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Search of human proteins with 38372923
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38372923 basigin isoform 4 [Homo sapiens]
(205 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38372923 basigin isoform 4 [Homo sapiens] 417 e-117
gi|38372919 basigin isoform 1 precursor [Homo sapiens] 397 e-111
gi|38372925 basigin isoform 2 precursor [Homo sapiens] 397 e-111
gi|9257240 neuroplastin isoform a precursor [Homo sapiens] 161 3e-40
gi|6912646 neuroplastin isoform b precursor [Homo sapiens] 161 3e-40
gi|238624149 neuroplastin isoform d precursor [Homo sapiens] 155 3e-38
gi|238624147 neuroplastin isoform c precursor [Homo sapiens] 155 3e-38
gi|38348215 embigin [Homo sapiens] 62 4e-10
gi|118572606 hemicentin 1 [Homo sapiens] 46 2e-05
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 45 4e-05
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 44 1e-04
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 44 1e-04
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 43 2e-04
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 43 2e-04
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 43 2e-04
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 43 2e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 42 3e-04
gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] 42 3e-04
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 42 3e-04
gi|236464356 neuregulin 1 isoform HRG-gamma3 [Homo sapiens] 42 5e-04
gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens] 42 5e-04
gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens] 42 5e-04
gi|236462984 neuregulin 1 isoform HRG-gamma2 [Homo sapiens] 42 5e-04
gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens] 42 5e-04
gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens] 42 5e-04
gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens] 42 5e-04
gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens] 42 5e-04
gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens] 42 5e-04
gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens] 42 5e-04
gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens] 42 5e-04
>gi|38372923 basigin isoform 4 [Homo sapiens]
Length = 205
Score = 417 bits (1072), Expect = e-117
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MKQSDASPQERVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAML 60
MKQSDASPQERVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAML
Sbjct: 1 MKQSDASPQERVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAML 60
Query: 61 VCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYR 120
VCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYR
Sbjct: 61 VCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYR 120
Query: 121 CNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDA 180
CNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDA
Sbjct: 121 CNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDA 180
Query: 181 GSAPLKSSGQHQNDKGKNVRQRNSS 205
GSAPLKSSGQHQNDKGKNVRQRNSS
Sbjct: 181 GSAPLKSSGQHQNDKGKNVRQRNSS 205
>gi|38372919 basigin isoform 1 precursor [Homo sapiens]
Length = 385
Score = 397 bits (1020), Expect = e-111
Identities = 197/207 (95%), Positives = 200/207 (96%), Gaps = 4/207 (1%)
Query: 3 QSDASPQER----VDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA 58
+ DA P ++ VDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA
Sbjct: 179 KEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA 238
Query: 59 MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ 118
MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ
Sbjct: 239 MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ 298
Query: 119 YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD 178
YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD
Sbjct: 299 YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD 358
Query: 179 DAGSAPLKSSGQHQNDKGKNVRQRNSS 205
DAGSAPLKSSGQHQNDKGKNVRQRNSS
Sbjct: 359 DAGSAPLKSSGQHQNDKGKNVRQRNSS 385
>gi|38372925 basigin isoform 2 precursor [Homo sapiens]
Length = 269
Score = 397 bits (1020), Expect = e-111
Identities = 197/207 (95%), Positives = 200/207 (96%), Gaps = 4/207 (1%)
Query: 3 QSDASPQER----VDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA 58
+ DA P ++ VDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA
Sbjct: 63 KEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETA 122
Query: 59 MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ 118
MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ
Sbjct: 123 MLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQ 182
Query: 119 YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD 178
YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD
Sbjct: 183 YRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDD 242
Query: 179 DAGSAPLKSSGQHQNDKGKNVRQRNSS 205
DAGSAPLKSSGQHQNDKGKNVRQRNSS
Sbjct: 243 DAGSAPLKSSGQHQNDKGKNVRQRNSS 269
>gi|9257240 neuroplastin isoform a precursor [Homo sapiens]
Length = 282
Score = 161 bits (408), Expect = 3e-40
Identities = 84/189 (44%), Positives = 122/189 (64%), Gaps = 6/189 (3%)
Query: 19 GEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWY 76
GEY CV F+ P A I++ P + K SE+ NEG+ A + CKS P DW W
Sbjct: 98 GEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWR 156
Query: 77 KITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 136
K + ++N S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + L
Sbjct: 157 KKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 215
Query: 137 RVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKG 196
RVRSHLA LWPFLGI+AE+++LV II +YEKR++P++V DDD+ + P+K++ + N K
Sbjct: 216 RVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEP-AGPMKTNSTN-NHKD 273
Query: 197 KNVRQRNSS 205
KN+RQRN++
Sbjct: 274 KNLRQRNTN 282
>gi|6912646 neuroplastin isoform b precursor [Homo sapiens]
Length = 398
Score = 161 bits (408), Expect = 3e-40
Identities = 84/189 (44%), Positives = 122/189 (64%), Gaps = 6/189 (3%)
Query: 19 GEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWY 76
GEY CV F+ P A I++ P + K SE+ NEG+ A + CKS P DW W
Sbjct: 214 GEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWR 272
Query: 77 KITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 136
K + ++N S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + L
Sbjct: 273 KKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 331
Query: 137 RVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKG 196
RVRSHLA LWPFLGI+AE+++LV II +YEKR++P++V DDD+ + P+K++ + N K
Sbjct: 332 RVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEP-AGPMKTNSTN-NHKD 389
Query: 197 KNVRQRNSS 205
KN+RQRN++
Sbjct: 390 KNLRQRNTN 398
>gi|238624149 neuroplastin isoform d precursor [Homo sapiens]
Length = 278
Score = 155 bits (391), Expect = 3e-38
Identities = 82/189 (43%), Positives = 119/189 (62%), Gaps = 10/189 (5%)
Query: 19 GEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWY 76
GEY CV F+ P A I++ P + K SE+ NEG+ A + CKS P DW W
Sbjct: 98 GEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWR 156
Query: 77 KITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 136
K + ++N S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + L
Sbjct: 157 KKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 215
Query: 137 RVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKG 196
RVRSHLA LWPFLGI+AE+++LV II +YEKR++P++V D + P+K++ + N K
Sbjct: 216 RVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD-----AGPMKTNSTN-NHKD 269
Query: 197 KNVRQRNSS 205
KN+RQRN++
Sbjct: 270 KNLRQRNTN 278
>gi|238624147 neuroplastin isoform c precursor [Homo sapiens]
Length = 394
Score = 155 bits (391), Expect = 3e-38
Identities = 82/189 (43%), Positives = 119/189 (62%), Gaps = 10/189 (5%)
Query: 19 GEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWY 76
GEY CV F+ P A I++ P + K SE+ NEG+ A + CKS P DW W
Sbjct: 214 GEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWR 272
Query: 77 KITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 136
K + ++N S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + L
Sbjct: 273 KKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 331
Query: 137 RVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKG 196
RVRSHLA LWPFLGI+AE+++LV II +YEKR++P++V D + P+K++ + N K
Sbjct: 332 RVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD-----AGPMKTNSTN-NHKD 385
Query: 197 KNVRQRNSS 205
KN+RQRN++
Sbjct: 386 KNLRQRNTN 394
>gi|38348215 embigin [Homo sapiens]
Length = 327
Score = 61.6 bits (148), Expect = 4e-10
Identities = 52/159 (32%), Positives = 76/159 (47%), Gaps = 19/159 (11%)
Query: 17 QWGEYSCVFLPEP--MGTANI---QLHGP--PRVKAVKSSEHINEGETAMLVCKSESVPP 69
Q G YSC F E GT N +LHG P + V G++ +L CK ++ P
Sbjct: 136 QMGSYSCFFREEKEQRGTFNFKVPELHGKNKPLISYV--------GDSTVLTCKCQNCFP 187
Query: 70 VTDWAWYKITDSEDKALMNGSESRFFVSSSQGR-SELHIENLNMEADPGQYRCNGTSSKG 128
+ +W WY S K + +++ ++ + ++L I L +E D Y C G
Sbjct: 188 L-NWTWYSSNGSV-KVPVGVQMNKYVINGTYANETKLKITQL-LEEDGESYWCRALFQLG 244
Query: 129 SDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEK 167
+ I L V S+L L PFL IVAEV++LV I + EK
Sbjct: 245 ESEEHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEK 283
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 46.2 bits (108), Expect = 2e-05
Identities = 30/124 (24%), Positives = 59/124 (47%), Gaps = 15/124 (12%)
Query: 19 GEYSCV---FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWA 74
G Y+C+ + + +H PPR+++ + +NE A+L C ++ +P P +W
Sbjct: 4144 GHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINW- 4202
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 134
+D L+ ++ +++ EL +EN+ +E D G Y C ++ G D +
Sbjct: 4203 ------KKDNVLLANLLGKY---TAEPYGELILENVVLE-DSGFYTCVANNAAGEDTHTV 4252
Query: 135 TLRV 138
+L V
Sbjct: 4253 SLTV 4256
Score = 42.0 bits (97), Expect = 4e-04
Identities = 29/99 (29%), Positives = 53/99 (53%), Gaps = 10/99 (10%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PP +K S I ++ +L C +E VP +IT +D A++ G+ +R+ + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTP------RITWRKDGAVLAGNHARYSILEN 3765
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
LHI++ ++ D G+Y C T++ G+D+ I L+V
Sbjct: 3766 ---GFLHIQSAHV-TDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 41.6 bits (96), Expect = 5e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 13/116 (11%)
Query: 19 GEYSCVFLP---EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 75
G Y+CV + E +++++ PP + + + + + L+C+S+++PP T W
Sbjct: 2079 GRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPT-LTW 2137
Query: 76 YKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQ 131
K D G +S S+ RS L IE+ ++ D G+Y C T+ G +
Sbjct: 2138 LK--DGHPLLKKPG------LSISENRSVLKIEDAQVQ-DTGRYTCEATNVAGKTE 2184
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 25/131 (19%)
Query: 19 GEYSCVFLP---EPMGTANIQLHGPPRVKAVKSSE----HINEGETAMLVCKSESVPPVT 71
GEY+C+ + E ++ ++ PP +K S ++ EG + L C+S +VPP
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 72 DWAWYK----ITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSK 127
WYK IT+S ++ + LHI+ + +D GQY C +
Sbjct: 3091 -ITWYKNGRMITESTHVEILADGQM------------LHIKKAEV-SDTGQYVCRAINVA 3136
Query: 128 GSDQAIITLRV 138
G D L V
Sbjct: 3137 GRDDKNFHLNV 3147
Score = 39.7 bits (91), Expect = 0.002
Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 17/119 (14%)
Query: 19 GEYSCVF---LPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWA 74
G Y+CV E T ++ +H P + +N+GE L CK+ +P P W
Sbjct: 4235 GFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWT 4294
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAI 133
+ N + S G SEL IE ++ E D G Y C +S G +AI
Sbjct: 4295 F------------NNNIIPAHFDSVNGHSELVIERVSKE-DSGTYVCTAENSVGFVKAI 4340
Score = 38.1 bits (87), Expect = 0.005
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 19 GEYSCVFLP---EPMGTANIQLHGPPRVKAVKS--SEHINEGETAMLVCKSESVPPVTDW 73
G Y+CV E + +H PP ++ +E + L CK+ PV
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG-NPVPVI 1952
Query: 74 AWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAI 133
WYK D L++GS S F++ Q + IE+ + +D G Y+C +S G+ +
Sbjct: 1953 TWYK-----DNRLLSGSTSMTFLNRGQ---IIDIESAQI-SDAGIYKCVAINSAGATELF 2003
Query: 134 ITLRV 138
+L+V
Sbjct: 2004 YSLQV 2008
Score = 37.7 bits (86), Expect = 0.007
Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 17/127 (13%)
Query: 19 GEYSCVFLPEPMGTAN----IQLHGPPRVKA--VKSSEHINEGETAMLVCKSESVP-PVT 71
G Y+C+ G A + + PP V + S + GE LVC + +P P+
Sbjct: 3220 GNYTCI-ASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLI 3278
Query: 72 DWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQ 131
W + K + +G R VS++ S L+I + +D G+Y C T+ G +
Sbjct: 3279 QWL------KDGKPIASGETERIRVSANG--STLNIYGA-LTSDTGKYTCVATNPAGEED 3329
Query: 132 AIITLRV 138
I L V
Sbjct: 3330 RIFNLNV 3336
Score = 33.9 bits (76), Expect = 0.099
Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 12/106 (11%)
Query: 35 IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDSEDKALMNGSESR 93
+ +H PP+++ + G+ + C ++ P PV W+ L++G
Sbjct: 1165 LNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWS-----KGGSTMLVDGEHH- 1218
Query: 94 FFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 139
VS+ G L I+ +D G Y C T+ G+D+ ITL V+
Sbjct: 1219 --VSNPDGT--LSIDQAT-PSDAGIYTCVATNIAGTDETEITLHVQ 1259
Score = 32.3 bits (72), Expect = 0.29
Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 19 GEYSCVFLPEPMGTAN---IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 75
GEY C+ E +A + + PP+V + ++ G ++C + P
Sbjct: 587 GEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP----- 641
Query: 76 YKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIIT 135
KI + + + GS R+ ++S L I+N + D G Y C ++S G+D+ T
Sbjct: 642 -KIAWTVNDMFIVGSH-RYRMTSD---GTLFIKNAAPK-DAGIYGCLASNSAGTDKQNST 695
Query: 136 LR 137
LR
Sbjct: 696 LR 697
Score = 31.2 bits (69), Expect = 0.64
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 19 GEYSCVFLPEPMGTA---NIQLHGPPRVKAV-KSSEHIN--EGETAMLVCKSESVPPVTD 72
G Y CV + T ++ +H PP + +S E+I+ E + L C++ +P +
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP-LPS 2417
Query: 73 WAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQA 132
W+K D +L N V G L + ME D GQY C ++ G ++
Sbjct: 2418 ITWFK--DGWPVSLSNS------VRILSGGRMLRLMQTTME-DAGQYTCVVRNAAGEERK 2468
Query: 133 IITLRV 138
I L V
Sbjct: 2469 IFGLSV 2474
Score = 30.8 bits (68), Expect = 0.84
Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 10/105 (9%)
Query: 35 IQLHGPPRVKAVKSSEHIN-EGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESR 93
+ +H PP +K+ SE + + + L C + +P + IT +D +N ++
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPS------ITWLKDDQPVNTAQGN 1873
Query: 94 FFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
+ SS GR L I +E D G+Y C T++ G Q I L V
Sbjct: 1874 LKIQSS-GRV-LQIAKTLLE-DAGRYTCVATNAAGETQQHIQLHV 1915
Score = 30.0 bits (66), Expect = 1.4
Identities = 31/126 (24%), Positives = 47/126 (37%), Gaps = 18/126 (14%)
Query: 19 GEYSCVFLPEPMGTA---NIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWA 74
G Y CV + T ++Q+H P + + + L C++ +P P W
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW- 2045
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNME--ADPGQYRCNGTSSKGSDQA 132
L +GS F + Q S I L +D G+Y C ++ G Q
Sbjct: 2046 -----------LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQR 2094
Query: 133 IITLRV 138
I LRV
Sbjct: 2095 DIDLRV 2100
Score = 29.6 bits (65), Expect = 1.9
Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 14/125 (11%)
Query: 19 GEYSCVFLPEPMGTANIQ----LHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWA 74
G Y C+ + GT Q + PP V V ++ + GE A+L C S +
Sbjct: 495 GFYECIAVSSA-GTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDY-NLT 552
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 134
W + + D L + R + S L ++++ D G+Y C +S GS A +
Sbjct: 553 WQR--NDRDVRLAEPARIRTLANLS-----LELKSVKFN-DAGEYHCMVSSEGGSSAASV 604
Query: 135 TLRVR 139
L V+
Sbjct: 605 FLTVQ 609
Score = 28.5 bits (62), Expect = 4.2
Identities = 43/152 (28%), Positives = 61/152 (40%), Gaps = 18/152 (11%)
Query: 9 QERVDSDDQWGEYSCVFLPEP---MGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSE 65
QE D D G+Y+CV + E G + + PP + + G L C +
Sbjct: 760 QETQDLDA--GDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQ 817
Query: 66 SVPPVTDWAWYKITDSEDKALMNGSESRFFVSS-SQGRS-ELHIENLNMEADPGQYRCNG 123
P T W ++ + M F VSS SQ R+ L I NL +D G Y C
Sbjct: 818 GYPEPTI-KWRRLDN------MPIFSRPFSVSSISQLRTGALFILNL-WASDKGTYICEA 869
Query: 124 TSSKGSDQAIITLRVRSHLAALWPFLGIVAEV 155
+ G Q+ T+ V +A P +GI V
Sbjct: 870 ENQFGKIQSETTVTVTGLVA---PLIGISPSV 898
Score = 27.7 bits (60), Expect = 7.1
Identities = 32/126 (25%), Positives = 49/126 (38%), Gaps = 17/126 (13%)
Query: 19 GEYSCVFLPEPMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDW 73
G Y+CV G+A+ + +H PP ++ S H+ +L C++ P P W
Sbjct: 3963 GRYTCV-ARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITW 4021
Query: 74 AWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAI 133
++ +N S V S G L I E D G Y C + G+
Sbjct: 4022 -------QKEGINVNTSGRNHAVLPSGG---LQISRAVRE-DAGTYMCVAQNPAGTALGK 4070
Query: 134 ITLRVR 139
I L V+
Sbjct: 4071 IKLNVQ 4076
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 45.1 bits (105), Expect = 4e-05
Identities = 41/133 (30%), Positives = 54/133 (40%), Gaps = 20/133 (15%)
Query: 11 RVDSDDQWGEYSC-VFLPEPMGTANIQLH--GPPRVKAVKSSEHINEGETAMLVCKSESV 67
RV D G+Y C P A I LH PP V + GET L C +
Sbjct: 3267 RVAQQDS-GQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGT 3325
Query: 68 PPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSE-LHIENLNMEADPGQYRCNGTSS 126
PP+T + W ++ S + R+E LH E E D G+YRC T+
Sbjct: 3326 PPLT-FQWSRVGSS-------------LPGRATARNELLHFERAAPE-DSGRYRCRVTNK 3370
Query: 127 KGSDQAIITLRVR 139
GS +A L V+
Sbjct: 3371 VGSAEAFAQLLVQ 3383
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 35/137 (25%)
Query: 19 GEYSCVFLPEPMGTANIQLH----------GPPRVKAVKSSEHINEGETAMLVCKSESVP 68
G Y C+ +GTA Q+ G P+V+A ++ + G TA L C + P
Sbjct: 3181 GTYVCL-AQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSP 3239
Query: 69 -PVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNM----EADPGQYRCNG 123
P W+ + S + L + L + + D GQY CN
Sbjct: 3240 APTIHWSKLR-------------------SPLPWQHRLEGDTLIIPRVAQQDSGQYICNA 3280
Query: 124 TSSKGSDQAIITLRVRS 140
TS G +A I L V S
Sbjct: 3281 TSPAGHAEATIILHVES 3297
Score = 32.3 bits (72), Expect = 0.29
Identities = 38/132 (28%), Positives = 50/132 (37%), Gaps = 30/132 (22%)
Query: 19 GEYSCVFLPEPMGTANIQLH---------GPPRVKAVKSSEHINEGETAMLVC--KSESV 67
G Y CV P GTA ++ PP VK SS + EG+T L C +
Sbjct: 2021 GFYLCV-ATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAH 2079
Query: 68 PPVTDWAWYKITDS-EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSS 126
VT WY+ S ++GS R S AD G+Y C +
Sbjct: 2080 AQVT---WYRRGGSLPPHTQVHGSRLRLPQVS--------------PADSGEYVCRVENG 2122
Query: 127 KGSDQAIITLRV 138
G +A IT+ V
Sbjct: 2123 SGPKEASITVSV 2134
Score = 30.8 bits (68), Expect = 0.84
Identities = 31/102 (30%), Positives = 40/102 (39%), Gaps = 11/102 (10%)
Query: 39 GPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSS 98
G PRV+ ++ G T L C++ VP T W K GS S
Sbjct: 1954 GGPRVQVSPERTQVHAGRTVRLYCRAAGVPSAT-ITWRK---------EGGSLPPQARSE 2003
Query: 99 SQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 140
+ L I + AD G Y C TS G+ QA I + V S
Sbjct: 2004 RTDIATLLIPAIT-TADAGFYLCVATSPAGTAQARIQVVVLS 2044
Score = 30.0 bits (66), Expect = 1.4
Identities = 12/27 (44%), Positives = 19/27 (70%)
Query: 114 ADPGQYRCNGTSSKGSDQAIITLRVRS 140
AD GQYRC T++ G+ Q+ + L V++
Sbjct: 3548 ADAGQYRCTATNAAGTTQSHVLLLVQA 3574
Score = 29.3 bits (64), Expect = 2.4
Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 27/130 (20%)
Query: 20 EYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVC--KSESVPPVTDWAWYK 77
E S + EP G+ L P V+ SS + EG+T L C ++ VT W+K
Sbjct: 2417 EASVLVTIEPAGSVPA-LGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVT---WHK 2472
Query: 78 ITDSEDKALMNGSESRFFVSSSQGRSELHIENLNM----EADPGQYRCNGTSSKGSDQAI 133
S R ++H L + AD G+Y C S G+ +A
Sbjct: 2473 RG-----------------GSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEAS 2515
Query: 134 ITLRVRSHLA 143
+ + ++ L+
Sbjct: 2516 VLVTIQQRLS 2525
Score = 28.9 bits (63), Expect = 3.2
Identities = 22/92 (23%), Positives = 37/92 (40%), Gaps = 12/92 (13%)
Query: 49 SEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIE 108
S+ + G +C ++S P W + L NG + + L I
Sbjct: 1780 SQSVRPGADVTFICTAKSKSPAYTLVWTR--------LHNG---KLPTRAMDFNGILTIR 1828
Query: 109 NLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 140
N+ + +D G Y C G++ DQ TL V++
Sbjct: 1829 NVQL-SDAGTYVCTGSNMFAMDQGTATLHVQA 1859
Score = 28.5 bits (62), Expect = 4.2
Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 18/86 (20%)
Query: 48 SSEHINEGETAMLVC--KSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSEL 105
SS H+ EG+T L C ++ VT WYK S +R SQ R L
Sbjct: 2932 SSSHVTEGQTLDLNCVVPGQAHAQVT---WYKRGGS--------LPARHQTHGSQLR--L 2978
Query: 106 HIENLNMEADPGQYRCNGTSSKGSDQ 131
H+ + AD G+Y C S G +Q
Sbjct: 2979 HLVS---PADSGEYVCRAASGPGPEQ 3001
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/126 (29%), Positives = 63/126 (50%), Gaps = 14/126 (11%)
Query: 16 DQWGEYSCVFLPE----PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVT 71
DQ GEY C L + + I ++ PP + K++ ++ G+ +L C++ +VP +
Sbjct: 188 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTG-VSVGQKGILSCEASAVP-MA 245
Query: 72 DWAWYKITDSEDKALMNGSESRFFVSSSQGR-SELHIENLNMEADPGQYRCNGTSSKGSD 130
++ W+K E+ L G + ++GR S L N++ E D G Y C T+ G+
Sbjct: 246 EFQWFK----EETRLATGLDGMRI--ENKGRMSTLTFFNVS-EKDYGNYTCVATNKLGNT 298
Query: 131 QAIITL 136
A ITL
Sbjct: 299 NASITL 304
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 20/117 (17%)
Query: 10 ERVDSDDQWGEYSC-VFLPEPMGTANIQL--HGPPRVKAVKSSEHINEGETAMLVCKSES 66
+ VD D+ G Y+C V T+ + L PP++ + S +NEG + L+C +
Sbjct: 96 QNVDVYDE-GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG 154
Query: 67 VP-PVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCN 122
P P W + E + FVS + L I ++ + G+Y C+
Sbjct: 155 RPEPTVTWRHLSV-----------KEGQGFVSEDE---YLEISDIKRD-QSGEYECS 196
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/126 (29%), Positives = 63/126 (50%), Gaps = 14/126 (11%)
Query: 16 DQWGEYSCVFLPE----PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVT 71
DQ GEY C L + + I ++ PP + K++ ++ G+ +L C++ +VP +
Sbjct: 195 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTG-VSVGQKGILSCEASAVP-MA 252
Query: 72 DWAWYKITDSEDKALMNGSESRFFVSSSQGR-SELHIENLNMEADPGQYRCNGTSSKGSD 130
++ W+K E+ L G + ++GR S L N++ E D G Y C T+ G+
Sbjct: 253 EFQWFK----EETRLATGLDGMRI--ENKGRMSTLTFFNVS-EKDYGNYTCVATNKLGNT 305
Query: 131 QAIITL 136
A ITL
Sbjct: 306 NASITL 311
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 20/117 (17%)
Query: 10 ERVDSDDQWGEYSC-VFLPEPMGTANIQL--HGPPRVKAVKSSEHINEGETAMLVCKSES 66
+ VD D+ G Y+C V T+ + L PP++ + S +NEG + L+C +
Sbjct: 103 QNVDVYDE-GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG 161
Query: 67 VP-PVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCN 122
P P W + E + FVS + L I ++ + G+Y C+
Sbjct: 162 RPEPTVTWRHLSV-----------KEGQGFVSEDE---YLEISDIKRD-QSGEYECS 203
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 43.1 bits (100), Expect = 2e-04
Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 15/124 (12%)
Query: 19 GEYSCVFLPEPMGTA---NIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWA 74
G+YSC T+ +++H P +++ + +++ +TA+L C+++ VP P+ W
Sbjct: 2457 GDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW- 2515
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 134
+D+ ++ RF + L I+ + + D G Y C ++S GSD+
Sbjct: 2516 ------RKDRVPLDPRSPRFEILP---EGSLRIQPV-LAQDAGHYLCLASNSAGSDRQGR 2565
Query: 135 TLRV 138
LRV
Sbjct: 2566 DLRV 2569
Score = 38.1 bits (87), Expect = 0.005
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 19/135 (14%)
Query: 14 SDDQWGEYSCVF---LPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPV 70
S + G Y C+ MG + + PP ++ EG A L CK+ P
Sbjct: 2817 SPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEP 2876
Query: 71 TDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 130
IT +D ++G+E +F + S EL ++NL + D G Y C ++
Sbjct: 2877 ------NITWDKDGQPVSGAEGKFTIQPS---GELLVKNLEGQ-DAGTYTCT------AE 2920
Query: 131 QAIITLRVRSHLAAL 145
A+ R R HL L
Sbjct: 2921 NAVGRARRRVHLTIL 2935
Score = 36.6 bits (83), Expect = 0.015
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 13/123 (10%)
Query: 19 GEYSCVFLP---EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 75
G YSCV + E +Q+H PP + + + + E+ L C+S ++PP +W
Sbjct: 855 GRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPV-LSW 913
Query: 76 YKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIIT 135
+K + + L E R V S ++ L ++ ++ D G Y C + G +
Sbjct: 914 WK----DGRPL----EPRPGVHLSADKALLQVDRADV-WDAGHYTCEALNQAGRSEKHYN 964
Query: 136 LRV 138
L V
Sbjct: 965 LNV 967
Score = 35.8 bits (81), Expect = 0.026
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 41 PRVKA--VKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSS 98
PR+++ V H+ EG+ L C+++ PP D AW K D G RF++
Sbjct: 2025 PRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PDVAWLK--DGSPLGQDMGPHLRFYLDG 2081
Query: 99 SQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
L ++ L +D G Y C + G D + T+ V
Sbjct: 2082 ----GSLVLKGLR-ASDAGAYTCVAHNPAGEDARLHTVNV 2116
Score = 34.7 bits (78), Expect = 0.058
Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 14/132 (10%)
Query: 10 ERVDSDDQWGEYSCV---FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSES 66
E+VD D+ G Y+C E +++ PP ++ ++ + E + L C +
Sbjct: 662 EKVDLRDE-GIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASG 720
Query: 67 VPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSS 126
VPP D +W+K S V+ S L IE + +D G YRC ++
Sbjct: 721 VPP-PDVSWFKGHQPVS--------SWMGVTVSVDGRVLRIEQAQL-SDAGSYRCVASNV 770
Query: 127 KGSDQAIITLRV 138
GS + LRV
Sbjct: 771 AGSTELRYGLRV 782
Score = 28.5 bits (62), Expect = 4.2
Identities = 29/117 (24%), Positives = 48/117 (41%), Gaps = 23/117 (19%)
Query: 28 EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP------PVTDWAWYKITDS 81
E + T +Q+ PPR+ + + ++ S S+P P + WYK
Sbjct: 1735 EKLFTLRVQV--PPRIAGLDLEQ------VTAILNSSVSLPCDVHAHPNPEVTWYK---- 1782
Query: 82 EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
+ +AL G E V G L + + +D G Y C ++ G DQ ++ L V
Sbjct: 1783 DSQALSLGEE----VFLLPGTHTLQLGRARL-SDSGMYTCEALNAAGRDQKLVQLSV 1834
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 43.1 bits (100), Expect = 2e-04
Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 15/124 (12%)
Query: 19 GEYSCVFLPEPMGTA---NIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWA 74
G+YSC T+ +++H P +++ + +++ +TA+L C+++ VP P+ W
Sbjct: 3648 GDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW- 3706
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 134
+D+ ++ RF + L I+ + + D G Y C ++S GSD+
Sbjct: 3707 ------RKDRVPLDPRSPRFEILP---EGSLRIQPV-LAQDAGHYLCLASNSAGSDRQGR 3756
Query: 135 TLRV 138
LRV
Sbjct: 3757 DLRV 3760
Score = 40.8 bits (94), Expect = 8e-04
Identities = 35/123 (28%), Positives = 44/123 (35%), Gaps = 16/123 (13%)
Query: 19 GEYSCVFLPE---PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 75
G YSC E T + PP V AV + + GE A+LVC++ VPP W
Sbjct: 673 GNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPP-PRVIW 731
Query: 76 YKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIIT 135
Y+ G +L I E D G Y C + G A I
Sbjct: 732 YR-----------GGLEMILAPEGSSSGKLRIP-AAQERDAGTYTCRAVNELGDASAEIQ 779
Query: 136 LRV 138
L V
Sbjct: 780 LAV 782
Score = 38.1 bits (87), Expect = 0.005
Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 13/97 (13%)
Query: 41 PRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
P+V SS+H ++G + C + P P W+ E +AL +SR V +
Sbjct: 608 PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWS------RESQALQE--DSRIHVDA- 658
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 136
+ L I+ + E D G Y C T+ G+DQ +TL
Sbjct: 659 --QGTLIIQGVAPE-DAGNYSCQATNEVGTDQETVTL 692
Score = 38.1 bits (87), Expect = 0.005
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 19/135 (14%)
Query: 14 SDDQWGEYSCVF---LPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPV 70
S + G Y C+ MG + + PP ++ EG A L CK+ P
Sbjct: 4008 SPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEP 4067
Query: 71 TDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 130
IT +D ++G+E +F + S EL ++NL + D G Y C ++
Sbjct: 4068 ------NITWDKDGQPVSGAEGKFTIQPS---GELLVKNLEGQ-DAGTYTCT------AE 4111
Query: 131 QAIITLRVRSHLAAL 145
A+ R R HL L
Sbjct: 4112 NAVGRARRRVHLTIL 4126
Score = 36.6 bits (83), Expect = 0.015
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 13/123 (10%)
Query: 19 GEYSCVFLP---EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 75
G YSCV + E +Q+H PP + + + + E+ L C+S ++PP +W
Sbjct: 2046 GRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPV-LSW 2104
Query: 76 YKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIIT 135
+K + + L E R V S ++ L ++ ++ D G Y C + G +
Sbjct: 2105 WK----DGRPL----EPRPGVHLSADKALLQVDRADV-WDAGHYTCEALNQAGHSEKHYN 2155
Query: 136 LRV 138
L V
Sbjct: 2156 LNV 2158
Score = 35.8 bits (81), Expect = 0.026
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 41 PRVKA--VKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSS 98
PR+++ V H+ EG+ L C+++ PP D AW K D G RF++
Sbjct: 3216 PRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PDVAWLK--DGSPLGQDMGPHLRFYLDG 3272
Query: 99 SQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
L ++ L +D G Y C + G D + T+ V
Sbjct: 3273 ----GSLVLKGLR-ASDAGAYTCVAHNPAGEDARLHTVNV 3307
Score = 34.7 bits (78), Expect = 0.058
Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 14/132 (10%)
Query: 10 ERVDSDDQWGEYSCV---FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSES 66
E+VD D+ G Y+C E +++ PP ++ ++ + E + L C +
Sbjct: 1853 EKVDLRDE-GIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASG 1911
Query: 67 VPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSS 126
VPP D +W+K S V+ S L IE + +D G YRC ++
Sbjct: 1912 VPP-PDVSWFKGHQPVS--------SWMGVTVSVDGRVLRIEQAQL-SDAGSYRCVASNV 1961
Query: 127 KGSDQAIITLRV 138
GS + LRV
Sbjct: 1962 AGSTELRYGLRV 1973
Score = 33.1 bits (74), Expect = 0.17
Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 38 HGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVS 97
H PP++ + + + EG+ L C + P+ + W K + + L GS
Sbjct: 882 HAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLK----DGRPLPPGSR-----H 932
Query: 98 SSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 139
S + LH++ ++ G+Y C T++ GS + L V+
Sbjct: 933 SIRADGSLHLDRA-LQEHAGRYSCVATNTAGSQHRDVELVVQ 973
Score = 33.1 bits (74), Expect = 0.17
Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 23/125 (18%)
Query: 19 GEYSCVFLPEPMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDW 73
G Y C P G+A+ + + PP+V+ + GE L C +E P P W
Sbjct: 1095 GHYECT-ASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSW 1153
Query: 74 AWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAI 133
S+D ++ G + V + R+ +D G+YRC ++S G D
Sbjct: 1154 -------SKDGVVLQGRGPQGSVHFAAIRT----------SDAGRYRCEASNSAGVDAWE 1196
Query: 134 ITLRV 138
+ LRV
Sbjct: 1197 VELRV 1201
Score = 31.2 bits (69), Expect = 0.64
Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 15/125 (12%)
Query: 19 GEYSCVFLPEPMGT----ANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWA 74
G Y C + GT A I + PP + ++ GETA+L C+ V A
Sbjct: 492 GTYECTAVSRA-GTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCR------VLGEA 544
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 134
Y +T D ++ S R + L I + + D G+Y+C +++ G +A +
Sbjct: 545 PYNLTWVRDWRVLPASTGRV---AQLADLSLEISGI-IPTDGGRYQCVASNANGVTRASV 600
Query: 135 TLRVR 139
L VR
Sbjct: 601 WLLVR 605
Score = 30.0 bits (66), Expect = 1.4
Identities = 37/128 (28%), Positives = 48/128 (37%), Gaps = 23/128 (17%)
Query: 19 GEYSCVFLPEPMGTANIQ-------LHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PV 70
G YSCV TA Q + PPR+ + NEG A L C + VP P
Sbjct: 951 GRYSCV----ATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPT 1006
Query: 71 TDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 130
W E AL S + S +G L I + + D G Y C T++ G
Sbjct: 1007 ITWT------KETNALT--SRGPHYNVSKEG--TLLIAQPSAQ-DAGAYVCTATNTVGFS 1055
Query: 131 QAIITLRV 138
+ L V
Sbjct: 1056 SQEMRLSV 1063
Score = 28.5 bits (62), Expect = 4.2
Identities = 29/117 (24%), Positives = 48/117 (41%), Gaps = 23/117 (19%)
Query: 28 EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP------PVTDWAWYKITDS 81
E + T +Q+ PPR+ + + ++ S S+P P + WYK
Sbjct: 2926 EKLFTLRVQV--PPRIAGLDLEQ------VTAILNSSVSLPCDVHAHPNPEVTWYK---- 2973
Query: 82 EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
+ +AL G E V G L + + +D G Y C ++ G DQ ++ L V
Sbjct: 2974 DSQALSLGEE----VFLLPGTHTLQLGRARL-SDSGMYTCEALNAAGRDQKLVQLSV 3025
Score = 27.3 bits (59), Expect = 9.3
Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 9/127 (7%)
Query: 19 GEYSCVFLPEPMGTANIQLH----GPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWA 74
G Y+C + E +G A+ ++ P++ + + G +A+L C++ PP T
Sbjct: 761 GTYTCRAVNE-LGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPT--V 817
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 134
++ D + L G+ R S L E++ E D Y C + G QA
Sbjct: 818 TWRRGDGQPLGLRLGA-GRGSRSRQPDSGVLFFESVAPE-DQAPYVCEARNVFGKVQAEA 875
Query: 135 TLRVRSH 141
L V H
Sbjct: 876 RLIVTGH 882
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 43.1 bits (100), Expect = 2e-04
Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 15/124 (12%)
Query: 19 GEYSCVFLPEPMGTA---NIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWA 74
G+YSC T+ +++H P +++ + +++ +TA+L C+++ VP P+ W
Sbjct: 2366 GDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW- 2424
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 134
+D+ ++ RF + L I+ + + D G Y C ++S GSD+
Sbjct: 2425 ------RKDRVPLDPRSPRFEILP---EGSLRIQPV-LAQDAGHYLCLASNSAGSDRQGR 2474
Query: 135 TLRV 138
LRV
Sbjct: 2475 DLRV 2478
Score = 38.1 bits (87), Expect = 0.005
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 19/135 (14%)
Query: 14 SDDQWGEYSCVF---LPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPV 70
S + G Y C+ MG + + PP ++ EG A L CK+ P
Sbjct: 2726 SPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEP 2785
Query: 71 TDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 130
IT +D ++G+E +F + S EL ++NL + D G Y C ++
Sbjct: 2786 ------NITWDKDGQPVSGAEGKFTIQPS---GELLVKNLEGQ-DAGTYTCT------AE 2829
Query: 131 QAIITLRVRSHLAAL 145
A+ R R HL L
Sbjct: 2830 NAVGRARRRVHLTIL 2844
Score = 36.6 bits (83), Expect = 0.015
Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 13/123 (10%)
Query: 19 GEYSCVFLP---EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 75
G YSCV + E +Q+H PP + + + + E+ L C+S ++PP +W
Sbjct: 764 GRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPV-LSW 822
Query: 76 YKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIIT 135
+K + + L E R V S ++ L ++ ++ D G Y C + G +
Sbjct: 823 WK----DGRPL----EPRPGVHLSADKALLQVDRADV-WDAGHYTCEALNQAGHSEKHYN 873
Query: 136 LRV 138
L V
Sbjct: 874 LNV 876
Score = 35.8 bits (81), Expect = 0.026
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 41 PRVKA--VKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSS 98
PR+++ V H+ EG+ L C+++ PP D AW K D G RF++
Sbjct: 1934 PRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PDVAWLK--DGSPLGQDMGPHLRFYLDG 1990
Query: 99 SQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
L ++ L +D G Y C + G D + T+ V
Sbjct: 1991 ----GSLVLKGLR-ASDAGAYTCVAHNPAGEDARLHTVNV 2025
Score = 34.7 bits (78), Expect = 0.058
Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 14/132 (10%)
Query: 10 ERVDSDDQWGEYSCV---FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSES 66
E+VD D+ G Y+C E +++ PP ++ ++ + E + L C +
Sbjct: 571 EKVDLRDE-GIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASG 629
Query: 67 VPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSS 126
VPP D +W+K S V+ S L IE + +D G YRC ++
Sbjct: 630 VPP-PDVSWFKGHQPVS--------SWMGVTVSVDGRVLRIEQAQL-SDAGSYRCVASNV 679
Query: 127 KGSDQAIITLRV 138
GS + LRV
Sbjct: 680 AGSTELRYGLRV 691
Score = 28.5 bits (62), Expect = 4.2
Identities = 29/117 (24%), Positives = 48/117 (41%), Gaps = 23/117 (19%)
Query: 28 EPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP------PVTDWAWYKITDS 81
E + T +Q+ PPR+ + + ++ S S+P P + WYK
Sbjct: 1644 EKLFTLRVQV--PPRIAGLDLEQ------VTAILNSSVSLPCDVHAHPNPEVTWYK---- 1691
Query: 82 EDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
+ +AL G E V G L + + +D G Y C ++ G DQ ++ L V
Sbjct: 1692 DSQALSLGEE----VFLLPGTHTLQLGRARL-SDSGMYTCEALNAAGRDQKLVQLSV 1743
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 42.7 bits (99), Expect = 2e-04
Identities = 49/181 (27%), Positives = 79/181 (43%), Gaps = 34/181 (18%)
Query: 16 DQWGEYSCVFLPEPMG---TANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVP-PVT 71
+ G YSC+ G A++ + P + + GETA+L C + P P
Sbjct: 668 EDMGIYSCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRL 727
Query: 72 DWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQ 131
+W ++D + +E FF +++Q L I + +E D G+Y C +++ G+++
Sbjct: 728 NW-------TKDDGPLLVTERHFFAAANQ---LLIIVDAGLE-DAGKYTCIMSNTLGTER 776
Query: 132 AIITLRVRS------------HLAALWPFLGIVAEVLV-------LVTIIFIYEKRRKPE 172
I L V S H W +GIV V+V L+ +I IY RRK E
Sbjct: 777 GHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNE 836
Query: 173 D 173
D
Sbjct: 837 D 837
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 42.4 bits (98), Expect = 3e-04
Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 15/100 (15%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PP V+ +K++E L C+ PP + WYK DK + S+ ++ ++S
Sbjct: 5523 PPIVETLKNAE-------VSLECELSGTPPF-EVVWYK-----DKRQLRSSK-KYKIASK 5568
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 139
+ +HI N++ +D G+Y C + GSD + T++++
Sbjct: 5569 NFHTSIHILNVDT-SDIGEYHCKAQNEVGSDTCVCTVKLK 5607
Score = 39.3 bits (90), Expect = 0.002
Identities = 28/125 (22%), Positives = 59/125 (47%), Gaps = 11/125 (8%)
Query: 19 GEYSCVF---LPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAW 75
G+Y+C + ++++ PP + +G L C+ + PP +W
Sbjct: 7374 GDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPF-HVSW 7432
Query: 76 YKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIIT 135
YK + + L +G ++ + S + +HI N++ AD G+Y+C T+ GSD + +
Sbjct: 7433 YK----DKRELRSGK--KYKIMSENFLTSIHILNVDA-ADIGEYQCKATNDVGSDTCVGS 7485
Query: 136 LRVRS 140
+ +++
Sbjct: 7486 IALKA 7490
Score = 38.9 bits (89), Expect = 0.003
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 19 GEYSCV---FLPEPMGTANIQLHGPPR-VKAVKSSEHINEGETAMLVCKSESVPPVTDWA 74
G+Y+C + +A + + PPR +K ++ S + + E CK P +
Sbjct: 7280 GQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKV-L 7338
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 134
WYK ++ + S+ R S E+H NL++E D G Y C ++ GS +
Sbjct: 7339 WYK----DETEIQESSKFRMSFVDSVAVLEMH--NLSVE-DSGDYTCEAHNAAGSASSST 7391
Query: 135 TLRVR 139
+L+V+
Sbjct: 7392 SLKVK 7396
Score = 37.7 bits (86), Expect = 0.007
Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 9/100 (9%)
Query: 32 TANIQLHGPPR-VKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGS 90
+A + + PP VK V S + GE+A L CK + PV W+K +K L +
Sbjct: 3728 SATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKG-SPVIQVTWFK----NNKELSESN 3782
Query: 91 ESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 130
R + +S+ + L I ++ +E D G Y C + GSD
Sbjct: 3783 TVRMYFVNSE--AILDITDVKVE-DSGSYSCEAVNDVGSD 3819
Score = 37.7 bits (86), Expect = 0.007
Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 12/116 (10%)
Query: 19 GEYSCVFLPEPMG---TANIQLHGPPR-VKAVKSSEHINEGETAMLVCKSESVPPVTDWA 74
G Y+C G +AN+ + P V+ ++ S+ + +G+ L CK PP+
Sbjct: 4274 GTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPI-KIT 4332
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 130
W+ + D+ + S+ R +S + + L + ++ +E D G+Y C + GSD
Sbjct: 4333 WF----ANDREIKESSKHR--MSFVESTAVLRLTDVGIE-DSGEYMCEAQNEAGSD 4381
Score = 37.7 bits (86), Expect = 0.007
Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 35 IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRF 94
+ + PP S +G +L C+ PP + W K D+ + S+ +F
Sbjct: 6452 LTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPF-EVVWVK-----DRKQVRNSK-KF 6504
Query: 95 FVSSSQGRSELHIENLNMEA-DPGQYRCNGTSSKGSDQAIITLRVR 139
++S + LHI LN+EA D G+Y C T+ GSD +++ +
Sbjct: 6505 KITSKHFDTSLHI--LNLEASDVGEYHCKATNEVGSDTCSCSVKFK 6548
Score = 36.6 bits (83), Expect = 0.015
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVP-PVTDWAWYKITDSEDKALMNGSESRFFVSS 98
PP+++A+ S I+EG+ + C P P W+ + + + + RF + +
Sbjct: 33328 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWS------CGGRKIHSQEQGRFHIEN 33381
Query: 99 SQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRS 140
+ + L I ++ + D G Y + + GSD A + + +RS
Sbjct: 33382 TDDLTTLIIMDVQKQ-DGGLYTLSLGNEFGSDSATVNIHIRS 33422
Score = 32.3 bits (72), Expect = 0.29
Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 8/107 (7%)
Query: 32 TANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSE 91
T + +L P + S++INEG+ + C+ S P + W+K L
Sbjct: 33125 TLSKELSDAPAFISQPRSQNINEGQNVLFTCEI-SGEPSPEIEWFK------NNLPISIS 33177
Query: 92 SRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
S +S S+ L I N ++ +D G+Y + +G A +L V
Sbjct: 33178 SNVSISRSRNVYSLEIRNASV-SDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 32.0 bits (71), Expect = 0.38
Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 12/126 (9%)
Query: 19 GEYSCVF---LPEPMGTANIQLHGPPR-VKAVKSSEHINEGETAMLVCKSESVPPVTDWA 74
G+Y+C + + M +A + + PP+ VK +++S+ +GE+ L CK P + +
Sbjct: 6339 GQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEI-KVS 6397
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAII 134
W++ DSE ++ +S + L I + E D G Y C + G
Sbjct: 6398 WFR-NDSE-----LHESWKYNMSFINSVALLTINEASAE-DSGDYICEAHNGVGDASCST 6450
Query: 135 TLRVRS 140
L V++
Sbjct: 6451 ALTVKA 6456
Score = 31.6 bits (70), Expect = 0.49
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 13/112 (11%)
Query: 32 TANIQLHG----PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALM 87
TA++Q+ P + +K + ++ G + ++ CK PP++ +W+ E +
Sbjct: 7670 TASLQVSDRTVPPSFTRKLKETNGLS-GSSVVMECKVYGSPPISV-SWFH----EGNEIS 7723
Query: 88 NGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVR 139
+G ++ + + L + N+ E+D G Y C T+ GSD+ L VR
Sbjct: 7724 SGR--KYQTTLTDNTCALTV-NMLEESDSGDYTCIATNMAGSDECSAPLTVR 7772
Score = 30.8 bits (68), Expect = 0.84
Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 15/90 (16%)
Query: 54 EGETAMLVCKSESVPPVTDWAWY----KITDSEDKALMNGSESRFFVSSSQGRSELHIEN 109
EG VCK E+ T WY ++ +SE ++ ++ G + L++++
Sbjct: 31581 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSE----------KYEITYEDGVAILYVKD 31630
Query: 110 LNMEADPGQYRCNGTSSKGSDQAIITLRVR 139
+ + D G YRC + G D + L V+
Sbjct: 31631 IT-KLDDGTYRCKVVNDYGEDSSYAELFVK 31659
Score = 30.0 bits (66), Expect = 1.4
Identities = 28/132 (21%), Positives = 51/132 (38%), Gaps = 18/132 (13%)
Query: 19 GEYSCVFLPEPMGTANIQLH-------GPPRVKAVKSSEHINEGETAMLVCKSESVPPV- 70
G+YSC P+G+A+ PP + GE+A C P+
Sbjct: 8125 GQYSCT-ATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIK 8183
Query: 71 TDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSD 130
WA + + + +G ++ +S + + L + ++ + D GQY C + G D
Sbjct: 8184 VSWA------KDSREIRSGG--KYQISYLENSAHLTVLKVD-KGDSGQYTCYAVNEVGKD 8234
Query: 131 QAIITLRVRSHL 142
L ++ L
Sbjct: 8235 SCTAQLNIKERL 8246
Score = 29.6 bits (65), Expect = 1.9
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 23/129 (17%)
Query: 19 GEYSCVFLPEP----MGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWA 74
GEY C E + I P K K E + E + ML+ + PP +
Sbjct: 4368 GEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDV-MLLAEVAGTPPF-EIT 4425
Query: 75 WYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNM----EADPGQYRCNGTSSKGSD 130
W+K ++ L +G + + F+ H+ +L + AD G+Y+C T+ GS
Sbjct: 4426 WFK----DNTILRSGRKYKTFIQD-------HLVSLQILKFVAADAGEYQCRVTNEVGSS 4474
Query: 131 --QAIITLR 137
A +TLR
Sbjct: 4475 ICSARVTLR 4483
Score = 29.6 bits (65), Expect = 1.9
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 8/74 (10%)
Query: 55 GETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEA 114
GE A L C+ P+ D WY+ K L+ +SR + SS GR+ +
Sbjct: 30547 GEAAQLSCQIVG-RPLPDIKWYRF----GKELI---QSRKYKMSSDGRTHTLTVMTEEQE 30598
Query: 115 DPGQYRCNGTSSKG 128
D G Y C T+ G
Sbjct: 30599 DEGVYTCIATNEVG 30612
Score = 28.9 bits (63), Expect = 3.2
Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 24/132 (18%)
Query: 19 GEYSCVFLPEPMGTANIQLHGPPR---------VKAVKSSEHINEGETAMLVCKSESVPP 69
G+YSC P+GTA+ R +K V S + GE+A C P
Sbjct: 6243 GQYSCS-ASNPLGTASSSARLTAREPKKSPFFDIKPV--SIDVIAGESADFECHVTGAQP 6299
Query: 70 VTDWAWYKITDSED-KALMNGSESRFFVSSSQGRSELHIENLNM-EADPGQYRCNGTSSK 127
+ +IT S+D K + G + + G + H+ L + + D GQY C T+
Sbjct: 6300 M------RITWSKDNKEIRPGGN---YTITCVGNTP-HLRILKVGKGDSGQYTCQATNDV 6349
Query: 128 GSDQAIITLRVR 139
G D L V+
Sbjct: 6350 GKDMCSAQLSVK 6361
>gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]
Length = 600
Score = 42.4 bits (98), Expect = 3e-04
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 15/152 (9%)
Query: 19 GEYSCVFLPEPMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWA 74
G+Y C + +G + ++GPP + + ++ +H GE + C S PP A
Sbjct: 394 GKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQT-QHALHGEKGQIKCFIRSTPPPDRIA 452
Query: 75 WYKITDSEDKALMNGSESRFFV---SSSQG-RSELHIENLNMEADPGQYRCNGTSSKGSD 130
W ++ L +G+ R+ V S+ +G S L I N+ Y C +S GSD
Sbjct: 453 W----SWKENVLESGTSGRYTVETISTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSD 508
Query: 131 QAIITLRVRSHLAALWPFLGIVAEVLVLVTII 162
II R++ + + G+ AE + + II
Sbjct: 509 TEII--RLKEQGSEMKSGAGLEAESVPMAVII 538
>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
Length = 778
Score = 42.4 bits (98), Expect = 3e-04
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 15/152 (9%)
Query: 19 GEYSCVFLPEPMGTAN----IQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWA 74
G+Y C + +G + ++GPP + + ++ +H GE + C S PP A
Sbjct: 394 GKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQT-QHALHGEKGQIKCFIRSTPPPDRIA 452
Query: 75 WYKITDSEDKALMNGSESRFFV---SSSQG-RSELHIENLNMEADPGQYRCNGTSSKGSD 130
W ++ L +G+ R+ V S+ +G S L I N+ Y C +S GSD
Sbjct: 453 W----SWKENVLESGTSGRYTVETISTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSD 508
Query: 131 QAIITLRVRSHLAALWPFLGIVAEVLVLVTII 162
II R++ + + G+ AE + + II
Sbjct: 509 TEII--RLKEQGSEMKSGAGLEAESVPMAVII 538
>gi|236464356 neuregulin 1 isoform HRG-gamma3 [Homo sapiens]
Length = 177
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
>gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens]
Length = 207
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
>gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens]
Length = 459
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
>gi|236462984 neuregulin 1 isoform HRG-gamma2 [Homo sapiens]
Length = 194
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
>gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens]
Length = 211
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
>gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens]
Length = 420
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
>gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens]
Length = 590
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 15 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 70
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 71 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 108
>gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens]
Length = 624
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 15 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 70
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 71 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 108
>gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens]
Length = 607
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 15 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 70
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 71 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 108
>gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens]
Length = 241
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
>gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens]
Length = 637
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 40 PPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSS 99
PPR+K +KS E G +L C++ S + W+K + ++ +
Sbjct: 36 PPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNR---KNKPQNIKIQKK 91
Query: 100 QGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRV 138
G+SEL I ++ AD G+Y C S G+D A + +
Sbjct: 92 PGKSELRINKASL-ADSGEYMCKVISKLGNDSASANITI 129
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,436,937
Number of Sequences: 37866
Number of extensions: 358688
Number of successful extensions: 1141
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 869
Number of HSP's gapped (non-prelim): 351
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.