Search of human proteins with 33188454

Search of human proteins with 33188454

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]
         (142 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]                  290   4e-79
gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]                  179   7e-46
gi|32455266 peroxiredoxin 1 [Homo sapiens]                            145   1e-35
gi|32455264 peroxiredoxin 1 [Homo sapiens]                            145   1e-35
gi|4505591 peroxiredoxin 1 [Homo sapiens]                             145   1e-35
gi|5453549 peroxiredoxin 4 [Homo sapiens]                             128   2e-30
gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo ...   127   3e-30
gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]         118   2e-27
gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]                  118   2e-27
gi|4758638 peroxiredoxin 6 [Homo sapiens]                              53   1e-07
gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]      34   0.036
gi|71834872 tumor differentially expressed 2-like [Homo sapiens]       27   4.4  
gi|6912586 6-phosphogluconolactonase [Homo sapiens]                    27   4.4  
gi|32964823 antimicrobial peptide RYA3 [Homo sapiens]                  27   5.7  
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       26   9.7  
gi|7657307 LIM domains containing 1 [Homo sapiens]                     26   9.7  

>gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]
          Length = 142

 Score =  290 bits (741), Expect = 4e-79
 Identities = 142/142 (100%), Positives = 142/142 (100%)

Query: 1   MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN 60
           MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN
Sbjct: 1   MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN 60

Query: 61  RAEDFRKLGCEVLGVSVDSQFTHLAWYEQGPKREVAAKLTPSGPSSVASWPLLNLWNLRF 120
           RAEDFRKLGCEVLGVSVDSQFTHLAWYEQGPKREVAAKLTPSGPSSVASWPLLNLWNLRF
Sbjct: 61  RAEDFRKLGCEVLGVSVDSQFTHLAWYEQGPKREVAAKLTPSGPSSVASWPLLNLWNLRF 120

Query: 121 PIVKIMETLPPKSLRMMTVISI 142
           PIVKIMETLPPKSLRMMTVISI
Sbjct: 121 PIVKIMETLPPKSLRMMTVISI 142


>gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]
          Length = 198

 Score =  179 bits (454), Expect = 7e-46
 Identities = 88/94 (93%), Positives = 90/94 (95%), Gaps = 1/94 (1%)

Query: 1  MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN 60
          MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN
Sbjct: 1  MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN 60

Query: 61 RAEDFRKLGCEVLGVSVDSQFTHLAWYEQGPKRE 94
          RAEDFRKLGCEVLGVSVDSQFTHLAW    P++E
Sbjct: 61 RAEDFRKLGCEVLGVSVDSQFTHLAWINT-PRKE 93


>gi|32455266 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  145 bits (366), Expect = 1e-35
 Identities = 69/95 (72%), Positives = 82/95 (86%), Gaps = 2/95 (2%)

Query: 1  MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS 59
          M+SGNA+IG PAP+FKATAV+ DG FK++ LSDYKGKYVV FFYPLDFTFVCPTEIIAFS
Sbjct: 1  MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60

Query: 60 NRAEDFRKLGCEVLGVSVDSQFTHLAWYEQGPKRE 94
          +RAE+F+KL C+V+G SVDS F HLAW    PK++
Sbjct: 61 DRAEEFKKLNCQVIGASVDSHFCHLAWVNT-PKKQ 94


>gi|32455264 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  145 bits (366), Expect = 1e-35
 Identities = 69/95 (72%), Positives = 82/95 (86%), Gaps = 2/95 (2%)

Query: 1  MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS 59
          M+SGNA+IG PAP+FKATAV+ DG FK++ LSDYKGKYVV FFYPLDFTFVCPTEIIAFS
Sbjct: 1  MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60

Query: 60 NRAEDFRKLGCEVLGVSVDSQFTHLAWYEQGPKRE 94
          +RAE+F+KL C+V+G SVDS F HLAW    PK++
Sbjct: 61 DRAEEFKKLNCQVIGASVDSHFCHLAWVNT-PKKQ 94


>gi|4505591 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  145 bits (366), Expect = 1e-35
 Identities = 69/95 (72%), Positives = 82/95 (86%), Gaps = 2/95 (2%)

Query: 1  MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS 59
          M+SGNA+IG PAP+FKATAV+ DG FK++ LSDYKGKYVV FFYPLDFTFVCPTEIIAFS
Sbjct: 1  MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS 60

Query: 60 NRAEDFRKLGCEVLGVSVDSQFTHLAWYEQGPKRE 94
          +RAE+F+KL C+V+G SVDS F HLAW    PK++
Sbjct: 61 DRAEEFKKLNCQVIGASVDSHFCHLAWVNT-PKKQ 94


>gi|5453549 peroxiredoxin 4 [Homo sapiens]
          Length = 271

 Score =  128 bits (321), Expect = 2e-30
 Identities = 59/89 (66%), Positives = 73/89 (82%), Gaps = 1/89 (1%)

Query: 6   ARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDF 65
           A+I KPAP ++ TAV+DG FKE+KL+DY+GKY+V FFYPLDFTFVCPTEIIAF +R E+F
Sbjct: 79  AKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEF 138

Query: 66  RKLGCEVLGVSVDSQFTHLAWYEQGPKRE 94
           R +  EV+  SVDSQFTHLAW    P+R+
Sbjct: 139 RSINTEVVACSVDSQFTHLAWINT-PRRQ 166


>gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo
           sapiens]
          Length = 233

 Score =  127 bits (319), Expect = 3e-30
 Identities = 57/81 (70%), Positives = 69/81 (85%)

Query: 6   ARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDF 65
           A+I KPAP ++ TAV+DG FKE+KL+DY+GKY+V FFYPLDFTFVCPTEIIAF +R E+F
Sbjct: 79  AKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEF 138

Query: 66  RKLGCEVLGVSVDSQFTHLAW 86
           R +  EV+  SVDSQFTHLAW
Sbjct: 139 RSINTEVVACSVDSQFTHLAW 159


>gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]
          Length = 256

 Score =  118 bits (295), Expect = 2e-27
 Identities = 52/75 (69%), Positives = 64/75 (85%)

Query: 12  APDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCE 71
           AP FK TAVV+G FK++ L D+KGKY+VLFFYPLDFTFVCPTEI+AFS++A +F  + CE
Sbjct: 69  APYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCE 128

Query: 72  VLGVSVDSQFTHLAW 86
           V+ VSVDS F+HLAW
Sbjct: 129 VVAVSVDSHFSHLAW 143


>gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]
          Length = 238

 Score =  118 bits (295), Expect = 2e-27
 Identities = 52/75 (69%), Positives = 64/75 (85%)

Query: 12  APDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCE 71
           AP FK TAVV+G FK++ L D+KGKY+VLFFYPLDFTFVCPTEI+AFS++A +F  + CE
Sbjct: 51  APYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCE 110

Query: 72  VLGVSVDSQFTHLAW 86
           V+ VSVDS F+HLAW
Sbjct: 111 VVAVSVDSHFSHLAW 125


>gi|4758638 peroxiredoxin 6 [Homo sapiens]
          Length = 224

 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 5/84 (5%)

Query: 4  GNARIGKPAPDFKATAVVDGAFKEVKLSDYKG-KYVVLFFYPLDFTFVCPTEIIAFSNRA 62
          G   +G  AP+F+A   V      ++  D+ G  + +LF +P DFT VC TE+   +  A
Sbjct: 3  GGLLLGDVAPNFEANTTVG----RIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLA 58

Query: 63 EDFRKLGCEVLGVSVDSQFTHLAW 86
           +F K   +++ +S+DS   HLAW
Sbjct: 59 PEFAKRNVKLIALSIDSVEDHLAW 82


>gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]
          Length = 137

 Score = 34.3 bits (77), Expect = 0.036
 Identities = 16/48 (33%), Positives = 26/48 (54%)

Query: 39 VLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAW 86
          +LF +P D   VC  E+   +  A +F K   +++ ++ DS   HLAW
Sbjct: 34 ILFSHPRDSKPVCTMELGRAAKLAPEFTKSNVKLIALATDSAEDHLAW 81


>gi|71834872 tumor differentially expressed 2-like [Homo sapiens]
          Length = 455

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 70  CEVLGVSVDSQFTHLAWYEQGPKREVAAKLTPSGPSSVASWP--LLNLWNLRFPIV 123
           C VL  S+    T   WY+ G  R++ +  T       ASW   LL LW L  P++
Sbjct: 394 CLVLA-SLHVMMTLTNWYKPGETRKMISTWTAVWVKICASWAGLLLYLWTLVAPLL 448


>gi|6912586 6-phosphogluconolactonase [Homo sapiens]
          Length = 258

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 7/40 (17%)

Query: 73  LGVSVDSQFTHLAWYEQGPKREVAAKLTPSGPSSVASWPL 112
           LG+S  S  + LA       RE+ A + P+GP+S+A W L
Sbjct: 43  LGLSGGSLVSMLA-------RELPAAVAPAGPASLARWTL 75


>gi|32964823 antimicrobial peptide RYA3 [Homo sapiens]
          Length = 476

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 11/26 (42%), Positives = 16/26 (61%)

Query: 104 PSSVASWPLLNLWNLRFPIVKIMETL 129
           P  +A W LL LW L  P  +++ET+
Sbjct: 3   PVMLALWSLLLLWGLATPCQELLETV 28


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 26.2 bits (56), Expect = 9.7
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 1/42 (2%)

Query: 102  SGPSSVASWPLLNLWN-LRFPIVKIMETLPPKSLRMMTVISI 142
            + P S+ + PL  L N L  P+++    L  K LR++++ISI
Sbjct: 3421 TSPYSLEASPLGQLMNMLSHPVIRRSSLLTEKLLRLLSLISI 3462


>gi|7657307 LIM domains containing 1 [Homo sapiens]
          Length = 676

 Score = 26.2 bits (56), Expect = 9.7
 Identities = 12/40 (30%), Positives = 19/40 (47%)

Query: 68  LGCEVLGVSVDSQFTHLAWYEQGPKREVAAKLTPSGPSSV 107
           LG EV GV          W++ GPK  +++    S P+ +
Sbjct: 318 LGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGL 357


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,433,830
Number of Sequences: 37866
Number of extensions: 209654
Number of successful extensions: 456
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 438
Number of HSP's gapped (non-prelim): 17
length of query: 142
length of database: 18,247,518
effective HSP length: 92
effective length of query: 50
effective length of database: 14,763,846
effective search space: 738192300
effective search space used: 738192300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.