Search of human proteins with 40018638

Search of human proteins with 40018638

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40018638 C2 calcium-dependent domain containing 2 isoform 2
[Homo sapiens]
         (541 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40018638 C2 calcium-dependent domain containing 2 isoform 2 [...  1061   0.0  
gi|119226222 C2 calcium-dependent domain containing 2 isoform 1 ...  1061   0.0  
gi|42716277 transmembrane protein 24 [Homo sapiens]                   225   9e-59
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    42   0.002
gi|219802034 nuclear factor related to kappaB binding protein is...    37   0.060
gi|23346420 nuclear factor related to kappaB binding protein iso...    37   0.060
gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens]    37   0.060
gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]    37   0.060
gi|91982772 mucin 17 [Homo sapiens]                                    36   0.10 
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     35   0.13 
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo...    35   0.23 
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ...    35   0.23 
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ...    35   0.23 
gi|148612857 sickle tail isoform 3 [Homo sapiens]                      35   0.23 
gi|148612813 sickle tail isoform 2 [Homo sapiens]                      35   0.23 
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          34   0.30 
gi|164419758 bromodomain containing 2 [Homo sapiens]                   34   0.39 
gi|4826806 bromodomain containing 2 [Homo sapiens]                     34   0.39 
gi|118572603 ubinuclein 1 [Homo sapiens]                               33   0.51 
gi|118572601 ubinuclein 1 [Homo sapiens]                               33   0.51 
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    33   0.51 
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         33   0.51 
gi|210032580 SET domain containing 1B [Homo sapiens]                   33   0.51 
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       33   0.51 
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        33   0.66 
gi|20270323 zinc finger protein 653 [Homo sapiens]                     33   0.66 
gi|191252814 RIMS binding protein 3B [Homo sapiens]                    33   0.87 
gi|191252806 RIMS binding protein 3C [Homo sapiens]                    33   0.87 
gi|149944516 tet oncogene family member 3 [Homo sapiens]               33   0.87 
gi|148806881 hypothetical protein LOC57608 [Homo sapiens]              33   0.87 

>gi|40018638 C2 calcium-dependent domain containing 2 isoform 2
           [Homo sapiens]
          Length = 541

 Score = 1061 bits (2744), Expect = 0.0
 Identities = 541/541 (100%), Positives = 541/541 (100%)

Query: 1   MRLSPFHLQLEFHMKEKREDLQISWSFISVPEMAVNIQPKALGEDQVAETSAMSDVLKDI 60
           MRLSPFHLQLEFHMKEKREDLQISWSFISVPEMAVNIQPKALGEDQVAETSAMSDVLKDI
Sbjct: 1   MRLSPFHLQLEFHMKEKREDLQISWSFISVPEMAVNIQPKALGEDQVAETSAMSDVLKDI 60

Query: 61  LKHLAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHELKLLVRNIHVLLL 120
           LKHLAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHELKLLVRNIHVLLL
Sbjct: 61  LKHLAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHELKLLVRNIHVLLL 120

Query: 121 SEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISEAG 180
           SEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISEAG
Sbjct: 121 SEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISEAG 180

Query: 181 RSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPI 240
           RSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPI
Sbjct: 181 RSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPI 240

Query: 241 PPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKD 300
           PPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKD
Sbjct: 241 PPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKD 300

Query: 301 ISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIII 360
           ISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIII
Sbjct: 301 ISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIII 360

Query: 361 SGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQ 420
           SGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQ
Sbjct: 361 SGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQ 420

Query: 421 EDELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGTAKKHKGGILRKGAKLFF 480
           EDELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGTAKKHKGGILRKGAKLFF
Sbjct: 421 EDELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGTAKKHKGGILRKGAKLFF 480

Query: 481 RRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKKLLSRHRNKNTMNGAPVEPC 540
           RRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKKLLSRHRNKNTMNGAPVEPC
Sbjct: 481 RRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKKLLSRHRNKNTMNGAPVEPC 540

Query: 541 T 541
           T
Sbjct: 541 T 541


>gi|119226222 C2 calcium-dependent domain containing 2 isoform 1
           [Homo sapiens]
          Length = 696

 Score = 1061 bits (2744), Expect = 0.0
 Identities = 541/541 (100%), Positives = 541/541 (100%)

Query: 1   MRLSPFHLQLEFHMKEKREDLQISWSFISVPEMAVNIQPKALGEDQVAETSAMSDVLKDI 60
           MRLSPFHLQLEFHMKEKREDLQISWSFISVPEMAVNIQPKALGEDQVAETSAMSDVLKDI
Sbjct: 156 MRLSPFHLQLEFHMKEKREDLQISWSFISVPEMAVNIQPKALGEDQVAETSAMSDVLKDI 215

Query: 61  LKHLAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHELKLLVRNIHVLLL 120
           LKHLAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHELKLLVRNIHVLLL
Sbjct: 216 LKHLAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHELKLLVRNIHVLLL 275

Query: 121 SEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISEAG 180
           SEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISEAG
Sbjct: 276 SEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISEAG 335

Query: 181 RSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPI 240
           RSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPI
Sbjct: 336 RSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPI 395

Query: 241 PPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKD 300
           PPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKD
Sbjct: 396 PPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKD 455

Query: 301 ISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIII 360
           ISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIII
Sbjct: 456 ISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIII 515

Query: 361 SGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQ 420
           SGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQ
Sbjct: 516 SGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQ 575

Query: 421 EDELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGTAKKHKGGILRKGAKLFF 480
           EDELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGTAKKHKGGILRKGAKLFF
Sbjct: 576 EDELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGTAKKHKGGILRKGAKLFF 635

Query: 481 RRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKKLLSRHRNKNTMNGAPVEPC 540
           RRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKKLLSRHRNKNTMNGAPVEPC
Sbjct: 636 RRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKKLLSRHRNKNTMNGAPVEPC 695

Query: 541 T 541
           T
Sbjct: 696 T 696


>gi|42716277 transmembrane protein 24 [Homo sapiens]
          Length = 707

 Score =  225 bits (573), Expect = 9e-59
 Identities = 180/553 (32%), Positives = 276/553 (49%), Gaps = 62/553 (11%)

Query: 9   QLEFHMKE-KREDLQISWSFISVPEMAVNIQPKAL----GEDQVAETSAMSDVLKDILKH 63
           QLE +++E   E L ISW+F   P++++ + PK      GE+QV E S + +++KD    
Sbjct: 190 QLEVNLEEIPGEGLLISWAFTDRPDLSLTVLPKLQARERGEEQV-ELSTIEELIKD---- 244

Query: 64  LAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHEL-----KLLVRNIHVL 118
                    ++ T+P  +   +             PP  P+A        +L +R +   
Sbjct: 245 --------AIVSTQPAMMVNLRACSAPGGLVPSEKPPMMPQAQPAIPRPNRLFLRQLRAS 296

Query: 119 LLSEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISE 178
            L      G     CV +L++P+Q+  +   +   ++ W E+   +L  +S+EL L++  
Sbjct: 297 HLGNE-LEGTEELCCVAELDNPMQQKWTKPARAGSEVEWTEDLALDLGPQSRELTLKVLR 355

Query: 179 AGRSSEG-LLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYME--PGEL 235
           +    +  LL  AT+P+    +  S  Q   LT G         ++  E  Y E  P  L
Sbjct: 356 SSSCGDTELLGQATLPVGSPSRPLSRRQLCPLTPGPGKALGPAATMAVELHYEEGSPRNL 415

Query: 236 ----KSWPIPPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTP 291
                S P P   P  KIE DRT+MP GT+VTTVT V+++PR+D G+      DSP ++P
Sbjct: 416 GTPTSSTPRPSITPTKKIELDRTIMPDGTIVTTVTTVQSRPRID-GKL-----DSPSRSP 469

Query: 292 IKVKVIEKDISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSE-SSKLKLK 350
            KV+V EK  +V  ++  S P + + SSS  +  + NG DPVAE AIRQL+E S ++  K
Sbjct: 470 SKVEVTEKTTTV--LSESSGPSNTSHSSSPGDSHLSNGLDPVAETAIRQLTEPSGRVAKK 527

Query: 351 SPRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDA-----PSHP--ERAAASA 403
           +P K+ST+IISG+SK  ++QD + AL  GY AS++++ Q+DA     PS P  +  A S 
Sbjct: 528 TPTKRSTLIISGVSKVPIAQD-ELALSLGYAASLEASVQDDAGTSGGPSSPPSDPPAMSP 586

Query: 404 PPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGT 463
            P +A S+  S+    + DE    D+ + P             D  E    S   LE  +
Sbjct: 587 GPLDALSSPTSVQ---EADETTRSDISERPSV-----------DDIESETGSTGALETRS 632

Query: 464 AKKHKGGILRKGAKLFFRRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKKLL 523
            K HK   LR G KL FRRR +QK+ G+SQSH+DL         R+K  + +R L K+  
Sbjct: 633 LKDHKVSFLRSGTKLIFRRRPRQKEAGLSQSHDDLSNATATPSVRKKAGSFSRRLIKRFS 692

Query: 524 SRHRNKNTMNGAP 536
            + + K   N +P
Sbjct: 693 FKSKPKANGNPSP 705


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 81/361 (22%), Positives = 143/361 (39%), Gaps = 36/361 (9%)

Query: 159 EEFTFELNAKSKELHLQISEAGRSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSS 218
           E+ TF  N  +++   ++ +AG      + T++          S   S + +S S+  SS
Sbjct: 120 EKLTF--NNPTEDFRRKLLKAGGDPNRSIHTSS------SSSSSSSSSSSSSSSSSSSSS 171

Query: 219 VLGSVTAEFSYMEPGELKSWPIPPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGR 278
              S ++  S        S     P    K+ K+    P        +A K +P  D  +
Sbjct: 172 SSSSSSSSSSSSSSSSSSSTSFSKP---HKLMKEHKEKPSKDSREHKSAFK-EPSRDHNK 227

Query: 279 ASPLSSDSPVKT-PIKVKVIEKDISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVA 337
           +S  SS  P +  P+K + I   ++ +       P+SK        L + +G D  A   
Sbjct: 228 SSKESSKKPKENKPLKEEKIVPKMAFK----EPKPMSKEPKPDSNLLTITSGQDKKAPSK 283

Query: 338 IRQLSESSKLKLKSPRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPE 397
              +S+S +L  K  RKKS       S  +L +   +A     T S D    +D  SH +
Sbjct: 284 RPPISDSEELSAKK-RKKS-------SSEALFKSFSSAPPLILTCSADKKQIKD-KSHVK 334

Query: 398 RAAASAPPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMS 457
                   E +E  +++L P     + +  D+E+   + + S Q    P     S SS S
Sbjct: 335 MGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQ----PSPASSSSSSSS 390

Query: 458 VLEPGTAKKHKGGILRKGAKLFFRRRHQQKDPGMSQSHNDLVFLEQP---EGSRRKGITL 514
              P   ++   G LR   K      ++++   +  + ND   +E+P    GSR + ++L
Sbjct: 391 SFTPSQTRQQ--GPLRSIMKDLHSDDNEEESDEVEDNDNDSE-MERPVNRGGSRSRRVSL 447

Query: 515 T 515
           +
Sbjct: 448 S 448


>gi|219802034 nuclear factor related to kappaB binding protein
           isoform 1 [Homo sapiens]
          Length = 1299

 Score = 36.6 bits (83), Expect = 0.060
 Identities = 56/239 (23%), Positives = 97/239 (40%), Gaps = 14/239 (5%)

Query: 88  QCAASTAQESCPPKPPRAHELKLLVRNIHVLLLSE-PGASGHINAVCVVQLNDPVQRFSS 146
           Q AA+ A+++   KP    ++K   +   + +LS  P     ++         PV    +
Sbjct: 666 QAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSGPSEQSQMSLSDSSMPPTPV----T 721

Query: 147 TLTKNTPDLMWEEEFTFELNAKSKELHLQISEAGRSSEGLLATATVPLDLFKKQPSGPQS 206
            +T  TP L         ++A +K     +SE  +SS G+L  ++  +       S   S
Sbjct: 722 PVTPTTPALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHLGTMLSPASS 781

Query: 207 FTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPIPPPVPAAKIEKDRTV--MPCG---TV 261
            T  S  A    V  S +A  S +    + + P  P VP       +T+  MP G    V
Sbjct: 782 QTAPSSQAAARVVSHSGSAGLSQV---RVVAQPSLPAVPQQSGGPAQTLPQMPAGPQIRV 838

Query: 262 VTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKDISVQAIACRSAPVSKTLSSS 320
             T T  K  P+  V    P+ + +   T  +    +  ++V ++   ++PVSK  +SS
Sbjct: 839 PATATQTKVVPQT-VMATVPVKAQTTAATVQRPGPGQTGLTVTSLPATASPVSKPATSS 896


>gi|23346420 nuclear factor related to kappaB binding protein
           isoform 2 [Homo sapiens]
          Length = 1324

 Score = 36.6 bits (83), Expect = 0.060
 Identities = 56/239 (23%), Positives = 97/239 (40%), Gaps = 14/239 (5%)

Query: 88  QCAASTAQESCPPKPPRAHELKLLVRNIHVLLLSE-PGASGHINAVCVVQLNDPVQRFSS 146
           Q AA+ A+++   KP    ++K   +   + +LS  P     ++         PV    +
Sbjct: 691 QAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSGPSEQSQMSLSDSSMPPTPV----T 746

Query: 147 TLTKNTPDLMWEEEFTFELNAKSKELHLQISEAGRSSEGLLATATVPLDLFKKQPSGPQS 206
            +T  TP L         ++A +K     +SE  +SS G+L  ++  +       S   S
Sbjct: 747 PVTPTTPALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHLGTMLSPASS 806

Query: 207 FTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPIPPPVPAAKIEKDRTV--MPCG---TV 261
            T  S  A    V  S +A  S +    + + P  P VP       +T+  MP G    V
Sbjct: 807 QTAPSSQAAARVVSHSGSAGLSQV---RVVAQPSLPAVPQQSGGPAQTLPQMPAGPQIRV 863

Query: 262 VTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKDISVQAIACRSAPVSKTLSSS 320
             T T  K  P+  V    P+ + +   T  +    +  ++V ++   ++PVSK  +SS
Sbjct: 864 PATATQTKVVPQT-VMATVPVKAQTTAATVQRPGPGQTGLTVTSLPATASPVSKPATSS 921


>gi|40288199 hypothetical protein LOC219287 isoform 2 [Homo sapiens]
          Length = 552

 Score = 36.6 bits (83), Expect = 0.060
 Identities = 43/158 (27%), Positives = 64/158 (40%), Gaps = 26/158 (16%)

Query: 388 HQEDAPSHPERAAASAPPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWSSQVL---- 443
           H ++ P HPE+      P   E    S  P P+ED   S      P+  ++S   L    
Sbjct: 382 HPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPR-DSYSGDALYDLY 440

Query: 444 LDPDG---------DELSESSMSVLEPG-----TAKKHKGGILRKGAKLFFRRRHQQKDP 489
            DPDG         D    SS+S L+P      T      G L K +K+    +H    P
Sbjct: 441 ADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLTNLP 500

Query: 490 GMSQSHNDLVFLEQPEGSR--RKGITLTRILNKKLLSR 525
               SH   V  +QP  S   R  I ++++L +++ +R
Sbjct: 501 ---SSHP--VVHQQPSRSEMPRTKIPVSKVLVRRVSNR 533


>gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]
          Length = 671

 Score = 36.6 bits (83), Expect = 0.060
 Identities = 43/158 (27%), Positives = 64/158 (40%), Gaps = 26/158 (16%)

Query: 388 HQEDAPSHPERAAASAPPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWSSQVL---- 443
           H ++ P HPE+      P   E    S  P P+ED   S      P+  ++S   L    
Sbjct: 501 HPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPR-DSYSGDALYDLY 559

Query: 444 LDPDG---------DELSESSMSVLEPG-----TAKKHKGGILRKGAKLFFRRRHQQKDP 489
            DPDG         D    SS+S L+P      T      G L K +K+    +H    P
Sbjct: 560 ADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLTNLP 619

Query: 490 GMSQSHNDLVFLEQPEGSR--RKGITLTRILNKKLLSR 525
               SH   V  +QP  S   R  I ++++L +++ +R
Sbjct: 620 ---SSHP--VVHQQPSRSEMPRTKIPVSKVLVRRVSNR 652


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 60/284 (21%), Positives = 107/284 (37%), Gaps = 40/284 (14%)

Query: 183  SEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPIPP 242
            SEG     ++P+       + P++ TL++     +S + + T   S   P E  S PI  
Sbjct: 3042 SEGSTPLTSIPVST--TPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIST 3099

Query: 243  ----------------PVPAAKIEK-DRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSD 285
                            PV ++ I     T +   T VTT T   + P    G + P S+ 
Sbjct: 3100 YSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTP 3159

Query: 286  SPVKTPIKVKVIEKDISVQAIACRSAPVSKTLSSS--DTELLVLNGSDPVAEVAIRQLSE 343
            S   TP+    +   + V +          TLS++  DT   V   ++  +       +E
Sbjct: 3160 SEGSTPLTYMPVSTMLVVSS-------EDSTLSATPVDTSTPVTTSTEATSSTT----AE 3208

Query: 344  SSKLKLKSPRKKSTIIIS-GISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAAS 402
             + +   +P +  T + S  +S T ++    + L    T  VDS    + P      A+S
Sbjct: 3209 GTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILS---TTPVDS----NTPLTTSTEASS 3261

Query: 403  APPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWSSQVLLDP 446
            +PP    ++  +  P      L S  +     A++ +S +   P
Sbjct: 3262 SPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTP 3305



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 56/240 (23%), Positives = 94/240 (39%), Gaps = 38/240 (15%)

Query: 177  SEAGRSSEGLLATATVPLDLFKKQPSGPQS----FTLTSGSACGSSVLGSV---TAEFSY 229
            SEAG  S   + T+T P+    K  S P +        S ++ GS++L S+   T   + 
Sbjct: 2825 SEAGTLSTTPVDTST-PVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVAS 2883

Query: 230  MEPGELKSWPIPPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVK 289
             E   L + P+   +P                VTT T   + P    G + P+S+ S V 
Sbjct: 2884 SEASTLSTTPVDTSIP----------------VTTSTEGSSSPTTAEGTSMPISTPSEVS 2927

Query: 290  TPIKVKVIEKDISVQAIACRSAPVSKTLSSS--DTELLVLNGSDPVAEVAIRQLSESSKL 347
            TP+        I V  +    +  S TLS++  DT   V   ++  +       +E + +
Sbjct: 2928 TPL------TSILVSTVPVAGSEAS-TLSTTPVDTRTPVTTSAEASSSPT---TAEGTSM 2977

Query: 348  KLKSPRKKSTIIISGISKTSLSQDHDAALMQGYTA--SVDSTHQEDAPSHPERAAASAPP 405
             + +P ++ T + S    T      +A+ +    A  S   T   +A S P  A  +  P
Sbjct: 2978 PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIP 3037



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 87/405 (21%), Positives = 141/405 (34%), Gaps = 58/405 (14%)

Query: 29  SVPEMAVNIQPKALGEDQVAETSAMSDVLKDILKHLAGSASPSVVLITKPTTVKEAQNLQ 88
           S P   VN  P +   +     ++MS     +    A + S + V  + P T     +  
Sbjct: 492 SPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEAS-- 549

Query: 89  CAASTAQE--SCPPKPPRAHELKLLVRNIHVLLL--SEPGASGHINAVCVVQLNDPVQRF 144
            ++ST  E  S P   P      L    +   L+  SE   +    A     +    +  
Sbjct: 550 -SSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEAS 608

Query: 145 SSTLTK---NTPDLMWEEEFTFELNAKSKELHLQISEAGRSSEGLLATATVPLDLFKKQP 201
           SS+ T    + P   + E  T   +       +  SEA   S       T P+D      
Sbjct: 609 SSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLS-------TTPVD------ 655

Query: 202 SGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGE-LKSWPIPPPVPAAKIEKDRTVMPC-- 258
           S     T T  ++  ++  G+     +Y E    L S P+   + A+      +  P   
Sbjct: 656 SNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDT 715

Query: 259 GTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKDISVQAIACRSAPVSKT-L 317
            T VTT T   + P    G + P S+ S   TP+                 S PVSKT L
Sbjct: 716 STPVTTSTEASSSPTTADGASMPTSTPSEGSTPL----------------TSMPVSKTLL 759

Query: 318 SSSDTELLVLNGSDPVAEVAIR-------QLSESSKLKLKSPRKKSTIIIS-GISKTSLS 369
           +SS+   L     D    +            +E + + + +P + S ++ S  +S T ++
Sbjct: 760 TSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVT 819

Query: 370 QDHDAALMQGYTASVDS----THQEDAPSHPERAAASAPPEEAES 410
               + L    T  VDS    T   +  S P  A  ++ P    S
Sbjct: 820 SPEASTLS---TTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYS 861



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 75/361 (20%), Positives = 122/361 (33%), Gaps = 42/361 (11%)

Query: 48   AETSAMSDVLKDILKHLAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHE 107
            +E S +S    D   H+  S   S      PTT    +      ST  E  P        
Sbjct: 762  SEASTLSTTPLDTSTHITTSTEASC----SPTTT---EGTSMPISTPSEGSP-------- 806

Query: 108  LKLLVRNIHVLLLSEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNA 167
               L+ +I V +           +   V  N PV   +   +  TP        +     
Sbjct: 807  ---LLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEG 863

Query: 168  KSKELHLQISEAGRSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEF 227
            ++    + +S    ++  +   +T P+D          S  +T+ +   SS   S     
Sbjct: 864  RTPLTSMPVSTTLVATSAISTLSTTPVDT---------STPVTNSTEARSSPTTSEGTSM 914

Query: 228  SYMEPGE----LKSWP--IPPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASP 281
                PGE    L S P    P V +       T +   T VTT T   + P    G + P
Sbjct: 915  PTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 974

Query: 282  LSSDSPVKTPIKVKVIEKDI--SVQAIACRSAPV-SKTLSSSDTELLVLNGSDPVAE--- 335
             S+ S   TP+    +   +  + +A    + PV S T  ++ TE    +   P AE   
Sbjct: 975  TSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTE---ASSPPPTAEGTS 1031

Query: 336  VAIRQLSESSKLKLKSPRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSH 395
            +     SE S    + P   + +  S  S  S +    +  +  Y+ +  S+   D  S 
Sbjct: 1032 MPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSM 1091

Query: 396  P 396
            P
Sbjct: 1092 P 1092



 Score = 32.7 bits (73), Expect = 0.87
 Identities = 42/210 (20%), Positives = 85/210 (40%), Gaps = 20/210 (9%)

Query: 260  TVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKDISVQAIACRSAPVSKTLSS 319
            T+VTT T   + P    G + P S+     TP+   ++   +   + A        TLS+
Sbjct: 2662 TLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEA-------STLST 2714

Query: 320  S--DTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKTSLSQDHDAALM 377
            +  DT   V   ++  +       +E + +++ +P   ST + S +  T      +A+ +
Sbjct: 2715 TPVDTSTPVTTSAEASSSPT---TAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTV 2771

Query: 378  QGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQEDELDSWDLEKEPQAAA 437
               T +VD++     P      A+S+P     ++  +  P      L S  +   P A++
Sbjct: 2772 S--TTAVDTS----IPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASS 2825

Query: 438  WSSQVLLDP--DGDELSESSMSVLEPGTAK 465
             +  +   P      ++ S+ +   P TA+
Sbjct: 2826 EAGTLSTTPVDTSTPVTTSTKASSSPTTAE 2855



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 78/355 (21%), Positives = 124/355 (34%), Gaps = 41/355 (11%)

Query: 138  NDPVQRFSST-LTKNTPDLMWEEEFTFELNAKSKELHLQISEAGRSSEGLLATATVPLDL 196
            N  V   S+T +  NTP     E  +    A+   +    S  G +    +  +T  +  
Sbjct: 2293 NSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVAS 2352

Query: 197  FKKQP----SGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPIP---------PP 243
            F+           S  +T+ S  GSS     TA+ + M          P         P 
Sbjct: 2353 FETSTLSTTPADTSTPVTTYSQAGSS---PTTADDTSMPTSTYSEGSTPLTSVPVSTMPV 2409

Query: 244  VPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKD--I 301
            V +       T +   T VTT T   + P    G + P S  S   TP+    +     +
Sbjct: 2410 VSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVV 2469

Query: 302  SVQAIACRSAPV-SKTLSSSDTELLVLNGSDPVAE---VAIRQLSESSKLKLKSPRKKST 357
            S +A    + PV + T  ++ TE    + S   AE   V I   SE S L    P   + 
Sbjct: 2470 SSEAGTLSTTPVDTSTPMTTSTE---ASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTP 2526

Query: 358  II---ISGISKTSLSQDHDAALMQGYTASVDSTHQEDAP-------SHPERAAASAPPEE 407
            +     S +S T +  +         ++S  S      P       S P R+   +    
Sbjct: 2527 VASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586

Query: 408  AESAQASLAPKPQEDEL---DSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVL 459
            A S  ++L+  P +  +    S +    P  A  +S  +  P   E+S S  S+L
Sbjct: 2587 ASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTP--SEVSTSLTSIL 2639



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 52/245 (21%), Positives = 89/245 (36%), Gaps = 24/245 (9%)

Query: 188  ATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPIPPPVPAA 247
            A  + P+  + +  S P         A G+S+  S  +E S   P    S+   P V + 
Sbjct: 3306 ADTSTPVTTYSQASSSPPI-------ADGTSMPTSTYSEGS--TPLTNMSFSTTPVVSSE 3356

Query: 248  KIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKD--ISVQA 305
                  T +   T VTT T     P    G + P SS S   TP+    +     +S + 
Sbjct: 3357 ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEV 3416

Query: 306  IACRSAPV-SKTLSSSDTE------------LLVLNGSDPVAEVAIRQLSESSKLKLKSP 352
                + PV S TL ++ TE            L     S+    ++I  LS +     ++ 
Sbjct: 3417 NTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAS 3476

Query: 353  RKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQ 412
               +T + +    T+ S  + +      T+   ST  E +        ++ P   +E++ 
Sbjct: 3477 TLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEAST 3536

Query: 413  ASLAP 417
             S  P
Sbjct: 3537 LSTTP 3541



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 50/243 (20%), Positives = 90/243 (37%), Gaps = 21/243 (8%)

Query: 174 LQISEAGRSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPG 233
           + +S+   +S      +T PLD            T ++ ++C  +     +   S    G
Sbjct: 752 MPVSKTLLTSSEASTLSTTPLDT-------STHITTSTEASCSPTTTEGTSMPISTPSEG 804

Query: 234 E--LKSWPIP-PPVPAAKIEK-DRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVK 289
              L S P+   PV + +      T +   + VTT T V + P    G + P S+ S  +
Sbjct: 805 SPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGR 864

Query: 290 TPIKVKVIEKDISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKL 349
           TP+    +        +   SA  + + +  DT   V N ++  +       SE + +  
Sbjct: 865 TPLTSMPVS-----TTLVATSAISTLSTTPVDTSTPVTNSTEARSSPT---TSEGTSMPT 916

Query: 350 KSPRKKSTIIISGISKTSLSQDHDAALMQG--YTASVDSTHQEDAPSHPERAAASAPPEE 407
            +P + ST + S    T+     +A  +       S   T   +A S P  A  ++ P  
Sbjct: 917 STPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTS 976

Query: 408 AES 410
             S
Sbjct: 977 TPS 979



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 50/219 (22%), Positives = 87/219 (39%), Gaps = 25/219 (11%)

Query: 208  TLTSGSACGSSVLGSVTAEFSYMEPGE-LKSWPIPPPVPAAKIEKDRTVMPCGTV--VTT 264
            T +  S+  ++  G+     +Y E    L S P+   +  +      +  P  T   VTT
Sbjct: 1075 TYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTT 1134

Query: 265  VTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKD--ISVQAIACRSAPV-SKTLSSSD 321
             T   + P    G + P S  S   TP+    +     +S +A    + PV SKT  ++ 
Sbjct: 1135 STEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATS 1194

Query: 322  TELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIIS-GISKTSLSQDHDAALMQGY 380
            TE    +   P AEV        + +   +P ++ST + S  +  T ++    + L    
Sbjct: 1195 TE---ASSPPPTAEV--------TSMPTSTPGERSTPLTSMPVRHTPVASSEASTLS--- 1240

Query: 381  TASVDS----THQEDAPSHPERAAASAPPEEAESAQASL 415
            T+ VD+    T   +  S P  A  ++ P    S  ++L
Sbjct: 1241 TSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTL 1279


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 50/205 (24%), Positives = 80/205 (39%), Gaps = 14/205 (6%)

Query: 269 KTKPRVDVGRASPLSSDSPVK----TPIKVKVIEKDISVQAIACRSAPVSKTLSSSDTEL 324
           K K  V     SP  + SPVK    TP K K   K+ +      +S   +KTL     E 
Sbjct: 707 KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE- 765

Query: 325 LVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKTSLSQDHDAALMQ-GYTAS 383
                  P  E A R  ++    K KSP K+  +     +K+ L +D  A   +      
Sbjct: 766 ----AKTPAKEEA-RSPADKFPEKAKSPVKEE-VKSPEKAKSPLKEDAKAPEKEIPKKEE 819

Query: 384 VDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWSSQVL 443
           V S  +E+    P+      PP++AE  +A   PK +E +    +   + +A     +  
Sbjct: 820 VKSPVKEE--EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 877

Query: 444 LDPDGDELSESSMSVLEPGTAKKHK 468
            +P  ++  ES +   +     K K
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKK 902



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 41/193 (21%), Positives = 67/193 (34%), Gaps = 19/193 (9%)

Query: 269 KTKPRVDVGRASPLSSDSPVKTPIKVKVIEKDISVQAIACRSAPVSKTLSSSDTELLVLN 328
           K K  V     SP  + SPVK   K     K           +PV +   S +       
Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK-----------SPVKEEAKSPE------K 707

Query: 329 GSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTH 388
              PV E A  +  E +K  +K   K      S + + + S +   +  +  T  V S  
Sbjct: 708 AKSPVKEEA--KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE 765

Query: 389 QEDAPSHPERAAASAPPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWSSQVLLDPDG 448
            +       R+ A   PE+A+S        P++ +    +  K P+      + +  P  
Sbjct: 766 AKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825

Query: 449 DELSESSMSVLEP 461
           +E     + V EP
Sbjct: 826 EEEKPQEVKVKEP 838


>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
            sapiens]
          Length = 1198

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 39/315 (12%)

Query: 242  PPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRAS-PLSSDSPVKTPIKVKVIEKD 300
            PP P A   KD  V PC        A    P  D+     PL    P+ T   +  I++ 
Sbjct: 753  PPGPDAPPSKD--VPPCQE---PPPAQDLSPCQDLPAGQEPLPHQDPLLTK-DLPAIQES 806

Query: 301  ISVQAIACRSAPVSK-----------TLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKL 349
             +     C+  P S+           T+SS D  LL   G  P A    R      +++L
Sbjct: 807  PTRDLPPCQDLPPSQVSLPAKALTEDTMSSGD--LLAATGDPPAAP---RPAFVIPEVRL 861

Query: 350  KSPRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAA--SAPPEE 407
             S   +      G S      +    + +G     D        ++ ER+ A  S+  E 
Sbjct: 862  DSTYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIET 921

Query: 408  AESAQASLAPKPQED----ELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGT 463
             + A+  L+ + Q            L +EP+   ++S   L     E + S+  +  P T
Sbjct: 922  GQGAEGGLSLRVQNSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPST 981

Query: 464  AKKHKG--GILRKGAKLFFRRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKK 521
             KK  G  G       LFF    +        S  D V  +     +RK   L + +  K
Sbjct: 982  LKKELGRNGGSMHHLSLFFTGHRK-------MSGADTVGDDDEASRKRKSKNLAKDMKNK 1034

Query: 522  LLSRHRNKNTMNGAP 536
             L   R +N   GAP
Sbjct: 1035 -LGIFRRRNESPGAP 1048


>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
           sapiens]
          Length = 519

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 39/315 (12%)

Query: 242 PPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRAS-PLSSDSPVKTPIKVKVIEKD 300
           PP P A   KD  V PC        A    P  D+     PL    P+ T   +  I++ 
Sbjct: 74  PPGPDAPPSKD--VPPCQE---PPPAQDLSPCQDLPAGQEPLPHQDPLLTK-DLPAIQES 127

Query: 301 ISVQAIACRSAPVSK-----------TLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKL 349
            +     C+  P S+           T+SS D  LL   G  P A    R      +++L
Sbjct: 128 PTRDLPPCQDLPPSQVSLPAKALTEDTMSSGD--LLAATGDPPAAP---RPAFVIPEVRL 182

Query: 350 KSPRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAA--SAPPEE 407
            S   +      G S      +    + +G     D        ++ ER+ A  S+  E 
Sbjct: 183 DSTYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIET 242

Query: 408 AESAQASLAPKPQED----ELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGT 463
            + A+  L+ + Q            L +EP+   ++S   L     E + S+  +  P T
Sbjct: 243 GQGAEGGLSLRVQNSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPST 302

Query: 464 AKKHKG--GILRKGAKLFFRRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKK 521
            KK  G  G       LFF    +        S  D V  +     +RK   L + +  K
Sbjct: 303 LKKELGRNGGSMHHLSLFFTGHRK-------MSGADTVGDDDEASRKRKSKNLAKDMKNK 355

Query: 522 LLSRHRNKNTMNGAP 536
            L   R +N   GAP
Sbjct: 356 -LGIFRRRNESPGAP 369


>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
           sapiens]
          Length = 917

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 39/315 (12%)

Query: 242 PPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRAS-PLSSDSPVKTPIKVKVIEKD 300
           PP P A   KD  V PC        A    P  D+     PL    P+ T   +  I++ 
Sbjct: 472 PPGPDAPPSKD--VPPCQE---PPPAQDLSPCQDLPAGQEPLPHQDPLLTK-DLPAIQES 525

Query: 301 ISVQAIACRSAPVSK-----------TLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKL 349
            +     C+  P S+           T+SS D  LL   G  P A    R      +++L
Sbjct: 526 PTRDLPPCQDLPPSQVSLPAKALTEDTMSSGD--LLAATGDPPAAP---RPAFVIPEVRL 580

Query: 350 KSPRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAA--SAPPEE 407
            S   +      G S      +    + +G     D        ++ ER+ A  S+  E 
Sbjct: 581 DSTYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIET 640

Query: 408 AESAQASLAPKPQED----ELDSWDLEKEPQAAAWSSQVLLDPDGDELSESSMSVLEPGT 463
            + A+  L+ + Q            L +EP+   ++S   L     E + S+  +  P T
Sbjct: 641 GQGAEGGLSLRVQNSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPST 700

Query: 464 AKKHKG--GILRKGAKLFFRRRHQQKDPGMSQSHNDLVFLEQPEGSRRKGITLTRILNKK 521
            KK  G  G       LFF    +        S  D V  +     +RK   L + +  K
Sbjct: 701 LKKELGRNGGSMHHLSLFFTGHRK-------MSGADTVGDDDEASRKRKSKNLAKDMKNK 753

Query: 522 LLSRHRNKNTMNGAP 536
            L   R +N   GAP
Sbjct: 754 -LGIFRRRNESPGAP 767


>gi|148612857 sickle tail isoform 3 [Homo sapiens]
          Length = 1309

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 44/189 (23%), Positives = 75/189 (39%), Gaps = 19/189 (10%)

Query: 311  APVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKTSLSQ 370
            APV K   S D+         P +E  + +L   S      P ++S +  SG++ T    
Sbjct: 984  APVDKVELSEDS---------PNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGD 1034

Query: 371  DHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQEDELDSWDLE 430
                   +  TA   S   EDA   P+  A   P EE  SA    +P P        + E
Sbjct: 1035 VVYTGRKENITAKASS---EDAGPSPQTRATKYPAEEPASAWTP-SPPPVTTSSSKDEEE 1090

Query: 431  KEPQAAAWSSQVLLDPDGDELSESSMSVLEPGTAKKHKGGILRKG--AKLFFRRRHQQKD 488
            +E +      +++ +  G   +  +  +  P +AK   G + + G  +KL   R+++Q +
Sbjct: 1091 EEEE----GDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQAN 1146

Query: 489  PGMSQSHND 497
                +S  D
Sbjct: 1147 GSAKKSGGD 1155


>gi|148612813 sickle tail isoform 2 [Homo sapiens]
          Length = 1264

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 44/189 (23%), Positives = 75/189 (39%), Gaps = 19/189 (10%)

Query: 311  APVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKTSLSQ 370
            APV K   S D+         P +E  + +L   S      P ++S +  SG++ T    
Sbjct: 939  APVDKVELSEDS---------PNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGD 989

Query: 371  DHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQEDELDSWDLE 430
                   +  TA   S   EDA   P+  A   P EE  SA    +P P        + E
Sbjct: 990  VVYTGRKENITAKASS---EDAGPSPQTRATKYPAEEPASAWTP-SPPPVTTSSSKDEEE 1045

Query: 431  KEPQAAAWSSQVLLDPDGDELSESSMSVLEPGTAKKHKGGILRKG--AKLFFRRRHQQKD 488
            +E +      +++ +  G   +  +  +  P +AK   G + + G  +KL   R+++Q +
Sbjct: 1046 EEEE----GDKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQAN 1101

Query: 489  PGMSQSHND 497
                +S  D
Sbjct: 1102 GSAKKSGGD 1110


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 34.3 bits (77), Expect = 0.30
 Identities = 39/208 (18%), Positives = 80/208 (38%), Gaps = 11/208 (5%)

Query: 239 PIPPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIE 298
           P   P+P+  + K+         VT V  V+  P+V+      +  D P+KT  K  V E
Sbjct: 547 PAAKPLPSKSVRKESKEET--PEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTE 604

Query: 299 KDISVQAIACRSAPVSKTLSSSD-TELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKST 357
           K++  +      +PV   ++    T++      +   +   +   E  K + + P+K+  
Sbjct: 605 KEVPSKE---EPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKE-- 659

Query: 358 IIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAP 417
            +     KT + ++      +          +E+     +      PP+E +        
Sbjct: 660 -VAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEK 718

Query: 418 K--PQEDELDSWDLEKEPQAAAWSSQVL 443
           K   +E++    +++K P+ A  SS  L
Sbjct: 719 KEVKKEEKEPKKEIKKLPKDAKKSSTPL 746


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 33.9 bits (76), Expect = 0.39
 Identities = 43/170 (25%), Positives = 66/170 (38%), Gaps = 16/170 (9%)

Query: 352 PRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESA 411
           P+++  ++++ I K S  +    A +QG   SV S HQ  A S     A   PP E  + 
Sbjct: 181 PQEEQELVVT-IPKNSHKKGAKLAALQG---SVTSAHQVPAVSSVSHTALYTPPPEIPTT 236

Query: 412 -----QASLAPKPQEDELDSWDLEKEPQAAAWSSQVLLDPDG-----DELSESSMSVLEP 461
                  S+   P    L S         AA  +Q L    G     D  + +  ++L P
Sbjct: 237 VLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAP 296

Query: 462 GTAKKHKGGILRKGAKLFFRRRHQQKDPGMSQSHNDLVFLEQPEGSRRKG 511
           G+     G +  K A+L   RR   +   +     DL   +Q   S +KG
Sbjct: 297 GSPASPPGSLEPKAARLPPMRRESGRP--IKPPRKDLPDSQQQHQSSKKG 344


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 33.9 bits (76), Expect = 0.39
 Identities = 43/170 (25%), Positives = 66/170 (38%), Gaps = 16/170 (9%)

Query: 352 PRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESA 411
           P+++  ++++ I K S  +    A +QG   SV S HQ  A S     A   PP E  + 
Sbjct: 181 PQEEQELVVT-IPKNSHKKGAKLAALQG---SVTSAHQVPAVSSVSHTALYTPPPEIPTT 236

Query: 412 -----QASLAPKPQEDELDSWDLEKEPQAAAWSSQVLLDPDG-----DELSESSMSVLEP 461
                  S+   P    L S         AA  +Q L    G     D  + +  ++L P
Sbjct: 237 VLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAP 296

Query: 462 GTAKKHKGGILRKGAKLFFRRRHQQKDPGMSQSHNDLVFLEQPEGSRRKG 511
           G+     G +  K A+L   RR   +   +     DL   +Q   S +KG
Sbjct: 297 GSPASPPGSLEPKAARLPPMRRESGRP--IKPPRKDLPDSQQQHQSSKKG 344


>gi|118572603 ubinuclein 1 [Homo sapiens]
          Length = 1134

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 39/153 (25%), Positives = 61/153 (39%), Gaps = 16/153 (10%)

Query: 399 AAASAPPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWS-SQVLLDPDGDELSESSMS 457
           A++   P +A    A+  P   ED LD  DL + P ++  + S+ L   +      S  +
Sbjct: 636 ASSRELPSQASGGLANPPPVNLEDSLDE-DLIRNPASSVEAVSKELAALNSRAAGNSEFT 694

Query: 458 VLEPGTAKKHK-GGILRKGAKLFFRRRHQQKDPGMSQSHNDLVFL-------------EQ 503
           +  P  A   K GG+L    K  F +      P  S   + L FL             ++
Sbjct: 695 LPAPSKAPAEKVGGVLCTEEKRNFAKPSPSAPPPASSLQSPLNFLAEQALALGQSSQEKK 754

Query: 504 PEGSRRKGITLTRILNKKLLSRHRNKNTMNGAP 536
           PE S  K ++    LNK L   H++K   +  P
Sbjct: 755 PESSGYKELSCQAPLNKGLPEVHQSKAKHHSLP 787


>gi|118572601 ubinuclein 1 [Homo sapiens]
          Length = 1134

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 39/153 (25%), Positives = 61/153 (39%), Gaps = 16/153 (10%)

Query: 399 AAASAPPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWS-SQVLLDPDGDELSESSMS 457
           A++   P +A    A+  P   ED LD  DL + P ++  + S+ L   +      S  +
Sbjct: 636 ASSRELPSQASGGLANPPPVNLEDSLDE-DLIRNPASSVEAVSKELAALNSRAAGNSEFT 694

Query: 458 VLEPGTAKKHK-GGILRKGAKLFFRRRHQQKDPGMSQSHNDLVFL-------------EQ 503
           +  P  A   K GG+L    K  F +      P  S   + L FL             ++
Sbjct: 695 LPAPSKAPAEKVGGVLCTEEKRNFAKPSPSAPPPASSLQSPLNFLAEQALALGQSSQEKK 754

Query: 504 PEGSRRKGITLTRILNKKLLSRHRNKNTMNGAP 536
           PE S  K ++    LNK L   H++K   +  P
Sbjct: 755 PESSGYKELSCQAPLNKGLPEVHQSKAKHHSLP 787


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 41/198 (20%), Positives = 80/198 (40%), Gaps = 34/198 (17%)

Query: 242 PPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKDI 301
           PP   A +   R  +P G         K   +     +S  SSD   +   K + ++K +
Sbjct: 100 PPAKKAAVPAKRVGLPPG---------KAAAKASESSSSEESSDDDDEEDQKKQPVQKGV 150

Query: 302 SVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTI--- 358
             QA A ++ P  K   SSD++    +  +P      +    + K + K+P K +     
Sbjct: 151 KPQAKAAKAPP--KKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPK 208

Query: 359 IISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERA-------------AASAPP 405
           I +G + +S S           ++S D + +E A + P++              AA+ P 
Sbjct: 209 IANGKAASSSSSSSS-------SSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPT 261

Query: 406 EEAESAQASLAPKPQEDE 423
            ++ S++ S + + +E +
Sbjct: 262 RKSSSSEDSSSDEEEEQK 279



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 56/221 (25%), Positives = 81/221 (36%), Gaps = 28/221 (12%)

Query: 278 RASPLSSDSPVKTPIKVKVIEKDISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVA 337
           +  P SS  P   P   K +      +A+  +  PV  +  SSD        SD  +E  
Sbjct: 285 KPGPYSSVPPPSAPPPKKSLGTQPPKKAVE-KQQPVESSEDSSDE-------SDSSSEEE 336

Query: 338 IRQLSES--SKLKLKSP-RKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPS 394
            +  +++  SK   K P  KK+    S  S +  S+D +A      T    S        
Sbjct: 337 KKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTK 396

Query: 395 HPERAAASAPPEEAESAQASLAPK----PQEDELDSWDLEK--------EPQA---AAWS 439
            P    A+AP +     Q  L  K      E+E  S + EK        +P+A   AA S
Sbjct: 397 SPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALS 456

Query: 440 SQVLLDPDG--DELSESSMSVLEPGTAKKHKGGILRKGAKL 478
                 P G  D  S+S  S  E    K  K  + +K  K+
Sbjct: 457 LPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKV 497


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 49/212 (23%), Positives = 79/212 (37%), Gaps = 29/212 (13%)

Query: 242  PPVPAAKIEKDRTVMPCGTV---VTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIE 298
            PPV   + EK   V P G         TA KT+  + V  +       PV    K + IE
Sbjct: 1926 PPVSPGRTEKRLPVSPSGRTDKHQPVSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIE 1985

Query: 299  KDISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTI 358
            + +SV+ +  ++    +  S   T L            + +Q     K K++  ++K  I
Sbjct: 1986 ETMSVREL-MKAFQSGQDPSKHKTGLF--------EHKSAKQKQPQEKGKVRVEKEKGPI 2036

Query: 359  IISGISKTSLSQ----------DHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPE-- 406
            +    ++ + +Q             A   +G   S     +EDA    E+  +   PE  
Sbjct: 2037 LTQREAQKTENQTIKRGQRLPVTGTAESKRGVRVSSIGVKKEDAAGGKEKVLSHKIPEPV 2096

Query: 407  ----EAESAQASLAPKPQ-EDELDSWDLEKEP 433
                E ES + S  PK +  DE    DL+  P
Sbjct: 2097 QSVPEEESHRESEVPKEKMADEQGDMDLQISP 2128


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 33/132 (25%), Positives = 53/132 (40%), Gaps = 5/132 (3%)

Query: 222 SVTAEFSYMEPGELKSWPIPPPVPAAK-IEKDRTVMPCGTVVTTVTAVKTKPRVDVGRAS 280
           + TA F   + GE +  P PPP+P A+ + K++   P G       +++   R   G  S
Sbjct: 415 TATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFG-WS 473

Query: 281 PLSSDSPVKTPIKVKVIEKDISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQ 340
           P   DSP    ++      +    ++  R   +   L    T+LL L   D   E+ +  
Sbjct: 474 PEPCDSPGTPTLESSPAGPEKPHDSLDSR---IEMLLKEQRTKLLFLREPDSDTELQMEG 530

Query: 341 LSESSKLKLKSP 352
              SS     SP
Sbjct: 531 SPISSSSSQLSP 542


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 43/175 (24%), Positives = 72/175 (41%), Gaps = 23/175 (13%)

Query: 270 TKPRVDVGRA---SPLSSDSP-------VKTPIKVKVIEKDIS--VQAIACRSAPVSKTL 317
           T+P  D   A   SPLS ++        V++P+  +   ++ S  +Q +A   AP  +T 
Sbjct: 480 TEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETP 539

Query: 318 SSSDTELLVLNGSDPV-AEVAIRQLS----ESSKLKLKSPRKKSTIIISGISKTSLSQDH 372
           + + + L     ++   AEV          E + L+L+ P  + T      +   L    
Sbjct: 540 AEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAAT 599

Query: 373 DAALMQGYTASVDSTHQEDAPSH-----PERAAASAPPEEAESAQASLAPKPQED 422
           +A+  +   A V     E+AP+       E A A   P  AE A A + P P E+
Sbjct: 600 EASAEEA-PAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE 653



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 54/269 (20%), Positives = 103/269 (38%), Gaps = 37/269 (13%)

Query: 232 PGELKSWPIPPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTP 291
           P  ++   IPP +P+ +++ DR+     T   T+  +    +VD  + +  S    V   
Sbjct: 109 PESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIV--- 165

Query: 292 IKVKVIEKDISVQAIACRSAPVSKTLSSSDTELL-VLNGSDPVAEVAIRQLSESSKLKLK 350
           +  +        +  A +     K  +S   E     N ++ + +  I + S + + K  
Sbjct: 166 VISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKG 225

Query: 351 SP-------RKKSTIII----SGISKTSLSQDHDAA-----------LMQGYTAS----- 383
            P       R++ T+ +    S + K + ++    +           L++  TA      
Sbjct: 226 PPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRP 285

Query: 384 VDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQEDELDSWDLEKEPQAAAWSSQV- 442
            + TH +  PS  E   A A    AE++     P  +E  L  +  E +P +A  S  V 
Sbjct: 286 AEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVE 345

Query: 443 ----LLDPDGDEL-SESSMSVLEPGTAKK 466
               +L P  +E  SE   + + P  A+K
Sbjct: 346 LLAEILPPSAEESPSEEPPAEILPPPAEK 374


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 33.1 bits (74), Expect = 0.66
 Identities = 81/384 (21%), Positives = 115/384 (29%), Gaps = 62/384 (16%)

Query: 176  ISEAGRSSEGLLATATVP-----LDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYM 230
            IS     +  L  + T P        F   P  P + TL+  S   S V    T   S+ 
Sbjct: 864  ISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPAT-TLSPASTTSSGVSEESTT--SHS 920

Query: 231  EPGELKSWPIPPPVPAAKIEKDRTVM---PCGTVVTTVTAVKTKPRVDVGRASPLSSDSP 287
             PG   +   P       + +  T     P  T  T + A  T   V     SP+SS S 
Sbjct: 921  RPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGST 980

Query: 288  VKTPIKVKVIEKDISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKL 347
              T +        +S ++    S+P      S DT L         A      +SE S  
Sbjct: 981  ETTALPGSTTTAGLSEKSTTFYSSP-----RSPDTTL-------SPASTTSSGVSEESTT 1028

Query: 348  KLKSPRKKSTIIISGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEE 407
                P    T    G                  + ++    QE   SH    +       
Sbjct: 1029 SHSRPGSTHTTAFPG------------------STTMPGVSQESTASHSSPGSTDTTLSP 1070

Query: 408  AESAQASLAPKPQEDELDSWDLEKEPQAAAWSSQVLLDPDGDELS---ESS----MSVLE 460
              +  +SL P       +S      P     S++  L PD    S   E+S     S   
Sbjct: 1071 RSTTASSLGP-------ESTTFHSGP----GSTETTLLPDNTTASGLLEASTPVHSSTGS 1119

Query: 461  PGTAKKHKGGILRKGAKLFFRRRHQQKDPGMSQSHNDLVFLE---QPEGSRRKGITLTRI 517
            P T     G   R+G    F+     KD   +       F+E      GS     T    
Sbjct: 1120 PRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFS 1179

Query: 518  LNKKLLSRHRNKNTMNGAPVEPCT 541
             +     R     T++ +PV P T
Sbjct: 1180 ASSTTFGRSEESTTVHSSPVAPAT 1203


>gi|20270323 zinc finger protein 653 [Homo sapiens]
          Length = 615

 Score = 33.1 bits (74), Expect = 0.66
 Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 15/105 (14%)

Query: 361 SGISKTSLSQDHDAALMQGYTASVDSTHQEDAPSHPERAAASAPPEEAESAQASLAPKPQ 420
           SG+  + L ++   A+M+G  A   +  +   PS  +  A +    + E     L  K +
Sbjct: 343 SGVPGSGLGEEVPCAMMEGVAAYTQTEPEGSQPSTMDATAVAGIETKKEKEDLCLLKKEE 402

Query: 421 EDELDSWDL------EKEPQAAAWSSQVLLDPDGDELSESSMSVL 459
           ++E  + +L        EP+A A         DG+EL  S MS +
Sbjct: 403 KEEPVAPELATTVPESAEPEAEA---------DGEELDGSDMSAI 438


>gi|191252814 RIMS binding protein 3B [Homo sapiens]
          Length = 1639

 Score = 32.7 bits (73), Expect = 0.87
 Identities = 37/142 (26%), Positives = 54/142 (38%), Gaps = 6/142 (4%)

Query: 107 ELKLLVRNIHVLLLSEPGASGHINAVCVVQLNDPVQRFSST---LTKNTPDLMWEEEFTF 163
           E +L ++ I       P  SG  +   V  L +P+ + SS      K    L   +  + 
Sbjct: 195 ERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSA 254

Query: 164 ELNAKSKELHLQISEAGRSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSV 223
           E+  +S+ L L  S    S +GLL+T    LD F    S     T +   A  S    S 
Sbjct: 255 EVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSS 314

Query: 224 TAEFSYMEPGELKSWPIPPPVP 245
                   PG  +  P P P+P
Sbjct: 315 P---DTSTPGSRRLSPPPSPLP 333


>gi|191252806 RIMS binding protein 3C [Homo sapiens]
          Length = 1639

 Score = 32.7 bits (73), Expect = 0.87
 Identities = 37/142 (26%), Positives = 54/142 (38%), Gaps = 6/142 (4%)

Query: 107 ELKLLVRNIHVLLLSEPGASGHINAVCVVQLNDPVQRFSST---LTKNTPDLMWEEEFTF 163
           E +L ++ I       P  SG  +   V  L +P+ + SS      K    L   +  + 
Sbjct: 195 ERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSA 254

Query: 164 ELNAKSKELHLQISEAGRSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSV 223
           E+  +S+ L L  S    S +GLL+T    LD F    S     T +   A  S    S 
Sbjct: 255 EVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSS 314

Query: 224 TAEFSYMEPGELKSWPIPPPVP 245
                   PG  +  P P P+P
Sbjct: 315 P---DTSTPGSRRLSPPPSPLP 333


>gi|149944516 tet oncogene family member 3 [Homo sapiens]
          Length = 1660

 Score = 32.7 bits (73), Expect = 0.87
 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 6/60 (10%)

Query: 237 SWPIPPPVPAAKIEKDRTVMPCGTVVTTV----TAVKTKPRVDVGRASPLSSDSPVKTPI 292
           SWP+P P P    E ++ +      + +V     A+ TKP+V V   +P SS +P  +P+
Sbjct: 314 SWPMPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKV--EAPSSSPAPAPSPV 371


>gi|148806881 hypothetical protein LOC57608 [Homo sapiens]
          Length = 1359

 Score = 32.7 bits (73), Expect = 0.87
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 389 QEDAPSHPERAAASAPPEEAESAQASLAPKPQED---ELDSWDLEKEPQAAAW--SSQVL 443
           +E++ S    +++S+   EAE  Q + A   QED     +S ++  EPQ   W   S V 
Sbjct: 845 EEESSSSSSSSSSSSEESEAEPQQENRAHCRQEDVGFRGNSPEMRVEPQPRMWVPESPVC 904

Query: 444 LDPDGDELSESSMSVLEPG 462
               G+  SES    L+PG
Sbjct: 905 RSGRGESKSESWSEELQPG 923


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.126    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,134,405
Number of Sequences: 37866
Number of extensions: 1047209
Number of successful extensions: 4242
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 118
Number of HSP's that attempted gapping in prelim test: 4075
Number of HSP's gapped (non-prelim): 271
length of query: 541
length of database: 18,247,518
effective HSP length: 107
effective length of query: 434
effective length of database: 14,195,856
effective search space: 6161001504
effective search space used: 6161001504
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.