Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 37622910
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]
(460 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens] 942 0.0
gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens] 486 e-137
gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens] 486 e-137
gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens] 400 e-111
gi|4502817 cholinergic receptor, muscarinic 2 [Homo sapiens] 391 e-109
gi|54792117 cholinergic receptor, muscarinic 2 [Homo sapiens] 391 e-109
gi|54792115 cholinergic receptor, muscarinic 2 [Homo sapiens] 391 e-109
gi|54792113 cholinergic receptor, muscarinic 2 [Homo sapiens] 391 e-109
gi|54792111 cholinergic receptor, muscarinic 2 [Homo sapiens] 391 e-109
gi|54792109 cholinergic receptor, muscarinic 2 [Homo sapiens] 391 e-109
gi|54792107 cholinergic receptor, muscarinic 2 [Homo sapiens] 391 e-109
gi|54792105 cholinergic receptor, muscarinic 2 [Homo sapiens] 391 e-109
gi|194018562 histamine receptor H3 [Homo sapiens] 218 9e-57
gi|149158709 histamine receptor H1 [Homo sapiens] 185 9e-47
gi|149158706 histamine receptor H1 [Homo sapiens] 185 9e-47
gi|149158704 histamine receptor H1 [Homo sapiens] 185 9e-47
gi|4504491 histamine receptor H1 [Homo sapiens] 185 9e-47
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 178 1e-44
gi|194353970 alpha-2A-adrenergic receptor [Homo sapiens] 169 5e-42
gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens] 161 1e-39
gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens] 157 2e-38
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 155 6e-38
gi|4503385 dopamine receptor D2 isoform long [Homo sapiens] 146 3e-35
gi|17986270 dopamine receptor D2 isoform short [Homo sapiens] 146 4e-35
gi|32483397 dopamine receptor D4 [Homo sapiens] 143 3e-34
gi|89191861 dopamine receptor D3 isoform a [Homo sapiens] 136 5e-32
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa... 132 9e-31
gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo sap... 130 3e-30
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 128 1e-29
gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo sap... 126 5e-29
>gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]
Length = 460
Score = 942 bits (2436), Expect = 0.0
Identities = 460/460 (100%), Positives = 460/460 (100%)
Query: 1 MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN 60
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
Sbjct: 1 MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN 60
Query: 61 NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS 120
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
Sbjct: 61 NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS 120
Query: 121 FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI 180
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
Sbjct: 121 FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI 180
Query: 181 QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS 240
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
Sbjct: 181 QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS 240
Query: 241 SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV 300
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
Sbjct: 241 SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV 300
Query: 301 VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE 360
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
Sbjct: 301 VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE 360
Query: 361 KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL 420
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
Sbjct: 361 KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL 420
Query: 421 CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC 460
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
Sbjct: 421 CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC 460
>gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]
Length = 590
Score = 486 bits (1252), Expect = e-137
Identities = 268/526 (50%), Positives = 325/526 (61%), Gaps = 97/526 (18%)
Query: 10 SPNITVLAP--GKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSL 67
SP+ T P G WQV FI TG+L+L T+ GN+LV++SFKVN +LKTVNNYFLLSL
Sbjct: 51 SPDGTTDDPLGGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSL 110
Query: 68 ACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSV 127
ACADLIIG SMNL+TTY++M WALG LACDLWLA+DYVASNASVMNLL+ISFDRYFS+
Sbjct: 111 ACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSI 170
Query: 128 TRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPI 187
TRPL+YRAKRT +RA +MIGLAW++SFVLWAPAILFWQY VG+RTV G+C+IQFLS+P
Sbjct: 171 TRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPT 230
Query: 188 ITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSET---------PGKGGGSS 238
ITFGTA+AAFY+PVT+M LYWRIY+ETE R +ELA LQ S T P S
Sbjct: 231 ITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSC 290
Query: 239 SSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDE---------------G 283
SS E Q + S GRC SWK E+ +
Sbjct: 291 SSYELQQQSMKRSNRRKYGRC------HFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAA 344
Query: 284 SMESLTSSEGEEPGSE------VVIKMP-------------------------MVDPEAQ 312
S+E+ SS+ E+ GSE +V+K+P MVD E +
Sbjct: 345 SLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERK 404
Query: 313 APTKQPPRS----------------------------------SPNTVKRPTKKGRDRAG 338
A Q +S +T P
Sbjct: 405 ADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLA 464
Query: 339 KGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPET 398
K + + Q+ KRK SLVKEKKAA+TLSAILLAFI+TWTPYNIMVLV+TFC C+P+T
Sbjct: 465 KRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKT 524
Query: 399 LWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRK 444
W LGYWLCY+NST+NP+CYALCNK FR TF++LLLC+ DK++ RK
Sbjct: 525 FWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKKKRRK 570
>gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens]
Length = 532
Score = 486 bits (1252), Expect = e-137
Identities = 257/491 (52%), Positives = 317/491 (64%), Gaps = 72/491 (14%)
Query: 23 WQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLY 82
W+V I T ++SL T+ GN+LV+ISFKVN++LKTVNNY+LLSLACADLIIG FSMNLY
Sbjct: 28 WEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLY 87
Query: 83 TTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRA 142
TTY+LMG WALG+LACDLWLALDYVASNASVMNLL+ISFDRYFS+TRPL+YRAKRTP+RA
Sbjct: 88 TTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRA 147
Query: 143 ALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVT 202
+MIGLAWL+SF+LWAPAIL WQYLVG+RTV +C IQFLS+P ITFGTA+AAFY+PV+
Sbjct: 148 GIMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLSEPTITFGTAIAAFYIPVS 207
Query: 203 VMCTLYWRIYRETENRARELAALQGSETPGKG---------------------------G 235
VM LY RIYRETE R ++LA LQGS++ K
Sbjct: 208 VMTILYCRIYRETEKRTKDLADLQGSDSVTKAEKRKPAHRALFRSCLRCPRPTLAQRERN 267
Query: 236 GSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGS----MESLTSS 291
+S SS R G P G +A +L S+ E+ED+ + ++ + S
Sbjct: 268 QASWSSSRRSTSTTGKPSQATGPSANWAKAEQLTTCSSYPSSEDEDKPATDPVLQVVYKS 327
Query: 292 EGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRP---------------------- 329
+G+E E + +A T++ +PN + P
Sbjct: 328 QGKESPGEEFSAEETEETFVKAETEKSDYDTPNYLLSPAAAHRPKSQKCVAYKFRLVVKA 387
Query: 330 -----TKKG--------------RDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAI 370
T G ++ + KG P Q+ KRK LVKE+KAA+TLSAI
Sbjct: 388 DGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNPNPSHQMTKRKRVVLVKERKAAQTLSAI 447
Query: 371 LLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFR 430
LLAFI+TWTPYNIMVLVSTFC CVP TLW LGYWLCYVNST+NP+CYALCN+ FR TF+
Sbjct: 448 LLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTVNPICYALCNRTFRKTFK 507
Query: 431 LLLLCRWDKRR 441
+LLLCRW K++
Sbjct: 508 MLLLCRWKKKK 518
>gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens]
Length = 479
Score = 400 bits (1027), Expect = e-111
Identities = 216/448 (48%), Positives = 283/448 (63%), Gaps = 40/448 (8%)
Query: 24 QVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYT 83
++ FI TG LSL TV GN+LV++S KVN +L+TVNNYFL SLACADLIIG FSMNLYT
Sbjct: 31 EMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYT 90
Query: 84 TYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAA 143
Y++ G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+PL+Y A+RT + A
Sbjct: 91 VYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAG 150
Query: 144 LMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTV 203
LMI AW++SFVLWAPAILFWQ++VG+RTV QC+IQFLS P +TFGTA+AAFYLPV +
Sbjct: 151 LMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVI 210
Query: 204 MCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCR-C 262
M LY I + +R + E P + + + +S + + PPG R
Sbjct: 211 MTVLYIHISLASRSRVHK----HRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREE 266
Query: 263 CRAPRLLQA---------YSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQA 313
R +L +A +++ +E S S T + E P +E + P A
Sbjct: 267 LRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATE-LSTTEATTPAMPA 325
Query: 314 PTKQP----PRSSPNTVKRPTKKGRDR----------AGKGQKPR----------GKEQL 349
P QP P S + ++ TK+ + G +P + Q+
Sbjct: 326 PPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQV 385
Query: 350 AKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYV 409
K++ + +E+K RT+ AILLAFILTWTPYN+MVLV+TFC+ C+P+T+W +GYWLCYV
Sbjct: 386 RKKRQMA-ARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPDTVWSIGYWLCYV 444
Query: 410 NSTINPMCYALCNKAFRDTFRLLLLCRW 437
NSTINP CYALCN F+ TFR LLLC++
Sbjct: 445 NSTINPACYALCNATFKKTFRHLLLCQY 472
>gi|4502817 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 391 bits (1004), Expect = e-109
Identities = 209/452 (46%), Positives = 275/452 (60%), Gaps = 24/452 (5%)
Query: 10 SPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLAC 69
S N L ++V FI + G LSL T+ GN+LV++S KVN L+TVNNYFL SLAC
Sbjct: 8 SNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLAC 67
Query: 70 ADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTR 129
ADLIIG FSMNLYT Y ++G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+
Sbjct: 68 ADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTK 127
Query: 130 PLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT 189
PL+Y KRT + A +MI AW++SF+LWAPAILFWQ++VG RTV G+CYIQF S +T
Sbjct: 128 PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVT 187
Query: 190 FGTAMAAFYLPVTVMCTLYWRIYRETENR----ARELAALQGSETPG-KGGGSSSSSERS 244
FGTA+AAFYLPV +M LYW I R +++R +E A Q +P G + +
Sbjct: 188 FGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNN 247
Query: 245 QPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS---EGEEPGSEVV 301
P ++ E + + R P +E+E ++ + S +S + E E
Sbjct: 248 MPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENT 307
Query: 302 IKMPMVDPEAQAPTKQPPRSSPNTVK----RPTKKGRDRAG-KGQKPRGKEQLAKRKTFS 356
+ + + + + R T K PT + G GQ K+ + RK
Sbjct: 308 VSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVK 367
Query: 357 LVK-----------EKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYW 405
+ K EKK RT+ AILLAFI+TW PYN+MVL++TFC C+P T+W +GYW
Sbjct: 368 MTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYW 427
Query: 406 LCYVNSTINPMCYALCNKAFRDTFRLLLLCRW 437
LCY+NSTINP CYALCN F+ TF+ LL+C +
Sbjct: 428 LCYINSTINPACYALCNATFKKTFKHLLMCHY 459
>gi|54792117 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 391 bits (1004), Expect = e-109
Identities = 209/452 (46%), Positives = 275/452 (60%), Gaps = 24/452 (5%)
Query: 10 SPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLAC 69
S N L ++V FI + G LSL T+ GN+LV++S KVN L+TVNNYFL SLAC
Sbjct: 8 SNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLAC 67
Query: 70 ADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTR 129
ADLIIG FSMNLYT Y ++G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+
Sbjct: 68 ADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTK 127
Query: 130 PLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT 189
PL+Y KRT + A +MI AW++SF+LWAPAILFWQ++VG RTV G+CYIQF S +T
Sbjct: 128 PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVT 187
Query: 190 FGTAMAAFYLPVTVMCTLYWRIYRETENR----ARELAALQGSETPG-KGGGSSSSSERS 244
FGTA+AAFYLPV +M LYW I R +++R +E A Q +P G + +
Sbjct: 188 FGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNN 247
Query: 245 QPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS---EGEEPGSEVV 301
P ++ E + + R P +E+E ++ + S +S + E E
Sbjct: 248 MPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENT 307
Query: 302 IKMPMVDPEAQAPTKQPPRSSPNTVK----RPTKKGRDRAG-KGQKPRGKEQLAKRKTFS 356
+ + + + + R T K PT + G GQ K+ + RK
Sbjct: 308 VSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVK 367
Query: 357 LVK-----------EKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYW 405
+ K EKK RT+ AILLAFI+TW PYN+MVL++TFC C+P T+W +GYW
Sbjct: 368 MTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYW 427
Query: 406 LCYVNSTINPMCYALCNKAFRDTFRLLLLCRW 437
LCY+NSTINP CYALCN F+ TF+ LL+C +
Sbjct: 428 LCYINSTINPACYALCNATFKKTFKHLLMCHY 459
>gi|54792115 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 391 bits (1004), Expect = e-109
Identities = 209/452 (46%), Positives = 275/452 (60%), Gaps = 24/452 (5%)
Query: 10 SPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLAC 69
S N L ++V FI + G LSL T+ GN+LV++S KVN L+TVNNYFL SLAC
Sbjct: 8 SNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLAC 67
Query: 70 ADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTR 129
ADLIIG FSMNLYT Y ++G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+
Sbjct: 68 ADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTK 127
Query: 130 PLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT 189
PL+Y KRT + A +MI AW++SF+LWAPAILFWQ++VG RTV G+CYIQF S +T
Sbjct: 128 PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVT 187
Query: 190 FGTAMAAFYLPVTVMCTLYWRIYRETENR----ARELAALQGSETPG-KGGGSSSSSERS 244
FGTA+AAFYLPV +M LYW I R +++R +E A Q +P G + +
Sbjct: 188 FGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNN 247
Query: 245 QPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS---EGEEPGSEVV 301
P ++ E + + R P +E+E ++ + S +S + E E
Sbjct: 248 MPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENT 307
Query: 302 IKMPMVDPEAQAPTKQPPRSSPNTVK----RPTKKGRDRAG-KGQKPRGKEQLAKRKTFS 356
+ + + + + R T K PT + G GQ K+ + RK
Sbjct: 308 VSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVK 367
Query: 357 LVK-----------EKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYW 405
+ K EKK RT+ AILLAFI+TW PYN+MVL++TFC C+P T+W +GYW
Sbjct: 368 MTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYW 427
Query: 406 LCYVNSTINPMCYALCNKAFRDTFRLLLLCRW 437
LCY+NSTINP CYALCN F+ TF+ LL+C +
Sbjct: 428 LCYINSTINPACYALCNATFKKTFKHLLMCHY 459
>gi|54792113 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 391 bits (1004), Expect = e-109
Identities = 209/452 (46%), Positives = 275/452 (60%), Gaps = 24/452 (5%)
Query: 10 SPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLAC 69
S N L ++V FI + G LSL T+ GN+LV++S KVN L+TVNNYFL SLAC
Sbjct: 8 SNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLAC 67
Query: 70 ADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTR 129
ADLIIG FSMNLYT Y ++G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+
Sbjct: 68 ADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTK 127
Query: 130 PLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT 189
PL+Y KRT + A +MI AW++SF+LWAPAILFWQ++VG RTV G+CYIQF S +T
Sbjct: 128 PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVT 187
Query: 190 FGTAMAAFYLPVTVMCTLYWRIYRETENR----ARELAALQGSETPG-KGGGSSSSSERS 244
FGTA+AAFYLPV +M LYW I R +++R +E A Q +P G + +
Sbjct: 188 FGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNN 247
Query: 245 QPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS---EGEEPGSEVV 301
P ++ E + + R P +E+E ++ + S +S + E E
Sbjct: 248 MPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENT 307
Query: 302 IKMPMVDPEAQAPTKQPPRSSPNTVK----RPTKKGRDRAG-KGQKPRGKEQLAKRKTFS 356
+ + + + + R T K PT + G GQ K+ + RK
Sbjct: 308 VSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVK 367
Query: 357 LVK-----------EKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYW 405
+ K EKK RT+ AILLAFI+TW PYN+MVL++TFC C+P T+W +GYW
Sbjct: 368 MTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYW 427
Query: 406 LCYVNSTINPMCYALCNKAFRDTFRLLLLCRW 437
LCY+NSTINP CYALCN F+ TF+ LL+C +
Sbjct: 428 LCYINSTINPACYALCNATFKKTFKHLLMCHY 459
>gi|54792111 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 391 bits (1004), Expect = e-109
Identities = 209/452 (46%), Positives = 275/452 (60%), Gaps = 24/452 (5%)
Query: 10 SPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLAC 69
S N L ++V FI + G LSL T+ GN+LV++S KVN L+TVNNYFL SLAC
Sbjct: 8 SNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLAC 67
Query: 70 ADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTR 129
ADLIIG FSMNLYT Y ++G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+
Sbjct: 68 ADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTK 127
Query: 130 PLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT 189
PL+Y KRT + A +MI AW++SF+LWAPAILFWQ++VG RTV G+CYIQF S +T
Sbjct: 128 PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVT 187
Query: 190 FGTAMAAFYLPVTVMCTLYWRIYRETENR----ARELAALQGSETPG-KGGGSSSSSERS 244
FGTA+AAFYLPV +M LYW I R +++R +E A Q +P G + +
Sbjct: 188 FGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNN 247
Query: 245 QPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS---EGEEPGSEVV 301
P ++ E + + R P +E+E ++ + S +S + E E
Sbjct: 248 MPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENT 307
Query: 302 IKMPMVDPEAQAPTKQPPRSSPNTVK----RPTKKGRDRAG-KGQKPRGKEQLAKRKTFS 356
+ + + + + R T K PT + G GQ K+ + RK
Sbjct: 308 VSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVK 367
Query: 357 LVK-----------EKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYW 405
+ K EKK RT+ AILLAFI+TW PYN+MVL++TFC C+P T+W +GYW
Sbjct: 368 MTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYW 427
Query: 406 LCYVNSTINPMCYALCNKAFRDTFRLLLLCRW 437
LCY+NSTINP CYALCN F+ TF+ LL+C +
Sbjct: 428 LCYINSTINPACYALCNATFKKTFKHLLMCHY 459
>gi|54792109 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 391 bits (1004), Expect = e-109
Identities = 209/452 (46%), Positives = 275/452 (60%), Gaps = 24/452 (5%)
Query: 10 SPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLAC 69
S N L ++V FI + G LSL T+ GN+LV++S KVN L+TVNNYFL SLAC
Sbjct: 8 SNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLAC 67
Query: 70 ADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTR 129
ADLIIG FSMNLYT Y ++G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+
Sbjct: 68 ADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTK 127
Query: 130 PLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT 189
PL+Y KRT + A +MI AW++SF+LWAPAILFWQ++VG RTV G+CYIQF S +T
Sbjct: 128 PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVT 187
Query: 190 FGTAMAAFYLPVTVMCTLYWRIYRETENR----ARELAALQGSETPG-KGGGSSSSSERS 244
FGTA+AAFYLPV +M LYW I R +++R +E A Q +P G + +
Sbjct: 188 FGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNN 247
Query: 245 QPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS---EGEEPGSEVV 301
P ++ E + + R P +E+E ++ + S +S + E E
Sbjct: 248 MPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENT 307
Query: 302 IKMPMVDPEAQAPTKQPPRSSPNTVK----RPTKKGRDRAG-KGQKPRGKEQLAKRKTFS 356
+ + + + + R T K PT + G GQ K+ + RK
Sbjct: 308 VSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVK 367
Query: 357 LVK-----------EKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYW 405
+ K EKK RT+ AILLAFI+TW PYN+MVL++TFC C+P T+W +GYW
Sbjct: 368 MTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYW 427
Query: 406 LCYVNSTINPMCYALCNKAFRDTFRLLLLCRW 437
LCY+NSTINP CYALCN F+ TF+ LL+C +
Sbjct: 428 LCYINSTINPACYALCNATFKKTFKHLLMCHY 459
>gi|54792107 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 391 bits (1004), Expect = e-109
Identities = 209/452 (46%), Positives = 275/452 (60%), Gaps = 24/452 (5%)
Query: 10 SPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLAC 69
S N L ++V FI + G LSL T+ GN+LV++S KVN L+TVNNYFL SLAC
Sbjct: 8 SNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLAC 67
Query: 70 ADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTR 129
ADLIIG FSMNLYT Y ++G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+
Sbjct: 68 ADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTK 127
Query: 130 PLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT 189
PL+Y KRT + A +MI AW++SF+LWAPAILFWQ++VG RTV G+CYIQF S +T
Sbjct: 128 PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVT 187
Query: 190 FGTAMAAFYLPVTVMCTLYWRIYRETENR----ARELAALQGSETPG-KGGGSSSSSERS 244
FGTA+AAFYLPV +M LYW I R +++R +E A Q +P G + +
Sbjct: 188 FGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNN 247
Query: 245 QPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS---EGEEPGSEVV 301
P ++ E + + R P +E+E ++ + S +S + E E
Sbjct: 248 MPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENT 307
Query: 302 IKMPMVDPEAQAPTKQPPRSSPNTVK----RPTKKGRDRAG-KGQKPRGKEQLAKRKTFS 356
+ + + + + R T K PT + G GQ K+ + RK
Sbjct: 308 VSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVK 367
Query: 357 LVK-----------EKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYW 405
+ K EKK RT+ AILLAFI+TW PYN+MVL++TFC C+P T+W +GYW
Sbjct: 368 MTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYW 427
Query: 406 LCYVNSTINPMCYALCNKAFRDTFRLLLLCRW 437
LCY+NSTINP CYALCN F+ TF+ LL+C +
Sbjct: 428 LCYINSTINPACYALCNATFKKTFKHLLMCHY 459
>gi|54792105 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 391 bits (1004), Expect = e-109
Identities = 209/452 (46%), Positives = 275/452 (60%), Gaps = 24/452 (5%)
Query: 10 SPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLAC 69
S N L ++V FI + G LSL T+ GN+LV++S KVN L+TVNNYFL SLAC
Sbjct: 8 SNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLAC 67
Query: 70 ADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTR 129
ADLIIG FSMNLYT Y ++G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+
Sbjct: 68 ADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTK 127
Query: 130 PLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIIT 189
PL+Y KRT + A +MI AW++SF+LWAPAILFWQ++VG RTV G+CYIQF S +T
Sbjct: 128 PLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVT 187
Query: 190 FGTAMAAFYLPVTVMCTLYWRIYRETENR----ARELAALQGSETPG-KGGGSSSSSERS 244
FGTA+AAFYLPV +M LYW I R +++R +E A Q +P G + +
Sbjct: 188 FGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNN 247
Query: 245 QPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS---EGEEPGSEVV 301
P ++ E + + R P +E+E ++ + S +S + E E
Sbjct: 248 MPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENT 307
Query: 302 IKMPMVDPEAQAPTKQPPRSSPNTVK----RPTKKGRDRAG-KGQKPRGKEQLAKRKTFS 356
+ + + + + R T K PT + G GQ K+ + RK
Sbjct: 308 VSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVK 367
Query: 357 LVK-----------EKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYW 405
+ K EKK RT+ AILLAFI+TW PYN+MVL++TFC C+P T+W +GYW
Sbjct: 368 MTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYW 427
Query: 406 LCYVNSTINPMCYALCNKAFRDTFRLLLLCRW 437
LCY+NSTINP CYALCN F+ TF+ LL+C +
Sbjct: 428 LCYINSTINPACYALCNATFKKTFKHLLMCHY 459
>gi|194018562 histamine receptor H3 [Homo sapiens]
Length = 445
Score = 218 bits (555), Expect = 9e-57
Identities = 131/414 (31%), Positives = 206/414 (49%), Gaps = 27/414 (6%)
Query: 26 AFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTY 85
A + LL +ATV GN LV+++F ++ L+T NN+FLL+LA +D ++G F + LY Y
Sbjct: 35 AVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPY 94
Query: 86 LLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKR-TPRRAAL 144
+L G W G C LWL +DY+ +S N++LIS+DR+ SVTR +SYRA++ RRA
Sbjct: 95 VLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVR 154
Query: 145 MIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVM 204
+ L W+++F+L+ PAIL W+YL G ++ G CY +F + F+ P +
Sbjct: 155 KMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSV 214
Query: 205 CTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCR 264
IY + R R G ++ P A+ SP PPG C C +
Sbjct: 215 TFFNLSIYLNIQRRTRLRL----------DGAREAAGPEPPPEAQPSPPPPPG-CWGCWQ 263
Query: 265 ----APRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPR 320
L Y E E +L G G V P + + +
Sbjct: 264 KGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGG---GGSV------ASPTSSSGSSSRGT 314
Query: 321 SSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTP 380
P ++KR +K A ++ + Q ++ F L +++K A++L+ I+ F L W P
Sbjct: 315 ERPRSLKRGSKPSASSASLEKRMKMVSQSFTQR-FRLSRDRKVAKSLAVIVSIFGLCWAP 373
Query: 381 YNIMVLVSTFCK-DCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLL 433
Y +++++ C CVP+ +E +WL + NS +NP+ Y LC+ +FR F LL
Sbjct: 374 YTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLL 427
>gi|149158709 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 185 bits (469), Expect = 9e-47
Identities = 140/464 (30%), Positives = 212/464 (45%), Gaps = 66/464 (14%)
Query: 30 ITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMG 89
+ + L TV NLLVL + + +L TV N +++SL+ ADLI+G M + YLLM
Sbjct: 32 VVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMS 91
Query: 90 HWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLA 149
W+LG C WL++DYVAS AS+ ++ ++ DRY SV +PL Y RT RA+ I A
Sbjct: 92 KWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGA 151
Query: 150 WLVSFVLWAPAILFWQYLVGERTV-LAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLY 208
W +SF LW IL W + + + +V +C F TA+ FYLP +M Y
Sbjct: 152 WFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTLLMLWFY 210
Query: 209 WRIYRETENRARELAALQGS------------------ETPGKGGGSSSSSERSQPGAEG 250
+IY+ + + S + PGK + + G
Sbjct: 211 AKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGG 270
Query: 251 SPETPPGRCCRCCRAPRLLQAYSWKEEEEED----------------EGSME---SLTSS 291
S P + + ++P +S +++ E D EGS ++ S
Sbjct: 271 SVLKSPSQTPKEMKSP---VVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVAVNRS 327
Query: 292 EG----EEPG------SEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQ 341
G +E G SE+ + D ++ + T S T + KG+ R+G
Sbjct: 328 HGQLKTDEQGLNTHGASEISEDQMLGDSQSFSRT-----DSDTTTETAPGKGKLRSGSNT 382
Query: 342 -----KPRGKEQLAKRKTF----SLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCK 392
K K + + + + +E+KAA+ L I+ AFIL W PY I +V FCK
Sbjct: 383 GLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCK 442
Query: 393 DCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCR 436
+C E L WL Y+NST+NP+ Y LCN+ F+ TF+ +L R
Sbjct: 443 NCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRILHIR 486
>gi|149158706 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 185 bits (469), Expect = 9e-47
Identities = 140/464 (30%), Positives = 212/464 (45%), Gaps = 66/464 (14%)
Query: 30 ITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMG 89
+ + L TV NLLVL + + +L TV N +++SL+ ADLI+G M + YLLM
Sbjct: 32 VVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMS 91
Query: 90 HWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLA 149
W+LG C WL++DYVAS AS+ ++ ++ DRY SV +PL Y RT RA+ I A
Sbjct: 92 KWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGA 151
Query: 150 WLVSFVLWAPAILFWQYLVGERTV-LAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLY 208
W +SF LW IL W + + + +V +C F TA+ FYLP +M Y
Sbjct: 152 WFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTLLMLWFY 210
Query: 209 WRIYRETENRARELAALQGS------------------ETPGKGGGSSSSSERSQPGAEG 250
+IY+ + + S + PGK + + G
Sbjct: 211 AKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGG 270
Query: 251 SPETPPGRCCRCCRAPRLLQAYSWKEEEEED----------------EGSME---SLTSS 291
S P + + ++P +S +++ E D EGS ++ S
Sbjct: 271 SVLKSPSQTPKEMKSP---VVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVAVNRS 327
Query: 292 EG----EEPG------SEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQ 341
G +E G SE+ + D ++ + T S T + KG+ R+G
Sbjct: 328 HGQLKTDEQGLNTHGASEISEDQMLGDSQSFSRT-----DSDTTTETAPGKGKLRSGSNT 382
Query: 342 -----KPRGKEQLAKRKTF----SLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCK 392
K K + + + + +E+KAA+ L I+ AFIL W PY I +V FCK
Sbjct: 383 GLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCK 442
Query: 393 DCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCR 436
+C E L WL Y+NST+NP+ Y LCN+ F+ TF+ +L R
Sbjct: 443 NCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRILHIR 486
>gi|149158704 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 185 bits (469), Expect = 9e-47
Identities = 140/464 (30%), Positives = 212/464 (45%), Gaps = 66/464 (14%)
Query: 30 ITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMG 89
+ + L TV NLLVL + + +L TV N +++SL+ ADLI+G M + YLLM
Sbjct: 32 VVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMS 91
Query: 90 HWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLA 149
W+LG C WL++DYVAS AS+ ++ ++ DRY SV +PL Y RT RA+ I A
Sbjct: 92 KWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGA 151
Query: 150 WLVSFVLWAPAILFWQYLVGERTV-LAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLY 208
W +SF LW IL W + + + +V +C F TA+ FYLP +M Y
Sbjct: 152 WFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTLLMLWFY 210
Query: 209 WRIYRETENRARELAALQGS------------------ETPGKGGGSSSSSERSQPGAEG 250
+IY+ + + S + PGK + + G
Sbjct: 211 AKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGG 270
Query: 251 SPETPPGRCCRCCRAPRLLQAYSWKEEEEED----------------EGSME---SLTSS 291
S P + + ++P +S +++ E D EGS ++ S
Sbjct: 271 SVLKSPSQTPKEMKSP---VVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVAVNRS 327
Query: 292 EG----EEPG------SEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQ 341
G +E G SE+ + D ++ + T S T + KG+ R+G
Sbjct: 328 HGQLKTDEQGLNTHGASEISEDQMLGDSQSFSRT-----DSDTTTETAPGKGKLRSGSNT 382
Query: 342 -----KPRGKEQLAKRKTF----SLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCK 392
K K + + + + +E+KAA+ L I+ AFIL W PY I +V FCK
Sbjct: 383 GLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCK 442
Query: 393 DCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCR 436
+C E L WL Y+NST+NP+ Y LCN+ F+ TF+ +L R
Sbjct: 443 NCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRILHIR 486
>gi|4504491 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 185 bits (469), Expect = 9e-47
Identities = 140/464 (30%), Positives = 212/464 (45%), Gaps = 66/464 (14%)
Query: 30 ITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMG 89
+ + L TV NLLVL + + +L TV N +++SL+ ADLI+G M + YLLM
Sbjct: 32 VVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMS 91
Query: 90 HWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLA 149
W+LG C WL++DYVAS AS+ ++ ++ DRY SV +PL Y RT RA+ I A
Sbjct: 92 KWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGA 151
Query: 150 WLVSFVLWAPAILFWQYLVGERTV-LAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLY 208
W +SF LW IL W + + + +V +C F TA+ FYLP +M Y
Sbjct: 152 WFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTLLMLWFY 210
Query: 209 WRIYRETENRARELAALQGS------------------ETPGKGGGSSSSSERSQPGAEG 250
+IY+ + + S + PGK + + G
Sbjct: 211 AKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGG 270
Query: 251 SPETPPGRCCRCCRAPRLLQAYSWKEEEEED----------------EGSME---SLTSS 291
S P + + ++P +S +++ E D EGS ++ S
Sbjct: 271 SVLKSPSQTPKEMKSP---VVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVAVNRS 327
Query: 292 EG----EEPG------SEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQ 341
G +E G SE+ + D ++ + T S T + KG+ R+G
Sbjct: 328 HGQLKTDEQGLNTHGASEISEDQMLGDSQSFSRT-----DSDTTTETAPGKGKLRSGSNT 382
Query: 342 -----KPRGKEQLAKRKTF----SLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCK 392
K K + + + + +E+KAA+ L I+ AFIL W PY I +V FCK
Sbjct: 383 GLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCK 442
Query: 393 DCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCR 436
+C E L WL Y+NST+NP+ Y LCN+ F+ TF+ +L R
Sbjct: 443 NCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRILHIR 486
>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
sapiens]
Length = 422
Score = 178 bits (451), Expect = 1e-44
Identities = 127/447 (28%), Positives = 210/447 (46%), Gaps = 49/447 (10%)
Query: 2 NTSAPPA---VSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKT 58
NT++PPA N T ++ +QV + G L V GN V+ + + L+
Sbjct: 11 NTTSPPAPFETGGNTTGISDVTVSYQV-ITSLLLGTLIFCAVLGNACVVAAIALERSLQN 69
Query: 59 VNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLL 118
V NY + SLA DL++ + + Y ++ W LG + CDL++ALD + +S+++L
Sbjct: 70 VANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCA 129
Query: 119 ISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQC 178
I+ DRY+++T P+ Y KRTPRRAA +I L WL+ F++ P +L W+ E C
Sbjct: 130 IALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWR--TPEDRSDPDAC 187
Query: 179 YIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRAREL---AALQGSETPGKGG 235
I T + AFY+P+ +M LY RI+R R R+ G++T G
Sbjct: 188 TIS--KDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT-RHGA 244
Query: 236 GSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSS--EG 293
+ ++S G GS +W+ E G + +G
Sbjct: 245 SPAPQPKKSVNGESGS--------------------RNWRLGVESKAGGALCANGAVRQG 284
Query: 294 EEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAK-R 352
++ + VI++ V +S + P++ G R E+ A+ +
Sbjct: 285 DDGAALEVIEVHRVG------------NSKEHLPLPSEAGPTPCAPASFERKNERNAEAK 332
Query: 353 KTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDC--VPETLWELGYWLCYVN 410
+ +L +E+K +TL I+ FIL W P+ I+ LV FC+ +P L + WL Y N
Sbjct: 333 RKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSN 392
Query: 411 STINPMCYALCNKAFRDTFRLLLLCRW 437
S +NP+ YA NK F++ F+ ++ C++
Sbjct: 393 SLLNPVIYAYFNKDFQNAFKKIIKCKF 419
>gi|194353970 alpha-2A-adrenergic receptor [Homo sapiens]
Length = 465
Score = 169 bits (428), Expect = 5e-42
Identities = 119/430 (27%), Positives = 191/430 (44%), Gaps = 43/430 (10%)
Query: 33 GLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWA 92
GLL L TV GN+LV+I+ + LK N FL+SLA AD+++ T + +MG+W
Sbjct: 56 GLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWY 115
Query: 93 LGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLV 152
G C+++LALD + +S+++L IS DRY+S+T+ + Y KRTPRR +I W++
Sbjct: 116 FGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVI 175
Query: 153 SFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIY 212
S V+ P ++ + G + + Q + + +F+ P +M +Y RIY
Sbjct: 176 SAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIY 235
Query: 213 RETENRARELAALQGSE--------------------TPGKGGGSSSSSERSQPGAEGSP 252
+ + R R + +G + + G GG + GA G P
Sbjct: 236 QIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEP 295
Query: 253 ETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQ 312
P G PR A +E D P + + V P
Sbjct: 296 -APAG--------PRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDS 346
Query: 313 APTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILL 372
P + P + T + R A K + RG++ KR TF L+ ++
Sbjct: 347 LPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTF----------VLAVVIG 396
Query: 373 AFILTWTPYNI-MVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRL 431
F++ W P+ L + C VP TL++ +W Y NS++NP+ Y + N FR F+
Sbjct: 397 VFVVCWFPFFFTYTLTAVGCS--VPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFK- 453
Query: 432 LLLCRWDKRR 441
+LCR D++R
Sbjct: 454 KILCRGDRKR 463
>gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]
Length = 450
Score = 161 bits (408), Expect = 1e-39
Identities = 119/445 (26%), Positives = 200/445 (44%), Gaps = 35/445 (7%)
Query: 26 AFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTY 85
A I L L T+ GN LV+++ + L+ N FL+SLA AD+++ T +
Sbjct: 13 AAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLAN 72
Query: 86 LLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALM 145
L+G+W C+++LALD + +S+++L IS DRY++V+R L Y +KRTPRR +
Sbjct: 73 ELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCI 132
Query: 146 IGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMC 205
I WL++ V+ P ++ Y + G+ + + +++ +F+ P +M
Sbjct: 133 ILTVWLIAAVISLPPLI---YKGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMI 189
Query: 206 TLYWRIYRETENRARELAALQGSETPGKG---------GGSSSSSE-------------- 242
+Y RIY + R +G PG+G GG+ +S++
Sbjct: 190 LVYLRIYLIAKRSNRRGPRAKGG--PGQGESKQPRPDHGGALASAKLPALASVASAREVN 247
Query: 243 --RSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV 300
G + ETP R S + ++E G+ + E EE E
Sbjct: 248 GHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEEEEEEEEE 307
Query: 301 VIKMPMVDPEAQAPTKQPPRSSPNTVK-RPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVK 359
P P + A PP P + T +G+ G+G G + +R L +
Sbjct: 308 EECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRRA--QLTR 365
Query: 360 EKKAARTLSAILLAFILTWTPYNIMVLVSTFC-KDC-VPETLWELGYWLCYVNSTINPMC 417
EK+ L+ ++ F+L W P+ + C K C VP L++ +W+ Y NS++NP+
Sbjct: 366 EKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNPVI 425
Query: 418 YALCNKAFRDTFRLLLLCRWDKRRW 442
Y + N+ FR FR +L W + W
Sbjct: 426 YTIFNQDFRRAFRRILCRPWTQTAW 450
>gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens]
Length = 462
Score = 157 bits (397), Expect = 2e-38
Identities = 115/425 (27%), Positives = 201/425 (47%), Gaps = 33/425 (7%)
Query: 25 VAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTT 84
VA + G L + TV GN+LV+I+ + L+ N FL+SLA AD+++ T M
Sbjct: 51 VAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLA 110
Query: 85 YLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAAL 144
LM +W G + C ++LALD + +S+++L IS DRY+SVT+ + Y KRTPRR
Sbjct: 111 NELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKA 170
Query: 145 MIGLAWLVSFVL-WAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTV 203
I WL+S V+ + P + ++ G QC + + I++ + + +F+ P +
Sbjct: 171 TIVAVWLISAVISFPPLVSLYRQPDG---AAYPQCGLNDETWYILS--SCIGSFFAPCLI 225
Query: 204 MCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCC--- 260
M +Y RIYR + R R L+ + P G+S ++E A G+ E G C
Sbjct: 226 MGLVYARIYRVAKLRTRTLSEKRAPVGP---DGASPTTENGLGAAAGAGEN--GHCAPPP 280
Query: 261 -------RCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQA 313
A R + + + G+ ++G+ G + +
Sbjct: 281 ADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPG 340
Query: 314 PTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLA 373
P + R+S +V+ + R R + + +RK + +EK+ L+ ++
Sbjct: 341 PGGRLSRASSRSVEFFLSRRR---------RARSSVCRRKV-AQAREKRFTFVLAVVMGV 390
Query: 374 FILTWTPYNIMVLVSTFCKDC--VPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRL 431
F+L W P+ + C++ VP L++ +W+ Y NS++NP+ Y + N+ FR +F+
Sbjct: 391 FVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKH 450
Query: 432 LLLCR 436
+L R
Sbjct: 451 ILFRR 455
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 155 bits (393), Expect = 6e-38
Identities = 116/414 (28%), Positives = 182/414 (43%), Gaps = 78/414 (18%)
Query: 22 PWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNL 81
PW+V + + L++LAT N V+ + +L T NY + SLA DL++ M +
Sbjct: 47 PWKVLLV-MLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPI 105
Query: 82 YTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRR 141
T Y + G W LG + CD WL+ D AS+++L +I+ DRY+++T + Y AKRTP+R
Sbjct: 106 STMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKR 165
Query: 142 AALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPV 201
AA+MI L W+ S + P FW+ E V +C + + T + + AFY P
Sbjct: 166 AAVMIALVWVFSISISLPP-FFWRQAKAEEEV--SECVVN-TDHILYTVYSTVGAFYFPT 221
Query: 202 TVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCR 261
++ LY RIY E +R + +TP + G R
Sbjct: 222 LLLIALYGRIYVEARSRILK-------QTPNRTGK------------------------R 250
Query: 262 CCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRS 321
RA + + GS S+TS + ++P V E+
Sbjct: 251 LTRAQLI----------TDSPGSTSSVTS---------INSRVPDVPSES---------G 282
Query: 322 SPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPY 381
SP V + + D + +K + KT ++ L AFI+ W P+
Sbjct: 283 SPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGII------------LGAFIVCWLPF 330
Query: 382 NIMVLVSTFCKDC--VPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLL 433
I+ LV CKD +++ WL Y+NS INP+ Y + N+ F+ F L+
Sbjct: 331 FIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLI 384
>gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]
Length = 443
Score = 146 bits (369), Expect = 3e-35
Identities = 115/422 (27%), Positives = 180/422 (42%), Gaps = 41/422 (9%)
Query: 34 LLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWAL 93
LL V GN+LV ++ L+T NY ++SLA ADL++ T M ++G W
Sbjct: 43 LLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKF 102
Query: 94 GTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAK-RTPRRAALMIGLAWLV 152
+ CD+++ LD + AS++NL IS DRY +V P+ Y + + RR +MI + W++
Sbjct: 103 SRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVL 162
Query: 153 SFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIY 212
SF + P L G +C I + P +++ +FY+P V +Y +IY
Sbjct: 163 SFTISCP------LLFGLNNADQNECII---ANPAFVVYSSIVSFYVPFIVTLLVYIKIY 213
Query: 213 RETENRARELAALQGS-------ETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRA 265
R + + + S P KG + + S + P R A
Sbjct: 214 IVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAA 273
Query: 266 PRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNT 325
R E ME L+S+ E I P+ S+P++
Sbjct: 274 RR------------AQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDS 321
Query: 326 VKRPTKKGRDRAGK--------GQKPRGKEQLA----KRKTFSLVKEKKAARTLSAILLA 373
+P K G + P GK + + R+ S KEKKA + L+ +L
Sbjct: 322 PAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGV 381
Query: 374 FILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLL 433
FI+ W P+ I +++ C +P L+ WL YVNS +NP+ Y N FR F +L
Sbjct: 382 FIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKIL 441
Query: 434 LC 435
C
Sbjct: 442 HC 443
>gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]
Length = 414
Score = 146 bits (368), Expect = 4e-35
Identities = 112/415 (26%), Positives = 176/415 (42%), Gaps = 56/415 (13%)
Query: 34 LLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWAL 93
LL V GN+LV ++ L+T NY ++SLA ADL++ T M ++G W
Sbjct: 43 LLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKF 102
Query: 94 GTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAK-RTPRRAALMIGLAWLV 152
+ CD+++ LD + AS++NL IS DRY +V P+ Y + + RR +MI + W++
Sbjct: 103 SRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVL 162
Query: 153 SFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIY 212
SF + P L G +C I + P +++ +FY+P V +Y +IY
Sbjct: 163 SFTISCP------LLFGLNNADQNECII---ANPAFVVYSSIVSFYVPFIVTLLVYIKIY 213
Query: 213 RETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAY 272
R + + +++RS P R RA L
Sbjct: 214 IVLRRRRKRV-----------------NTKRSSRAFRAHLRAPLKEAAR--RAQEL---- 250
Query: 273 SWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKK 332
ME L+S+ E I P+ S+P++ +P K
Sbjct: 251 -----------EMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKN 299
Query: 333 GRDRAGK--------GQKPRGKEQLA----KRKTFSLVKEKKAARTLSAILLAFILTWTP 380
G + P GK + + R+ S KEKKA + L+ +L FI+ W P
Sbjct: 300 GHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLP 359
Query: 381 YNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLC 435
+ I +++ C +P L+ WL YVNS +NP+ Y N FR F +L C
Sbjct: 360 FFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 414
>gi|32483397 dopamine receptor D4 [Homo sapiens]
Length = 419
Score = 143 bits (361), Expect = 3e-34
Identities = 121/433 (27%), Positives = 178/433 (41%), Gaps = 44/433 (10%)
Query: 16 LAPGKGPWQVAFIGITTGL-------------LSLATVTGNLLVLISFKVNTELKTVNNY 62
L G+GP A G + GL L A + GN LV +S L+T N
Sbjct: 12 LLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNS 71
Query: 63 FLLSLACADLIIGTFSMNLYT-TYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISF 121
F++SLA ADL++ + L+ + + G W L CD +A+D + AS+ NL IS
Sbjct: 72 FIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISV 131
Query: 122 DRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQ 181
DR+ +V PL Y + RR L+IG WL+S + AP L G V +
Sbjct: 132 DRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPV------LCGLNDVRGRDPAVC 185
Query: 182 FLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSS 241
L +++ +F+LP +M LYW +R + A P + G S
Sbjct: 186 RLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPS 245
Query: 242 ERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVV 301
P A P+ P G C AP L + + + S + G +
Sbjct: 246 --PTPPAPRLPQDPCGPDC-APPAPGLPRGPCGPD-------CAPAAPSLPQDPCGPDCA 295
Query: 302 IKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEK 361
P + P+ PP + P + R + K G +E+
Sbjct: 296 PPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITG-------------RER 342
Query: 362 KAARTLSAILLAFILTWTPYNIMVLVSTFCKDC-VPETLWELGYWLCYVNSTINPMCYAL 420
KA R L ++ AF+L WTP+ ++ + C C VP L WL YVNS +NP+ Y +
Sbjct: 343 KAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTV 402
Query: 421 CNKAFRDTFRLLL 433
N FR+ FR L
Sbjct: 403 FNAEFRNVFRKAL 415
>gi|89191861 dopamine receptor D3 isoform a [Homo sapiens]
Length = 400
Score = 136 bits (342), Expect = 5e-32
Identities = 119/422 (28%), Positives = 187/422 (44%), Gaps = 63/422 (14%)
Query: 26 AFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTY 85
A+ ++ L LA V GN LV ++ L+T NY ++SLA ADL++ T M + Y
Sbjct: 30 AYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMP-WVVY 88
Query: 86 LLM--GHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYR---AKRTPR 140
L + G W + CD+++ LD + AS++NL IS DRY +V P+ Y+ + + R
Sbjct: 89 LEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCR 148
Query: 141 RAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLP 200
R ALMI W+++F + P +LF G+ TV + +S P +++ +FYLP
Sbjct: 149 RVALMITAVWVLAFAVSCP-LLFGFNTTGDPTVCS-------ISNPDFVIYSSVVSFYLP 200
Query: 201 VTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETP-PGRC 259
V +Y RIY + R R+ + +S +PG +P P
Sbjct: 201 FGVTVLVYARIYVVLKQRRRKRILTR----------QNSQCNSVRPGFPQQTLSPDPAHL 250
Query: 260 CRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPP 319
L + YS ++ +L +E G E + E + P
Sbjct: 251 -------ELKRYYSICQD--------TALGGPGFQERGGE-------LKREEKTRNSLSP 288
Query: 320 RSSPNTVKRPTKKGRDRAGKGQK-----PRGKEQLAKRKTFSLVKEKKAARTLSAILLAF 374
+P K R K PRG ++EKKA + ++ +L AF
Sbjct: 289 TIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVP----------LREKKATQMVAIVLGAF 338
Query: 375 ILTWTPYNIMVLVSTFCKDC-VPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLL 433
I+ W P+ + +++T C+ C V L+ WL YVNS +NP+ Y N FR F +L
Sbjct: 339 IVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKIL 398
Query: 434 LC 435
C
Sbjct: 399 SC 400
>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
sapiens]
Length = 366
Score = 132 bits (331), Expect = 9e-31
Identities = 103/412 (25%), Positives = 182/412 (44%), Gaps = 75/412 (18%)
Query: 28 IGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLL 87
+ +T L+L T T N LV+ + V +L NY + SLA D ++ M Y++
Sbjct: 26 VSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIV 85
Query: 88 MGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIG 147
W +G + CD+WL++D S+++L I+ DRY ++T + Y KRTP+ A +MI
Sbjct: 86 RESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMIT 145
Query: 148 LAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTL 207
+ W++S + P LFW++ + T +C I+ + T + AFY+P+ ++ L
Sbjct: 146 IVWIISVFISMPP-LFWRH---QGTSRDDECIIKH-DHIVSTIYSTFGAFYIPLALILIL 200
Query: 208 YWRIYR--ETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRA 265
Y++IYR +T R+ + + E G+
Sbjct: 201 YYKIYRAAKTLYHKRQASRIAKEEVNGQ-------------------------------- 228
Query: 266 PRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNT 325
LL E E S +S+++S V++ + DP S+ +
Sbjct: 229 -VLL---------ESGEKSTKSVSTS--------YVLEKSLSDPSTDF---DKIHSTVRS 267
Query: 326 VKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMV 385
++ K +++ + QK G + T L+ L A ++ ++ P+ +
Sbjct: 268 LRSEFK--HEKSWRRQKISGTRERKAATTLGLI--------LGAFVICWL----PFFVKE 313
Query: 386 LVSTFCKDC-VPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCR 436
LV C C + E + WL Y+NS INP+ Y + N+ F+ F+ L+ CR
Sbjct: 314 LVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCR 365
>gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo
sapiens]
Length = 365
Score = 130 bits (326), Expect = 3e-30
Identities = 105/411 (25%), Positives = 169/411 (41%), Gaps = 75/411 (18%)
Query: 28 IGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLL 87
I +T +++ T NL V+++ +L NY + SLA DL++ M L Y++
Sbjct: 25 ICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIV 84
Query: 88 MGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIG 147
M W LG C++WL++D S+++L +I+ DRY+++T + Y KRT +RAALMI
Sbjct: 85 MDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMIL 144
Query: 148 LAWLVSFVLWAPAILFWQYLVGERTVL--AGQCYIQFLSQPIITFGTAMAAFYLPVTVMC 205
W +S + P LFW+ R + QC IQ I T + + AFY+P+T++
Sbjct: 145 TVWTISIFISMPP-LFWR---SHRRLSPPPSQCTIQH-DHVIYTIYSTLGAFYIPLTLIL 199
Query: 206 TLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRA 265
LY+RIY ++ + K G S S RS
Sbjct: 200 ILYYRIYHAAKSLYQ------------KRGSSRHLSNRS--------------------- 226
Query: 266 PRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNT 325
T S+ ++ + D PT + + +
Sbjct: 227 -----------------------TDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASI 263
Query: 326 VKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMV 385
P D G+ Q+ + + L+ L A +L +W P+ I
Sbjct: 264 RIPPFDNDLDHPGERQQISSTRERKAARILGLI--------LGAFIL----SWLPFFIKE 311
Query: 386 LVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCR 436
L+ V + + WL YVNS INP+ Y N+ F+ F+ L+ CR
Sbjct: 312 LIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCR 362
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 128 bits (321), Expect = 1e-29
Identities = 91/271 (33%), Positives = 132/271 (48%), Gaps = 14/271 (5%)
Query: 7 PAVSPNITVLAPGKG-PWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLL 65
P ++PN + G PW+ A G L LATV GNLLV+++ L+T+ N F+
Sbjct: 18 PTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVT 77
Query: 66 SLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYF 125
SLA ADL++G + T L GHW LG C+LW ++D + AS+ L ++ DRY
Sbjct: 78 SLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYL 137
Query: 126 SVTRPLSYRAKRTPRRAALMIGLAWLVS-FVLWAPAILFWQYLVG-----ERTVLAGQCY 179
+VT PL Y A T R A + L W+VS V +AP + W + VG +R +C
Sbjct: 138 AVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQW-WRVGADAEAQRCHSNPRCC 196
Query: 180 IQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSS 239
+ P + +++ +FYLP+ VM +Y R++ + R L G P + + S
Sbjct: 197 AFASNMPYVLLSSSV-SFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPS 255
Query: 240 SSERSQP-GAEGSPETPPGRCCRCCRAPRLL 269
S P G PE P C R P L
Sbjct: 256 RSLAPAPVGTCAPPEGVPA----CGRRPARL 282
Score = 45.4 bits (106), Expect = 1e-04
Identities = 43/143 (30%), Positives = 59/143 (41%), Gaps = 15/143 (10%)
Query: 314 PTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSL-VKEKKAARTLSAILL 372
P + PP S + P G P G +R L ++E +A TL I+
Sbjct: 247 PEESPPAPSRSLAPAPV-------GTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMG 299
Query: 373 AFILTWTPYNIM-VLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRL 431
F L W P+ + VL + VP + WL Y NS NP+ Y + FR FR
Sbjct: 300 TFTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCR-SPDFRSAFR- 357
Query: 432 LLLCRWDKRRWRKIPKRPGSVHR 454
LLCR R++P P + R
Sbjct: 358 RLLCRCG----RRLPPEPCAAAR 376
>gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo
sapiens]
Length = 458
Score = 126 bits (316), Expect = 5e-29
Identities = 105/424 (24%), Positives = 170/424 (40%), Gaps = 100/424 (23%)
Query: 34 LLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGH-WA 92
++ + T+ GN+LV+++ + +L NYFL+SLA AD+++G M L +L + W
Sbjct: 62 IIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWP 121
Query: 93 LGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLV 152
L C +W++LD + S AS+M+L IS DRY ++ P+ + + +A + I + W +
Sbjct: 122 LPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAI 181
Query: 153 SFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIY 212
S + P + L E V L+ P + AF++P+T+M Y
Sbjct: 182 SIGVSVPIPVIG--LRDEEKVFVNNTTC-VLNDPNFVLIGSFVAFFIPLTIMVITYCLTI 238
Query: 213 RETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRC---CRCCRAPRLL 269
+A L G E PPG +CC
Sbjct: 239 YVLRRQALML-------------------------LHGHTEEPPGLSLDFLKCC------ 267
Query: 270 QAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRP 329
K E+E S P N +R
Sbjct: 268 -----KRNTAEEENSAN--------------------------------PNQDQNARRRK 290
Query: 330 TKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVST 389
K+ ++PRG Q ++ E+KA++ L + F++ W P+ I ++S
Sbjct: 291 KKE--------RRPRGTMQ-------AINNERKASKVLGIVFFVFLIMWCPFFITNILSV 335
Query: 390 FC-KDC---VPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKI 445
C K C + E L + W+ YV S INP+ Y L NK +R F L C + K+
Sbjct: 336 LCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNY------KV 389
Query: 446 PKRP 449
K+P
Sbjct: 390 EKKP 393
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,673,636
Number of Sequences: 37866
Number of extensions: 962248
Number of successful extensions: 9924
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 555
Number of HSP's successfully gapped in prelim test: 369
Number of HSP's that attempted gapping in prelim test: 7918
Number of HSP's gapped (non-prelim): 1802
length of query: 460
length of database: 18,247,518
effective HSP length: 106
effective length of query: 354
effective length of database: 14,233,722
effective search space: 5038737588
effective search space used: 5038737588
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.