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Search of human proteins with 31083180
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
(538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 1144 0.0
gi|11141869 interleukin 21 receptor precursor [Homo sapiens] 1144 0.0
gi|31083180 interleukin 21 receptor precursor [Homo sapiens] 1144 0.0
gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens] 81 3e-15
gi|29171682 interleukin 9 receptor precursor [Homo sapiens] 69 1e-11
gi|4503591 erythropoietin receptor precursor [Homo sapiens] 57 4e-08
gi|4557669 interleukin 4 receptor alpha chain isoform a precurso... 53 6e-07
gi|28610151 interleukin 7 receptor precursor [Homo sapiens] 53 8e-07
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 51 2e-06
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 51 2e-06
gi|40254464 leptin receptor isoform 1 [Homo sapiens] 51 2e-06
gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo sapi... 51 2e-06
gi|4559408 colony stimulating factor 2 receptor, beta precursor ... 50 7e-06
gi|4885491 myeloproliferative leukemia virus oncogene precursor ... 49 9e-06
gi|56788411 interleukin 4 receptor alpha chain isoform b precurs... 45 1e-04
gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo sapi... 44 3e-04
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens] 44 5e-04
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H... 42 0.001
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H... 42 0.001
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 41 0.003
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 40 0.007
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 37 0.035
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi... 37 0.046
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap... 37 0.046
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 37 0.060
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens] 36 0.10
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 36 0.10
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 35 0.17
gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [H... 35 0.17
gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [H... 35 0.17
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 1144 bits (2958), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60
MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
Sbjct: 1 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60
Query: 61 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120
EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
Sbjct: 61 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120
Query: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
Sbjct: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300
LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
Sbjct: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300
Query: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360
LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
Sbjct: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360
Query: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420
SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
Sbjct: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420
Query: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480
AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
Sbjct: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480
Query: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
Sbjct: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 1144 bits (2958), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60
MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
Sbjct: 1 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60
Query: 61 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120
EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
Sbjct: 61 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120
Query: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
Sbjct: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300
LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
Sbjct: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300
Query: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360
LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
Sbjct: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360
Query: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420
SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
Sbjct: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420
Query: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480
AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
Sbjct: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480
Query: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
Sbjct: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 1144 bits (2958), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60
MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
Sbjct: 1 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60
Query: 61 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120
EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
Sbjct: 61 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120
Query: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
Sbjct: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300
LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
Sbjct: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300
Query: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360
LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
Sbjct: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360
Query: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420
SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
Sbjct: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420
Query: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480
AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
Sbjct: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480
Query: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
Sbjct: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
>gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]
Length = 551
Score = 80.9 bits (198), Expect = 3e-15
Identities = 99/380 (26%), Positives = 158/380 (41%), Gaps = 74/380 (19%)
Query: 5 WAAPLLLLLLQ--GGW------GCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYE 56
W PLL+LLL W G C+ + + C+ W+ Q
Sbjct: 8 WRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCV---WS------------QDG 52
Query: 57 ELKDEATSCSLH----RSAHNAT-------HATYTCHM-----DVFHFMADDIFSVNITD 100
L+D TSC +H R N T A++ C++ D DI ++ +
Sbjct: 53 ALQD--TSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLC 110
Query: 101 QSGNYSQECG--SFLLAESIKPAPPFNVTVTF--SGQYNISWRSDYEDPAFYMLKGKLQY 156
+ G + F E+++ P ++ V + + NISW A + + L++
Sbjct: 111 REGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ---ASHYFERHLEF 167
Query: 157 ELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSE 216
E + + G W +P L+++ + + D+ YE QVR P+ G TWS
Sbjct: 168 EARTLSPGHTWEEAP---LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT--TWSP 222
Query: 217 WSDPVIFQTQSEELKEG---WNPHLLLLLLLVIVFIPAFWSLKTHPLWRLW-KKIWA--V 270
WS P+ F+T+ L + W HLL+ L FI + L W KK+
Sbjct: 223 WSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNT 282
Query: 271 PSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQ 330
P P +FF L GD +KW+ +PF SS G +PE+ S LEV +R +
Sbjct: 283 PDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEI-SPLEV---------LERDK 332
Query: 331 LTELQEPAELVESDGVPKPS 350
+T+L L++ D VP+P+
Sbjct: 333 VTQL-----LLQQDKVPEPA 347
>gi|29171682 interleukin 9 receptor precursor [Homo sapiens]
Length = 521
Score = 68.9 bits (167), Expect = 1e-11
Identities = 75/267 (28%), Positives = 110/267 (41%), Gaps = 42/267 (15%)
Query: 112 FLLAESIKPAPPFNVTVTFS-GQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVS 170
+L +K PP ++ S G ++W PA + L YEL ++ + + W +
Sbjct: 139 YLPRRHVKLDPPSDLQSNISSGHCILTWSIS---PALEPMTTLLSYELAFKKQEEAWEQA 195
Query: 171 PRRKLISVDSRSVSLLPLE-FRKDSSY----ELQVRAGPMPGS-----SYQGTWSEWSDP 220
R I V+ L LE F D + L+V+ + Y G WSEWS P
Sbjct: 196 QHRDHIV----GVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQP 251
Query: 221 VIFQTQSEE----LKEGWNPHLLLLLLLVIVFI-PAFWSLKTHPLWRLWKKIWA--VPSP 273
V FQ + GW + L+ + + ++ P + K P K+I+ VPSP
Sbjct: 252 VCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRV---KRIFYQNVPSP 308
Query: 274 ERFFMPLYKGCSGDFKKWVGAPFTGSSLE-------LGPWSPEVPSTLEVYSCHPPRSPA 326
FF PLY +G+F+ W+GA G L G P V + +C P R P
Sbjct: 309 AMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLTCGPAR-PW 367
Query: 327 KRLQLTELQE------PAELVESDGVP 347
K + L E QE P L D +P
Sbjct: 368 KSVALEEEQEGPGTRLPGNLSSEDVLP 394
>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
Length = 508
Score = 57.0 bits (136), Expect = 4e-08
Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 38/314 (12%)
Query: 19 GCPDLVCYTDYLQTVICILE---MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNAT 75
G +L+C+T+ L+ ++C E + P + ++Q + E K C LH++
Sbjct: 46 GPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWK----LCRLHQAPTARG 101
Query: 76 HATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVT--VTFSGQ 133
+ C + + + +T SG + + AP V SG
Sbjct: 102 AVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161
Query: 134 YNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKD 193
+ W E P + ++YE+ +V +++ ++ R+ +L R
Sbjct: 162 VVLRWLPPPETP----MTSHIRYEVDVSAGNGAGSV---QRVEILEGRTECVLS-NLRGR 213
Query: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
+ Y VRA M S+ G WS WS+PV T S+ L+L+++LV++ + A
Sbjct: 214 TRYTFAVRAR-MAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL 272
Query: 254 SLKTHPLWRLWKKIW-AVPSPERFFMPLYKGCSGDFKKWV--------GAPFTGSSLELG 304
S + L +KIW +PSPE F L+ G+F+ W+ +P T
Sbjct: 273 SHRR----ALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCT------- 321
Query: 305 PWSPEVPSTLEVYS 318
P++ + P++LEV S
Sbjct: 322 PFTEDPPASLEVLS 335
>gi|4557669 interleukin 4 receptor alpha chain isoform a precursor
[Homo sapiens]
Length = 825
Score = 53.1 bits (126), Expect = 6e-07
Identities = 63/254 (24%), Positives = 104/254 (40%), Gaps = 19/254 (7%)
Query: 25 CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84
C +DY+ C +M + L Q L EA +C N A CH+
Sbjct: 34 CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89
Query: 85 VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142
+ ++ D +++++ +G GSF +E +KP P N+TV S ++W + Y
Sbjct: 90 MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147
Query: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202
P L L Y + + DP R ++ S+ + + SY +VRA
Sbjct: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203
Query: 203 GPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWR 262
Y TWSEWS + +E + HLLL + + + I A L + +
Sbjct: 204 W---AQCYNTTWSEWSPSTKWH---NSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITK 257
Query: 263 LWKKIW-AVPSPER 275
+ K+ W +P+P R
Sbjct: 258 IKKEWWDQIPNPAR 271
>gi|28610151 interleukin 7 receptor precursor [Homo sapiens]
Length = 459
Score = 52.8 bits (125), Expect = 8e-07
Identities = 38/169 (22%), Positives = 78/169 (46%), Gaps = 12/169 (7%)
Query: 97 NITDQSGNYSQECGSFLLAESIKPAPPFNVTVTF---SGQYNISWRSDYEDPAFYMLKGK 153
NI + G S C L +KP PF+++V + + + +++ + + + +
Sbjct: 106 NICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKV--- 162
Query: 154 LQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGT 213
L +++ YR D + +++ S ++LL + + + YE++VR+ +P ++G
Sbjct: 163 LMHDVAYRQEKD----ENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRS--IPDHYFKGF 216
Query: 214 WSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWR 262
WSEWS F+T G +LL + ++ F A + LW+
Sbjct: 217 WSEWSPSYYFRTPEINNSSGEMDPILLTISILSFFSVALLVILACVLWK 265
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query: 118 IKPAPPF--NVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKL 175
+KP PP ++ +T G ISW S P LQY+++Y + + K+
Sbjct: 235 VKPDPPLGLHMEITDDGNLKISWSSPPLVPF------PLQYQVKY-SENSTTVIREADKI 287
Query: 176 ISVDSRSV-SLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
+S S V S+LP SSYE+QVR + G G WS+WS P +F TQ
Sbjct: 288 VSATSLLVDSILP-----GSSYEVQVRGKRLDGP---GIWSDWSTPRVFTTQ 331
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 44/230 (19%)
Query: 79 YTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS---GQYN 135
Y C ++ + I G+ L +KP PP +V + G
Sbjct: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555
Query: 136 ISWRSDYEDPAFYMLKGKLQYELQYRNRGDP--WAVSPRRKLISVDSRSVSLLPLEFRKD 193
ISW E P F + LQ++++Y G W + ++ S+SVSL +
Sbjct: 556 ISW----EKPVFP--ENNLQFQIRYGLSGKEVQWKMY---EVYDAKSKSVSLPVPDLC-- 604
Query: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
+ Y +QVR + G Y WS WS+P + +++ + V + P FW
Sbjct: 605 AVYAVQVRCKRLDGLGY---WSNWSNPA---------------YTVVMDIKVPMRGPEFW 646
Query: 254 SL-------KTHPLWRLWKKIW---AVPSPERFFMPLYKGCSGDFKKWVG 293
+ K + LWK + ++ S +R+ + + C+G + + VG
Sbjct: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVG 696
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query: 118 IKPAPPF--NVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKL 175
+KP PP ++ +T G ISW S P LQY+++Y + + K+
Sbjct: 235 VKPDPPLGLHMEITDDGNLKISWSSPPLVPF------PLQYQVKY-SENSTTVIREADKI 287
Query: 176 ISVDSRSV-SLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
+S S V S+LP SSYE+QVR + G G WS+WS P +F TQ
Sbjct: 288 VSATSLLVDSILP-----GSSYEVQVRGKRLDGP---GIWSDWSTPRVFTTQ 331
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 44/230 (19%)
Query: 79 YTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS---GQYN 135
Y C ++ + I G+ L +KP PP +V + G
Sbjct: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555
Query: 136 ISWRSDYEDPAFYMLKGKLQYELQYRNRGDP--WAVSPRRKLISVDSRSVSLLPLEFRKD 193
ISW E P F + LQ++++Y G W + ++ S+SVSL +
Sbjct: 556 ISW----EKPVFP--ENNLQFQIRYGLSGKEVQWKMY---EVYDAKSKSVSLPVPDLC-- 604
Query: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
+ Y +QVR + G Y WS WS+P + +++ + V + P FW
Sbjct: 605 AVYAVQVRCKRLDGLGY---WSNWSNPA---------------YTVVMDIKVPMRGPEFW 646
Query: 254 SL-------KTHPLWRLWKKIW---AVPSPERFFMPLYKGCSGDFKKWVG 293
+ K + LWK + ++ S +R+ + + C+G + + VG
Sbjct: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVG 696
>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
Length = 1165
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query: 118 IKPAPPF--NVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKL 175
+KP PP ++ +T G ISW S P LQY+++Y + + K+
Sbjct: 235 VKPDPPLGLHMEITDDGNLKISWSSPPLVPF------PLQYQVKY-SENSTTVIREADKI 287
Query: 176 ISVDSRSV-SLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
+S S V S+LP SSYE+QVR + G G WS+WS P +F TQ
Sbjct: 288 VSATSLLVDSILP-----GSSYEVQVRGKRLDGP---GIWSDWSTPRVFTTQ 331
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 44/230 (19%)
Query: 79 YTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS---GQYN 135
Y C ++ + I G+ L +KP PP +V + G
Sbjct: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555
Query: 136 ISWRSDYEDPAFYMLKGKLQYELQYRNRGDP--WAVSPRRKLISVDSRSVSLLPLEFRKD 193
ISW E P F + LQ++++Y G W + ++ S+SVSL +
Sbjct: 556 ISW----EKPVFP--ENNLQFQIRYGLSGKEVQWKMY---EVYDAKSKSVSLPVPDLC-- 604
Query: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
+ Y +QVR + G Y WS WS+P + +++ + V + P FW
Sbjct: 605 AVYAVQVRCKRLDGLGY---WSNWSNPA---------------YTVVMDIKVPMRGPEFW 646
Query: 254 SL-------KTHPLWRLWKKIW---AVPSPERFFMPLYKGCSGDFKKWVG 293
+ K + LWK + ++ S +R+ + + C+G + + VG
Sbjct: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVG 696
>gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo
sapiens]
Length = 371
Score = 51.2 bits (121), Expect = 2e-06
Identities = 91/377 (24%), Positives = 146/377 (38%), Gaps = 66/377 (17%)
Query: 5 WAAPLLLLLLQGGW----------GCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQ 54
W A + LL GGW G + Y + L+TV + LT ++
Sbjct: 8 WGAAVFLL---GGWMALGQGGAAEGVQIQIIYFN-LETVQVTWNASKYSRTNLTFHYRFN 63
Query: 55 YEELKDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLL 114
+E D+ T+ L T C +D DDI +I ++G + S +
Sbjct: 64 GDEAYDQCTNYLLQEGH------TSGCLLDAEQ--RDDILYFSI--RNGTHPVFTASRWM 113
Query: 115 AESIKPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLK-GKLQYELQYRNRGDPWAVSPRR 173
+KP+ P +V SW D L G L YE+QYR+ D S +
Sbjct: 114 VYYLKPSSPKHV--------RFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQSKQE 165
Query: 174 KLISVDSRSVSLLPLEFRKDSSYELQVRA-----GPMPGSSYQGTWSE---WSDPVIFQT 225
++ +V++ L+ K S+ ++V+A GP +Y WSE W I +
Sbjct: 166 -----NTCNVTIEGLDAEKCYSFWVRVKAMEDVYGP---DTYPSDWSEVTCWQRGEI-RD 216
Query: 226 QSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWRLWKK----IWAVPSPERFFMPLY 281
E P L +L+ + I SL LW+LW+ I +VP P+ F L+
Sbjct: 217 ACAETPTPPKPKLSKFILISSLAILLMVSLLLLSLWKLWRVKKFLIPSVPDPKSIFPGLF 276
Query: 282 KGCSGDFKKWVG--------APFTGSSLELGPWSPEVPSTLEVYSCHP----PRSPAKRL 329
+ G+F++W+ G+ E GP P V + + P P++ K
Sbjct: 277 EIHQGNFQEWITDTQNVAHLHKMAGAEQESGPEEPLVVQLAKTEAESPRMLDPQTEEKEA 336
Query: 330 QLTELQEPAELVESDGV 346
LQ P + ++ V
Sbjct: 337 SGGSLQLPHQPLQGGDV 353
>gi|4559408 colony stimulating factor 2 receptor, beta precursor
[Homo sapiens]
Length = 897
Score = 49.7 bits (117), Expect = 7e-06
Identities = 69/272 (25%), Positives = 105/272 (38%), Gaps = 53/272 (19%)
Query: 117 SIKPAPPFNVTVTFSGQ-YNISW-----RSDYEDPAFYMLKGKLQYELQYRNRGDPWAVS 170
+I+ APP ++ VT G Y++ W R ++ D F E+QYR W S
Sbjct: 337 NIQMAPP-SLNVTKDGDSYSLRWETMKMRYEHIDHTF---------EIQYRKDTATWKDS 386
Query: 171 PRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEEL 230
L + S ++ L R Y +VR + Y G WSEWS+ + T+S +
Sbjct: 387 KTETLQNAHSMALPALEPSTR----YWARVRVRTSR-TGYNGIWSEWSEARSWDTES--V 439
Query: 231 KEGWNPHLLLLLLLVIVFIP-AFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFK 289
W L+++ L + V + F + + L R W++ PS F +G +
Sbjct: 440 LPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPNPSKSHLFQ------NGSAE 493
Query: 290 KW----VGAPFTGSSLELGPWS---PEV--------------PSTLE--VYSCHPPRSPA 326
W + A +GS GPW PE+ P T+E + C PP P
Sbjct: 494 LWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPD 553
Query: 327 KRLQLTELQEPAELVESDGVPKPSFWPTAQNS 358
++L G P S P Q S
Sbjct: 554 TTPAASDLPTEQPPSPQPGPPAASHTPEKQAS 585
Score = 41.6 bits (96), Expect = 0.002
Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 114 LAESIKPAPPFNVTV-TFSGQYNISWRSDYEDPAFYMLK-GKLQYELQYRNRGDPWAVSP 171
L + ++P P ++ + T + ++W P + L G L++E+ Y+ D W +
Sbjct: 127 LTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQDSWEDAA 186
Query: 172 RRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
++ ++ +L P S+Y +VR PGS G S+WS V + +Q
Sbjct: 187 ---ILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQ 238
>gi|4885491 myeloproliferative leukemia virus oncogene precursor
[Homo sapiens]
Length = 635
Score = 49.3 bits (116), Expect = 9e-06
Identities = 71/282 (25%), Positives = 104/282 (36%), Gaps = 44/282 (15%)
Query: 14 LQGGWGCPDLVCYTDYLQTVICI-LEMWNLHPSTLTLTWQDQYEELKD------EATSCS 66
L G WG L D + + L+ + L +T WQ Q A C
Sbjct: 265 LGGSWGSWSLPVTVDLPGDAVALGLQCFTLDLKNVTCQWQQQDHASSQGFFYHSRARCCP 324
Query: 67 LHR--------SAHNATHATYTCHMDVFHFMA--DDIFS--VNITDQSGNYSQECGS-FL 113
R T HF + D I V +T G GS F
Sbjct: 325 RDRYPIWENCEEEEKTNPGLQTPQFSRCHFKSRNDSIIHILVEVTTAPGTVHSYLGSPFW 384
Query: 114 LAESIK-PAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRG-DPWAVSP 171
+ ++++ P P + SG + W + P+ + + + Y+L+Y G W V
Sbjct: 385 IHQAVRLPTPNLHWREISSGHLELEW----QHPSSWAAQ-ETCYQLRYTGEGHQDWKVLE 439
Query: 172 RRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELK 231
+ +R +L E R S Y LQ+RA + G +YQG WS WSDP +T +E
Sbjct: 440 P----PLGARGGTL---ELRPRSRYRLQLRAR-LNGPTYQGPWSSWSDPTRVETATE--- 488
Query: 232 EGWNP-----HLLLLLLLVIVFIPAFWSLKTHPLWRLWKKIW 268
W HL+L L V+ + W H RL +W
Sbjct: 489 TAWISLVTALHLVLGLSAVLGLLLLRWQFPAH-YRRLRHALW 529
Score = 33.9 bits (76), Expect = 0.39
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 166 PWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPV 221
P SP R+ ++ + S L + +SY LQ+R+ P G S G+W WS PV
Sbjct: 222 PKQTSPSREASALTAEGGSCLISGLQPGNSYWLQLRSEP-DGISLGGSWGSWSLPV 276
>gi|56788411 interleukin 4 receptor alpha chain isoform b precursor
[Homo sapiens]
Length = 227
Score = 45.4 bits (106), Expect = 1e-04
Identities = 50/196 (25%), Positives = 79/196 (40%), Gaps = 15/196 (7%)
Query: 25 CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84
C +DY+ C +M + L Q L EA +C N A CH+
Sbjct: 34 CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89
Query: 85 VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142
+ ++ D +++++ +G GSF +E +KP P N+TV S ++W + Y
Sbjct: 90 MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147
Query: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202
P L L Y + + DP R ++ S+ + + SY +VRA
Sbjct: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203
Query: 203 GPMPGSSYQGTWSEWS 218
Y TWSEWS
Sbjct: 204 W---AQCYNTTWSEWS 216
>gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo
sapiens]
Length = 259
Score = 44.3 bits (103), Expect = 3e-04
Identities = 51/188 (27%), Positives = 82/188 (43%), Gaps = 30/188 (15%)
Query: 118 IKPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLK-GKLQYELQYRNRGDPWAVSPRRKLI 176
+KP+ P +V SW D L G L YE+QYR+ D S +
Sbjct: 5 LKPSSPKHV--------RFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQSKQE--- 53
Query: 177 SVDSRSVSLLPLEFRKDSSYELQVRA-----GPMPGSSYQGTWSE---WSDPVIFQTQSE 228
++ +V++ L+ K S+ ++V+A GP +Y WSE W I +
Sbjct: 54 --NTCNVTIEGLDAEKCYSFWVRVKAMEDVYGP---DTYPSDWSEVTCWQRGEI-RDACA 107
Query: 229 ELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWRLWKK----IWAVPSPERFFMPLYKGC 284
E P L +L+ + I SL LW+LW+ I +VP P+ F L++
Sbjct: 108 ETPTPPKPKLSKFILISSLAILLMVSLLLLSLWKLWRVRKFLIPSVPDPKSIFPGLFEIH 167
Query: 285 SGDFKKWV 292
G+F++W+
Sbjct: 168 QGNFQEWI 175
>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
Length = 369
Score = 43.5 bits (101), Expect = 5e-04
Identities = 57/234 (24%), Positives = 96/234 (41%), Gaps = 34/234 (14%)
Query: 21 PDLVCYTDYLQTVICILEMWNL----HPSTLTLTWQDQYEELKDEATSCSLHRSAHNATH 76
P++ C+ ++ + C WN P+ LTL + + + D+ CS + + T
Sbjct: 58 PEVQCFVFNVEYMNCT---WNSSSEPQPTNLTLHYWYKNSD-NDKVQKCSHYLFSEEITS 113
Query: 77 ATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQY 134
C + F V + D Q L + P P N+T+ Q
Sbjct: 114 G---CQLQKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQL 170
Query: 135 NISWRSDYEDPAFYMLKGKLQYELQYRNRGD-PWAVSPRRKLISVDSRSVSLLP-LEFRK 192
++W + + L L++ +QYR D W SVD R LP ++ +K
Sbjct: 171 ELNWNNRF-------LNHCLEHLVQYRTDWDHSWTEQ------SVDYRHKFSLPSVDGQK 217
Query: 193 DSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVI 246
++ ++ R P+ GS+ WSEWS P+ + + + KE NP L L +VI
Sbjct: 218 RYTFRVRSRFNPLCGSAQH--WSEWSHPIHWGSNTS--KE--NPFLFALEAVVI 265
>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 18/162 (11%)
Query: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
PP NVT G + +I W E P YE++ N R + ++
Sbjct: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
+ S Y++QVRA G WSEWS P+ + W ++
Sbjct: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREW---FVI 345
Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIW-AVPSPERFFMPLY 281
+++ I FI SL + LW K++ +P+P+ L+
Sbjct: 346 VIMATICFILLILSL-ICKICHLWIKLFPPIPAPKSNIKDLF 386
>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 18/162 (11%)
Query: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
PP NVT G + +I W E P YE++ N R + ++
Sbjct: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
+ S Y++QVRA G WSEWS P+ + W ++
Sbjct: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREW---FVI 345
Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIW-AVPSPERFFMPLY 281
+++ I FI SL + LW K++ +P+P+ L+
Sbjct: 346 VIMATICFILLILSL-ICKICHLWIKLFPPIPAPKSNIKDLF 386
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 40.8 bits (94), Expect = 0.003
Identities = 42/164 (25%), Positives = 70/164 (42%), Gaps = 19/164 (11%)
Query: 75 THATYTCHM--DVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSG 132
T ++CH+ D+ F +I+ V T++ G+ + + + + + PP +V V+ G
Sbjct: 189 TVGPHSCHIPKDLALFTPYEIW-VEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVG 247
Query: 133 ----QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGD-PWAVSPRRKLISVDSRSVSLLP 187
Q ++ W S PA + +Y+++YR W K++ S S
Sbjct: 248 GLEDQLSVRWVSP---PALKDFLFQAKYQIRYRVEDSVDW------KVVDDVSNQTSCRL 298
Query: 188 LEFRKDSSYELQVRAGPMP--GSSYQGTWSEWSDPVIFQTQSEE 229
+ + Y +QVR P GS G WSEWS P T E
Sbjct: 299 AGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSE 342
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/177 (20%), Positives = 72/177 (40%), Gaps = 20/177 (11%)
Query: 59 KDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESI 118
+D TSC++ S Y +++V+ V + G + + +F +
Sbjct: 176 RDTPTSCTVDYST------VYFVNIEVW---------VEAENALGKVTSDHINFDPVYKV 220
Query: 119 KPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNR-GDPWAVSPRRKLIS 177
KP PP N++V S + + + + +P+ + L+Y +QYR + W+ P S
Sbjct: 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTAS 279
Query: 178 VDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGW 234
S S + + + Y ++R G Y WSE + + ++ + + W
Sbjct: 280 TRS---SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 37.4 bits (85), Expect = 0.035
Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 23/162 (14%)
Query: 59 KDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESI 118
+D TSC++ S Y +++V+ V + G + + +F +
Sbjct: 176 RDTPTSCTVDYST------VYFVNIEVW---------VEAENALGKVTSDHINFDPVYKV 220
Query: 119 KPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNR-GDPWAVSPRRKLIS 177
KP PP N++V S + + + + +P+ + L+Y +QYR + W+ P S
Sbjct: 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTAS 279
Query: 178 VDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSD 219
S S + + + Y ++R G Y WS+WS+
Sbjct: 280 TRS---SFTVQDLKPFTEYVFRIRCMKEDGKGY---WSDWSE 315
>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
sapiens]
Length = 468
Score = 37.0 bits (84), Expect = 0.046
Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 19/132 (14%)
Query: 93 IFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRS-DYEDP-----A 146
I S+ + G+ + +F ++P PP N+TVT + N W S ++DP +
Sbjct: 189 IVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVAR-NPRWLSVTWQDPHSWNSS 247
Query: 147 FYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMP 206
FY L+ +L+Y + W V + + L + +Q+RA
Sbjct: 248 FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL---------RHVVQLRAQEEF 298
Query: 207 GSSYQGTWSEWS 218
G QG WSEWS
Sbjct: 299 G---QGEWSEWS 307
>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
sapiens]
Length = 365
Score = 37.0 bits (84), Expect = 0.046
Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 19/132 (14%)
Query: 93 IFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRS-DYEDP-----A 146
I S+ + G+ + +F ++P PP N+TVT + N W S ++DP +
Sbjct: 189 IVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVAR-NPRWLSVTWQDPHSWNSS 247
Query: 147 FYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMP 206
FY L+ +L+Y + W V + + L + +Q+RA
Sbjct: 248 FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL---------RHVVQLRAQEEF 298
Query: 207 GSSYQGTWSEWS 218
G QG WSEWS
Sbjct: 299 G---QGEWSEWS 307
>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
Length = 1669
Score = 36.6 bits (83), Expect = 0.060
Identities = 47/163 (28%), Positives = 62/163 (38%), Gaps = 31/163 (19%)
Query: 386 GPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSL 445
GP S D G P + G PG P D G + + G+PGL GP GS
Sbjct: 960 GPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISG------TPGAPGLPGPKGS- 1012
Query: 446 LDRLKPPLADGEDWAGGLPWGGRSPG-------GVSESEAGSP---LAGLDMDTFDSGFV 495
+ + P GE G+P SPG + +AG P + GL + D G
Sbjct: 1013 VGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIA 1072
Query: 496 GSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
G SPG++G S + IP SPG + S
Sbjct: 1073 GFP---------GSPGEKGEKGS-----IGIPGMPGSPGLKGS 1101
Score = 31.6 bits (70), Expect = 1.9
Identities = 35/121 (28%), Positives = 43/121 (35%), Gaps = 4/121 (3%)
Query: 398 GYPALDLDAGLEPSPGL--EDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLAD 455
G+P D G PG P+ D G G S G PG G G ++ PP A+
Sbjct: 592 GFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAE 651
Query: 456 GEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGP 515
G + G P G + G + L G G P D PGD GP
Sbjct: 652 GLPGSPGFP-GPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVD-GLPGDMGP 709
Query: 516 P 516
P
Sbjct: 710 P 710
Score = 30.4 bits (67), Expect = 4.3
Identities = 40/151 (26%), Positives = 49/151 (32%), Gaps = 41/151 (27%)
Query: 396 DDGYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSA----GSPGLGGPLGSLLDRLKP 451
+ GYP L G + G P G V+ G + G PG GP G
Sbjct: 306 EPGYPGLIGRQGPQGEKGEAGPPGPPGI-VIGTGPLGEKGERGYPGTPGPRGE------- 357
Query: 452 PLADGEDWAGGLPWGGRSPGGVSESEAGSP-LAGLDMDTFDSGFVGSDCSSP-------- 502
G GLP PG +AG+P G + D GF G+ P
Sbjct: 358 ---PGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPG 414
Query: 503 -----------------VECDFTSPGDEGPP 516
VEC PGD+GPP
Sbjct: 415 PPGSPGPPGQPGYTNGIVECQPGPPGDQGPP 445
>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
Length = 862
Score = 35.8 bits (81), Expect = 0.10
Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 21/138 (15%)
Query: 96 VNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS----GQYNISWRSDYEDPAFYMLK 151
V + G+ S +F + ++P PP+++ + F + + WR D +L
Sbjct: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLN 255
Query: 152 GKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQ 211
L+YR S +++V L+ + + YE Q+ + Y+
Sbjct: 256 -----RLRYRPSN-----SRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKL---HLYK 302
Query: 212 GTWSEWSDPVIFQTQSEE 229
G+WS+WS+ + QT EE
Sbjct: 303 GSWSDWSESLRAQTPEEE 320
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 35.8 bits (81), Expect = 0.10
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 14/133 (10%)
Query: 397 DGYPALDLDAGL---EPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSL-------- 445
DG P L + G+ E PGL+ P G G+PGL GP G
Sbjct: 2149 DGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGE 2208
Query: 446 LDRLKPPLAD--GEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPV 503
PP G A GLP G P G+ + L G +T G G D +S
Sbjct: 2209 PGETGPPGRGLTGPTGAVGLP-GPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGK 2267
Query: 504 ECDFTSPGDEGPP 516
+ D SPG G P
Sbjct: 2268 DGDRGSPGVPGSP 2280
Score = 33.5 bits (75), Expect = 0.50
Identities = 41/144 (28%), Positives = 52/144 (36%), Gaps = 20/144 (13%)
Query: 396 DDGYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKP--PL 453
D G P LD +GL+ PG P G + G PGL G G P P
Sbjct: 1771 DRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPG 1830
Query: 454 ADGEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECDFTSP--- 510
GED GL PG E G + DSG G + + + +P
Sbjct: 1831 KPGEDGKPGLNGKNGEPGDPGED-------GRKGEKGDSGASGREGRDGPKGERGAPGIL 1883
Query: 511 GDEGPPRSYLRQWVVIPPPLSSPG 534
G +GPP +P P+ PG
Sbjct: 1884 GPQGPPG--------LPGPVGPPG 1899
Score = 30.4 bits (67), Expect = 4.3
Identities = 27/85 (31%), Positives = 32/85 (37%), Gaps = 18/85 (21%)
Query: 434 GSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGV--SESEAGSPLAGLDMDTFD 491
G PG+ GP G DR PP DG G P G P G + +AG P
Sbjct: 1758 GDPGVRGPAGEKGDR-GPPGLDGRSGLDGKP-GAAGPSGPNGAAGKAGDP---------- 1805
Query: 492 SGFVGSDCSSPVECDFTSPGDEGPP 516
G D + + PG GPP
Sbjct: 1806 ----GRDGLPGLRGEQGLPGPSGPP 1826
Score = 30.4 bits (67), Expect = 4.3
Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 14/117 (11%)
Query: 405 DAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPP----LADGEDWA 460
D+G + PG E P+ G L G PG GP G L PP LA GE
Sbjct: 1983 DSGEQGPPGKEGPIGFPGERGLKG---DRGDPGPQGPPGLALGERGPPGPSGLA-GEPGK 2038
Query: 461 GGLPWGGRSPGGVSESEAGSP-LAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPP 516
G+P GGV EAG P G + + G G D + +PG GPP
Sbjct: 2039 PGIPGLPGRAGGV--GEAGRPGERGERGEKGERGEQGRDGPPGLP---GTPGPPGPP 2090
Score = 30.0 bits (66), Expect = 5.6
Identities = 30/83 (36%), Positives = 35/83 (42%), Gaps = 12/83 (14%)
Query: 434 GSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSG 493
GSPG GP+G K D ED A GLP SPG + G P G D G
Sbjct: 1430 GSPGPQGPVGP--PGKKGEKGDSEDGAPGLPGQPGSPG--EQGPRGPP--GAIGPKGDRG 1483
Query: 494 FVGSDCSSPVECDFTSPGDEGPP 516
F G P+ + G+ GPP
Sbjct: 1484 FPG-----PLG-EAGEKGERGPP 1500
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 35.0 bits (79), Expect = 0.17
Identities = 47/144 (32%), Positives = 52/144 (36%), Gaps = 28/144 (19%)
Query: 398 GYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSA-GSPGLGGPLGSLLDRLKPPLADG 456
G+P GL+ PG P + G T G V G PG GP G P A G
Sbjct: 1219 GFPGPPGPVGLQGLPG---PPGEKGET----GDVGQMGPPGPPGPRG-------PSGAPG 1264
Query: 457 EDWAGGLPWGGRSPGGVSE----SEAGSP-LAGLDMDTFDSGFVGSDCSSPVECDFTSPG 511
D G P G +PG V E EAG P L G G G S PG
Sbjct: 1265 ADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPG 1324
Query: 512 DEGPPRSYLRQWVVIPPPLSSPGP 535
+GPP P SPGP
Sbjct: 1325 PKGPPGD--------DGPKGSPGP 1340
>gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [Homo
sapiens]
Length = 333
Score = 35.0 bits (79), Expect = 0.17
Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 13/101 (12%)
Query: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
PP NVT G + +I W E P YE++ N R + ++
Sbjct: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPV 221
+ S Y++QVRA G WSEWS P+
Sbjct: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPI 329
>gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [Homo
sapiens]
Length = 335
Score = 35.0 bits (79), Expect = 0.17
Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 13/101 (12%)
Query: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
PP NVT G + +I W E P YE++ N R + ++
Sbjct: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPV 221
+ S Y++QVRA G WSEWS P+
Sbjct: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPI 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.137 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,252,803
Number of Sequences: 37866
Number of extensions: 1537894
Number of successful extensions: 4439
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 4246
Number of HSP's gapped (non-prelim): 271
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.