Guide to the Human Genome
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Search of human proteins with 38201667

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38201667 inhibitor of growth family, member 1 isoform A
[Homo sapiens]
         (279 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38201667 inhibitor of growth family, member 1 isoform A [Homo...   574   e-164
gi|38201663 inhibitor of growth family, member 1 isoform C [Homo...   486   e-138
gi|38201661 inhibitor of growth family, member 1 isoform D [Homo...   486   e-138
gi|38201665 inhibitor of growth family, member 1 isoform B [Homo...   438   e-123
gi|4504695 inhibitor of growth family, member 2 [Homo sapiens]        330   1e-90
gi|189083821 inhibitor of growth family, member 4 isoform 9 [Hom...   191   6e-49
gi|189083826 inhibitor of growth family, member 4 isoform 3 [Hom...   190   1e-48
gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo...   190   1e-48
gi|189083828 inhibitor of growth family, member 4 isoform 4 [Hom...   189   2e-48
gi|18644730 inhibitor of growth family, member 5 [Homo sapiens]       180   1e-45
gi|189083830 inhibitor of growth family, member 4 isoform 5 [Hom...   152   3e-37
gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo...   119   3e-27
gi|189083832 inhibitor of growth family, member 4 isoform 6 [Hom...    87   1e-17
gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo...    52   8e-07
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    52   8e-07
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]       51   1e-06
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]       51   1e-06
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]                50   3e-06
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    47   2e-05
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    47   2e-05
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    47   2e-05
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor...    47   2e-05
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ...    47   2e-05
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ...    47   2e-05
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    46   4e-05
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    45   5e-05
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    45   7e-05
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    45   7e-05
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    45   7e-05
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...    44   2e-04

>gi|38201667 inhibitor of growth family, member 1 isoform A [Homo
           sapiens]
          Length = 279

 Score =  574 bits (1480), Expect = e-164
 Identities = 279/279 (100%), Positives = 279/279 (100%)

Query: 1   MLSPANGEQLHLVNYVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDECYERFSR 60
           MLSPANGEQLHLVNYVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDECYERFSR
Sbjct: 1   MLSPANGEQLHLVNYVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDECYERFSR 60

Query: 61  ETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELG 120
           ETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELG
Sbjct: 61  ETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELG 120

Query: 121 DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKK 180
           DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKK
Sbjct: 121 DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKK 180

Query: 181 AKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSC 240
           AKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSC
Sbjct: 181 AKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSC 240

Query: 241 VGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 279
           VGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
Sbjct: 241 VGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 279


>gi|38201663 inhibitor of growth family, member 1 isoform C [Homo
           sapiens]
          Length = 235

 Score =  486 bits (1251), Expect = e-138
 Identities = 234/234 (100%), Positives = 234/234 (100%)

Query: 46  EILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQ 105
           EILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQ
Sbjct: 2   EILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQ 61

Query: 106 VDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSN 165
           VDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSN
Sbjct: 62  VDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSN 121

Query: 166 HDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIG 225
           HDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIG
Sbjct: 122 HDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIG 181

Query: 226 CDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 279
           CDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
Sbjct: 182 CDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 235


>gi|38201661 inhibitor of growth family, member 1 isoform D [Homo
           sapiens]
          Length = 422

 Score =  486 bits (1251), Expect = e-138
 Identities = 233/236 (98%), Positives = 236/236 (100%)

Query: 44  YQEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRT 103
           +++ILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRT
Sbjct: 187 WKQILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRT 246

Query: 104 RQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENAS 163
           RQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENAS
Sbjct: 247 RQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENAS 306

Query: 164 SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEM 223
           SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEM
Sbjct: 307 SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEM 366

Query: 224 IGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 279
           IGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
Sbjct: 367 IGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR 422


>gi|38201665 inhibitor of growth family, member 1 isoform B [Homo
           sapiens]
          Length = 210

 Score =  438 bits (1126), Expect = e-123
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 70  MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA 129
           MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA
Sbjct: 1   MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA 60

Query: 130 GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR 189
           GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR
Sbjct: 61  GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR 120

Query: 190 SKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG 249
           SKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG
Sbjct: 121 SKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG 180

Query: 250 KWYCPKCRGENEKTMDKALEKSKKERAYNR 279
           KWYCPKCRGENEKTMDKALEKSKKERAYNR
Sbjct: 181 KWYCPKCRGENEKTMDKALEKSKKERAYNR 210


>gi|4504695 inhibitor of growth family, member 2 [Homo sapiens]
          Length = 280

 Score =  330 bits (845), Expect = 1e-90
 Identities = 160/270 (59%), Positives = 206/270 (76%), Gaps = 11/270 (4%)

Query: 7   GEQLHLVN-YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDECYERFSRETDGA 65
           GE+  L+  YV+DYL+ +ESLP D+QRNVS++RE+D KYQE LKE+D+ YE++ +E D  
Sbjct: 18  GERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKYKKEDDLN 77

Query: 66  QKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGN 125
           QK+R+   +QRALI SQELGDEKIQIV+QM+ELVENR RQ++ H + F+   E  + A +
Sbjct: 78  QKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAE-SERASD 136

Query: 126 SGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSK 185
             K  + +P+          +S+R RRQR +E+R+     +  +D     PKEKK+K++K
Sbjct: 137 KAKMDSSQPER---------SSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSKSAK 187

Query: 186 KKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNH 245
           KKKRSKAK EREASP +  IDPNEPTYCLCNQVSYGEMIGCDN++CPIEWFHFSCV L +
Sbjct: 188 KKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTY 247

Query: 246 KPKGKWYCPKCRGENEKTMDKALEKSKKER 275
           KPKGKWYCPKCRG+NEKTMDK+ EK+KK+R
Sbjct: 248 KPKGKWYCPKCRGDNEKTMDKSTEKTKKDR 277


>gi|189083821 inhibitor of growth family, member 4 isoform 9 [Homo
           sapiens]
          Length = 249

 Score =  191 bits (485), Expect = 6e-49
 Identities = 99/253 (39%), Positives = 148/253 (58%), Gaps = 15/253 (5%)

Query: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71
           Y+E YLDSIE+LPF+LQRN  LMR++D + +++  E+D+    Y   +R     +K  +L
Sbjct: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65

Query: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131
             +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +L +    S    +
Sbjct: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA--DLKEKQIESSDYDS 123

Query: 132 DRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSK 191
              KG+   +  K   K++ R R+         N D +   +   K K  +TS +     
Sbjct: 124 SSSKGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTAQKKLKLVRTSPEYGMPS 175

Query: 192 AK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG 249
               +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL  KP+G
Sbjct: 176 VTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRG 235

Query: 250 KWYCPKCRGENEK 262
           KW+CP+C  E +K
Sbjct: 236 KWFCPRCSQERKK 248


>gi|189083826 inhibitor of growth family, member 4 isoform 3 [Homo
           sapiens]
          Length = 246

 Score =  190 bits (483), Expect = 1e-48
 Identities = 98/255 (38%), Positives = 147/255 (57%), Gaps = 22/255 (8%)

Query: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71
           Y+E YLDSIE+LPF+LQRN  LMR++D + +++  E+D+    Y   +R     +K  +L
Sbjct: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65

Query: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131
             +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA                
Sbjct: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADL-------------- 111

Query: 132 DRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKK--AKTSKKKKR 189
            + K   ++  D  +SK  R Q+  +     S   + D+ A  T ++K    +TS +   
Sbjct: 112 -KEKQIESSDYDSSSSKEGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGM 170

Query: 190 SKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKP 247
                 +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL  KP
Sbjct: 171 PSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKP 230

Query: 248 KGKWYCPKCRGENEK 262
           +GKW+CP+C  E +K
Sbjct: 231 RGKWFCPRCSQERKK 245


>gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo
           sapiens]
          Length = 248

 Score =  190 bits (483), Expect = 1e-48
 Identities = 96/253 (37%), Positives = 148/253 (58%), Gaps = 16/253 (6%)

Query: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71
           Y+E YLDSIE+LPF+LQRN  LMR++D + +++  E+D+    Y   +R     +K  +L
Sbjct: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65

Query: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131
             +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +L +    S    +
Sbjct: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA--DLKEKQIESSDYDS 123

Query: 132 DRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSK 191
              KG+ +         R+++++      +   N D +   +   K K  +TS +     
Sbjct: 124 SSSKGKKS---------RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPS 174

Query: 192 AK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG 249
               +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL  KP+G
Sbjct: 175 VTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRG 234

Query: 250 KWYCPKCRGENEK 262
           KW+CP+C  E +K
Sbjct: 235 KWFCPRCSQERKK 247


>gi|189083828 inhibitor of growth family, member 4 isoform 4 [Homo
           sapiens]
          Length = 245

 Score =  189 bits (480), Expect = 2e-48
 Identities = 96/254 (37%), Positives = 147/254 (57%), Gaps = 21/254 (8%)

Query: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71
           Y+E YLDSIE+LPF+LQRN  LMR++D + +++  E+D+    Y   +R     +K  +L
Sbjct: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65

Query: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131
             +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA                
Sbjct: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADL-------------- 111

Query: 132 DRPKGEAAAQADKPNSK-RSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRS 190
            + K   ++  D  +SK R+++++      +   N D +   +   K K  +TS +    
Sbjct: 112 -KEKQIESSDYDSSSSKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMP 170

Query: 191 KAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPK 248
                +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL  KP+
Sbjct: 171 SVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPR 230

Query: 249 GKWYCPKCRGENEK 262
           GKW+CP+C  E +K
Sbjct: 231 GKWFCPRCSQERKK 244


>gi|18644730 inhibitor of growth family, member 5 [Homo sapiens]
          Length = 240

 Score =  180 bits (457), Expect = 1e-45
 Identities = 99/254 (38%), Positives = 141/254 (55%), Gaps = 27/254 (10%)

Query: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71
           Y+E YLDSIE+LP +LQRN  LMRE+D + ++   E+D     Y    +     Q+   L
Sbjct: 6   YLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQRVERL 65

Query: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQE---LGDTAGNSGK 128
             +Q A  + +E  D+K+Q+  Q  E+V+   R++D+ +  FEA  +    G    +SG 
Sbjct: 66  QKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDFESSGG 125

Query: 129 AGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKK 188
            G  + +G+             + +R +  R   +S  D       TPK+KK K   +  
Sbjct: 126 RGLKKGRGQ-------------KEKRGSRGRGRRTSEED-------TPKKKKHKGGSEFT 165

Query: 189 RSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPK 248
            +       +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +CPIEWFHF+CV L  KPK
Sbjct: 166 DTILSVH-PSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPK 224

Query: 249 GKWYCPKCRGENEK 262
           GKW+CP+C  E  K
Sbjct: 225 GKWFCPRCVQEKRK 238


>gi|189083830 inhibitor of growth family, member 4 isoform 5 [Homo
           sapiens]
          Length = 225

 Score =  152 bits (384), Expect = 3e-37
 Identities = 87/250 (34%), Positives = 130/250 (52%), Gaps = 33/250 (13%)

Query: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDECYERFSRETDGAQKRRMLHCV 74
           Y+E YLD++++             EID    E        Y   +R     +K  +L  +
Sbjct: 6   YLEHYLDNLKA-------------EIDKLATE--------YMSSARSLSSEEKLALLKQI 44

Query: 75  QRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRP 134
           Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +L +    S    +   
Sbjct: 45  QEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA--DLKEKQIESSDYDSSSS 102

Query: 135 KGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAK- 193
           KG+   +  K   K++ R R+         N D +   +   K K  +TS +        
Sbjct: 103 KGKKKGRTQK--EKKAARARSK------GKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTF 154

Query: 194 -AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWY 252
            +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL  KP+GKW+
Sbjct: 155 GSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWF 214

Query: 253 CPKCRGENEK 262
           CP+C  E +K
Sbjct: 215 CPRCSQERKK 224


>gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo
           sapiens]
          Length = 418

 Score =  119 bits (298), Expect = 3e-27
 Identities = 61/178 (34%), Positives = 87/178 (48%), Gaps = 10/178 (5%)

Query: 87  EKIQIVSQMVELVENRTRQVDSHVELFEAQQ-ELG-------DTAGNSGKAGADRPKGEA 138
           + +Q  +QM E    RT  + +  E F+    +LG       +T G S  +       + 
Sbjct: 231 QAVQATAQMKE--GRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQN 288

Query: 139 AAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREA 198
           A+ +   +    + + NN++    SS+       S             ++ +        
Sbjct: 289 ASSSAADSRSGRKSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQEISQQTTVVPESDSN 348

Query: 199 SPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKC 256
           S  D   DPNEP YC+CNQVSYGEM+GCDN +CPIEWFH+ CVGL   PKGKWYCP+C
Sbjct: 349 SQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQC 406



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 48/187 (25%), Positives = 90/187 (48%), Gaps = 11/187 (5%)

Query: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDECYERF---SRETDGAQKRRML 71
           Y+EDYL+ IE LP DL+   + MRE+D + Q  + +L++    F   +++     +   +
Sbjct: 3   YLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQM 62

Query: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131
             +++   ++ E  DEK+Q+ +Q+ +LV+   R++D  +  F+ + E  D AG +     
Sbjct: 63  ASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELE-ADNAGIT--EIL 119

Query: 132 DRPKGEAAAQADKPNSKRSRRQRNNENRE-NASSNHDHDDGASGTPKEKKAKTSKKKKRS 190
           +R   E    +   N+  +      E R+ N +S+H   D       EKK K+       
Sbjct: 120 ERRSLELDTPSQPVNNHHAHSHTPVEKRKYNPTSHHTTTDHI----PEKKFKSEALLSTL 175

Query: 191 KAKAERE 197
            + A +E
Sbjct: 176 TSDASKE 182


>gi|189083832 inhibitor of growth family, member 4 isoform 6 [Homo
           sapiens]
          Length = 179

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 47/149 (31%), Positives = 84/149 (56%), Gaps = 4/149 (2%)

Query: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71
           Y+E YLDSIE+LPF+LQRN  LMR++D + +++  E+D+    Y   +R     +K  +L
Sbjct: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65

Query: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131
             +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +      +   + +
Sbjct: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSS 125

Query: 132 DRPKGEAAAQADKPNSKRSRRQRNNENRE 160
            + K +   Q +K  + R+R +  N + E
Sbjct: 126 SKGKKKGRTQKEK-KAARARSKGKNSDEE 153


>gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo
          sapiens]
          Length = 92

 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 25/87 (28%), Positives = 50/87 (57%), Gaps = 3/87 (3%)

Query: 15 YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDECYERF---SRETDGAQKRRML 71
          Y+EDYL+ IE LP DL+   + MRE+D + Q  + +L++    F   +++     +   +
Sbjct: 3  YLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQM 62

Query: 72 HCVQRALIRSQELGDEKIQIVSQMVEL 98
            +++   ++ E  DEK+Q+ +Q+ +L
Sbjct: 63 ASIKKDYYKALEDADEKVQLANQIYDL 89


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 53/199 (26%), Positives = 80/199 (40%), Gaps = 43/199 (21%)

Query: 89  IQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAA-QADKPNS 147
           + +V  MV   E         V + +A+ + G      G     +PKG      A KP  
Sbjct: 234 VAVVESMVTATEVAPPPPPVEVPIRKAKTKEG-----KGPNARRKPKGSPRVPDAKKPKP 288

Query: 148 KR------------SRRQRNNENRENASSNHDHDDGA------------SGTPKEKKAKT 183
           K+            S+R+R++   ++     D DD +              +   KK +T
Sbjct: 289 KKVAPLKIKLGGFGSKRKRSSSEDDDLDVESDFDDASINSYSVSDGSTSRSSRSRKKLRT 348

Query: 184 SKKKKRSKAKAEREASPADLPIDPNEPTYC-LCNQVSYGEMIGCDNDECPIEWFHFSCVG 242
           +KKKK    K E E +  D   + +   YC +C Q   GE+I CD   CP   +H  C+ 
Sbjct: 349 TKKKK----KGEEEVTAVD-GYETDHQDYCEVCQQG--GEIILCDT--CP-RAYHMVCLD 398

Query: 243 --LNHKPKGKWYCPKCRGE 259
             +   P+GKW CP C  E
Sbjct: 399 PDMEKAPEGKWSCPHCEKE 417



 Score = 32.7 bits (73), Expect = 0.36
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 5/38 (13%)

Query: 221 GEMIGCDNDECPIEWFHFSCVG--LNHKPKGKWYCPKC 256
           GE++ CD   CP   +H  C+   L   P G+W CP+C
Sbjct: 459 GELLCCDT--CPSS-YHIHCLNPPLPEIPNGEWLCPRC 493



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 17/83 (20%)

Query: 145 PNSKRSRRQRNNENRENASSNHD---------------HDDGASGTPKEKKAKT--SKKK 187
           P SKR +++R    R+   S+ +                 +G+  TP +KK K    KK+
Sbjct: 66  PKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKE 125

Query: 188 KRSKAKAEREASPADLPIDPNEP 210
           K+SK+K + E    D   D  EP
Sbjct: 126 KKSKSKRKEEEEEEDDDDDSKEP 148


>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
          Length = 660

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 208 NEPTYCLCNQVSYG-EMIGCDNDECPIEWFHFSCVGLNHKPKG---KWYCPKCRGENEKT 263
           N P YC+C +      MIGCDN     EWFH  C+ +  K      +WYC +CR ++ K 
Sbjct: 24  NAPIYCICRKPDINCFMIGCDNCN---EWFHGDCIRITEKMAKAIREWYCRECREKDPKL 80

Query: 264 MDKALEKSKKERAYN 278
             +   K  +ER  N
Sbjct: 81  EIRYRHKKSRERDGN 95


>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
          Length = 656

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 7/75 (9%)

Query: 208 NEPTYCLCNQVSYG-EMIGCDNDECPIEWFHFSCVGLNHKPKG---KWYCPKCRGENEKT 263
           N P YC+C +      MIGCDN     EWFH  C+ +  K      +WYC +CR ++ K 
Sbjct: 24  NAPIYCICRKPDINCFMIGCDNCN---EWFHGDCIRITEKMAKAIREWYCRECREKDPKL 80

Query: 264 MDKALEKSKKERAYN 278
             +   K  +ER  N
Sbjct: 81  EIRYRHKKSRERDGN 95


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 14/85 (16%)

Query: 172  ASGTPKEKKAKTSK-KKKRSKAKAEREASPADLPIDPNEPTYCL-CNQVSYGEMIGCDND 229
            A  +  E+KAK +K K+KR K K E +    D         YC  C     GE++ CD  
Sbjct: 1291 ACASTNEEKAKNAKLKQKRRKIKTEPKQMHED---------YCFQCGDG--GELVMCDKK 1339

Query: 230  ECPIEWFHFSCVGLNHKPKGKWYCP 254
            +CP + +H  C+ L   P GKW CP
Sbjct: 1340 DCP-KAYHLLCLNLTQPPYGKWECP 1363



 Score = 35.8 bits (81), Expect = 0.043
 Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 15/124 (12%)

Query: 144 KPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADL 203
           KP  KRSR   + E    +S+  D  D  S    + +    K+     A A+ + S    
Sbjct: 628 KPLKKRSRASTDVEM--TSSAYRDTSDSDSRGLSDLQVGFGKQVDSPSATADADVSDVQ- 684

Query: 204 PIDPN----------EPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYC 253
            +D +          + T C   + S   +I C+ + C  + FH  C+GL   P  K+ C
Sbjct: 685 SMDSSLSRRGTGMSKKDTVCQICESSGDSLIPCEGECC--KHFHLECLGLASLPDSKFIC 742

Query: 254 PKCR 257
            +C+
Sbjct: 743 MECK 746


>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 11/78 (14%)

Query: 177  KEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWF 236
            +EK  KT KK +R +AK E +    D      E   C       G+++ CD   C  + +
Sbjct: 1215 EEKGKKTKKKTRRRRAKGEGKRQSED------ECFRC----GDGGQLVLCDRKFCT-KAY 1263

Query: 237  HFSCVGLNHKPKGKWYCP 254
            H SC+GL  +P GKW CP
Sbjct: 1264 HLSCLGLGKRPFGKWECP 1281



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 39/165 (23%), Positives = 69/165 (41%), Gaps = 19/165 (11%)

Query: 97  ELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRP-----KGEAAAQADKPNSKRSR 151
           + + ++T +  S+ +  EA   L   A     + A +P     +   AA +    SK S 
Sbjct: 560 DTITDKTARTSSY-KAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSS 618

Query: 152 RQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPT 211
              +    E + S  D     S +P E   +T  +   S  K+ER  +         E  
Sbjct: 619 PSASLTENEVSDSPGDEP---SESPYESADETQTEVSVSSKKSERGVTAK------KEYV 669

Query: 212 YCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKC 256
             LC +   G ++ C+   C    FH +C+GL+ +P+G++ C +C
Sbjct: 670 CQLCEKP--GSLLLCEGPCCGA--FHLACLGLSRRPEGRFTCSEC 710



 Score = 28.9 bits (63), Expect = 5.2
 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 221 GEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCR 257
           G ++ C++  CP   FH  C+ +   P G W+C  CR
Sbjct: 841 GSLLCCES--CPAA-FHPDCLNIE-MPDGSWFCNDCR 873


>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 11/78 (14%)

Query: 177  KEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWF 236
            +EK  KT KK +R +AK E +    D      E   C       G+++ CD   C  + +
Sbjct: 1215 EEKGKKTKKKTRRRRAKGEGKRQSED------ECFRC----GDGGQLVLCDRKFCT-KAY 1263

Query: 237  HFSCVGLNHKPKGKWYCP 254
            H SC+GL  +P GKW CP
Sbjct: 1264 HLSCLGLGKRPFGKWECP 1281



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 39/165 (23%), Positives = 69/165 (41%), Gaps = 19/165 (11%)

Query: 97  ELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRP-----KGEAAAQADKPNSKRSR 151
           + + ++T +  S+ +  EA   L   A     + A +P     +   AA +    SK S 
Sbjct: 560 DTITDKTARTSSY-KAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSS 618

Query: 152 RQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPT 211
              +    E + S  D     S +P E   +T  +   S  K+ER  +         E  
Sbjct: 619 PSASLTENEVSDSPGDEP---SESPYESADETQTEVSVSSKKSERGVTAK------KEYV 669

Query: 212 YCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKC 256
             LC +   G ++ C+   C    FH +C+GL+ +P+G++ C +C
Sbjct: 670 CQLCEKP--GSLLLCEGPCCGA--FHLACLGLSRRPEGRFTCSEC 710



 Score = 28.9 bits (63), Expect = 5.2
 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 221 GEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCR 257
           G ++ C++  CP   FH  C+ +   P G W+C  CR
Sbjct: 841 GSLLCCES--CPAA-FHPDCLNIE-MPDGSWFCNDCR 873


>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 11/78 (14%)

Query: 177  KEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWF 236
            +EK  KT KK +R +AK E +    D      E   C       G+++ CD   C  + +
Sbjct: 1215 EEKGKKTKKKTRRRRAKGEGKRQSED------ECFRC----GDGGQLVLCDRKFCT-KAY 1263

Query: 237  HFSCVGLNHKPKGKWYCP 254
            H SC+GL  +P GKW CP
Sbjct: 1264 HLSCLGLGKRPFGKWECP 1281



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 39/165 (23%), Positives = 69/165 (41%), Gaps = 19/165 (11%)

Query: 97  ELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRP-----KGEAAAQADKPNSKRSR 151
           + + ++T +  S+ +  EA   L   A     + A +P     +   AA +    SK S 
Sbjct: 560 DTITDKTARTSSY-KAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSS 618

Query: 152 RQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPT 211
              +    E + S  D     S +P E   +T  +   S  K+ER  +         E  
Sbjct: 619 PSASLTENEVSDSPGDEP---SESPYESADETQTEVSVSSKKSERGVTAK------KEYV 669

Query: 212 YCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKC 256
             LC +   G ++ C+   C    FH +C+GL+ +P+G++ C +C
Sbjct: 670 CQLCEKP--GSLLLCEGPCCGA--FHLACLGLSRRPEGRFTCSEC 710



 Score = 28.9 bits (63), Expect = 5.2
 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 221 GEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCR 257
           G ++ C++  CP   FH  C+ +   P G W+C  CR
Sbjct: 841 GSLLCCES--CPAA-FHPDCLNIE-MPDGSWFCNDCR 873


>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 11/78 (14%)

Query: 177  KEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWF 236
            +EK  KT KK +R +AK E +    D      E   C       G+++ CD   C  + +
Sbjct: 1215 EEKGKKTKKKTRRRRAKGEGKRQSED------ECFRC----GDGGQLVLCDRKFCT-KAY 1263

Query: 237  HFSCVGLNHKPKGKWYCP 254
            H SC+GL  +P GKW CP
Sbjct: 1264 HLSCLGLGKRPFGKWECP 1281



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 39/165 (23%), Positives = 69/165 (41%), Gaps = 19/165 (11%)

Query: 97  ELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRP-----KGEAAAQADKPNSKRSR 151
           + + ++T +  S+ +  EA   L   A     + A +P     +   AA +    SK S 
Sbjct: 560 DTITDKTARTSSY-KAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSS 618

Query: 152 RQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPT 211
              +    E + S  D     S +P E   +T  +   S  K+ER  +         E  
Sbjct: 619 PSASLTENEVSDSPGDEP---SESPYESADETQTEVSVSSKKSERGVTAK------KEYV 669

Query: 212 YCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKC 256
             LC +   G ++ C+   C    FH +C+GL+ +P+G++ C +C
Sbjct: 670 CQLCEKP--GSLLLCEGPCCGA--FHLACLGLSRRPEGRFTCSEC 710



 Score = 28.9 bits (63), Expect = 5.2
 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 221 GEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCR 257
           G ++ C++  CP   FH  C+ +   P G W+C  CR
Sbjct: 841 GSLLCCES--CPAA-FHPDCLNIE-MPDGSWFCNDCR 873


>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
           sapiens]
          Length = 1188

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 22/143 (15%)

Query: 143 DKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAK---TSKKKKRSKA------- 192
           D  +++R+ ++R   +  ++S+ H   D ++   K+KK      S  K++S+        
Sbjct: 29  DPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSELRHGPFYY 88

Query: 193 -KAEREASPADL-PIDPNEPTYC-LCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG 249
            K      P D+ P D     YC +C++   G+++ C+   CP   +H  C+ L  +P+G
Sbjct: 89  MKQPLTTDPVDVVPQDGRNDFYCWVCHRE--GQVLCCEL--CP-RVYHAKCLRLTSEPEG 143

Query: 250 KWYCPKCR----GENEKTMDKAL 268
            W+CP+C      E  +T  KA+
Sbjct: 144 DWFCPECEKITVAECIETQSKAM 166


>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
           sapiens]
          Length = 1160

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 22/143 (15%)

Query: 143 DKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAK---TSKKKKRSKA------- 192
           D  +++R+ ++R   +  ++S+ H   D ++   K+KK      S  K++S+        
Sbjct: 29  DPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSELRHGPFYY 88

Query: 193 -KAEREASPADL-PIDPNEPTYC-LCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG 249
            K      P D+ P D     YC +C++   G+++ C+   CP   +H  C+ L  +P+G
Sbjct: 89  MKQPLTTDPVDVVPQDGRNDFYCWVCHRE--GQVLCCEL--CP-RVYHAKCLRLTSEPEG 143

Query: 250 KWYCPKCR----GENEKTMDKAL 268
            W+CP+C      E  +T  KA+
Sbjct: 144 DWFCPECEKITVAECIETQSKAM 166


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 26/66 (39%), Positives = 38/66 (57%), Gaps = 10/66 (15%)

Query: 215 CNQVSYGE-MIGCDNDECPIEWFHFSCVGLNHKP--KGKWYCPKCRGENEKTMDKALEKS 271
           CN+   G  MIGCD+ +   +W+H+ CVG+   P  + +W+CPKC     K  DK   K 
Sbjct: 871 CNKPDDGSPMIGCDDCD---DWYHWPCVGIMTAPPEEMQWFCPKCA---NKKKDKK-HKK 923

Query: 272 KKERAY 277
           +K RA+
Sbjct: 924 RKHRAH 929



 Score = 28.9 bits (63), Expect = 5.2
 Identities = 14/41 (34%), Positives = 19/41 (46%)

Query: 157 ENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAERE 197
           E +E         D      K++K K  K+K+R K K ERE
Sbjct: 691 EEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKRERE 731


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 40/164 (24%), Positives = 71/164 (43%), Gaps = 14/164 (8%)

Query: 105 QVDSHVELFEAQQELGDTAG-----NSGKAGADRPKGEAAAQAD-KPNSKRSRRQRNNEN 158
           QV   V + +A+ + G   G        K G  + KG+  A    +     ++R++ + +
Sbjct: 232 QVPQPVPIRKAKTKEGKGPGVRKKIKGSKDGKKKGKGKKTAGLKFRFGGISNKRKKGSSS 291

Query: 159 RENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYC-LCNQ 217
            E+     D D  +  +   +   ++   K+SK + +++        + +   YC +C Q
Sbjct: 292 EEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDGYETDHQDYCEVCQQ 351

Query: 218 VSYGEMIGCDNDECPIEWFHFSCVG--LNHKPKGKWYCPKCRGE 259
              GE+I CD   CP   +H  C+   L   P+GKW CP C  E
Sbjct: 352 G--GEIILCDT--CP-RAYHLVCLDPELEKAPEGKWSCPHCEKE 390



 Score = 33.5 bits (75), Expect = 0.21
 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 134 PKGEAAAQADKPNSKRSRRQRNNENRENASSNHD-----HDDGASGTPKEKKAKTSKKKK 188
           PK +   +  +   K  R+++   N E + +  D       +G+  +P +KK K  K KK
Sbjct: 48  PKKKKPKKLKENKCKGKRKKKEGSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKK 107

Query: 189 RSKAKAEREASPAD 202
             KAK +++    D
Sbjct: 108 EKKAKRKKKDEDED 121



 Score = 32.3 bits (72), Expect = 0.47
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 5/38 (13%)

Query: 221 GEMIGCDNDECPIEWFHFSCVG--LNHKPKGKWYCPKC 256
           GE++ CD   CP   +H  C+   L   P G+W CP+C
Sbjct: 426 GELLCCD--ACPSS-YHLHCLNPPLPEIPNGEWLCPRC 460



 Score = 28.1 bits (61), Expect = 8.9
 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 6/66 (9%)

Query: 143 DKPNSKRSRRQRNN----ENRENAS--SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAER 196
           +K   KR +++ +N    EN E+    S  +  D +    K+KK K  K+KK  + K + 
Sbjct: 59  NKCKGKRKKKEGSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEKKAKRKKKDE 118

Query: 197 EASPAD 202
           +    D
Sbjct: 119 DEDDND 124


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
           [Homo sapiens]
          Length = 2000

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 43/153 (28%), Positives = 66/153 (43%), Gaps = 13/153 (8%)

Query: 127 GKAGADRPKGEAAA-QADK-PNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTS 184
           G  G  R KG +   Q+D+ P  +      ++ +  +AS      DG   T K K+ +  
Sbjct: 297 GLLGGKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGR---PDGPVRTKKLKRGRPG 353

Query: 185 KKKKRSKAKAEREASPADLPIDPNEPTYC-LCNQVSYGEMIGCDNDECPIEWFHFSCVG- 242
           +KKK+                + +   YC +C Q   GE+I CD   CP   +H  C+  
Sbjct: 354 RKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQG--GEIILCDT--CP-RAYHLVCLDP 408

Query: 243 -LNHKPKGKWYCPKCRGENEKTMDKALEKSKKE 274
            L+  P+GKW CP C  E  +   K  E+  +E
Sbjct: 409 ELDRAPEGKWSCPHCEKEGVQWEAKEEEEEYEE 441



 Score = 31.6 bits (70), Expect = 0.80
 Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 18/97 (18%)

Query: 163 SSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYC-LCNQVSYG 221
           S  H   +G     KE++ +  ++ +    K E +          +   YC +C     G
Sbjct: 419 SCPHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEED----------DHMEYCRVCKDG--G 466

Query: 222 EMIGCDNDECPIEWFHFSCVG--LNHKPKGKWYCPKC 256
           E++ CD     I  +H  C+   L   P G+W CP+C
Sbjct: 467 ELLCCD---ACISSYHIHCLNPPLPDIPNGEWLCPRC 500


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
           [Homo sapiens]
          Length = 1966

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 43/153 (28%), Positives = 66/153 (43%), Gaps = 13/153 (8%)

Query: 127 GKAGADRPKGEAAA-QADK-PNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTS 184
           G  G  R KG +   Q+D+ P  +      ++ +  +AS      DG   T K K+ +  
Sbjct: 297 GLLGGKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGR---PDGPVRTKKLKRGRPG 353

Query: 185 KKKKRSKAKAEREASPADLPIDPNEPTYC-LCNQVSYGEMIGCDNDECPIEWFHFSCVG- 242
           +KKK+                + +   YC +C Q   GE+I CD   CP   +H  C+  
Sbjct: 354 RKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQG--GEIILCDT--CP-RAYHLVCLDP 408

Query: 243 -LNHKPKGKWYCPKCRGENEKTMDKALEKSKKE 274
            L+  P+GKW CP C  E  +   K  E+  +E
Sbjct: 409 ELDRAPEGKWSCPHCEKEGVQWEAKEEEEEYEE 441



 Score = 31.6 bits (70), Expect = 0.80
 Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 18/97 (18%)

Query: 163 SSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYC-LCNQVSYG 221
           S  H   +G     KE++ +  ++ +    K E +          +   YC +C     G
Sbjct: 419 SCPHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEED----------DHMEYCRVCKDG--G 466

Query: 222 EMIGCDNDECPIEWFHFSCVG--LNHKPKGKWYCPKC 256
           E++ CD     I  +H  C+   L   P G+W CP+C
Sbjct: 467 ELLCCD---ACISSYHIHCLNPPLPDIPNGEWLCPRC 500


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
           [Homo sapiens]
          Length = 2059

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 43/153 (28%), Positives = 66/153 (43%), Gaps = 13/153 (8%)

Query: 127 GKAGADRPKGEAAA-QADK-PNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTS 184
           G  G  R KG +   Q+D+ P  +      ++ +  +AS      DG   T K K+ +  
Sbjct: 356 GLLGGKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGR---PDGPVRTKKLKRGRPG 412

Query: 185 KKKKRSKAKAEREASPADLPIDPNEPTYC-LCNQVSYGEMIGCDNDECPIEWFHFSCVG- 242
           +KKK+                + +   YC +C Q   GE+I CD   CP   +H  C+  
Sbjct: 413 RKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQG--GEIILCDT--CP-RAYHLVCLDP 467

Query: 243 -LNHKPKGKWYCPKCRGENEKTMDKALEKSKKE 274
            L+  P+GKW CP C  E  +   K  E+  +E
Sbjct: 468 ELDRAPEGKWSCPHCEKEGVQWEAKEEEEEYEE 500



 Score = 31.6 bits (70), Expect = 0.80
 Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 18/97 (18%)

Query: 163 SSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYC-LCNQVSYG 221
           S  H   +G     KE++ +  ++ +    K E +          +   YC +C     G
Sbjct: 478 SCPHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEED----------DHMEYCRVCKDG--G 525

Query: 222 EMIGCDNDECPIEWFHFSCVG--LNHKPKGKWYCPKC 256
           E++ CD     I  +H  C+   L   P G+W CP+C
Sbjct: 526 ELLCCD---ACISSYHIHCLNPPLPDIPNGEWLCPRC 559


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
            [Homo sapiens]
          Length = 2427

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 9/77 (11%)

Query: 178  EKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFH 237
            E+K+K  KKK++ K + + E +         E     C     G+++ C    CP + +H
Sbjct: 1824 EEKSKKFKKKQQGKRRTQGEITKE------REDECFSCGDA--GQLVSCKKPGCP-KVYH 1874

Query: 238  FSCVGLNHKPKGKWYCP 254
              C+ L  +P GKW CP
Sbjct: 1875 ADCLNLTKRPAGKWECP 1891



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 30/125 (24%), Positives = 48/125 (38%), Gaps = 13/125 (10%)

Query: 143  DKPNSKRSRRQRNNENRENASSNHDHDD---GASGTPKEKKAKTSKKKKRSKAKAEREAS 199
            DKP  ++ +R    + +     N D      G+ G     +  TS K+   +        
Sbjct: 1197 DKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGM 1256

Query: 200  PADLPIDPN-------EPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWY 252
            PA   +          +   C  N    GE++ C+   C    FH  C+GL   P+GK+ 
Sbjct: 1257 PASKKMQGERGGGAALKENVCQ-NCEKLGELLLCEAQCCGA--FHLECLGLTEMPRGKFI 1313

Query: 253  CPKCR 257
            C +CR
Sbjct: 1314 CNECR 1318



 Score = 31.6 bits (70), Expect = 0.80
 Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 4/37 (10%)

Query: 221  GEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCR 257
            G ++ CD+  CP   FH  C+ ++  P+G WYC  C+
Sbjct: 1448 GSLLCCDS--CPAA-FHRECLNIDI-PEGNWYCNDCK 1480


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,007,517
Number of Sequences: 37866
Number of extensions: 518242
Number of successful extensions: 4824
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 343
Number of HSP's that attempted gapping in prelim test: 3502
Number of HSP's gapped (non-prelim): 1318
length of query: 279
length of database: 18,247,518
effective HSP length: 101
effective length of query: 178
effective length of database: 14,423,052
effective search space: 2567303256
effective search space used: 2567303256
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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