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Search of human proteins with 31881675
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
(421 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 862 0.0
gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 764 0.0
gi|209447073 synaptotagmin I [Homo sapiens] 177 2e-44
gi|5032139 synaptotagmin I [Homo sapiens] 177 2e-44
gi|209447070 synaptotagmin I [Homo sapiens] 177 2e-44
gi|211059429 synaptotagmin II [Homo sapiens] 174 1e-43
gi|31543670 synaptotagmin II [Homo sapiens] 174 1e-43
gi|92859638 synaptotagmin V [Homo sapiens] 172 4e-43
gi|28376627 synaptotagmin IX [Homo sapiens] 169 4e-42
gi|39752671 synaptotagmin X [Homo sapiens] 166 5e-41
gi|238550198 synaptotagmin III [Homo sapiens] 165 8e-41
gi|238550196 synaptotagmin III [Homo sapiens] 165 8e-41
gi|14150054 synaptotagmin III [Homo sapiens] 165 8e-41
gi|45504376 synaptotagmin VI [Homo sapiens] 162 4e-40
gi|38570146 synaptotagmin VII [Homo sapiens] 153 3e-37
gi|169184624 PREDICTED: similar to synaptotagmin XV-b [Homo sapi... 147 2e-35
gi|40068038 B/K protein [Homo sapiens] 145 7e-35
gi|24308219 synaptotagmin IV [Homo sapiens] 137 1e-32
gi|216548478 synaptotagmin XI [Homo sapiens] 127 2e-29
gi|29366828 synaptotagmin XII [Homo sapiens] 115 7e-26
gi|94536846 synaptotagmin VIII [Homo sapiens] 107 2e-23
gi|6005997 double C2-like domains, beta [Homo sapiens] 103 2e-22
gi|24308233 synaptotagmin XIII [Homo sapiens] 99 6e-21
gi|47078261 double C2-like domains, alpha [Homo sapiens] 97 3e-20
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 92 9e-19
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 92 9e-19
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 87 4e-17
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 87 4e-17
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 83 5e-16
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 83 5e-16
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 862 bits (2228), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP
Sbjct: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
Query: 61 CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD 120
CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD
Sbjct: 61 CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD 120
Query: 121 ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET 180
ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET
Sbjct: 121 ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET 180
Query: 181 CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK 240
CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK
Sbjct: 181 CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK 240
Query: 241 HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL
Sbjct: 241 HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
Query: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT
Sbjct: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
Query: 361 ASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHALCRTTE 420
ASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHALCRTTE
Sbjct: 361 ASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHALCRTTE 420
Query: 421 P 421
P
Sbjct: 421 P 421
>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
Length = 390
Score = 764 bits (1974), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP
Sbjct: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
Query: 61 CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD 120
CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD
Sbjct: 61 CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD 120
Query: 121 ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET 180
ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET
Sbjct: 121 ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET 180
Query: 181 CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK 240
CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK
Sbjct: 181 CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK 240
Query: 241 HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL
Sbjct: 241 HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
Query: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT
Sbjct: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
Query: 361 ASLSLTVVQNMEGDK 375
ASLSLTVVQNMEGDK
Sbjct: 361 ASLSLTVVQNMEGDK 375
Score = 33.5 bits (75), Expect = 0.37
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 12/119 (10%)
Query: 269 EAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLM-NHNK 327
++E+ P G L F + Y RL V +++A+ LQ S VK+ L+ + +
Sbjct: 138 KSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQ--HLQAPSETCSPLVKLYLLPDERR 195
Query: 328 FVKCK---KTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVV 383
F++ K KTS NP ++E F F+ + + L +V K Q LG+V+
Sbjct: 196 FLQSKTKRKTS------NPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVL 248
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 177 bits (449), Expect = 2e-44
Identities = 102/292 (34%), Positives = 162/292 (55%), Gaps = 16/292 (5%)
Query: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183
+D +ET DG LG+L +S++Y+ + +LLVG+I+A L A T P
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
Query: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
VK++LLPD+++ ++K RKT NP F+E F F+V + + L +VY DR KH +
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303
+G+ P+ N G WRDL++ E + GD+ F L Y +LTVV+L AK
Sbjct: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
Query: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363
L+ + G+ +VK+ LM + K +K KKT+ ++NP YNE+FSF+ ++ +
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
Query: 364 SLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
+TV+ + K+ +G+V VG + G EL HW +ML+ P+ + +WH L
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVG--YNSTGAELRHWSDMLANPRRPIAQWHTL 408
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 269 EAESLEPPSE---FGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325
+ E E P E G LQ+ L Y+ ++L V +++A L + G +VKV L+
Sbjct: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
Query: 326 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVG 385
K K +T ++NPV+NE F+FK +EL +L + V K +G V
Sbjct: 190 KK--KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP 247
Query: 386 PYMYTRGRELEHWDEMLSKPKELVKRWHALC 416
G E W ++ S KE ++ +C
Sbjct: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDIC 278
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 177 bits (449), Expect = 2e-44
Identities = 102/292 (34%), Positives = 162/292 (55%), Gaps = 16/292 (5%)
Query: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183
+D +ET DG LG+L +S++Y+ + +LLVG+I+A L A T P
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
Query: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
VK++LLPD+++ ++K RKT NP F+E F F+V + + L +VY DR KH +
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303
+G+ P+ N G WRDL++ E + GD+ F L Y +LTVV+L AK
Sbjct: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
Query: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363
L+ + G+ +VK+ LM + K +K KKT+ ++NP YNE+FSF+ ++ +
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
Query: 364 SLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
+TV+ + K+ +G+V VG + G EL HW +ML+ P+ + +WH L
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVG--YNSTGAELRHWSDMLANPRRPIAQWHTL 408
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 269 EAESLEPPSE---FGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325
+ E E P E G LQ+ L Y+ ++L V +++A L + G +VKV L+
Sbjct: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
Query: 326 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVG 385
K K +T ++NPV+NE F+FK +EL +L + V K +G V
Sbjct: 190 KK--KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP 247
Query: 386 PYMYTRGRELEHWDEMLSKPKELVKRWHALC 416
G E W ++ S KE ++ +C
Sbjct: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDIC 278
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 177 bits (449), Expect = 2e-44
Identities = 102/292 (34%), Positives = 162/292 (55%), Gaps = 16/292 (5%)
Query: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183
+D +ET DG LG+L +S++Y+ + +LLVG+I+A L A T P
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
Query: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
VK++LLPD+++ ++K RKT NP F+E F F+V + + L +VY DR KH +
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303
+G+ P+ N G WRDL++ E + GD+ F L Y +LTVV+L AK
Sbjct: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
Query: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363
L+ + G+ +VK+ LM + K +K KKT+ ++NP YNE+FSF+ ++ +
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
Query: 364 SLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
+TV+ + K+ +G+V VG + G EL HW +ML+ P+ + +WH L
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVG--YNSTGAELRHWSDMLANPRRPIAQWHTL 408
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 269 EAESLEPPSE---FGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325
+ E E P E G LQ+ L Y+ ++L V +++A L + G +VKV L+
Sbjct: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
Query: 326 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVG 385
K K +T ++NPV+NE F+FK +EL +L + V K +G V
Sbjct: 190 KK--KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP 247
Query: 386 PYMYTRGRELEHWDEMLSKPKELVKRWHALC 416
G E W ++ S KE ++ +C
Sbjct: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDIC 278
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 174 bits (442), Expect = 1e-43
Identities = 95/282 (33%), Positives = 159/282 (56%), Gaps = 6/282 (2%)
Query: 136 EDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSPLVKLYLLPDE 193
E + E + LG+L FS++Y+ +A +L VG+++A L A T P VK++LLPD+
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
Query: 194 RRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253
++ ++K RKT NP F+E F F+V + + + L ++Y DR KH ++G+V P+
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
Query: 254 ETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGI 313
L WRDL+ E P + GD+ L Y +LTV +L AK L+ + G+
Sbjct: 248 VDLGQPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
Query: 314 VSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEG 373
+VK+ LM + K +K KKT+ ++NP +NE+FSF+ ++ + +TV+ +
Sbjct: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
Query: 374 DKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
K++ +G++ VG G EL HW +ML+ P+ + +WH+L
Sbjct: 366 GKNEAIGKIFVG--SNATGTELRHWSDMLANPRRPIAQWHSL 405
Score = 65.1 bits (157), Expect = 1e-10
Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 269 EAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKF 328
E E + P G LQF L Y+ ++LTV VL+A L + G +VKV L+ K
Sbjct: 130 EGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKK- 188
Query: 329 VKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYM 388
K +T ++NP +NETF+FK EL +L + + K +G V V
Sbjct: 189 -KKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
Query: 389 YTRGRELEHWDEMLSKPKELVKRWHALC 416
G+ +E W ++ KE ++ +C
Sbjct: 248 VDLGQPIEEWRDLQGGEKEEPEKLGDIC 275
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 174 bits (442), Expect = 1e-43
Identities = 95/282 (33%), Positives = 159/282 (56%), Gaps = 6/282 (2%)
Query: 136 EDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSPLVKLYLLPDE 193
E + E + LG+L FS++Y+ +A +L VG+++A L A T P VK++LLPD+
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
Query: 194 RRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253
++ ++K RKT NP F+E F F+V + + + L ++Y DR KH ++G+V P+
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
Query: 254 ETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGI 313
L WRDL+ E P + GD+ L Y +LTV +L AK L+ + G+
Sbjct: 248 VDLGQPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
Query: 314 VSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEG 373
+VK+ LM + K +K KKT+ ++NP +NE+FSF+ ++ + +TV+ +
Sbjct: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
Query: 374 DKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
K++ +G++ VG G EL HW +ML+ P+ + +WH+L
Sbjct: 366 GKNEAIGKIFVG--SNATGTELRHWSDMLANPRRPIAQWHSL 405
Score = 65.1 bits (157), Expect = 1e-10
Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 269 EAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKF 328
E E + P G LQF L Y+ ++LTV VL+A L + G +VKV L+ K
Sbjct: 130 EGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKK- 188
Query: 329 VKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYM 388
K +T ++NP +NETF+FK EL +L + + K +G V V
Sbjct: 189 -KKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
Query: 389 YTRGRELEHWDEMLSKPKELVKRWHALC 416
G+ +E W ++ KE ++ +C
Sbjct: 248 VDLGQPIEEWRDLQGGEKEEPEKLGDIC 275
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 172 bits (437), Expect = 4e-43
Identities = 98/270 (36%), Positives = 155/270 (57%), Gaps = 6/270 (2%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPS--ETCSPLVKLYLLPDERRFLQSKTKRKT 205
LGRL +S++Y+ ++ +LLVG+++A L A + P V++YLLPD+RR ++K R+T
Sbjct: 109 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT 168
Query: 206 SNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIW 265
NP F E F F+V + RVL +VY DR ++ +G+V P+ + L + W
Sbjct: 169 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQA--W 226
Query: 266 RDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325
R+L+A E + GD+ F L Y +LTV+VL AK L+ + G+ +VKV L+
Sbjct: 227 RELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQG 286
Query: 326 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVG 385
K V+ KKT+ ++NP YNE FSF+ ++ + LTV+ + K++ +GRV VG
Sbjct: 287 GKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVG 346
Query: 386 PYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
G L HW +ML+ P+ + +WH+L
Sbjct: 347 --AAAGGAGLRHWADMLANPRRPIAQWHSL 374
Score = 56.6 bits (135), Expect = 4e-08
Identities = 45/159 (28%), Positives = 73/159 (45%), Gaps = 13/159 (8%)
Query: 269 EAESLEP-PS----------EFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVF 317
E E LEP PS E G LQ+ L Y+ +L V +L+A GL + G +
Sbjct: 88 EVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPY 147
Query: 318 VKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQ 377
V+V L+ + + +T ++NP + ETF+FK EL L + V ++
Sbjct: 148 VRVYLLPDKR--RRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRND 205
Query: 378 QLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHALC 416
+G V V GR ++ W E+ + P+E ++ +C
Sbjct: 206 AIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDIC 244
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 169 bits (428), Expect = 4e-42
Identities = 108/299 (36%), Positives = 158/299 (52%), Gaps = 13/299 (4%)
Query: 124 VGAINPELYK---FPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAP--S 178
+G I PELYK D C G+L F ++Y+ + E+L+V + KA +L A S
Sbjct: 195 IGRIKPELYKQRSLDNDDGRRSNSKAC-GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFS 253
Query: 179 ETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQ 238
T P VK+YLLPD + Q+K RKT NP FDE F+F V + R L FSVY DR
Sbjct: 254 GTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRF 313
Query: 239 RKHQLLGQVLFP--LKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLT 296
+H L+GQV+ L +C ++W+D+E + + G+L F L Y RLT
Sbjct: 314 SRHDLIGQVVVDHFLDLADFPREC--ILWKDIEYVT-NDNVDLGELMFSLCYLPTAGRLT 370
Query: 297 VVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADAT 356
+ +++A+ L+ + G +VKVSLM + +K +KTS ++NPVYNE F
Sbjct: 371 ITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPE 430
Query: 357 ELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
+D LS+ V+ ++ +G VG GR +HW EMLS P++ + WH+L
Sbjct: 431 NIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DHWSEMLSYPRKPIAHWHSL 487
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 166 bits (419), Expect = 5e-41
Identities = 103/298 (34%), Positives = 161/298 (54%), Gaps = 11/298 (3%)
Query: 124 VGAINPELYKFPEDKSETDFPDGC--LGRLWFSVEYEQEAERLLVGLIKAQHLQAP--SE 179
+G I PELYK SE + + G+L F+++Y+ E E L+V +IKA L A +
Sbjct: 206 IGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTG 265
Query: 180 TCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQR 239
T P VK+YLLPD ++ Q++ RKT NP FDE F F V+ ++ R L FSVY DR
Sbjct: 266 TSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFS 325
Query: 240 KHQLLGQVLFPLKNETLVGDCRR--VIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297
+H ++G+V+ L N V D R +W+D+ + E + G++ F L Y R+T+
Sbjct: 326 RHDMIGEVI--LDNLFEVSDLSREATVWKDIHCATTE-SIDLGEIMFSLCYLPTAGRMTL 382
Query: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE 357
V++ + L+ + G +VKVSLM + +K +KT+ ++NPVYNE F
Sbjct: 383 TVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPEN 442
Query: 358 LDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
+D SLS+ V+ ++ +G G + G +HW+EML+ ++ + WH L
Sbjct: 443 VDQVSLSIAVMDYDRVGHNEVIGVCRTG--LDAEGLGRDHWNEMLAYHRKPITHWHPL 498
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 165 bits (417), Expect = 8e-41
Identities = 113/329 (34%), Positives = 165/329 (50%), Gaps = 19/329 (5%)
Query: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149
P P+SE LP GG A ++G I PELY+ P + P G
Sbjct: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
Query: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207
R+ F++ Y +++L+V +++A L A P VK+YLLPD ++ Q+K RKT N
Sbjct: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
Query: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267
P F+E F F V + QR L FSVY DR +H L+GQV+ E R +WRD
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
Query: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327
+ E ++ G+L F L Y RLTV +++A L+ + G +VK SL++ +
Sbjct: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
Query: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGP- 386
+K +KTS ++NP YNE F ++ LS+ VV ++ +G VGP
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
Query: 387 YMYTRGRELEHWDEMLSKPKELVKRWHAL 415
GR EHW EML+ P++ V+ WH L
Sbjct: 541 AADPHGR--EHWAEMLANPRKPVEHWHQL 567
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 165 bits (417), Expect = 8e-41
Identities = 113/329 (34%), Positives = 165/329 (50%), Gaps = 19/329 (5%)
Query: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149
P P+SE LP GG A ++G I PELY+ P + P G
Sbjct: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
Query: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207
R+ F++ Y +++L+V +++A L A P VK+YLLPD ++ Q+K RKT N
Sbjct: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
Query: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267
P F+E F F V + QR L FSVY DR +H L+GQV+ E R +WRD
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
Query: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327
+ E ++ G+L F L Y RLTV +++A L+ + G +VK SL++ +
Sbjct: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
Query: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGP- 386
+K +KTS ++NP YNE F ++ LS+ VV ++ +G VGP
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
Query: 387 YMYTRGRELEHWDEMLSKPKELVKRWHAL 415
GR EHW EML+ P++ V+ WH L
Sbjct: 541 AADPHGR--EHWAEMLANPRKPVEHWHQL 567
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 165 bits (417), Expect = 8e-41
Identities = 113/329 (34%), Positives = 165/329 (50%), Gaps = 19/329 (5%)
Query: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149
P P+SE LP GG A ++G I PELY+ P + P G
Sbjct: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
Query: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207
R+ F++ Y +++L+V +++A L A P VK+YLLPD ++ Q+K RKT N
Sbjct: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
Query: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267
P F+E F F V + QR L FSVY DR +H L+GQV+ E R +WRD
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
Query: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327
+ E ++ G+L F L Y RLTV +++A L+ + G +VK SL++ +
Sbjct: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
Query: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGP- 386
+K +KTS ++NP YNE F ++ LS+ VV ++ +G VGP
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPD 540
Query: 387 YMYTRGRELEHWDEMLSKPKELVKRWHAL 415
GR EHW EML+ P++ V+ WH L
Sbjct: 541 AADPHGR--EHWAEMLANPRKPVEHWHQL 567
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 162 bits (411), Expect = 4e-40
Identities = 101/299 (33%), Positives = 163/299 (54%), Gaps = 13/299 (4%)
Query: 124 VGAINPELYKFPE---DKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPS-- 178
+G I PELYK + ++++ C G++ FS+ Y+ E E L+V ++KA L A
Sbjct: 119 IGRIKPELYKQKSVDGEDAKSEATKSC-GKINFSLRYDYETETLIVRILKAFDLPAKDFC 177
Query: 179 ETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQ 238
+ P VK+YLLPD + LQ++ RKT NP FDE+F F V + + R L SV+ DR
Sbjct: 178 GSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRF 237
Query: 239 RKHQLLGQVLFPLKNETLVGDCRR--VIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLT 296
+H ++G+V+ L N D R IW+D++ + E + G++ F L Y RLT
Sbjct: 238 SRHDMIGEVI--LDNLFEASDLSRETSIWKDIQYATSE-SVDLGEIMFSLCYLPTAGRLT 294
Query: 297 VVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADAT 356
+ V++ + L+ + G +VKVSL+ + +K KKT+ ++NPVYNE F
Sbjct: 295 LTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPE 354
Query: 357 ELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
+D SL ++V+ ++ +G VG + G +HW+EML+ P++ + WH+L
Sbjct: 355 NMDQVSLLISVMDYDRVGHNEIIGVCRVG--ITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 153 bits (386), Expect = 3e-37
Identities = 92/300 (30%), Positives = 163/300 (54%), Gaps = 12/300 (4%)
Query: 123 MVGAINPELYKFPEDKSETDFPDGC----LGRLWFSVEYEQEAERLLVGLIKAQHLQAP- 177
+V ++ E+ E + +GC LGR+ FSV Y + L V ++KAQ L A
Sbjct: 107 LVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKD 166
Query: 178 -SETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHV 235
S T P VK+YLLPD++ L++K KRK NP ++E F+F+ + + QR+L V
Sbjct: 167 FSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDY 226
Query: 236 DRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRL 295
DR ++ +G+V PL L + W+DL+ S + G+L L YN + +
Sbjct: 227 DRFSRNDPIGEVSIPLNKVDLTQ--MQTFWKDLKPCS-DGSGSRGELLLSLCYNPSANSI 283
Query: 296 TVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADA 355
V +++A+ L+ + G +VKV LM +K V+ KKT + ++NP++NE+F+F
Sbjct: 284 IVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPT 343
Query: 356 TELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
+L ++ +TV+ + ++ +G++ + + E++HW +M+++P++ V +WH L
Sbjct: 344 EKLRETTIIITVMDKDKLSRNDVIGKIYLS--WKSGPGEVKHWKDMIARPRQPVAQWHQL 401
>gi|169184624 PREDICTED: similar to synaptotagmin XV-b [Homo
sapiens]
Length = 267
Score = 147 bits (370), Expect = 2e-35
Identities = 71/71 (100%), Positives = 71/71 (100%)
Query: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP
Sbjct: 197 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 256
Query: 61 CQPHARTQLSR 71
CQPHARTQLSR
Sbjct: 257 CQPHARTQLSR 267
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 145 bits (366), Expect = 7e-35
Identities = 96/277 (34%), Positives = 141/277 (50%), Gaps = 13/277 (4%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET---------CSPLVKLYLLPDERRFLQ 198
LG L FS +Y+ L V +I+A+ L P +P VK+ LLPD++ Q
Sbjct: 185 LGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQ 244
Query: 199 SKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVG 258
+ KRKT P F+E + F++ +R L +V D+ +H ++G+V PL LV
Sbjct: 245 TGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVK 304
Query: 259 DCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFV 318
W S + E G+L L+Y RL V V+RAK L + FV
Sbjct: 305 GGH---WWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFV 361
Query: 319 KVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQ 378
K+ L++ K VK KKTS + G+I+P YNE+FSFK EL+ ASL TV + +
Sbjct: 362 KIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDF 421
Query: 379 LGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
+GR+V+G Y + E HW ML+ + V++WH+L
Sbjct: 422 IGRIVIGQYS-SGPSETNHWRRMLNTHRTAVEQWHSL 457
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 137 bits (346), Expect = 1e-32
Identities = 84/273 (30%), Positives = 145/273 (53%), Gaps = 7/273 (2%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSE---TCSPLVKLYLLPDERRFLQSKTKRK 204
LG L+FS+EY E + +V + +A+ L A E T P +K+ +LP+++ ++++ RK
Sbjct: 154 LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRK 213
Query: 205 TSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRV 263
T +P FDE F F + I + L F++ DR + ++G+VL PL L + + +
Sbjct: 214 TLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIEL-SEGKML 272
Query: 264 IWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLM 323
+ R++ ++ S G+L L Y + LTVVVL+A+ L + G+ +VKV+L
Sbjct: 273 MNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLY 332
Query: 324 NHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVV 383
+ K + KKT + N V+NE F F L+ S+ V+ + G +++ +G++V
Sbjct: 333 HAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLV 392
Query: 384 VGPYMYTRGRELEHWDEMLSKPKELVKRWHALC 416
+G G EHW E+ P+ + +WH LC
Sbjct: 393 LG--AAAEGTGGEHWKEICDYPRRQIAKWHVLC 423
Score = 40.4 bits (93), Expect = 0.003
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 10/142 (7%)
Query: 272 SLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVS-VFVKVSLMNHNKFVK 330
S E + G L F L YN V + A+GL +++ + S ++K++++ K
Sbjct: 147 SEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHK- 205
Query: 331 CKKTSAVLGSINPVYNETFSFKA-DATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMY 389
KT + +++P ++ETF+F T++ +L T++ + +G V++
Sbjct: 206 -VKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIP---- 260
Query: 390 TRGRELEHWDEMLSKPKELVKR 411
G EL +++ +E++KR
Sbjct: 261 LSGIELSEGKMLMN--REIIKR 280
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 127 bits (318), Expect = 2e-29
Identities = 84/277 (30%), Positives = 145/277 (52%), Gaps = 9/277 (3%)
Query: 145 DGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA---PSETCSPLVKLYLLPDERRFLQSKT 201
D LG L FSV+Y + L+V + +A L ++ P +K+ +LPD+R ++++
Sbjct: 155 DVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRV 214
Query: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN-ETLVGD 259
RKT +P FDE F F + + VL F V DR + ++G+V+ PL + G
Sbjct: 215 LRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGK 274
Query: 260 CRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIV-SVFV 318
+ + RD+ +++ G+LQ LSY R+TVVVL+A+ L + G+ + +V
Sbjct: 275 VQ--LTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYV 332
Query: 319 KVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQ 378
KV++ K + KKT ++NP++NE+F + L S+ V+ K++
Sbjct: 333 KVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEV 392
Query: 379 LGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
+GR+++G + T EHW E+ P++ V +WH+L
Sbjct: 393 VGRLILGAHSVT-ASGAEHWREVCESPRKPVAKWHSL 428
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 115 bits (288), Expect = 7e-26
Identities = 84/288 (29%), Positives = 139/288 (48%), Gaps = 20/288 (6%)
Query: 139 SETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHL----QAPSETCSPLVKLYLLPDER 194
S T D LG++ S+EY+ + L V +++ + L +A E+C +++ LLPDE+
Sbjct: 144 SNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESC--FMRVSLLPDEQ 201
Query: 195 RFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQV-----LF 249
S+ +R + FDE F + + ++ L+FSV+ +D ++ G V +
Sbjct: 202 IVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVL 261
Query: 250 PLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQE 309
L + G W L+ ++ + G++ LSY RLTVVV++AK L
Sbjct: 262 DLPLQPFSG------WLYLQDQN-KAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTN 314
Query: 310 DRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQ 369
D+ FVKV L+ + + KKT+ NPV+NE F A L SL +TV +
Sbjct: 315 DKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAE 374
Query: 370 NMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHALCR 417
+ + +G V++GP G HW++ML+ + V WHA+ R
Sbjct: 375 SSSDGRGDNVGHVIIGP--SASGMGTTHWNQMLATLRRPVSMWHAVRR 420
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 107 bits (267), Expect = 2e-23
Identities = 78/269 (28%), Positives = 131/269 (48%), Gaps = 13/269 (4%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKTKRKTSNP 208
GRL S+E++ ++ + VGL +A L+ P T P ++ + ++K R T P
Sbjct: 119 GRLQLSLEFDFGSQEIRVGLRQAADLR-PGGTVDPYARVSVSTQAGHRHETKVHRGTLCP 177
Query: 209 QFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVI--WR 266
FDE F + + L+ +++ R H+ LG++ PL D + V+ W
Sbjct: 178 VFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV----DLQHVLEHWY 233
Query: 267 DLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHN 326
L + P + G+L F L Y RLTVVVL A+GLR G+ +VKV LM +
Sbjct: 234 LLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PGLAEPYVKVQLMLNQ 289
Query: 327 KFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGP 386
+ K +KT+ G+ P +NE F+F +++ L L V +++ +G+V +G
Sbjct: 290 RKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLG- 348
Query: 387 YMYTRGRELEHWDEMLSKPKELVKRWHAL 415
G+ L+HW +ML+ + + + H L
Sbjct: 349 -ARASGQPLQHWADMLAHARRPIAQRHPL 376
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 103 bits (258), Expect = 2e-22
Identities = 86/298 (28%), Positives = 141/298 (47%), Gaps = 19/298 (6%)
Query: 133 KFPEDKSETDF--PDGC--LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVK 186
K PED+ + D D C LG L FS+ Y+QE L + KA+ L+ P VK
Sbjct: 108 KPPEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVK 167
Query: 187 LYLLPDERRF--LQSKTKRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQL 243
L+LLP + L++KT R T NP ++E + ++ + + ++ L+ SV D+ R ++
Sbjct: 168 LHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEF 227
Query: 244 LGQVLFPLK----NETLVGDCRRVIWRDLEAESLEPPS--EFGDLQFCLSYNDYLSRLTV 297
+G+ PLK N T + + + L + E S E G + L Y+ L V
Sbjct: 228 IGETRVPLKKLKPNHTKTFNI--CLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLV 285
Query: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE 357
++R L + G +VK L KT+ ++NP +NE F ++ +
Sbjct: 286 GIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGD 345
Query: 358 LDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
L SL +TV G + +G VV+G ++ +G L+HW + L + ++RWH L
Sbjct: 346 LAKKSLEVTVWDYDIGKSNDFIGGVVLG--IHAKGERLKHWFDCLKNKDKRIERWHTL 401
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 99.4 bits (246), Expect = 6e-21
Identities = 100/437 (22%), Positives = 185/437 (42%), Gaps = 48/437 (10%)
Query: 7 LVIGGTIGGLLLLLLIGASCCLWRRFC---ATLTYEELPGTPAMATTAASSGQR------ 57
+ +G T+G +L + CL R L ++ P + S Q+
Sbjct: 8 IALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDQDPDLEKAKPSLLGSAQQFNVKKS 67
Query: 58 DRPCQPHARTQLSR--PPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPAS-------- 107
P QP A + P P + D+ L S E AP P P +
Sbjct: 68 TEPVQPRALLKFPDIYGPRPAVTAPEVINYADY-SLRSTEEPTAPASPQPPNDSRLKRQV 126
Query: 108 --ELLPHTSSGGLGDACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLL 165
EL +G + D C++ NPE + S P +L + ++Y+ + L
Sbjct: 127 TEELFILPQNGVVEDVCVMETWNPE-----KAASWNQAP-----KLHYCLDYDCQKAELF 176
Query: 166 VGLIKAQHLQAPSETCSPLVKLYL---LPDERRFLQSKT--KRKTSNPQFDEHFIFQVSS 220
V L+A + Y+ + + ++++T K++ + ++E + ++
Sbjct: 177 V-----TRLEAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAE 231
Query: 221 KTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFG 280
+ + L ++ DR +H + G++ L ++ + W +L+ + EP + G
Sbjct: 232 EELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQ--WGELKTSAKEPSAGAG 289
Query: 281 DLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVS--VFVKVSLMNHNKFVKCKKTSAVL 338
++ +SY +RL VV+++AK L + + ++ V VKV+L + + +K K+T
Sbjct: 290 EVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAK 349
Query: 339 GSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHW 398
INPV+NE F+ L +S+ L V+ + +S LG +G ++T G E HW
Sbjct: 350 HKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLG--LHTSGSERSHW 407
Query: 399 DEMLSKPKELVKRWHAL 415
+EML P+ + WH L
Sbjct: 408 EEMLKNPRRQIAMWHQL 424
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 97.1 bits (240), Expect = 3e-20
Identities = 84/322 (26%), Positives = 140/322 (43%), Gaps = 37/322 (11%)
Query: 135 PEDKSETDFPDG----CLGRLWFSVEYEQEAERLLVGLIKAQHLQAP--SETCSPLVKLY 188
PED +E D D LG L F + Y++ + L +++A+ L+ + P VKL+
Sbjct: 73 PEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLH 132
Query: 189 LLPD--ERRFLQSKTKRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLG 245
LLP + L++KT+R T NP ++E + ++ IT +VL+ +V D+ ++ +G
Sbjct: 133 LLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIG 192
Query: 246 QVLFPLKN----------------------ETLVGDCRRVIWRDLEAESLEPPS----EF 279
++ PL+ ++ R + E E E E
Sbjct: 193 EIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEER 252
Query: 280 GDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLG 339
G + LSY+ L V +LR L + G +VK L KT
Sbjct: 253 GRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKK 312
Query: 340 SINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWD 399
++NP +NE F ++ + + L T +L +TV G + +G V +GP RG +HW
Sbjct: 313 TLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGP--GARGEARKHWS 370
Query: 400 EMLSKPKELVKRWHALCRTTEP 421
+ L +P ++RWH L P
Sbjct: 371 DCLQQPDAALERWHTLTSELPP 392
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 92.0 bits (227), Expect = 9e-19
Identities = 75/295 (25%), Positives = 131/295 (44%), Gaps = 29/295 (9%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRF--LQSKTKR 203
LG L FS+ Y+Q+ L +IKA+ L+ P VKL+LLP + L++KT R
Sbjct: 393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLR 452
Query: 204 KTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLF------------- 249
T NP ++E ++ ++ + + ++ L+ SV D+ ++ +G+ F
Sbjct: 453 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 512
Query: 250 --------PLKNETLVGDCRRV-IWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
P+K G R + ++ + + E + E G + L Y+ L V ++
Sbjct: 513 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGII 572
Query: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
R L + G FVK+ L KT ++NP +NE F + ++L
Sbjct: 573 RCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAK 632
Query: 361 ASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
SL ++V G + +G +G + +G L+HW E L + ++RWH L
Sbjct: 633 KSLDISVWDYDIGKSNDYIGGCQLG--ISAKGERLKHWYECLKNKDKKIERWHQL 685
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 92.0 bits (227), Expect = 9e-19
Identities = 75/295 (25%), Positives = 131/295 (44%), Gaps = 29/295 (9%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRF--LQSKTKR 203
LG L FS+ Y+Q+ L +IKA+ L+ P VKL+LLP + L++KT R
Sbjct: 389 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLR 448
Query: 204 KTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLF------------- 249
T NP ++E ++ ++ + + ++ L+ SV D+ ++ +G+ F
Sbjct: 449 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 508
Query: 250 --------PLKNETLVGDCRRV-IWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
P+K G R + ++ + + E + E G + L Y+ L V ++
Sbjct: 509 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGII 568
Query: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
R L + G FVK+ L KT ++NP +NE F + ++L
Sbjct: 569 RCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAK 628
Query: 361 ASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
SL ++V G + +G +G + +G L+HW E L + ++RWH L
Sbjct: 629 KSLDISVWDYDIGKSNDYIGGCQLG--ISAKGERLKHWYECLKNKDKKIERWHQL 681
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 86.7 bits (213), Expect = 4e-17
Identities = 81/293 (27%), Positives = 122/293 (41%), Gaps = 36/293 (12%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSET---CSPLVKLYLLPDERRFLQSKT--KR 203
GR+ FS++YEQ+ + L+V + + L E +P VK YLLPD+ R + KT KR
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPL---KNETLVGDC 260
T NP +DE +++ + QR L+FSV+H R ++ LG+ + K + + C
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 261 RRVIWRDLEAESLEPPSEFGDLQFCLSY----------------NDYLSRLTVVVLRAKG 304
+ + PS G+L L Y L V + AK
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 305 LRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE-LDTASL 363
L + G FVK L+ +KT + ++NP YN TF + E L L
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 364 SLTVVQNMEGDKSQQLGRVVVG-----------PYMYTRGRELEHWDEMLSKP 405
LTV + LG V +G +M + G E+ W +M P
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 86.7 bits (213), Expect = 4e-17
Identities = 81/293 (27%), Positives = 122/293 (41%), Gaps = 36/293 (12%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSET---CSPLVKLYLLPDERRFLQSKT--KR 203
GR+ FS++YEQ+ + L+V + + L E +P VK YLLPD+ R + KT KR
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPL---KNETLVGDC 260
T NP +DE +++ + QR L+FSV+H R ++ LG+ + K + + C
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 261 RRVIWRDLEAESLEPPSEFGDLQFCLSY----------------NDYLSRLTVVVLRAKG 304
+ + PS G+L L Y L V + AK
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 305 LRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE-LDTASL 363
L + G FVK L+ +KT + ++NP YN TF + E L L
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 364 SLTVVQNMEGDKSQQLGRVVVG-----------PYMYTRGRELEHWDEMLSKP 405
LTV + LG V +G +M + G E+ W +M P
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650
>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
Length = 600
Score = 82.8 bits (203), Expect = 5e-16
Identities = 80/301 (26%), Positives = 133/301 (44%), Gaps = 34/301 (11%)
Query: 144 PDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETC--SPLVKLYLLPDERRFLQSKT 201
P+ G L + +Y+ + ++LLV + + + T S V L LLP +++ ++
Sbjct: 302 PEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSI 361
Query: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDC 260
+R P F E F F V S+ I ++F +Y V R +K +++G+ +F L L G
Sbjct: 362 QRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420
Query: 261 RRVIWRD-----------------------LEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297
+ + +SLE S ++ L YN RL+
Sbjct: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGS-VPEILIGLLYNATTGRLSA 479
Query: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNH--NKFVKCKKTSAVLGSINPVYNETFSFKADA 355
V++ + + +VK++L+N + KCK TS G NPVY ETF F+
Sbjct: 480 EVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK-TSIRRGQPNPVYKETFVFQVAL 538
Query: 356 TELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRG-RELEHWDEMLSKPKELVKRWHA 414
+L +L L+V + + +G + +G + + G EL HW EM + V RWHA
Sbjct: 539 FQLSDVTLILSVYNKRSMKRKEMIGWISLG--LNSSGEEELNHWTEMKESKGQQVCRWHA 596
Query: 415 L 415
L
Sbjct: 597 L 597
>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
Length = 555
Score = 82.8 bits (203), Expect = 5e-16
Identities = 80/301 (26%), Positives = 133/301 (44%), Gaps = 34/301 (11%)
Query: 144 PDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETC--SPLVKLYLLPDERRFLQSKT 201
P+ G L + +Y+ + ++LLV + + + T S V L LLP +++ ++
Sbjct: 257 PEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSI 316
Query: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDC 260
+R P F E F F V S+ I ++F +Y V R +K +++G+ +F L L G
Sbjct: 317 QRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 375
Query: 261 RRVIWRD-----------------------LEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297
+ + +SLE S ++ L YN RL+
Sbjct: 376 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGS-VPEILIGLLYNATTGRLSA 434
Query: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNH--NKFVKCKKTSAVLGSINPVYNETFSFKADA 355
V++ + + +VK++L+N + KCK TS G NPVY ETF F+
Sbjct: 435 EVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK-TSIRRGQPNPVYKETFVFQVAL 493
Query: 356 TELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRG-RELEHWDEMLSKPKELVKRWHA 414
+L +L L+V + + +G + +G + + G EL HW EM + V RWHA
Sbjct: 494 FQLSDVTLILSVYNKRSMKRKEMIGWISLG--LNSSGEEELNHWTEMKESKGQQVCRWHA 551
Query: 415 L 415
L
Sbjct: 552 L 552
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,829,639
Number of Sequences: 37866
Number of extensions: 786753
Number of successful extensions: 2802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 2367
Number of HSP's gapped (non-prelim): 307
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.