Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 31083180

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
         (538 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31083174 interleukin 21 receptor precursor [Homo sapiens]         1144   0.0  
gi|11141869 interleukin 21 receptor precursor [Homo sapiens]         1144   0.0  
gi|31083180 interleukin 21 receptor precursor [Homo sapiens]         1144   0.0  
gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]        81   3e-15
gi|29171682 interleukin 9 receptor precursor [Homo sapiens]            69   1e-11
gi|4503591 erythropoietin receptor precursor [Homo sapiens]            57   4e-08
gi|4557669 interleukin 4 receptor alpha chain isoform a precurso...    53   6e-07
gi|28610151 interleukin 7 receptor precursor [Homo sapiens]            53   8e-07
gi|51093381 leptin receptor isoform 3 [Homo sapiens]                   51   2e-06
gi|51093379 leptin receptor isoform 2 [Homo sapiens]                   51   2e-06
gi|40254464 leptin receptor isoform 1 [Homo sapiens]                   51   2e-06
gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo sapi...    51   2e-06
gi|4559408 colony stimulating factor 2 receptor, beta precursor ...    50   7e-06
gi|4885491 myeloproliferative leukemia virus oncogene precursor ...    49   9e-06
gi|56788411 interleukin 4 receptor alpha chain isoform b precurs...    45   1e-04
gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo sapi...    44   3e-04
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]      44   5e-04
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H...    42   0.001
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H...    42   0.001
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]              41   0.003
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ...    40   0.007
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ...    37   0.035
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi...    37   0.046
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap...    37   0.046
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     37   0.060
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]    36   0.10 
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          36   0.10 
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       35   0.17 
gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [H...    35   0.17 
gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [H...    35   0.17 

>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 1144 bits (2958), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60
           MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
Sbjct: 1   MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60

Query: 61  EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120
           EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
Sbjct: 61  EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120

Query: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
           APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
Sbjct: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180

Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
           RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240

Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300
           LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
Sbjct: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300

Query: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360
           LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
Sbjct: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360

Query: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420
           SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
Sbjct: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420

Query: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480
           AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
Sbjct: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480

Query: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
           PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
Sbjct: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538


>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 1144 bits (2958), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60
           MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
Sbjct: 1   MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60

Query: 61  EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120
           EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
Sbjct: 61  EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120

Query: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
           APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
Sbjct: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180

Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
           RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240

Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300
           LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
Sbjct: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300

Query: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360
           LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
Sbjct: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360

Query: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420
           SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
Sbjct: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420

Query: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480
           AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
Sbjct: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480

Query: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
           PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
Sbjct: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538


>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 1144 bits (2958), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60
           MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
Sbjct: 1   MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD 60

Query: 61  EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120
           EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
Sbjct: 61  EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP 120

Query: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
           APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
Sbjct: 121 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180

Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
           RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240

Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300
           LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
Sbjct: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS 300

Query: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360
           LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
Sbjct: 301 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG 360

Query: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420
           SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
Sbjct: 361 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD 420

Query: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480
           AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
Sbjct: 421 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS 480

Query: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
           PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
Sbjct: 481 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538


>gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]
          Length = 551

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 99/380 (26%), Positives = 158/380 (41%), Gaps = 74/380 (19%)

Query: 5   WAAPLLLLLLQ--GGW------GCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYE 56
           W  PLL+LLL     W      G     C+ +    + C+   W+            Q  
Sbjct: 8   WRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCV---WS------------QDG 52

Query: 57  ELKDEATSCSLH----RSAHNAT-------HATYTCHM-----DVFHFMADDIFSVNITD 100
            L+D  TSC +H    R   N T        A++ C++     D       DI ++ +  
Sbjct: 53  ALQD--TSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLC 110

Query: 101 QSGNYSQECG--SFLLAESIKPAPPFNVTVTF--SGQYNISWRSDYEDPAFYMLKGKLQY 156
           + G   +      F   E+++   P ++ V    + + NISW       A +  +  L++
Sbjct: 111 REGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ---ASHYFERHLEF 167

Query: 157 ELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSE 216
           E +  + G  W  +P   L+++  +   +       D+ YE QVR  P+ G     TWS 
Sbjct: 168 EARTLSPGHTWEEAP---LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT--TWSP 222

Query: 217 WSDPVIFQTQSEELKEG---WNPHLLLLLLLVIVFIPAFWSLKTHPLWRLW-KKIWA--V 270
           WS P+ F+T+   L +    W  HLL+ L     FI   + L        W KK+     
Sbjct: 223 WSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNT 282

Query: 271 PSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQ 330
           P P +FF  L     GD +KW+ +PF  SS   G  +PE+ S LEV          +R +
Sbjct: 283 PDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEI-SPLEV---------LERDK 332

Query: 331 LTELQEPAELVESDGVPKPS 350
           +T+L     L++ D VP+P+
Sbjct: 333 VTQL-----LLQQDKVPEPA 347


>gi|29171682 interleukin 9 receptor precursor [Homo sapiens]
          Length = 521

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 75/267 (28%), Positives = 110/267 (41%), Gaps = 42/267 (15%)

Query: 112 FLLAESIKPAPPFNVTVTFS-GQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVS 170
           +L    +K  PP ++    S G   ++W      PA   +   L YEL ++ + + W  +
Sbjct: 139 YLPRRHVKLDPPSDLQSNISSGHCILTWSIS---PALEPMTTLLSYELAFKKQEEAWEQA 195

Query: 171 PRRKLISVDSRSVSLLPLE-FRKDSSY----ELQVRAGPMPGS-----SYQGTWSEWSDP 220
             R  I      V+ L LE F  D  +     L+V+   +         Y G WSEWS P
Sbjct: 196 QHRDHIV----GVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQP 251

Query: 221 VIFQTQSEE----LKEGWNPHLLLLLLLVIVFI-PAFWSLKTHPLWRLWKKIWA--VPSP 273
           V FQ    +       GW  + L+ + + ++   P +   K  P     K+I+   VPSP
Sbjct: 252 VCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRV---KRIFYQNVPSP 308

Query: 274 ERFFMPLYKGCSGDFKKWVGAPFTGSSLE-------LGPWSPEVPSTLEVYSCHPPRSPA 326
             FF PLY   +G+F+ W+GA   G  L         G   P V     + +C P R P 
Sbjct: 309 AMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLTCGPAR-PW 367

Query: 327 KRLQLTELQE------PAELVESDGVP 347
           K + L E QE      P  L   D +P
Sbjct: 368 KSVALEEEQEGPGTRLPGNLSSEDVLP 394


>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
          Length = 508

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 38/314 (12%)

Query: 19  GCPDLVCYTDYLQTVICILE---MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNAT 75
           G  +L+C+T+ L+ ++C  E      + P   + ++Q + E  K     C LH++     
Sbjct: 46  GPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWK----LCRLHQAPTARG 101

Query: 76  HATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVT--VTFSGQ 133
              + C +      +     + +T  SG         +    +  AP   V      SG 
Sbjct: 102 AVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161

Query: 134 YNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKD 193
             + W    E P    +   ++YE+         +V   +++  ++ R+  +L    R  
Sbjct: 162 VVLRWLPPPETP----MTSHIRYEVDVSAGNGAGSV---QRVEILEGRTECVLS-NLRGR 213

Query: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
           + Y   VRA  M   S+ G WS WS+PV   T S+         L+L+++LV++ + A  
Sbjct: 214 TRYTFAVRAR-MAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL 272

Query: 254 SLKTHPLWRLWKKIW-AVPSPERFFMPLYKGCSGDFKKWV--------GAPFTGSSLELG 304
           S +      L +KIW  +PSPE  F  L+    G+F+ W+         +P T       
Sbjct: 273 SHRR----ALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCT------- 321

Query: 305 PWSPEVPSTLEVYS 318
           P++ + P++LEV S
Sbjct: 322 PFTEDPPASLEVLS 335


>gi|4557669 interleukin 4 receptor alpha chain isoform a precursor
           [Homo sapiens]
          Length = 825

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 63/254 (24%), Positives = 104/254 (40%), Gaps = 19/254 (7%)

Query: 25  CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84
           C +DY+    C  +M      +  L    Q   L  EA +C       N   A   CH+ 
Sbjct: 34  CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89

Query: 85  VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142
           +   ++ D +++++   +G      GSF  +E +KP  P N+TV    S    ++W + Y
Sbjct: 90  MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147

Query: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202
             P    L   L Y +   +  DP     R   ++    S+ +     +   SY  +VRA
Sbjct: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203

Query: 203 GPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWR 262
                  Y  TWSEWS    +       +E +  HLLL + +  + I A   L    + +
Sbjct: 204 W---AQCYNTTWSEWSPSTKWH---NSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITK 257

Query: 263 LWKKIW-AVPSPER 275
           + K+ W  +P+P R
Sbjct: 258 IKKEWWDQIPNPAR 271


>gi|28610151 interleukin 7 receptor precursor [Homo sapiens]
          Length = 459

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 38/169 (22%), Positives = 78/169 (46%), Gaps = 12/169 (7%)

Query: 97  NITDQSGNYSQECGSFLLAESIKPAPPFNVTVTF---SGQYNISWRSDYEDPAFYMLKGK 153
           NI  + G  S  C    L   +KP  PF+++V +   +  + +++ + +    +  +   
Sbjct: 106 NICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKV--- 162

Query: 154 LQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGT 213
           L +++ YR   D      +   +++ S  ++LL  + +  + YE++VR+  +P   ++G 
Sbjct: 163 LMHDVAYRQEKD----ENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRS--IPDHYFKGF 216

Query: 214 WSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWR 262
           WSEWS    F+T       G    +LL + ++  F  A   +    LW+
Sbjct: 217 WSEWSPSYYFRTPEINNSSGEMDPILLTISILSFFSVALLVILACVLWK 265


>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
          Length = 958

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)

Query: 118 IKPAPPF--NVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKL 175
           +KP PP   ++ +T  G   ISW S    P        LQY+++Y +      +    K+
Sbjct: 235 VKPDPPLGLHMEITDDGNLKISWSSPPLVPF------PLQYQVKY-SENSTTVIREADKI 287

Query: 176 ISVDSRSV-SLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
           +S  S  V S+LP      SSYE+QVR   + G    G WS+WS P +F TQ
Sbjct: 288 VSATSLLVDSILP-----GSSYEVQVRGKRLDGP---GIWSDWSTPRVFTTQ 331



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 44/230 (19%)

Query: 79  YTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS---GQYN 135
           Y C       ++     + I    G+        L    +KP PP +V    +   G   
Sbjct: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555

Query: 136 ISWRSDYEDPAFYMLKGKLQYELQYRNRGDP--WAVSPRRKLISVDSRSVSLLPLEFRKD 193
           ISW    E P F   +  LQ++++Y   G    W +    ++    S+SVSL   +    
Sbjct: 556 ISW----EKPVFP--ENNLQFQIRYGLSGKEVQWKMY---EVYDAKSKSVSLPVPDLC-- 604

Query: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
           + Y +QVR   + G  Y   WS WS+P                + +++ + V +  P FW
Sbjct: 605 AVYAVQVRCKRLDGLGY---WSNWSNPA---------------YTVVMDIKVPMRGPEFW 646

Query: 254 SL-------KTHPLWRLWKKIW---AVPSPERFFMPLYKGCSGDFKKWVG 293
            +       K   +  LWK +    ++ S +R+ +  +  C+G + + VG
Sbjct: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVG 696


>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
          Length = 896

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)

Query: 118 IKPAPPF--NVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKL 175
           +KP PP   ++ +T  G   ISW S    P        LQY+++Y +      +    K+
Sbjct: 235 VKPDPPLGLHMEITDDGNLKISWSSPPLVPF------PLQYQVKY-SENSTTVIREADKI 287

Query: 176 ISVDSRSV-SLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
           +S  S  V S+LP      SSYE+QVR   + G    G WS+WS P +F TQ
Sbjct: 288 VSATSLLVDSILP-----GSSYEVQVRGKRLDGP---GIWSDWSTPRVFTTQ 331



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 44/230 (19%)

Query: 79  YTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS---GQYN 135
           Y C       ++     + I    G+        L    +KP PP +V    +   G   
Sbjct: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555

Query: 136 ISWRSDYEDPAFYMLKGKLQYELQYRNRGDP--WAVSPRRKLISVDSRSVSLLPLEFRKD 193
           ISW    E P F   +  LQ++++Y   G    W +    ++    S+SVSL   +    
Sbjct: 556 ISW----EKPVFP--ENNLQFQIRYGLSGKEVQWKMY---EVYDAKSKSVSLPVPDLC-- 604

Query: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
           + Y +QVR   + G  Y   WS WS+P                + +++ + V +  P FW
Sbjct: 605 AVYAVQVRCKRLDGLGY---WSNWSNPA---------------YTVVMDIKVPMRGPEFW 646

Query: 254 SL-------KTHPLWRLWKKIW---AVPSPERFFMPLYKGCSGDFKKWVG 293
            +       K   +  LWK +    ++ S +R+ +  +  C+G + + VG
Sbjct: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVG 696


>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
          Length = 1165

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)

Query: 118 IKPAPPF--NVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKL 175
           +KP PP   ++ +T  G   ISW S    P        LQY+++Y +      +    K+
Sbjct: 235 VKPDPPLGLHMEITDDGNLKISWSSPPLVPF------PLQYQVKY-SENSTTVIREADKI 287

Query: 176 ISVDSRSV-SLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
           +S  S  V S+LP      SSYE+QVR   + G    G WS+WS P +F TQ
Sbjct: 288 VSATSLLVDSILP-----GSSYEVQVRGKRLDGP---GIWSDWSTPRVFTTQ 331



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 52/230 (22%), Positives = 91/230 (39%), Gaps = 44/230 (19%)

Query: 79  YTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS---GQYN 135
           Y C       ++     + I    G+        L    +KP PP +V    +   G   
Sbjct: 496 YECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK 555

Query: 136 ISWRSDYEDPAFYMLKGKLQYELQYRNRGDP--WAVSPRRKLISVDSRSVSLLPLEFRKD 193
           ISW    E P F   +  LQ++++Y   G    W +    ++    S+SVSL   +    
Sbjct: 556 ISW----EKPVFP--ENNLQFQIRYGLSGKEVQWKMY---EVYDAKSKSVSLPVPDLC-- 604

Query: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
           + Y +QVR   + G  Y   WS WS+P                + +++ + V +  P FW
Sbjct: 605 AVYAVQVRCKRLDGLGY---WSNWSNPA---------------YTVVMDIKVPMRGPEFW 646

Query: 254 SL-------KTHPLWRLWKKIW---AVPSPERFFMPLYKGCSGDFKKWVG 293
            +       K   +  LWK +    ++ S +R+ +  +  C+G + + VG
Sbjct: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVG 696


>gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo
           sapiens]
          Length = 371

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 91/377 (24%), Positives = 146/377 (38%), Gaps = 66/377 (17%)

Query: 5   WAAPLLLLLLQGGW----------GCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQ 54
           W A + LL   GGW          G    + Y + L+TV           + LT  ++  
Sbjct: 8   WGAAVFLL---GGWMALGQGGAAEGVQIQIIYFN-LETVQVTWNASKYSRTNLTFHYRFN 63

Query: 55  YEELKDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLL 114
            +E  D+ T+  L          T  C +D      DDI   +I  ++G +     S  +
Sbjct: 64  GDEAYDQCTNYLLQEGH------TSGCLLDAEQ--RDDILYFSI--RNGTHPVFTASRWM 113

Query: 115 AESIKPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLK-GKLQYELQYRNRGDPWAVSPRR 173
              +KP+ P +V          SW  D        L  G L YE+QYR+  D    S + 
Sbjct: 114 VYYLKPSSPKHV--------RFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQSKQE 165

Query: 174 KLISVDSRSVSLLPLEFRKDSSYELQVRA-----GPMPGSSYQGTWSE---WSDPVIFQT 225
                ++ +V++  L+  K  S+ ++V+A     GP    +Y   WSE   W    I + 
Sbjct: 166 -----NTCNVTIEGLDAEKCYSFWVRVKAMEDVYGP---DTYPSDWSEVTCWQRGEI-RD 216

Query: 226 QSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWRLWKK----IWAVPSPERFFMPLY 281
              E      P L   +L+  + I    SL    LW+LW+     I +VP P+  F  L+
Sbjct: 217 ACAETPTPPKPKLSKFILISSLAILLMVSLLLLSLWKLWRVKKFLIPSVPDPKSIFPGLF 276

Query: 282 KGCSGDFKKWVG--------APFTGSSLELGPWSPEVPSTLEVYSCHP----PRSPAKRL 329
           +   G+F++W+             G+  E GP  P V    +  +  P    P++  K  
Sbjct: 277 EIHQGNFQEWITDTQNVAHLHKMAGAEQESGPEEPLVVQLAKTEAESPRMLDPQTEEKEA 336

Query: 330 QLTELQEPAELVESDGV 346
               LQ P + ++   V
Sbjct: 337 SGGSLQLPHQPLQGGDV 353


>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 69/272 (25%), Positives = 105/272 (38%), Gaps = 53/272 (19%)

Query: 117 SIKPAPPFNVTVTFSGQ-YNISW-----RSDYEDPAFYMLKGKLQYELQYRNRGDPWAVS 170
           +I+ APP ++ VT  G  Y++ W     R ++ D  F         E+QYR     W  S
Sbjct: 337 NIQMAPP-SLNVTKDGDSYSLRWETMKMRYEHIDHTF---------EIQYRKDTATWKDS 386

Query: 171 PRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEEL 230
               L +  S ++  L    R    Y  +VR      + Y G WSEWS+   + T+S  +
Sbjct: 387 KTETLQNAHSMALPALEPSTR----YWARVRVRTSR-TGYNGIWSEWSEARSWDTES--V 439

Query: 231 KEGWNPHLLLLLLLVIVFIP-AFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFK 289
              W   L+++ L + V +   F  +  + L R W++    PS    F       +G  +
Sbjct: 440 LPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPNPSKSHLFQ------NGSAE 493

Query: 290 KW----VGAPFTGSSLELGPWS---PEV--------------PSTLE--VYSCHPPRSPA 326
            W    + A  +GS    GPW    PE+              P T+E   + C PP  P 
Sbjct: 494 LWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPD 553

Query: 327 KRLQLTELQEPAELVESDGVPKPSFWPTAQNS 358
                ++L          G P  S  P  Q S
Sbjct: 554 TTPAASDLPTEQPPSPQPGPPAASHTPEKQAS 585



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 114 LAESIKPAPPFNVTV-TFSGQYNISWRSDYEDPAFYMLK-GKLQYELQYRNRGDPWAVSP 171
           L + ++P  P ++ + T    + ++W      P  + L  G L++E+ Y+   D W  + 
Sbjct: 127 LTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQDSWEDAA 186

Query: 172 RRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQ 226
              ++  ++   +L P      S+Y  +VR    PGS   G  S+WS  V + +Q
Sbjct: 187 ---ILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQ 238


>gi|4885491 myeloproliferative leukemia virus oncogene precursor
           [Homo sapiens]
          Length = 635

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 71/282 (25%), Positives = 104/282 (36%), Gaps = 44/282 (15%)

Query: 14  LQGGWGCPDLVCYTDYLQTVICI-LEMWNLHPSTLTLTWQDQYEELKD------EATSCS 66
           L G WG   L    D     + + L+ + L    +T  WQ Q             A  C 
Sbjct: 265 LGGSWGSWSLPVTVDLPGDAVALGLQCFTLDLKNVTCQWQQQDHASSQGFFYHSRARCCP 324

Query: 67  LHR--------SAHNATHATYTCHMDVFHFMA--DDIFS--VNITDQSGNYSQECGS-FL 113
             R                  T      HF +  D I    V +T   G      GS F 
Sbjct: 325 RDRYPIWENCEEEEKTNPGLQTPQFSRCHFKSRNDSIIHILVEVTTAPGTVHSYLGSPFW 384

Query: 114 LAESIK-PAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRG-DPWAVSP 171
           + ++++ P P  +     SG   + W    + P+ +  + +  Y+L+Y   G   W V  
Sbjct: 385 IHQAVRLPTPNLHWREISSGHLELEW----QHPSSWAAQ-ETCYQLRYTGEGHQDWKVLE 439

Query: 172 RRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELK 231
                 + +R  +L   E R  S Y LQ+RA  + G +YQG WS WSDP   +T +E   
Sbjct: 440 P----PLGARGGTL---ELRPRSRYRLQLRAR-LNGPTYQGPWSSWSDPTRVETATE--- 488

Query: 232 EGWNP-----HLLLLLLLVIVFIPAFWSLKTHPLWRLWKKIW 268
             W       HL+L L  V+  +   W    H   RL   +W
Sbjct: 489 TAWISLVTALHLVLGLSAVLGLLLLRWQFPAH-YRRLRHALW 529



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 1/56 (1%)

Query: 166 PWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPV 221
           P   SP R+  ++ +   S L    +  +SY LQ+R+ P  G S  G+W  WS PV
Sbjct: 222 PKQTSPSREASALTAEGGSCLISGLQPGNSYWLQLRSEP-DGISLGGSWGSWSLPV 276


>gi|56788411 interleukin 4 receptor alpha chain isoform b precursor
           [Homo sapiens]
          Length = 227

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 50/196 (25%), Positives = 79/196 (40%), Gaps = 15/196 (7%)

Query: 25  CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84
           C +DY+    C  +M      +  L    Q   L  EA +C       N   A   CH+ 
Sbjct: 34  CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89

Query: 85  VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142
           +   ++ D +++++   +G      GSF  +E +KP  P N+TV    S    ++W + Y
Sbjct: 90  MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147

Query: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202
             P    L   L Y +   +  DP     R   ++    S+ +     +   SY  +VRA
Sbjct: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203

Query: 203 GPMPGSSYQGTWSEWS 218
                  Y  TWSEWS
Sbjct: 204 W---AQCYNTTWSEWS 216


>gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo
           sapiens]
          Length = 259

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 51/188 (27%), Positives = 82/188 (43%), Gaps = 30/188 (15%)

Query: 118 IKPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLK-GKLQYELQYRNRGDPWAVSPRRKLI 176
           +KP+ P +V          SW  D        L  G L YE+QYR+  D    S +    
Sbjct: 5   LKPSSPKHV--------RFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQSKQE--- 53

Query: 177 SVDSRSVSLLPLEFRKDSSYELQVRA-----GPMPGSSYQGTWSE---WSDPVIFQTQSE 228
             ++ +V++  L+  K  S+ ++V+A     GP    +Y   WSE   W    I +    
Sbjct: 54  --NTCNVTIEGLDAEKCYSFWVRVKAMEDVYGP---DTYPSDWSEVTCWQRGEI-RDACA 107

Query: 229 ELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWRLWKK----IWAVPSPERFFMPLYKGC 284
           E      P L   +L+  + I    SL    LW+LW+     I +VP P+  F  L++  
Sbjct: 108 ETPTPPKPKLSKFILISSLAILLMVSLLLLSLWKLWRVRKFLIPSVPDPKSIFPGLFEIH 167

Query: 285 SGDFKKWV 292
            G+F++W+
Sbjct: 168 QGNFQEWI 175


>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
          Length = 369

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 96/234 (41%), Gaps = 34/234 (14%)

Query: 21  PDLVCYTDYLQTVICILEMWNL----HPSTLTLTWQDQYEELKDEATSCSLHRSAHNATH 76
           P++ C+   ++ + C    WN      P+ LTL +  +  +  D+   CS +  +   T 
Sbjct: 58  PEVQCFVFNVEYMNCT---WNSSSEPQPTNLTLHYWYKNSD-NDKVQKCSHYLFSEEITS 113

Query: 77  ATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQY 134
               C +          F V + D      Q      L   + P  P N+T+      Q 
Sbjct: 114 G---CQLQKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQL 170

Query: 135 NISWRSDYEDPAFYMLKGKLQYELQYRNRGD-PWAVSPRRKLISVDSRSVSLLP-LEFRK 192
            ++W + +       L   L++ +QYR   D  W         SVD R    LP ++ +K
Sbjct: 171 ELNWNNRF-------LNHCLEHLVQYRTDWDHSWTEQ------SVDYRHKFSLPSVDGQK 217

Query: 193 DSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVI 246
             ++ ++ R  P+ GS+    WSEWS P+ + + +   KE  NP L  L  +VI
Sbjct: 218 RYTFRVRSRFNPLCGSAQH--WSEWSHPIHWGSNTS--KE--NPFLFALEAVVI 265


>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
           sapiens]
          Length = 420

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 18/162 (11%)

Query: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
           PP NVT    G + +I W    E P          YE++  N         R   + ++ 
Sbjct: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288

Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
              +         S Y++QVRA         G WSEWS P+       +    W    ++
Sbjct: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREW---FVI 345

Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIW-AVPSPERFFMPLY 281
           +++  I FI    SL    +  LW K++  +P+P+     L+
Sbjct: 346 VIMATICFILLILSL-ICKICHLWIKLFPPIPAPKSNIKDLF 386


>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
           sapiens]
          Length = 420

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 39/162 (24%), Positives = 63/162 (38%), Gaps = 18/162 (11%)

Query: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
           PP NVT    G + +I W    E P          YE++  N         R   + ++ 
Sbjct: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288

Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL 240
              +         S Y++QVRA         G WSEWS P+       +    W    ++
Sbjct: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREW---FVI 345

Query: 241 LLLLVIVFIPAFWSLKTHPLWRLWKKIW-AVPSPERFFMPLY 281
           +++  I FI    SL    +  LW K++  +P+P+     L+
Sbjct: 346 VIMATICFILLILSL-ICKICHLWIKLFPPIPAPKSNIKDLF 386


>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
          Length = 422

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 42/164 (25%), Positives = 70/164 (42%), Gaps = 19/164 (11%)

Query: 75  THATYTCHM--DVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSG 132
           T   ++CH+  D+  F   +I+ V  T++ G+   +  +  + + +   PP +V V+  G
Sbjct: 189 TVGPHSCHIPKDLALFTPYEIW-VEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVG 247

Query: 133 ----QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGD-PWAVSPRRKLISVDSRSVSLLP 187
               Q ++ W S    PA      + +Y+++YR      W      K++   S   S   
Sbjct: 248 GLEDQLSVRWVSP---PALKDFLFQAKYQIRYRVEDSVDW------KVVDDVSNQTSCRL 298

Query: 188 LEFRKDSSYELQVRAGPMP--GSSYQGTWSEWSDPVIFQTQSEE 229
              +  + Y +QVR  P    GS   G WSEWS P    T   E
Sbjct: 299 AGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSE 342


>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
           [Homo sapiens]
          Length = 918

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 36/177 (20%), Positives = 72/177 (40%), Gaps = 20/177 (11%)

Query: 59  KDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESI 118
           +D  TSC++  S        Y  +++V+         V   +  G  + +  +F     +
Sbjct: 176 RDTPTSCTVDYST------VYFVNIEVW---------VEAENALGKVTSDHINFDPVYKV 220

Query: 119 KPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNR-GDPWAVSPRRKLIS 177
           KP PP N++V  S + +   +  + +P+   +   L+Y +QYR +    W+  P     S
Sbjct: 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTAS 279

Query: 178 VDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGW 234
             S   S    + +  + Y  ++R     G  Y   WSE +  + ++ +  +    W
Sbjct: 280 TRS---SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333


>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
           [Homo sapiens]
          Length = 329

 Score = 37.4 bits (85), Expect = 0.035
 Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 23/162 (14%)

Query: 59  KDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESI 118
           +D  TSC++  S        Y  +++V+         V   +  G  + +  +F     +
Sbjct: 176 RDTPTSCTVDYST------VYFVNIEVW---------VEAENALGKVTSDHINFDPVYKV 220

Query: 119 KPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNR-GDPWAVSPRRKLIS 177
           KP PP N++V  S + +   +  + +P+   +   L+Y +QYR +    W+  P     S
Sbjct: 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTAS 279

Query: 178 VDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSD 219
             S   S    + +  + Y  ++R     G  Y   WS+WS+
Sbjct: 280 TRS---SFTVQDLKPFTEYVFRIRCMKEDGKGY---WSDWSE 315


>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
           sapiens]
          Length = 468

 Score = 37.0 bits (84), Expect = 0.046
 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 19/132 (14%)

Query: 93  IFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRS-DYEDP-----A 146
           I S+ +    G+   +  +F     ++P PP N+TVT   + N  W S  ++DP     +
Sbjct: 189 IVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVAR-NPRWLSVTWQDPHSWNSS 247

Query: 147 FYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMP 206
           FY L+ +L+Y  +       W V   +    +      L          + +Q+RA    
Sbjct: 248 FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL---------RHVVQLRAQEEF 298

Query: 207 GSSYQGTWSEWS 218
           G   QG WSEWS
Sbjct: 299 G---QGEWSEWS 307


>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
           sapiens]
          Length = 365

 Score = 37.0 bits (84), Expect = 0.046
 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 19/132 (14%)

Query: 93  IFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRS-DYEDP-----A 146
           I S+ +    G+   +  +F     ++P PP N+TVT   + N  W S  ++DP     +
Sbjct: 189 IVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVAR-NPRWLSVTWQDPHSWNSS 247

Query: 147 FYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMP 206
           FY L+ +L+Y  +       W V   +    +      L          + +Q+RA    
Sbjct: 248 FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL---------RHVVQLRAQEEF 298

Query: 207 GSSYQGTWSEWS 218
           G   QG WSEWS
Sbjct: 299 G---QGEWSEWS 307


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 36.6 bits (83), Expect = 0.060
 Identities = 47/163 (28%), Positives = 62/163 (38%), Gaps = 31/163 (19%)

Query: 386  GPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSL 445
            GP     S  D G P +    G    PG   P  D G +       + G+PGL GP GS 
Sbjct: 960  GPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISG------TPGAPGLPGPKGS- 1012

Query: 446  LDRLKPPLADGEDWAGGLPWGGRSPG-------GVSESEAGSP---LAGLDMDTFDSGFV 495
            +  +  P   GE    G+P    SPG          + +AG P   + GL  +  D G  
Sbjct: 1013 VGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIA 1072

Query: 496  GSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS 538
            G            SPG++G   S     + IP    SPG + S
Sbjct: 1073 GFP---------GSPGEKGEKGS-----IGIPGMPGSPGLKGS 1101



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 35/121 (28%), Positives = 43/121 (35%), Gaps = 4/121 (3%)

Query: 398 GYPALDLDAGLEPSPGL--EDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLAD 455
           G+P    D G    PG     P+ D G      G  S G PG  G  G ++    PP A+
Sbjct: 592 GFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAE 651

Query: 456 GEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGP 515
           G   + G P G +   G   +     L G        G        P   D   PGD GP
Sbjct: 652 GLPGSPGFP-GPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVD-GLPGDMGP 709

Query: 516 P 516
           P
Sbjct: 710 P 710



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 40/151 (26%), Positives = 49/151 (32%), Gaps = 41/151 (27%)

Query: 396 DDGYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSA----GSPGLGGPLGSLLDRLKP 451
           + GYP L    G +   G   P    G  V+  G +      G PG  GP G        
Sbjct: 306 EPGYPGLIGRQGPQGEKGEAGPPGPPGI-VIGTGPLGEKGERGYPGTPGPRGE------- 357

Query: 452 PLADGEDWAGGLPWGGRSPGGVSESEAGSP-LAGLDMDTFDSGFVGSDCSSP-------- 502
               G     GLP     PG     +AG+P   G   +  D GF G+    P        
Sbjct: 358 ---PGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPG 414

Query: 503 -----------------VECDFTSPGDEGPP 516
                            VEC    PGD+GPP
Sbjct: 415 PPGSPGPPGQPGYTNGIVECQPGPPGDQGPP 445


>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
          Length = 862

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 21/138 (15%)

Query: 96  VNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS----GQYNISWRSDYEDPAFYMLK 151
           V   +  G+ S    +F   + ++P PP+++ + F      +  + WR    D    +L 
Sbjct: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLN 255

Query: 152 GKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQ 211
                 L+YR        S    +++V         L+ +  + YE Q+ +       Y+
Sbjct: 256 -----RLRYRPSN-----SRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKL---HLYK 302

Query: 212 GTWSEWSDPVIFQTQSEE 229
           G+WS+WS+ +  QT  EE
Sbjct: 303 GSWSDWSESLRAQTPEEE 320


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 14/133 (10%)

Query: 397  DGYPALDLDAGL---EPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSL-------- 445
            DG P L  + G+   E  PGL+ P    G           G+PGL GP G          
Sbjct: 2149 DGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGE 2208

Query: 446  LDRLKPPLAD--GEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPV 503
                 PP     G   A GLP G   P G+   +    L G   +T   G  G D +S  
Sbjct: 2209 PGETGPPGRGLTGPTGAVGLP-GPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGK 2267

Query: 504  ECDFTSPGDEGPP 516
            + D  SPG  G P
Sbjct: 2268 DGDRGSPGVPGSP 2280



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 41/144 (28%), Positives = 52/144 (36%), Gaps = 20/144 (13%)

Query: 396  DDGYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKP--PL 453
            D G P LD  +GL+  PG   P    G    +      G PGL G  G       P  P 
Sbjct: 1771 DRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPG 1830

Query: 454  ADGEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECDFTSP--- 510
              GED   GL      PG   E        G   +  DSG  G +     + +  +P   
Sbjct: 1831 KPGEDGKPGLNGKNGEPGDPGED-------GRKGEKGDSGASGREGRDGPKGERGAPGIL 1883

Query: 511  GDEGPPRSYLRQWVVIPPPLSSPG 534
            G +GPP         +P P+  PG
Sbjct: 1884 GPQGPPG--------LPGPVGPPG 1899



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 27/85 (31%), Positives = 32/85 (37%), Gaps = 18/85 (21%)

Query: 434  GSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGV--SESEAGSPLAGLDMDTFD 491
            G PG+ GP G   DR  PP  DG     G P G   P G   +  +AG P          
Sbjct: 1758 GDPGVRGPAGEKGDR-GPPGLDGRSGLDGKP-GAAGPSGPNGAAGKAGDP---------- 1805

Query: 492  SGFVGSDCSSPVECDFTSPGDEGPP 516
                G D    +  +   PG  GPP
Sbjct: 1806 ----GRDGLPGLRGEQGLPGPSGPP 1826



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 14/117 (11%)

Query: 405  DAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPP----LADGEDWA 460
            D+G +  PG E P+   G   L       G PG  GP G  L    PP    LA GE   
Sbjct: 1983 DSGEQGPPGKEGPIGFPGERGLKG---DRGDPGPQGPPGLALGERGPPGPSGLA-GEPGK 2038

Query: 461  GGLPWGGRSPGGVSESEAGSP-LAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPP 516
             G+P      GGV   EAG P   G   +  + G  G D    +     +PG  GPP
Sbjct: 2039 PGIPGLPGRAGGV--GEAGRPGERGERGEKGERGEQGRDGPPGLP---GTPGPPGPP 2090



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 30/83 (36%), Positives = 35/83 (42%), Gaps = 12/83 (14%)

Query: 434  GSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSG 493
            GSPG  GP+G      K    D ED A GLP    SPG   +   G P  G      D G
Sbjct: 1430 GSPGPQGPVGP--PGKKGEKGDSEDGAPGLPGQPGSPG--EQGPRGPP--GAIGPKGDRG 1483

Query: 494  FVGSDCSSPVECDFTSPGDEGPP 516
            F G     P+  +    G+ GPP
Sbjct: 1484 FPG-----PLG-EAGEKGERGPP 1500


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 47/144 (32%), Positives = 52/144 (36%), Gaps = 28/144 (19%)

Query: 398  GYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSA-GSPGLGGPLGSLLDRLKPPLADG 456
            G+P      GL+  PG   P  + G T    G V   G PG  GP G       P  A G
Sbjct: 1219 GFPGPPGPVGLQGLPG---PPGEKGET----GDVGQMGPPGPPGPRG-------PSGAPG 1264

Query: 457  EDWAGGLPWGGRSPGGVSE----SEAGSP-LAGLDMDTFDSGFVGSDCSSPVECDFTSPG 511
             D   G P G  +PG V E     EAG P L G        G  G    S        PG
Sbjct: 1265 ADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPG 1324

Query: 512  DEGPPRSYLRQWVVIPPPLSSPGP 535
             +GPP            P  SPGP
Sbjct: 1325 PKGPPGD--------DGPKGSPGP 1340


>gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [Homo
           sapiens]
          Length = 333

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 13/101 (12%)

Query: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
           PP NVT    G + +I W    E P          YE++  N         R   + ++ 
Sbjct: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288

Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPV 221
              +         S Y++QVRA         G WSEWS P+
Sbjct: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPI 329


>gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [Homo
           sapiens]
          Length = 335

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 13/101 (12%)

Query: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180
           PP NVT    G + +I W    E P          YE++  N         R   + ++ 
Sbjct: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288

Query: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPV 221
              +         S Y++QVRA         G WSEWS P+
Sbjct: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPI 329


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.137    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,252,803
Number of Sequences: 37866
Number of extensions: 1537894
Number of successful extensions: 4439
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 4246
Number of HSP's gapped (non-prelim): 271
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press