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Search of human proteins with 31317256
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31317256 X-linked neuroligin 4 [Homo sapiens]
(816 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 1696 0.0
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 1696 0.0
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 1656 0.0
gi|51593088 neuroligin 3 [Homo sapiens] 1231 0.0
gi|7662470 neuroligin 1 [Homo sapiens] 1221 0.0
gi|30840978 neuroligin 2 [Homo sapiens] 1033 0.0
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 323 3e-88
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 320 3e-87
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 319 6e-87
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 294 2e-79
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 293 6e-79
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 291 1e-78
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 291 2e-78
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 288 2e-77
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 283 5e-76
gi|33563374 carboxylesterase 3 [Homo sapiens] 283 5e-76
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 280 3e-75
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 239 7e-63
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 231 3e-60
gi|55770862 thyroglobulin [Homo sapiens] 193 6e-49
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 155 1e-37
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 155 1e-37
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 92 2e-18
gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransfer... 34 0.48
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 33 0.82
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 33 0.82
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 33 0.82
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 33 0.82
gi|10937869 survival of motor neuron 2, centromeric isoform d [H... 32 1.8
gi|4507091 survival of motor neuron 1, telomeric isoform d [Homo... 32 1.8
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1696 bits (4392), Expect = 0.0
Identities = 816/816 (100%), Positives = 816/816 (100%)
Query: 1 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT 60
MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT
Sbjct: 1 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT 60
Query: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL 120
PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL
Sbjct: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL 120
Query: 121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG 180
HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG
Sbjct: 121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG 180
Query: 181 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA
Sbjct: 181 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
Query: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL
Sbjct: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
Query: 301 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG
Sbjct: 301 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
Query: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI
Sbjct: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
Query: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM
Sbjct: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
Query: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV
Sbjct: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
Query: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL
Sbjct: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
Query: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED
Sbjct: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
Query: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTND 720
TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTND
Sbjct: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTND 720
Query: 721 IAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTIT 780
IAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTIT
Sbjct: 721 IAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTIT 780
Query: 781 MIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
MIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV
Sbjct: 781 MIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1696 bits (4392), Expect = 0.0
Identities = 816/816 (100%), Positives = 816/816 (100%)
Query: 1 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT 60
MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT
Sbjct: 1 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT 60
Query: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL 120
PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL
Sbjct: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL 120
Query: 121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG 180
HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG
Sbjct: 121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG 180
Query: 181 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA
Sbjct: 181 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
Query: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL
Sbjct: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
Query: 301 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG
Sbjct: 301 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
Query: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI
Sbjct: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
Query: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM
Sbjct: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
Query: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV
Sbjct: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
Query: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL
Sbjct: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
Query: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED
Sbjct: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
Query: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTND 720
TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTND
Sbjct: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTND 720
Query: 721 IAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTIT 780
IAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTIT
Sbjct: 721 IAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTIT 780
Query: 781 MIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
MIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV
Sbjct: 781 MIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 1656 bits (4289), Expect = 0.0
Identities = 796/816 (97%), Positives = 803/816 (98%)
Query: 1 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT 60
M RPQGLLWLPLLFT VCVMLNSNVLLW+TALAIKFTLIDSQAQYPVVNTNYGKI+GLRT
Sbjct: 1 MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRT 60
Query: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL 120
PLP+EILGPVEQYLGVPYASPPTGERRFQPPE PSSWTGIRN TQF+AVCPQHLDER LL
Sbjct: 61 PLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLL 120
Query: 121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG 180
HDMLPIWFT +LDTLMTYVQDQNEDCLYLNIYVP EDDIH+QNSKKPVMVYIHGGSYMEG
Sbjct: 121 HDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG 180
Query: 181 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
TGNMIDGSILASYGNVIVITIN RLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA
Sbjct: 181 TGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA 240
Query: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL
Sbjct: 241 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL 300
Query: 301 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
ADKVGCNMLDTTDMVECL+NKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG
Sbjct: 301 ADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG 360
Query: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI
Sbjct: 361 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI 420
Query: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM
Sbjct: 421 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM 480
Query: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV
Sbjct: 481 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 540
Query: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL
Sbjct: 541 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 600
Query: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED
Sbjct: 601 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED 660
Query: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTND 720
TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHR PSPQRNTTND
Sbjct: 661 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTND 720
Query: 721 IAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTIT 780
I HIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIP MTPNTIT
Sbjct: 721 ITHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTIT 780
Query: 781 MIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
MIPNTL GMQPLHTF TFSGGQNSTNLPHGHSTTRV
Sbjct: 781 MIPNTLMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV 816
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 1231 bits (3186), Expect = 0.0
Identities = 594/811 (73%), Positives = 680/811 (83%), Gaps = 29/811 (3%)
Query: 27 LWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGER 86
LW +LA++ + +QA P VNT++GK+RG R PLP+EILGPV+QYLGVPYA+PP GE+
Sbjct: 26 LWFLSLALRAS---TQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEK 82
Query: 87 RFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDC 146
RF PPEPP SW+GIRN T F VCPQ++ ++ MLP+WFTANLD + TY+Q+ NEDC
Sbjct: 83 RFLPPEPPPSWSGIRNATHFPPVCPQNI-HTAVPEVMLPVWFTANLDIVATYIQEPNEDC 141
Query: 147 LYLNIYVPTED--------------------DIHDQNSKKPVMVYIHGGSYMEGTGNMID 186
LYLN+YVPTED DI D +K PVMVYIHGGSYMEGTGNMID
Sbjct: 142 LYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAK-PVMVYIHGGSYMEGTGNMID 200
Query: 187 GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246
GSILASYGNVIVIT+NYR+G+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+
Sbjct: 201 GSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPR 260
Query: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGC 306
R+T+FGSG GASCVSLLTLSH+SEGLFQ+AIIQSG+ALSSWAVNYQP KYT +LADKVGC
Sbjct: 261 RITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGC 320
Query: 307 NMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYD 366
N+LDT DMV+CLR K+ KEL++Q I PA YH+AFGPVIDGDVIPDDP+ILMEQGEFLNYD
Sbjct: 321 NVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYD 380
Query: 367 IMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTD 426
IMLGVNQGEGLKFV+G+VD EDGV+ DFD+SVSNFVDNLYGYPEGKDTLRETIKFMYTD
Sbjct: 381 IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTD 440
Query: 427 WADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWAD 486
WAD++NPETRRKTLVALFTDHQWV P+V TADLHA+YGSPTYFYAFYHHCQS MKP+W+D
Sbjct: 441 WADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSD 500
Query: 487 SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKF 546
+AHGDEVPYVFG+PM+GPT+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPN+PVPQDTKF
Sbjct: 501 AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKF 560
Query: 547 IHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
IHTK NRFEEVAWSKYNP+DQLYLHIGLKPRVRDHYRATKVAFW LVPHL+NL+++F Y
Sbjct: 561 IHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHY 620
Query: 607 VSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIE 666
STTTKVPPPD T + TRR K W +TKRPAI+PA + ++++ + +L+E
Sbjct: 621 TSTTTKVPPPDTTHSSHITRRPNGKTW-STKRPAISPAYSNENAQGSWNGDQDAGPLLVE 679
Query: 667 TKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNT-TNDIAHIQ 725
RDYSTELSVTIAVGASLLFLN+LAFAALYY+KDKRR E R+PSPQR ++
Sbjct: 680 NPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAP 739
Query: 726 NEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNT 785
EE+ +LQ+ HECE+ HDTLRLT PDYTLTLRRSPDDIPLMTPNTITMIPN+
Sbjct: 740 EEELAALQLGPTH--HECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNS 797
Query: 786 LTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
L G+Q LH +NTF+ G NST LPH HSTTRV
Sbjct: 798 LVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV 828
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 1221 bits (3159), Expect = 0.0
Identities = 590/789 (74%), Positives = 662/789 (83%), Gaps = 36/789 (4%)
Query: 46 PVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQ 105
P+V TN+GKIRG++ L NEILGPV Q+LGVPYA+PPTGERRFQPPEPPS W+ IRN TQ
Sbjct: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
Query: 106 FAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSK 165
FA VCPQ++ + L MLP+WFT NLD + +YVQDQ+EDCLYLNIYVPTEDDI D
Sbjct: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
Query: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 225
KPVMVYIHGGSYMEGTGN+ DGS+LASYGNVIVIT+NYRLG+LGFLSTGDQAAKGNYGLL
Sbjct: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
Query: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEG---------LFQKA 276
D IQALRW EN+G FGGDP R+T+FGSGAG SCV+LLTLSHYSEG LFQ+A
Sbjct: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
Query: 277 IIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATY 336
I QSGTALSSWAV++QPAKY R+LA KVGCN+ DT ++VECL+ K YKEL+ Q I PA Y
Sbjct: 293 IAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARY 352
Query: 337 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFD 396
HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV+ IVD++DG++ +DFD
Sbjct: 353 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFD 412
Query: 397 FSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVAT 456
F+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD+ NPETRRKTL+ALFTDHQWVAPAVAT
Sbjct: 413 FAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVAT 472
Query: 457 ADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKND 516
ADLH+ +GSPTYFYAFYHHCQ++ P+WAD+AHGDEVPYV GIPMIGPTELF CNFSKND
Sbjct: 473 ADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKND 532
Query: 517 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP 576
VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAW++Y+ KDQLYLHIGLKP
Sbjct: 533 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKP 592
Query: 577 RVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKI---W 633
RV++HYRA KV WLELVPHLHNLN+I QY STTTKVP D+T P TR++ + +
Sbjct: 593 RVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRP--TRKNSVPVTSAF 650
Query: 634 PTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAF 693
PT K+ ++PK P +RDYSTELSVTIAVGASLLFLNILAF
Sbjct: 651 PTAKQ------DDPKQQPSPFSV----------DQRDYSTELSVTIAVGASLLFLNILAF 694
Query: 694 AALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHDHECESLQAHD-TL 752
AALYYKKDKRRH+ HRR SPQR TTND+ H Q EEIMSLQMK + DHECES+ H+ L
Sbjct: 695 AALYYKKDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVL 754
Query: 753 RLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQPLHTFNTFSGGQNST-----NL 807
R CPPDYTL +RRSPDD+PLMTPNTITMIPNT+ G+QPLHTFNTF+GGQN+T
Sbjct: 755 RTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPH 814
Query: 808 PHGHSTTRV 816
PH HSTTRV
Sbjct: 815 PHSHSTTRV 823
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 1033 bits (2671), Expect = 0.0
Identities = 519/816 (63%), Positives = 616/816 (75%), Gaps = 59/816 (7%)
Query: 42 QAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIR 101
+ ++PVVNT YG++RG+R L NEILGPV Q+LGVPYA+PP G RRFQPPE P+SW G+R
Sbjct: 38 EERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVR 97
Query: 102 NTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTED---- 157
N T CPQ+L +L MLP+WFT NL+ TYVQ+Q+EDCLYLN+YVPTED
Sbjct: 98 NATTLPPACPQNL-HGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLT 156
Query: 158 -------------DIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYR 204
DI D KKPVM+++HGGSYMEGTGNM DGS+LA+YGNVIV T+NYR
Sbjct: 157 KKRDEATLNPPDTDIRDPG-KKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYR 215
Query: 205 LGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLT 264
LG+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+R+TIFGSGAGASCV+LL
Sbjct: 216 LGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLI 275
Query: 265 LSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYK 324
LSH+SEGLFQKAI QSGTA+SSW+VNYQP KYTR+LA KVGC+ D+ + VECLR K +
Sbjct: 276 LSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSR 335
Query: 325 ELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIV 384
EL+ Q + PA YHIAFGPV+DGDV+PDDP+ILM+QGEFLNYD+++GVNQGEGLKFV+
Sbjct: 336 ELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSA 395
Query: 385 DNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALF 444
++EDGV+ + FDF+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD++N E RRKTL+ALF
Sbjct: 396 ESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALF 455
Query: 445 TDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGP 504
TDHQWVAPAVATA LHA Y SP YFY FYHHCQ+E +P WAD+AHGDE+PYVFG+PM+G
Sbjct: 456 TDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGA 515
Query: 505 TELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNP 564
T+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEV WSK+N
Sbjct: 516 TDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNS 575
Query: 565 KDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLN-EIFQYVSTTTKVPPPDMTSFPY 623
K++ YLHIGLKPRVRD+YRA KVAFWLELVPHLHNL+ E+F +TTT++P PY
Sbjct: 576 KEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELF---TTTTRLP-------PY 625
Query: 624 GTR---RSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIA 680
TR R PA P T+RP P+ +P GP RDYSTELSVT+A
Sbjct: 626 ATRWPPRPPAGA-PGTRRPPPPATLPPEPEPEP---GPRAYDRFPGDSRDYSTELSVTVA 681
Query: 681 VGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHD 740
VGASLLFLNILAFAALYYK+D+R+ RR SP + + + ++ ++L +
Sbjct: 682 VGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVP--GGGPLLPAAGRELPPE 739
Query: 741 HECESLQAH----------DTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQ 790
E SLQ + LR CPPDYTL LRR+PDD+PL+ P +T++P+ L
Sbjct: 740 EELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPP 799
Query: 791 P-----LHTFNTF-----SGGQNSTNLPHGHSTTRV 816
P LH F F + ++ LPH HSTTRV
Sbjct: 800 PPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV 835
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 323 bits (829), Expect = 3e-88
Identities = 192/564 (34%), Positives = 298/564 (52%), Gaps = 56/564 (9%)
Query: 47 VVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQF 106
++ T GK+RG+ + G V +LG+PYA PP G RF+ P+ + W+ I N T++
Sbjct: 33 IIATKNGKVRGMNLTVFG---GTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKY 89
Query: 107 AAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKK 166
A C Q++D+ +W N +T D +EDCLYLN+++P +
Sbjct: 90 ANSCCQNIDQSFPGFHGSEMW---NPNT------DLSEDCLYLNVWIPAP-----KPKNA 135
Query: 167 PVMVYIHGGSYMEGTGNM--IDGSILASYGNVIVITINYRLGILGFLST-GDQAAKGNYG 223
V+++I+GG + GT ++ DG LA VIV+++NYR+G LGFL+ G+ A GN G
Sbjct: 136 TVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMG 195
Query: 224 LLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTA 283
L DQ AL+W+++N+ AFGG+PK VT+FG AGA+ VSL LS S LF +AI+QSG+
Sbjct: 196 LFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSF 255
Query: 284 LSSWAVN--YQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATY----H 337
+ WAV Y+ T LA GC+ + T++++CLRNK+ +E++ Y
Sbjct: 256 NAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLS 315
Query: 338 IAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV-----DGIVDNEDGVTP 392
+ FGP +DGD + D P IL+E G+F I++GVN+ EG F+ DN +T
Sbjct: 316 VNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITR 375
Query: 393 NDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAP 452
+F + F +P + +E+I F YTDW D + PE R+ L + D+ ++ P
Sbjct: 376 KEFQEGLKIF------FPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICP 429
Query: 453 AVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNF 512
A+ +++G+ +FY F H P W HG E+ +VFG+P+ N+
Sbjct: 430 ALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRD-----NY 484
Query: 513 SKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHI 572
+K + +LS ++ W NFAK G+PN+ T +W + +Q YL +
Sbjct: 485 TKAEEILSRSIVKRWANFAKYGNPNETQNNST-------------SWPVFKSTEQKYLTL 531
Query: 573 GLK-PRVRDHYRATKVAFWLELVP 595
+ R+ RA + FW P
Sbjct: 532 NTESTRIMTKLRAQQCRFWTSFFP 555
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 320 bits (821), Expect = 3e-87
Identities = 213/643 (33%), Positives = 312/643 (48%), Gaps = 74/643 (11%)
Query: 1 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT 60
M PQ LL P L +P+ ++L LWL + + +V G++RG+R
Sbjct: 1 MRPPQCLLHTPSLASPLLLLL-----LWLLGGGVGAE--GREDAELLVTVRGGRLRGIRL 53
Query: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL 120
P GPV +LG+P+A PP G RRF PPEP W+G+ + T F +VC Q++D
Sbjct: 54 KTPG---GPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPG 110
Query: 121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG 180
+ +W ++ +EDCLYLN++ P S PV+V+I+GG + G
Sbjct: 111 FEGTEMWNPN---------RELSEDCLYLNVWTPYPRP----TSPTPVLVWIYGGGFYSG 157
Query: 181 TGNM--IDGSILASYGNVIVITINYRLGILGFLST-GDQAAKGNYGLLDQIQALRWIEEN 237
++ DG L +++++NYR+G GFL+ G + A GN GLLDQ AL+W++EN
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217
Query: 238 VGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAV--NYQPAK 295
V AFGGDP VT+FG AGA+ V + LS S GLF +A++QSG WA + +
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277
Query: 296 YTRILADKVGCNMLDT----TDMVECLRNKNYKELIQQT--ITP--ATYHIAFGPVIDGD 347
LA VGC T T++V CLR + + L+ + P + + +F PV+DGD
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337
Query: 348 VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV-----DGIVDNEDGVTPNDFDFSVSNF 402
+ D P+ L+ G+F +++GV + EG F+ DNE ++ +F V
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVR-- 395
Query: 403 VDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQ 462
G P+ D E + YTDW E+P R+ L + DH V P A A
Sbjct: 396 ----VGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAA 451
Query: 463 YGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAV 522
G+ Y Y F H + P W HG E+ ++FGIP+ S N++ + + +
Sbjct: 452 QGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDP-----SRNYTAEEKIFAQR 506
Query: 523 VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP-RVRDH 581
+M YW NFA+TGDPN+ P+D K W Y Q Y+ + L+P VR
Sbjct: 507 LMRYWANFARTGDPNE--PRDPK----------APQWPPYTAGAQQYVSLDLRPLEVRRG 554
Query: 582 YRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYG 624
RA AFW +P L +S T P F +G
Sbjct: 555 LRAQACAFWNRFLPKL---------LSATASEAPSTCPGFTHG 588
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 319 bits (818), Expect = 6e-87
Identities = 208/616 (33%), Positives = 305/616 (49%), Gaps = 65/616 (10%)
Query: 1 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT 60
M PQ LL P L +P+ ++L LWL + + +V G++RG+R
Sbjct: 1 MRPPQCLLHTPSLASPLLLLL-----LWLLGGGVGAE--GREDAELLVTVRGGRLRGIRL 53
Query: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL 120
P GPV +LG+P+A PP G RRF PPEP W+G+ + T F +VC Q++D
Sbjct: 54 KTPG---GPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPG 110
Query: 121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG 180
+ +W ++ +EDCLYLN++ P S PV+V+I+GG + G
Sbjct: 111 FEGTEMWNPN---------RELSEDCLYLNVWTPYPRP----TSPTPVLVWIYGGGFYSG 157
Query: 181 TGNM--IDGSILASYGNVIVITINYRLGILGFLST-GDQAAKGNYGLLDQIQALRWIEEN 237
++ DG L +++++NYR+G GFL+ G + A GN GLLDQ AL+W++EN
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217
Query: 238 VGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAV--NYQPAK 295
V AFGGDP VT+FG AGA+ V + LS S GLF +A++QSG WA + +
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277
Query: 296 YTRILADKVGCNMLDT----TDMVECLRNKNYKELIQQT--ITP--ATYHIAFGPVIDGD 347
LA VGC T T++V CLR + + L+ + P + + +F PV+DGD
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337
Query: 348 VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV-----DGIVDNEDGVTPNDFDFSVSNF 402
+ D P+ L+ G+F +++GV + EG F+ DNE ++ +F V
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVR-- 395
Query: 403 VDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQ 462
G P+ D E + YTDW E+P R+ L + DH V P A A
Sbjct: 396 ----VGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAA 451
Query: 463 YGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAV 522
G+ Y Y F H + P W HG E+ ++FGIP+ S N++ + + +
Sbjct: 452 QGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDP-----SRNYTAEEKIFAQR 506
Query: 523 VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP-RVRDH 581
+M YW NFA+TGDPN+ P+D K W Y Q Y+ + L+P VR
Sbjct: 507 LMRYWANFARTGDPNE--PRDPK----------APQWPPYTAGAQQYVSLDLRPLEVRRG 554
Query: 582 YRATKVAFWLELVPHL 597
RA AFW +P L
Sbjct: 555 LRAQACAFWNRFLPKL 570
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 294 bits (753), Expect = 2e-79
Identities = 192/578 (33%), Positives = 294/578 (50%), Gaps = 61/578 (10%)
Query: 31 ALAIKFTLIDSQAQ---YPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERR 87
A + L+ Q Q P+ T+ G++ G + G V+ +LG+P+A PP G R
Sbjct: 78 ACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLR 136
Query: 88 FQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQ-NEDC 146
F PPEPP SW+G+R+ T A+C L D+ + MT+ D +EDC
Sbjct: 137 FAPPEPPESWSGVRDGTTHPAMC---------LQDLTAVESEFLSQFNMTFPSDSMSEDC 187
Query: 147 LYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLG 206
LYL+IY P + S PVMV+IHGG+ + G ++ DGS+LA+ NV+V+ I YRLG
Sbjct: 188 LYLSIYTPAHSH---EGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLG 244
Query: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266
+LGF STGD+ A GN+G LDQ+ ALRW+++N+ FGG+P RVTIFG AG + VS L +S
Sbjct: 245 VLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVS 304
Query: 267 HYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKEL 326
S+GLF AI++SG AL + + ++A+ C+ +D+ +V CLR K+ +E+
Sbjct: 305 PISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEI 364
Query: 327 IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG---LKFVDGI 383
+ + + G V+DG +P PQ L+ +F ++GVN E + V I
Sbjct: 365 L---AINKPFKMIPG-VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420
Query: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
D + + ++ + L P D LRE D +P+T + +
Sbjct: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDNGDPQTLQAQFQEM 474
Query: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQ--SEMKPSWADSAHGDEVPYVFGIPM 501
D +V PA+ A +P YFY F H ++P + HGDE+P+VF
Sbjct: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVF---- 529
Query: 502 IGPTELFSCN---FSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEV 557
F N F++ + LS +M YW NFA+ G+PN + +P
Sbjct: 530 ---RSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH--------------- 571
Query: 558 AWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
W ++ ++Q YL + L+P V +A ++ FW + +P
Sbjct: 572 -WPLFDQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 607
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 293 bits (749), Expect = 6e-79
Identities = 199/588 (33%), Positives = 294/588 (50%), Gaps = 60/588 (10%)
Query: 27 LWLTALAIKFTLIDSQA-----QYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASP 81
+WL A + TL S A PVV+T +GK+ G L PV +LG+P+A P
Sbjct: 1 MWLRAFILA-TLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKP 58
Query: 82 PTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQD 141
P G RF PP+P W+ ++N T + +C Q LL ++ FT + + +
Sbjct: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSEL----FTNRKENIPLKL-- 112
Query: 142 QNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITI 201
+EDCLYLNIY P D+ +N + PVMV+IHGG M G + DG LA++ NV+V+TI
Sbjct: 113 -SEDCLYLNIYTPA--DLTKKN-RLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI 168
Query: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
YRLGI GF STGD+ ++GN+G LDQ+ ALRW+++N+ +FGG+P VTIFG AG VS
Sbjct: 169 QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVS 228
Query: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLRN 320
+L LS ++ LF +AI +SG AL+S V K +A GC + MV CLR
Sbjct: 229 VLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQ 288
Query: 321 KNYKELIQQTI-----------TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIML 369
K +EL++ T+ P G VIDG ++ P+ L + F M+
Sbjct: 289 KTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMV 348
Query: 370 GVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRE-TIKFMYTDWA 428
G+N+ E + ++ D ++S + K+ + E T K++
Sbjct: 349 GINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYL----G 404
Query: 429 DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWAD 486
++ ++ + L D + P+V A H G+PTY Y F + S+MKP
Sbjct: 405 GTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVI 464
Query: 487 SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTK 545
HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN + +P
Sbjct: 465 GDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH--- 515
Query: 546 FIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
W +YN K+ YL IG + + +VAFW L
Sbjct: 516 -------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 549
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 291 bits (746), Expect = 1e-78
Identities = 200/597 (33%), Positives = 294/597 (49%), Gaps = 77/597 (12%)
Query: 27 LWLTALAIKFTLIDSQA-----QYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASP 81
+WL A + TL S A PVV+T +GK+ G L PV +LG+P+A P
Sbjct: 1 MWLRAFILA-TLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKP 58
Query: 82 PTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQD 141
P G RF PP+P W+ ++N T + +C Q LL ++ FT + + +
Sbjct: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSEL----FTNRKENIPLKL-- 112
Query: 142 QNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITI 201
+EDCLYLNIY P D+ +N + PVMV+IHGG M G + DG LA++ NV+V+TI
Sbjct: 113 -SEDCLYLNIYTPA--DLTKKN-RLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI 168
Query: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
YRLGI GF STGD+ ++GN+G LDQ+ ALRW+++N+ +FGG+P VTIFG AG VS
Sbjct: 169 QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVS 228
Query: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLRN 320
+L LS ++ LF +AI +SG AL+S V K +A GC + MV CLR
Sbjct: 229 VLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQ 288
Query: 321 KNYKELIQQTI-----------TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIML 369
K +EL++ T+ P G VIDG ++ P+ L + F M+
Sbjct: 289 KTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMV 348
Query: 370 GVNQGE----------GLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRET 419
G+N+ E +G +D + ++ + + L PE T
Sbjct: 349 GINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKEL--IPEA------T 400
Query: 420 IKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQ 477
K++ ++ ++ + L D + P+V A H G+PTY Y F +
Sbjct: 401 EKYL----GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFS 456
Query: 478 SEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
S+MKP HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN
Sbjct: 457 SDMKPKTVIGDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPN 510
Query: 538 -QPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
+ +P W +YN K+ YL IG + + +VAFW L
Sbjct: 511 GEGLPH----------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 550
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 291 bits (745), Expect = 2e-78
Identities = 193/573 (33%), Positives = 285/573 (49%), Gaps = 71/573 (12%)
Query: 46 PVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQ 105
PVV+T +GK+ G L PV +LG+P+A PP G RF PP+P W+ ++N T
Sbjct: 25 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 83
Query: 106 FAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSK 165
+ +C Q LL ++ FT + + + +EDCLYLNIY P D+ +N +
Sbjct: 84 YPPMCTQDPKAGQLLSEL----FTNRKENIPLKL---SEDCLYLNIYTPA--DLTKKN-R 133
Query: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 225
PVMV+IHGG M G + DG LA++ NV+V+TI YRLGI GF STGD+ ++GN+G L
Sbjct: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193
Query: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 285
DQ+ ALRW+++N+ +FGG+P VTIFG AG VS+L LS ++ LF +AI +SG AL+
Sbjct: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 253
Query: 286 SWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTI-----------TP 333
S V K +A GC + MV CLR K +EL++ T+ P
Sbjct: 254 SVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDP 313
Query: 334 ATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE----------GLKFVDGI 383
G VIDG ++ P+ L + F M+G+N+ E +G
Sbjct: 314 RESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQ 373
Query: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
+D + ++ + + L PE T K++ ++ ++ + L
Sbjct: 374 LDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL----GGTDDTVKKKDLFLDL 421
Query: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWADSAHGDEVPYVFGIPM 501
D + P+V A H G+PTY Y F + S+MKP HGDE+ VFG P
Sbjct: 422 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 481
Query: 502 IGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWS 560
+ S+ ++ LS +VM +W NFA+ G+PN + +P W
Sbjct: 482 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 519
Query: 561 KYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
+YN K+ YL IG + + +VAFW L
Sbjct: 520 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 551
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 288 bits (736), Expect = 2e-77
Identities = 190/573 (33%), Positives = 294/573 (51%), Gaps = 48/573 (8%)
Query: 27 LWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGER 86
+W+ A K A+ P NT G I+G + + + PV +LGVP+A+PP G
Sbjct: 16 IWVLAAPTK----GPSAEGPQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPPLGSL 70
Query: 87 RFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDC 146
RF P+P S W +R T + +C Q+ + L ML + + +EDC
Sbjct: 71 RFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSEDC 121
Query: 147 LYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLG 206
LYLNIY P D SK PV+V+ GG++ G+ ++ DGS LA+Y +V+V+ + YRLG
Sbjct: 122 LYLNIYAPAHADT---GSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLG 178
Query: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266
I GF +T DQ A GN+ DQ+ AL W+++N+ FGGDP VTIFG AGA VS L LS
Sbjct: 179 IFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILS 238
Query: 267 HYSEGLFQKAIIQSGTALSSW--AVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYK 324
++GLF KAI++SG A+ + A +Y+ ++ +++A G N D+ ++ CLR K K
Sbjct: 239 PMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSK 298
Query: 325 ELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIV 384
EL+ T++ T +F V+DG P++P L+ Q F ++GVN E F+ +
Sbjct: 299 ELL--TLSQKTK--SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPMK 353
Query: 385 DNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALF 444
+ + ++ ++ ++ + + N+ P L F DK + R +L+ L
Sbjct: 354 EAPEILSGSNKSLAL-HLIQNILHIPPQYLHLVANEYF-----HDKHSLTEIRDSLLDLL 407
Query: 445 TDHQWVAPAVATADLHAQYGSPTYFYAFYH--HCQSEMKPSWADSAHGDEVPYVFGIPMI 502
D +V PA+ TA H G+P YFY F H C + KP++ + H DEV +VFG +
Sbjct: 408 GDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFL 467
Query: 503 GPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKY 562
+ ++ + +LS +M YW FA+TG+PN + W Y
Sbjct: 468 KGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPAY 512
Query: 563 NPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
N +Q YL + L + + +V FW +P
Sbjct: 513 NLTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIP 544
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 283 bits (724), Expect = 5e-76
Identities = 187/522 (35%), Positives = 264/522 (50%), Gaps = 63/522 (12%)
Query: 39 IDSQAQYPVVNTNYGKIRGLRTPLPNEILGP-VEQYLGVPYASPPTGERRFQPPEPPSSW 97
+ S A+ V T G + G+ L +LG V+ + G+P+A+P + + P+P W
Sbjct: 20 VASAAKLGAVYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFAAPT---KALENPQPHPGW 74
Query: 98 TGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTED 157
G F C Q A + TY +EDCLYLNI+VP
Sbjct: 75 QGTLKAKNFKKRCLQ-----------------ATITQDSTY---GDEDCLYLNIWVPQG- 113
Query: 158 DIHDQNSKK-PVMVYIHGGSYMEGTGN--------MIDGSILASYGNVIVITINYRLGIL 208
Q S+ PVM++I+GG+++ G+G+ + DG +A+ GNVIV+T NYR+G L
Sbjct: 114 --RKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPL 171
Query: 209 GFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHY 268
GFLSTGD GNYGL DQ A+ W++ N+ AFGGDP +T+FG AG + VSL TLS Y
Sbjct: 172 GFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPY 231
Query: 269 SEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKN------ 322
++GL ++AI QSG ALS W + P + + +A+KVGC + D M +CL+ +
Sbjct: 232 NKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTL 291
Query: 323 -YKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKF-- 379
YK + P +++ F PVIDGD IP DP L ++Y + G N +G F
Sbjct: 292 AYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDY--IAGTNNMDGHIFAS 349
Query: 380 --VDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRR 437
+ I VT DF VS F +G + T WA + E ++
Sbjct: 350 IDMPAINKGNKKVTEEDFYKLVSEFT-----ITKGLRGAKTTFDVYTESWAQDPSQENKK 404
Query: 438 KTLVALFTDHQWVAPA-VATADLHAQYGS-PTYFYAFYHHCQSEMKPSWADSAHGDEVPY 495
KT+V TD ++ P +A A A S TY Y F H + + P W + H D++ Y
Sbjct: 405 KTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQY 464
Query: 496 VFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
VFG P PT + D +S ++ YWTNFAKTGDPN
Sbjct: 465 VFGKPFATPT-----GYRPQDRTVSKAMIAYWTNFAKTGDPN 501
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 283 bits (724), Expect = 5e-76
Identities = 186/592 (31%), Positives = 289/592 (48%), Gaps = 59/592 (9%)
Query: 19 VMLNSNVLLWLTAL--AIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGV 76
V + S VL+ + L A T + P V+T G++RG + + V +LG+
Sbjct: 5 VRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDR-LVNVFLGI 63
Query: 77 PYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLM 136
P+A PP G RF P P W G+R+ + +C Q ++ + +L
Sbjct: 64 PFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVL---------NGK 114
Query: 137 TYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNV 196
+ +EDCL LN+Y P E S +PVMV++HGG+ + G DGS LA+YG+V
Sbjct: 115 QQIFSVSEDCLVLNVYSPAEVPA---GSGRPVMVWVHGGALITGAATSYDGSALAAYGDV 171
Query: 197 IVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAG 256
+V+T+ YRLG+LGF STGD+ A GN G LD + ALRW++EN+ FGGD VT+FG AG
Sbjct: 172 VVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAG 231
Query: 257 ASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVE 316
S +S L LS + GLF +AI QSG + ++ P + +A+ + C+ +MV+
Sbjct: 232 GSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQ 291
Query: 317 CLRNKNYKELI-----QQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGV 371
CL+ K +EL+ + TI P T +DG V P P+ L+++ F + ++GV
Sbjct: 292 CLQQKEGEELVLSKKLKNTIYPLT--------VDGTVFPKSPKELLKEKPFHSVPFLMGV 343
Query: 372 NQGEGLKFVD---GIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA 428
N E + G++D + ++ D + + +L PE T+ +
Sbjct: 344 NNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEY------LG 397
Query: 429 DKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS--EMKPSWAD 486
+ + + + D P V+ + GSP +FY F H S ++KP+W
Sbjct: 398 SNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVK 457
Query: 487 SAHGDEVPYVFGIP--MIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQD 543
+ HG E +VFG P M + L ++ + LS +M WT+FA+TGDPN + +P
Sbjct: 458 ADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALP-- 515
Query: 544 TKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
W ++N +Q YL I PR +R + FW E +P
Sbjct: 516 --------------PWPQFNQAEQ-YLEINPVPRAGQKFREAWMQFWSETLP 552
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 280 bits (717), Expect = 3e-75
Identities = 185/573 (32%), Positives = 286/573 (49%), Gaps = 67/573 (11%)
Query: 31 ALAIKFTLIDSQAQ---YPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERR 87
A + L+ Q Q P+ T+ G++ G + G V+ +LG+P+A PP G R
Sbjct: 78 ACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLR 136
Query: 88 FQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQ-NEDC 146
F PPEPP SW+G+R+ T A+C L D+ + MT+ D +EDC
Sbjct: 137 FAPPEPPESWSGVRDGTTHPAMC---------LQDLTAVESEFLSQFNMTFPSDSMSEDC 187
Query: 147 LYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLG 206
LYL+IY P + S PVMV+IHGG+ + G ++ DGS+LA+ NV+V+ I YRLG
Sbjct: 188 LYLSIYTPAHSH---EGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLG 244
Query: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266
+LGF STGD+ A GN+G LDQ+ ALRW+++N+ FGG+P RVTIFG AG + VS L +S
Sbjct: 245 VLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVS 304
Query: 267 HYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKEL 326
S+GLF AI++SG AL + + ++A+ C+ +D+ +V CLR K+ +E+
Sbjct: 305 PISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEI 364
Query: 327 IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG---LKFVDGI 383
+ + + G V+DG +P PQ L+ +F ++GVN E + V I
Sbjct: 365 L---AINKPFKMIPG-VVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRI 420
Query: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
D + + ++ + L P D LRE D +P+T + +
Sbjct: 421 YDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDNGDPQTLQAQFQEM 474
Query: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIG 503
D +V PA+ A +P YFY F H +PSW + +
Sbjct: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQH------QPSWLKNIRPPHM---------- 517
Query: 504 PTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWSKY 562
+ F++ + LS +M YW NFA+ G+PN + +P W +
Sbjct: 518 --KADHVKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----------------WPLF 559
Query: 563 NPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
+ ++Q YL + L+P V +A ++ FW + +P
Sbjct: 560 DQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 591
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 239 bits (610), Expect = 7e-63
Identities = 176/571 (30%), Positives = 271/571 (47%), Gaps = 94/571 (16%)
Query: 27 LWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGER 86
+W+ A K A+ P NT G I+G + + + PV +LGVP+A+PP G
Sbjct: 16 IWVLAAPTK----GPSAEGPQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPPLGSL 70
Query: 87 RFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDC 146
RF P+P S W +R T + +C Q+ + L ML + + +EDC
Sbjct: 71 RFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSEDC 121
Query: 147 LYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLG 206
LYLNIY P D SK PV+V+ GG++ G+ ++ DGS LA+Y +V+V+ + YRLG
Sbjct: 122 LYLNIYAPAHADT---GSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLG 178
Query: 207 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS 266
I GF +T DQ A GN+ DQ+ AL W+++N+ FGGDP VTIFG AGA VS L LS
Sbjct: 179 IFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILS 238
Query: 267 HYSEGLFQKAIIQSGTALSSW--AVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYK 324
++GLF KAI++SG A+ + A +Y+ ++ +++A G N D+ ++ CLR K K
Sbjct: 239 PMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSK 298
Query: 325 ELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIV 384
EL+ T++ T +F V+DG P++P L+ Q F ++GVN E F+ +
Sbjct: 299 ELL--TLSQKTK--SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPMK 353
Query: 385 DNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALF 444
+ + ++ ++ ++ + + N+ P L F DK + R +L+ L
Sbjct: 354 EAPEILSGSNKSLAL-HLIQNILHIPPQYLHLVANEYF-----HDKHSLTEIRDSLLDLL 407
Query: 445 TDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGP 504
D +V PA+ TA H + G
Sbjct: 408 GDVFFVVPALITARYHRE----------------------------------------GA 427
Query: 505 TELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNP 564
TE + +LS +M YW FA+TG+PN + W YN
Sbjct: 428 TE--------EEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPAYNL 464
Query: 565 KDQLYLHIGLKPRVRDHYRATKVAFWLELVP 595
+Q YL + L + + +V FW +P
Sbjct: 465 TEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIP 494
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 231 bits (588), Expect = 3e-60
Identities = 139/370 (37%), Positives = 196/370 (52%), Gaps = 39/370 (10%)
Query: 25 VLLWLTALAI--KFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPP 82
+L W L + + L + P V T YG ++G + + P++ +LGVP++ PP
Sbjct: 4 ILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRPP 60
Query: 83 TGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQ 142
G RF PPEPP W GIR+ T + C Q W L ++ +++
Sbjct: 61 LGILRFAPPEPPEPWKGIRDATTYPPGCLQES------------W--GQLASMYVSTRER 106
Query: 143 ------NEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNV 196
+EDCLYLN+Y P Q PVMV+ GG+++ G + +GS LA+ V
Sbjct: 107 YKWLRFSEDCLYLNVYAPARAPGDPQ---LPVMVWFPGGAFIVGAASSYEGSDLAAREKV 163
Query: 197 IVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAG 256
+++ + +RLGI GFLST D A+GN+GLLDQ+ ALRW++EN+ AFGGDP VT+FG AG
Sbjct: 164 VLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAG 223
Query: 257 ASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVE 316
A +S L +S + GLF +AI QSGTAL + P K + +A GCN T +V
Sbjct: 224 AMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVN 283
Query: 317 CLRN---------KNYKELIQQTI--TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNY 365
CLR N +Q P + PV+DG VIPDDP +L+ QG+ +
Sbjct: 284 CLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSV 343
Query: 366 DIMLGVNQGE 375
+LGVN E
Sbjct: 344 PYLLGVNNLE 353
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 16/75 (21%)
Query: 519 LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRV 578
LS +M YW NFA+TG+PN W +YN KD+ YL + RV
Sbjct: 421 LSLQMMKYWANFARTGNPNDG---------------NLPCWPRYN-KDEKYLQLDFTTRV 464
Query: 579 RDHYRATKVAFWLEL 593
+ K+AFW+ L
Sbjct: 465 GMKLKEKKMAFWMSL 479
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 193 bits (490), Expect = 6e-49
Identities = 142/481 (29%), Positives = 233/481 (48%), Gaps = 45/481 (9%)
Query: 70 VEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFT 129
V+Q+LGVPYA+PP ERRFQ PEP +WTG + ++ A C Q
Sbjct: 2225 VDQFLGVPYAAPPLAERRFQAPEP-LNWTGSWDASKPRASCWQP---------------- 2267
Query: 130 ANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNM--IDG 187
T + +EDCLYLN+++P + V+V+ H E + IDG
Sbjct: 2268 ---GTRTSTSPGVSEDCLYLNVFIP-----QNVAPNASVLVFFHNTMDREESEGWPAIDG 2319
Query: 188 SILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKR 247
S LA+ GN+IV+T +YR+G+ GFLS+G GN+GLLDQ+ AL W++ ++ FGGDP+R
Sbjct: 2320 SFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRR 2379
Query: 248 VTIFGSGAGASCVS--LLTLSHYSEGLFQKAIIQSGTALSSWAV-NYQPAKYTRI-LADK 303
V++ GA S LLT + LF++A++ G+ALS AV +++ A+ I LA +
Sbjct: 2380 VSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKE 2439
Query: 304 VGCNMLDTTDMVECLRNKNYKEL----IQQTITPATYHIAFGPVIDGDVIPDDPQILMEQ 359
V C M + ++V CLR K L + +H +GPVIDG + + P +++
Sbjct: 2440 VSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY-WGPVIDGHFLREPPARALKR 2498
Query: 360 GEFLNYDIMLGVNQGEGL-KFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRE 418
++ D+++G +Q +GL + E+ + + N G + +
Sbjct: 2499 SLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEA 2558
Query: 419 TIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQS 478
+ Y+ ++ + + L D+ + P + A A+ F YH ++
Sbjct: 2559 AATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVF--MYHAPEN 2616
Query: 479 EMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQ 538
S A +V + G+P + FS + LS +M Y+++F ++G+PN
Sbjct: 2617 YGHGSLELLA---DVQFALGLPFY---PAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNY 2670
Query: 539 P 539
P
Sbjct: 2671 P 2671
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 155 bits (392), Expect = 1e-37
Identities = 84/204 (41%), Positives = 127/204 (62%), Gaps = 6/204 (2%)
Query: 174 GGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRW 233
GG++ G+ ++ DGS LA+Y +++V+ + YRLGI GF +T DQ A GN+ DQ+ AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 234 IEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSW--AVNY 291
+++N+ FGGDP VTIFG GA VS L LS +EGLF KA+++SG A+ + A +Y
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 292 QPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPD 351
+ ++ +++A G N D+ + CLR K+ KEL+ T++ T AF V+DG P+
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELL--TLSQKTK--AFTQVVDGAFFPN 195
Query: 352 DPQILMEQGEFLNYDIMLGVNQGE 375
+P L+ Q F ++GVN E
Sbjct: 196 EPLDLLSQKAFKAIPSIIGVNNPE 219
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 155 bits (392), Expect = 1e-37
Identities = 84/204 (41%), Positives = 127/204 (62%), Gaps = 6/204 (2%)
Query: 174 GGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRW 233
GG++ G+ ++ DGS LA+Y +++V+ + YRLGI GF +T DQ A GN+ DQ+ AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 234 IEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSW--AVNY 291
+++N+ FGGDP VTIFG GA VS L LS +EGLF KA+++SG A+ + A +Y
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 292 QPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPD 351
+ ++ +++A G N D+ + CLR K+ KEL+ T++ T AF V+DG P+
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELL--TLSQKTK--AFTQVVDGAFFPN 195
Query: 352 DPQILMEQGEFLNYDIMLGVNQGE 375
+P L+ Q F ++GVN E
Sbjct: 196 EPLDLLSQKAFKAIPSIIGVNNPE 219
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 92.0 bits (227), Expect = 2e-18
Identities = 39/84 (46%), Positives = 60/84 (71%)
Query: 168 VMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQ 227
V+++ GG++ G+ ++ DGS LA+Y +++V+ + YRLGI GF +T DQ A GN+ DQ
Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79
Query: 228 IQALRWIEENVGAFGGDPKRVTIF 251
+ AL W+++N+ FGGDP VTIF
Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIF 103
>gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase
6 [Homo sapiens]
Length = 395
Score = 34.3 bits (77), Expect = 0.48
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 1/86 (1%)
Query: 559 WSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDM 618
W+ + LH+ ++ VR + F L P NL+++FQ+ + PP
Sbjct: 77 WTTLSQGSAATLHMAVRDLVRSVFLCDMDVFDAYL-PWRRNLSDLFQWAVSRALCSPPAC 135
Query: 619 TSFPYGTRRSPAKIWPTTKRPAITPA 644
++FP G S A P R + T A
Sbjct: 136 SAFPRGAISSEAVCKPLCARQSFTLA 161
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 33.5 bits (75), Expect = 0.82
Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 10/151 (6%)
Query: 639 PAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYY 698
P P++ P HS H P VL DY+T S + A A NI L
Sbjct: 744 PQFFPSSPPPHSPLSHGHIPS-AIVLPNATHDYNTSFSNSNAHKAEKKLQNI--DHPLTK 800
Query: 699 KKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQ--MKQLEHDHECESLQAHDTLRLTC 756
KR HRR RNT ND+ N+ + + M ++ H+ L ++
Sbjct: 801 SSSKR---DHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVP 857
Query: 757 P--PDYTLTLRRSPDDIPLMTPNTITMIPNT 785
P P+ +L P +P +P +P T
Sbjct: 858 PKVPNREASLYSPPSTLPRNSPTKRVDVPTT 888
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 33.5 bits (75), Expect = 0.82
Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 10/151 (6%)
Query: 639 PAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYY 698
P P++ P HS H P VL DY+T S + A A NI L
Sbjct: 806 PQFFPSSPPPHSPLSHGHIPS-AIVLPNATHDYNTSFSNSNAHKAEKKLQNI--DHPLTK 862
Query: 699 KKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQ--MKQLEHDHECESLQAHDTLRLTC 756
KR HRR RNT ND+ N+ + + M ++ H+ L ++
Sbjct: 863 SSSKR---DHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVP 919
Query: 757 P--PDYTLTLRRSPDDIPLMTPNTITMIPNT 785
P P+ +L P +P +P +P T
Sbjct: 920 PKVPNREASLYSPPSTLPRNSPTKRVDVPTT 950
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 33.5 bits (75), Expect = 0.82
Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 10/151 (6%)
Query: 639 PAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYY 698
P P++ P HS H P VL DY+T S + A A NI L
Sbjct: 750 PQFFPSSPPPHSPLSHGHIPS-AIVLPNATHDYNTSFSNSNAHKAEKKLQNI--DHPLTK 806
Query: 699 KKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQ--MKQLEHDHECESLQAHDTLRLTC 756
KR HRR RNT ND+ N+ + + M ++ H+ L ++
Sbjct: 807 SSSKR---DHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVP 863
Query: 757 P--PDYTLTLRRSPDDIPLMTPNTITMIPNT 785
P P+ +L P +P +P +P T
Sbjct: 864 PKVPNREASLYSPPSTLPRNSPTKRVDVPTT 894
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 33.5 bits (75), Expect = 0.82
Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 10/151 (6%)
Query: 639 PAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYY 698
P P++ P HS H P VL DY+T S + A A NI L
Sbjct: 731 PQFFPSSPPPHSPLSHGHIPS-AIVLPNATHDYNTSFSNSNAHKAEKKLQNI--DHPLTK 787
Query: 699 KKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQ--MKQLEHDHECESLQAHDTLRLTC 756
KR HRR RNT ND+ N+ + + M ++ H+ L ++
Sbjct: 788 SSSKR---DHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVP 844
Query: 757 P--PDYTLTLRRSPDDIPLMTPNTITMIPNT 785
P P+ +L P +P +P +P T
Sbjct: 845 PKVPNREASLYSPPSTLPRNSPTKRVDVPTT 875
>gi|10937869 survival of motor neuron 2, centromeric isoform d [Homo
sapiens]
Length = 294
Score = 32.3 bits (72), Expect = 1.8
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 16/94 (17%)
Query: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPP---SSW-----TGIRNTTQFAAVCPQ 112
P+P LGP + G+ + PP PP PP S W +G +CP
Sbjct: 199 PMPGPRLGPGKP--GLKFNGPPPPP----PPPPPHLLSCWLPPFPSGPPIIPPPPPICPD 252
Query: 113 HLDERSLLHDMLPIWFTANLDT--LMTYVQDQNE 144
LD+ L ML W+ + T M + Q+Q E
Sbjct: 253 SLDDADALGSMLISWYMSGYHTGYYMGFRQNQKE 286
>gi|4507091 survival of motor neuron 1, telomeric isoform d [Homo
sapiens]
Length = 294
Score = 32.3 bits (72), Expect = 1.8
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 16/94 (17%)
Query: 61 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPP---SSW-----TGIRNTTQFAAVCPQ 112
P+P LGP + G+ + PP PP PP S W +G +CP
Sbjct: 199 PMPGPRLGPGKP--GLKFNGPPPPP----PPPPPHLLSCWLPPFPSGPPIIPPPPPICPD 252
Query: 113 HLDERSLLHDMLPIWFTANLDT--LMTYVQDQNE 144
LD+ L ML W+ + T M + Q+Q E
Sbjct: 253 SLDDADALGSMLISWYMSGYHTGYYMGFRQNQKE 286
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,690,555
Number of Sequences: 37866
Number of extensions: 1690819
Number of successful extensions: 4613
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 4138
Number of HSP's gapped (non-prelim): 401
length of query: 816
length of database: 18,247,518
effective HSP length: 111
effective length of query: 705
effective length of database: 14,044,392
effective search space: 9901296360
effective search space used: 9901296360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.