LE+FGNAKTV+NDNSSRFGKFIRI+F  TG +  A+I
Sbjct: 206  KKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADI 265

Query: 262  ETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN--NYRFLSNGYIPIPG 319
            ETYLLEKSR   Q   ER++HIFYQ++S     L  DLLL   N  ++ F+S G + +  
Sbjct: 266  ETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVAS 324

Query: 320  QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379
              D +    T  A+ I+GFS EE + + K+  +V+ +GN+ FK+++  +QA      VA 
Sbjct: 325  IDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 384

Query: 380  KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439
            K  +L+G+N  E  + +  PR+KVG +YV K Q  +Q   +V ALAKA YE++F W+V R
Sbjct: 385  KAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTR 444

Query: 440  INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
            IN+ LD TK+    FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 445  INQQLD-TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 503

Query: 500  QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQG 558
            ++EGIEW FIDFG+DL  CI+LIE+P    G+ ++L+EEC FPKATD +F  KL  Q  G
Sbjct: 504  KKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLG 560

Query: 559  SHSKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVA 616
              + FQKP+  K KA+  F ++HYAG VDY    WL KN DPLN+ V  L  +SS + ++
Sbjct: 561  KSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLS 620

Query: 617  ELWKDVDRIVGLDQVTGMTETAFGSAY--KTKKGMFRTVGQLYKESLTKLMATLRNTNPN 674
             L+ +             T  + GS    K K   F+TV  +++E+L KLM  LR+T+P+
Sbjct: 621  FLFSNY--------AGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPH 672

Query: 675  FVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPN 734
            FVRC+IPN  K  G +D +LV+ QLRCNGVLEGIRICR+GFP+RI++ +F+QRY IL  +
Sbjct: 673  FVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNAS 732

Query: 735  AIPKG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFF 793
            AIP+G F+D K A E+++ ++++D   +R G +K+FF+AG+L  LEE RD K+  ++   
Sbjct: 733  AIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTST 792

Query: 794  QAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE 853
            QAVCRGYL R  F K  ++  ++  +Q N  +++ ++HW W  +F K+KPLL+    E+E
Sbjct: 793  QAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKE 852

Query: 854  LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARL 913
            +    E+  + KE+  + E   +E+E K   LL+EKN L  Q+Q+ETE   +AEE    L
Sbjct: 853  MATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGL 912

Query: 914  AAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK 973
               K  LE  + +L  R+EEEEE N  L  +K+ ++     L+  +D+ E    K++ EK
Sbjct: 913  IKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEK 972

Query: 974  VTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQE 1033
               E K+K + EE+  LE+  SK  KEKK +++   +    L  EE+K   L KI  K E
Sbjct: 973  HATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLE 1032

Query: 1034 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093
                DLE  L++E+K R +LE+AKRKL+G+    Q+ I +L+    +++ +L KKE EL 
Sbjct: 1033 QQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELS 1092

Query: 1094 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT 1153
               A+ DDE +H     K ++ELQA+I EL+E+ E+E   R K EKQ+ DL+ ELE +  
Sbjct: 1093 QLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISE 1152

Query: 1154 ELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE 1213
             LE+    T+AQ E+  KRE E  ++++ LEE T  HEA    +R++ A ++ EL EQ++
Sbjct: 1153 RLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQID 1212

Query: 1214 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR 1273
              +R K  LEK K  L+ +  ++A  ++ L + K+  E   + ++ Q  E+ AK  +  +
Sbjct: 1213 NLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQ 1272

Query: 1274 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN 1333
            L  +L  + ++LQ +   +S  +EE E    +  K   +L  QL++ +  ++EET+ K  
Sbjct: 1273 LIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNA 1332

Query: 1334 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEE 1392
            ++  ++    + + L+EQ EEE+EA+  L++ +    S++A  + K + D +   E LEE
Sbjct: 1333 MAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEE 1392

Query: 1393 AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKK 1452
            AKKKL +  +   +  E        LEKTK RLQ E++DL  DL+      + L+KKQ+ 
Sbjct: 1393 AKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRN 1452

Query: 1453 FDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRAD 1512
            FD++LAE K        E + A+ E+R   T+   +  A EE ++  E   R+NK L+ +
Sbjct: 1453 FDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEE 1512

Query: 1513 MEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAM 1572
            + DL     + GKN+ E EK+K+ +EQ+  +++  LEE+E  L+  E   LR+++ +  +
Sbjct: 1513 ISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQV 1572

Query: 1573 KAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 1632
            K++ +R +  +DE+ E+ KR   +    L++ L+ E + R  A+  KKKME DL ++E Q
Sbjct: 1573 KSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQ 1632

Query: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQL 1692
            +  +N+   E  K LR +Q Q+KD Q  L++A  S +++  Q    E++   L  E+ ++
Sbjct: 1633 LGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEM 1692

Query: 1693 QEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNM 1752
            +  L  +ER RR +EQE  + +D +    S  ++L++ K++LEA IAQ + E+E      
Sbjct: 1693 KVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQES 1752

Query: 1753 ELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKF 1812
                ++ +K       +  EL  E+  +   +  ++ LE+  K+L+ +L E E       
Sbjct: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1812

Query: 1813 KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM 1872
            K  I  LE ++ +LE +L+ E K  A A K   + E+K+KE+  Q E++ ++  + ++ +
Sbjct: 1813 KKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLV 1872

Query: 1873 EKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGG 1932
            +K  A++K  KRQ EEAEE+A    +  R++Q EL++A E  +    +V+ L+ + R  G
Sbjct: 1873 DKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVG 1932



 Score =  202 bits (515), Expect = 2e-51
 Identities = 208/941 (22%), Positives = 407/941 (43%), Gaps = 150/941 (15%)

Query: 839  TKVKPLLQVTRQE--EELQAKDEEL-------LKVKEKQTKVEGELEEMERKHQQLLEEK 889
            TK K  LQ   Q+  ++LQ +++++        K++++   +EG LE+ ++    L   K
Sbjct: 997  TKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAK 1056

Query: 890  NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
              L   L+   E   + E  + ++  K ++ E  L  L++++++E+  +   Q + K++Q
Sbjct: 1057 RKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQ 1116

Query: 950  AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIA 1009
            A I++LEE+++ E   R K++ ++     +++++ E +       S  I+  K  E    
Sbjct: 1117 ARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQ 1176

Query: 1010 ECSSQLAEEE-EKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQ 1068
            +    L E   +     A +R KQ   +++L E++   ++ +Q+LEK K +L  E  D+ 
Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMA 1236

Query: 1069 DQIAELQAQIDELKLQLAKKEEELQGALARGDDET--LHKNNALKVVRELQAQIAELQED 1126
              I  L      ++      E++     A+ + +T  +H  N  K    LQ Q  EL   
Sbjct: 1237 SNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKA--RLQTQNGELSHR 1294

Query: 1127 FESEKASRNKAEKQKRDLSEELEALKTELEDTL--------------------------- 1159
             E +++  ++  K K+ L+++LE LK ++E+                             
Sbjct: 1295 VEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEE 1354

Query: 1160 -DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1218
             +  A  Q   +K   EVA+ +   E +      ++++ +++ A  L+E  E  E A   
Sbjct: 1355 QEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSK 1414

Query: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRK-----------KLDAQVQELHAK 1267
             A+LEK KQ L+ + ++L  +++      A  + K++           KLD    EL A 
Sbjct: 1415 CASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAA 1474

Query: 1268 VSEGDRLRVELAEKASKLQNELDNVSTL------------------------LEEAEKKG 1303
              E   L  EL +  +  +  +D + TL                        L+EAEK  
Sbjct: 1475 QKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTK 1534

Query: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN-SLQEQQEEEEEARKNL 1362
                ++ + L+  L++ +  L+ E  + L +   + Q++ E +  + E+ EE E+ ++N 
Sbjct: 1535 KLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNS 1594

Query: 1363 EKQVLALQSQL----------ADTKKKVDDDLGTIE--------SLEEAKKKL------L 1398
            ++   ALQS L             KKK++ DL  +E         + E +K L      L
Sbjct: 1595 QRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL 1654

Query: 1399 KDAEA-------------------------LSQRLEEKALAYDKLEKTKNRLQQELDDLT 1433
            KD++                          L + LEE  +A ++ E+T+   +QEL D +
Sbjct: 1655 KDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714

Query: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493
              +       ++L   +KK +  +A+ ++      +E   AE +A++  T A  +A  L+
Sbjct: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELK 1774

Query: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVG--------KNVHELEKSKRALEQQVE-EM 1544
            +  +     ER  K L   ++DL    D+          K + +LE   R LE +++ E 
Sbjct: 1775 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQ 1834

Query: 1545 RTQLEEL-----------EDELQATEDAK--LRLEVNMQAMKAQFERDLQTRDEQNEEKK 1591
            +   E L           E   QA ED K  LRL+  +  ++A+  +  + + E+ EE+ 
Sbjct: 1835 KRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKV-KSYKRQAEEAEEQA 1893

Query: 1592 RLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 1632
               + + R ++ ELE+  ++  +A +   K+    +D+ +Q
Sbjct: 1894 NTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQ 1934



 Score =  158 bits (400), Expect = 4e-38
 Identities = 161/735 (21%), Positives = 328/735 (44%), Gaps = 69/735 (9%)

Query: 840  KVKPLLQVTRQEEELQAKD-----EELLKVKEKQTK----VEGELEEMERKHQQ---LLE 887
            +VK  L+  + E +++  D     E L K K    +    VE +  E++ K +Q   L+ 
Sbjct: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIH 1275

Query: 888  EKNILAEQLQAE----TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQN 943
            + N+   +LQ +    +    E E + ++L   KQ L + L +L+ ++EEE +    + +
Sbjct: 1276 DLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAH 1335

Query: 944  EKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKE-KK 1002
              +  +     L EQ +EE+ A+ +LQ     A +++ +   +      Q ++ ++E KK
Sbjct: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395

Query: 1003 LMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDG 1062
             +  R+ E          K  +L K + + +  + DL   L++       L+K +R  D 
Sbjct: 1396 KLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDK 1455

Query: 1063 ETTDLQDQIAELQAQIDELKLQLAKKEEEL---QGALARGDD--ETLHKNNALKVVRELQ 1117
               + + ++ E QA+++  + +      EL   + A     D  ETL + N     + LQ
Sbjct: 1456 VLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN-----KNLQ 1510

Query: 1118 AQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVA 1177
             +I++L E       +  +AEK K+ + +E   L+  LE+   +   ++    + + E++
Sbjct: 1511 EEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELS 1570

Query: 1178 ELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELA 1237
            ++K  L+ +    + +I+ +++    A E L   L+   R + +  + K+ +E D  E+ 
Sbjct: 1571 QVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEME 1630

Query: 1238 CEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQN-------ELD 1290
             ++    +  AE++   + +  Q+++    + +  R   +L E+ + ++        EL+
Sbjct: 1631 IQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELE 1690

Query: 1291 NVSTLLEEAEKKGIKFAKDA--ASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSL 1348
             +   LE+ E+      ++   AS   QL  +Q      T++KL       Q E E NS+
Sbjct: 1691 EMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVE-NSI 1749

Query: 1349 QEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRL 1408
            QE +  EE+A+K +    +     +A+  KK  D    +E +++  ++ +KD +      
Sbjct: 1750 QESRNAEEKAKKAITDAAM-----MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1804

Query: 1409 EEKALAYDK--LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF------------- 1453
            E+ AL   K  ++K +NR+++  ++L V+     +      K ++K              
Sbjct: 1805 EQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKN 1864

Query: 1454 --------DQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQ 1505
                    D+L A+ KS    Y  + + AE +A  + ++   +   LEEA E  +  E Q
Sbjct: 1865 ILRLQDLVDKLQAKVKS----YKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQ 1920

Query: 1506 NKQLRADMEDLMSSK 1520
              +LRA   D+ S K
Sbjct: 1921 VNKLRAKSRDVGSQK 1935



 Score =  115 bits (288), Expect = 4e-25
 Identities = 123/561 (21%), Positives = 262/561 (46%), Gaps = 72/561 (12%)

Query: 844  LLQVTRQEEELQAKDEELLKVKEK-QTKVEGELEEMERKHQQL--LEEKNILAEQLQAET 900
            L +     E   +K   L K K++ Q +VE  + ++ER H     L++K    +++ AE 
Sbjct: 1401 LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEW 1460

Query: 901  ELFAEAEEMRARLAAKKQELEEI---LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE 957
            +   + +E +A L A ++E   +   L  + +  EE  ++ + L+ E K +Q  I DL E
Sbjct: 1461 K--QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTE 1518

Query: 958  Q-------LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAE 1010
            Q       L E E  ++ ++ EK   +  ++++E     LE + SK ++ +  +    +E
Sbjct: 1519 QIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGS---LEHEESKILRVQLELSQVKSE 1575

Query: 1011 CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQ 1070
               ++ E++E+ + L   RN Q    + L+  L  E ++R +  + K+K++G+       
Sbjct: 1576 LDRKVIEKDEEIEQLK--RNSQRAAEA-LQSVLDAEIRSRNDALRLKKKMEGD------- 1625

Query: 1071 IAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQ------ 1124
            + E++ Q+     Q+A+ ++ L+    +  D  LH ++AL+   +L+ Q+A ++      
Sbjct: 1626 LNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLL 1685

Query: 1125 -EDFESEKASRNKAEKQKR-------DLSEELEAL---------------------KTEL 1155
             E+ E  K +  + E+ +R       D S+ ++ L                     + E+
Sbjct: 1686 LEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745

Query: 1156 EDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQA 1215
            E+++  +   +E   K   + A + + L++E ++  A ++ M++     +++L  +L++A
Sbjct: 1746 ENSIQESRNAEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEA 1804

Query: 1216 KRFKANLEKNK-QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRL 1274
            ++      K + Q LE   +EL  E+ V Q+  AE+     K + +V+E+  +  E  + 
Sbjct: 1805 EQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKN 1864

Query: 1275 RVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNL 1334
             + L +   KLQ ++ +     EEAE++       A +  S+ +  Q  L+E   +    
Sbjct: 1865 ILRLQDLVDKLQAKVKSYKRQAEEAEEQ-------ANTQLSRCRRVQHELEEAAERADIA 1917

Query: 1335 SSRIRQLEEEKNSLQEQQEEE 1355
             S++ +L  +   +  Q+ EE
Sbjct: 1918 ESQVNKLRAKSRDVGSQKMEE 1938


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 1255 bits (3247), Expect = 0.0
 Identities = 713/1907 (37%), Positives = 1115/1907 (58%), Gaps = 24/1907 (1%)

Query: 33   KKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAE 92
            KK  WIP   + +  A +K    D  ++    +G+   + +D IQ+MNPP+F  +EDMA 
Sbjct: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110

Query: 93   LTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPP 152
            LT LNEASVLH LK RY   +IYTYSGLFCV INPYK LP+Y + ++  Y+GK+R E PP
Sbjct: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170

Query: 153  HIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPG 212
            HI+A++ +A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + RK     G
Sbjct: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ---G 227

Query: 213  ELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAV 272
             LE Q++QAN ILE+FGNAKT++NDNSSRFGKFIR++F   G +   +I+ YLLEKSR +
Sbjct: 228  ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287

Query: 273  RQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN--NYRFLSNGYIPIPGQQDKDNFQETM 330
             Q   ER +HIFYQ+LSG  E    DLLL   N  ++ F S G + +    D +    T 
Sbjct: 288  FQQAGERNYHIFYQILSGQKE--LHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATE 345

Query: 331  EAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVM 390
            +AM I+GF  +E     K+  +++ FGN+ FK++   +Q        A K   L+G+N  
Sbjct: 346  QAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSS 405

Query: 391  EFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQ 450
            E  + ++ PRIKVG +YV + QT EQ   AV AL+K+ YER+F+WLV RIN+ALD  K  
Sbjct: 406  ELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALD-AKLS 464

Query: 451  GASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFID 510
               FIGILDI GFEI E NS EQLCIN+TNEKLQQ FN  MF+LEQEEY++E IEW  I 
Sbjct: 465  RQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIG 524

Query: 511  FGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQKPRQL 569
            FGLDLQ CIDLIE+P    G+L++L+EEC FPKATD TF  KL     G     QKP+  
Sbjct: 525  FGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPD 581

Query: 570  KDK--ADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVG 627
            K K  A F ++HYAG V Y    WL KN D LN+ V  +  +SS+R +A L+++      
Sbjct: 582  KKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENY----- 636

Query: 628  LDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRA 687
               ++  +   FG   + K   F+TV  L+KE+L KLM  L++T P+FVRCI PN  K  
Sbjct: 637  ---MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIP 693

Query: 688  GKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG-FMDGKQA 746
            G LDP+LVL QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL P   PK  F+  ++A
Sbjct: 694  GILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKA 753

Query: 747  CERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAF 806
             E ++ +LE+D   YR G +K+FF+AG L  LE  RD +++ +   FQA  +G L R  F
Sbjct: 754  AEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKF 813

Query: 807  AKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKE 866
             K  ++  AL ++Q N  A++ +++W W R+F K+KPL++ +   EE+    EE  ++++
Sbjct: 814  QKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQK 873

Query: 867  KQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHD 926
               K E + EE++ K   L +EKN L  QLQAE E  A  EE    L   K +LE  + +
Sbjct: 874  ALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKE 933

Query: 927  LESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEE 986
            L  RVEEEEE N  L    +K++    +L++++D+ E    K + EK T E K+K + EE
Sbjct: 934  LSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEE 993

Query: 987  ILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKE 1046
            +  L +  SK  +  K++++   +    L  EEEK  +L+K   K E  + +LE  L++E
Sbjct: 994  VEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQE 1053

Query: 1047 EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHK 1106
             K R   E+   KL+G     ++ +  L++    L  +L KKE EL    ++ ++E    
Sbjct: 1054 RKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLV 1113

Query: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166
                K V+ELQ QI +L+E  E+E+ +R K E+++ DL+++L  L   LE+   ++ AQ 
Sbjct: 1114 AQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQL 1173

Query: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
            E+  K+E +  +L + +EE T + E     +++RHA +L EL  Q+E  ++ K  LEK+K
Sbjct: 1174 EITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDK 1233

Query: 1227 QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQ 1286
              L+ +  +L   V+ + + KA +E      + ++ E  AK+ +  +L  +LA + +KL 
Sbjct: 1234 SDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLW 1293

Query: 1287 NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN 1346
            +E       LEE E    + +++ ++   Q++D +  L++ET+ +  L+  +++ + + +
Sbjct: 1294 SESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCD 1353

Query: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKKKLLKDAEALS 1405
             L+EQ EEE+E +  L + +  + +++   + K +++ +   E LE+AKK+L    +  +
Sbjct: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413

Query: 1406 QRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISA 1465
            + +         LE+ +++LQ EL D   DL   R  A+ L++KQ +  + LA+ K    
Sbjct: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHE 1473

Query: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525
                  D ++ E +   T+ L L    EE++  +E   R+NK L+ ++ +L +   +  K
Sbjct: 1474 ESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTK 1533

Query: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
            N+ E+EK K+ +E++  E++  LEE E  L+  E   L  ++ +   KA+ ER L  +DE
Sbjct: 1534 NLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDE 1593

Query: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645
            + E  +R     +  L++ L+ E K R      KKKME DL ++E Q+  AN+   E  K
Sbjct: 1594 EIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATK 1653

Query: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705
             L +LQ Q+KD Q +L+++     ++  Q   +E++   L++E+  L+     +ER RR 
Sbjct: 1654 SLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRL 1713

Query: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765
            +E+E  E  + I    +  ++LL +K++LEA +A++++E EE     +   ++ +K  ++
Sbjct: 1714 SEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIE 1773

Query: 1766 VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ 1825
               L+ EL  ++      +  R+ +E+   +L+ +L E E       +  I  LE+++ +
Sbjct: 1774 AANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRE 1833

Query: 1826 LEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQ 1885
            LE +LE E +  A A +  RR E+ +KE+  Q E+++++  + + QM+K   +++  K+Q
Sbjct: 1834 LEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQ 1893

Query: 1886 LEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGG 1932
            +E AE +A +  +  +K Q EL++  E  E    +V+ LK + R  G
Sbjct: 1894 VEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFG 1940



 Score =  192 bits (489), Expect = 2e-48
 Identities = 179/924 (19%), Positives = 404/924 (43%), Gaps = 94/924 (10%)

Query: 850  QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909
            +EE+L +  +  LK++++  ++EG LE+  +       E + L   L+   E     E  
Sbjct: 1025 EEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESS 1084

Query: 910  RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL 969
            +  LA + ++ E  L  + S+VE E+     LQ   K++Q  I+DL+E+L+ E   R K+
Sbjct: 1085 QRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKM 1144

Query: 970  QLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL-AKI 1028
            + E+      +  + E +  +   +   ++  K  E +  +    + E     +   A +
Sbjct: 1145 ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASL 1204

Query: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKK 1088
            + +    +++LE +++  ++ +Q+LEK K  L  E  DL  ++ ++       +      
Sbjct: 1205 KKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLY 1264

Query: 1089 EEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1148
            EE L  A A+ D  T   N+      +L ++  E     E ++A  N+  ++K + + ++
Sbjct: 1265 EERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQI 1324

Query: 1149 EALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETK-------------------- 1188
            E L+ +LE    + +A      K +++   L++  EEE +                    
Sbjct: 1325 EDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWR 1384

Query: 1189 --------NHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEV 1240
                         ++D ++  A  L+E +E +  A    A+LE+ +  L+ +  +   ++
Sbjct: 1385 MKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDL 1444

Query: 1241 KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAE 1300
              ++   A  + K+ +    + +   K  E   L     ++   L  EL  +    EE+ 
Sbjct: 1445 GKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESI 1504

Query: 1301 KKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARK 1360
                   ++  +L+ ++ +    ++E T+    +    + +EEEK  +Q   EE E A +
Sbjct: 1505 VGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALE 1564

Query: 1361 NLEKQVLALQSQLADTKKKVDDDLG---------------TIESLEEA------------ 1393
              E ++L  Q +L + K +++  L                TI+SL+ +            
Sbjct: 1565 RNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVT 1624

Query: 1394 --KKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKK-- 1449
              KKK+ +D   +  +L        +  K+  +LQ ++ DL + LD   Q+ S+L+++  
Sbjct: 1625 RLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVA 1684

Query: 1450 ---------QKKFDQLLA-EEKSISARYAEERDRAEAEAR-------------EKETKAL 1486
                     Q + + L + +E++   R   E +  EA  R             +K+    
Sbjct: 1685 VAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEA 1744

Query: 1487 SLARALEEALEAKEEFERQNKQLR------ADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
             +AR  +EA E  +E +   ++ +      A++ + +  K D    +  LE+++  +EQ 
Sbjct: 1745 DVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDT---IAHLERTRENMEQT 1801

Query: 1541 VEEMRTQLEELED-ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVR 1599
            + +++ +L E E   L  +     +LE  ++ ++ + E +++ R  + +   R L + ++
Sbjct: 1802 ITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIR-RSAEAQRGARRLERCIK 1860

Query: 1600 ELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659
            EL  + E+++K  +       K+++ +++ + Q+E A    ++ + + +K Q ++ + + 
Sbjct: 1861 ELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKE 1920

Query: 1660 ELEEARASRDEIFAQSKESEKKLK 1683
              E A +  +++  +++E  KK++
Sbjct: 1921 RAEVAESQVNKLKIKAREFGKKVQ 1944



 Score =  112 bits (280), Expect = 4e-24
 Identities = 109/481 (22%), Positives = 207/481 (43%), Gaps = 30/481 (6%)

Query: 851  EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
            ++E+QA   ELLK+K    +     E + R+++ L EE + L  Q++  T+   E E+++
Sbjct: 1483 QKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVK 1542

Query: 911  ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EGARQKL 969
              +  +K E++  L + E  +E  E +    Q E  + +A ++    + DEE E  R+K 
Sbjct: 1543 KLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQ 1602

Query: 970  QLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIR 1029
            Q    T ++    ++ E         +  + KK ME+ + E   QL+    +     K  
Sbjct: 1603 QC---TIDSLQSSLDSEA----KSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSL 1655

Query: 1030 NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKE 1089
             + ++ I DL+ +L    +   +L++     +   + LQ ++ +L++  ++ +      E
Sbjct: 1656 GQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSE 1715

Query: 1090 EELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
            EEL  A  R +       + L   ++L+A +A +Q++ E        AE++ +  + E  
Sbjct: 1716 EELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAA 1775

Query: 1150 ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELS 1209
             L  EL+   DT A  +  R   EQ + +L+K L E  +      +   Q+  + + EL 
Sbjct: 1776 NLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELE 1835

Query: 1210 EQLEQAKRFKANLEKNKQGLET-----------DNKELACEVKVLQQVKAESEHKRKKLD 1258
             +LE   R  A  ++  + LE            D K L           +  + +  KL 
Sbjct: 1836 GELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL-----------SRMQTQMDKLQ 1884

Query: 1259 AQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQ 1318
             +VQ    +V   +    +   K  K Q+EL+ V    E AE +  K    A     ++Q
Sbjct: 1885 LKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQ 1944

Query: 1319 D 1319
            +
Sbjct: 1945 E 1945



 Score = 38.1 bits (87), Expect = 0.086
 Identities = 31/140 (22%), Positives = 70/140 (50%), Gaps = 9/140 (6%)

Query: 850  QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909
            ++  L    +++ K++ +  ++EGELE   R+  +       L   ++   EL  +AEE 
Sbjct: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQAEED 1869

Query: 910  RARLAAKKQELEEI---LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966
            +  L+  + +++++   + + + +VE  E +     ++ KK Q  + +++E+ +  E   
Sbjct: 1870 KKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQV 1929

Query: 967  QKLQLEKVTAEAKIKKMEEE 986
             KL   K+ A    KK++EE
Sbjct: 1930 NKL---KIKAREFGKKVQEE 1946


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  587 bits (1514), Expect = e-167
 Identities = 444/1432 (31%), Positives = 713/1432 (49%), Gaps = 157/1432 (10%)

Query: 30   WTAKKLVWIPSERHGFEAASIKEER--GDEVMVELAENGKKA--MVNKDDIQKM-NPPKF 84
            +T    VWIP     +++A I ++   GD+V+  L E+G +    VN + +  + NP   
Sbjct: 7    YTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDIL 66

Query: 85   SKVEDMAELTCLNEASVLHNLKDRYY-SGLIYTYSGLFCVVINPYKNLPIYSENIIEMYR 143
                D+  L+ L+E +VLHNL+ R+  S LIYTYSG+  V +NPYK LPIY + II  Y 
Sbjct: 67   VGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYS 126

Query: 144  GKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK 203
            G+   +M PHI+A++E AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S  
Sbjct: 127  GQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKS-- 184

Query: 204  GRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIET 263
            G   H     +E ++L +NPI E+ GNAKT +NDNSSRFGK+  I+FD    I+GAN+ T
Sbjct: 185  GSNAH-----VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMST 239

Query: 264  YLLEKSRAVRQAKDERTFHIFYQLLSGAGE----HLKSDLLLEGFNNYRFLSNGYIPIPG 319
            YLLEKSR V Q+++ER +HIFYQL + A +    HLK     E FN  R    G   I G
Sbjct: 240  YLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLG-SAEEFNYTRM--GGNTVIEG 296

Query: 320  QQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQ 379
              D+    ET +   ++GF  +  + + K+++++L  GN+      N   +   +++  +
Sbjct: 297  VNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLK 356

Query: 380  KLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHR 439
              C LLG+      + +   +I    + V K  T+ QA  A +ALAK  Y  LF ++V R
Sbjct: 357  VFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVER 416

Query: 440  INKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
            IN+AL  + +Q  +FIG+LDI GFE F++NSFEQ CINY NEKLQQ FN  +F LEQEEY
Sbjct: 417  INQALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEY 475

Query: 500  QREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQE-QG 558
             +E I W  IDF  D QP IDLIE      G+L LLDEEC  P  TD+ +++KL      
Sbjct: 476  MKEDIPWTLIDF-YDNQPVIDLIEAKM---GILELLDEECLLPHGTDENWLQKLYNNFVN 531

Query: 559  SHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAEL 618
             +  F+KPR       F I H+A KV+YK + +L KN D + D +  +L  S     A  
Sbjct: 532  RNPLFEKPRM--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANF 589

Query: 619  WKDVDRIVGLDQVTGMTETAFGSAYKTK----------KGMFRTVGQLYKESLTKLMATL 668
            +          Q      + FGS    K          K    TVG  ++ SL  LM TL
Sbjct: 590  F----------QENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETL 639

Query: 669  RNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRY 728
              T P++VRCI PN EK   + D   ++ QLR  GVLE IRI  Q +P+R  + EF  RY
Sbjct: 640  NATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRY 699

Query: 729  EILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITD 788
             IL        F D K+ C+ ++  L  D N Y+ G++KIFFRAG +A+LE+ R  K+  
Sbjct: 700  GILMTKQ-ELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQ 758

Query: 789  IIIFFQAVCRGYLARKAFAKKQ-------------------------QQLSALKVLQRNC 823
              +  Q   RG+L RK F +++                         ++  A  ++Q++C
Sbjct: 759  SCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHC 818

Query: 824  AAYLKLRHWQWWRVFTKVKPLLQVTRQEE-ELQAKDEELLKVKEKQTKVEGELEEMERKH 882
              YL             V+ L Q+ R     +QA     L                 R++
Sbjct: 819  RGYL-------------VRSLYQLIRMATITMQAYSRGFL---------------ARRRY 850

Query: 883  QQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQ 942
            +++LEE   +  Q  A   L A       R      +L   +  L+ ++E++ + N  L 
Sbjct: 851  RKMLEEHKAVILQKYARAWL-ARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLV 909

Query: 943  NEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKK----MEEEILLLEDQNSKFI 998
             +   + A      E++ + E   +K    +   E K K+    +EE++  L+  NS+  
Sbjct: 910  EKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELE 969

Query: 999  KEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 1058
             +K+ ++ ++ E + +L   +EK  NL K           L + ++KEE+ R  LEK+  
Sbjct: 970  TQKEQIQLKLQEKTEEL---KEKMDNLTK----------QLFDDVQKEERQRMLLEKS-- 1014

Query: 1059 KLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDD---ETLHKNNALKVVRE 1115
              + +T D + QI  L+ +I  LK +  + +  ++G     D    E    +  +K + E
Sbjct: 1015 -FELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISE 1073

Query: 1116 LQAQIAELQ-EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174
             + +I  LQ +  + EK      + QKR++ E++  +  +L ++ D    +  L  +  +
Sbjct: 1074 FEKEIELLQAQKIDVEK----HVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLE 1129

Query: 1175 EVAE------LKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQG 1228
             + E        + L++ T+  E+  Q  +  +   +E L+ ++    +   +L+K  + 
Sbjct: 1130 HLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFRE 1189

Query: 1229 LETDNKELACEVKVLQQVKAESEHKR-KKLDAQVQELHAKVSEGDRLRVELAEKASKLQN 1287
                N+ +  EV      +  SE+        Q+ EL  +  +   L + L E+A K++ 
Sbjct: 1190 ENDINESIRHEV-----TRLTSENMMIPDFKQQISELEKQKQD---LEIRLNEQAEKMKG 1241

Query: 1288 ELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNS 1347
            +L+ +S  L  ++       ++  +    L+   E+    T++K  L  +I++++E  + 
Sbjct: 1242 KLEELSNQLHRSQ-------EEEGTQRKALEAQNEI---HTKEKEKLIDKIQEMQEASDH 1291

Query: 1348 LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLK 1399
            L++Q E E E + N  ++   L  +  D ++++D     I+ L++  K L K
Sbjct: 1292 LKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSK 1343



 Score =  103 bits (258), Expect = 1e-21
 Identities = 136/594 (22%), Positives = 270/594 (45%), Gaps = 121/594 (20%)

Query: 791  IFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFT-KVKPLLQVTR 849
            I  QA  RG+LAR+ + K  ++  A+ +LQ+   A+L  R +Q  R F   ++   +V R
Sbjct: 835  ITMQAYSRGFLARRRYRKMLEEHKAV-ILQKYARAWLARRRFQSIRRFVLNIQLTYRVQR 893

Query: 850  QEEELQAKDEELLKVKEKQT--------------KVEGELE----------EMERKHQQL 885
             +++L+ +++E   + EK T              K+E ELE          E  ++++  
Sbjct: 894  LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDA 953

Query: 886  LEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESR----VEEEEERNQIL 941
            +EEK  LA+  +  +EL  + E+++ +L  K +EL+E + +L  +    V++EE +  +L
Sbjct: 954  VEEK--LAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLL 1011

Query: 942  QN----EKKKMQAHIQDLEEQL----DEEEGARQKLQLEKVTAEA-------------KI 980
            +     + +  +  IQ L+E++    DE+   +  ++ E VT++               I
Sbjct: 1012 EKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTI 1071

Query: 981  KKMEEEILLLEDQNSKFIK----EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMI 1036
             + E+EI LL+ Q     K    +K+ M ++++E + QL E  +    +  +R++  + +
Sbjct: 1072 SEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYD----IEDVRSR--LSV 1125

Query: 1037 SDLE------------ERLKKEEKTRQE-LEKAKRKLDGETTDLQDQIAELQAQIDELKL 1083
             DLE            E LKK  +  +   +  K   + E   L  ++  L  +I+ L+ 
Sbjct: 1126 EDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQ- 1184

Query: 1084 QLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRD 1143
            +L ++E ++  ++     E     +   ++ + + QI+EL              EKQK+D
Sbjct: 1185 KLFREENDINESIRH---EVTRLTSENMMIPDFKQQISEL--------------EKQKQD 1227

Query: 1144 ----LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH---EAQIQD 1196
                L+E+ E +K +LE+         +L   +E+E  + +KALE + + H   + ++ D
Sbjct: 1228 LEIRLNEQAEKMKGKLEE------LSNQLHRSQEEEGTQ-RKALEAQNEIHTKEKEKLID 1280

Query: 1197 MRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKK 1256
              Q    A + L +Q E     K N  +    L  +N++L  E+ +  +V        KK
Sbjct: 1281 KIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRV-------IKK 1333

Query: 1257 LDAQVQELHAKVSEGDRLRVELAEK------ASKLQNELDNVSTLLEEAEKKGI 1304
            L  QV+ L   + + + +      K        K ++E   +  L+ + + +G+
Sbjct: 1334 LQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKLIQNLILDLKPRGV 1387



 Score = 89.0 bits (219), Expect = 4e-17
 Identities = 106/480 (22%), Positives = 220/480 (45%), Gaps = 77/480 (16%)

Query: 1245 QVKAESEHKRKKLDAQVQELHA---KVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEK 1301
            Q+    +  +KKL+ Q +E H    K++    LR    EK  KL+ EL+  +T     E+
Sbjct: 886  QLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEE 945

Query: 1302 KG-----------IKFAKDAASLESQLQDTQELLQEETRQ-KLNLSSRIRQL------EE 1343
            KG            K  K  + LE+Q +  Q  LQE+T + K  + +  +QL      EE
Sbjct: 946  KGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEE 1005

Query: 1344 EKNSLQEQQ-----EEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLL 1398
             +  L E+      ++ E+  ++L++++ AL+ +    +  V+ +  T + L+    +L 
Sbjct: 1006 RQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLS 1065

Query: 1399 KDAEALS------QRLEEKALAYDK-LEKTKNRLQQELDDLTVDL--------DHQRQVA 1443
            K  + +S      + L+ + +  +K ++  K  +++++ ++T  L           R   
Sbjct: 1066 KQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSV 1125

Query: 1444 SNLEKKQK------KFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
             +LE   +       ++ L    + + + +  ++D  E E      K + L++ +    +
Sbjct: 1126 EDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQK 1185

Query: 1498 AKEEFERQNKQLRADMEDLMSSK---DDVGKNVHELEKSKRALE----QQVEEMRTQLEE 1550
               E    N+ +R ++  L S      D  + + ELEK K+ LE    +Q E+M+ +LEE
Sbjct: 1186 LFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEE 1245

Query: 1551 LEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL--IKQVRE----LEAE 1604
            L ++L  +++     E   Q    + + ++ T+     EK++L+  I++++E    L+ +
Sbjct: 1246 LSNQLHRSQE-----EEGTQRKALEAQNEIHTK-----EKEKLIDKIQEMQEASDHLKKQ 1295

Query: 1605 LEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEA 1664
             E E + +        ++ ++ +DLE +++     +D VIK   KLQ Q+K   + + +A
Sbjct: 1296 FETESEVKCNFRQEASRLTLENRDLEEELD----MKDRVIK---KLQDQVKTLSKTIGKA 1348



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 93/498 (18%), Positives = 221/498 (44%), Gaps = 82/498 (16%)

Query: 1176 VAELKKALEEETKNHEAQIQDM------RQRHATALEELSEQLEQA-----------KRF 1218
            V  L+K LE++ K +   ++ +      R      +++L  +LE+A           KR+
Sbjct: 891  VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRY 950

Query: 1219 KANLEKNKQGLETDNKELACEVKVLQ-QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277
            +  +E+    L+  N EL  + + +Q +++ ++E  ++K+D   ++L   V + +R R+ 
Sbjct: 951  RDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRM- 1009

Query: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337
            L EK+ +L+ +         + EK+     ++  +L+ +    Q L++ E      L + 
Sbjct: 1010 LLEKSFELKTQ---------DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAE 1060

Query: 1338 IRQLEEEKNSLQEQQEEEE--EARK-NLEKQVLALQSQLADTKKKVDDDLGTIESLEEAK 1394
            + +L ++  ++ E ++E E  +A+K ++EK V + + ++ +   ++   L     +E+ +
Sbjct: 1061 VARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVR 1120

Query: 1395 KKL-LKDAEALSQRLEEKALAYDKLEKT-----------KNRLQQELDDLTVDLDHQRQV 1442
             +L ++D E L++   E   AY+ L+K            K+  ++E++ L   + H  Q 
Sbjct: 1121 SRLSVEDLEHLNED-GELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQE 1179

Query: 1443 ASNLEKK----------------------------QKKFDQLLAEEKSISARYAEERDRA 1474
             ++L+K                             +++  +L  +++ +  R  E+ ++ 
Sbjct: 1180 INHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKM 1239

Query: 1475 EAEAREKETKALSLARALEE------ALEAKEEFERQNKQLRAD-MEDLMSSKDDVGKNV 1527
            + +  E   +   L R+ EE      ALEA+ E   + K+   D ++++  + D + K  
Sbjct: 1240 KGKLEELSNQ---LHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQF 1296

Query: 1528 HELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN 1587
                + K    Q+   +  +  +LE+EL   +    +L+  ++ +     +         
Sbjct: 1297 ETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSG 1356

Query: 1588 EEKKRLLIKQVRELEAEL 1605
             ++   +++  RE EA+L
Sbjct: 1357 PKEYLGMLQYKREDEAKL 1374



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 101/493 (20%), Positives = 206/493 (41%), Gaps = 69/493 (13%)

Query: 1528 HELEKSKRALEQQVEEMRTQLEELED--ELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
            + +++ ++ LE Q +E    +E+L     L+A +  K+      Q ++A+ E+   T   
Sbjct: 889  YRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKI------QKLEAELEK-AATHRR 941

Query: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645
              EEK +     V E  A+L+    +        +K +I LK L+ + E   +  D + K
Sbjct: 942  NYEEKGKRYRDAVEEKLAKLQKHNSE-----LETQKEQIQLK-LQEKTEELKEKMDNLTK 995

Query: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705
            QL        D Q+E  +          ++++ EK+++SL+ EI  L++E    +     
Sbjct: 996  QL------FDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEG 1049

Query: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765
                 D L  E+   +     + + ++ +E   AQ  +  +  QS    + ++  + T Q
Sbjct: 1050 EHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQ 1109

Query: 1766 ------VDTLNAELAAERSAAQKSDN----ARQQLERQNKELKAKLQELEGAVKSKFKAT 1815
                  ++ + + L+ E       D     A + L++  + L++  Q    + K  ++  
Sbjct: 1110 LLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQ----SQKDCYEKE 1165

Query: 1816 ISALEAKIGQLEEQ---LEQEAKERAAANKLVRRTEKKLKEIFMQVED--------ERRH 1864
            I AL  K+  L ++   L++  +E    N+ +R    +L    M + D        E++ 
Sbjct: 1166 IEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQK 1225

Query: 1865 AD---QYKEQMEKANARMKQLKRQLEEA-EEEATRANA----------SRRKLQRELDDA 1910
             D   +  EQ EK   ++++L  QL  + EEE T+  A           + KL  ++ + 
Sbjct: 1226 QDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEM 1285

Query: 1911 TEANEGLSREVST---LKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDD------TE 1961
             EA++ L ++  T   +K   R+        +R    +L ++   ++   D       T 
Sbjct: 1286 QEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345

Query: 1962 SKTSDVNETQPPQ 1974
             K +DV+ +  P+
Sbjct: 1346 GKANDVHSSSGPK 1358



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 83/386 (21%), Positives = 159/386 (41%), Gaps = 56/386 (14%)

Query: 1596 KQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKL----- 1650
            K +RE  A L  ++  R      K    + LK+  A I      R  +++ L +L     
Sbjct: 775  KFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMAT 834

Query: 1651 ---QAQMKD------YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSER 1701
               QA  +       Y++ LEE +A   + +A++  + ++ +S+   +L +Q        
Sbjct: 835  ITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRL 894

Query: 1702 ARRHAEQERDE--LADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRF 1759
             ++  +Q ++   L +++T+ A+ ++  +++ ++LEA + +        +   +   D  
Sbjct: 895  QKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAV 954

Query: 1760 RKTTLQVDTLNAELAAERSAAQ------------KSDNARQQL-------ERQ----NKE 1796
             +   ++   N+EL  ++   Q            K DN  +QL       ERQ     K 
Sbjct: 955  EEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKS 1014

Query: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEI-- 1854
             + K Q+ E  ++S  K  I AL+ +  QL+  +E E          V R  K++K I  
Sbjct: 1015 FELKTQDYEKQIQS-LKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISE 1073

Query: 1855 ---------FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQR 1905
                       +++ E+    Q +E  EK +   KQL   LE  + E  R+  S   L+ 
Sbjct: 1074 FEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQL---LESYDIEDVRSRLSVEDLEH 1130

Query: 1906 ELDDAT--EANEGLSREVSTLKNRLR 1929
              +D     A EGL +    L++  +
Sbjct: 1131 LNEDGELWFAYEGLKKATRVLESHFQ 1156


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  587 bits (1513), Expect = e-167
 Identities = 461/1471 (31%), Positives = 735/1471 (49%), Gaps = 115/1471 (7%)

Query: 36   VWIPSERHGFEAASIKEER--GDEVMVELAENGKKAMVNKDDIQK-----MNPPKFSKVE 88
            VWIP     +++A + ++   GD+V++   E GK    + D   K      NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 89   DMAELTCLNEASVLHNLKDRYY-SGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKR 147
            D+  L+ L+E +VLHNL+ R+  S LIYTY G+  V INPY+ LPIY E+II  Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 148  HEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKD 207
             +M PHI+A++E AY+ M +D  +QSI+ +GESGAGKT + K  ++Y A V+ S      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188

Query: 208  HNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
                  +E ++L +NPI+ES GNAKT +NDNSSRFGK+I I FD    I+GAN+ TYLLE
Sbjct: 189  ---EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245

Query: 268  KSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIP-IPGQQDKDNF 326
            KSR V QA++ER +HIFYQL + A       L L   +N+ +   G  P I G  D    
Sbjct: 246  KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305

Query: 327  QETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASM-PENTVAQKLCHLL 385
              T +A  ++G S    + + ++++ +L  GN+ F   R+ D  ++ P++      C L+
Sbjct: 306  AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364

Query: 386  GMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALD 445
            G++  E    +   ++    +   K  +K QA  A +ALAK  Y +LF W+V  +N+AL 
Sbjct: 365  GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424

Query: 446  RTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
               +Q  SFIG+LDI GFE FE+NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I 
Sbjct: 425  SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483

Query: 506  WNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQ 564
            W  IDF  D QPCI+LIE   +  G+L LLDEEC  PK TD T+ +KL        + F+
Sbjct: 484  WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539

Query: 565  KPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDR 624
            KPR L +KA F I H+A KV+Y+ + +L KN D + +    +L  S  + + EL++D ++
Sbjct: 540  KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597

Query: 625  IVGLDQVT--GMTETAFGSAYKTK-------KGMFRTVGQLYKESLTKLMATLRNTNPNF 675
             +     T  G T      A  TK       K   +TVG  ++ SL  LM TL  T P++
Sbjct: 598  AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657

Query: 676  VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA 735
            VRCI PN  K     D    + QLR  GVLE IRI   GFP+R  +QEF  RY +L    
Sbjct: 658  VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716

Query: 736  IPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQA 795
                  D KQ C+ ++  L LD + Y+ G++KIFFRAG +A+LE+ R  K+    I  Q 
Sbjct: 717  -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775

Query: 796  VCRGYLARKAFAKKQQQLSAL-------------KVLQRNCAAYLKLRHWQWWRVFTKVK 842
              RG+L RK + + ++    +             K L+R  AA +  ++W+         
Sbjct: 776  TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWR--------- 826

Query: 843  PLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETEL 902
              + V R+  +++     +L+   +         ++ R+H+ ++ +K +     +   + 
Sbjct: 827  --MYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKR 884

Query: 903  FAEA---EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
               A    +   R    K+EL+++   +E+R  E  ++  I       M+  I  L+ ++
Sbjct: 885  SMHAIIYLQCCFRRMMAKRELKKL--KIEARSVERYKKLHI------GMENKIMQLQRKV 936

Query: 960  DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEK-KLMEDRIAECSSQLAEE 1018
            D E+    K  +EK+T    I   E E L  + +  +  +E+ K+   R+     ++A  
Sbjct: 937  D-EQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIA-- 993

Query: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
             +  K+L + R++++ +    +   ++ E+    L++    L  E   L  +I +   ++
Sbjct: 994  -KLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM 1052

Query: 1079 DE-LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA 1137
             E ++ +L ++ ++L+  L   +DE L   N L     L+ +  +L+E+  +      K 
Sbjct: 1053 TETMEKKLVEETKQLELDL---NDERLRYQNLLNEFSRLEERYDDLKEEM-TLMVHVPKP 1108

Query: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET-KNHEAQIQD 1196
              ++ D +        E E    +  A+ E    R +E +E K  L+       + ++ +
Sbjct: 1109 GHKRTDSTHS----SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164

Query: 1197 MRQRHATALEELSEQLEQAKRFKANLEKNKQ--GLETDNKELACEVKVLQQVKAESEHKR 1254
            + Q      +EL  + EQ  R KA  E+  Q  G E + + L          + E E + 
Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLK---------RQELESEN 1215

Query: 1255 KKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLE 1314
            KKL  ++ EL   +SE     V  A  A   +  ++ ++++ EE + +     ++   L 
Sbjct: 1216 KKLKNELNELRKALSEKSAPEV-TAPGAPAYRVLMEQLTSVSEELDVR----KEEVLILR 1270

Query: 1315 SQLQDTQELLQEETRQKLNLSSRIR----QLEEEKNSLQEQQEEEEEARKNLEKQVLALQ 1370
            SQL   +E +Q +  +     S I     Q  ++K  + +     +E  + LE Q   LQ
Sbjct: 1271 SQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQ---LQ 1327

Query: 1371 SQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE--EKALAYDKLEKTKNRLQQE 1428
            SQ    + + +   G I+SL+E      +  + L+Q L+   +A     L+    RL  E
Sbjct: 1328 SQKRSHENEAEALRGEIQSLKEENN---RQQQLLAQNLQLPPEARIEASLQHEITRLTNE 1384

Query: 1429 LDDLTVDLDHQRQVASNLEKKQKKFDQLLAE 1459
              DL   L+ Q +    L+K+ K F + + E
Sbjct: 1385 NLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1415



 Score = 85.5 bits (210), Expect = 5e-16
 Identities = 167/766 (21%), Positives = 308/766 (40%), Gaps = 119/766 (15%)

Query: 1197 MRQRHATALEELSEQLEQAKRFKANLEKN----KQGLETDNKELACEVKVLQQVK----A 1248
            M +R    L+  +  +E+ K+    +E      ++ ++  NK+  C V+ L  ++    +
Sbjct: 900  MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959

Query: 1249 ESEHKRKKLDA-QVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
            E+E  R  L+  Q+ E  AKV+ G  L   L E+ +KL+ +L+        +EKK I+  
Sbjct: 960  ETEKLRSDLERLQLSEEEAKVATGRVL--SLQEEIAKLRKDLEQT-----RSEKKCIEEH 1012

Query: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
             D        Q+T++L+        NL        +E+N+L +Q++E             
Sbjct: 1013 ADRYK-----QETEQLVS-------NL--------KEENTLLKQEKE------------- 1039

Query: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ 1427
            AL  ++    K         E  E  +KKL+++ + L   L ++ L Y  L    +RL++
Sbjct: 1040 ALNHRIVQQAK---------EMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEE 1090

Query: 1428 ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD---RAEAEAREKETK 1484
              DDL  ++     V     K+          E   S+  AE  D   R E  + +K   
Sbjct: 1091 RYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPL 1150

Query: 1485 ALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEM 1544
             +SL   L++ +   E    Q KQ+   M+D +  K++         K+K     Q+   
Sbjct: 1151 DMSLFLKLQKRVTELE----QEKQV---MQDELDRKEEQVLR----SKAKEEERPQIRGA 1199

Query: 1545 RTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAE 1604
              + E L+ +   +E+ KL+ E+N +  KA  E+             R+L++Q+  +  E
Sbjct: 1200 ELEYESLKRQELESENKKLKNELN-ELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEE 1258

Query: 1605 LEDERKQRALAVASK---KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL 1661
            L D RK+  L + S+   +K  I  KD +  +  +    ++V K   K +   + Y    
Sbjct: 1259 L-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEI-AQAYIGLK 1316

Query: 1662 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 1721
            E  R    ++ +Q +  E + ++L  EI  L+EE         + +Q+      ++   A
Sbjct: 1317 ETNRLLESQLQSQKRSHENEAEALRGEIQSLKEE--------NNRQQQLLAQNLQLPPEA 1368

Query: 1722 SGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ 1781
              +++L  E  RL      L E+LE++   +  L  + +    ++  L        S  Q
Sbjct: 1369 RIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQ 1428

Query: 1782 KSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAAN 1841
              D   + +    KE     ++ +G ++ K        +    +L + L  E K R  A 
Sbjct: 1429 IIDEPIRPVNIPRKE-----KDFQGMLEYK--------KEDEQKLVKNLILELKPRGVAV 1475

Query: 1842 KLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRR 1901
             L+      +  +FM V    RHAD Y    +K  + +              +  N+ ++
Sbjct: 1476 NLIPGLPAYI--LFMCV----RHAD-YLNDDQKVRSLL-------------TSTINSIKK 1515

Query: 1902 KLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLH 1947
             L++  DD    +  LS     L    +  G   F    + R+  H
Sbjct: 1516 VLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEH 1561


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  585 bits (1509), Expect = e-166
 Identities = 461/1520 (30%), Positives = 750/1520 (49%), Gaps = 137/1520 (9%)

Query: 36   VWIPSERHGFEAASI-KEERGDEVMVELAENGKKAMVNKDDIQK------MNPPKFSKVE 88
            VWIP     + +A + K+ +  +  ++L    +  +    D+Q+       NP       
Sbjct: 13   VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72

Query: 89   DMAELTCLNEASVLHNLKDRYY-SGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKR 147
            D+  L+ L+E +VLHNLK R+  S  IYTY G+  V INPY+ LPIY +++I  Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132

Query: 148  HEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKD 207
             +M PHI+A++E AY+ M +D ++QSI+ +GESGAGKT + K  ++Y A V  S     +
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---ASE 189

Query: 208  HNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
             NI    E ++L ++PI+E+ GNAKT +NDNSSRFGK+I+I FD   +I+GAN+ TYLLE
Sbjct: 190  TNI----EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLE 245

Query: 268  KSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLS-NGYIPIPGQQDKDNF 326
            KSR V QA DER +HIFYQL + AG     +L L    ++ + S  G   I G  D ++F
Sbjct: 246  KSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDF 305

Query: 327  QETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASM-PENTVAQKLCHLL 385
            ++T +A  ++G      +S+ K+++S+L  G+++ + ER+ D  S+ P++      C LL
Sbjct: 306  EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLL 365

Query: 386  GMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALD 445
            G+   +    +   ++    +   K  + +Q   A  ALAK  Y +LF W+V  INKAL 
Sbjct: 366  GVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH 425

Query: 446  RTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
             + +Q  SFIG+LDI GFE FE+NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I 
Sbjct: 426  TSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484

Query: 506  WNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQK 565
            W  IDF  D QPCIDLIE      G+L LLDEEC  PK TD+ + +KL     S   FQK
Sbjct: 485  WTLIDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK 540

Query: 566  PRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELW-KDVDR 624
            PR       F I+H+A KV+Y +D +L KN D + +    +L  S    VA+L+  D D 
Sbjct: 541  PRM--SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598

Query: 625  IVGLDQVTGMT-----ETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCI 679
            +       G +      +A      + K   +TVG  ++ SL  LM TL  T P++VRCI
Sbjct: 599  VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCI 658

Query: 680  IPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG 739
             PN EK     DP   + QLR  GVLE IRI   G+P+R  + +F  RY +L        
Sbjct: 659  KPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELA 717

Query: 740  FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRG 799
              D K  C  ++  L  DP+ ++ G++KIFFRAG +A+LE+ R  K     I  Q   RG
Sbjct: 718  NTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRG 777

Query: 800  YLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQA--- 856
            +L +    K  +   A   LQR C  +L  R  +  R       L +  R +   QA   
Sbjct: 778  WLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQR 834

Query: 857  ------------------KDEELLKVKEKQTKVEGELEE-MERKHQQLLEEKNILAE--- 894
                              +    + ++ K T ++  +   M R+H Q L +  I+ +   
Sbjct: 835  VRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAF 894

Query: 895  -QLQAETELFAEAEEMRARLAAKKQE--LEEILHDLESRVEEEEERNQILQNEKKKMQAH 951
              L+A  EL A   E R+    K+    +E  +  L+ +++E+ +  + L  +     + 
Sbjct: 895  RMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTST 954

Query: 952  IQDLEEQLDEE---------EGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002
                 E+L +E         E    +LQ E  +   ++++   E  +LED +S   +EK 
Sbjct: 955  YTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHS---REKD 1011

Query: 1003 LMEDRIAECSSQ---LAEEEEKAKNLAKIRNKQEVMISDLEERLKK----EEKTR-QELE 1054
             +  R+A+   +   L +E+E+  N    ++K E   + ++E L K    EE++R Q L 
Sbjct: 1012 ELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLV 1071

Query: 1055 KAKRKLDGETTDLQDQIA--------------ELQAQIDELKLQLAKKE-EELQGALARG 1099
            K   +L+    +L+D++               +   + D     ++  E  + + AL + 
Sbjct: 1072 KEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQV 1131

Query: 1100 DDETLHKNNA-LKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDT 1158
            ++  L K    + V  +LQ ++ EL+++    K  + + EK+++  S++++A   + +  
Sbjct: 1132 EEIGLEKAAMDMTVFLKLQKRVRELEQE---RKKLQVQLEKREQQDSKKVQAEPPQTDID 1188

Query: 1159 LDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHAT--ALEELSEQLEQAK 1216
            LD  A       KR++  +E KK   +  +  +A      Q +++  + +  S  L Q K
Sbjct: 1189 LDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLK 1248

Query: 1217 RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
                 LE  K+ +      L  ++    Q +    +    ++A+    +++        +
Sbjct: 1249 LAHEELEVRKEEVLI----LRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAI 1304

Query: 1277 ELAEKASKLQNELDNVSTLLEEAE----KKGIKFAKDAASLESQLQDTQELLQEETRQKL 1332
            E      +  ++ ++   L E+ E     +G+K  + A  LE+QLQ  Q L  EE  + L
Sbjct: 1305 EAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLK--QVARLLEAQLQ-AQSLEHEEEVEHL 1361

Query: 1333 NLSSRIRQLEEEKNSLQEQQE---------EEEEARKNLEKQVLALQSQLADTKKKVDDD 1383
                   QLE  K  + +QQ+          E +    +++++  L ++  D K+     
Sbjct: 1362 K-----AQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKE----- 1411

Query: 1384 LGTIESLEEAKKKLLKDAEALSQRLE--EKALAYDKLEKTKNRLQQELDDLTVDLDHQRQ 1441
               +E LE+ ++KL K  +   ++ +  E A A  + E+ ++ L +++     + D Q  
Sbjct: 1412 --LVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGM 1469

Query: 1442 VASNLEKKQKKFDQLLAEEK 1461
            +  + E +      L+ + K
Sbjct: 1470 LEYHKEDEALLIRNLVTDLK 1489



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 138/612 (22%), Positives = 254/612 (41%), Gaps = 89/612 (14%)

Query: 1043 LKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDE 1102
            L+ E ++ + L++    ++ +   LQ +I E   +   L  QL+         + R   E
Sbjct: 906  LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKE 965

Query: 1103 TLH------KNNALKVVRELQAQIAELQEDFESEKA-----SRNKAEKQKR--DLSEELE 1149
             +H      ++ +L++  E+++   ELQ      K      SR K E +KR  DL +E  
Sbjct: 966  LVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENA 1025

Query: 1150 ALKTELEDTLDTTAAQQELRTKREQEVAE--LKKALEEETKNHEAQIQD---MRQRHATA 1204
             LK E E  L+     Q      +  V E  +KK LEEE   ++  +++   + QR+   
Sbjct: 1026 LLKDEKEQ-LNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNL 1084

Query: 1205 LEELSEQLEQAKRFKANLEKNKQGLETDNK-------ELACEVKVLQQVKA--------- 1248
             +E++  ++Q    + N   N+  LE+D+        E+      LQQV+          
Sbjct: 1085 RDEMTI-IKQTPGHRRN-PSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMD 1142

Query: 1249 ------------ESEHKRKKLDAQVQELHAKVS-----EGDRLRVELAEKASKLQNELDN 1291
                        E E +RKKL  Q+++   + S     E  +  ++L   A    N L  
Sbjct: 1143 MTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKR 1202

Query: 1292 VSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQ 1351
                 +E E +  K   D   L   + D             + S  + QL+     L+ +
Sbjct: 1203 -----QELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVR 1257

Query: 1352 QEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEK 1411
            +EE    R  +   V A Q +LA   +  + ++    S   ++K + +         E+ 
Sbjct: 1258 KEEVLILRTQI---VSADQRRLAG--RNAEPNINARSSWPNSEKHVDQ---------EDA 1303

Query: 1412 ALAYDKLEKTKNRLQQ-----ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISAR 1466
              AY  + +T ++ +      E  +L +     +QVA  LE + +   Q L  E+ +   
Sbjct: 1304 IEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQA--QSLEHEEEVEHL 1361

Query: 1467 YAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKN 1526
             A+     EA   E + +  +  + L  + EA+ EF  Q +  R   E+L     D+ + 
Sbjct: 1362 KAQ----LEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENL-----DLKEL 1412

Query: 1527 VHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQ 1586
            V +LEK++R L++Q++    + ++LE      +  + R E+N Q    + E+D Q   E 
Sbjct: 1413 VEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEY 1472

Query: 1587 NEEKKRLLIKQV 1598
            ++E + LLI+ +
Sbjct: 1473 HKEDEALLIRNL 1484



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 139/684 (20%), Positives = 274/684 (40%), Gaps = 141/684 (20%)

Query: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
            + +KA  E K  +++A+  E H K     RL V +  K  +LQ ++D  +          
Sbjct: 895  RMLKARRELKALRIEARSAE-HLK-----RLNVGMENKVVQLQRKIDEQN---------- 938

Query: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE 1363
                K+  +L  QL  T      E          + +L++E    Q+   E+   R   E
Sbjct: 939  ----KEFKTLSEQLSVTTSTYTME----------VERLKKELVHYQQSPGEDTSLRLQEE 984

Query: 1364 KQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKN 1423
             + L  + Q A +++K+ +D  + E  ++  +K + D E      +E AL  D+ E+  N
Sbjct: 985  VESLRTELQRAHSERKILEDAHSRE--KDELRKRVADLE------QENALLKDEKEQLNN 1036

Query: 1424 R-LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKE 1482
            + L Q  D+   +   +  +   LE+++ ++  L+ E   +  RY   RD        K+
Sbjct: 1037 QILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTII---KQ 1093

Query: 1483 TKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH--------ELEKSK 1534
            T       + + +LE+   +   +     D ED +   +++G            +L+K  
Sbjct: 1094 TPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRV 1153

Query: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL 1594
            R LEQ+ ++++ QLE+ E +     D+K      +QA   Q + DL    +         
Sbjct: 1154 RELEQERKKLQVQLEKREQQ-----DSK-----KVQAEPPQTDIDLDPNAD--------- 1194

Query: 1595 IKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1654
                               LA  S K+ E+         E+ NK     + +LRK  A  
Sbjct: 1195 -------------------LAYNSLKRQEL---------ESENKKLKNDLNELRKAVADQ 1226

Query: 1655 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
                     +  S   +  Q K + ++L+  + E+L L+ ++ S+++ R         + 
Sbjct: 1227 ATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNI- 1285

Query: 1715 DEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1774
                +S       +D++  +EA     +   + E  +   LN+            + EL 
Sbjct: 1286 -NARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTE--DWGYLNE------------DGELG 1330

Query: 1775 AERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA 1834
                       A Q L++  + L+A+LQ    A   + +  +  L+A++  L+E+++++ 
Sbjct: 1331 L----------AYQGLKQVARLLEAQLQ----AQSLEHEEEVEHLKAQLEALKEEMDKQ- 1375

Query: 1835 KERAAANKLVRRTEKKLKEIFMQVEDERRHADQY--KEQMEKANARMKQLKRQLE----- 1887
             ++     L+   E ++ E  +Q E  R   +    KE +EK     ++LK+QL+     
Sbjct: 1376 -QQTFCQTLLLSPEAQV-EFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKK 1433

Query: 1888 ----EAEEEATRANASRRKLQREL 1907
                EA +   ++   R +L R++
Sbjct: 1434 AQDLEAAQALAQSERKRHELNRQV 1457



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 82/393 (20%), Positives = 153/393 (38%), Gaps = 80/393 (20%)

Query: 1450 QKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK-----EEFER 1504
            ++ F +L      I   +   + R E +A   E ++    + L   +E K      + + 
Sbjct: 877  RRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE 936

Query: 1505 QNKQLRADMEDLMSSKDDVGKNVHELEK------------SKRALEQQVEEMRTQLEELE 1552
            QNK+ +   E L  +       V  L+K            +   L+++VE +RT+L+   
Sbjct: 937  QNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAH 996

Query: 1553 DELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQR 1612
             E +  EDA  R                    E++E +KR  +  + +  A L+DE++Q 
Sbjct: 997  SERKILEDAHSR--------------------EKDELRKR--VADLEQENALLKDEKEQL 1034

Query: 1613 ALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIF 1672
               +  + K E           A N  ++ ++K             +ELEE R+    + 
Sbjct: 1035 NNQILCQSKDEF----------AQNSVKENLMK-------------KELEEERSRYQNLV 1071

Query: 1673 AQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG--------- 1723
             +  + E++  +L  E+  +++           +  E D     I+ S  G         
Sbjct: 1072 KEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQV 1131

Query: 1724 -----KSALLDEK--RRLEARIAQLEEELEEEQSNMELLNDR-FRKTTLQVDTLNAELAA 1775
                 + A +D     +L+ R+ +LE+E ++ Q  +E    +  +K   +    + +L  
Sbjct: 1132 EEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDP 1191

Query: 1776 ERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808
                A  S   RQ+LE +NK+LK  L EL  AV
Sbjct: 1192 NADLAYNS-LKRQELESENKKLKNDLNELRKAV 1223



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 105/533 (19%), Positives = 196/533 (36%), Gaps = 116/533 (21%)

Query: 1484 KALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNV----HELEKSKRALEQ 1539
            KA    +AL     + E  +R N  +   +  L    D+  K       +L  +      
Sbjct: 898  KARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTM 957

Query: 1540 QVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTR---DEQNEEKKRLLIK 1596
            +VE ++ +L   +      ED  LRL+  +++++ + +R    R   ++ +  +K  L K
Sbjct: 958  EVERLKKELVHYQQS--PGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRK 1015

Query: 1597 QVRELEAE---LEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQ 1653
            +V +LE E   L+DE++Q    +  + K E           A N  ++ ++K        
Sbjct: 1016 RVADLEQENALLKDEKEQLNNQILCQSKDEF----------AQNSVKENLMK-------- 1057

Query: 1654 MKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDEL 1713
                 +ELEE R+    +  +  + E++  +L  E+  +++           +  E D  
Sbjct: 1058 -----KELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSN 1112

Query: 1714 ADEITNSASG--------------KSALLDEK--RRLEARIAQLEEELEEEQSNMELLND 1757
               I+ S  G              + A +D     +L+ R+ +LE+E ++ Q  +E    
Sbjct: 1113 YPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQ 1172

Query: 1758 RFRKTTLQVDTLNAELAAERSAAQKSDNA-RQQLERQNKELKAKLQELEGAVKSKFKA-- 1814
            +  K  +Q +    ++  + +A    ++  RQ+LE +NK+LK  L EL  AV  +     
Sbjct: 1173 QDSKK-VQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNN 1231

Query: 1815 -------TISALEAKIGQLEEQLEQEAKE---------RAAANKLVRRTEKKLKEIFMQV 1858
                   + S L  ++    E+LE   +E          A   +L  R  +         
Sbjct: 1232 SSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSW 1291

Query: 1859 EDERRHADQ--------------------------------YKEQMEKANARMKQLKRQL 1886
             +  +H DQ                                Y+   + A     QL+ Q 
Sbjct: 1292 PNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQS 1351

Query: 1887 EEAEEEATRANASRRKLQRELD-------------DATEANEGLSREVSTLKN 1926
             E EEE     A    L+ E+D                +   G+ +E+S L N
Sbjct: 1352 LEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTN 1404



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 62/321 (19%), Positives = 134/321 (41%), Gaps = 56/321 (17%)

Query: 1702 ARRHAEQERD-----ELADEITNSASGKSALLDEKRR----------LEARIAQLEEELE 1746
            ARRH ++ RD     + A  +  +     AL  E R           +E ++ QL+ +++
Sbjct: 876  ARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKID 935

Query: 1747 EEQSNMELLNDRFRKTT----LQVDTLNAELAAERSAA---------QKSDNARQQLERQ 1793
            E+    + L+++   TT    ++V+ L  EL   + +          ++ ++ R +L+R 
Sbjct: 936  EQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRA 995

Query: 1794 NKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ-------EAKERAAANKLVRR 1846
            + E K  L++     K + +  ++ LE +   L+++ EQ       ++K+  A N +   
Sbjct: 996  HSERKI-LEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKEN 1054

Query: 1847 TEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEE-ATRANASRRKLQR 1905
              KK      ++E+ER       ++  +   R   L+ ++   ++    R N S    Q 
Sbjct: 1055 LMKK------ELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSN---QS 1105

Query: 1906 ELDDATEANEGLSREVSTLKNRLRRGGPIS----------FSSSRSGRRQLHLEGASLEL 1955
             L+  +      + E+   ++ L++   I           F   +   R+L  E   L++
Sbjct: 1106 SLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQV 1165

Query: 1956 SDDDTESKTSDVNETQPPQSE 1976
              +  E + S   + +PPQ++
Sbjct: 1166 QLEKREQQDSKKVQAEPPQTD 1186


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  582 bits (1501), Expect = e-166
 Identities = 471/1515 (31%), Positives = 743/1515 (49%), Gaps = 176/1515 (11%)

Query: 36   VWIPSERHGFEAASIKEER--GDEVMVELAENGKKAMVNKDDIQK-----MNPPKFSKVE 88
            VWIP     +++A + ++   GD+V++   E GK    + D   K      NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 89   DMAELTCLNEASVLHNLKDRYY-SGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKR 147
            D+  L+ L+E +VLHNL+ R+  S LIYTY G+  V INPY+ LPIY E+II  Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 148  HEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKD 207
             +M PHI+A++E AY+ M +D  +QSI+ +GESGAGKT + K  ++Y A V+ S      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188

Query: 208  HNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
                  +E ++L +NPI+ES GNAKT +NDNSSRFGK+I I FD    I+GAN+ TYLLE
Sbjct: 189  ---EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245

Query: 268  KSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIP-IPGQQDKDNF 326
            KSR V QA++ER +HIFYQL + A       L L   +N+ +   G  P I G  D    
Sbjct: 246  KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305

Query: 327  QETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASM-PENTVAQKLCHLL 385
              T +A  ++G S    + + ++++ +L  GN+ F   R+ D  ++ P++      C L+
Sbjct: 306  AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364

Query: 386  GMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALD 445
            G++  E    +   ++    +   K  +K QA  A +ALAK  Y +LF W+V  +N+AL 
Sbjct: 365  GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424

Query: 446  RTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
               +Q  SFIG+LDI GFE FE+NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I 
Sbjct: 425  SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483

Query: 506  WNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQ-GSHSKFQ 564
            W  IDF  D QPCI+LIE   +  G+L LLDEEC  PK TD T+ +KL        + F+
Sbjct: 484  WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539

Query: 565  KPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDR 624
            KPR L +KA F I H+A KV+Y+ + +L KN D + +    +L  S  + + EL++D ++
Sbjct: 540  KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597

Query: 625  IVGLDQVT--GMTETAFGSAYKTK-------KGMFRTVGQLYKESLTKLMATLRNTNPNF 675
             +     T  G T      A  TK       K   +TVG  ++ SL  LM TL  T P++
Sbjct: 598  AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657

Query: 676  VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA 735
            VRCI PN  K     D    + QLR  GVLE IRI   GFP+R  +QEF  RY +L    
Sbjct: 658  VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716

Query: 736  IPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQA 795
                  D KQ C+ ++  L LD + Y+ G++KIFFRAG +A+LE+ R  K+    I  Q 
Sbjct: 717  -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775

Query: 796  VCRGYLARKAFAKKQQQLSAL-------------KVLQRNCAAYLKLRHWQWWRVFTKVK 842
              RG+L RK + + ++    +             K L+R  AA +  ++W+         
Sbjct: 776  TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWR--------- 826

Query: 843  PLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAE--- 899
              + V R+  +++     +L+   +         ++ R+H+ ++ +K +     +     
Sbjct: 827  --MYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKR 884

Query: 900  ------------TELFAEAEEMRARLAAKKQELEEILH--------DLESRVEEEEERNQ 939
                          + A+ E  + ++ A+  E  + LH         L+ +V+E+ +  +
Sbjct: 885  SMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYK 944

Query: 940  ILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIK 999
             L  +   ++       E+L  +    Q  + E   A  ++  ++EEI  L     +   
Sbjct: 945  CLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRS 1004

Query: 1000 EKKLME---DRIAECSSQLA----------EEEEKAKNLAKIRNKQEVMISDLEERLKKE 1046
            EKK +E   DR  + + QL           ++E++A N   ++  +E M   +E++L +E
Sbjct: 1005 EKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKE-MTETMEKKLVEE 1063

Query: 1047 EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHK 1106
             K + EL+    +L     +L ++ + L+ + D+LK ++       +    R D  + H 
Sbjct: 1064 TK-QLELDLNDERL--RYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTD--STHS 1118

Query: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166
            +N  + +    ++IAE+ ED  S               +EE    K  L+ +L       
Sbjct: 1119 SNESEYI--FSSEIAEM-EDIPSR--------------TEEPSEKKVPLDMSLFLKL--- 1158

Query: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
                KR  E+ + K+ +++E    E Q+       + A EE   Q+  A+    +L+  +
Sbjct: 1159 ---QKRVTELEQEKQVMQDELDRKEEQV-----LRSKAKEEERPQIRGAELEYESLK--R 1208

Query: 1227 QGLETDNKELACEVKVLQQVKAESEHKR-------------KKLDAQVQELHAKVSEGDR 1273
            Q LE++NK+L  E+  L++  +E                  ++L +  +EL  +  E   
Sbjct: 1209 QELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLI 1268

Query: 1274 LRVELAEKASKLQ-----NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEET 1328
            LR +L  +   +Q     N + + + LLE+ +K               ++D  E+ Q   
Sbjct: 1269 LRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQK---------------MKDKGEIAQAYI 1313

Query: 1329 RQK-LNLSSRIRQLE-EEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1386
              K  N SS +   E  E   L    E  ++A + LE Q   LQSQ    + + +   G 
Sbjct: 1314 GLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ---LQSQKRSHENEAEALRGE 1370

Query: 1387 IESLEEAKKKLLKDAEALSQRLE--EKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVAS 1444
            I+SL+E      +  + L+Q L+   +A     L+    RL  E  DL   L+ Q +   
Sbjct: 1371 IQSLKEENN---RQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVR 1427

Query: 1445 NLEKKQKKFDQLLAE 1459
             L+K+ K F + + E
Sbjct: 1428 KLKKQLKVFAKKIGE 1442



 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 131/620 (21%), Positives = 264/620 (42%), Gaps = 93/620 (15%)

Query: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
            +++ A+ E K+ K++A+  E + K      L + +  K  +LQ ++D  +          
Sbjct: 897  RRMMAKRELKKLKIEARSVERYKK------LHIGMENKIMQLQRKVDEQN---------- 940

Query: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE 1363
                KD   L  +L + + +   ET             E+ ++ L+  Q  EEEA K   
Sbjct: 941  ----KDYKCLVEKLTNLEGIYNSET-------------EKLRSDLERLQLSEEEA-KVAT 982

Query: 1364 KQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRL-EEKALAYDKLEKTK 1422
             +VL+LQ ++A  +K ++      + +EE   +  ++ E L   L EE  L   + E   
Sbjct: 983  GRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALN 1042

Query: 1423 NRLQQELDDLTVDLDHQ-----RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAE 1477
            +R+ Q+  ++T  ++ +     +Q+  +L  ++ ++  LL E   +  RY + ++     
Sbjct: 1043 HRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLM 1102

Query: 1478 AREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK-RA 1536
                +           ++  +  E E       A+MED+ S  ++  +    L+ S    
Sbjct: 1103 VHVPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK 1157

Query: 1537 LEQQVEEMRTQLEELEDELQATEDAKLRL----EVNMQAMKAQFERDLQTRDEQNEEKKR 1592
            L+++V E+  + + ++DEL   E+  LR     E   Q   A+ E +   R E   E K+
Sbjct: 1158 LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKK 1217

Query: 1593 LLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652
            L   ++ EL   L ++      A  +     + ++ L +  E  +  ++EV+    +L +
Sbjct: 1218 LK-NELNELRKALSEKSAPEVTAPGAPA-YRVLMEQLTSVSEELDVRKEEVLILRSQLVS 1275

Query: 1653 QMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDE 1712
            Q +  Q + ++   +   I     E  +K+K  + EI Q    L  + R+      E +E
Sbjct: 1276 QKEAIQPKDDKNTMTDSTILL---EDVQKMKD-KGEIAQAYIGLKETNRSSALDYHELNE 1331

Query: 1713 LADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAE 1772
                      G+  L+ E  +   R+  LE +L+ ++ + E           + + L  E
Sbjct: 1332 ---------DGELWLVYEGLKQANRL--LESQLQSQKRSHEN----------EAEALRGE 1370

Query: 1773 LAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ 1832
            +     + ++ +N +QQL  QN +L       E  +++  +  I+ L  +   L EQLE+
Sbjct: 1371 I----QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEK 1421

Query: 1833 EAKERAAANKLVRRTEKKLK 1852
            +       +K VR+ +K+LK
Sbjct: 1422 Q-------DKTVRKLKKQLK 1434



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 145/626 (23%), Positives = 264/626 (42%), Gaps = 98/626 (15%)

Query: 1197 MRQRHATALEELSEQLEQAKRFKANLEKN----KQGLETDNKELACEVKVLQQVK----A 1248
            M +R    L+  +  +E+ K+    +E      ++ ++  NK+  C V+ L  ++    +
Sbjct: 900  MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959

Query: 1249 ESEHKRKKLDA-QVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
            E+E  R  L+  Q+ E  AKV+ G  L   L E+ +KL+ +L+        +EKK I+  
Sbjct: 960  ETEKLRSDLERLQLSEEEAKVATGRVL--SLQEEIAKLRKDLEQT-----RSEKKCIEEH 1012

Query: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
             D        Q+T++L+        NL        +E+N+L +Q++E             
Sbjct: 1013 ADRYK-----QETEQLVS-------NL--------KEENTLLKQEKE------------- 1039

Query: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ 1427
            AL  ++    K         E  E  +KKL+++ + L   L ++ L Y  L    +RL++
Sbjct: 1040 ALNHRIVQQAK---------EMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEE 1090

Query: 1428 ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD---RAEAEAREKETK 1484
              DDL  ++     V     K+          E   S+  AE  D   R E  + +K   
Sbjct: 1091 RYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPL 1150

Query: 1485 ALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEM 1544
             +SL   L++ +   E    Q KQ+   M+D +  K++         K+K     Q+   
Sbjct: 1151 DMSLFLKLQKRVTELE----QEKQV---MQDELDRKEEQVLR----SKAKEEERPQIRGA 1199

Query: 1545 RTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAE 1604
              + E L+ +   +E+ KL+ E+N +  KA  E+             R+L++Q+  +  E
Sbjct: 1200 ELEYESLKRQELESENKKLKNELN-ELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEE 1258

Query: 1605 LEDERKQRALAVASK---KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL 1661
            L D RK+  L + S+   +K  I  KD +  +  +    ++V K   K +   + Y    
Sbjct: 1259 L-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEI-AQAYIGLK 1316

Query: 1662 EEARASRDEIFAQSKESEKKL--KSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
            E  R+S  +    +++ E  L  + L+     L+ +L S +R+    E E + L  EI  
Sbjct: 1317 ETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSH---ENEAEALRGEI-- 1371

Query: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779
                  +L +E  R +  +AQ  +   E +    L ++  R T   +D +          
Sbjct: 1372 -----QSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLM--------EQ 1418

Query: 1780 AQKSDNARQQLERQNKELKAKLQELE 1805
             +K D   ++L++Q K    K+ ELE
Sbjct: 1419 LEKQDKTVRKLKKQLKVFAKKIGELE 1444



 Score = 65.1 bits (157), Expect = 7e-10
 Identities = 95/464 (20%), Positives = 198/464 (42%), Gaps = 53/464 (11%)

Query: 1475 EAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1534
            + + + K+ K L     +E+    +  +  + ++LR+D+E L  S+++       +    
Sbjct: 935  KVDEQNKDYKCL-----VEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV---- 985

Query: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL 1594
             +L++++ ++R  LE+   E +  E+   R +   + + +  + +     ++ E     +
Sbjct: 986  LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045

Query: 1595 IKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1654
            ++Q +E+   +E +       V   K++E+DL D   + +        ++ +  +L+ + 
Sbjct: 1046 VQQAKEMTETMEKK------LVEETKQLELDLNDERLRYQ-------NLLNEFSRLEERY 1092

Query: 1655 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
             D + E+         +    K   K+  S  +      E + SSE A       R    
Sbjct: 1093 DDLKEEMTL-------MVHVPKPGHKRTDSTHSS--NESEYIFSSEIAEMEDIPSR---- 1139

Query: 1715 DEITNSASGKSALLDEKR--RLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAE 1772
               T   S K   LD     +L+ R+ +LE+E +  Q  +    DR  +  L+      E
Sbjct: 1140 ---TEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDEL----DRKEEQVLRSKAKEEE 1192

Query: 1773 LAAERSAAQKSDNA-RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ-LEEQL 1830
                R A  + ++  RQ+LE +NK+LK +L EL  A+  K    ++A  A   + L EQL
Sbjct: 1193 RPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQL 1252

Query: 1831 EQEAKERAAANK--LVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEE 1888
               ++E     +  L+ R++   ++  +Q +D++         +E    +MK  K ++ +
Sbjct: 1253 TSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ-KMKD-KGEIAQ 1310

Query: 1889 AEEEATRANASRRKLQRELDDATE---ANEGLSREVSTLKNRLR 1929
            A       N S      EL++  E     EGL +    L+++L+
Sbjct: 1311 AYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQ 1354



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 18/121 (14%)

Query: 864  VKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEI 923
            +K+    +E +L+  +R H+         AE L+ E +   E    + +L A+  +L   
Sbjct: 1342 LKQANRLLESQLQSQKRSHENE-------AEALRGEIQSLKEENNRQQQLLAQNLQLPP- 1393

Query: 924  LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKM 983
                E+R+E        LQ+E  ++     DL EQL++++   +KL+ +      KI ++
Sbjct: 1394 ----EARIEAS------LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGEL 1443

Query: 984  E 984
            E
Sbjct: 1444 E 1444


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score =  582 bits (1500), Expect = e-165
 Identities = 437/1686 (25%), Positives = 825/1686 (48%), Gaps = 167/1686 (9%)

Query: 25   ATQADWTAKKLVWIPSERHGFEAAS-IKEERGD----EVMVELAENGKKAMVNKDDIQKM 79
            A +  W   + VW+   R GF  AS +K E  +    +V V+L  +G    V++DD++K 
Sbjct: 341  AAEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKA 399

Query: 80   NPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENII 139
            N P   ++ED+A L  LNE+SVLH L+ RY + L++TY+G   +V+ P     +YSE ++
Sbjct: 400  NAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVM 459

Query: 140  EMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVA 199
             M++G +R +M PHIYA++++AYR ML  R+DQSI+  G SG+GKT + + ++QYLA +A
Sbjct: 460  HMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIA 519

Query: 200  SSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 259
                G K  ++    + Q L    +LE+FGN+ T+ N N++RF + + ++FD  G +  A
Sbjct: 520  GI-SGNKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASA 573

Query: 260  NIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPG 319
            +I+T LLEK R  R+   E TF++FY LL+     L+++L L           G +P+  
Sbjct: 574  SIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVF--GIVPLAK 631

Query: 320  QQDKDN----FQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKER-NTDQASMPE 374
             ++K      F +   AM ++G S +E  +   +++++   G     KE     +     
Sbjct: 632  PEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFAR 691

Query: 375  NTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQ----------------AD 418
            +  AQK  +LLG ++ E + AI   + K G   +Q++ +  Q                A 
Sbjct: 692  HEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSAL 749

Query: 419  FAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELN------SFE 472
              +E +A   Y  LF  LV  +N+AL  ++    S + I+D  GF+  E        SFE
Sbjct: 750  ECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFE 808

Query: 473  QLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPP--- 529
            +LC NYT ++LQ+LF+   F+ E E Y+ E IE  F D        +  +++ ++     
Sbjct: 809  ELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVR 868

Query: 530  ---------GVLALLDEECWFPKATDKTFVEKLVQEQGSHS---KFQKPRQLKDKADFCI 577
                     G+L LL+EE   P A++ T +E+L    G      K Q P     K    +
Sbjct: 869  SLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFL 928

Query: 578  I---HYAGKVDYKADEWL-MKNMDPLNDNVATLLHQSSDRFVAELWKD--------VDRI 625
            +   H    V+Y    WL     +P   N   LL  S  + ++ L+             I
Sbjct: 929  LGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSI 988

Query: 626  VGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLT--------KLMATLRNTNPNFVR 677
             GL+   G ++ A   A   +K     +  + K+SL          L+ T++ +  +FV 
Sbjct: 989  AGLE---GGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVH 1045

Query: 678  CIIPNHEKRAGK-----------------------------LDPHLVLDQLRCNGVLEGI 708
            C +P  E  AG+                             LD  L+  QLR + +L+ +
Sbjct: 1046 CFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAM 1105

Query: 709  RICRQGFPNRIVFQEFRQRYEILTPNAIPKG-----FMDGKQACERMIRALELDPNLYRI 763
            R+ RQG+P+ +VF EFR+R+++L P+   K       +D ++A E ++  L+L+ +   +
Sbjct: 1106 RMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCM 1165

Query: 764  GQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNC 823
            G S++FFRAG LA LEE+RD + +  +  FQA CRGYLAR+ F K++ Q  A++ +Q+N 
Sbjct: 1166 GLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNI 1225

Query: 824  AAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQ 883
                 ++ W WW++FT V+PL++V   EE+++ KDEE+ +++ K  K E E  E+     
Sbjct: 1226 KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSD 1285

Query: 884  QLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQN 943
            +L    + L  +L  E      A ++     A++   E+ + +L+++ +  +++ ++++ 
Sbjct: 1286 RLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEM 1345

Query: 944  EKKKMQ-AHIQDLEEQLDEEE-GARQKLQLEKVTAEAKI--KKMEEEILLLEDQNSKFIK 999
            E  + +     ++  ++D+++ G   +L+ E+   E     K++++E    ED+     +
Sbjct: 1346 EVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLEVEQQ 1402

Query: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059
             K+ +E R+ +  +   E +   + L K   +    + D +  L+ ++    ELEK +R+
Sbjct: 1403 NKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRR 1462

Query: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNA-----LKVVR 1114
             D E +      A  +AQ ++L+ +  ++E+++  A A    + L + +       + V 
Sbjct: 1463 FDSELSQ-----AHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV 1517

Query: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174
             L+A++ ++      ++AS  K +KQ RDL  +++  + EL++   T    ++ + + E 
Sbjct: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577

Query: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
            E+  +++   +E ++ + ++++ RQ     L+++  QLE+    K  + + K+ LE    
Sbjct: 1578 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637

Query: 1235 ELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVST 1294
             L+       QV        K+L   ++   A +++  +L ++  + ++  + E+  +  
Sbjct: 1638 TLS------DQVNRRDFESEKRLRKDLKRTKALLADA-QLMLDHLKNSAPSKREIAQLKN 1690

Query: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
             LEE+E       K   ++E +++D    + +  + K  L  ++ +L+ EKN +Q + EE
Sbjct: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750

Query: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
            ++E    L K+  A  +Q +    +++D    +E   + K++L +  +AL  ++E   L 
Sbjct: 1751 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVE--FLE 1808

Query: 1415 YDKLEKT-KNRLQQELDDLTVDLDHQR-----------QVASNLEKKQKKFDQLLAEEKS 1462
               ++K+  +R + ++ +L   L+ +R           ++  N+EK  ++ DQ +A E  
Sbjct: 1809 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN- 1867

Query: 1463 ISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDD 1522
               R  E+  R + + R+ + +   LAR   EA   K E E   + L A  + L +    
Sbjct: 1868 ---REKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKL 1924

Query: 1523 VGKNVHELEKS---------KRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK 1573
              K + +L+ +            L   +++M T+ ++ +++L+   D    LE  +  +K
Sbjct: 1925 AFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVK 1984

Query: 1574 AQFERD 1579
            +   ++
Sbjct: 1985 SWLSKN 1990



 Score =  228 bits (580), Expect = 6e-59
 Identities = 174/736 (23%), Positives = 373/736 (50%), Gaps = 58/736 (7%)

Query: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
            N++KNK   +    +L   V+ L +V+   E  R K D ++Q+L +K+ + ++ R EL  
Sbjct: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK-DEEIQQLRSKLEKAEKERNELRL 1282

Query: 1281 KASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340
             + +L++ +  +++ L +    G              +   +LL  ET ++L     +++
Sbjct: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328

Query: 1341 LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLG----------TIESL 1390
            L+ + ++L++Q E  E   + +E +++    + A+   +VDDD             +  +
Sbjct: 1329 LQTQYDALKKQMEVME--MEVMEARLI----RAAEINGEVDDDDAGGEWRLKYERAVREV 1382

Query: 1391 EEAKKKLLKDAE-----------ALSQRL-------EEKALAYDKLEKTKNRLQQELDDL 1432
            +  KK+L ++ E            L +RL       EE   A  +L+K   RL  EL D 
Sbjct: 1383 DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1442

Query: 1433 TVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARAL 1492
             + L+ Q+     LEKKQ++FD  L++    + R   +R++ + E      +A SL + L
Sbjct: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQL 1502

Query: 1493 EEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELE 1552
            EE       F ++   L A+++D+ S +     ++ +++K  R LE +V++   +L+E  
Sbjct: 1503 EEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQA 1562

Query: 1553 DELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQR 1612
              +Q  E AKLRLE+ M+ M+    +++++RDE+ EE ++   K+++++E +LE+E + +
Sbjct: 1563 GTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDK 1622

Query: 1613 ALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIF 1672
               +  K+++E  L  L  Q+   N+   E  K+LRK    +K  +  L +A+   D + 
Sbjct: 1623 QKVLREKRELEGKLATLSDQV---NRRDFESEKRLRK---DLKRTKALLADAQLMLDHL- 1675

Query: 1673 AQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKR 1732
              S  S++++  L+ ++ + +   A++ +AR+  E E ++L  +I + A  K+AL ++  
Sbjct: 1676 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735

Query: 1733 RLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLER 1792
            RL+    +++  LEE+Q +M  L  + +    Q     A++   ++  ++++  +Q+L+ 
Sbjct: 1736 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1795

Query: 1793 QNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLK 1852
            + + L+++++ LE ++    K+ +S  EAKI +LE +LE E  +      L  R ++ ++
Sbjct: 1796 KLQALQSQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1853

Query: 1853 EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATE 1912
            ++  + +      ++ KEQ ++   +++  K ++ E   +   A+  + +L+ +L+    
Sbjct: 1854 KLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1913

Query: 1913 ANEGLSREVSTLKNRL 1928
            AN+ L  ++     R+
Sbjct: 1914 ANQSLQADLKLAFKRI 1929



 Score =  181 bits (458), Expect = 8e-45
 Identities = 180/849 (21%), Positives = 388/849 (45%), Gaps = 90/849 (10%)

Query: 1000 EKKLMEDRIAECSSQLAEEEEKAKN------LAKIRNKQEVMISDLEERLKKEEKTRQEL 1053
            +K+ ++D    C  +  ++ +  K+         +R   EV +S  EE+++ +++  Q+L
Sbjct: 1209 KKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS--EEQIRNKDEEIQQL 1266

Query: 1054 EKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVV 1113
                 K + E  +L+     L+++I EL  +L  +    + A    D ET  +  A K +
Sbjct: 1267 RSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326

Query: 1114 RELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKRE 1173
            +ELQ Q   L++  E            + ++ E       E+   +D   A  E R K E
Sbjct: 1327 KELQTQYDALKKQMEV----------MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376

Query: 1174 QEVAEL---KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLE 1230
            + V E+   KK L++E ++     Q  +++    L +L    E+++R    L+K  Q L 
Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436

Query: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290
             + ++    ++  Q    E E K+++ D+++ + H +       R +L  +   L  E  
Sbjct: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496

Query: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350
            ++   LEE +     F +   SLE++LQD                            +  
Sbjct: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQD----------------------------ISS 1528

Query: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
            Q+ ++E +   ++KQ+  L++++ D ++++D+  GTI+ LE+AK +L  + E + Q   +
Sbjct: 1529 QESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSK 1588

Query: 1411 KALAYDK-LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAE-EKSISARYA 1468
            +  + D+ +E+ +   Q++L  + V L+ + +    + +++++ +  LA     ++ R  
Sbjct: 1589 EMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDF 1648

Query: 1469 EERDRAEAEAREKETKALSL-ARALEEALEAKEEFERQNKQLRADMED------------ 1515
            E   R   +   K TKAL   A+ + + L+     +R+  QL+  +E+            
Sbjct: 1649 ESEKRLRKDL--KRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKAR 1706

Query: 1516 --LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK 1573
              +    +D+   + ++ K+K ALE+Q+  ++ +  E+++ L+  ++    L    +A  
Sbjct: 1707 KAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAV 1766

Query: 1574 AQFERDL------QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627
            AQ  RDL      Q + E+  ++K+ L ++++ L++++E   +Q  +  +   + E  ++
Sbjct: 1767 AQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEF-LEQSMVDKSLVSRQEAKIR 1825

Query: 1628 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1687
            +LE ++E         +K+L  L +++K+   +L E R  R  I A+++E E+  K L+ 
Sbjct: 1826 ELETRLEFERTQ----VKRLESLASRLKENMEKLTEERDQR--IAAENREKEQN-KRLQR 1878

Query: 1688 EILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEE 1747
            ++   +EE+    R    A +++ EL  ++ +  +   +L  + +    RI  L+  +E+
Sbjct: 1879 QLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED 1938

Query: 1748 E---QSNMELLN---DRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKL 1801
            E     N +L+N   D   K   + + L  +   +     + D  +  L +     KA  
Sbjct: 1939 EMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLSKNKGPSKAAS 1998

Query: 1802 QELEGAVKS 1810
               +G++KS
Sbjct: 1999 D--DGSLKS 2005



 Score =  115 bits (287), Expect = 6e-25
 Identities = 131/601 (21%), Positives = 264/601 (43%), Gaps = 94/601 (15%)

Query: 1385 GTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVAS 1444
            GT+  LEE + +       L Q      LA    +K K      + DL +     R V  
Sbjct: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRK------IQDLAI-----RCVQK 1223

Query: 1445 NLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFER 1504
            N+ KK K        +   + R   E   +E + R K+ +   L   LE+A + + E   
Sbjct: 1224 NI-KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRL 1282

Query: 1505 QNKQLRADMEDLMSSKDD---VGKNVHELEKSKRA----LEQQVEEMRTQLEELEDELQA 1557
             + +L + + +L S   D    G++  +L  ++ A     E++++E++TQ + L+ +++ 
Sbjct: 1283 NSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEV 1342

Query: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE--------KKRLLIKQV----RELEAEL 1605
             E         M+ M+A+  R  +   E +++        K    +++V    + L+ E 
Sbjct: 1343 ME---------MEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF 1393

Query: 1606 EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665
            ED+ +   +   +K+++E  L DL+A  E + +A  ++ K+ ++L A+++D +  LE  +
Sbjct: 1394 EDKLE---VEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQ 1450

Query: 1666 ASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERD-------------- 1711
                E+       EKK +  ++E+ Q  EE    +  R   ++E+D              
Sbjct: 1451 VRNHEL-------EKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLE 1503

Query: 1712 ------------------ELADEITNSASGKSALLDEKRRL---EARIAQLEEELEEEQS 1750
                              EL D  +  +  +++L   K++L   EA++   EEEL+E+  
Sbjct: 1504 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAG 1563

Query: 1751 NMELLNDRFRKTTLQVDTLNAELAAE-RSAAQKSDNARQQLERQNKELKAKLQELEGAVK 1809
             +++L     +  ++++ +    + E  S  ++ + ARQ  +++ K+++ +L+E E   K
Sbjct: 1564 TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDK 1622

Query: 1810 SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYK 1869
             K       LE K+  L +Q+ +   E        +R  K LK     + D +   D  K
Sbjct: 1623 QKVLREKRELEGKLATLSDQVNRRDFESE------KRLRKDLKRTKALLADAQLMLDHLK 1676

Query: 1870 EQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
                 +   + QLK QLEE+E     A  +R+ ++ E++D     + +++  + L+ +L 
Sbjct: 1677 NSAP-SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735

Query: 1930 R 1930
            R
Sbjct: 1736 R 1736


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score =  581 bits (1497), Expect = e-165
 Identities = 444/1722 (25%), Positives = 839/1722 (48%), Gaps = 170/1722 (9%)

Query: 25   ATQADWTAKKLVWIPSERHGFEAAS-IKEERGD----EVMVELAENGKKAMVNKDDIQKM 79
            A +  W   + VW+   R GF  AS +K E  +    +V V+L  +G    V++DD++K 
Sbjct: 341  AAEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKA 399

Query: 80   NPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENII 139
            N P   ++ED+A L  LNE+SVLH L+ RY + L++TY+G   +V+ P     +YSE ++
Sbjct: 400  NAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVM 459

Query: 140  EMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVA 199
             M++G +R +M PHIYA++++AYR ML  R+DQSI+  G SG+GKT + + ++QYLA +A
Sbjct: 460  HMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIA 519

Query: 200  SSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 259
                G K  ++    + Q L    +LE+FGN+ T+ N N++RF + + ++FD  G +  A
Sbjct: 520  GI-SGNKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASA 573

Query: 260  NIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPG 319
            +I+T LLEK R  R+   E TF++FY LL+     L+++L L           G +P+  
Sbjct: 574  SIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVF--GIVPLAK 631

Query: 320  QQDKDN----FQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKER-NTDQASMPE 374
             ++K      F +   AM ++G S +E  +   +++++   G     KE     +     
Sbjct: 632  PEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFAR 691

Query: 375  NTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQ----------------AD 418
            +  AQK  +LLG ++ E + AI   + K G   +Q++ +  Q                A 
Sbjct: 692  HEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSAL 749

Query: 419  FAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELN------SFE 472
              +E +A   Y  LF  LV  +N+AL  ++    S + I+D  GF+  E        SFE
Sbjct: 750  ECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFE 808

Query: 473  QLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPP--- 529
            +LC NYT ++LQ+LF+   F+ E E Y+ E IE  F D        +  +++ ++     
Sbjct: 809  ELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVR 868

Query: 530  ---------GVLALLDEECWFPKATDKTFVEKLVQEQGSHS---KFQKPRQLKDKADFCI 577
                     G+L LL+EE   P A++ T +E+L    G      K Q P     K    +
Sbjct: 869  SLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFL 928

Query: 578  I---HYAGKVDYKADEWL-MKNMDPLNDNVATLLHQSSDRFVAELWKD--------VDRI 625
            +   H    V+Y    WL     +P   N   LL  S  + ++ L+             I
Sbjct: 929  LGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSI 988

Query: 626  VGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLT--------KLMATLRNTNPNFVR 677
             GL+   G ++ A   A   +K     +  + K+SL          L+ T++ +  +FV 
Sbjct: 989  AGLE---GGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVH 1045

Query: 678  CIIPNHEKRAGK-----------------------------LDPHLVLDQLRCNGVLEGI 708
            C +P  E  AG+                             LD  L+  QLR + +L+ +
Sbjct: 1046 CFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAM 1105

Query: 709  RICRQGFPNRIVFQEFRQRYEILTPNAIPKG-----FMDGKQACERMIRALELDPNLYRI 763
            R+ RQG+P+ +VF EFR+R+++L P+   K       +D ++A E ++  L+L+ +   +
Sbjct: 1106 RMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCM 1165

Query: 764  GQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNC 823
            G S++FFRAG LA LEE+RD + +  +  FQA CRGYLAR+ F K++ Q  A++ +Q+N 
Sbjct: 1166 GLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNI 1225

Query: 824  AAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQ 883
                 ++ W WW++FT V+PL++V   EE+++ KDEE+ +++ K  K E E  E+     
Sbjct: 1226 KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSD 1285

Query: 884  QLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQN 943
            +L    + L  +L  E      A ++     A++   E+ + +L+++ +  +++ ++++ 
Sbjct: 1286 RLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEM 1345

Query: 944  EKKKMQ-AHIQDLEEQLDEEE-GARQKLQLEKVTAEAKI--KKMEEEILLLEDQNSKFIK 999
            E  + +     ++  ++D+++ G   +L+ E+   E     K++++E    ED+     +
Sbjct: 1346 EVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLEVEQQ 1402

Query: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059
             K+ +E R+ +  +   E +   + L K   +    + D +  L+ ++    ELEK +R+
Sbjct: 1403 NKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRR 1462

Query: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNA-----LKVVR 1114
             D E +      A  +AQ ++L+ +  ++E+++  A A    + L + +       + V 
Sbjct: 1463 FDSELSQ-----AHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV 1517

Query: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174
             L+A++ ++      ++AS  K +KQ RDL  +++  + EL++   T    ++ + + E 
Sbjct: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577

Query: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
            E+  +++   +E ++ + ++++ RQ     L+++  QLE+    K  + + K+ LE    
Sbjct: 1578 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637

Query: 1235 ELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVST 1294
             L+       QV        K+L   ++   A +++  +L ++  + ++  + E+  +  
Sbjct: 1638 TLS------DQVNRRDFESEKRLRKDLKRTKALLADA-QLMLDHLKNSAPSKREIAQLKN 1690

Query: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
             LEE+E       K   ++E +++D    + +  + K  L  ++ +L+ EKN +Q + EE
Sbjct: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750

Query: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
            ++E    L K+  A  +Q +    +++D    +E   + K++L +  +AL  ++E   L 
Sbjct: 1751 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVE--FLE 1808

Query: 1415 YDKLEKT-KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD- 1472
               ++K+  +R + ++ +L   L+ +R        + K+ + L +  K    +  EERD 
Sbjct: 1809 QSMVDKSLVSRQEAKIRELETRLEFER-------TQVKRLESLASRLKENMEKLTEERDQ 1861

Query: 1473 RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532
            R  AE REK               E  +  +RQ +  + +M +L   + +  +  HELE 
Sbjct: 1862 RIAAENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM 1906

Query: 1533 SKRALEQQVEEMRTQLE---ELEDELQATEDAKLRLEVNMQAMKAQFERDLQTR-DEQNE 1588
               +LE   + ++  L+   +   +LQA  + ++  + N   + ++ + D+ +  +++ +
Sbjct: 1907 DLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVD 1966

Query: 1589 EKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE 1630
              K  L K     +A  +D   + +   +  K +  D  D E
Sbjct: 1967 GVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDE 2008



 Score =  228 bits (580), Expect = 6e-59
 Identities = 174/736 (23%), Positives = 373/736 (50%), Gaps = 58/736 (7%)

Query: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
            N++KNK   +    +L   V+ L +V+   E  R K D ++Q+L +K+ + ++ R EL  
Sbjct: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK-DEEIQQLRSKLEKAEKERNELRL 1282

Query: 1281 KASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340
             + +L++ +  +++ L +    G              +   +LL  ET ++L     +++
Sbjct: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328

Query: 1341 LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLG----------TIESL 1390
            L+ + ++L++Q E  E   + +E +++    + A+   +VDDD             +  +
Sbjct: 1329 LQTQYDALKKQMEVME--MEVMEARLI----RAAEINGEVDDDDAGGEWRLKYERAVREV 1382

Query: 1391 EEAKKKLLKDAE-----------ALSQRL-------EEKALAYDKLEKTKNRLQQELDDL 1432
            +  KK+L ++ E            L +RL       EE   A  +L+K   RL  EL D 
Sbjct: 1383 DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1442

Query: 1433 TVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARAL 1492
             + L+ Q+     LEKKQ++FD  L++    + R   +R++ + E      +A SL + L
Sbjct: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQL 1502

Query: 1493 EEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELE 1552
            EE       F ++   L A+++D+ S +     ++ +++K  R LE +V++   +L+E  
Sbjct: 1503 EEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQA 1562

Query: 1553 DELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQR 1612
              +Q  E AKLRLE+ M+ M+    +++++RDE+ EE ++   K+++++E +LE+E + +
Sbjct: 1563 GTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDK 1622

Query: 1613 ALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIF 1672
               +  K+++E  L  L  Q+   N+   E  K+LRK    +K  +  L +A+   D + 
Sbjct: 1623 QKVLREKRELEGKLATLSDQV---NRRDFESEKRLRK---DLKRTKALLADAQLMLDHL- 1675

Query: 1673 AQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKR 1732
              S  S++++  L+ ++ + +   A++ +AR+  E E ++L  +I + A  K+AL ++  
Sbjct: 1676 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735

Query: 1733 RLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLER 1792
            RL+    +++  LEE+Q +M  L  + +    Q     A++   ++  ++++  +Q+L+ 
Sbjct: 1736 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1795

Query: 1793 QNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLK 1852
            + + L+++++ LE ++    K+ +S  EAKI +LE +LE E  +      L  R ++ ++
Sbjct: 1796 KLQALQSQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1853

Query: 1853 EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATE 1912
            ++  + +      ++ KEQ ++   +++  K ++ E   +   A+  + +L+ +L+    
Sbjct: 1854 KLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1913

Query: 1913 ANEGLSREVSTLKNRL 1928
            AN+ L  ++     R+
Sbjct: 1914 ANQSLQADLKLAFKRI 1929



 Score =  177 bits (450), Expect = 7e-44
 Identities = 170/792 (21%), Positives = 368/792 (46%), Gaps = 85/792 (10%)

Query: 1000 EKKLMEDRIAECSSQLAEEEEKAKN------LAKIRNKQEVMISDLEERLKKEEKTRQEL 1053
            +K+ ++D    C  +  ++ +  K+         +R   EV +S  EE+++ +++  Q+L
Sbjct: 1209 KKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS--EEQIRNKDEEIQQL 1266

Query: 1054 EKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVV 1113
                 K + E  +L+     L+++I EL  +L  +    + A    D ET  +  A K +
Sbjct: 1267 RSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326

Query: 1114 RELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKRE 1173
            +ELQ Q   L++  E            + ++ E       E+   +D   A  E R K E
Sbjct: 1327 KELQTQYDALKKQMEV----------MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376

Query: 1174 QEVAEL---KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLE 1230
            + V E+   KK L++E ++     Q  +++    L +L    E+++R    L+K  Q L 
Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436

Query: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290
             + ++    ++  Q    E E K+++ D+++ + H +       R +L  +   L  E  
Sbjct: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496

Query: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350
            ++   LEE +     F +   SLE++LQD                            +  
Sbjct: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQD----------------------------ISS 1528

Query: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
            Q+ ++E +   ++KQ+  L++++ D ++++D+  GTI+ LE+AK +L  + E + Q   +
Sbjct: 1529 QESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSK 1588

Query: 1411 KALAYDK-LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAE-EKSISARYA 1468
            +  + D+ +E+ +   Q++L  + V L+ + +    + +++++ +  LA     ++ R  
Sbjct: 1589 EMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDF 1648

Query: 1469 EERDRAEAEAREKETKALSL-ARALEEALEAKEEFERQNKQLRADMED------------ 1515
            E   R   +   K TKAL   A+ + + L+     +R+  QL+  +E+            
Sbjct: 1649 ESEKRLRKDL--KRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKAR 1706

Query: 1516 --LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK 1573
              +    +D+   + ++ K+K ALE+Q+  ++ +  E+++ L+  ++    L    +A  
Sbjct: 1707 KAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAV 1766

Query: 1574 AQFERDL------QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627
            AQ  RDL      Q + E+  ++K+ L ++++ L++++E   +Q  +  +   + E  ++
Sbjct: 1767 AQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEF-LEQSMVDKSLVSRQEAKIR 1825

Query: 1628 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1687
            +LE ++E         +K+L  L +++K+   +L E R  R  I A+++E E+  K L+ 
Sbjct: 1826 ELETRLEFERTQ----VKRLESLASRLKENMEKLTEERDQR--IAAENREKEQN-KRLQR 1878

Query: 1688 EILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEE 1747
            ++   +EE+    R    A +++ EL  ++ +  +   +L  + +    RI  L+  +E+
Sbjct: 1879 QLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED 1938

Query: 1748 E---QSNMELLN 1756
            E     N +L+N
Sbjct: 1939 EMESDENEDLIN 1950



 Score =  115 bits (287), Expect = 6e-25
 Identities = 131/601 (21%), Positives = 264/601 (43%), Gaps = 94/601 (15%)

Query: 1385 GTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVAS 1444
            GT+  LEE + +       L Q      LA    +K K      + DL +     R V  
Sbjct: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRK------IQDLAI-----RCVQK 1223

Query: 1445 NLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFER 1504
            N+ KK K        +   + R   E   +E + R K+ +   L   LE+A + + E   
Sbjct: 1224 NI-KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRL 1282

Query: 1505 QNKQLRADMEDLMSSKDD---VGKNVHELEKSKRA----LEQQVEEMRTQLEELEDELQA 1557
             + +L + + +L S   D    G++  +L  ++ A     E++++E++TQ + L+ +++ 
Sbjct: 1283 NSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEV 1342

Query: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE--------KKRLLIKQV----RELEAEL 1605
             E         M+ M+A+  R  +   E +++        K    +++V    + L+ E 
Sbjct: 1343 ME---------MEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF 1393

Query: 1606 EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665
            ED+ +   +   +K+++E  L DL+A  E + +A  ++ K+ ++L A+++D +  LE  +
Sbjct: 1394 EDKLE---VEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQ 1450

Query: 1666 ASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERD-------------- 1711
                E+       EKK +  ++E+ Q  EE    +  R   ++E+D              
Sbjct: 1451 VRNHEL-------EKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLE 1503

Query: 1712 ------------------ELADEITNSASGKSALLDEKRRL---EARIAQLEEELEEEQS 1750
                              EL D  +  +  +++L   K++L   EA++   EEEL+E+  
Sbjct: 1504 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAG 1563

Query: 1751 NMELLNDRFRKTTLQVDTLNAELAAE-RSAAQKSDNARQQLERQNKELKAKLQELEGAVK 1809
             +++L     +  ++++ +    + E  S  ++ + ARQ  +++ K+++ +L+E E   K
Sbjct: 1564 TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDK 1622

Query: 1810 SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYK 1869
             K       LE K+  L +Q+ +   E        +R  K LK     + D +   D  K
Sbjct: 1623 QKVLREKRELEGKLATLSDQVNRRDFESE------KRLRKDLKRTKALLADAQLMLDHLK 1676

Query: 1870 EQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 1929
                 +   + QLK QLEE+E     A  +R+ ++ E++D     + +++  + L+ +L 
Sbjct: 1677 NSAP-SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735

Query: 1930 R 1930
            R
Sbjct: 1736 R 1736


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  503 bits (1295), Expect = e-142
 Identities = 374/1194 (31%), Positives = 594/1194 (49%), Gaps = 142/1194 (11%)

Query: 59   MVELAENGKKAMVNKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLK 106
            +V+L ++G+  +V+ +D            I+ M+P     VEDM  L  LNEA +L NL 
Sbjct: 27   VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86

Query: 107  DRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCML 166
             RY   LIYTY+G   V +NPY+ L IYS   I  Y  KK  EMPPHI+AI+++ Y  M 
Sbjct: 87   IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146

Query: 167  QDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILE 226
            ++  DQ  + +GESGAGKTE+TK ++Q+LA ++  H           +E+Q+L+A PILE
Sbjct: 147  RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197

Query: 227  SFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQ 286
            +FGNAKT++NDNSSRFGK+I I+F+  G I GA IE YLLEKSR  RQA DER +H+FY 
Sbjct: 198  AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257

Query: 287  LLSGAGEHLKSDLLLEGFNNYRFLSNG-YIPIPGQQDKDNFQETMEAMHIMGFSHEEILS 345
            +L G  E  K  L L   ++Y +L+ G  I   G+ D   +     AM ++ F+  E   
Sbjct: 258  MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317

Query: 346  MLKVVSSVLQFGNISFKKE--RNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKV 403
            + K+++++L  GN+ ++     N D   +  +        LL +N  +    + +  +  
Sbjct: 318  ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLIT 377

Query: 404  GRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGAS----FIGILD 459
              + V    ++EQA    +A  K  Y RLF W+V +IN A+ +   Q        IG+LD
Sbjct: 378  RGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLD 437

Query: 460  IAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI 519
            I GFE F +NSFEQLCIN+ NE LQQ F   +F LEQEEY  E I+W  I+F  D Q  +
Sbjct: 438  IFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDAL 496

Query: 520  DLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIH 579
            D+I     P  +++L+DEE  FPK TD T + KL  +   ++ +  P+    +  F I H
Sbjct: 497  DMIAN--KPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGINH 553

Query: 580  YAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAF 639
            +AG V Y+   +L KN D L+ ++  L+H S ++F+ ++++               + A 
Sbjct: 554  FAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ--------------ADVAM 599

Query: 640  GSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQL 699
            G+  + +     T+   +K SL  LM TL    P FVRCI PN  K+    D HL + QL
Sbjct: 600  GAETRKRS---PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQL 656

Query: 700  RCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFM-DGKQACERMIRALELDP 758
            R +G++E IRI R G+P R  F EF +RY +L P   P     D +  C+RM  A+    
Sbjct: 657  RYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTH 716

Query: 759  NLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKV 818
            + ++IG++KIF +      LE ERD  ITD +I  Q V RG+  R  F K +   +A  +
Sbjct: 717  DDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLK---NAATL 773

Query: 819  LQRNCAAYLKLRHWQWWRV-FTKVKPLLQVTRQEEELQAKDEELLKVKEK---------- 867
            +QR+   +   +++   R+ F +++ L +  +  ++ +   + +++ + +          
Sbjct: 774  IQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAF 833

Query: 868  ----------QTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK 917
                      Q    G +    R HQ+L  E      +L+AE    AE E++R  ++AKK
Sbjct: 834  RHRLWAVLTVQAYARGMI--ARRLHQRLRAE---YLWRLEAEKMRLAEEEKLRKEMSAKK 888

Query: 918  QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE 977
                          +EE ER    +++++  Q   +D E +L E+E AR+K +L +    
Sbjct: 889  -------------AKEEAER----KHQERLAQLAREDAERELKEKEAARRKKELLEQMER 931

Query: 978  AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037
            A+ + +    ++  D+   F+     +  +  +  S   + E         R ++E++  
Sbjct: 932  ARHEPVNHSDMV--DKMFGFLGTSGGLPGQEGQAPSGFEDLE---------RGRREMVEE 980

Query: 1038 DLEERLKKEEKTRQELEK------AKRKLDGETT----------------DLQDQIAELQ 1075
            DL+  L   ++  ++L +      A     G TT                D  DQ+A L 
Sbjct: 981  DLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALA 1040

Query: 1076 AQIDELKLQLAKKEEELQGALARGDD---------ETLHKNNALKVVRELQ----AQIAE 1122
              I  L+      E +   A++ G +         ETL K    + ++ LQ    AQ+ E
Sbjct: 1041 VWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPE 1100

Query: 1123 LQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1176
             Q+         +   K+K  L+EE+     + E T+   +  ++  T   +++
Sbjct: 1101 GQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGNSMLEDRPTSNLEKL 1154


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  503 bits (1295), Expect = e-142
 Identities = 374/1194 (31%), Positives = 594/1194 (49%), Gaps = 142/1194 (11%)

Query: 59   MVELAENGKKAMVNKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLK 106
            +V+L ++G+  +V+ +D            I+ M+P     VEDM  L  LNEA +L NL 
Sbjct: 27   VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86

Query: 107  DRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCML 166
             RY   LIYTY+G   V +NPY+ L IYS   I  Y  KK  EMPPHI+AI+++ Y  M 
Sbjct: 87   IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146

Query: 167  QDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILE 226
            ++  DQ  + +GESGAGKTE+TK ++Q+LA ++  H           +E+Q+L+A PILE
Sbjct: 147  RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197

Query: 227  SFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQ 286
            +FGNAKT++NDNSSRFGK+I I+F+  G I GA IE YLLEKSR  RQA DER +H+FY 
Sbjct: 198  AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257

Query: 287  LLSGAGEHLKSDLLLEGFNNYRFLSNG-YIPIPGQQDKDNFQETMEAMHIMGFSHEEILS 345
            +L G  E  K  L L   ++Y +L+ G  I   G+ D   +     AM ++ F+  E   
Sbjct: 258  MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317

Query: 346  MLKVVSSVLQFGNISFKKE--RNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKV 403
            + K+++++L  GN+ ++     N D   +  +        LL +N  +    + +  +  
Sbjct: 318  ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLIT 377

Query: 404  GRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGAS----FIGILD 459
              + V    ++EQA    +A  K  Y RLF W+V +IN A+ +   Q        IG+LD
Sbjct: 378  RGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLD 437

Query: 460  IAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI 519
            I GFE F +NSFEQLCIN+ NE LQQ F   +F LEQEEY  E I+W  I+F  D Q  +
Sbjct: 438  IFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDAL 496

Query: 520  DLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIH 579
            D+I     P  +++L+DEE  FPK TD T + KL  +   ++ +  P+    +  F I H
Sbjct: 497  DMIAN--KPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGINH 553

Query: 580  YAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAF 639
            +AG V Y+   +L KN D L+ ++  L+H S ++F+ ++++               + A 
Sbjct: 554  FAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ--------------ADVAM 599

Query: 640  GSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQL 699
            G+  + +     T+   +K SL  LM TL    P FVRCI PN  K+    D HL + QL
Sbjct: 600  GAETRKRS---PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQL 656

Query: 700  RCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFM-DGKQACERMIRALELDP 758
            R +G++E IRI R G+P R  F EF +RY +L P   P     D +  C+RM  A+    
Sbjct: 657  RYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTH 716

Query: 759  NLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKV 818
            + ++IG++KIF +      LE ERD  ITD +I  Q V RG+  R  F K +   +A  +
Sbjct: 717  DDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLK---NAATL 773

Query: 819  LQRNCAAYLKLRHWQWWRV-FTKVKPLLQVTRQEEELQAKDEELLKVKEK---------- 867
            +QR+   +   +++   R+ F +++ L +  +  ++ +   + +++ + +          
Sbjct: 774  IQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAF 833

Query: 868  ----------QTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK 917
                      Q    G +    R HQ+L  E      +L+AE    AE E++R  ++AKK
Sbjct: 834  RHRLWAVLTVQAYARGMI--ARRLHQRLRAE---YLWRLEAEKMRLAEEEKLRKEMSAKK 888

Query: 918  QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE 977
                          +EE ER    +++++  Q   +D E +L E+E AR+K +L +    
Sbjct: 889  -------------AKEEAER----KHQERLAQLAREDAERELKEKEAARRKKELLEQMER 931

Query: 978  AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037
            A+ + +    ++  D+   F+     +  +  +  S   + E         R ++E++  
Sbjct: 932  ARHEPVNHSDMV--DKMFGFLGTSGGLPGQEGQAPSGFEDLE---------RGRREMVEE 980

Query: 1038 DLEERLKKEEKTRQELEK------AKRKLDGETT----------------DLQDQIAELQ 1075
            DL+  L   ++  ++L +      A     G TT                D  DQ+A L 
Sbjct: 981  DLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALA 1040

Query: 1076 AQIDELKLQLAKKEEELQGALARGDD---------ETLHKNNALKVVRELQ----AQIAE 1122
              I  L+      E +   A++ G +         ETL K    + ++ LQ    AQ+ E
Sbjct: 1041 VWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPE 1100

Query: 1123 LQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1176
             Q+         +   K+K  L+EE+     + E T+   +  ++  T   +++
Sbjct: 1101 GQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGNSMLEDRPTSNLEKL 1154


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  503 bits (1295), Expect = e-142
 Identities = 374/1194 (31%), Positives = 594/1194 (49%), Gaps = 142/1194 (11%)

Query: 59   MVELAENGKKAMVNKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLK 106
            +V+L ++G+  +V+ +D            I+ M+P     VEDM  L  LNEA +L NL 
Sbjct: 27   VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86

Query: 107  DRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCML 166
             RY   LIYTY+G   V +NPY+ L IYS   I  Y  KK  EMPPHI+AI+++ Y  M 
Sbjct: 87   IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146

Query: 167  QDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILE 226
            ++  DQ  + +GESGAGKTE+TK ++Q+LA ++  H           +E+Q+L+A PILE
Sbjct: 147  RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197

Query: 227  SFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQ 286
            +FGNAKT++NDNSSRFGK+I I+F+  G I GA IE YLLEKSR  RQA DER +H+FY 
Sbjct: 198  AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257

Query: 287  LLSGAGEHLKSDLLLEGFNNYRFLSNG-YIPIPGQQDKDNFQETMEAMHIMGFSHEEILS 345
            +L G  E  K  L L   ++Y +L+ G  I   G+ D   +     AM ++ F+  E   
Sbjct: 258  MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317

Query: 346  MLKVVSSVLQFGNISFKKE--RNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKV 403
            + K+++++L  GN+ ++     N D   +  +        LL +N  +    + +  +  
Sbjct: 318  ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLIT 377

Query: 404  GRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGAS----FIGILD 459
              + V    ++EQA    +A  K  Y RLF W+V +IN A+ +   Q        IG+LD
Sbjct: 378  RGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLD 437

Query: 460  IAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI 519
            I GFE F +NSFEQLCIN+ NE LQQ F   +F LEQEEY  E I+W  I+F  D Q  +
Sbjct: 438  IFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDAL 496

Query: 520  DLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIH 579
            D+I     P  +++L+DEE  FPK TD T + KL  +   ++ +  P+    +  F I H
Sbjct: 497  DMIAN--KPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGINH 553

Query: 580  YAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAF 639
            +AG V Y+   +L KN D L+ ++  L+H S ++F+ ++++               + A 
Sbjct: 554  FAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQ--------------ADVAM 599

Query: 640  GSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQL 699
            G+  + +     T+   +K SL  LM TL    P FVRCI PN  K+    D HL + QL
Sbjct: 600  GAETRKRS---PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQL 656

Query: 700  RCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFM-DGKQACERMIRALELDP 758
            R +G++E IRI R G+P R  F EF +RY +L P   P     D +  C+RM  A+    
Sbjct: 657  RYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTH 716

Query: 759  NLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKV 818
            + ++IG++KIF +      LE ERD  ITD +I  Q V RG+  R  F K +   +A  +
Sbjct: 717  DDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLK---NAATL 773

Query: 819  LQRNCAAYLKLRHWQWWRV-FTKVKPLLQVTRQEEELQAKDEELLKVKEK---------- 867
            +QR+   +   +++   R+ F +++ L +  +  ++ +   + +++ + +          
Sbjct: 774  IQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAF 833

Query: 868  ----------QTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKK 917
                      Q    G +    R HQ+L  E      +L+AE    AE E++R  ++AKK
Sbjct: 834  RHRLWAVLTVQAYARGMI--ARRLHQRLRAE---YLWRLEAEKMRLAEEEKLRKEMSAKK 888

Query: 918  QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE 977
                          +EE ER    +++++  Q   +D E +L E+E AR+K +L +    
Sbjct: 889  -------------AKEEAER----KHQERLAQLAREDAERELKEKEAARRKKELLEQMER 931

Query: 978  AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037
            A+ + +    ++  D+   F+     +  +  +  S   + E         R ++E++  
Sbjct: 932  ARHEPVNHSDMV--DKMFGFLGTSGGLPGQEGQAPSGFEDLE---------RGRREMVEE 980

Query: 1038 DLEERLKKEEKTRQELEK------AKRKLDGETT----------------DLQDQIAELQ 1075
            DL+  L   ++  ++L +      A     G TT                D  DQ+A L 
Sbjct: 981  DLDAALPLPDEDEEDLSEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALA 1040

Query: 1076 AQIDELKLQLAKKEEELQGALARGDD---------ETLHKNNALKVVRELQ----AQIAE 1122
              I  L+      E +   A++ G +         ETL K    + ++ LQ    AQ+ E
Sbjct: 1041 VWITILRFMGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPE 1100

Query: 1123 LQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1176
             Q+         +   K+K  L+EE+     + E T+   +  ++  T   +++
Sbjct: 1101 GQKKSSVRHKLVHLTLKKKSKLTEEVTKRLHDGESTVQGNSMLEDRPTSNLEKL 1154


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  497 bits (1279), Expect = e-140
 Identities = 333/994 (33%), Positives = 548/994 (55%), Gaps = 71/994 (7%)

Query: 67   KKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVIN 126
            K++ +    +  M+P     V+DMA LT L+  S+++NL  RY    IYTY G     +N
Sbjct: 45   KQSTITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVN 104

Query: 127  PYKNLP-IYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKT 185
            PY+ +  +Y    +E Y  +   E+PPHI+AI+   YRC+ +  ++Q IL +GESGAGKT
Sbjct: 105  PYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKT 164

Query: 186  ENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKF 245
            E+TK ++++L+ ++              +ER +L+++PI+E+FGNAKTV N+NSSRFGKF
Sbjct: 165  ESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKF 224

Query: 246  IRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN 305
            +++N    G I G  I  YLLEK+R VRQ   ER +HIFY LL+G     + +  L    
Sbjct: 225  VQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPE 284

Query: 306  NYRFLS-NGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKE 364
            NY +L+ +G +      D+++F+E + AM +M FS EE+  + ++++ +L  GNI F   
Sbjct: 285  NYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF--- 341

Query: 365  RNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEAL 424
                 A +   T   +   LLG++  + T A+    + +  + +      +QA  + ++L
Sbjct: 342  ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSL 401

Query: 425  AKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQ 484
            A A Y   F W++ +IN  +     +    IGILDI GFE FE+N FEQ  INY NEKLQ
Sbjct: 402  AMALYACCFEWVIKKINSRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQ 459

Query: 485  QLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKA 544
            + FN  +F LEQ EY REG+ W  ID+ +D   C+DLIE+     G+LAL++EE  FP+A
Sbjct: 460  EYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL---GLLALINEESHFPQA 515

Query: 545  TDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVA 604
            TD T +EKL  +  ++  + KPR   +  +F + HYAG+V Y     L KN D   D++ 
Sbjct: 516  TDSTLLEKLHSQHANNHFYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLL 573

Query: 605  TLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKL 664
             LL +S   F+ +L++ V      D +        GS ++       TV   +K+SL  L
Sbjct: 574  NLLRESRFDFIYDLFEHVSSRNNQDTL------KCGSKHRRP-----TVSSQFKDSLHSL 622

Query: 665  MATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEF 724
            MATL ++NP FVRCI PN +K   + D  +VL+QLR +G+LE +RI + G+  R  FQ+F
Sbjct: 623  MATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDF 682

Query: 725  RQRYEILTPN-AIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERD 783
             +RY++L  N A+P+   D +  C  +++  +   + +++G++K+F R  +   LE+ R+
Sbjct: 683  YKRYKVLMRNLALPE---DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRRE 739

Query: 784  LKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWR----VFT 839
             +++   +  +A   G+LARK + K    L  + ++Q+N  A+L  R +   +    VF 
Sbjct: 740  EEVSHAAMVIRAHVLGFLARKQYRK---VLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQ 796

Query: 840  KVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAE 899
            K        R   +L A+  E  + K+++ + + + EE ER+ ++   E  + A+Q + E
Sbjct: 797  KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQ-EEE 855

Query: 900  TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
            T    E E ++     K Q+  E+  +LE + +E ++  +IL+ EK+     I+DL+   
Sbjct: 856  TRKQQELEALQ-----KSQKEAELTRELEKQ-KENKQVEEILRLEKE-----IEDLQRMK 904

Query: 960  DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKE--KKLMEDRIAEC------ 1011
            +++E +  +  L+K+      ++ ++E+  LE++  +  +E  + L  D I EC      
Sbjct: 905  EQQELSLTEASLQKLQ-----ERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIER 959

Query: 1012 --------SSQLAE---EEEKAKNLAKIRNKQEV 1034
                    SS+LAE   EE+   N ++   ++EV
Sbjct: 960  SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEV 993



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 74/300 (24%), Positives = 135/300 (45%), Gaps = 39/300 (13%)

Query: 1472 DRAEAEAREKETKALSLARALEEALEAKEEFERQNKQL--RADMEDLMSSKDD------- 1522
            D + +E +  +TK   L  +LE+ LE + E E  +  +  RA +   ++ K         
Sbjct: 711  DASNSEWQLGKTKVF-LRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCV 769

Query: 1523 --VGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580
              + KN       +R L  +   +  Q ++L  ++      +L  E   Q  K + E + 
Sbjct: 770  VIIQKNYRAFLLRRRFLHLKKAAIVFQ-KQLRGQIARRVYRQLLAEKREQEEKKKQEEEE 828

Query: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDE-RKQRALAVASKKKMEIDL-KDLEAQIEAANK 1638
            + + E+ EE++R   ++  EL A+ E+E RKQ+ L    K + E +L ++LE Q E  NK
Sbjct: 829  KKKREE-EERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKE--NK 885

Query: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQ--SKESEKKLKSLEAEILQLQEEL 1696
              +E++    +L+ +++D QR  E+   S  E   Q   +  +++L+ LE E  +  +E 
Sbjct: 886  QVEEIL----RLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEF 941

Query: 1697 ASS------ERARRHAEQE---RDELADEITNSASGKSALLDEKRRLEARIAQLEEELEE 1747
              S      +   R+ E+      E + E+  SA       +EK          EEE++E
Sbjct: 942  LESLNFDEIDECVRNIERSLSVGSEFSSELAESA------CEEKPNFNFSQPYPEEEVDE 995



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 85/378 (22%), Positives = 160/378 (42%), Gaps = 61/378 (16%)

Query: 1241 KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR------LRVELAEKASKLQNELDNVST 1294
            KVL +  A  E  R K  + +Q   A  SE         LR  L +K  K + E  + + 
Sbjct: 687  KVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAA 746

Query: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
            ++  A   G    K    +   +     ++Q+  R  L    R R L  +K ++  Q++ 
Sbjct: 747  MVIRAHVLGFLARKQYRKVLYCVV----IIQKNYRAFL---LRRRFLHLKKAAIVFQKQL 799

Query: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
              +  + + +Q+LA + +  + KK+ +++    E  E  +++  ++AE  +Q+ EE    
Sbjct: 800  RGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE---- 855

Query: 1415 YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ--KKFDQLLAEEKSIS--ARYAEE 1470
                     R QQEL+ L      + ++   LEK++  K+ +++L  EK I    R  E+
Sbjct: 856  --------TRKQQELEALQKS-QKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQ 906

Query: 1471 RDRAEAEA---REKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNV 1527
            ++ +  EA   + +E +   L R  EEA  A +EF          +E L  + D++ + V
Sbjct: 907  QELSLTEASLQKLQERRDQELRRLEEEACRAAQEF----------LESL--NFDEIDECV 954

Query: 1528 HELEKSKRALEQQVEEMRTQL---------------EELEDELQATEDA-KLRLEVNMQA 1571
              +E+S     +   E+                   EE+++  +A +DA K     +   
Sbjct: 955  RNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHG 1014

Query: 1572 MKAQFERDLQTRDEQNEE 1589
               Q    ++T D+ +EE
Sbjct: 1015 HSDQRTSGIRTSDDSSEE 1032



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 41/144 (28%), Positives = 76/144 (52%), Gaps = 27/144 (18%)

Query: 1040 EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARG 1099
            E+R ++E+K ++E EK KR+ +    + + + AEL+AQ +E      +K++EL+ AL + 
Sbjct: 814  EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELE-ALQKS 868

Query: 1100 DDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK--TELED 1157
              E                  AEL  + E +K   NK  ++   L +E+E L+   E ++
Sbjct: 869  QKE------------------AELTRELEKQK--ENKQVEEILRLEKEIEDLQRMKEQQE 908

Query: 1158 TLDTTAAQQELRTKREQEVAELKK 1181
               T A+ Q+L+ +R+QE+  L++
Sbjct: 909  LSLTEASLQKLQERRDQELRRLEE 932



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 47/196 (23%), Positives = 93/196 (47%), Gaps = 30/196 (15%)

Query: 1439 QRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEA 1498
            Q+Q+   + ++   + QLLAE+     R  EE+ + E E ++K            E  E 
Sbjct: 796  QKQLRGQIARRV--YRQLLAEK-----REQEEKKKQEEEEKKKR-----------EEEER 837

Query: 1499 KEEFERQNKQLRADMEDLMSSKDDV---------GKNVHELEKSKRALEQQVEEMRTQLE 1549
            + E ER+  +LRA  E+    + ++          +   ELEK K    +QVEE+    +
Sbjct: 838  ERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKE--NKQVEEILRLEK 895

Query: 1550 ELEDELQATEDAKLRL-EVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDE 1608
            E+ED  +  E  +L L E ++Q ++ + +++L+  +E+     +  ++ +   E +    
Sbjct: 896  EIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVR 955

Query: 1609 RKQRALAVASKKKMEI 1624
              +R+L+V S+   E+
Sbjct: 956  NIERSLSVGSEFSSEL 971



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 53/243 (21%), Positives = 105/243 (43%), Gaps = 56/243 (23%)

Query: 1089 EEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLS--- 1145
            +++L+G +AR            +V R+L A+  E +E  + E+  + K E+++R+     
Sbjct: 796  QKQLRGQIAR------------RVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERER 843

Query: 1146 ----------------EELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKN 1189
                            +ELEAL+   ++   T   +++   K+ +E+  L+K +E+    
Sbjct: 844  REAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIED---- 899

Query: 1190 HEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEV--KVLQQVK 1247
                +Q M+++   +L E S Q  Q +R     ++  + LE    E AC    + L+ + 
Sbjct: 900  ----LQRMKEQQELSLTEASLQKLQERR-----DQELRRLE----EEACRAAQEFLESLN 946

Query: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
             +      ++D  V+ +   +S G     ELAE A + +   +      EE   +G +  
Sbjct: 947  FD------EIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEAD 1000

Query: 1308 KDA 1310
             DA
Sbjct: 1001 DDA 1003



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 59/262 (22%), Positives = 110/262 (41%), Gaps = 58/262 (22%)

Query: 1657 YQREL--EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
            +Q++L  + AR    ++ A+ +E E+K K         QEE    E  ++  E+ER+   
Sbjct: 795  FQKQLRGQIARRVYRQLLAEKREQEEKKK---------QEE----EEKKKREEEERER-- 839

Query: 1715 DEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1774
                           E+ R EA +   +EE   +Q  +E          LQ     AEL 
Sbjct: 840  ---------------ERERREAELRAQQEEETRKQQELE---------ALQKSQKEAELT 875

Query: 1775 AERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA 1834
             E          +Q+  +Q +E+    +E+E   + K +  +S  EA + +L+E+ +QE 
Sbjct: 876  RELE--------KQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQEL 927

Query: 1835 KERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL-EEAEEEA 1893
              R    +  R  ++ L+ +           D+    +E++ +   +   +L E A EE 
Sbjct: 928  --RRLEEEACRAAQEFLESLNFD------EIDECVRNIERSLSVGSEFSSELAESACEEK 979

Query: 1894 TRANASRRKLQRELDDATEANE 1915
               N S+   + E+D+  EA++
Sbjct: 980  PNFNFSQPYPEEEVDEGFEADD 1001



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 81/355 (22%), Positives = 158/355 (44%), Gaps = 47/355 (13%)

Query: 799  GYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQV-TRQEEELQAK 857
            GY  R+ F   Q      KVL RN A    +R         K   LLQ+      E Q  
Sbjct: 672  GYAVRRPF---QDFYKRYKVLMRNLALPEDVRG--------KCTSLLQLYDASNSEWQLG 720

Query: 858  DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILA--EQLQAETELFAEA---EEMRAR 912
              ++   +  + K+E   EE E  H  ++   ++L    + Q    L+      +  RA 
Sbjct: 721  KTKVFLRESLEQKLEKRREE-EVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAF 779

Query: 913  LAAKKQELEEILHDLESRVEEEEE-RNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQL 971
            L  ++      LH  ++ +  +++ R QI +   +++ A  ++ EE+  +EE  ++K + 
Sbjct: 780  LLRRR-----FLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREE 834

Query: 972  EKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNK 1031
            E+   E + ++ E E+   +++ ++  K+++L   + ++  ++L  E EK K      NK
Sbjct: 835  EE--RERERERREAELRAQQEEETR--KQQELEALQKSQKEAELTRELEKQK-----ENK 885

Query: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1091
            Q        E + + EK  ++L++ K + +   T+     A LQ   +    +L + EEE
Sbjct: 886  Q-------VEEILRLEKEIEDLQRMKEQQELSLTE-----ASLQKLQERRDQELRRLEEE 933

Query: 1092 LQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSE 1146
               A A+   E+L+ +   + VR ++  ++ +  +F SE A     EK   + S+
Sbjct: 934  ACRA-AQEFLESLNFDEIDECVRNIERSLS-VGSEFSSELAESACEEKPNFNFSQ 986



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 46/172 (26%), Positives = 84/172 (48%), Gaps = 22/172 (12%)

Query: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645
            Q + + ++  +  R+L AE  ++ +++      KKK E + ++ E +   A         
Sbjct: 796  QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREA--------- 846

Query: 1646 QLRKLQAQMKDYQRELEEARASRDEI-FAQSKESEKKLKSLEAEILQLQEELASSERARR 1704
            +LR  Q +    Q+ELE  + S+ E    +  E +K+ K +E EIL+L++E+   +R + 
Sbjct: 847  ELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVE-EILRLEKEIEDLQRMK- 904

Query: 1705 HAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLN 1756
                E+ EL+  +T ++  K   L E+R  E R  + EE     Q  +E LN
Sbjct: 905  ----EQQELS--LTEASLQK---LQERRDQELRRLE-EEACRAAQEFLESLN 946


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,185,536
Number of Sequences: 37866
Number of extensions: 3186319
Number of successful extensions: 100339
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1066
Number of HSP's successfully gapped in prelim test: 1777
Number of HSP's that attempted gapping in prelim test: 16993
Number of HSP's gapped (non-prelim): 24419
length of query: 1976
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1859
effective length of database: 13,817,196
effective search space: 25686167364
effective search space used: 25686167364
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.