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Search of human proteins with 34850061
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34850061 superiorcervical ganglia, neural specific 10 [Homo
sapiens]
(179 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34850061 superiorcervical ganglia, neural specific 10 [Homo s... 345 2e-95
gi|14670375 SCG10-like-protein [Homo sapiens] 249 1e-66
gi|21361947 stathmin-like 4 [Homo sapiens] 206 7e-54
gi|44890052 stathmin 1 isoform a [Homo sapiens] 190 5e-49
gi|44890050 stathmin 1 isoform a [Homo sapiens] 190 5e-49
gi|5031851 stathmin 1 isoform a [Homo sapiens] 190 5e-49
gi|224451142 stathmin 1 isoform b [Homo sapiens] 174 4e-44
gi|225579095 S-phase cyclin A-associated protein in the ER isofo... 45 3e-05
gi|225579092 S-phase cyclin A-associated protein in the ER isofo... 45 3e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 45 4e-05
gi|148746195 trichohyalin [Homo sapiens] 44 7e-05
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 44 7e-05
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 43 1e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 43 1e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 43 1e-04
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 43 2e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 43 2e-04
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 42 2e-04
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 42 2e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 2e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 42 3e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 42 3e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 42 3e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 42 3e-04
gi|34878777 ring finger protein 20 [Homo sapiens] 42 3e-04
gi|4505257 moesin [Homo sapiens] 42 4e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 42 4e-04
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 41 5e-04
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 41 5e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 41 5e-04
>gi|34850061 superiorcervical ganglia, neural specific 10 [Homo
sapiens]
Length = 179
Score = 345 bits (884), Expect = 2e-95
Identities = 179/179 (100%), Positives = 179/179 (100%)
Query: 1 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP 60
MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP
Sbjct: 1 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP 60
Query: 61 PSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKA 120
PSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKA
Sbjct: 61 PSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKA 120
Query: 121 LEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG 179
LEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG
Sbjct: 121 LEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG 179
>gi|14670375 SCG10-like-protein [Homo sapiens]
Length = 180
Score = 249 bits (635), Expect = 1e-66
Identities = 131/180 (72%), Positives = 151/180 (83%), Gaps = 1/180 (0%)
Query: 1 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP 60
MA T AYKEKMKELS+LSLICSCFY +P +Y Y DMEVKQ++KRASGQ+FE+ILK
Sbjct: 1 MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKS 60
Query: 61 PSPIS-EAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQK 119
PS +S E+P + PKKKD SLEE+QK+LEAAEERRK+QEAQVLKQLAE+REHEREVL K
Sbjct: 61 PSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHK 120
Query: 120 ALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG 179
ALEENNNFS+ AEEKL KME KE REA+LAA+ ERL+EKE HAAEVRRNKE + E+SG
Sbjct: 121 ALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG 180
>gi|21361947 stathmin-like 4 [Homo sapiens]
Length = 216
Score = 206 bits (525), Expect = 7e-54
Identities = 116/214 (54%), Positives = 141/214 (65%), Gaps = 39/214 (18%)
Query: 4 TAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------------------- 38
T AYKEKMKEL ++SL CSCF +P N + Y Y+
Sbjct: 2 TLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEGWCGRQCRRKDESQRKDSADWRERR 61
Query: 39 --------------DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEI 84
DMEV ++NK SGQ+FE+ILKPPS + P+++D SLEEI
Sbjct: 62 AQADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVPEFNASLPRRRDPSLEEI 121
Query: 85 QKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKE 144
QKKLEAAEERRK QEA++LK LAEKREHEREV+QKA+EENNNF KMA+EKL KME KE
Sbjct: 122 QKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKE 181
Query: 145 NREANLAAIIERLQEKERHAAEVRRNKELQVELS 178
NREA+LAA++ERLQEK++HA EVR+NKEL+ E S
Sbjct: 182 NREAHLAAMLERLQEKDKHAEEVRKNKELKEEAS 215
>gi|44890052 stathmin 1 isoform a [Homo sapiens]
Length = 149
Score = 190 bits (483), Expect = 5e-49
Identities = 100/134 (74%), Positives = 114/134 (85%)
Query: 39 DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQ 98
D++VK++ KRASGQAFELIL P S S L+ PKKKDLSLEEIQKKLEAAEERRKS
Sbjct: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSH 64
Query: 99 EAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQ 158
EA+VLKQLAEKREHE+EVLQKA+EENNNFSKMAEEKL KME KENREA +AA +ERL+
Sbjct: 65 EAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLR 124
Query: 159 EKERHAAEVRRNKE 172
EK++H EVR+NKE
Sbjct: 125 EKDKHIEEVRKNKE 138
>gi|44890050 stathmin 1 isoform a [Homo sapiens]
Length = 149
Score = 190 bits (483), Expect = 5e-49
Identities = 100/134 (74%), Positives = 114/134 (85%)
Query: 39 DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQ 98
D++VK++ KRASGQAFELIL P S S L+ PKKKDLSLEEIQKKLEAAEERRKS
Sbjct: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSH 64
Query: 99 EAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQ 158
EA+VLKQLAEKREHE+EVLQKA+EENNNFSKMAEEKL KME KENREA +AA +ERL+
Sbjct: 65 EAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLR 124
Query: 159 EKERHAAEVRRNKE 172
EK++H EVR+NKE
Sbjct: 125 EKDKHIEEVRKNKE 138
>gi|5031851 stathmin 1 isoform a [Homo sapiens]
Length = 149
Score = 190 bits (483), Expect = 5e-49
Identities = 100/134 (74%), Positives = 114/134 (85%)
Query: 39 DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQ 98
D++VK++ KRASGQAFELIL P S S L+ PKKKDLSLEEIQKKLEAAEERRKS
Sbjct: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSH 64
Query: 99 EAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQ 158
EA+VLKQLAEKREHE+EVLQKA+EENNNFSKMAEEKL KME KENREA +AA +ERL+
Sbjct: 65 EAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLR 124
Query: 159 EKERHAAEVRRNKE 172
EK++H EVR+NKE
Sbjct: 125 EKDKHIEEVRKNKE 138
>gi|224451142 stathmin 1 isoform b [Homo sapiens]
Length = 174
Score = 174 bits (441), Expect = 4e-44
Identities = 93/122 (76%), Positives = 104/122 (85%)
Query: 39 DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQ 98
D++VK++ KRASGQAFELIL P S S L+ PKKKDLSLEEIQKKLEAAEERRKS
Sbjct: 5 DIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSH 64
Query: 99 EAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQ 158
EA+VLKQLAEKREHE+EVLQKA+EENNNFSKMAEEKL KME KENREA +AA +ERL+
Sbjct: 65 EAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLR 124
Query: 159 EK 160
EK
Sbjct: 125 EK 126
>gi|225579095 S-phase cyclin A-associated protein in the ER isoform
b [Homo sapiens]
Length = 1154
Score = 45.1 bits (105), Expect = 3e-05
Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 12/126 (9%)
Query: 42 VKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQ 101
V++ R G + K SP + RT+A KKK EE Q K + E+ + ++
Sbjct: 267 VEEEPARPPGHGIHMHEKLSSPSRK--RTIAESKKKH---EEKQMKAQQLREKLREEKTL 321
Query: 102 VLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKE 161
L++L E+ + R+ ++ L++ +M EEKL+ + RE L AI+++ QE+E
Sbjct: 322 KLQKLLEREKDVRKWKEELLDQRR---RMMEEKLL----HAEFKREVQLQAIVKKAQEEE 374
Query: 162 RHAAEV 167
E+
Sbjct: 375 AKVNEI 380
Score = 38.5 bits (88), Expect = 0.003
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 26/116 (22%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EE Q + EA +ER+++ E AE++ E+L K E+ + +EK + +
Sbjct: 418 EEKQARDEAVQERKRALE-------AERQARVEELLMKRKEQEARIEQQRQEKEKAREDA 470
Query: 142 IKE---NREANLAAI-------IERLQEK---------ERHAAEVRRNKELQVELS 178
+E +RE LAA+ +E LQ+K RH ++ + KE ELS
Sbjct: 471 ARERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELS 526
Score = 32.0 bits (71), Expect = 0.29
Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 16/110 (14%)
Query: 76 KKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKL 135
K+++ L+ I KK A EE K E + L E + +VL K E +++ EE+
Sbjct: 358 KREVQLQAIVKK--AQEEEAKVNEIAFINTL-EAQNKRHDVLSKLKEYEQRLNELQEERQ 414
Query: 136 ILKMEQ-------------IKENREANLAAIIERLQEKERHAAEVRRNKE 172
+ E+ ++ R+A + ++ + +E+E + R+ KE
Sbjct: 415 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKE 464
Score = 27.7 bits (60), Expect = 5.5
Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFS 128
E + KK E A+ K+ E + +AE+ + RE+ EENN+ +
Sbjct: 174 EVLAKKEELADRLEKANEEAIASAIAEEEQLTREI---EAEENNDIN 217
>gi|225579092 S-phase cyclin A-associated protein in the ER isoform
a [Homo sapiens]
Length = 1400
Score = 45.1 bits (105), Expect = 3e-05
Identities = 36/126 (28%), Positives = 63/126 (50%), Gaps = 12/126 (9%)
Query: 42 VKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQ 101
V++ R G + K SP + RT+A KKK EE Q K + E+ + ++
Sbjct: 513 VEEEPARPPGHGIHMHEKLSSPSRK--RTIAESKKKH---EEKQMKAQQLREKLREEKTL 567
Query: 102 VLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKE 161
L++L E+ + R+ ++ L++ +M EEKL+ + RE L AI+++ QE+E
Sbjct: 568 KLQKLLEREKDVRKWKEELLDQRR---RMMEEKLL----HAEFKREVQLQAIVKKAQEEE 620
Query: 162 RHAAEV 167
E+
Sbjct: 621 AKVNEI 626
Score = 38.5 bits (88), Expect = 0.003
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 26/116 (22%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EE Q + EA +ER+++ E AE++ E+L K E+ + +EK + +
Sbjct: 664 EEKQARDEAVQERKRALE-------AERQARVEELLMKRKEQEARIEQQRQEKEKAREDA 716
Query: 142 IKE---NREANLAAI-------IERLQEK---------ERHAAEVRRNKELQVELS 178
+E +RE LAA+ +E LQ+K RH ++ + KE ELS
Sbjct: 717 ARERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELS 772
Score = 32.0 bits (71), Expect = 0.29
Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 16/110 (14%)
Query: 76 KKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKL 135
K+++ L+ I KK A EE K E + L E + +VL K E +++ EE+
Sbjct: 604 KREVQLQAIVKK--AQEEEAKVNEIAFINTL-EAQNKRHDVLSKLKEYEQRLNELQEERQ 660
Query: 136 ILKMEQ-------------IKENREANLAAIIERLQEKERHAAEVRRNKE 172
+ E+ ++ R+A + ++ + +E+E + R+ KE
Sbjct: 661 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKE 710
Score = 27.7 bits (60), Expect = 5.5
Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFS 128
E + KK E A+ K+ E + +AE+ + RE+ EENN+ +
Sbjct: 420 EVLAKKEELADRLEKANEEAIASAIAEEEQLTREI---EAEENNDIN 463
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 44.7 bits (104), Expect = 4e-05
Identities = 35/115 (30%), Positives = 62/115 (53%), Gaps = 14/115 (12%)
Query: 52 QAFELILKPPSPISEAPRTLASPKKK----DLSLEEIQKKLEAAEERRKSQEAQVLKQLA 107
+A E IL + + L + KK+ +LS++ +++L+A E+R +S+ A L +L
Sbjct: 1582 EAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELK 1641
Query: 108 EKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKER 162
K E + ++K L S+M E K EQ K+ E++L+ + +LQE+ER
Sbjct: 1642 RKAEQKIAAIKKQL-----LSQMEE-----KEEQYKKGTESHLSELNTKLQERER 1686
Score = 39.3 bits (90), Expect = 0.002
Identities = 35/142 (24%), Positives = 73/142 (51%), Gaps = 12/142 (8%)
Query: 40 MEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDL-SLEEIQKK----LEAAEER 94
+E+ Q K+ + + E+ + IS+A L + +K+ + SL E+ ++ + + E+
Sbjct: 990 LELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEK 1049
Query: 95 RKSQEAQVLK-----QLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREAN 149
+ +Q+A+ L+ QL EK + E+ QK L +M +E LK E +K+ +
Sbjct: 1050 KLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQ--DTT 1107
Query: 150 LAAIIERLQEKERHAAEVRRNK 171
L + E+L++K H + +++
Sbjct: 1108 LNELQEQLKQKSAHVNSLAQDE 1129
Score = 33.5 bits (75), Expect = 0.100
Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 29/162 (17%)
Query: 41 EVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQK-------------- 86
E K+ ++RA+ + E L EA R L + + D ++ I+K
Sbjct: 403 EQKEKSERAAFEELEKALSTAQKTEEARRKLKA--EMDEQIKTIEKTSEEERISLQQELS 460
Query: 87 --KLEAAEERRKSQEAQVLK-------QLAEKREHEREVLQKALEENNNFSKMAEEKL-- 135
K E + +KS E Q+ K +LA K + + LQ E K+A EK
Sbjct: 461 RVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQS 520
Query: 136 -ILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
LK+ Q KE +E +LA LQ+K + ++LQ E
Sbjct: 521 EYLKISQEKEQQE-SLALEELELQKKAILTESENKLRDLQQE 561
Score = 31.6 bits (70), Expect = 0.38
Identities = 21/94 (22%), Positives = 46/94 (48%), Gaps = 15/94 (15%)
Query: 83 EIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQI 142
+IQ +L++ E K ++ +LK+ +++ + L+ +E++ + KME+
Sbjct: 1464 QIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKS-----------KMEKK 1512
Query: 143 KENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
+ N E L + R+ E E H + K +++E
Sbjct: 1513 ESNLETELKSQTARIMELEDHITQ----KTIEIE 1542
Score = 30.8 bits (68), Expect = 0.65
Identities = 33/145 (22%), Positives = 70/145 (48%), Gaps = 15/145 (10%)
Query: 25 FYPEPRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEI 84
F +N T + ++VKQ + +LK + E L KD + +++
Sbjct: 664 FQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVL-----KDQT-DKM 717
Query: 85 QKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKM--EQI 142
+++LEA + +K+ Q + + ++ E + +KAL++ N + +L+LK + +
Sbjct: 718 KQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN-----QLELLLKERDKHL 772
Query: 143 KENRE--ANLAAIIERLQEKERHAA 165
KE++ NL A I+R + + + A+
Sbjct: 773 KEHQAHVENLEADIKRSEGELQQAS 797
Score = 28.9 bits (63), Expect = 2.5
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 11/96 (11%)
Query: 77 KDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHERE--------VLQKALEENNNFS 128
K ++ E QKK E + Q L Q EK+ E E V + LE+ N
Sbjct: 840 KQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQ 899
Query: 129 KMAEEKLILK---MEQIKENREANLAAIIERLQEKE 161
+ ++ L+ K + Q++E ++ + + ++L KE
Sbjct: 900 EQTKQILVEKENMILQMREGQKKEIEILTQKLSAKE 935
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 43.9 bits (102), Expect = 7e-05
Identities = 32/106 (30%), Positives = 54/106 (50%), Gaps = 11/106 (10%)
Query: 75 KKKDLSLEEIQ-KKLEAAEERRKSQEAQVLKQ-------LAEKREHEREVLQKALEENNN 126
++++L EE Q +KLE E RR+ QE + +Q L K+E ER Q+ E
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 127 FSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKE 172
+ EE+ + +Q++ +E + R QE+ER ++RR +E
Sbjct: 327 RREQQEER---REQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Score = 42.7 bits (99), Expect = 2e-04
Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLI--LKM 139
E+ Q++L ++ R+ QE + +Q E+RE + Q+ + EE+ L+
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 140 EQIKENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
EQ +E RE L R QE+ER ++RR ++L+ E
Sbjct: 354 EQEEERREQQL----RREQEEERREQQLRREQQLRRE 386
Score = 38.5 bits (88), Expect = 0.003
Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
Query: 83 EIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQI 142
E Q + E EER + + Q ++ KRE E EE + K LK +Q
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 143 KENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
+E RE L +L+E+ER + RR ++L+ E
Sbjct: 482 EERRERWL-----KLEEEERREQQERREQQLRRE 510
Score = 38.5 bits (88), Expect = 0.003
Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEK 134
+KKD +E ++ L E+R+ QE + +Q E+ E ++E Q EE + E+
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERE--RQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 135 LILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
K E++++ E L E+ + +ER + R +ELQ E
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERE-RQCREEEELQQE 1119
Score = 35.8 bits (81), Expect = 0.020
Identities = 25/103 (24%), Positives = 52/103 (50%), Gaps = 9/103 (8%)
Query: 70 TLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSK 129
T+ +++ L EE Q++ E EE + ++ + + E++E E++ Q+ L +
Sbjct: 251 TVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ--QQRLRREQQLRR 308
Query: 130 MAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKE 172
EE+ + E+ +E +E R Q++ER ++RR +E
Sbjct: 309 KQEEERREQQEERREQQE-------RREQQEERREQQLRREQE 344
Score = 35.8 bits (81), Expect = 0.020
Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 16/117 (13%)
Query: 76 KKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAE----------KREHEREVLQKALEENN 125
K+D E ++ L+ EE R+ Q+ + +QL KR+ E E LQ+ L
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
Query: 126 NFSKMAEEK--LILKMEQIK----ENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
+ EE+ +LK E+ K E RE L E +++ E RR + L+ E
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Score = 35.4 bits (80), Expect = 0.026
Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EE + L+ EE + ++ + +QL +E ER LEE + + L+ EQ
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511
Query: 142 IKENREANLAAIIE--RLQEKERHAAEVRRNKE 172
+E RE L E RLQ++ R ++RR +E
Sbjct: 512 -EERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Score = 33.5 bits (75), Expect = 0.100
Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 13/106 (12%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLK----QLAEKREHEREVLQKALEENNNFSKM 130
+++ L+E + L+ +ERR+SQE + + QL E+R+ R L ++K
Sbjct: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL---------YAKP 893
Query: 131 AEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
A ++ + K +Q+ + E L + ++ + R ++LQ E
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE 939
Score = 33.1 bits (74), Expect = 0.13
Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Query: 89 EAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREA 148
E E+R K +E + L+Q E+R +R ++ EE +EE+ + +Q++ ++
Sbjct: 596 ERLEQRLKREEVERLEQ--EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 149 NLAAIIERLQEKERHAAEVRRNKE 172
++R +E+ER ++R E
Sbjct: 654 RREQRLKREEEEERLEQRLKREHE 677
Score = 33.1 bits (74), Expect = 0.13
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 6/106 (5%)
Query: 74 PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEE 133
P+++ L EE + EA RKSQE + L + + + R+ + E + EE
Sbjct: 1294 PEEEQLEREE---QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
Query: 134 KLILKMEQIKENREANLAAIIER---LQEKERHAAEVRRNKELQVE 176
+ + + E+ ++ RE L + L+E++R + R K L+ E
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
Score = 32.7 bits (73), Expect = 0.17
Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 9/103 (8%)
Query: 83 EIQKKLEAAEERRKSQ------EAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLI 136
E Q + E EERR+ Q E + +QL +++ RE + ++ ++ E+ +
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407
Query: 137 LKMEQIKENREANLAAIIERLQEKERHA---AEVRRNKELQVE 176
+ +Q++ ++ + R QE+ERH + RR + L+ E
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
Score = 32.0 bits (71), Expect = 0.29
Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEK 134
+K+ E + + EE+ + VL++ EK + E Q+ L+E + E +
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 135 LILKMEQIKENREANL--AAIIERLQEKERHAAEVRRNKE 172
+ + Q +E ++ L + R QE+ER + R ++
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Score = 31.6 bits (70), Expect = 0.38
Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 12/113 (10%)
Query: 71 LASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKM 130
L ++++L EE +K+ +ER+ +E Q+ ++ + ERE ++ E + K
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE-KRRRQERERQYRK- 962
Query: 131 AEEKLILKMEQI---------KENREANLAAIIERLQEKERHAAEVRRNKELQ 174
++KL K EQ+ ++ RE E QE+E+ E R + Q
Sbjct: 963 -DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Score = 31.2 bits (69), Expect = 0.50
Identities = 24/109 (22%), Positives = 52/109 (47%), Gaps = 12/109 (11%)
Query: 75 KKKDLSLEEIQKKLEAAE-ERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEE 133
+++ L E +K+LE E+R +E + + KRE ER + E+ + +
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 134 KLILKMEQIKENREANL----------AAIIERLQEKERHAAEVRRNKE 172
+ + ++EQ +E RE L +++ +++ER ++RR ++
Sbjct: 605 EEVERLEQ-EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Score = 31.2 bits (69), Expect = 0.50
Identities = 29/143 (20%), Positives = 68/143 (47%), Gaps = 9/143 (6%)
Query: 43 KQINKRASGQAFELILKPPSPISEA-PRTLASPKKKDLSLEEIQKKL-EAAEERRKSQEA 100
+++ + + E LK P E + L S ++++ ++++++ E E+R K +E
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Query: 101 QVLKQLAEKREHEREVLQKAL--EENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQ 158
+ + KREHE E ++ L EE + + ++ Q++ +A + + R +
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 159 EKE-----RHAAEVRRNKELQVE 176
++E + E RR +E +++
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQ 747
Score = 30.8 bits (68), Expect = 0.65
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Query: 73 SPKKKDLSLEEIQKKLEAAEERRKS-QEAQVLKQLAEKREHEREVLQKALEENNNFSKMA 131
S +++D E ++++ E RK +E Q L+Q ++ E E L + EE +
Sbjct: 1424 SRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER 1483
Query: 132 EEKLILKMEQI-KENREANLAAIIERLQEKERHAAE 166
+ K + + +Q+ ++ R+ R QE ER E
Sbjct: 1484 DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Score = 30.0 bits (66), Expect = 1.1
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EE ++ E E RRK +E ++ ++RE + V Q+ E+ + K K+++
Sbjct: 207 EEQLRRRELLELRRKGRE----EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 142 IKENREANLAAIIERLQEKERHAAEVRRNKELQ 174
+ R+ L E+L++ ER R +E Q
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Score = 30.0 bits (66), Expect = 1.1
Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 9/107 (8%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLK--QLAEKREHEREVLQ-----KALEENNNF 127
+++ L +E +K E+ R+ +E Q L+ Q K E E LQ + L + +
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDR 1843
Query: 128 SKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAE--VRRNKE 172
AEE+ + + +E +E +R QE+ER E +RR ++
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
Score = 29.3 bits (64), Expect = 1.9
Identities = 26/115 (22%), Positives = 55/115 (47%), Gaps = 13/115 (11%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQ---VLKQLAEKREHEREVLQKAL------EENN 125
++++ E + + E E+R K ++ + LK+ E HE+E ++ L E
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 126 NFSKMAEEKLILKME----QIKENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
+ K+ EE+ + E Q++ +E ++R +E+ER +R ++L+ E
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Score = 29.3 bits (64), Expect = 1.9
Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EE Q + E E++ +SQE+ + E+ ERE Q ++ + + EE+L L+ ++
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 142 IKENREANLAAIIERLQEKERHAAEVRRNKELQ 174
+ +E + + + +E+ A + + +E Q
Sbjct: 1835 QRLRQERD-----RQYRAEEQFATQEKSRREEQ 1862
Score = 28.9 bits (63), Expect = 2.5
Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 10/100 (10%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
++++++ + E++ +E Q+ ++ +RE + Q+ E + EE+ K EQ
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 142 IKENREANLAA-------IIERLQEKERHAAEVRRNKELQ 174
E RE L ++R +E ERH E RR ++L+
Sbjct: 441 --ERREQRLKREQEERRDWLKREEETERHEQE-RRKQQLK 477
Score = 28.9 bits (63), Expect = 2.5
Identities = 23/92 (25%), Positives = 47/92 (51%), Gaps = 9/92 (9%)
Query: 84 IQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEE---KLILKME 140
++++ E ++R K ++ + L+Q KRE + Q+ E + EE + +LK E
Sbjct: 579 LKREEERRQQRLKREQEERLEQRL-KREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 141 QIKENREANLAAIIERLQEKERHAAEVRRNKE 172
+ +E R+ L R +++ER ++R +E
Sbjct: 638 EQEERRQQQL-----RREQQERREQRLKREEE 664
Score = 28.9 bits (63), Expect = 2.5
Identities = 21/96 (21%), Positives = 42/96 (43%)
Query: 81 LEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKME 140
LEE Q+ ER+ +E Q L+ +++ ++ +K EE S+ ++ + E
Sbjct: 1377 LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436
Query: 141 QIKENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
Q +E + E Q ++ + R ++L E
Sbjct: 1437 QQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Score = 28.1 bits (61), Expect = 4.2
Identities = 20/89 (22%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
Query: 85 QKKLEAAEERRKS-QEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIK 143
+++L + E RK +E Q L + +R+ +E Q +E + ++ + EQ++
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1564
Query: 144 ENREANLAAIIERLQEKERHAAEVRRNKE 172
+ RE + ER ++ +VRR ++
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Score = 28.1 bits (61), Expect = 4.2
Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 9/117 (7%)
Query: 66 EAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENN 125
E + L +++ L+E Q+ ER+ +E Q+ ++ +++ +E +K LEE
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754
Query: 126 NFSKMAEEKL--------ILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQ 174
+ E++L + EQ+++ RE E K R ++R+ +E Q
Sbjct: 1755 LRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES-DRKFREEEQLRQEREEQ 1810
Score = 27.7 bits (60), Expect = 5.5
Identities = 17/86 (19%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 38 DDMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKS 97
++ +++ ++ Q E + + + L + + +E++++ EE ++
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 98 QEAQVLKQLAEKREHEREVLQKALEE 123
+E Q+L++ EKR ERE + EE
Sbjct: 1180 EE-QLLREEQEKRRQERERQYREEEE 1204
Score = 27.3 bits (59), Expect = 7.2
Identities = 20/82 (24%), Positives = 39/82 (47%), Gaps = 6/82 (7%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EE Q E E++ + QE + E++ +E +K L+E + E+ + EQ
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Query: 142 IKENREANLAAIIERLQEKERH 163
+++ E E+L+ +ER+
Sbjct: 1731 LRQETEQ------EQLRRQERY 1746
Score = 27.3 bits (59), Expect = 7.2
Identities = 26/114 (22%), Positives = 51/114 (44%), Gaps = 11/114 (9%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKRE----------HEREVLQKALEEN 124
+++ L E +++L E RK +E + L+Q E+++ E E L++ EE
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 125 NNFSKMAEEKLILKMEQIK-ENREANLAAIIERLQEKERHAAEVRRNKELQVEL 177
+ + K + EQ++ E +E L +R E A +++ + EL
Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQEL 1864
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 43.9 bits (102), Expect = 7e-05
Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 14/118 (11%)
Query: 65 SEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKR---EHEREVLQKAL 121
SEA + SP K L+ EE++++ + E R+K E + K+L E++ E R +
Sbjct: 235 SEAKKESLSPGKLKLTFEELERQRQ--ENRKKQAEEEARKRLEEEKRAFEEARRQMVNED 292
Query: 122 EENNNFSKMAE----EKLILKMEQIKENREANLAAIIE-----RLQEKERHAAEVRRN 170
EEN + +K+ + KL L E+++ R + E R++E+++ AE RRN
Sbjct: 293 EENQDTAKIFKGYRPGKLKLSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRN 350
Score = 39.3 bits (90), Expect = 0.002
Identities = 28/94 (29%), Positives = 53/94 (56%), Gaps = 6/94 (6%)
Query: 73 SPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHE--REVLQKALEENNNFSKM 130
+P K +++ EE+ K+ + EE+R+++E + K EK+E E R+ + + EEN F
Sbjct: 370 TPGKLEINFEELLKQ-KMEEEKRRTEEERKHKLEMEKQEFEQLRQEMGEEEEENETFGLS 428
Query: 131 AEEKLILKMEQIKENREANLAAIIER---LQEKE 161
E + ++K+++ + NL + E+ L EKE
Sbjct: 429 REYEELIKLKRSGSIQAKNLKSKFEKIGQLSEKE 462
Score = 32.7 bits (73), Expect = 0.17
Identities = 36/135 (26%), Positives = 66/135 (48%), Gaps = 11/135 (8%)
Query: 54 FELILKPPSPISEAPRTLASPKKK--DLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKRE 111
+E ++K S + L S +K LS +EIQKK+E RR++ + ++ ++ AE
Sbjct: 431 YEELIKLKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERARRRAIDLEIKEREAENFH 490
Query: 112 HEREV-LQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIE-----RLQEKERHA- 164
E +V ++ A + F+ K + EQ+ + RE IE R+Q ++R
Sbjct: 491 EEDDVDVRPARKSEAPFTHKVNMK--ARFEQMAKAREEEEQRRIEEQKLLRMQFEQREID 548
Query: 165 AEVRRNKELQVELSG 179
A +++ +E + E G
Sbjct: 549 AALQKKREEEEEEEG 563
Score = 28.5 bits (62), Expect = 3.2
Identities = 21/94 (22%), Positives = 51/94 (54%), Gaps = 14/94 (14%)
Query: 83 EIQKKLEAAEERRKSQEAQ--VLKQLAEKREHEREVLQKA--LEENNN-----FSKMAEE 133
E++K+ + + +R +E + + + + EKR+ +RE+ ++A +E+ NN S+ ++
Sbjct: 108 EMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKRAEQIEDINNTGTESASEEGDD 167
Query: 134 KLILKMEQIKENR-----EANLAAIIERLQEKER 162
L++ + +K + + N + + +EKER
Sbjct: 168 SLLITVVPVKSYKTSGKMKKNFEDLEKEREEKER 201
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 43.1 bits (100), Expect = 1e-04
Identities = 31/114 (27%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 59 KPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQ 118
K S S+ ++ + K+ LS ++I+++ E +R++ +E + ++ E+ + ERE
Sbjct: 592 KERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRL 651
Query: 119 KALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKE 172
+A E +++ E+L L+ ++ + RE ERL E+ER E R KE
Sbjct: 652 EAFHERKEKARLQRERLQLECQRQRLERERMER---ERL-ERERMRVERERRKE 701
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 43.1 bits (100), Expect = 1e-04
Identities = 29/105 (27%), Positives = 59/105 (56%), Gaps = 4/105 (3%)
Query: 65 SEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAE---KREHEREVLQKAL 121
+EA R LA ++++ +E +++ +ERR+ + + +QLAE +RE ER ++ L
Sbjct: 679 AEAKR-LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 737
Query: 122 EENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAE 166
+E ++ +E+L ++E+ K+ E A + +E+E+ A E
Sbjct: 738 QEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
Score = 40.8 bits (94), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 8/150 (5%)
Query: 29 PRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKL 88
P ++T ++ A + +K +P+ P+ K++ LE +++K
Sbjct: 491 PLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQ-RLENLRRKE 549
Query: 89 EAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEK---LILKMEQIKEN 145
EA + RR+ E ++L E + E L+K L+ +M EEK + K QI E
Sbjct: 550 EAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 609
Query: 146 REANLAAIIERL-QEKERHAAEVRRNKELQ 174
E A ERL +EK + A ++ +E++
Sbjct: 610 TE---KAKEERLAEEKAKKKAAAKKMEEVE 636
Score = 39.7 bits (91), Expect = 0.001
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
Query: 79 LSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILK 138
L EE +K+ A ER + + + KQ+ +K E +KA EE K ++ K
Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 631
Query: 139 MEQI----KENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
ME++ K+ EA +++ +E+ RH +++ KE + E
Sbjct: 632 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE 673
Score = 39.7 bits (91), Expect = 0.001
Identities = 36/138 (26%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 43 KQINKRASGQAFELILKPPSPISEAPRT--LASPKKKDLSLEEIQKKLEAAEER-RKSQE 99
++ K+A+ + E + EA R L +++ E +QKK E +ER RK+ E
Sbjct: 621 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 680
Query: 100 AQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQE 159
A K+LAE+RE ER ++ +E + +E+ + + ++ R + +
Sbjct: 681 A---KRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 737
Query: 160 KERHAAEVRRNKELQVEL 177
+ER A + ++LQ EL
Sbjct: 738 QEREKALRLQKEQLQREL 755
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 43.1 bits (100), Expect = 1e-04
Identities = 29/105 (27%), Positives = 59/105 (56%), Gaps = 4/105 (3%)
Query: 65 SEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAE---KREHEREVLQKAL 121
+EA R LA ++++ +E +++ +ERR+ + + +QLAE +RE ER ++ L
Sbjct: 675 AEAKR-LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 733
Query: 122 EENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAE 166
+E ++ +E+L ++E+ K+ E A + +E+E+ A E
Sbjct: 734 QEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 41.2 bits (95), Expect = 5e-04
Identities = 34/106 (32%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 74 PKKKDLS-LEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAE 132
PK+K+ LE +++K EA + RR+ E ++L E + E L+K L+ +M E
Sbjct: 530 PKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE 589
Query: 133 EK---LILKMEQIKENREANLAAIIERL-QEKERHAAEVRRNKELQ 174
EK + K QI E E A ERL +EK + A ++ +E++
Sbjct: 590 EKKKQIEQKFAQIDEKTE---KAKEERLAEEKAKKKAAAKKMEEVE 632
Score = 39.7 bits (91), Expect = 0.001
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
Query: 79 LSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILK 138
L EE +K+ A ER + + + KQ+ +K E +KA EE K ++ K
Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 627
Query: 139 MEQI----KENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
ME++ K+ EA +++ +E+ RH +++ KE + E
Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE 669
Score = 39.7 bits (91), Expect = 0.001
Identities = 36/138 (26%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 43 KQINKRASGQAFELILKPPSPISEAPRT--LASPKKKDLSLEEIQKKLEAAEER-RKSQE 99
++ K+A+ + E + EA R L +++ E +QKK E +ER RK+ E
Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 676
Query: 100 AQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQE 159
A K+LAE+RE ER ++ +E + +E+ + + ++ R + +
Sbjct: 677 A---KRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 733
Query: 160 KERHAAEVRRNKELQVEL 177
+ER A + ++LQ EL
Sbjct: 734 QEREKALRLQKEQLQREL 751
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 42.7 bits (99), Expect = 2e-04
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 19/146 (13%)
Query: 51 GQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEER----RKSQEA------ 100
G+A EL+L+ + R A ++ +E+ +KLE EE R+SQE
Sbjct: 1013 GRAQELLLQSQRAQEHSSRLQAEKSVLEIQGQELHRKLEVLEEEVRAARQSQEETRGQQQ 1072
Query: 101 ------QVLKQLAEKREHERE---VLQKALEENNNFSKMAEEKLILKMEQIKENREANLA 151
+ L QL ++E E E V + L+ N ++A +L + EQ++ R + A
Sbjct: 1073 ALLRDHKALAQLQRRQEAELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRASVEA 1132
Query: 152 AIIERLQEKERHAAEVRRNKELQVEL 177
+ L E+ER + R + L+ EL
Sbjct: 1133 QEVALLAERERLMQDGHRQRGLEEEL 1158
Score = 33.1 bits (74), Expect = 0.13
Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 8/133 (6%)
Query: 49 ASGQAFELILKPPSPISEAPRTLASPKKK-DLSLEEIQKKLEAAEERRKSQEAQVLKQL- 106
A+GQ E + + EA +++ + ++ + EAAEER + E++ + L
Sbjct: 799 AAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAEERMQVLESEGRQHLE 858
Query: 107 -AEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKE-RHA 164
AE+ E+E LQ LE+ + + ++L ++E ++ E E L+EKE +H
Sbjct: 859 EAERERREKEALQAELEK----AVVRGKELGARLEHLQRELEQAALERQEFLREKESQHQ 914
Query: 165 AEVRRNKELQVEL 177
+ L+ EL
Sbjct: 915 RYQGLEQRLEAEL 927
Score = 26.9 bits (58), Expect = 9.4
Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
Query: 73 SPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKR---EHEREVLQKALEENNNFSK 129
S ++ DLS + + E + R +QE + + LAE + RE+L+++LE ++ +
Sbjct: 1213 SNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSLESRDHLHR 1272
Query: 130 MAEEKL 135
E L
Sbjct: 1273 EQREYL 1278
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 42.7 bits (99), Expect = 2e-04
Identities = 39/113 (34%), Positives = 60/113 (53%), Gaps = 16/113 (14%)
Query: 75 KKKDLSLEEIQKKLEAAEER------RKSQEAQVLKQLAEKREHEREVLQKALEENNNFS 128
K++ LE + K +A EER + QE + +Q EK++ E E +KA EE
Sbjct: 425 KEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEE---AK 481
Query: 129 KMAEEKLILKMEQIKENREANLAAIIERLQE----KERHAAEVRRNKELQVEL 177
+ AEE+L+LK +Q +E +E A+IE+ +E K R AE R + Q+ L
Sbjct: 482 RKAEEELLLKEKQEQEKQE---KAMIEKQKEAAETKAREVAEQMRLEREQIML 531
Score = 42.7 bits (99), Expect = 2e-04
Identities = 35/139 (25%), Positives = 69/139 (49%), Gaps = 12/139 (8%)
Query: 38 DDMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEE-RRK 96
D +E +++ ++A + L + E R KK +E ++K +A EE +RK
Sbjct: 429 DRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKK-----QEGEEKRKAGEEAKRK 483
Query: 97 SQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIER 156
++E +LK+ E+ + E+ +++K E ++ E++ L+ EQI E ER
Sbjct: 484 AEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQ------ER 537
Query: 157 LQEKERHAAEVRRNKELQV 175
L+ K+R ++R ++ V
Sbjct: 538 LERKKRIDEIMKRTRKSDV 556
Score = 32.7 bits (73), Expect = 0.17
Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 61 PSPISE--APRTLASPKKKDLSLEEIQKKLEA---AEERRKSQE---AQVLKQLAEKREH 112
P I+E A RT + P + +E K E A+ERR+ +E A +Q+ EK++
Sbjct: 24 PGKIAEPGAVRT-SQPNYRPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKR 82
Query: 113 EREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKE 172
R +K +EE + ++ K ++E R+ L ERL+ R + E + E
Sbjct: 83 ARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLE 142
Query: 173 LQVELS 178
L+ + S
Sbjct: 143 LKKKYS 148
Score = 30.4 bits (67), Expect = 0.85
Identities = 28/116 (24%), Positives = 57/116 (49%), Gaps = 14/116 (12%)
Query: 66 EAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENN 125
EA + LA K++ L++ Q++ E E ++ Q+ ++L K E ER L++ +
Sbjct: 399 EAAKILAE-KRRQARLQKEQEEQERVE--KEEQDRLEREELKRKAEEERLRLEEEARKQE 455
Query: 126 NFSKMAEEKLILKMEQIKENREANLAA---------IIERLQEKERHAAEVRRNKE 172
K EE+ K ++ +E R+A A + E+ +++++ A + + KE
Sbjct: 456 EERKRQEEEK--KKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKE 509
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 42.4 bits (98), Expect = 2e-04
Identities = 31/138 (22%), Positives = 68/138 (49%), Gaps = 20/138 (14%)
Query: 43 KQINKRASGQAFELILKPPSPISEAPRTLA-SPKKKDLSLEEIQKKLEAAEERRKSQEAQ 101
+Q+ K+ S Q E + ++++ + L S +KKD +EE+++ L + + +E
Sbjct: 800 EQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 859
Query: 102 VLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIK---ENREANLAAIIERLQ 158
+ ++ + + E++V E+L++ ME++K E+ +A L++ + L
Sbjct: 860 LAQEESARTNAEKQV----------------EELLMAMEKVKQELESMKAKLSSTQQSLA 903
Query: 159 EKERHAAEVRRNKELQVE 176
EKE H +R + +E
Sbjct: 904 EKETHLTNLRAERRKHLE 921
Score = 34.3 bits (77), Expect = 0.059
Identities = 19/107 (17%), Positives = 56/107 (52%), Gaps = 2/107 (1%)
Query: 71 LASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKM 130
L + +K LE ++ KL + ++ +E + AE+R+H EVL+ +++ + +
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLE--MKQEALLAAI 935
Query: 131 AEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVEL 177
+E+ + + ++ +++ + +EK+R ++++ + +++L
Sbjct: 936 SEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 982
Score = 26.9 bits (58), Expect = 9.4
Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 15/109 (13%)
Query: 77 KDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLI 136
K+ + +QKK+E +E+ + +E KQ++ +E + LQ + EE L
Sbjct: 569 KERKVNVLQKKIENLQEQLRDKE----KQMSSLKERVKS-LQADTTNTDTALTTLEEALA 623
Query: 137 LK---MEQIKENREANLAAIIERLQEKERHAAEVRRNKE----LQVELS 178
K +E++KE R+ + E+ +E + + +++ KE LQ +LS
Sbjct: 624 EKERTIERLKEQRDRDER---EKQEEIDNYKKDLKDLKEKVSLLQGDLS 669
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 42.4 bits (98), Expect = 2e-04
Identities = 31/138 (22%), Positives = 68/138 (49%), Gaps = 20/138 (14%)
Query: 43 KQINKRASGQAFELILKPPSPISEAPRTLA-SPKKKDLSLEEIQKKLEAAEERRKSQEAQ 101
+Q+ K+ S Q E + ++++ + L S +KKD +EE+++ L + + +E
Sbjct: 772 EQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 831
Query: 102 VLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIK---ENREANLAAIIERLQ 158
+ ++ + + E++V E+L++ ME++K E+ +A L++ + L
Sbjct: 832 LAQEESARTNAEKQV----------------EELLMAMEKVKQELESMKAKLSSTQQSLA 875
Query: 159 EKERHAAEVRRNKELQVE 176
EKE H +R + +E
Sbjct: 876 EKETHLTNLRAERRKHLE 893
Score = 34.3 bits (77), Expect = 0.059
Identities = 19/107 (17%), Positives = 56/107 (52%), Gaps = 2/107 (1%)
Query: 71 LASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKM 130
L + +K LE ++ KL + ++ +E + AE+R+H EVL+ +++ + +
Sbjct: 850 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLE--MKQEALLAAI 907
Query: 131 AEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVEL 177
+E+ + + ++ +++ + +EK+R ++++ + +++L
Sbjct: 908 SEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 954
Score = 26.9 bits (58), Expect = 9.4
Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 15/109 (13%)
Query: 77 KDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLI 136
K+ + +QKK+E +E+ + +E KQ++ +E + LQ + EE L
Sbjct: 541 KERKVNVLQKKIENLQEQLRDKE----KQMSSLKERVKS-LQADTTNTDTALTTLEEALA 595
Query: 137 LK---MEQIKENREANLAAIIERLQEKERHAAEVRRNKE----LQVELS 178
K +E++KE R+ + E+ +E + + +++ KE LQ +LS
Sbjct: 596 EKERTIERLKEQRDRDER---EKQEEIDNYKKDLKDLKEKVSLLQGDLS 641
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 42.4 bits (98), Expect = 2e-04
Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 76 KKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVL-QKALEENNNFSKMAEEK 134
+++ L E + K+ EE+ + QE ++ +Q E RE E+E+ QK L E + EEK
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK 318
Query: 135 LILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
+ + E+++E +E + ERL E+E+ E + Q E
Sbjct: 319 MWEQEEKMRE-QEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Score = 36.6 bits (83), Expect = 0.012
Identities = 23/123 (18%), Positives = 61/123 (49%), Gaps = 1/123 (0%)
Query: 40 MEVKQINKRASGQAFELILKPPSPISEAP-RTLASPKKKDLSLEEIQKKLEAAEERRKSQ 98
+ VK++ ++ F L + + E R ++++ + + ++K+ EER + Q
Sbjct: 208 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 267
Query: 99 EAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQ 158
E ++ +Q + R E+ + ++ E ++ E+K + + E+ + +E + E+++
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327
Query: 159 EKE 161
E+E
Sbjct: 328 EQE 330
Score = 36.6 bits (83), Expect = 0.012
Identities = 29/103 (28%), Positives = 54/103 (52%), Gaps = 7/103 (6%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEK 134
++++ L E QKKL EE+ + QE ++ +Q + RE E ++ ++ EE +EK
Sbjct: 293 REQEKELRE-QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ--EER----LWEQEK 345
Query: 135 LILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVEL 177
+ + EQ ++E + ERL+EKE E + E + ++
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388
Score = 34.3 bits (77), Expect = 0.059
Identities = 18/98 (18%), Positives = 53/98 (54%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEK 134
++++ ++E ++K+ EE+ + QE ++ +Q E E+++ ++ + + +M E+
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365
Query: 135 LILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKE 172
L+ ++ + + + E++QE+ER ++ +E
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Score = 33.1 bits (74), Expect = 0.13
Identities = 24/109 (22%), Positives = 53/109 (48%), Gaps = 7/109 (6%)
Query: 75 KKKDLSLEEI----QKKLEAAEERRKSQEAQVLKQLAEKREHER---EVLQKALEENNNF 127
+KK EE+ ++K++ EE+ + QE ++ +Q + +E E E +K E+
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 128 SKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVE 176
+E+++ + E+ + +E + E+++E+E E + Q E
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
Score = 32.7 bits (73), Expect = 0.17
Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEK 134
+KK EE ++ + +E+ K Q K E+R ERE K + E + EEK
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE---KKMREEEEMMREQEEK 582
Query: 135 LILKMEQIKENREANLAAIIERLQEKE 161
+ + E+++E +E + E++QE+E
Sbjct: 583 MQEQEEKMRE-QEEKMWEQEEKMQEQE 608
Score = 30.4 bits (67), Expect = 0.85
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 83 EIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQI 142
E ++L EER + Q+ + Q EK E++ ++ + + KM EE+ + + E+
Sbjct: 511 EQDERLREKEERMREQKK--MWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Query: 143 KENREANLAAIIERLQEKERHAAE 166
E + E++QE+E E
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMRE 592
Score = 29.3 bits (64), Expect = 1.9
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 74 PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEE 133
P++K+ E Q+K++ EE+ QE ++ Q + ++ Q+ + E + EE
Sbjct: 436 PEQKEKLWE--QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 493
Query: 134 KLILKMEQIKENREANLAAIIERLQEKERHAAEVRR 169
K+ EQ ++E + ERL+EKE E ++
Sbjct: 494 KM-RDQEQKMWDQEERMWEQDERLREKEERMREQKK 528
Score = 28.9 bits (63), Expect = 2.5
Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEK 134
KKK+ E+Q+KL AE + + V K+L K E + +L + +E+
Sbjct: 186 KKKNA---ELQEKLRLAESEKSEIQLNV-KELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 135 LILKMEQIKENREANLAAIIERLQEKE---RHAAEVRRNKE 172
+ + E+ +E + ERL+E+E R E R +E
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE 282
Score = 27.7 bits (60), Expect = 5.5
Identities = 20/82 (24%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEK-REHEREVLQKALEENNNFSKMAEEKLILKME 140
E +++K E E+ K E + Q E+ RE E+++ ++ KM +++ + +
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 141 QIKENREANLAAIIERLQEKER 162
+ KE ++ L E+L E+E+
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEK 447
Score = 27.3 bits (59), Expect = 7.2
Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 10/99 (10%)
Query: 75 KKKD-LSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEE 133
K++D LSLE + + E ++K+ E Q +LAE + E ++ K L+ K+
Sbjct: 166 KERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKR-----KLERA 220
Query: 134 KLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKE 172
K +L Q +E + E L+E+E+ ++R+ +E
Sbjct: 221 KFLLPQVQTNTLQE-EMWRQEEELREQEK---KIRKQEE 255
Score = 27.3 bits (59), Expect = 7.2
Identities = 19/74 (25%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 76 KKDLSLEEIQKKLEAAEERRKSQE--AQVLKQLAEKREHEREVLQKALEENNNFSKMAEE 133
+++ +E +KK EE+ + +E + K++ E+ E RE +K ++E + EE
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK-MQEQEEKMREQEE 595
Query: 134 KLILKMEQIKENRE 147
K+ + E+++E E
Sbjct: 596 KMWEQEEKMQEQEE 609
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 42.0 bits (97), Expect = 3e-04
Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 8/98 (8%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHERE------VLQKALEENNNFSKMAEEKL 135
+EI + + EE R+ QE + L++L E+R E E +L+K EE +++ EE+
Sbjct: 794 QEIALRRQREEEERQQQE-EALRRLEERRREEEERRKQEELLRKQEEEAAKWAR-EEEEA 851
Query: 136 ILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKEL 173
++E+ + E A + +E++R EV+R KEL
Sbjct: 852 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKEL 889
Score = 35.8 bits (81), Expect = 0.020
Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 29/138 (21%)
Query: 66 EAPRTLASPKKKDLSLEEIQKKL--EAAEERRKSQEAQVLKQLAEKREHEREVLQKALEE 123
EA R L ++ L +EE +L E E +RK E Q K+L +R+ ++E L++ L++
Sbjct: 850 EAQRRL---EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR-LQQ 905
Query: 124 NNNFSKMAEEKL----------------------ILKMEQIKENREANLAAIIERLQEKE 161
++A+ KL + ++++++E RE L +R Q++E
Sbjct: 906 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE-EQRRQQRE 964
Query: 162 RHAAEVRRNKELQVELSG 179
A ++ ++ Q +LSG
Sbjct: 965 LMKALQQQQQQQQQKLSG 982
Score = 33.1 bits (74), Expect = 0.13
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 52 QAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKRE 111
Q ++ L S + T A + LSL EIQK E E + + ++ + ++L + +
Sbjct: 911 QLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQ 970
Query: 112 HEREVLQKALEENNNFSK-MAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRN 170
+++ Q+ L N SK K +L+++Q EA ++ Q++ + R N
Sbjct: 971 QQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ----EEARQMQKQQQQQQQHQQPNRARNN 1026
Query: 171 KELQVELS 178
+ S
Sbjct: 1027 THSNLHTS 1034
Score = 32.3 bits (72), Expect = 0.22
Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 18/92 (19%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EEI ++ + E +R+ +E +LA +++ E + E+++ L+ ++
Sbjct: 760 EEILRRQQEEERKRREEE-----ELARRKQEEA------------LRRQREQEIALRRQR 802
Query: 142 IKENREANLAAIIERLQEKERHAAEVRRNKEL 173
+E R+ A + RL+E+ R E R+ +EL
Sbjct: 803 EEEERQQQEEA-LRRLEERRREEEERRKQEEL 833
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 42.0 bits (97), Expect = 3e-04
Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 8/98 (8%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHERE------VLQKALEENNNFSKMAEEKL 135
+EI + + EE R+ QE + L++L E+R E E +L+K EE +++ EE+
Sbjct: 821 QEIALRRQREEEERQQQE-EALRRLEERRREEEERRKQEELLRKQEEEAAKWAR-EEEEA 878
Query: 136 ILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKEL 173
++E+ + E A + +E++R EV+R KEL
Sbjct: 879 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKEL 916
Score = 35.8 bits (81), Expect = 0.020
Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 29/138 (21%)
Query: 66 EAPRTLASPKKKDLSLEEIQKKL--EAAEERRKSQEAQVLKQLAEKREHEREVLQKALEE 123
EA R L ++ L +EE +L E E +RK E Q K+L +R+ ++E L++ L++
Sbjct: 877 EAQRRL---EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR-LQQ 932
Query: 124 NNNFSKMAEEKL----------------------ILKMEQIKENREANLAAIIERLQEKE 161
++A+ KL + ++++++E RE L +R Q++E
Sbjct: 933 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE-EQRRQQRE 991
Query: 162 RHAAEVRRNKELQVELSG 179
A ++ ++ Q +LSG
Sbjct: 992 LMKALQQQQQQQQQKLSG 1009
Score = 33.1 bits (74), Expect = 0.13
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 52 QAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKRE 111
Q ++ L S + T A + LSL EIQK E E + + ++ + ++L + +
Sbjct: 938 QLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQ 997
Query: 112 HEREVLQKALEENNNFSK-MAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRN 170
+++ Q+ L N SK K +L+++Q EA ++ Q++ + R N
Sbjct: 998 QQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ----EEARQMQKQQQQQQQHQQPNRARNN 1053
Query: 171 KELQVELS 178
+ S
Sbjct: 1054 THSNLHTS 1061
Score = 32.3 bits (72), Expect = 0.22
Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 18/92 (19%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EEI ++ + E +R+ +E +LA +++ E + E+++ L+ ++
Sbjct: 787 EEILRRQQEEERKRREEE-----ELARRKQEEA------------LRRQREQEIALRRQR 829
Query: 142 IKENREANLAAIIERLQEKERHAAEVRRNKEL 173
+E R+ A + RL+E+ R E R+ +EL
Sbjct: 830 EEEERQQQEEA-LRRLEERRREEEERRKQEEL 860
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 42.0 bits (97), Expect = 3e-04
Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 8/98 (8%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHERE------VLQKALEENNNFSKMAEEKL 135
+EI + + EE R+ QE + L++L E+R E E +L+K EE +++ EE+
Sbjct: 800 QEIALRRQREEEERQQQE-EALRRLEERRREEEERRKQEELLRKQEEEAAKWAR-EEEEA 857
Query: 136 ILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKEL 173
++E+ + E A + +E++R EV+R KEL
Sbjct: 858 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKEL 895
Score = 35.8 bits (81), Expect = 0.020
Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 29/138 (21%)
Query: 66 EAPRTLASPKKKDLSLEEIQKKL--EAAEERRKSQEAQVLKQLAEKREHEREVLQKALEE 123
EA R L ++ L +EE +L E E +RK E Q K+L +R+ ++E L++ L++
Sbjct: 856 EAQRRL---EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR-LQQ 911
Query: 124 NNNFSKMAEEKL----------------------ILKMEQIKENREANLAAIIERLQEKE 161
++A+ KL + ++++++E RE L +R Q++E
Sbjct: 912 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE-EQRRQQRE 970
Query: 162 RHAAEVRRNKELQVELSG 179
A ++ ++ Q +LSG
Sbjct: 971 LMKALQQQQQQQQQKLSG 988
Score = 33.1 bits (74), Expect = 0.13
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 52 QAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKRE 111
Q ++ L S + T A + LSL EIQK E E + + ++ + ++L + +
Sbjct: 917 QLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQ 976
Query: 112 HEREVLQKALEENNNFSK-MAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRN 170
+++ Q+ L N SK K +L+++Q EA ++ Q++ + R N
Sbjct: 977 QQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ----EEARQMQKQQQQQQQHQQPNRARNN 1032
Query: 171 KELQVELS 178
+ S
Sbjct: 1033 THSNLHTS 1040
Score = 32.3 bits (72), Expect = 0.22
Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 18/92 (19%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EEI ++ + E +R+ +E +LA +++ E + E+++ L+ ++
Sbjct: 766 EEILRRQQEEERKRREEE-----ELARRKQEEA------------LRRQREQEIALRRQR 808
Query: 142 IKENREANLAAIIERLQEKERHAAEVRRNKEL 173
+E R+ A + RL+E+ R E R+ +EL
Sbjct: 809 EEEERQQQEEA-LRRLEERRREEEERRKQEEL 839
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 42.0 bits (97), Expect = 3e-04
Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 8/98 (8%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHERE------VLQKALEENNNFSKMAEEKL 135
+EI + + EE R+ QE + L++L E+R E E +L+K EE +++ EE+
Sbjct: 800 QEIALRRQREEEERQQQE-EALRRLEERRREEEERRKQEELLRKQEEEAAKWAR-EEEEA 857
Query: 136 ILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKEL 173
++E+ + E A + +E++R EV+R KEL
Sbjct: 858 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKEL 895
Score = 35.8 bits (81), Expect = 0.020
Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 29/138 (21%)
Query: 66 EAPRTLASPKKKDLSLEEIQKKL--EAAEERRKSQEAQVLKQLAEKREHEREVLQKALEE 123
EA R L ++ L +EE +L E E +RK E Q K+L +R+ ++E L++ L++
Sbjct: 856 EAQRRL---EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRR-LQQ 911
Query: 124 NNNFSKMAEEKL----------------------ILKMEQIKENREANLAAIIERLQEKE 161
++A+ KL + ++++++E RE L +R Q++E
Sbjct: 912 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE-EQRRQQRE 970
Query: 162 RHAAEVRRNKELQVELSG 179
A ++ ++ Q +LSG
Sbjct: 971 LMKALQQQQQQQQQKLSG 988
Score = 33.1 bits (74), Expect = 0.13
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 5/128 (3%)
Query: 52 QAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKRE 111
Q ++ L S + T A + LSL EIQK E E + + ++ + ++L + +
Sbjct: 917 QLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQ 976
Query: 112 HEREVLQKALEENNNFSK-MAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRN 170
+++ Q+ L N SK K +L+++Q EA ++ Q++ + R N
Sbjct: 977 QQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ----EEARQMQKQQQQQQQHQQPNRARNN 1032
Query: 171 KELQVELS 178
+ S
Sbjct: 1033 THSNLHTS 1040
Score = 32.3 bits (72), Expect = 0.22
Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 18/92 (19%)
Query: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141
EEI ++ + E +R+ +E +LA +++ E + E+++ L+ ++
Sbjct: 766 EEILRRQQEEERKRREEE-----ELARRKQEEA------------LRRQREQEIALRRQR 808
Query: 142 IKENREANLAAIIERLQEKERHAAEVRRNKEL 173
+E R+ A + RL+E+ R E R+ +EL
Sbjct: 809 EEEERQQQEEA-LRRLEERRREEEERRKQEEL 839
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 42.0 bits (97), Expect = 3e-04
Identities = 33/153 (21%), Positives = 72/153 (47%), Gaps = 18/153 (11%)
Query: 39 DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQ 98
+++ Q +++ ++ P + + +A+ KK LE+++++L+ E++ K +
Sbjct: 632 ELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKE 691
Query: 99 EAQVLKQLAEKR----EHEREVLQKAL-----EENNNFSKM---------AEEKLILKME 140
++ + A ++ E + E LQK L EE S+M +E+ I M+
Sbjct: 692 NKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQ 751
Query: 141 QIKENREANLAAIIERLQEKERHAAEVRRNKEL 173
Q++E +AN + ER++ + H +EL
Sbjct: 752 QLREKDDANFKLMSERIKSNQIHKLLKEEKEEL 784
Score = 30.4 bits (67), Expect = 0.85
Identities = 25/120 (20%), Positives = 62/120 (51%), Gaps = 6/120 (5%)
Query: 58 LKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVL 117
LKP S + + + ++D + + ++ E E R+ +E + ++ +++E ERE
Sbjct: 536 LKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKERERE-- 593
Query: 118 QKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVEL 177
++ L+E+ A++K K + ++ A II++L+ + + A E ++ +L +++
Sbjct: 594 KQKLKESEKERDSAKDKEKGKHDDGRKKE----AEIIKQLKIELKKAQESQKEMKLLLDM 649
Score = 30.0 bits (66), Expect = 1.1
Identities = 23/121 (19%), Positives = 56/121 (46%), Gaps = 1/121 (0%)
Query: 58 LKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVL 117
L+ S + ++ + PK + L+ + L + K+ + + +++ E ERE
Sbjct: 513 LRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERE 572
Query: 118 QKALEENNNFSKMAEEKLILKMEQIKEN-REANLAAIIERLQEKERHAAEVRRNKELQVE 176
++ E + E++ + +++KE+ +E + A E+ + + E K+L++E
Sbjct: 573 RREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIE 632
Query: 177 L 177
L
Sbjct: 633 L 633
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 41.6 bits (96), Expect = 4e-04
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 6/130 (4%)
Query: 38 DDMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKS 97
D +EV+Q+ +A + + ++ +E + + K+K E+I+++ E ER K
Sbjct: 298 DTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEK----EKIEREKEELMERLKQ 353
Query: 98 QEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERL 157
E Q K E E R L+ LE+ ++ EKL + ++ +E +EA L A ++
Sbjct: 354 IEEQTKKAQQELEEQTRRALE--LEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQK 411
Query: 158 QEKERHAAEV 167
+ +E+ A E+
Sbjct: 412 KTQEQLALEM 421
Score = 35.8 bits (81), Expect = 0.020
Identities = 39/157 (24%), Positives = 72/157 (45%), Gaps = 15/157 (9%)
Query: 32 INIYTYDDMEVKQIN------KRASGQAFELILKP-----PSPISEAPRTLASPKKKDLS 80
+NIY +D +I + S + ++KP P + APR + K+ L+
Sbjct: 225 LNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRIN--KRILA 282
Query: 81 LEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKME 140
L +L + + E Q +K A + +H+++ +++A+ EN + EK K+E
Sbjct: 283 LCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-MERAMLENEKKKREMAEKEKEKIE 341
Query: 141 QIKENREANLAAIIERLQEKERHAAE-VRRNKELQVE 176
+ KE L I E+ ++ ++ E RR EL+ E
Sbjct: 342 REKEELMERLKQIEEQTKKAQQELEEQTRRALELEQE 378
Score = 33.9 bits (76), Expect = 0.077
Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 13/152 (8%)
Query: 26 YPEPRNINIYTYDDMEVKQINKRASGQAFEL----ILKPPSPISEAPRTLASPKKKDLSL 81
+ E RNI+ + +K I+K+A F I K + L ++K ++
Sbjct: 242 WSEIRNIS-FNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300
Query: 82 EEIQKKLEAAEERRKSQEAQVL----KQLAEKREHEREVLQKALEENNNFSKMAEEKLIL 137
E Q K +A EE+ + Q + + K+ E E E+E +++ EE K EE+
Sbjct: 301 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKK 360
Query: 138 KMEQIKENREANLAAIIERLQEKERHAAEVRR 169
++++E L E QE++R +E +
Sbjct: 361 AQQELEEQTRRAL----ELEQERKRAQSEAEK 388
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 41.6 bits (96), Expect = 4e-04
Identities = 38/149 (25%), Positives = 73/149 (48%), Gaps = 16/149 (10%)
Query: 39 DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLS-----LEEIQKKLEAAEE 93
++E+ RA + + L S ++E+ + K DL+ LEE + L+ +
Sbjct: 719 ELELSMTKLRAEEASLQDSLSKLSALNES----LAQDKLDLNRLVAQLEEEKSALQG-RQ 773
Query: 94 RRKSQEAQVLKQLAEKREH---EREVLQKALEENNNFSKMAEEKLILKMEQIKENR---E 147
R+ QEA V ++ E+ E E+EV ++ LE + ++ A+E L ++ ++ R +
Sbjct: 774 RQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQ 833
Query: 148 ANLAAIIERLQEKERHAAEVRRNKELQVE 176
LA + +L +E+ + RR + QVE
Sbjct: 834 EQLAQLSRQLSGREQELEQARREAQRQVE 862
Score = 38.5 bits (88), Expect = 0.003
Identities = 39/111 (35%), Positives = 56/111 (50%), Gaps = 21/111 (18%)
Query: 81 LEEIQKKLEAAEERRK--SQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAE-EKLIL 137
L E Q+KL ++E R+ QEA L++ + ERE L+++ EE + K AE E++ L
Sbjct: 1177 LLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISL 1236
Query: 138 KMEQIKENREANLAAIIER--------------LQEKERHAAEVRRNKELQ 174
K+ E++E LA + E LQE ER E RR ELQ
Sbjct: 1237 KL--ANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARR--ELQ 1283
Score = 31.6 bits (70), Expect = 0.38
Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 19/149 (12%)
Query: 41 EVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEA 100
EVK +R Q + + + EA L++ L + + EAA E++ +A
Sbjct: 312 EVKMFTERDLLQLGGELARTSRAVQEAGLGLST------GLRLAESRAEAALEKQALLQA 365
Query: 101 QVLKQLAEKREHEREVLQKALEENNNFSKMAE------------EKLILKMEQIKENREA 148
Q+ +QL +K E+++ Q+ ++ + + + ++ EK L+ +Q+ ++
Sbjct: 366 QLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTE 425
Query: 149 NLAAIIERLQEKERHAAEVRRNKELQVEL 177
L A +E L+ +E+ A E + LQ L
Sbjct: 426 KLEA-LESLRLQEQAALETEDGEGLQQTL 453
Score = 31.2 bits (69), Expect = 0.50
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 4/135 (2%)
Query: 41 EVKQINKRASGQAFELIL---KPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKS 97
E + + K +G A +L+ + + EA R + + SL E+Q++L E RR+
Sbjct: 870 EKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 929
Query: 98 QEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERL 157
EA+ L K E+ + K + +K ++ + ++ REA A++ E+
Sbjct: 930 LEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQ-ASLREQR 988
Query: 158 QEKERHAAEVRRNKE 172
E ++R KE
Sbjct: 989 AAHEEDLQRLQREKE 1003
Score = 30.8 bits (68), Expect = 0.65
Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
Query: 65 SEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEEN 124
S +L +++ L + ++KL+AA+E + Q + L++ E + +++ LE +
Sbjct: 606 SNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDR-LEEEQEDAVQDGARVRRELERS 664
Query: 125 NNFSKMAEEKLILKMEQIKENREANLAAIIER--LQEKERHAAEVRRNKE---LQVELS 178
+ + E K + +++ E REA A ++R LQ ++ AE E +++ELS
Sbjct: 665 HRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELS 723
Score = 30.0 bits (66), Expect = 1.1
Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 11/106 (10%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEK 134
++KDL+ +++Q L+ A+ + E + + EK+ E++ + K L E A E
Sbjct: 377 REKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLE----ALES 432
Query: 135 LILKMEQIKENREANLAAIIERLQEKERHAAE-VRRNKELQVELSG 179
L L+ + E + E LQ+ R A+ V + E V+LSG
Sbjct: 433 LRLQEQAALETEDG------EGLQQTLRDLAQAVLSDSESGVQLSG 472
Score = 28.9 bits (63), Expect = 2.5
Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 13/137 (9%)
Query: 40 MEVKQINKRASGQAFELILKPPSPISEAP----RTLASPKKKDLSLEEIQKKLEAAEERR 95
+E ++ A GQA L+L + E + +A+ +K L E + +KL AE
Sbjct: 923 LEARREQLEAEGQA--LLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAE--- 977
Query: 96 KSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIE 155
+EAQ L E+R E LQ+ E + E + Q++ +E LA +
Sbjct: 978 --REAQA--SLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEA 1033
Query: 156 RLQEKERHAAEVRRNKE 172
+E A +++ ++
Sbjct: 1034 EKEELSEEIAALQQERD 1050
Score = 27.7 bits (60), Expect = 5.5
Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 5/57 (8%)
Query: 83 EIQKKLEAAE--ERRKSQEA---QVLKQLAEKREHEREVLQKALEENNNFSKMAEEK 134
E+Q+ A E R KS A QV +Q AE+ ERE LQ A EE EE+
Sbjct: 590 EVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEE 646
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 41.2 bits (95), Expect = 5e-04
Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 10/102 (9%)
Query: 71 LASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKM 130
+AS KK ++ L++++ ++EAA + R Q+ K A+ ++++RE+ + + F++
Sbjct: 1616 VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQS 1675
Query: 131 AEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKE 172
E + LK +L A I +LQE+ + RR+ E
Sbjct: 1676 KESEKKLK----------SLEAEILQLQEELASSERARRHAE 1707
Score = 40.8 bits (94), Expect = 6e-04
Identities = 30/107 (28%), Positives = 55/107 (51%), Gaps = 10/107 (9%)
Query: 66 EAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENN 125
+A R A +K+DLS EE++ E+ + AQ ++L KRE E L+KALEE
Sbjct: 1131 KASRNKAEKQKRDLS-EELEALKTELEDTLDTTAAQ--QELRTKREQEVAELKKALEEET 1187
Query: 126 NFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKE 172
+ +++ +++ L + E+L++ +R A + +NK+
Sbjct: 1188 KNHE-------AQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQ 1227
Score = 39.3 bits (90), Expect = 0.002
Identities = 32/131 (24%), Positives = 67/131 (51%), Gaps = 20/131 (15%)
Query: 65 SEAPRTLASPKKKDLS--LEEIQKKLEAAEER-------RKSQEAQV--LKQLAEKREHE 113
+E R + KK++L L +++ ++E EER +K +A + L++ ++ E
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 114 REVLQ-KALEENNNFSKMAEEKLIL--------KMEQIKENREANLAAIIERLQEKERHA 164
R+ LQ + + KM EE L+L K +++ E+R A ++ + +EK ++
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 165 AEVRRNKELQV 175
A++R +E+ +
Sbjct: 1026 AKIRNKQEVMI 1036
Score = 32.3 bits (72), Expect = 0.22
Identities = 25/114 (21%), Positives = 59/114 (51%), Gaps = 19/114 (16%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNN-------- 126
KK +++++++L+ E R+ + + + A+ ++ E E+L LE+ N+
Sbjct: 946 KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEIL--LLEDQNSKFIKEKKL 1003
Query: 127 --------FSKMAEEKLILK-MEQIKENREANLAAIIERLQEKERHAAEVRRNK 171
S++AEE+ K + +I+ +E ++ + ERL+++E+ E+ + K
Sbjct: 1004 MEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAK 1057
Score = 32.0 bits (71), Expect = 0.29
Identities = 30/132 (22%), Positives = 62/132 (46%), Gaps = 15/132 (11%)
Query: 58 LKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQ---LAEKREHER 114
+KP ++ L + ++ L ++E Q K+E E + + Q+L++ LAE+ + E
Sbjct: 841 VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET 900
Query: 115 EVLQKALEENNNFS--KMAEEKLILKME----------QIKENREANLAAIIERLQEKER 162
E+ +A E + K E+++ +E QI +N + + A I+ L+E+
Sbjct: 901 ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960
Query: 163 HAAEVRRNKELQ 174
R+ +L+
Sbjct: 961 EEEGARQKLQLE 972
Score = 32.0 bits (71), Expect = 0.29
Identities = 29/113 (25%), Positives = 58/113 (51%), Gaps = 13/113 (11%)
Query: 75 KKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMA--- 131
KK D ++E+ K+ + R + + A+ +L + ++ +L++A ++ F+K A
Sbjct: 1255 KKLDAQVQELHAKVSEGD-RLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASL 1313
Query: 132 EEKLILKMEQIKEN--REANLAAIIERL-------QEKERHAAEVRRNKELQV 175
E +L E ++E ++ NL++ I +L QE++ E R+N E QV
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Score = 31.2 bits (69), Expect = 0.50
Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 15/104 (14%)
Query: 84 IQKKLEAAEERRKSQEAQVL---KQLAEKR----------EHEREVLQKALEENNNFSKM 130
+Q++ E EE RK+ E QVL QLA+ + E E +K L++ S+
Sbjct: 1348 LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407
Query: 131 AEEKLIL--KMEQIKENREANLAAIIERLQEKERHAAEVRRNKE 172
EEK + K+E+ K + L + L + + A+ + + ++
Sbjct: 1408 LEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQK 1451
Score = 30.8 bits (68), Expect = 0.65
Identities = 43/144 (29%), Positives = 64/144 (44%), Gaps = 40/144 (27%)
Query: 71 LASPKKK---DL----SLEEIQKKL----EAAEER-------------RKSQEAQVLKQL 106
LA KKK DL SLEE +KKL EA +R K++ Q L L
Sbjct: 1373 LADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDL 1432
Query: 107 AEKREHEREVLQKALEENNNFSK-MAEEKLILKM-----------EQIKENREANLA-AI 153
+H+R+V ++ F + +AEEK I + KE + +LA A+
Sbjct: 1433 TVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARAL 1492
Query: 154 IERLQEKERHAAEVRRNKELQVEL 177
E L+ KE R+NK+L+ ++
Sbjct: 1493 EEALEAKEEFE---RQNKQLRADM 1513
Score = 29.3 bits (64), Expect = 1.9
Identities = 36/133 (27%), Positives = 58/133 (43%), Gaps = 20/133 (15%)
Query: 64 ISEAPRTLASPKKKDLSLEEIQKKLEA-----------AEERRKSQEAQVLKQLAEKREH 112
+ +A R A+ +K LE K+L +E +RK +AQV + A+ E
Sbjct: 1212 LEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEG 1271
Query: 113 ER------EVLQKALEENNNFSKMAE--EKLILKMEQIKENREANLAAIIERLQEKERHA 164
+R E K E +N S + E EK +K + + E+ L E LQE+ R
Sbjct: 1272 DRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQK 1331
Query: 165 AEV-RRNKELQVE 176
+ R ++L+ E
Sbjct: 1332 LNLSSRIRQLEEE 1344
Score = 29.3 bits (64), Expect = 1.9
Identities = 25/98 (25%), Positives = 52/98 (53%), Gaps = 11/98 (11%)
Query: 80 SLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKM 139
S +++ K + E+ +++ E QV + + E E E+ +A E+ A+ +L + M
Sbjct: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDEL--QATED-------AKLRLEVNM 1569
Query: 140 EQIKENREANLAAIIERLQEKERHAAEVRRNKELQVEL 177
+ +K E +L E+ +EK+R +++ +EL+ EL
Sbjct: 1570 QAMKAQFERDLQTRDEQNEEKKR--LLIKQVRELEAEL 1605
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 41.2 bits (95), Expect = 5e-04
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 81 LEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKM----AEEKLI 136
L E QK++E +E+R+ E Q ++ +R+ ERE ++ EE ++ EE+
Sbjct: 392 LAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEER 451
Query: 137 LKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQ 174
+ E+ K E I +L+E++RH EV + + LQ
Sbjct: 452 RRAEEEKRRVEREQEYIRRQLEEEQRH-LEVLQQQLLQ 488
Score = 29.6 bits (65), Expect = 1.4
Identities = 15/52 (28%), Positives = 31/52 (59%), Gaps = 9/52 (17%)
Query: 81 LEEIQKKLEAAEERRKSQEAQ---------VLKQLAEKREHEREVLQKALEE 123
LEE++++ + EERR+++E + + +QL E++ H + Q+ L+E
Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQE 489
Score = 28.1 bits (61), Expect = 4.2
Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 16/107 (14%)
Query: 85 QKKLEAAEERRKSQEAQVLKQLAEKREHEREVL-------------QKALEENNNFSKMA 131
Q+ E +E R+ Q Q +QL E+ E++R++L ++ LEE + A
Sbjct: 361 QENKERSEALRRQQLLQE-QQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA 419
Query: 132 EEKLILKMEQIKENREANLAAIIERLQEKE--RHAAEVRRNKELQVE 176
+ + + ++ + L + R +E+E R A E +R E + E
Sbjct: 420 RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQE 466
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 41.2 bits (95), Expect = 5e-04
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 81 LEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKM----AEEKLI 136
L E QK++E +E+R+ E Q ++ +R+ ERE ++ EE ++ EE+
Sbjct: 392 LAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEER 451
Query: 137 LKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQ 174
+ E+ K E I +L+E++RH EV + + LQ
Sbjct: 452 RRAEEEKRRVEREQEYIRRQLEEEQRH-LEVLQQQLLQ 488
Score = 29.6 bits (65), Expect = 1.4
Identities = 15/52 (28%), Positives = 31/52 (59%), Gaps = 9/52 (17%)
Query: 81 LEEIQKKLEAAEERRKSQEAQ---------VLKQLAEKREHEREVLQKALEE 123
LEE++++ + EERR+++E + + +QL E++ H + Q+ L+E
Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQE 489
Score = 28.1 bits (61), Expect = 4.2
Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 16/107 (14%)
Query: 85 QKKLEAAEERRKSQEAQVLKQLAEKREHEREVL-------------QKALEENNNFSKMA 131
Q+ E +E R+ Q Q +QL E+ E++R++L ++ LEE + A
Sbjct: 361 QENKERSEALRRQQLLQE-QQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREA 419
Query: 132 EEKLILKMEQIKENREANLAAIIERLQEKE--RHAAEVRRNKELQVE 176
+ + + ++ + L + R +E+E R A E +R E + E
Sbjct: 420 RRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQE 466
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.322
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,113,593
Number of Sequences: 37866
Number of extensions: 272319
Number of successful extensions: 5292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 351
Number of HSP's successfully gapped in prelim test: 658
Number of HSP's that attempted gapping in prelim test: 2617
Number of HSP's gapped (non-prelim): 2702
length of query: 179
length of database: 18,247,518
effective HSP length: 96
effective length of query: 83
effective length of database: 14,612,382
effective search space: 1212827706
effective search space used: 1212827706
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.