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Search of human proteins with 31881667
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
(390 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 793 0.0
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 764 0.0
gi|39752671 synaptotagmin X [Homo sapiens] 150 2e-36
gi|209447073 synaptotagmin I [Homo sapiens] 147 1e-35
gi|5032139 synaptotagmin I [Homo sapiens] 147 1e-35
gi|209447070 synaptotagmin I [Homo sapiens] 147 1e-35
gi|169184624 PREDICTED: similar to synaptotagmin XV-b [Homo sapi... 147 2e-35
gi|28376627 synaptotagmin IX [Homo sapiens] 146 4e-35
gi|238550198 synaptotagmin III [Homo sapiens] 144 1e-34
gi|238550196 synaptotagmin III [Homo sapiens] 144 1e-34
gi|14150054 synaptotagmin III [Homo sapiens] 144 1e-34
gi|211059429 synaptotagmin II [Homo sapiens] 144 2e-34
gi|31543670 synaptotagmin II [Homo sapiens] 144 2e-34
gi|92859638 synaptotagmin V [Homo sapiens] 143 2e-34
gi|45504376 synaptotagmin VI [Homo sapiens] 141 9e-34
gi|38570146 synaptotagmin VII [Homo sapiens] 131 1e-30
gi|40068038 B/K protein [Homo sapiens] 120 3e-27
gi|24308219 synaptotagmin IV [Homo sapiens] 110 2e-24
gi|216548478 synaptotagmin XI [Homo sapiens] 100 4e-21
gi|94536846 synaptotagmin VIII [Homo sapiens] 92 8e-19
gi|29366828 synaptotagmin XII [Homo sapiens] 89 9e-18
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 82 8e-16
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 82 8e-16
gi|6005997 double C2-like domains, beta [Homo sapiens] 79 9e-15
gi|47078261 double C2-like domains, alpha [Homo sapiens] 71 2e-12
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 71 2e-12
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 71 2e-12
gi|24308233 synaptotagmin XIII [Homo sapiens] 69 7e-12
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] 63 4e-10
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] 63 4e-10
>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
Length = 390
Score = 793 bits (2049), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP
Sbjct: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
Query: 61 CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD 120
CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD
Sbjct: 61 CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD 120
Query: 121 ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET 180
ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET
Sbjct: 121 ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET 180
Query: 181 CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK 240
CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK
Sbjct: 181 CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK 240
Query: 241 HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL
Sbjct: 241 HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
Query: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT
Sbjct: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
Query: 361 ASLSLTVVQNMEGDKQATTVELFLFHLTSG 390
ASLSLTVVQNMEGDKQATTVELFLFHLTSG
Sbjct: 361 ASLSLTVVQNMEGDKQATTVELFLFHLTSG 390
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 764 bits (1974), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP
Sbjct: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
Query: 61 CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD 120
CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD
Sbjct: 61 CQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGD 120
Query: 121 ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET 180
ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET
Sbjct: 121 ACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET 180
Query: 181 CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK 240
CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK
Sbjct: 181 CSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRK 240
Query: 241 HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL
Sbjct: 241 HQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
Query: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT
Sbjct: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
Query: 361 ASLSLTVVQNMEGDK 375
ASLSLTVVQNMEGDK
Sbjct: 361 ASLSLTVVQNMEGDK 375
Score = 33.5 bits (75), Expect = 0.34
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 12/119 (10%)
Query: 138 KSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQ--HLQAPSETCSPLVKLYLLPDERR 195
++E+ P G L F + Y RL V +++A+ LQ S VK+ L+ + +
Sbjct: 269 EAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLM-NHNK 327
Query: 196 FLQSKTKRKTS------NPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVL 248
F++ K KTS NP ++E F F+ + + L +V K Q LG+V+
Sbjct: 328 FVKCK---KTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVV 383
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 150 bits (378), Expect = 2e-36
Identities = 92/251 (36%), Positives = 140/251 (55%), Gaps = 9/251 (3%)
Query: 124 VGAINPELYKFPEDKSETDFPDGC--LGRLWFSVEYEQEAERLLVGLIKAQHLQAP--SE 179
+G I PELYK SE + + G+L F+++Y+ E E L+V +IKA L A +
Sbjct: 206 IGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTG 265
Query: 180 TCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQR 239
T P VK+YLLPD ++ Q++ RKT NP FDE F F V+ ++ R L FSVY DR
Sbjct: 266 TSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFS 325
Query: 240 KHQLLGQVLFPLKNETLVGDCRR--VIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297
+H ++G+V+ L N V D R +W+D+ + E + G++ F L Y R+T+
Sbjct: 326 RHDMIGEVI--LDNLFEVSDLSREATVWKDIHCATTE-SIDLGEIMFSLCYLPTAGRMTL 382
Query: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE 357
V++ + L+ + G +VKVSLM + +K +KT+ ++NPVYNE F
Sbjct: 383 TVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPEN 442
Query: 358 LDTASLSLTVV 368
+D SLS+ V+
Sbjct: 443 VDQVSLSIAVM 453
Score = 52.8 bits (125), Expect = 5e-07
Identities = 41/132 (31%), Positives = 67/132 (50%), Gaps = 8/132 (6%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCS--PLVKLYLLPDERRFLQSKT--KR 203
LG + FS+ Y A R+ + +IK ++L+A T S P VK+ L+ + RR + KT K+
Sbjct: 364 LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKK 423
Query: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRV 263
T NP ++E IF + + + Q L +V DR ++++G L E L D
Sbjct: 424 NTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRD---- 479
Query: 264 IWRDLEAESLEP 275
W ++ A +P
Sbjct: 480 HWNEMLAYHRKP 491
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 147 bits (372), Expect = 1e-35
Identities = 89/267 (33%), Positives = 146/267 (54%), Gaps = 14/267 (5%)
Query: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183
+D +ET DG LG+L +S++Y+ + +LLVG+I+A L A T P
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
Query: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
VK++LLPD+++ ++K RKT NP F+E F F+V + + L +VY DR KH +
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303
+G+ P+ N G WRDL++ E + GD+ F L Y +LTVV+L AK
Sbjct: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
Query: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363
L+ + G+ +VK+ LM + K +K KKT+ ++NP YNE+FSF+ ++ +
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
Query: 364 SLTVVQNMEGDKQATTVELFLFHLTSG 390
+TV+ + K ++F+ + ++G
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTG 385
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 147 bits (372), Expect = 1e-35
Identities = 89/267 (33%), Positives = 146/267 (54%), Gaps = 14/267 (5%)
Query: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183
+D +ET DG LG+L +S++Y+ + +LLVG+I+A L A T P
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
Query: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
VK++LLPD+++ ++K RKT NP F+E F F+V + + L +VY DR KH +
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303
+G+ P+ N G WRDL++ E + GD+ F L Y +LTVV+L AK
Sbjct: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
Query: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363
L+ + G+ +VK+ LM + K +K KKT+ ++NP YNE+FSF+ ++ +
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
Query: 364 SLTVVQNMEGDKQATTVELFLFHLTSG 390
+TV+ + K ++F+ + ++G
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTG 385
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 147 bits (372), Expect = 1e-35
Identities = 89/267 (33%), Positives = 146/267 (54%), Gaps = 14/267 (5%)
Query: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183
+D +ET DG LG+L +S++Y+ + +LLVG+I+A L A T P
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
Query: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
VK++LLPD+++ ++K RKT NP F+E F F+V + + L +VY DR KH +
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303
+G+ P+ N G WRDL++ E + GD+ F L Y +LTVV+L AK
Sbjct: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
Query: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363
L+ + G+ +VK+ LM + K +K KKT+ ++NP YNE+FSF+ ++ +
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
Query: 364 SLTVVQNMEGDKQATTVELFLFHLTSG 390
+TV+ + K ++F+ + ++G
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTG 385
>gi|169184624 PREDICTED: similar to synaptotagmin XV-b [Homo
sapiens]
Length = 267
Score = 147 bits (370), Expect = 2e-35
Identities = 71/71 (100%), Positives = 71/71 (100%)
Query: 1 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 60
MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP
Sbjct: 197 MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRP 256
Query: 61 CQPHARTQLSR 71
CQPHARTQLSR
Sbjct: 257 CQPHARTQLSR 267
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 146 bits (368), Expect = 4e-35
Identities = 93/252 (36%), Positives = 135/252 (53%), Gaps = 11/252 (4%)
Query: 124 VGAINPELYK---FPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAP--S 178
+G I PELYK D C G+L F ++Y+ + E+L+V + KA +L A S
Sbjct: 195 IGRIKPELYKQRSLDNDDGRRSNSKAC-GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFS 253
Query: 179 ETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQ 238
T P VK+YLLPD + Q+K RKT NP FDE F+F V + R L FSVY DR
Sbjct: 254 GTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRF 313
Query: 239 RKHQLLGQVLFP--LKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLT 296
+H L+GQV+ L +C ++W+D+E + + G+L F L Y RLT
Sbjct: 314 SRHDLIGQVVVDHFLDLADFPREC--ILWKDIEYVT-NDNVDLGELMFSLCYLPTAGRLT 370
Query: 297 VVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADAT 356
+ +++A+ L+ + G +VKVSLM + +K +KTS ++NPVYNE F
Sbjct: 371 ITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPE 430
Query: 357 ELDTASLSLTVV 368
+D LS+ V+
Sbjct: 431 NIDQIHLSIAVM 442
Score = 58.9 bits (141), Expect = 7e-09
Identities = 39/102 (38%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKT--KR 203
LG L FS+ Y A RL + +IKA++L+A T P VK+ L+ D RR + KT KR
Sbjct: 353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKR 412
Query: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLG 245
T NP ++E +F V + I Q L +V DR ++++G
Sbjct: 413 NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIG 454
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 144 bits (363), Expect = 1e-34
Identities = 96/281 (34%), Positives = 141/281 (50%), Gaps = 16/281 (5%)
Query: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149
P P+SE LP GG A ++G I PELY+ P + P G
Sbjct: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
Query: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207
R+ F++ Y +++L+V +++A L A P VK+YLLPD ++ Q+K RKT N
Sbjct: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
Query: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267
P F+E F F V + QR L FSVY DR +H L+GQV+ E R +WRD
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
Query: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327
+ E ++ G+L F L Y RLTV +++A L+ + G +VK SL++ +
Sbjct: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
Query: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368
+K +KTS ++NP YNE F ++ LS+ VV
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 144 bits (363), Expect = 1e-34
Identities = 96/281 (34%), Positives = 141/281 (50%), Gaps = 16/281 (5%)
Query: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149
P P+SE LP GG A ++G I PELY+ P + P G
Sbjct: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
Query: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207
R+ F++ Y +++L+V +++A L A P VK+YLLPD ++ Q+K RKT N
Sbjct: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
Query: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267
P F+E F F V + QR L FSVY DR +H L+GQV+ E R +WRD
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
Query: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327
+ E ++ G+L F L Y RLTV +++A L+ + G +VK SL++ +
Sbjct: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
Query: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368
+K +KTS ++NP YNE F ++ LS+ VV
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 144 bits (363), Expect = 1e-34
Identities = 96/281 (34%), Positives = 141/281 (50%), Gaps = 16/281 (5%)
Query: 103 PCPASE----LLPHTSSGGLGDACMVGAINPELYKF--PEDKSETDFPDGC-------LG 149
P P+SE LP GG A ++G I PELY+ P + P G
Sbjct: 242 PDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCG 301
Query: 150 RLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKTKRKTSN 207
R+ F++ Y +++L+V +++A L A P VK+YLLPD ++ Q+K RKT N
Sbjct: 302 RISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLN 361
Query: 208 PQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRD 267
P F+E F F V + QR L FSVY DR +H L+GQV+ E R +WRD
Sbjct: 362 PVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRD 421
Query: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNK 327
+ E ++ G+L F L Y RLTV +++A L+ + G +VK SL++ +
Sbjct: 422 I-VEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR 480
Query: 328 FVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368
+K +KTS ++NP YNE F ++ LS+ VV
Sbjct: 481 RLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVV 521
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 144 bits (362), Expect = 2e-34
Identities = 82/251 (32%), Positives = 138/251 (54%), Gaps = 4/251 (1%)
Query: 136 EDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSPLVKLYLLPDE 193
E + E + LG+L FS++Y+ +A +L VG+++A L A T P VK++LLPD+
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
Query: 194 RRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253
++ ++K RKT NP F+E F F+V + + + L ++Y DR KH ++G+V P+
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
Query: 254 ETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGI 313
L WRDL+ E P + GD+ L Y +LTV +L AK L+ + G+
Sbjct: 248 VDLGQPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
Query: 314 VSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEG 373
+VK+ LM + K +K KKT+ ++NP +NE+FSF+ ++ + +TV+ +
Sbjct: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
Query: 374 DKQATTVELFL 384
K ++F+
Sbjct: 366 GKNEAIGKIFV 376
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 144 bits (362), Expect = 2e-34
Identities = 82/251 (32%), Positives = 138/251 (54%), Gaps = 4/251 (1%)
Query: 136 EDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSPLVKLYLLPDE 193
E + E + LG+L FS++Y+ +A +L VG+++A L A T P VK++LLPD+
Sbjct: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
Query: 194 RRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253
++ ++K RKT NP F+E F F+V + + + L ++Y DR KH ++G+V P+
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
Query: 254 ETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGI 313
L WRDL+ E P + GD+ L Y +LTV +L AK L+ + G+
Sbjct: 248 VDLGQPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
Query: 314 VSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEG 373
+VK+ LM + K +K KKT+ ++NP +NE+FSF+ ++ + +TV+ +
Sbjct: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
Query: 374 DKQATTVELFL 384
K ++F+
Sbjct: 366 GKNEAIGKIFV 376
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 143 bits (361), Expect = 2e-34
Identities = 82/223 (36%), Positives = 129/223 (57%), Gaps = 4/223 (1%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPS--ETCSPLVKLYLLPDERRFLQSKTKRKT 205
LGRL +S++Y+ ++ +LLVG+++A L A + P V++YLLPD+RR ++K R+T
Sbjct: 109 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT 168
Query: 206 SNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIW 265
NP F E F F+V + RVL +VY DR ++ +G+V P+ + L + W
Sbjct: 169 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQA--W 226
Query: 266 RDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325
R+L+A E + GD+ F L Y +LTV+VL AK L+ + G+ +VKV L+
Sbjct: 227 RELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQG 286
Query: 326 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368
K V+ KKT+ ++NP YNE FSF+ ++ + LTV+
Sbjct: 287 GKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVL 329
Score = 49.3 bits (116), Expect = 6e-06
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 14/158 (8%)
Query: 130 ELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSE--TCSPLVKL 187
EL P ++ E LG + FS+ Y A +L V +++A++L+ P VK+
Sbjct: 228 ELQAAPREEQEK------LGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKV 281
Query: 188 YLLPDERRFLQSKT--KRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLG 245
+LL ++ + KT K+ T NP ++E F F+V + + ++ +V D+ K++ +G
Sbjct: 282 HLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIG 341
Query: 246 QVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQ 283
+V G W D+ A P +++ L+
Sbjct: 342 RVAV----GAAAGGAGLRHWADMLANPRRPIAQWHSLR 375
Score = 42.7 bits (99), Expect = 6e-04
Identities = 35/110 (31%), Positives = 52/110 (47%), Gaps = 13/110 (11%)
Query: 269 EAESLEP-PS----------EFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVF 317
E E LEP PS E G LQ+ L Y+ +L V +L+A GL + G +
Sbjct: 88 EVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPY 147
Query: 318 VKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTV 367
V+V L+ + + +T ++NP + ETF+FK EL L + V
Sbjct: 148 VRVYLLPDKR--RRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAV 195
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 141 bits (356), Expect = 9e-34
Identities = 88/252 (34%), Positives = 139/252 (55%), Gaps = 11/252 (4%)
Query: 124 VGAINPELYKFPE---DKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPS-- 178
+G I PELYK + ++++ C G++ FS+ Y+ E E L+V ++KA L A
Sbjct: 119 IGRIKPELYKQKSVDGEDAKSEATKSC-GKINFSLRYDYETETLIVRILKAFDLPAKDFC 177
Query: 179 ETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQ 238
+ P VK+YLLPD + LQ++ RKT NP FDE+F F V + + R L SV+ DR
Sbjct: 178 GSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRF 237
Query: 239 RKHQLLGQVLFPLKNETLVGDCRR--VIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLT 296
+H ++G+V+ L N D R IW+D++ + E + G++ F L Y RLT
Sbjct: 238 SRHDMIGEVI--LDNLFEASDLSRETSIWKDIQYATSE-SVDLGEIMFSLCYLPTAGRLT 294
Query: 297 VVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADAT 356
+ V++ + L+ + G +VKVSL+ + +K KKT+ ++NPVYNE F
Sbjct: 295 LTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPE 354
Query: 357 ELDTASLSLTVV 368
+D SL ++V+
Sbjct: 355 NMDQVSLLISVM 366
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 131 bits (329), Expect = 1e-30
Identities = 85/260 (32%), Positives = 139/260 (53%), Gaps = 13/260 (5%)
Query: 123 MVGAINPELYKFPEDKSETDFPDGC----LGRLWFSVEYEQEAERLLVGLIKAQHLQAP- 177
+V ++ E+ E + +GC LGR+ FSV Y + L V ++KAQ L A
Sbjct: 107 LVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKD 166
Query: 178 -SETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHV 235
S T P VK+YLLPD++ L++K KRK NP ++E F+F+ + + QR+L V
Sbjct: 167 FSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDY 226
Query: 236 DRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRL 295
DR ++ +G+V PL L + W+DL+ S + G+L L YN + +
Sbjct: 227 DRFSRNDPIGEVSIPLNKVDLTQ--MQTFWKDLKPCS-DGSGSRGELLLSLCYNPSANSI 283
Query: 296 TVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADA 355
V +++A+ L+ + G +VKV LM +K V+ KKT + ++NP++NE+F+F
Sbjct: 284 IVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPT 343
Query: 356 TELDTASLSLTVVQNMEGDK 375
+L ++ +TV M+ DK
Sbjct: 344 EKLRETTIIITV---MDKDK 360
Score = 58.9 bits (141), Expect = 7e-09
Identities = 38/158 (24%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Query: 130 ELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPS--ETCSPLVKL 187
++ F +D G G L S+ Y A ++V +IKA++L+A T P VK+
Sbjct: 249 QMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKV 308
Query: 188 YLLPDERRFLQSKT--KRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLG 245
+L+ ++R + KT ++ NP F+E F F + ++ + + + +V D+ ++ ++G
Sbjct: 309 WLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIG 368
Query: 246 QVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQ 283
++ K+ G+ + W+D+ A +P +++ L+
Sbjct: 369 KIYLSWKSGP--GEVKH--WKDMIARPRQPVAQWHQLK 402
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 120 bits (300), Expect = 3e-27
Identities = 82/229 (35%), Positives = 116/229 (50%), Gaps = 12/229 (5%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET---------CSPLVKLYLLPDERRFLQ 198
LG L FS +Y+ L V +I+A+ L P +P VK+ LLPD++ Q
Sbjct: 185 LGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQ 244
Query: 199 SKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVG 258
+ KRKT P F+E + F++ +R L +V D+ +H ++G+V PL LV
Sbjct: 245 TGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVK 304
Query: 259 DCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFV 318
W S + E G+L L+Y RL V V+RAK L + FV
Sbjct: 305 GGH---WWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFV 361
Query: 319 KVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTV 367
K+ L++ K VK KKTS + G+I+P YNE+FSFK EL+ ASL TV
Sbjct: 362 KIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTV 410
Score = 42.4 bits (98), Expect = 7e-04
Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAP--SETCSPLVKLYLLPDERRFLQSKTK--R 203
LG L S+ Y A RL V +I+A+ L S+ P VK+ L+ + KT R
Sbjct: 322 LGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLR 381
Query: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVL 248
T +P ++E F F+V + + L F+V+ + + + +G+++
Sbjct: 382 GTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIV 426
Score = 34.3 bits (77), Expect = 0.20
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 9/108 (8%)
Query: 268 LEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLR-------LQEDRGIVSVFVKV 320
L E + + G L F Y+ + LTV V+ A+ L ++D + +VK+
Sbjct: 174 LTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKI 233
Query: 321 SLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368
L+ K K+T + PV+ E ++F+ E +L LTVV
Sbjct: 234 CLLPDQK--NSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVV 279
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 110 bits (276), Expect = 2e-24
Identities = 73/241 (30%), Positives = 125/241 (51%), Gaps = 5/241 (2%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSE---TCSPLVKLYLLPDERRFLQSKTKRK 204
LG L+FS+EY E + +V + +A+ L A E T P +K+ +LP+++ ++++ RK
Sbjct: 154 LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRK 213
Query: 205 TSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRV 263
T +P FDE F F + I + L F++ DR + ++G+VL PL L + + +
Sbjct: 214 TLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIEL-SEGKML 272
Query: 264 IWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLM 323
+ R++ ++ S G+L L Y + LTVVVL+A+ L + G+ +VKV+L
Sbjct: 273 MNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLY 332
Query: 324 NHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKQATTVELF 383
+ K + KKT + N V+NE F F L+ S+ V+ + G + +L
Sbjct: 333 HAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLV 392
Query: 384 L 384
L
Sbjct: 393 L 393
Score = 46.6 bits (109), Expect = 4e-05
Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 4/115 (3%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAP--SETCSPLVKLYLLPDERRFLQSKT--KRK 204
G L S+ Y+ L V ++KA+HL S P VK+ L ++R + KT K+
Sbjct: 289 GELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKC 348
Query: 205 TSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGD 259
T N F+E F+F + + + ++F V +R +++++GQ++ E G+
Sbjct: 349 TPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGE 403
Score = 37.4 bits (85), Expect = 0.023
Identities = 25/99 (25%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
Query: 272 SLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVS-VFVKVSLMNHNKFVK 330
S E + G L F L YN V + A+GL +++ + S ++K++++ K
Sbjct: 147 SEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHK- 205
Query: 331 CKKTSAVLGSINPVYNETFSFKA-DATELDTASLSLTVV 368
KT + +++P ++ETF+F T++ +L T++
Sbjct: 206 -VKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTIL 243
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 99.8 bits (247), Expect = 4e-21
Identities = 70/230 (30%), Positives = 119/230 (51%), Gaps = 8/230 (3%)
Query: 145 DGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA---PSETCSPLVKLYLLPDERRFLQSKT 201
D LG L FSV+Y + L+V + +A L ++ P +K+ +LPD+R ++++
Sbjct: 155 DVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRV 214
Query: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN-ETLVGD 259
RKT +P FDE F F + + VL F V DR + ++G+V+ PL + G
Sbjct: 215 LRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGK 274
Query: 260 CRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIV-SVFV 318
+ + RD+ +++ G+LQ LSY R+TVVVL+A+ L + G+ + +V
Sbjct: 275 VQ--LTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYV 332
Query: 319 KVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368
KV++ K + KKT ++NP++NE+F + L S+ V+
Sbjct: 333 KVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVI 382
Score = 55.5 bits (132), Expect = 8e-08
Identities = 38/139 (27%), Positives = 72/139 (51%), Gaps = 8/139 (5%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSETC---SPLVKLYLLPDERRFLQSKT--KR 203
G L S+ Y+ A+R+ V ++KA+HL T +P VK+ + +R + KT K+
Sbjct: 293 GELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKK 352
Query: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRV 263
T NP F+E FI+ + + + ++F V DR K++++G+++ + T G
Sbjct: 353 CTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASG---AE 409
Query: 264 IWRDLEAESLEPPSEFGDL 282
WR++ +P +++ L
Sbjct: 410 HWREVCESPRKPVAKWHSL 428
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 92.0 bits (227), Expect = 8e-19
Identities = 67/221 (30%), Positives = 107/221 (48%), Gaps = 11/221 (4%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKTKRKTSNP 208
GRL S+E++ ++ + VGL +A L+ P T P ++ + ++K R T P
Sbjct: 119 GRLQLSLEFDFGSQEIRVGLRQAADLR-PGGTVDPYARVSVSTQAGHRHETKVHRGTLCP 177
Query: 209 QFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVI--WR 266
FDE F + + L+ +++ R H+ LG++ PL D + V+ W
Sbjct: 178 VFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV----DLQHVLEHWY 233
Query: 267 DLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHN 326
L + P + G+L F L Y RLTVVVL A+GLR G+ +VKV LM +
Sbjct: 234 LLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLR----PGLAEPYVKVQLMLNQ 289
Query: 327 KFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTV 367
+ K +KT+ G+ P +NE F+F +++ L L V
Sbjct: 290 RKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAV 330
Score = 40.0 bits (92), Expect = 0.004
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 4/102 (3%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKT--KRKT 205
+G L FS+ Y + RL V +++A+ L+ P VK+ L+ ++R++ + KT K+ T
Sbjct: 246 VGELCFSLRYVPSSGRLTVVVLEARGLRPG--LAEPYVKVQLMLNQRKWKKRKTATKKGT 303
Query: 206 SNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQV 247
+ P F+E F F V + L +V+ + + +G+V
Sbjct: 304 AAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKV 345
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 88.6 bits (218), Expect = 9e-18
Identities = 70/241 (29%), Positives = 116/241 (48%), Gaps = 18/241 (7%)
Query: 139 SETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHL----QAPSETCSPLVKLYLLPDER 194
S T D LG++ S+EY+ + L V +++ + L +A E+C +++ LLPDE+
Sbjct: 144 SNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESC--FMRVSLLPDEQ 201
Query: 195 RFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQV-----LF 249
S+ +R + FDE F + + ++ L+FSV+ +D ++ G V +
Sbjct: 202 IVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVL 261
Query: 250 PLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQE 309
L + G W L+ ++ + G++ LSY RLTVVV++AK L
Sbjct: 262 DLPLQPFSG------WLYLQDQN-KAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTN 314
Query: 310 DRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQ 369
D+ FVKV L+ + + KKT+ NPV+NE F A L SL +TV +
Sbjct: 315 DKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAE 374
Query: 370 N 370
+
Sbjct: 375 S 375
Score = 53.1 bits (126), Expect = 4e-07
Identities = 35/105 (33%), Positives = 55/105 (52%), Gaps = 4/105 (3%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSE--TCSPLVKLYLLPDERRFLQSKT--KR 203
+G + S+ Y AERL V ++KA++L ++ T P VK+YLL D R+ + KT KR
Sbjct: 284 VGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKR 343
Query: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVL 248
NP F+E IF V + + L+ +V + +G V+
Sbjct: 344 DDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVI 388
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 82.0 bits (201), Expect = 8e-16
Identities = 71/244 (29%), Positives = 106/244 (43%), Gaps = 25/244 (10%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSET---CSPLVKLYLLPDERRFLQSKT--KR 203
GR+ FS++YEQ+ + L+V + + L E +P VK YLLPD+ R + KT KR
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPL---KNETLVGDC 260
T NP +DE +++ + QR L+FSV+H R ++ LG+ + K + + C
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 261 RRVIWRDLEAESLEPPSEFGDLQFCLSY----------------NDYLSRLTVVVLRAKG 304
+ + PS G+L L Y L V + AK
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 305 LRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE-LDTASL 363
L + G FVK L+ +KT + ++NP YN TF + E L L
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 364 SLTV 367
LTV
Sbjct: 598 ELTV 601
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 82.0 bits (201), Expect = 8e-16
Identities = 71/244 (29%), Positives = 106/244 (43%), Gaps = 25/244 (10%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSET---CSPLVKLYLLPDERRFLQSKT--KR 203
GR+ FS++YEQ+ + L+V + + L E +P VK YLLPD+ R + KT KR
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPL---KNETLVGDC 260
T NP +DE +++ + QR L+FSV+H R ++ LG+ + K + + C
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 261 RRVIWRDLEAESLEPPSEFGDLQFCLSY----------------NDYLSRLTVVVLRAKG 304
+ + PS G+L L Y L V + AK
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 305 LRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE-LDTASL 363
L + G FVK L+ +KT + ++NP YN TF + E L L
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 364 SLTV 367
LTV
Sbjct: 598 ELTV 601
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 78.6 bits (192), Expect = 9e-15
Identities = 72/250 (28%), Positives = 116/250 (46%), Gaps = 17/250 (6%)
Query: 133 KFPEDKSETDF--PDGC--LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVK 186
K PED+ + D D C LG L FS+ Y+QE L + KA+ L+ P VK
Sbjct: 108 KPPEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVK 167
Query: 187 LYLLPDERRF--LQSKTKRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQL 243
L+LLP + L++KT R T NP ++E + ++ + + ++ L+ SV D+ R ++
Sbjct: 168 LHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEF 227
Query: 244 LGQVLFPLK----NETLVGDCRRVIWRDLEAESLEPPS--EFGDLQFCLSYNDYLSRLTV 297
+G+ PLK N T + + + L + E S E G + L Y+ L V
Sbjct: 228 IGETRVPLKKLKPNHTKTFNI--CLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLV 285
Query: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATE 357
++R L + G +VK L KT+ ++NP +NE F ++ +
Sbjct: 286 GIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGD 345
Query: 358 LDTASLSLTV 367
L SL +TV
Sbjct: 346 LAKKSLEVTV 355
Score = 63.5 bits (153), Expect = 3e-10
Identities = 37/120 (30%), Positives = 66/120 (55%), Gaps = 5/120 (4%)
Query: 133 KFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLL 190
+ P DK+E + GR+ S++Y + + LLVG+++ HL A P VK YL
Sbjct: 253 QLPVDKTEDKSLEE-RGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLR 311
Query: 191 PDERRFLQSKT--KRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVL 248
PD + + KT K+KT NP+F+E F +++ + ++ L+ +V+ D + + +G V+
Sbjct: 312 PDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVV 371
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 70.9 bits (172), Expect = 2e-12
Identities = 68/268 (25%), Positives = 116/268 (43%), Gaps = 35/268 (13%)
Query: 135 PEDKSETDFPDG----CLGRLWFSVEYEQEAERLLVGLIKAQHLQAP--SETCSPLVKLY 188
PED +E D D LG L F + Y++ + L +++A+ L+ + P VKL+
Sbjct: 73 PEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLH 132
Query: 189 LLPD--ERRFLQSKTKRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLG 245
LLP + L++KT+R T NP ++E + ++ IT +VL+ +V D+ ++ +G
Sbjct: 133 LLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIG 192
Query: 246 QVLFPLKN----------------------ETLVGDCRRVIWRDLEAESLEPP----SEF 279
++ PL+ ++ R + E E E E
Sbjct: 193 EIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEER 252
Query: 280 GDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLG 339
G + LSY+ L V +LR L + G +VK L KT
Sbjct: 253 GRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKK 312
Query: 340 SINPVYNETFSFKADATELDTASLSLTV 367
++NP +NE F ++ + + L T +L +TV
Sbjct: 313 TLNPEFNEEFFYEIELSTLATKTLEVTV 340
Score = 62.8 bits (151), Expect = 5e-10
Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 4/103 (3%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKT--KRK 204
GR+ S+ Y LLVG+++ HL A P VK YL PD + + KT K+K
Sbjct: 253 GRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKK 312
Query: 205 TSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQV 247
T NP+F+E F +++ T+ + L+ +V+ D + + +G V
Sbjct: 313 TLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGV 355
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 70.9 bits (172), Expect = 2e-12
Identities = 62/247 (25%), Positives = 109/247 (44%), Gaps = 27/247 (10%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRF--LQSKTKR 203
LG L FS+ Y+Q+ L +IKA+ L+ P VKL+LLP + L++KT R
Sbjct: 393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLR 452
Query: 204 KTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLF------------- 249
T NP ++E ++ ++ + + ++ L+ SV D+ ++ +G+ F
Sbjct: 453 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 512
Query: 250 --------PLKNETLVGDCRRV-IWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
P+K G R + ++ + + E + E G + L Y+ L V ++
Sbjct: 513 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGII 572
Query: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
R L + G FVK+ L KT ++NP +NE F + ++L
Sbjct: 573 RCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAK 632
Query: 361 ASLSLTV 367
SL ++V
Sbjct: 633 KSLDISV 639
Score = 57.8 bits (138), Expect = 2e-08
Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKT--KRK 204
G++ S+ Y + L+VG+I+ HL A P VKL+L PD + + KT K+K
Sbjct: 552 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKK 611
Query: 205 TSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLG 245
T NP+F+E F + + + ++ L SV+ D + + +G
Sbjct: 612 TLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 652
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 70.9 bits (172), Expect = 2e-12
Identities = 62/247 (25%), Positives = 109/247 (44%), Gaps = 27/247 (10%)
Query: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRF--LQSKTKR 203
LG L FS+ Y+Q+ L +IKA+ L+ P VKL+LLP + L++KT R
Sbjct: 389 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLR 448
Query: 204 KTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLF------------- 249
T NP ++E ++ ++ + + ++ L+ SV D+ ++ +G+ F
Sbjct: 449 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 508
Query: 250 --------PLKNETLVGDCRRV-IWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVL 300
P+K G R + ++ + + E + E G + L Y+ L V ++
Sbjct: 509 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGII 568
Query: 301 RAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDT 360
R L + G FVK+ L KT ++NP +NE F + ++L
Sbjct: 569 RCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAK 628
Query: 361 ASLSLTV 367
SL ++V
Sbjct: 629 KSLDISV 635
Score = 57.8 bits (138), Expect = 2e-08
Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
Query: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSET--CSPLVKLYLLPDERRFLQSKT--KRK 204
G++ S+ Y + L+VG+I+ HL A P VKL+L PD + + KT K+K
Sbjct: 548 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKK 607
Query: 205 TSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLG 245
T NP+F+E F + + + ++ L SV+ D + + +G
Sbjct: 608 TLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 648
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 68.9 bits (167), Expect = 7e-12
Identities = 84/390 (21%), Positives = 161/390 (41%), Gaps = 46/390 (11%)
Query: 7 LVIGGTIGGLLLLLLIGASCCLWRRFC---ATLTYEELPGTPAMATTAASSGQR------ 57
+ +G T+G +L + CL R L ++ P + S Q+
Sbjct: 8 IALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDQDPDLEKAKPSLLGSAQQFNVKKS 67
Query: 58 DRPCQPHARTQLSR--PPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPAS-------- 107
P QP A + P P + D+ L S E AP P P +
Sbjct: 68 TEPVQPRALLKFPDIYGPRPAVTAPEVINYADY-SLRSTEEPTAPASPQPPNDSRLKRQV 126
Query: 108 --ELLPHTSSGGLGDACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLL 165
EL +G + D C++ NPE + S P +L + ++Y+ + L
Sbjct: 127 TEELFILPQNGVVEDVCVMETWNPE-----KAASWNQAP-----KLHYCLDYDCQKAELF 176
Query: 166 VGLIKAQHLQAPSETCSPLVKLYL---LPDERRFLQSKT--KRKTSNPQFDEHFIFQVSS 220
V L+A + Y+ + + ++++T K++ + ++E + ++
Sbjct: 177 V-----TRLEAVTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEEGLVLPLAE 231
Query: 221 KTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFG 280
+ + L ++ DR +H + G++ L ++ + W +L+ + EP + G
Sbjct: 232 EELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQ--WGELKTSAKEPSAGAG 289
Query: 281 DLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIV--SVFVKVSLMNHNKFVKCKKTSAVL 338
++ +SY +RL VV+++AK L + + ++ V VKV+L + + +K K+T
Sbjct: 290 EVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKLKKKQTKRAK 349
Query: 339 GSINPVYNETFSFKADATELDTASLSLTVV 368
INPV+NE F+ L +S+ L V+
Sbjct: 350 HKINPVWNEMIMFELPDDLLQASSVELEVL 379
Score = 35.0 bits (79), Expect = 0.12
Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 6/116 (5%)
Query: 136 EDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSET----CSPLVKLYLLP 191
E K+ P G + S+ Y A RLLV LIKA++L + VK+ L
Sbjct: 276 ELKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKH 335
Query: 192 DERRFLQSKTKRKTS--NPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLG 245
R+ + +TKR NP ++E +F++ + ++ V D + LG
Sbjct: 336 QARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALG 391
>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 63.2 bits (152), Expect = 4e-10
Identities = 65/240 (27%), Positives = 96/240 (40%), Gaps = 52/240 (21%)
Query: 185 VKLYLLPDERRFLQSKTKRKT-SNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
VK YLLPD+ R + KTK +T +NP+F+E + +S + R L+ SV+H DR ++
Sbjct: 447 VKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSF 506
Query: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEF---------GDLQFCLSY------ 288
LG+V P + E L+P EF G+L L Y
Sbjct: 507 LGEVEIPFDSWNFENPTD-------EWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEEN 559
Query: 289 ----------NDYLSR-------------LTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325
N + L V + AK L + G FVK L+
Sbjct: 560 LMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPD 619
Query: 326 NKFVKCKKTSAVLGSINPVYNETFSFKA-DATELDTASLSLTVVQNMEGDKQATTVELFL 384
+ KT + S+NP +N TF F ++ L LT+ DK+A + +FL
Sbjct: 620 DSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTI-----WDKEAFSSNIFL 674
Score = 35.8 bits (81), Expect = 0.068
Identities = 38/157 (24%), Positives = 72/157 (45%), Gaps = 12/157 (7%)
Query: 125 GAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIK-----AQHLQAPSE 179
G + L P +++ P+ G F ++E+ + G+++ A++L A
Sbjct: 545 GELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKS 604
Query: 180 --TCSPLVKLYLLPDERRFLQSKTK--RKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYH 234
T VK YLLPD+ + + KT +K+ NPQ++ F+F + + I L+ +++
Sbjct: 605 GGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWD 664
Query: 235 VDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAE 271
+ + LG V L + + V + V W D + E
Sbjct: 665 KEAFSSNIFLGGV--RLNSGSGVSHGKNVDWMDSQGE 699
Score = 32.7 bits (73), Expect = 0.58
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 280 GDLQFCLSYNDYLSRLTVVVLRAKGLRL-QEDRGIVSVFVKVSLMNHNKFVKCKKTSAVL 338
G++ +SY L + V + L + E + +VK L+ +KT
Sbjct: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467
Query: 339 GSINPVYNETFSFKADATELDTASLSLTV 367
G+ NP +NET + T+L+T +L L+V
Sbjct: 468 GT-NPEFNETLKYTISHTQLETRTLQLSV 495
>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
Length = 752
Score = 63.2 bits (152), Expect = 4e-10
Identities = 65/240 (27%), Positives = 96/240 (40%), Gaps = 52/240 (21%)
Query: 185 VKLYLLPDERRFLQSKTKRKT-SNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
VK YLLPD+ R + KTK +T +NP+F+E + +S + R L+ SV+H DR ++
Sbjct: 469 VKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSF 528
Query: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEF---------GDLQFCLSY------ 288
LG+V P + E L+P EF G+L L Y
Sbjct: 529 LGEVEIPFDSWNFENPTD-------EWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEEN 581
Query: 289 ----------NDYLSR-------------LTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325
N + L V + AK L + G FVK L+
Sbjct: 582 LMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPD 641
Query: 326 NKFVKCKKTSAVLGSINPVYNETFSFKA-DATELDTASLSLTVVQNMEGDKQATTVELFL 384
+ KT + S+NP +N TF F ++ L LT+ DK+A + +FL
Sbjct: 642 DSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTI-----WDKEAFSSNIFL 696
Score = 35.8 bits (81), Expect = 0.068
Identities = 38/157 (24%), Positives = 72/157 (45%), Gaps = 12/157 (7%)
Query: 125 GAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIK-----AQHLQAPSE 179
G + L P +++ P+ G F ++E+ + G+++ A++L A
Sbjct: 567 GELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKS 626
Query: 180 --TCSPLVKLYLLPDERRFLQSKTK--RKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYH 234
T VK YLLPD+ + + KT +K+ NPQ++ F+F + + I L+ +++
Sbjct: 627 GGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWD 686
Query: 235 VDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAE 271
+ + LG V L + + V + V W D + E
Sbjct: 687 KEAFSSNIFLGGV--RLNSGSGVSHGKNVDWMDSQGE 721
Score = 32.7 bits (73), Expect = 0.58
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 280 GDLQFCLSYNDYLSRLTVVVLRAKGLRL-QEDRGIVSVFVKVSLMNHNKFVKCKKTSAVL 338
G++ +SY L + V + L + E + +VK L+ +KT
Sbjct: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489
Query: 339 GSINPVYNETFSFKADATELDTASLSLTV 367
G+ NP +NET + T+L+T +L L+V
Sbjct: 490 GT-NPEFNETLKYTISHTQLETRTLQLSV 517
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,242,786
Number of Sequences: 37866
Number of extensions: 720243
Number of successful extensions: 2619
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 2220
Number of HSP's gapped (non-prelim): 308
length of query: 390
length of database: 18,247,518
effective HSP length: 104
effective length of query: 286
effective length of database: 14,309,454
effective search space: 4092503844
effective search space used: 4092503844
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.