Guide to the Human Genome
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Search of human proteins with 40217833

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40217833 G protein-coupled receptor family C, group 5,
member C isoform b [Homo sapiens]
         (453 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40217833 G protein-coupled receptor family C, group 5, member...   925   0.0  
gi|40217831 G protein-coupled receptor family C, group 5, member...   923   0.0  
gi|7706451 G protein-coupled receptor, family C, group 5, member...   275   5e-74
gi|4506403 G protein-coupled receptor, family C, group 5, member...   208   7e-54
gi|8923705 G protein-coupled receptor, family C, group 5, member...   198   1e-50
gi|66529100 glutamate receptor, metabotropic 2 isoform a precurs...    49   7e-06
gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo s...    47   5e-05
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr...    43   7e-04
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre...    42   0.001
gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]           39   0.007
gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo ...    39   0.013
gi|112807234 G protein-coupled receptor, family C, group 6, memb...    38   0.022
gi|37577159 calcium-sensing receptor [Homo sapiens]                    37   0.028
gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo ...    37   0.037
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]           35   0.14 
gi|209413763 hypothetical protein LOC11094 isoform b [Homo sapiens]    34   0.24 
gi|169171487 PREDICTED: hypothetical protein [Homo sapiens]            34   0.31 
gi|169171950 PREDICTED: hypothetical protein [Homo sapiens]            34   0.31 
gi|169171214 PREDICTED: hypothetical protein [Homo sapiens]            34   0.31 
gi|239509026 PREDICTED: hypothetical protein [Homo sapiens]            34   0.31 
gi|50233858 olfactory receptor, family 2, subfamily T, member 11...    30   3.4  
gi|38505226 E2F family member 8 [Homo sapiens]                         30   4.5  
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...    29   7.7  
gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]                    29   7.7  

>gi|40217833 G protein-coupled receptor family C, group 5, member C
           isoform b [Homo sapiens]
          Length = 453

 Score =  925 bits (2391), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MGTQPEPGLGARMAIHKALVMCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGA 60
           MGTQPEPGLGARMAIHKALVMCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGA
Sbjct: 1   MGTQPEPGLGARMAIHKALVMCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGA 60

Query: 61  WGIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACV 120
           WGIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACV
Sbjct: 61  WGIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACV 120

Query: 121 VKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEV 180
           VKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEV
Sbjct: 121 VKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEV 180

Query: 181 IINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAW 240
           IINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAW
Sbjct: 181 IINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAW 240

Query: 241 PALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTWDDPTLAIALAANA 300
           PALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTWDDPTLAIALAANA
Sbjct: 241 PALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTWDDPTLAIALAANA 300

Query: 301 WAFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEP 360
           WAFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEP
Sbjct: 301 WAFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEP 360

Query: 361 VAAKRPVSPYSGYNGQLLTSVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTL 420
           VAAKRPVSPYSGYNGQLLTSVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTL
Sbjct: 361 VAAKRPVSPYSGYNGQLLTSVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTL 420

Query: 421 RAEDMYSAQSHQAATPPKDGKNSQVFRNPYVWD 453
           RAEDMYSAQSHQAATPPKDGKNSQVFRNPYVWD
Sbjct: 421 RAEDMYSAQSHQAATPPKDGKNSQVFRNPYVWD 453


>gi|40217831 G protein-coupled receptor family C, group 5, member C
           isoform a [Homo sapiens]
          Length = 486

 Score =  923 bits (2386), Expect = 0.0
 Identities = 452/452 (100%), Positives = 452/452 (100%)

Query: 2   GTQPEPGLGARMAIHKALVMCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAW 61
           GTQPEPGLGARMAIHKALVMCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAW
Sbjct: 35  GTQPEPGLGARMAIHKALVMCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAW 94

Query: 62  GIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVV 121
           GIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVV
Sbjct: 95  GIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVV 154

Query: 122 KPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVI 181
           KPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVI
Sbjct: 155 KPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVI 214

Query: 182 INTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWP 241
           INTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWP
Sbjct: 215 INTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWP 274

Query: 242 ALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTWDDPTLAIALAANAW 301
           ALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTWDDPTLAIALAANAW
Sbjct: 275 ALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTWDDPTLAIALAANAW 334

Query: 302 AFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEPV 361
           AFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEPV
Sbjct: 335 AFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEPV 394

Query: 362 AAKRPVSPYSGYNGQLLTSVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTLR 421
           AAKRPVSPYSGYNGQLLTSVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTLR
Sbjct: 395 AAKRPVSPYSGYNGQLLTSVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTLR 454

Query: 422 AEDMYSAQSHQAATPPKDGKNSQVFRNPYVWD 453
           AEDMYSAQSHQAATPPKDGKNSQVFRNPYVWD
Sbjct: 455 AEDMYSAQSHQAATPPKDGKNSQVFRNPYVWD 486


>gi|7706451 G protein-coupled receptor, family C, group 5, member B
           precursor [Homo sapiens]
          Length = 403

 Score =  275 bits (704), Expect = 5e-74
 Identities = 160/395 (40%), Positives = 226/395 (57%), Gaps = 34/395 (8%)

Query: 12  RMAIHKALVMCLGLPLFLFPGAWAQG-HVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAG 70
           +M  H+ L   L   LF+     ++      GC   L P Y +LCD    WGIV+EAVAG
Sbjct: 8   KMRAHQVLTFLL---LFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAG 64

Query: 71  AGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCAS 130
           AG + T +L +IL+  LPF+++ +K+S +G    FLLGTLGLF L FA +++ D + C+ 
Sbjct: 65  AGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSV 124

Query: 131 RRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIIT 190
           RRFL+GVLFA+CFSCL +  + +  L R   GP GW +  +AL L LV+VII  EWL++T
Sbjct: 125 RRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEWLVLT 184

Query: 191 LVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRW 250
           ++R +                  CA   MDFVMALIY M+LL+     A   LCG++KRW
Sbjct: 185 VLRDT---------------RPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRW 229

Query: 251 RKHGVFVLLTTATSVAIWVVWIVMYTYGN-KQHNSPTWDDPTLAIALAANAWAFVLFYVI 309
           + +G F+L+T   SV IWV W+ MY +GN K      W+DPTLAI LAA+ W FV+F+ I
Sbjct: 230 KLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAI 289

Query: 310 PEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQ-KGQSMFVENKAFSMDEPVAAKRPVS 368
           PE+      + +++       ++    ET  +E  +    ++ENKAFSMDE  AA R   
Sbjct: 290 PEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAG 349

Query: 369 PYSGYNGQ-------------LLTSVYQPTEMALM 390
             +G  G+               ++VYQPTEMA++
Sbjct: 350 FPNGSLGKRPSGSLGKRPSAPFRSNVYQPTEMAVV 384


>gi|4506403 G protein-coupled receptor, family C, group 5, member A
           [Homo sapiens]
          Length = 357

 Score =  208 bits (530), Expect = 7e-54
 Identities = 125/322 (38%), Positives = 176/322 (54%), Gaps = 23/322 (7%)

Query: 39  VPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSL 98
           VP GC  GL   YY LCD++ AWGIVLE VA AG+VT+    + L   +  VQD+ +R +
Sbjct: 5   VPDGCRNGLKSKYYRLCDKAEAWGIVLETVATAGVVTSVAFMLTLPILVCKVQDSNRRKM 64

Query: 99  LGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLAR 158
           L TQ  FLLG LG+F L FA ++  D ST  +R FLFG+LF+ICFSCL AH  +L  L R
Sbjct: 65  LPTQFLFLLGVLGIFGLTFAFIIGLDGSTGPTRFFLFGILFSICFSCLLAHAVSLTKLVR 124

Query: 159 KNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIAN 218
                   VI  +A+  +LV+ +I  E++++T+ R         N +    +++P    N
Sbjct: 125 GRKPLSLLVILGLAVGFSLVQDVIAIEYIVLTMNR--------TNVNVFSELSAP--RRN 174

Query: 219 MDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYG 278
            DFV+ L YV+ L+   FL +    CG +  W++HG  + LT   S+AIWV WI +    
Sbjct: 175 EDFVLLLTYVLFLMALTFLMSSFTFCGSFTGWKRHGAHIYLTMLLSIAIWVAWITLLMLP 234

Query: 279 NKQHNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYET 338
           +       WDD  L+ ALAAN W F+L YV PE   +TK      Y  +         + 
Sbjct: 235 DFDRR---WDDTILSSALAANGWVFLLAYVSPEFWLLTKQRNPMDYPVE---------DA 282

Query: 339 ILKEQKGQSMF-VENKAFSMDE 359
             K Q  +  + VEN+A+S +E
Sbjct: 283 FCKPQLVKKSYGVENRAYSQEE 304


>gi|8923705 G protein-coupled receptor, family C, group 5, member D
           [Homo sapiens]
          Length = 345

 Score =  198 bits (503), Expect = 1e-50
 Identities = 109/296 (36%), Positives = 166/296 (56%), Gaps = 14/296 (4%)

Query: 51  YYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTL 110
           Y+ LCD  G WGI+LE++A  GIV T +L +  +  +  +QD  + ++L TQ+ FLL  L
Sbjct: 12  YFLLCDAEGPWGIILESLAILGIVVTILLLLAFLFLMRKIQDCSQWNVLPTQLLFLLSVL 71

Query: 111 GLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFT 170
           GLF L FA +++ +  T   R FLFGVLFA+CFSCL AH   L  L R         I  
Sbjct: 72  GLFGLAFAFIIELNQQTAPVRYFLFGVLFALCFSCLLAHASNLVKLVRGCVSFSWTTILC 131

Query: 171 VALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVML 230
           +A+  +L+++II TE++ + + RG             +   +PC + N+DFV+ L+YV+ 
Sbjct: 132 IAIGCSLLQIIIATEYVTLIMTRG-----------MMFVNMTPCQL-NVDFVVLLVYVLF 179

Query: 231 LLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQ-HNSPTWDD 289
           L+   F  +    CG  + W++HG  + +T   S+ IWVVWI M   GN Q    P WDD
Sbjct: 180 LMALTFFVSKATFCGPCENWKQHGRLIFITVLFSIIIWVVWISMLLRGNPQFQRQPQWDD 239

Query: 290 PTLAIALAANAWAFVLFYVIPEVSQVTKSSPEQ-SYQGDMYPTRGVGYETILKEQK 344
           P + IAL  NAW F+L Y++PE+  + +S  ++   QG+  P     +   ++ Q+
Sbjct: 240 PVVCIALVTNAWVFLLLYIVPELCILYRSCRQECPLQGNACPVTAYQHSFQVENQE 295


>gi|66529100 glutamate receptor, metabotropic 2 isoform a precursor
           [Homo sapiens]
          Length = 872

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 58/235 (24%), Positives = 95/235 (40%), Gaps = 39/235 (16%)

Query: 60  AWGIVLEAVAGAG-IVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGL-FCLVF 117
           AW +    +A  G + T FVL + +  +   V     R L     + LLG + L +C+ F
Sbjct: 566 AWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELC----YILLGGVFLCYCMTF 621

Query: 118 ACVVKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWV--------IF 169
             + KP  + C  RR   G  F++C+S L       N +AR   G R             
Sbjct: 622 IFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKT---NRIARIFGGAREGAQRPRFISPAS 678

Query: 170 TVALLLTLV--EVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIY 227
            VA+ L L+  +++I   WL++       E  P+        V   C   +   + +L Y
Sbjct: 679 QVAICLALISGQLLIVVAWLVVEAPGTGKETAPERRE----VVTLRCNHRDASMLGSLAY 734

Query: 228 VMLLLLGAFLGAWPALCGRYK-RWRK------HGVFVLLTTATSVAIWVVWIVMY 275
            +LL+         ALC  Y  + RK         F+  T  T+  IW+ ++ ++
Sbjct: 735 NVLLI---------ALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIF 780


>gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo
           sapiens]
          Length = 879

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 61/271 (22%), Positives = 114/271 (42%), Gaps = 40/271 (14%)

Query: 60  AWGIVLEAVAGAGIVTTFVLTIILVA--SLPFVQDTKKRSLLGTQVFFLLGTLGL-FCLV 116
           AW I    +A  G + T ++  + +   + P V+ + +        + LL  +GL +C+ 
Sbjct: 575 AWAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRELC-----YILLFGVGLSYCMT 629

Query: 117 FACVVKPDFSTCASRRFLFGVLFAICFSCL--AAHVFALNFLARKNHGPRGWVI-----F 169
           F  + KP    CA RR   G  FAIC+S L    +  A  F   KN   R   I      
Sbjct: 630 FFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQV 689

Query: 170 TVALLLTLVEVIINTEWLIITLVRGSGEGGPQGN-SSAGWAVASPCAIANMDFVMALIYV 228
            + L L LV++++ + WLI+        G  +   +     V   C + +   +++L Y 
Sbjct: 690 FICLGLILVQIVMVSVWLIL-----EAPGTRRYTLAEKRETVILKCNVKDSSMLISLTYD 744

Query: 229 MLLLLGAFLGAWPALCGRYK-RWRK------HGVFVLLTTATSVAIWVVWIVMYTYGNKQ 281
           ++L++         LC  Y  + RK         F+  T  T+  IW+ ++ ++   +  
Sbjct: 745 VILVI---------LCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSD 795

Query: 282 HNSPTWDDPTLAIALAANAWAFVLFYVIPEV 312
           +   T    T+ I+++ + +  +     P+V
Sbjct: 796 YRVQT---TTMCISVSLSGFVVLGCLFAPKV 823


>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
           precursor [Homo sapiens]
          Length = 1194

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 77/346 (22%), Positives = 133/346 (38%), Gaps = 43/346 (12%)

Query: 46  GLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVA--SLPFVQDTKKRSLLGTQV 103
           G  P+     + S    I+  A +  GI+ T  +T+I V     P V+ + +        
Sbjct: 577 GCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILA 636

Query: 104 FFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLA------AHVFA---LN 154
              LG    +   F  + KP  ++C  +R L G+  A+C+S L       A + A     
Sbjct: 637 GIFLG----YVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKK 692

Query: 155 FLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPC 214
              RK      W    +A +L  V++      L++TL+       P  +  +   V   C
Sbjct: 693 ICTRKPRFMSAWAQVIIASILISVQLT-----LVVTLII-MEPPMPILSYPSIKEVYLIC 746

Query: 215 AIANMDFVMALIYVMLLLLGAFLGAW-----PALCGRYKRWRKHGVFVLLTTATSVAIWV 269
             +N+  V  L Y  LL++     A+     PA     K       ++  T  T+  IW+
Sbjct: 747 NTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAK-------YIAFTMYTTCIIWL 799

Query: 270 VWIVMYTYGNKQHNSPTWDDPTLAIALAANAWAFVLFYVI---PE---VSQVTKSSPEQS 323
            ++ +Y +G+      T    +L++ +A         Y+I   PE    S  T S   + 
Sbjct: 800 AFVPIY-FGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRM 858

Query: 324 YQGD-MYPTRGVGYETILKEQKGQSMFVEN--KAFSMDEPVAAKRP 366
           + GD   P R   +  I + +K  +    +  K+ S  EP   + P
Sbjct: 859 HVGDGKLPCRSNTFLNIFRRKKAGAGNANSNGKSVSWSEPGGGQVP 904


>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
           precursor [Homo sapiens]
          Length = 906

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 72/322 (22%), Positives = 124/322 (38%), Gaps = 41/322 (12%)

Query: 46  GLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVA--SLPFVQDTKKRSLLGTQV 103
           G  P+     + S    I+  A +  GI+ T  +T+I V     P V+ + +        
Sbjct: 577 GCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILA 636

Query: 104 FFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLA------AHVFA---LN 154
              LG    +   F  + KP  ++C  +R L G+  A+C+S L       A + A     
Sbjct: 637 GIFLG----YVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKK 692

Query: 155 FLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPC 214
              RK      W    +A +L  V++      L++TL+       P  +  +   V   C
Sbjct: 693 ICTRKPRFMSAWAQVIIASILISVQLT-----LVVTLII-MEPPMPILSYPSIKEVYLIC 746

Query: 215 AIANMDFVMALIYVMLLLLGAFLGAW-----PALCGRYKRWRKHGVFVLLTTATSVAIWV 269
             +N+  V  L Y  LL++     A+     PA     K       ++  T  T+  IW+
Sbjct: 747 NTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAK-------YIAFTMYTTCIIWL 799

Query: 270 VWIVMYTYGNKQHNSPTWDDPTLAIALAANAWAFVLFYVI---PE---VSQVTKSSPEQS 323
            ++ +Y +G+      T    +L++ +A         Y+I   PE    S  T S   + 
Sbjct: 800 AFVPIY-FGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRM 858

Query: 324 YQGD-MYPTRGVGYETILKEQK 344
           + GD   P R   +  I + +K
Sbjct: 859 HVGDGKLPCRSNTFLNIFRRKK 880


>gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]
          Length = 839

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 63  IVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVV- 121
           I +  +A  G ++T  + +I        Q    RS  G   F +L  L +  +V    V 
Sbjct: 567 IAVALLAALGFLSTLAILVIFWRHF---QTPIVRSAGGPMCFLMLTLLLVAYMVVPVYVG 623

Query: 122 KPDFSTCASRRFLFGVLFAICFSCLAAHVFAL 153
            P  STC  R+ LF + F IC SC+A   F +
Sbjct: 624 PPKVSTCLCRQALFPLCFTICISCIAVRSFQI 655


>gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo
           sapiens]
          Length = 254

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 33/178 (18%)

Query: 115 LVFACVVKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWV------- 167
           + F  + KP  + C  RR   G  F++C+S L       N +AR   G R          
Sbjct: 1   MTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKT---NRIARIFGGAREGAQRPRFIS 57

Query: 168 -IFTVALLLTLV--EVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMA 224
               VA+ L L+  +++I   WL++       E  P+        V   C   +   + +
Sbjct: 58  PASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERRE----VVTLRCNHRDASMLGS 113

Query: 225 LIYVMLLLLGAFLGAWPALCGRYK-RWRK------HGVFVLLTTATSVAIWVVWIVMY 275
           L Y +LL+         ALC  Y  + RK         F+  T  T+  IW+ ++ ++
Sbjct: 114 LAYNVLLI---------ALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIF 162


>gi|112807234 G protein-coupled receptor, family C, group 6, member
           A [Homo sapiens]
          Length = 926

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 55/230 (23%), Positives = 90/230 (39%), Gaps = 31/230 (13%)

Query: 63  IVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVK 122
           I+L  ++  GI+   V+ II   +L          L    V  L   L      F     
Sbjct: 595 ILLLILSLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEP 654

Query: 123 PDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPR-----------GWVIFTV 171
            DF TC +R+ +FGV F +C SC+     +L  L   +  P+             +IFT 
Sbjct: 655 QDF-TCKTRQTMFGVSFTLCISCILTK--SLKILLAFSFDPKLQKFLKCLYRPILIIFT- 710

Query: 172 ALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIAN-MDFVMALIYVML 230
               T ++V+I T WLI            + N S    +   C   + + F   L Y+ +
Sbjct: 711 ---CTGIQVVICTLWLIFAAPT------VEVNVSLPRVIILECEEGSILAFGTMLGYIAI 761

Query: 231 LLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMY--TYG 278
           L    F+ A+    G+Y+ + +   F+          W+ +I +Y  T+G
Sbjct: 762 LAFICFIFAFK---GKYENYNE-AKFITFGMLIYFIAWITFIPIYATTFG 807


>gi|37577159 calcium-sensing receptor [Homo sapiens]
          Length = 1078

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 13/136 (9%)

Query: 61  WGIVLEAVAGAGI-VTTFVLTIIL-VASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFA 118
           +GI L   A  GI +T FVL + +   + P V+ T +          L   L  F     
Sbjct: 612 FGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRE----LSYLLLFSLLCCFSSSLF 667

Query: 119 CVVKPDFSTCASRRFLFGVLFAICFSCLAAHV--FALNFLAR-KNHGPRGW----VIFTV 171
            + +P   TC  R+  FG+ F +C SC+        L F A+      R W    + F +
Sbjct: 668 FIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFEAKIPTSFHRKWWGLNLQFLL 727

Query: 172 ALLLTLVEVIINTEWL 187
             L T ++++I   WL
Sbjct: 728 VFLCTFMQIVICVIWL 743


>gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo
           sapiens]
          Length = 877

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 56/273 (20%), Positives = 113/273 (41%), Gaps = 21/273 (7%)

Query: 64  VLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKP 123
           +L AV G    TT V T +   + P V+ + +          L G   ++ + F  V +P
Sbjct: 590 LLLAVLGIVATTTVVATFVRYNNTPIVRASGRE----LSYVLLTGIFLIYAITFLMVAEP 645

Query: 124 DFSTCASRRFLFGVLFAICFSCLAA---HVFALNFLARKNHGPRGWVIFTVALL----LT 176
             + CA+RR   G+   + +S L      ++ +    +++  P  ++  T  L+    LT
Sbjct: 646 GAAVCAARRLFLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLT 705

Query: 177 LVEVIINTEWLIITLVRGSGEGGPQGNSSAGWA-VASPCAIANMDFVMALIYVMLLLLGA 235
            ++V+    WL         +   Q       A     C ++++  +  L Y +LL++  
Sbjct: 706 SLQVVGMIAWLGARPPHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTC 765

Query: 236 FLGAWPA--LCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTW-DDPTL 292
            + A  A  +   +   +  G     T  T+  IW+ ++ ++ +G  Q     +    TL
Sbjct: 766 TVYAIKARGVPETFNEAKPIG----FTMYTTCIIWLAFVPIF-FGTAQSAEKIYIQTTTL 820

Query: 293 AIALAANAWAFVLFYVIPEVSQVTKSSPEQSYQ 325
            ++L+ +A   +    +P+ + V    PEQ+ Q
Sbjct: 821 TVSLSLSASVSLGMLYVPK-TYVILFHPEQNVQ 852


>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
          Length = 912

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 24/103 (23%), Positives = 42/103 (40%), Gaps = 6/103 (5%)

Query: 46  GLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFF 105
           G  P+     +    W ++   +A  GI  T  + I  V       DT      G ++ +
Sbjct: 572 GCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVR----YNDTPIVKASGRELSY 627

Query: 106 LL--GTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCL 146
           +L  G    +   F  + +PD  TC+ RR   G+  +I ++ L
Sbjct: 628 VLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAAL 670


>gi|209413763 hypothetical protein LOC11094 isoform b [Homo sapiens]
          Length = 130

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%)

Query: 31  PGAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGA-GIVTTFVLTI-----ILV 84
           PGA A    PP   +G+   Y  LC  SG  G V  A++G    +T   L I     +++
Sbjct: 8   PGASASS-APPAQEEGMTWWYRWLCRLSGVLGAVSCAISGLFNCITIHPLNIAAGVWMMM 66

Query: 85  ASLPFVQDTKKRSLLGTQVFFLLGTL 110
           A +P V      +LLG  + F  G L
Sbjct: 67  AVVPIVISLTLTTLLGNAIAFATGVL 92


>gi|169171487 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 176

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 9/104 (8%)

Query: 313 SQVTKSSPEQSYQGDMYP----TRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVS 368
           S+V    PE  +Q +MYP    TR + YE I  + +G+  ++  +   M E      P++
Sbjct: 73  SKVPSPVPEAPFQSEMYPVPPITRALLYEGISHDFQGRYRYLNTRKLDMPE-TRYLFPIT 131

Query: 369 PYSGYNGQLLTSVYQPTEMALMHKVPS----EGAYDIILPRATA 408
               Y  QL   V Q      M ++ S     GA+ ++ PR  A
Sbjct: 132 TSFTYGWQLGPPVKQELVSCKMCRIESFFRKNGAFALLDPRDLA 175


>gi|169171950 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 176

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 9/104 (8%)

Query: 313 SQVTKSSPEQSYQGDMYP----TRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVS 368
           S+V    PE  +Q +MYP    TR + YE I  + +G+  ++  +   M E      P++
Sbjct: 73  SKVPSPVPEAPFQSEMYPVPPITRALLYEGISHDFQGRYRYLNTRKLDMPE-TRYLFPIT 131

Query: 369 PYSGYNGQLLTSVYQPTEMALMHKVPS----EGAYDIILPRATA 408
               Y  QL   V Q      M ++ S     GA+ ++ PR  A
Sbjct: 132 TSFTYGWQLGPPVKQELVSCKMCRIESFFRKNGAFALLDPRDLA 175


>gi|169171214 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 176

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 9/104 (8%)

Query: 313 SQVTKSSPEQSYQGDMYP----TRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVS 368
           S+V    PE  +Q +MYP    TR + YE I  + +G+  ++  +   M E      P++
Sbjct: 73  SKVPSPVPEAPFQSEMYPVPPITRALLYEGISHDFQGRYRYLNTRKLDMPE-TRYLFPIT 131

Query: 369 PYSGYNGQLLTSVYQPTEMALMHKVPS----EGAYDIILPRATA 408
               Y  QL   V Q      M ++ S     GA+ ++ PR  A
Sbjct: 132 TSFTYGWQLGPPVKQELVSCKMCRIESFFRKNGAFALLDPRDLA 175


>gi|239509026 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 176

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 9/104 (8%)

Query: 313 SQVTKSSPEQSYQGDMYP----TRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVS 368
           S+V    PE  +Q +MYP    TR + YE I  + +G+  ++  +   M E      P++
Sbjct: 73  SKVPSPVPEAPFQSEMYPVPPITRALLYEGISHDFQGRYRYLNTRKLDMPE-TRYLFPIT 131

Query: 369 PYSGYNGQLLTSVYQPTEMALMHKVPS----EGAYDIILPRATA 408
               Y  QL   V Q      M ++ S     GA+ ++ PR  A
Sbjct: 132 TSFTYGWQLGPPVKQELVSCKMCRIESFFRKNGAFALLDPRDLA 175


>gi|50233858 olfactory receptor, family 2, subfamily T, member 11
           [Homo sapiens]
          Length = 316

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 4/65 (6%)

Query: 62  GIVLEAVAGAGIVTTFVLTIIL---VASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFA 118
           G+++ + A AGIV T +L + L    A+L  +   +  S L T ++FLL  L +   +F 
Sbjct: 13  GLLVNSEA-AGIVFTVILAVFLGAVTANLVMIFLIQVDSRLHTPMYFLLSQLSIMDTLFI 71

Query: 119 CVVKP 123
           C   P
Sbjct: 72  CTTVP 76


>gi|38505226 E2F family member 8 [Homo sapiens]
          Length = 867

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 30/131 (22%), Positives = 49/131 (37%), Gaps = 14/131 (10%)

Query: 313 SQVTKSSPEQSYQGDMYPTRGVGYETI----LKEQKGQSMFVENKAFSMDEPVAAKRPVS 368
           S +  +  E S     +P++      I    L+EQ  +S        +   P     P+ 
Sbjct: 417 SPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLD 476

Query: 369 PYSGYNGQLLT-SVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTLRAEDMYS 427
           P      +L   S+ QP  M  +   P   A  +ILP+A +             A  +  
Sbjct: 477 PPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSY---------AIYLQP 527

Query: 428 AQSHQAATPPK 438
            Q+HQ+ TPP+
Sbjct: 528 TQAHQSVTPPQ 538


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 20/68 (29%), Positives = 27/68 (39%)

Query: 197 EGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVF 256
           E GP  NS+  W    P A     +V A + V++ L  A      AL       R    F
Sbjct: 4   EPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNF 63

Query: 257 VLLTTATS 264
            L++  TS
Sbjct: 64  FLVSLFTS 71


>gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]
          Length = 710

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 13/71 (18%)

Query: 121 VKPD-FSTCASRRFLF----------GVLFAICFSCLAAHVFALNFLARKNHGPRGWVIF 169
           +K D F TCA R +            G +  +C SCL  H+ A   L ++NH   GW+  
Sbjct: 514 IKEDRFWTCAYRLYYALKEEKVFLGGGAVEFLCLSCL--HILAEQSLKKENHACSGWLHN 571

Query: 170 TVALLLTLVEV 180
           T + L + + +
Sbjct: 572 TSSWLASSLAI 582


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,995,469
Number of Sequences: 37866
Number of extensions: 795208
Number of successful extensions: 2475
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2449
Number of HSP's gapped (non-prelim): 26
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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