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Search of human proteins with 30840978
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30840978 neuroligin 2 [Homo sapiens]
(835 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30840978 neuroligin 2 [Homo sapiens] 1741 0.0
gi|51593088 neuroligin 3 [Homo sapiens] 1056 0.0
gi|7662470 neuroligin 1 [Homo sapiens] 1049 0.0
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 1033 0.0
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 1033 0.0
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 1016 0.0
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 312 7e-85
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 303 6e-82
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 301 2e-81
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 291 1e-78
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 291 2e-78
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 290 5e-78
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 286 5e-77
gi|33563374 carboxylesterase 3 [Homo sapiens] 282 8e-76
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 280 4e-75
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 276 6e-74
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 269 7e-72
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 254 3e-67
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 230 4e-60
gi|55770862 thyroglobulin [Homo sapiens] 189 7e-48
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 153 7e-37
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 152 1e-36
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 93 9e-19
gi|33356148 formin-like 1 [Homo sapiens] 58 4e-08
gi|153792074 proline rich 12 [Homo sapiens] 53 1e-06
gi|11386183 WAS protein family, member 2 [Homo sapiens] 53 1e-06
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 52 2e-06
gi|160707881 formin 2 [Homo sapiens] 52 2e-06
gi|28872794 CCAAT/enhancer binding protein alpha [Homo sapiens] 51 5e-06
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 50 1e-05
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 1741 bits (4508), Expect = 0.0
Identities = 835/835 (100%), Positives = 835/835 (100%)
Query: 1 MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNN 60
MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNN
Sbjct: 1 MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNN 60
Query: 61 EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLP 120
EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLP
Sbjct: 61 EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLP 120
Query: 121 VWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVM 180
VWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVM
Sbjct: 121 VWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVM 180
Query: 181 LFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQ 240
LFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQ
Sbjct: 181 LFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQ 240
Query: 241 ALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV 300
ALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV
Sbjct: 241 ALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV 300
Query: 301 NYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVV 360
NYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVV
Sbjct: 301 NYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVV 360
Query: 361 PDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGY 420
PDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGY
Sbjct: 361 PDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGY 420
Query: 421 PEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYF 480
PEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYF
Sbjct: 421 PEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYF 480
Query: 481 YTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTN 540
YTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTN
Sbjct: 481 YTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTN 540
Query: 541 FAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAF 600
FAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAF
Sbjct: 541 FAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAF 600
Query: 601 WLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPR 660
WLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPR
Sbjct: 601 WLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPR 660
Query: 661 AYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGS 720
AYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGS
Sbjct: 661 AYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGS 720
Query: 721 GVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDV 780
GVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDV
Sbjct: 721 GVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDV 780
Query: 781 PLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV 835
PLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV
Sbjct: 781 PLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV 835
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 1056 bits (2732), Expect = 0.0
Identities = 528/814 (64%), Positives = 627/814 (77%), Gaps = 47/814 (5%)
Query: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
P VNT +G++RG R L +EILGPV Q+LGVPYA PP+G +RF PPE P SW G+RNAT
Sbjct: 42 PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
Query: 102 LPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDE 161
PP CPQN+H A+P +MLPVWFT NL+ ATY+Q +EDCLYLN+YVPTEDG KK+ E
Sbjct: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGE 161
Query: 162 ATLN---PPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGV 218
+ D DIRD G KPVM+++HGGSYMEGTGNM DGS+LA+YGNVIV TLNYR+GV
Sbjct: 162 DLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGV 221
Query: 219 LGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSH 278
LGFLSTGDQAAKGNYGLLDQIQALRW+SENIA FGGDP RIT+FGSG GASCV+LL LSH
Sbjct: 222 LGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSH 281
Query: 279 HSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELV 338
HSEGLFQ+AI QSG+A+SSW+VNYQP+KYT LLA KVGC+ D+ + V+CLR+K ++ELV
Sbjct: 282 HSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELV 341
Query: 339 DQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESE 398
+QD+QPARYH+AFGPV+DGDV+PDDPEILM+QGEFLNYD+++GVNQGEGLKFVE + E
Sbjct: 342 EQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPE 401
Query: 399 DGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDH 458
DGVS + FD++VSNFVDNLYGYPEGKD LRETIKFMYTDWADRDN E RRKTL+ALFTDH
Sbjct: 402 DGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDH 461
Query: 459 QWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDL 518
QWV P+V TA LHA Y SP YFY FYHHCQ+ +P W+DAAHGDE+PYVFGVPMVG TDL
Sbjct: 462 QWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDL 521
Query: 519 FPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEK 578
FPCNFSKNDVMLSAVVMTYWTNFAKTGDPN+PVPQDTKFIHTK NRFEEV WSK+N +++
Sbjct: 522 FPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQ 581
Query: 579 QYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELF---TTTTRLPP----YATRWPP 631
YLHIGLKPRVRD+YRA KVAFW LVPHL+NLH ++F +TTT++PP +++
Sbjct: 582 LYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLH-DMFHYTSTTTKVPPPDTTHSSHITR 640
Query: 632 RPPAGAPGTRRPPPPATLPPE-------PEPEPGPRAYDRFPGDSRDYSTELSVTVAVGA 684
RP T+RP E + + GP + + RDYSTELSVT+AVGA
Sbjct: 641 RPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVE----NPRDYSTELSVTIAVGA 696
Query: 685 SLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVS 744
SLLFLN+LAFAALYY++D+R++ R+ SP G+G+ P L AA PEEEL +
Sbjct: 697 SLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGA------PELGAA-----PEEELAA 745
Query: 745 LQL--KRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPP 802
LQL P + LR PDYTL LRR+PDD+PL+ P +T++P+ L
Sbjct: 746 LQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSL-----VG 800
Query: 803 PPSLHPFGPFPPPPPTATSHNNT-LPHPHSTTRV 835
+LHP+ F A N+T LPH HSTTRV
Sbjct: 801 LQTLHPYNTF------AAGFNSTGLPHSHSTTRV 828
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 1049 bits (2713), Expect = 0.0
Identities = 522/812 (64%), Positives = 617/812 (75%), Gaps = 59/812 (7%)
Query: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
P+V T +G++RG+++ELNNEILGPV+QFLGVPYA PP G RRFQPPE P+ W +RNAT
Sbjct: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
Query: 102 LPPACPQNL-HGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRD 160
P CPQN+ G LP +MLPVWFT+NL+ ++YVQ+QSEDCLYLN+YVPTED
Sbjct: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTED-------- 164
Query: 161 EATLNPPDTDIRDPG-KKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVL 219
DIRD G KPVM+++HGGSYMEGTGN++DGSVLA+YGNVIV T+NYRLGVL
Sbjct: 165 ---------DIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVL 215
Query: 220 GFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHH 279
GFLSTGDQAAKGNYGLLD IQALRW SENI FGGDP RIT+FGSGAG SCVNLL LSH+
Sbjct: 216 GFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHY 275
Query: 280 SEG---------LFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLR 330
SEG LFQ+AIAQSGTA+SSW+V++QP KY R+LA KVGC+ D+ E VECL+
Sbjct: 276 SEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQ 335
Query: 331 RKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKF 390
+KP +ELVDQD+QPARYHIAFGPV+DGDV+PDDP+ILM+QGEFLNYD+++GVNQGEGLKF
Sbjct: 336 KKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKF 395
Query: 391 VEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKT 450
VE+ +S+DG+SAS FDF VSNFVDNLYGYPEGKDVLRETIKFMYTDWADR N E RRKT
Sbjct: 396 VENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKT 455
Query: 451 LLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGV 510
LLALFTDHQWVAPAVATA LH+++ SP YFY FYHHCQ + P WADAAHGDE+PYV G+
Sbjct: 456 LLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGI 515
Query: 511 PMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVW 570
PM+G T+LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEV W
Sbjct: 516 PMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAW 575
Query: 571 SKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLH--TELFTTTTRLPPYATR 628
++++ K++ YLHIGLKPRV+++YRANKV WLELVPHLHNL+ ++ +TTT++P
Sbjct: 576 TRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDIT 635
Query: 629 WPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLF 688
+ P P T P P+ +P P F D RDYSTELSVT+AVGASLLF
Sbjct: 636 FRPTRKNSVPVTSAFPTAKQDDPKQQPSP-------FSVDQRDYSTELSVTIAVGASLLF 688
Query: 689 LNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLK 748
LNILAFAALYYK+D+R+ RR SP + + + EEE++SLQ+K
Sbjct: 689 LNILAFAALYYKKDKRRHDVHRRCSPQRTTTNDLTHA------------QEEEIMSLQMK 736
Query: 749 RGG----GVGADPAE-ALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPP 803
P E LR ACPPDYTLA+RR+PDDVPL+ P +T++P+ + P
Sbjct: 737 HTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTI-----PGI 791
Query: 804 PSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV 835
LH F F H + PH HSTTRV
Sbjct: 792 QPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 823
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1033 bits (2671), Expect = 0.0
Identities = 519/816 (63%), Positives = 616/816 (75%), Gaps = 59/816 (7%)
Query: 38 EERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVR 97
+ ++PVVNT YG++RG+R L NEILGPV Q+LGVPYA+PP G RRFQPPE P+SW G+R
Sbjct: 42 QAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIR 101
Query: 98 NATTLPPACPQNL-HGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLT 156
N T CPQ+L +L MLP+WFT NL+ TYVQ+Q+EDCLYLN+YVPTED
Sbjct: 102 NTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTED---- 157
Query: 157 KKRDEATLNPPDTDIRDPG-KKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYR 215
DI D KKPVM+++HGGSYMEGTGNM DGS+LA+YGNVIV T+NYR
Sbjct: 158 -------------DIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYR 204
Query: 216 LGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLI 275
LG+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+R+TIFGSGAGASCV+LL
Sbjct: 205 LGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLT 264
Query: 276 LSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSR 335
LSH+SEGLFQKAI QSGTA+SSW+VNYQP KYTR+LA KVGC+ D+ + VECLR K +
Sbjct: 265 LSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYK 324
Query: 336 ELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSA 395
EL+ Q + PA YHIAFGPV+DGDV+PDDP+ILM+QGEFLNYD+++GVNQGEGLKFV+
Sbjct: 325 ELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIV 384
Query: 396 ESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALF 455
++EDGV+ + FDF+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD++N E RRKTL+ALF
Sbjct: 385 DNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALF 444
Query: 456 TDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGA 515
TDHQWVAPAVATA LHA Y SP YFY FYHHCQ+E +P WAD+AHGDE+PYVFG+PM+G
Sbjct: 445 TDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGP 504
Query: 516 TDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNS 575
T+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEV WSK+N
Sbjct: 505 TELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNP 564
Query: 576 KEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELF---TTTTRLP-------PY 625
K++ YLHIGLKPRVRD+YRA KVAFWLELVPHLHNL+ E+F +TTT++P PY
Sbjct: 565 KDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLN-EIFQYVSTTTKVPPPDMTSFPY 623
Query: 626 ATRWPPRPPAGA-PGTRRPPPPATLPPEPEPEP---GPRAYDRFPGDSRDYSTELSVTVA 681
TR R PA P T+RP P+ +P GP RDYSTELSVT+A
Sbjct: 624 GTR---RSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIA 680
Query: 682 VGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVP--GGGPLLPAAGRELPPE 739
VGASLLFLNILAFAALYYK+D+R+ RR SP + + + ++ ++L +
Sbjct: 681 VGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHD 740
Query: 740 EELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPP 799
E SLQ + LR CPPDYTL LRR+PDD+PL+ P +T++P+ L
Sbjct: 741 HECESLQAH----------DTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQ 790
Query: 800 PPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV 835
P LH F F + ++ LPH HSTTRV
Sbjct: 791 P-----LHTFNTF-----SGGQNSTNLPHGHSTTRV 816
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1033 bits (2671), Expect = 0.0
Identities = 519/816 (63%), Positives = 616/816 (75%), Gaps = 59/816 (7%)
Query: 38 EERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVR 97
+ ++PVVNT YG++RG+R L NEILGPV Q+LGVPYA+PP G RRFQPPE P+SW G+R
Sbjct: 42 QAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIR 101
Query: 98 NATTLPPACPQNL-HGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLT 156
N T CPQ+L +L MLP+WFT NL+ TYVQ+Q+EDCLYLN+YVPTED
Sbjct: 102 NTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTED---- 157
Query: 157 KKRDEATLNPPDTDIRDPG-KKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYR 215
DI D KKPVM+++HGGSYMEGTGNM DGS+LA+YGNVIV T+NYR
Sbjct: 158 -------------DIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYR 204
Query: 216 LGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLI 275
LG+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+R+TIFGSGAGASCV+LL
Sbjct: 205 LGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLT 264
Query: 276 LSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSR 335
LSH+SEGLFQKAI QSGTA+SSW+VNYQP KYTR+LA KVGC+ D+ + VECLR K +
Sbjct: 265 LSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYK 324
Query: 336 ELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSA 395
EL+ Q + PA YHIAFGPV+DGDV+PDDP+ILM+QGEFLNYD+++GVNQGEGLKFV+
Sbjct: 325 ELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIV 384
Query: 396 ESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALF 455
++EDGV+ + FDF+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD++N E RRKTL+ALF
Sbjct: 385 DNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALF 444
Query: 456 TDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGA 515
TDHQWVAPAVATA LHA Y SP YFY FYHHCQ+E +P WAD+AHGDE+PYVFG+PM+G
Sbjct: 445 TDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGP 504
Query: 516 TDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNS 575
T+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEV WSK+N
Sbjct: 505 TELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNP 564
Query: 576 KEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELF---TTTTRLP-------PY 625
K++ YLHIGLKPRVRD+YRA KVAFWLELVPHLHNL+ E+F +TTT++P PY
Sbjct: 565 KDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLN-EIFQYVSTTTKVPPPDMTSFPY 623
Query: 626 ATRWPPRPPAGA-PGTRRPPPPATLPPEPEPEP---GPRAYDRFPGDSRDYSTELSVTVA 681
TR R PA P T+RP P+ +P GP RDYSTELSVT+A
Sbjct: 624 GTR---RSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIA 680
Query: 682 VGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVP--GGGPLLPAAGRELPPE 739
VGASLLFLNILAFAALYYK+D+R+ RR SP + + + ++ ++L +
Sbjct: 681 VGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHD 740
Query: 740 EELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPP 799
E SLQ + LR CPPDYTL LRR+PDD+PL+ P +T++P+ L
Sbjct: 741 HECESLQAH----------DTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQ 790
Query: 800 PPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV 835
P LH F F + ++ LPH HSTTRV
Sbjct: 791 P-----LHTFNTF-----SGGQNSTNLPHGHSTTRV 816
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 1016 bits (2627), Expect = 0.0
Identities = 511/816 (62%), Positives = 613/816 (75%), Gaps = 59/816 (7%)
Query: 38 EERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVR 97
+ ++PVVNT YG+++G+R L +EILGPV Q+LGVPYA+PP G RRFQPPE+P+SW G+R
Sbjct: 42 QAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIR 101
Query: 98 NATTLPPACPQNLHGA-LPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLT 156
NAT CPQ+L L MLP+WFT +L+ TYVQ+Q+EDCLYLN+YVP ED
Sbjct: 102 NATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMED---- 157
Query: 157 KKRDEATLNPPDTDIRDPG-KKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYR 215
DI + KKPVM+++HGGSYMEGTGNM DGS+LA+YGNVIV T+N R
Sbjct: 158 -------------DIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCR 204
Query: 216 LGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLI 275
LG+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+R+TIFGSGAGASCV+LL
Sbjct: 205 LGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLT 264
Query: 276 LSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSR 335
LSH+SEGLFQKAI QSGTA+SSW+VNYQP KYTR+LA KVGC+ D+ + VECL+ K +
Sbjct: 265 LSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYK 324
Query: 336 ELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSA 395
EL+ Q + PA YHIAFGPV+DGDV+PDDP+ILM+QGEFLNYD+++GVNQGEGLKFV+
Sbjct: 325 ELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIV 384
Query: 396 ESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALF 455
++EDGV+ + FDF+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD++N E RRKTL+ALF
Sbjct: 385 DNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALF 444
Query: 456 TDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGA 515
TDHQWVAPAVATA LHA Y SP YFY FYHHCQ+E +P WAD+AHGDE+PYVFG+PM+G
Sbjct: 445 TDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGP 504
Query: 516 TDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNS 575
T+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEV WSK+N
Sbjct: 505 TELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNP 564
Query: 576 KEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELF---TTTTRLP-------PY 625
K++ YLHIGLKPRVRD+YRA KVAFWLELVPHLHNL+ E+F +TTT++P PY
Sbjct: 565 KDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLN-EIFQYVSTTTKVPPPDMTSFPY 623
Query: 626 ATRWPPRPPAGA-PGTRRPPPPATLPPEPEPEP---GPRAYDRFPGDSRDYSTELSVTVA 681
TR R PA P T+RP P+ +P GP RDYSTELSVT+A
Sbjct: 624 GTR---RSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIA 680
Query: 682 VGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVP--GGGPLLPAAGRELPPE 739
VGASLLFLNILAFAALYYK+D+R+ R SP + + + ++ ++L +
Sbjct: 681 VGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTNDITHIQNEEIMSLQMKQLEHD 740
Query: 740 EELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPP 799
E SLQ + LR CPPDYTL LRR+PDD+P + P +T++P+ L
Sbjct: 741 HECESLQAH----------DTLRLTCPPDYTLTLRRSPDDIPFMTPNTITMIPNTLMGMQ 790
Query: 800 PPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV 835
P LH F F + ++ LPH HSTTRV
Sbjct: 791 P-----LHTFKTF-----SGGQNSTNLPHGHSTTRV 816
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 312 bits (800), Expect = 7e-85
Identities = 194/577 (33%), Positives = 293/577 (50%), Gaps = 67/577 (11%)
Query: 43 VVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTL 102
++ T G+VRG+ + G V FLG+PYA PPLG RF+ P++ W + NAT
Sbjct: 33 IIATKNGKVRGMNLTVFG---GTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKY 89
Query: 103 PPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEA 162
+C QN+ + P + N + SEDCLYLN+++P
Sbjct: 90 ANSCCQNIDQSFPGFHGSEMWNPNTDL--------SEDCLYLNVWIPAPK---------- 131
Query: 163 TLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNM--FDGSVLAAYGNVIVATLNYRLGVLG 220
P V+++++GG + GT ++ +DG LA VIV ++NYR+G LG
Sbjct: 132 -----------PKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALG 180
Query: 221 FLST-GDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHH 279
FL+ G+ A GN GL DQ AL+W+ +NIA FGG+P+ +T+FG AGA+ V+L +LS
Sbjct: 181 FLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPG 240
Query: 280 SEGLFQKAIAQSGTAISSWSVN--YQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSREL 337
S LF +AI QSG+ + W+V Y+ T LA GC RE+ E ++CLR K +E+
Sbjct: 241 SHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEI 300
Query: 338 VDQDVQPARY----HIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVED 393
+ + Y + FGP VDGD + D P+IL++ G+F +L+GVN+ EG F+
Sbjct: 301 LLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVY 360
Query: 394 SAE--SEDGVSASAFDFTVSNFVDNL-YGYPEGKDVLRETIKFMYTDWADRDNGEMRRKT 450
A S+D S T F + L +P + +E+I F YTDW D E R+
Sbjct: 361 GAPGFSKDNNSI----ITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREA 416
Query: 451 LLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGV 510
L + D+ ++ PA+ K +++ + +FY F H PEW HG E+ +VFG+
Sbjct: 417 LGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGL 476
Query: 511 PMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVW 570
P+ N++K + +LS ++ W NFAK G+PN+ T W
Sbjct: 477 PLERRD-----NYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTS-------------W 518
Query: 571 SKFNSKEKQYLHIGLK-PRVRDNYRANKVAFWLELVP 606
F S E++YL + + R+ RA + FW P
Sbjct: 519 PVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFP 555
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 303 bits (775), Expect = 6e-82
Identities = 207/641 (32%), Positives = 302/641 (47%), Gaps = 87/641 (13%)
Query: 30 GLGLGSLGEERFPVVNTAYG-RVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPE 88
G G+G+ G E ++ T G R+RG+R + GPV FLG+P+A PP+G RRF PPE
Sbjct: 26 GGGVGAEGREDAELLVTVRGGRLRGIRLKTPG---GPVSAFLGIPFAEPPMGPRRFLPPE 82
Query: 89 APASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYV 148
W GV +ATT C Q + P + N E SEDCLYLN++
Sbjct: 83 PKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNREL--------SEDCLYLNVWT 134
Query: 149 PTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNM--FDGSVLAAYGN 206
P R PV+++++GG + G ++ +DG L
Sbjct: 135 PYP--------------------RPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAER 174
Query: 207 VIVATLNYRLGVLGFLST-GDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSG 265
++ ++NYR+G GFL+ G + A GN GLLDQ AL+W+ EN+A FGGDP +T+FG
Sbjct: 175 TVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGES 234
Query: 266 AGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV--NYQPLKYTRLLAAKVGC----DR 319
AGA+ V + +LS S GLF +A+ QSG W+ + + LA VGC
Sbjct: 235 AGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTG 294
Query: 320 EDSAEAVECLRRKPSRELVDQD----VQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLN 375
+ E V CLR +P++ LV+ + Q + + +F PVVDGD + D PE L+ G+F
Sbjct: 295 GNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHG 354
Query: 376 YDMLIGVNQGEGLKFVEDSA-----ESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRET 430
+L+GV + EG F+ A ++E +S + F V G P+ D+ E
Sbjct: 355 LQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVR------VGVPQVSDLAAEA 408
Query: 431 IKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAE 490
+ YTDW ++ R+ L + DH V P A A + VY Y F H
Sbjct: 409 VVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTL 468
Query: 491 GRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQP 550
P W HG E+ ++FG+P+ + N++ + + + +M YW NFA+TGDPN+
Sbjct: 469 SWPLWMGVPHGYEIEFIFGIPLDPSR-----NYTAEEKIFAQRLMRYWANFARTGDPNE- 522
Query: 551 VPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKP-RVRDNYRANKVAFWLELVPHLH 609
P+D K W + + +QY+ + L+P VR RA AFW +P L
Sbjct: 523 -PRDPK----------APQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKL- 570
Query: 610 NLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLP 650
L A+ P P G P P LP
Sbjct: 571 ------------LSATASEAPSTCPGFTHGEAAPRPGLPLP 599
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 301 bits (771), Expect = 2e-81
Identities = 198/599 (33%), Positives = 292/599 (48%), Gaps = 74/599 (12%)
Query: 30 GLGLGSLGEERFPVVNTAYG-RVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPE 88
G G+G+ G E ++ T G R+RG+R + GPV FLG+P+A PP+G RRF PPE
Sbjct: 26 GGGVGAEGREDAELLVTVRGGRLRGIRLKTPG---GPVSAFLGIPFAEPPMGPRRFLPPE 82
Query: 89 APASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYV 148
W GV +ATT C Q + P + N E SEDCLYLN++
Sbjct: 83 PKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNREL--------SEDCLYLNVWT 134
Query: 149 PTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNM--FDGSVLAAYGN 206
P R PV+++++GG + G ++ +DG L
Sbjct: 135 PYP--------------------RPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAER 174
Query: 207 VIVATLNYRLGVLGFLST-GDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSG 265
++ ++NYR+G GFL+ G + A GN GLLDQ AL+W+ EN+A FGGDP +T+FG
Sbjct: 175 TVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGES 234
Query: 266 AGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV--NYQPLKYTRLLAAKVGC----DR 319
AGA+ V + +LS S GLF +A+ QSG W+ + + LA VGC
Sbjct: 235 AGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTG 294
Query: 320 EDSAEAVECLRRKPSRELVDQD----VQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLN 375
+ E V CLR +P++ LV+ + Q + + +F PVVDGD + D PE L+ G+F
Sbjct: 295 GNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHG 354
Query: 376 YDMLIGVNQGEGLKFVEDSA-----ESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRET 430
+L+GV + EG F+ A ++E +S + F V G P+ D+ E
Sbjct: 355 LQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVR------VGVPQVSDLAAEA 408
Query: 431 IKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAE 490
+ YTDW ++ R+ L + DH V P A A + VY Y F H
Sbjct: 409 VVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTL 468
Query: 491 GRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQP 550
P W HG E+ ++FG+P+ + N++ + + + +M YW NFA+TGDPN+
Sbjct: 469 SWPLWMGVPHGYEIEFIFGIPLDPSR-----NYTAEEKIFAQRLMRYWANFARTGDPNE- 522
Query: 551 VPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKP-RVRDNYRANKVAFWLELVPHL 608
P+D K W + + +QY+ + L+P VR RA AFW +P L
Sbjct: 523 -PRDPK----------APQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKL 570
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 291 bits (746), Expect = 1e-78
Identities = 202/621 (32%), Positives = 297/621 (47%), Gaps = 87/621 (14%)
Query: 1 MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNN 60
MWL A L L+ + G P PVV+T +G+V G L
Sbjct: 1 MWLRAFILATLSASAAWAGHPSSP-----------------PVVDTVHGKVLGKFVSLEG 43
Query: 61 EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLP 120
PV FLG+P+A PPLG RF PP+ W V+NAT+ PP C Q+ +L
Sbjct: 44 -FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQ---LLS 99
Query: 121 VWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVM 180
FT+ E + SEDCLYLN+Y P + LTKK + PVM
Sbjct: 100 ELFTNRKENIPLKL---SEDCLYLNIYTPAD---LTKKN----------------RLPVM 137
Query: 181 LFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQ 240
+++HGG M G + +DG LAA+ NV+V T+ YRLG+ GF STGD+ ++GN+G LDQ+
Sbjct: 138 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 197
Query: 241 ALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV 300
ALRW+ +NIA FGG+P +TIFG AG V++L+LS ++ LF +AI++SG A++S V
Sbjct: 198 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLV 257
Query: 301 NYQPLK-YTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQ-----------PARYH 348
+K +A GC SA V CLR+K EL++ ++ P
Sbjct: 258 KKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQ 317
Query: 349 IAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDF 408
G V+DG ++ PE L + F ++G+N+ E + S
Sbjct: 318 PLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 377
Query: 409 TVSNFVDNLYGYP-EGKDVLRE-TIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVA 466
T + + Y K+++ E T K++ D+ ++ L L D + P+V
Sbjct: 378 TAMSLLWKSYPLVCIAKELIPEATEKYL----GGTDDTVKKKDLFLDLIADVMFGVPSVI 433
Query: 467 TAKLHADYQSPVYFYTFYHH--CQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFS 524
A+ H D +P Y Y F + ++ +P+ HGDEL VFG P + S
Sbjct: 434 VARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE------GAS 487
Query: 525 KNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHI 583
+ ++ LS +VM +W NFA+ G+PN + +P W ++N KE YL I
Sbjct: 488 EEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPEYNQKE-GYLQI 530
Query: 584 GLKPRVRDNYRANKVAFWLEL 604
G + + +VAFW L
Sbjct: 531 GANTQAAQKLKDKEVAFWTNL 551
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 291 bits (744), Expect = 2e-78
Identities = 203/621 (32%), Positives = 298/621 (47%), Gaps = 88/621 (14%)
Query: 1 MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNN 60
MWL A L L+ + G P P PVV+T +G+V G L
Sbjct: 1 MWLRAFILATLSASA------AWGHPSSP------------PVVDTVHGKVLGKFVSLEG 42
Query: 61 EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLP 120
PV FLG+P+A PPLG RF PP+ W V+NAT+ PP C Q+ +L
Sbjct: 43 -FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQ---LLS 98
Query: 121 VWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVM 180
FT+ E + SEDCLYLN+Y P + LTKK + PVM
Sbjct: 99 ELFTNRKENIPLKL---SEDCLYLNIYTPAD---LTKKN----------------RLPVM 136
Query: 181 LFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQ 240
+++HGG M G + +DG LAA+ NV+V T+ YRLG+ GF STGD+ ++GN+G LDQ+
Sbjct: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
Query: 241 ALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV 300
ALRW+ +NIA FGG+P +TIFG AG V++L+LS ++ LF +AI++SG A++S V
Sbjct: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLV 256
Query: 301 NYQPLK-YTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQ-----------PARYH 348
+K +A GC SA V CLR+K EL++ ++ P
Sbjct: 257 KKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQ 316
Query: 349 IAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDF 408
G V+DG ++ PE L + F ++G+N+ E + S
Sbjct: 317 PLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 409 TVSNFVDNLYGYP-EGKDVLRE-TIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVA 466
T + + Y K+++ E T K++ D+ ++ L L D + P+V
Sbjct: 377 TAMSLLWKSYPLVCIAKELIPEATEKYL----GGTDDTVKKKDLFLDLIADVMFGVPSVI 432
Query: 467 TAKLHADYQSPVYFYTFYHH--CQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFS 524
A+ H D +P Y Y F + ++ +P+ HGDEL VFG P + S
Sbjct: 433 VARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE------GAS 486
Query: 525 KNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHI 583
+ ++ LS +VM +W NFA+ G+PN + +P W ++N KE YL I
Sbjct: 487 EEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPEYNQKE-GYLQI 529
Query: 584 GLKPRVRDNYRANKVAFWLEL 604
G + + +VAFW L
Sbjct: 530 GANTQAAQKLKDKEVAFWTNL 550
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 290 bits (741), Expect = 5e-78
Identities = 203/628 (32%), Positives = 297/628 (47%), Gaps = 103/628 (16%)
Query: 1 MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNN 60
MWL A L L+ + G P P PVV+T +G+V G L
Sbjct: 1 MWLRAFILATLSASA------AWGHPSSP------------PVVDTVHGKVLGKFVSLEG 42
Query: 61 EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLP 120
PV FLG+P+A PPLG RF PP+ W V+NAT+ PP C Q+ +L
Sbjct: 43 -FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQ---LLS 98
Query: 121 VWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVM 180
FT+ E + SEDCLYLN+Y P + LTKK + PVM
Sbjct: 99 ELFTNRKENIPLKL---SEDCLYLNIYTPAD---LTKKN----------------RLPVM 136
Query: 181 LFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQ 240
+++HGG M G + +DG LAA+ NV+V T+ YRLG+ GF STGD+ ++GN+G LDQ+
Sbjct: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
Query: 241 ALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV 300
ALRW+ +NIA FGG+P +TIFG AG V++L+LS ++ LF +AI++SG A++S V
Sbjct: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLV 256
Query: 301 NYQPLK-YTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQ-----------PARYH 348
+K +A GC SA V CLR+K EL++ ++ P
Sbjct: 257 KKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQ 316
Query: 349 IAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGE---------GLKFVEDSAESED 399
G V+DG ++ PE L + F ++G+N+ E E + +
Sbjct: 317 PLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKT 376
Query: 400 GVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQ 459
+S + + L PE T K++ D+ ++ L L D
Sbjct: 377 AMSLLWKSYPLVCIAKEL--IPEA------TEKYL----GGTDDTVKKKDLFLDLIADVM 424
Query: 460 WVAPAVATAKLHADYQSPVYFYTFYHH--CQAEGRPEWADAAHGDELPYVFGVPMVGATD 517
+ P+V A+ H D +P Y Y F + ++ +P+ HGDEL VFG P +
Sbjct: 425 FGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE-- 482
Query: 518 LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVVWSKFNSK 576
S+ ++ LS +VM +W NFA+ G+PN + +P W ++N K
Sbjct: 483 ----GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPEYNQK 522
Query: 577 EKQYLHIGLKPRVRDNYRANKVAFWLEL 604
E YL IG + + +VAFW L
Sbjct: 523 E-GYLQIGANTQAAQKLKDKEVAFWTNL 549
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 286 bits (732), Expect = 5e-77
Identities = 198/575 (34%), Positives = 287/575 (49%), Gaps = 73/575 (12%)
Query: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
P+ T G+V G + G V FLG+P+A PPLG RF PPE P SW GVR+ TT
Sbjct: 96 PIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTT 154
Query: 102 LPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDE 161
P C Q+L + T ++ SEDCLYL++Y P
Sbjct: 155 HPAMCLQDLTAVESEFLSQFNMTFPSDS-------MSEDCLYLSIYTPAHS--------- 198
Query: 162 ATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGF 221
+ PVM+++HGG+ + G +++DGS+LAA NV+V + YRLGVLGF
Sbjct: 199 ----------HEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGF 248
Query: 222 LSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSE 281
STGD+ A GN+G LDQ+ ALRW+ +NIAHFGG+P+R+TIFG AG + V+ L++S S+
Sbjct: 249 FSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQ 308
Query: 282 GLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQD 341
GLF AI +SG A+ + + ++A CD+ DS V CLR K E++ +
Sbjct: 309 GLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAIN 368
Query: 342 VQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEG---LKFVEDSAESE 398
+P + VVDG +P P+ L+ +F ++GVN E + V +++
Sbjct: 369 -KPFK---MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQ 424
Query: 399 DGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALF--- 455
+ A + + L P D+LRE DNG+ +TL A F
Sbjct: 425 KEMDREASQAALQKMLTLLMLPPTFGDLLREEY--------IGDNGD--PQTLQAQFQEM 474
Query: 456 -TDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQ--AEGRPEWADAAHGDELPYVFGVPM 512
D +V PA+ A ++PVYFY F H RP A HGDELP+VF
Sbjct: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFF 533
Query: 513 VGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVVWS 571
G F++ + LS +M YW NFA+ G+PN + +P W
Sbjct: 534 GGNY----IKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----------------WP 573
Query: 572 KFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVP 606
F+ +E+QYL + L+P V +A+++ FW + +P
Sbjct: 574 LFD-QEEQYLQLNLQPAVGRALKAHRLQFWKKALP 607
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 282 bits (722), Expect = 8e-76
Identities = 196/582 (33%), Positives = 283/582 (48%), Gaps = 80/582 (13%)
Query: 42 PVVNTAYGRVRGVRRELNNEILGPVVQ-FLGVPYATPPLGARRFQPPEAPASWPGVRNAT 100
P V+T GRVRG R++ + +V FLG+P+A PPLG RF P W GVR+A+
Sbjct: 34 PEVDTTLGRVRG--RQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDAS 91
Query: 101 TLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRD 160
T PP C Q++ M F N + + SEDCL LN+Y P E
Sbjct: 92 TAPPMCLQDVES-----MNSSRFVLN---GKQQIFSVSEDCLVLNVYSPAE--------- 134
Query: 161 EATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLG 220
+ +PVM+++HGG+ + G +DGS LAAYG+V+V T+ YRLGVLG
Sbjct: 135 ----------VPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLG 184
Query: 221 FLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHS 280
F STGD+ A GN G LD + ALRW+ ENIA FGGD +T+FG AG S ++ L+LS +
Sbjct: 185 FFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVA 244
Query: 281 EGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQ 340
GLF +AI QSG + ++ P + +A + C AE V+CL++K ELV
Sbjct: 245 AGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-- 302
Query: 341 DVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVN---------QGEGLKFV 391
+ + + VDG V P P+ L+++ F + L+GVN +G GL
Sbjct: 303 -LSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDT 361
Query: 392 EDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTL 451
+ ED ++ S T DV E + + ++ ++ +
Sbjct: 362 MEQMSREDMLAISTPVLT-------------SLDVPPEMMPTVIDEYLGSNSDAQAKCQA 408
Query: 452 LALFTDHQWV-APAVATAKLHADYQSPVYFYTFYHHCQ--AEGRPEWADAAHGDELPYVF 508
F ++ P V+ ++ D SPV+FY F H A+ +P W A HG E +VF
Sbjct: 409 FQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVF 468
Query: 509 GVPMV---GATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNR 564
G P + + FP ++ + LS +M WT+FA+TGDPN + +P
Sbjct: 469 GGPFLMDESSRLAFP-EATEEEKQLSLTMMAQWTHFARTGDPNSKALPP----------- 516
Query: 565 FEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVP 606
W +FN E QYL I PR +R + FW E +P
Sbjct: 517 -----WPQFNQAE-QYLEINPVPRAGQKFREAWMQFWSETLP 552
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 280 bits (716), Expect = 4e-75
Identities = 242/817 (29%), Positives = 345/817 (42%), Gaps = 138/817 (16%)
Query: 44 VNTAYGRVRGVRRELNNEILGPVVQ-FLGVPYATPPLGARRFQPPEAPASWPGVRNATTL 102
V T G V GV ++L +LG V F G+P+A P + + P+ W G A
Sbjct: 29 VYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFAAP---TKALENPQPHPGWQGTLKAKNF 83
Query: 103 PPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQS---EDCLYLNLYVPTEDGPLTKKR 159
C Q AT Q+ + EDCLYLN++VP G R
Sbjct: 84 KKRCLQ----------------------ATITQDSTYGDEDCLYLNIWVP--QGRKQVSR 119
Query: 160 DEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGN--------MFDGSVLAAYGNVIVAT 211
D PVM++++GG+++ G+G+ ++DG +A GNVIV T
Sbjct: 120 D----------------LPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVT 163
Query: 212 LNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCV 271
NYR+G LGFLSTGD GNYGL DQ A+ W+ NIA FGGDP IT+FG AG + V
Sbjct: 164 FNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASV 223
Query: 272 NLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRR 331
+L LS +++GL ++AI+QSG A+S W + PL + + +A KVGC D+A +CL+
Sbjct: 224 SLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKV 283
Query: 332 KPSREL-------VDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQ 384
R L + P +++ F PV+DGD +P DP L ++Y + G N
Sbjct: 284 TDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDY--IAGTNN 341
Query: 385 GEGLKF--VEDSAESEDGVSASAFDF--TVSNFVDNLYGYPEGKDVLRETIKFMYTDWAD 440
+G F ++ A ++ + DF VS F +G + T WA
Sbjct: 342 MDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFT-----ITKGLRGAKTTFDVYTESWAQ 396
Query: 441 RDNGEMRRKTLLALFTDHQWVAPA-VATAKLHADYQS-PVYFYTFYHHCQAEGRPEWADA 498
+ E ++KT++ TD ++ P +A A+ A+ +S Y Y F H + P+W A
Sbjct: 397 DPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGA 456
Query: 499 AHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN---QPVPQDT 555
H D++ YVFG P P + D +S ++ YWTNFAKTGDPN VP
Sbjct: 457 DHADDIQYVFGKPFA-----TPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTH- 510
Query: 556 KFIHTKPNRFEEVVWSKFNSKEKQYLHIGLK---PRVRDNYRANKVAFWLELVPHLHNLH 612
W + ++ YL I K ++ + R N + +W + +L L
Sbjct: 511 --------------WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYW--TLTYL-ALP 553
Query: 613 TELFTTTTRLPPYA-TRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRD 671
T T +PP + P PP G T PP P P G P
Sbjct: 554 TVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDS 613
Query: 672 YSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPA 731
+ + T GA + PP G SG P P +
Sbjct: 614 GAPPVPPTGDSGAPPV--------------------------PPTGD-SGAPPVPPTGDS 646
Query: 732 AGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDY-TLALRRAPDDVPLLAPGALTL 790
+PP + + + G GA P A PP AP P GA +
Sbjct: 647 GAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPV 706
Query: 791 LPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLP 827
P+G P PP PP PPT S +P
Sbjct: 707 TPTGDSETAPVPPTG---DSGAPPVPPTGDSEAAPVP 740
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 276 bits (706), Expect = 6e-74
Identities = 195/588 (33%), Positives = 292/588 (49%), Gaps = 67/588 (11%)
Query: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
P NT G ++G + + + PV FLGVP+A PPLG+ RF P+ + W +R AT+
Sbjct: 31 PQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATS 89
Query: 102 LPPACPQNLHGAL-PAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRD 160
P C QN L ML V + SEDCLYLN+Y P
Sbjct: 90 YPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSEDCLYLNIYAPAH--------- 131
Query: 161 EATLNPPDTDIRDPGKK-PVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVL 219
D G K PV+++ GG++ G+ ++FDGS LAAY +V+V + YRLG+
Sbjct: 132 -----------ADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF 180
Query: 220 GFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHH 279
GF +T DQ A GN+ DQ+ AL W+ +NI FGGDP +TIFG AGA V+ LILS
Sbjct: 181 GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM 240
Query: 280 SEGLFQKAIAQSGTAISSW--SVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSREL 337
++GLF KAI +SG AI + + +Y+ + +++A G + DS + CLR KPS+EL
Sbjct: 241 AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL 300
Query: 338 VDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAES 397
+ + +F VVDG P++P L+ Q F +IGVN E F+ E+
Sbjct: 301 LTLSQKTK----SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPMKEA 355
Query: 398 EDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTD 457
+ +S S + + L+ P+ ++ + D+ + R +LL L D
Sbjct: 356 PEILSGSNKSLALHLIQNILHIPPQYLHLVANEY------FHDKHSLTEIRDSLLDLLGD 409
Query: 458 HQWVAPAVATAKLHADYQSPVYFYTFYH--HCQAEGRPEWADAAHGDELPYVFGVPMVGA 515
+V PA+ TA+ H D +PVYFY F H C + +P + A H DE+ +VFG +
Sbjct: 410 VFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKG 469
Query: 516 TDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNS 575
+ ++ + +LS +M YW FA+TG+PN + +W +N
Sbjct: 470 DIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPAYNL 514
Query: 576 KEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHN----LHTELFTTT 619
E QYL + L + + +V FW +P + + LH+ L + T
Sbjct: 515 TE-QYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASDMLHSPLSSLT 561
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 269 bits (688), Expect = 7e-72
Identities = 190/573 (33%), Positives = 281/573 (49%), Gaps = 85/573 (14%)
Query: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
P+ T G+V G + G V FLG+P+A PPLG RF PPE P SW GVR+ TT
Sbjct: 96 PIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTT 154
Query: 102 LPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDE 161
P C Q+L + T ++ SEDCLYL++Y P
Sbjct: 155 HPAMCLQDLTAVESEFLSQFNMTFPSDS-------MSEDCLYLSIYTPAHS--------- 198
Query: 162 ATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGF 221
+ PVM+++HGG+ + G +++DGS+LAA NV+V + YRLGVLGF
Sbjct: 199 ----------HEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGF 248
Query: 222 LSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSE 281
STGD+ A GN+G LDQ+ ALRW+ +NIAHFGG+P+R+TIFG AG + V+ L++S S+
Sbjct: 249 FSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQ 308
Query: 282 GLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQD 341
GLF AI +SG A+ + + ++A CD+ DS V CLR K E++ +
Sbjct: 309 GLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAIN 368
Query: 342 VQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEG---LKFVEDSAESE 398
+P + VVDG +P P+ L+ +F ++GVN E + V +++
Sbjct: 369 -KPFK---MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQ 424
Query: 399 DGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALF--- 455
+ A + + L P D+LRE DNG+ +TL A F
Sbjct: 425 KEMDREASQAALQKMLTLLMLPPTFGDLLREEY--------IGDNGD--PQTLQAQFQEM 474
Query: 456 -TDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVG 514
D +V PA+ A ++PVYFY F H +P W P +
Sbjct: 475 MADSMFVIPALQVAHFQCS-RAPVYFYEFQH------QPSWLKNIR---------PPHMK 518
Query: 515 ATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVVWSKF 573
A + F++ + LS +M YW NFA+ G+PN + +P W F
Sbjct: 519 ADHV---KFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----------------WPLF 559
Query: 574 NSKEKQYLHIGLKPRVRDNYRANKVAFWLELVP 606
+ +E+QYL + L+P V +A+++ FW + +P
Sbjct: 560 D-QEEQYLQLNLQPAVGRALKAHRLQFWKKALP 591
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 254 bits (648), Expect = 3e-67
Identities = 182/593 (30%), Positives = 268/593 (45%), Gaps = 153/593 (25%)
Query: 33 LGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPAS 92
LG+L +R P V T YG ++G + + P+ FLGVP++ PPLG RF PPE P
Sbjct: 19 LGALHTKR-PQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRPPLGILRFAPPEPPEP 74
Query: 93 WPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQ--------SEDCLYL 144
W G+R+ATT PP C Q G L A+ YV + SEDCLYL
Sbjct: 75 WKGIRDATTYPPGCLQESWGQL---------------ASMYVSTRERYKWLRFSEDCLYL 119
Query: 145 NLYVPTEDGPLTKKRDEATLNPPDTDIRDPG--KKPVMLFLHGGSYMEGTGNMFDGSVLA 202
N+Y P R PG + PVM++ GG+++ G + ++GS LA
Sbjct: 120 NVYAPA---------------------RAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLA 158
Query: 203 AYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIF 262
A V++ L +RLG+ GFLST D A+GN+GLLDQ+ ALRW+ ENIA FGGDP +T+F
Sbjct: 159 AREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLF 218
Query: 263 GSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDS 322
G AGA ++ L++S + GLF +AI+QSGTA+ + PLK + +A GC+ +
Sbjct: 219 GQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNST 278
Query: 323 AEAVECLRRKPSRELV-----------DQDVQPARYHIAFGPVVDGDVVPDDPEILMQQG 371
V CLR +++ + P + PVVDG V+PDDP +L+ QG
Sbjct: 279 QILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQG 338
Query: 372 EFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETI 431
+ + L+GVN +E + ++ V ++DN+ +
Sbjct: 339 KVSSVPYLLGVNN------LEFNWLLPYNITKEQVPLVVEEYLDNVNEH----------- 381
Query: 432 KFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEG 491
DW +M R ++ + D +V + TA YH + G
Sbjct: 382 -----DW------KMLRNRMMDIVQDATFVYATLQTAH--------------YHRGLSMG 416
Query: 492 RPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 551
+ + LS +M YW NFA+TG+PN
Sbjct: 417 KEK----------------------------------ALSLQMMKYWANFARTGNPNDG- 441
Query: 552 PQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLEL 604
W ++N K+++YL + RV + K+AFW+ L
Sbjct: 442 --------------NLPCWPRYN-KDEKYLQLDFTTRVGMKLKEKKMAFWMSL 479
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 230 bits (587), Expect = 4e-60
Identities = 181/586 (30%), Positives = 270/586 (46%), Gaps = 113/586 (19%)
Query: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
P NT G ++G + + + PV FLGVP+A PPLG+ RF P+ + W +R AT+
Sbjct: 31 PQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATS 89
Query: 102 LPPACPQNLHGAL-PAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRD 160
P C QN L ML V + SEDCLYLN+Y P
Sbjct: 90 YPNLCLQNSEWLLLDQHMLKVHYPKF---------GVSEDCLYLNIYAPAH--------- 131
Query: 161 EATLNPPDTDIRDPGKK-PVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVL 219
D G K PV+++ GG++ G+ ++FDGS LAAY +V+V + YRLG+
Sbjct: 132 -----------ADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIF 180
Query: 220 GFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHH 279
GF +T DQ A GN+ DQ+ AL W+ +NI FGGDP +TIFG AGA V+ LILS
Sbjct: 181 GFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPM 240
Query: 280 SEGLFQKAIAQSGTAISSW--SVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSREL 337
++GLF KAI +SG AI + + +Y+ + +++A G + DS + CLR KPS+EL
Sbjct: 241 AKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKEL 300
Query: 338 VDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAES 397
+ + +F VVDG P++P L+ Q F +IGVN E F+ E+
Sbjct: 301 LTLSQKTK----SFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE-CGFLLPMKEA 355
Query: 398 EDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTD 457
+ +S S + + L+ P+ ++ + D+ + R +LL L D
Sbjct: 356 PEILSGSNKSLALHLIQNILHIPPQYLHLVANEY------FHDKHSLTEIRDSLLDLLGD 409
Query: 458 HQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATD 517
+V PA+ TA+ H + GAT+
Sbjct: 410 VFFVVPALITARYHRE----------------------------------------GATE 429
Query: 518 LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKE 577
+ +LS +M YW FA+TG+PN + +W +N E
Sbjct: 430 --------EEKLLSRKMMKYWATFARTGNPNGN---------------DLSLWPAYNLTE 466
Query: 578 KQYLHIGLKPRVRDNYRANKVAFWLELVPHLHN----LHTELFTTT 619
QYL + L + + +V FW +P + + LH+ L + T
Sbjct: 467 -QYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASDMLHSPLSSLT 511
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 189 bits (481), Expect = 7e-48
Identities = 157/539 (29%), Positives = 242/539 (44%), Gaps = 71/539 (13%)
Query: 29 PGLGLGSLGEERFPVVNTAYGRVRGVRRELN-NEILGPVVQFLGVPYATPPLGARRFQPP 87
PG+ L S V + +GR+ G + + V QFLGVPYA PPL RRFQ P
Sbjct: 2187 PGISLLSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAP 2246
Query: 88 EAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLY 147
E P +W G +A+ +C W + + V SEDCLYLN++
Sbjct: 2247 E-PLNWTGSWDASKPRASC---------------WQPGTRTSTSPGV---SEDCLYLNVF 2287
Query: 148 VPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNM--FDGSVLAAYG 205
+P P V++F H E + DGS LAA G
Sbjct: 2288 IPQNVAP---------------------NASVLVFFHNTMDREESEGWPAIDGSFLAAVG 2326
Query: 206 NVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFG-- 263
N+IV T +YR+GV GFLS+G GN+GLLDQ+ AL W+ +I FGGDP R+++
Sbjct: 2327 NLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADR 2386
Query: 264 SGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV--NYQPLKYTRLLAAKVGCDRED 321
GA + ++LL + LF++A+ G+A+S +V + + + LA +V C
Sbjct: 2387 GGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSS 2446
Query: 322 SAEAVECLRRKPSRELVDQDVQ------PARYHIAFGPVVDGDVVPDDPEILMQQGEFLN 375
S E V CLR+KP+ L D + P Y +GPV+DG + + P +++ ++
Sbjct: 2447 SQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY---WGPVIDGHFLREPPARALKRSLWVE 2503
Query: 376 YDMLIGVNQGEGL----KFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETI 431
D+LIG +Q +GL K V+ ES S+ + + N G + +
Sbjct: 2504 VDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQA---LQNSLGGEDSDARVEAAA 2560
Query: 432 KFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEG 491
+ Y+ D+ + L D+ + P + A A F YH + G
Sbjct: 2561 TWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVF--MYHAPENYG 2618
Query: 492 RPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQP 550
A ++ + G+P A + FS + LS +M Y+++F ++G+PN P
Sbjct: 2619 HGSLELLA---DVQFALGLPFYPA---YEGQFSLEEKSLSLKIMQYFSHFIRSGNPNYP 2671
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 153 bits (386), Expect = 7e-37
Identities = 104/291 (35%), Positives = 155/291 (53%), Gaps = 17/291 (5%)
Query: 185 GGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRW 244
GG++ G+ ++FDGS LAAY +++V + YRLG+ GF +T DQ A GN+ DQ+ AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 245 LSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSW--SVNY 302
+ +NI FGGDP +TIFG GA V+ LILS +EGLF KA+ +SG AI + + +Y
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 303 QPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPD 362
+ + +++A G + DS + CLR K S+EL+ + AF VVDG P+
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK----AFTQVVDGAFFPN 195
Query: 363 DPEILMQQGEFLNYDMLIGVNQGE-GLKF-VEDSAESEDGVSASAFDFTVSNFVDNLYGY 420
+P L+ Q F +IGVN E G ++++ E G + S N + L Y
Sbjct: 196 EPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGSNKSLALCLTQNILHILPNY 255
Query: 421 PEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLH 471
+ Y + D+ + R +LL L D +V P + TA+ H
Sbjct: 256 -------LHLVAGEY--FHDKHSLTEIRDSLLDLLGDVFFVIPKLITAQYH 297
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 152 bits (384), Expect = 1e-36
Identities = 103/291 (35%), Positives = 155/291 (53%), Gaps = 17/291 (5%)
Query: 185 GGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRW 244
GG++ G+ ++FDGS LAAY +++V + YRLG+ GF +T DQ A GN+ DQ+ AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 245 LSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSW--SVNY 302
+ +NI FGGDP +TIFG GA V+ L+LS +EGLF KA+ +SG AI + + +Y
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 303 QPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPD 362
+ + +++A G + DS + CLR K S+EL+ + AF VVDG P+
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK----AFTQVVDGAFFPN 195
Query: 363 DPEILMQQGEFLNYDMLIGVNQGE-GLKF-VEDSAESEDGVSASAFDFTVSNFVDNLYGY 420
+P L+ Q F +IGVN E G ++++ E G + S N + L Y
Sbjct: 196 EPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGSNKSLALCLTQNILHILPNY 255
Query: 421 PEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLH 471
+ Y + D+ + R +LL L D +V P + TA+ H
Sbjct: 256 -------LHLVAGEY--FHDKHSLTEIRDSLLDLLGDVFFVIPKLITARYH 297
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 93.2 bits (230), Expect = 9e-19
Identities = 41/84 (48%), Positives = 59/84 (70%)
Query: 179 VMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQ 238
V+L+ GG++ G+ ++FDGS LAAY +++V + YRLG+ GF +T DQ A GN+ DQ
Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79
Query: 239 IQALRWLSENIAHFGGDPERITIF 262
+ AL W+ +NI FGGDP +TIF
Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIF 103
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 57.8 bits (138), Expect = 4e-08
Identities = 78/248 (31%), Positives = 85/248 (34%), Gaps = 67/248 (27%)
Query: 585 LKPRVRD--NYRANKVAFWLELVPHLHNLHTELFTTTTRLPPY----ATRWPPRPPAGAP 638
L R+RD N K+A EL L EL T R A+R PP P P
Sbjct: 411 LTERLRDAENESMAKIA---ELEKQLSQARKELETLRERFSESTAMGASRRPPEPEKAPP 467
Query: 639 GTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALY 698
P L E E G R PGD+ L V VA
Sbjct: 468 AAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEI-LPVAVA----------------- 509
Query: 699 YKRDRRQELRCRRLSPPGGSGS--GVPGGGP---LLPAA----GRELPPEEELVSLQLKR 749
+P GG GVP G P L PAA G PP L L
Sbjct: 510 --------------TPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLP--- 552
Query: 750 GGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPF 809
P EA P P L +P+ P AP LP L PPPPPPPP
Sbjct: 553 ------SPQEA--PPSAPPQAPPLPGSPEPPP--APP----LPGDLPPPPPPPPPPPGTD 598
Query: 810 GPFPPPPP 817
GP PPPPP
Sbjct: 599 GPVPPPPP 606
Score = 37.0 bits (84), Expect = 0.076
Identities = 20/43 (46%), Positives = 20/43 (46%), Gaps = 5/43 (11%)
Query: 622 LPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDR 664
LPP PP PP PGT P PP PP P P P A R
Sbjct: 584 LPP-----PPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGR 621
Score = 30.0 bits (66), Expect = 9.3
Identities = 16/39 (41%), Positives = 17/39 (43%), Gaps = 11/39 (28%)
Query: 630 PPRPPAGAPGTRRPPPP---------ATLPPEPEPEPGP 659
PP PP PG PPPP +PP P P P P
Sbjct: 575 PPAPPL--PGDLPPPPPPPPPPPGTDGPVPPPPPPPPPP 611
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 53.1 bits (126), Expect = 1e-06
Identities = 42/109 (38%), Positives = 47/109 (43%), Gaps = 13/109 (11%)
Query: 714 PPGGSGSGVPGGGPL--LPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTL 771
PP + VPG PL LP+A PE L L+ PA +P PP
Sbjct: 1422 PPLAPAAAVPGPPPLPGLPSANSNGTPEPPL----LEEKPPPTPPPAPTPQPQPPPPPPP 1477
Query: 772 ALRRAPDDVPLLAPGALTLLPSGLGPPP-PPPPPSLHPFGPFPPPPPTA 819
P PL+AP PS PPP PPPPP P P PPPPP A
Sbjct: 1478 PQPALPSPPPLVAP-----TPSSPPPPPLPPPPPPAMP-SPPPPPPPAA 1520
Score = 44.3 bits (103), Expect = 5e-04
Identities = 40/119 (33%), Positives = 43/119 (36%), Gaps = 11/119 (9%)
Query: 714 PP--GGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPA-EALRPACPPDYT 770
PP G + P G PL PAA PP L L G P E P PP
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPP--LPGLPSANSNGTPEPPLLEEKPPPTPPPAP 1465
Query: 771 LALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHP 829
+ P P P AL P + P P PPP P PPPPP A P P
Sbjct: 1466 TPQPQPPPPPPPPQP-ALPSPPPLVAPTPSSPPPP-----PLPPPPPPAMPSPPPPPPP 1518
Score = 38.1 bits (87), Expect = 0.034
Identities = 29/99 (29%), Positives = 37/99 (37%), Gaps = 13/99 (13%)
Query: 718 SGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGAD-PAEALRPACPPDYTLALRRA 776
+G+G P G P G P R G G + P L P PP+ +
Sbjct: 976 AGAGPPPGPPAYDPYGPYCPG----------RASGAGPETPGLGLDPNKPPELPSTVNAE 1025
Query: 777 PDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPP 815
P + L+ G P PPPPPP P+ P G P
Sbjct: 1026 P--LGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
Score = 35.0 bits (79), Expect = 0.29
Identities = 16/37 (43%), Positives = 16/37 (43%)
Query: 623 PPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGP 659
PP P PP AP PPPP PP P P P
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512
Score = 34.3 bits (77), Expect = 0.49
Identities = 38/112 (33%), Positives = 44/112 (39%), Gaps = 28/112 (25%)
Query: 725 GGPLLPAAGRELPPEEELVSLQLKRGGGVGADPA--EALRPACP-------PDYTLALRR 775
GG G+ PPE+E K G G P + P CP P+ T L
Sbjct: 955 GGGAADDYGKAGPPEDEG---DPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE-TPGLGL 1010
Query: 776 APDDVPLLAPGALTLLPSGL---GP---PPPPPPPSLHPFGPFPPPPPTATS 821
P+ P L P + P GL GP PPPPPP PPPPP S
Sbjct: 1011 DPNKPPEL-PSTVNAEPLGLIQSGPHQAAPPPPPP--------PPPPPAPAS 1053
Score = 33.1 bits (74), Expect = 1.1
Identities = 53/209 (25%), Positives = 72/209 (34%), Gaps = 50/209 (23%)
Query: 655 PEPGPRA---YDRFPGDSRDYS------TELSVTVAVGASLLFLNILAFAALYYKRD--- 702
P+PGP A +F S + TEL ++ A+ S F + A +A +
Sbjct: 100 PQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGS 159
Query: 703 ------RRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGV--- 753
L+ SPP +G+ +L + P + + GGGV
Sbjct: 160 RPFPVPSSLSLQDPPFSPPA---NGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGP 216
Query: 754 -GADPAEA--LRPACPPDYTLALRRAPDDVPLLAPGALTLLP-----------SGLGPPP 799
G PA+ RP PPD R P LLA + SG P P
Sbjct: 217 AGLGPAQTPPYRPG-PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP 275
Query: 800 PPPPPSL-----------HPFGPFPPPPP 817
PPP +L P PPPPP
Sbjct: 276 PPPERALPRQDTVIKHYQRPASAQPPPPP 304
Score = 33.1 bits (74), Expect = 1.1
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 5/35 (14%)
Query: 630 PPRPPAGAPGTRRPP-----PPATLPPEPEPEPGP 659
P P A + GT PP PP T PP P P+P P
Sbjct: 1437 PGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQP 1471
Score = 33.1 bits (74), Expect = 1.1
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 1/38 (2%)
Query: 623 PPYATRWPPRPPAGAPGTRRPPPPATLPPEPE-PEPGP 659
PP PP P AP + PPP PP+P P P P
Sbjct: 1450 PPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPP 1487
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/37 (43%), Positives = 18/37 (48%), Gaps = 5/37 (13%)
Query: 630 PPRPPAGAPGTRRPPP-----PATLPPEPEPEPGPRA 661
PP PP P PPP P++ PP P P P P A
Sbjct: 1472 PPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPA 1508
Score = 32.0 bits (71), Expect = 2.4
Identities = 15/34 (44%), Positives = 15/34 (44%), Gaps = 4/34 (11%)
Query: 630 PPRPPAGAPGTRRPPPPA----TLPPEPEPEPGP 659
PP PP P PPPPA PPE P P
Sbjct: 1502 PPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Score = 31.6 bits (70), Expect = 3.2
Identities = 23/67 (34%), Positives = 25/67 (37%), Gaps = 12/67 (17%)
Query: 754 GADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLP----SGLGPPPPPPPPSLHPF 809
G D L P P L AP P + + LL G PPPPPPP
Sbjct: 787 GPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPP----- 841
Query: 810 GPFPPPP 816
PPPP
Sbjct: 842 ---PPPP 845
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 52.8 bits (125), Expect = 1e-06
Identities = 43/127 (33%), Positives = 48/127 (37%), Gaps = 12/127 (9%)
Query: 713 SPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLA 772
+PP GS G G PA PP + G G P P+ PP A
Sbjct: 303 APPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFA 362
Query: 773 LRRAPD-----DVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPP-TATSHNNTL 826
P D P L P L+ G PPPPPPPP P PPPPP T +
Sbjct: 363 APPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPP------PGPPPPPFTGADGQPAI 416
Query: 827 PHPHSTT 833
P P S T
Sbjct: 417 PPPLSDT 423
Score = 43.5 bits (101), Expect = 8e-04
Identities = 35/117 (29%), Positives = 42/117 (35%), Gaps = 14/117 (11%)
Query: 714 PPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGV-GADPAEALRPACPPDYTLA 772
PP P PP E + +RG G+ G + + P+ PP
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPP---- 302
Query: 773 LRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHP 829
AP PL +P G PPP PPPP G PPPPP T P P
Sbjct: 303 ---AP---PLGSPPGPK---PGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPP 350
Score = 38.5 bits (88), Expect = 0.026
Identities = 21/48 (43%), Positives = 24/48 (50%), Gaps = 7/48 (14%)
Query: 623 PPYATRWPPRPPAG--APGTRRPPPPATLPPEPE-----PEPGPRAYD 663
PP PP PP G +PGT PP P + PP P+ P P P A D
Sbjct: 327 PPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAAD 374
Score = 36.6 bits (83), Expect = 0.099
Identities = 19/44 (43%), Positives = 20/44 (45%), Gaps = 7/44 (15%)
Query: 623 PPYATRWPPRPPAGAPGTRRPPPP-------ATLPPEPEPEPGP 659
P +A PP PP A PPPP A PP P P PGP
Sbjct: 359 PDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGP 402
Score = 33.9 bits (76), Expect = 0.64
Identities = 18/38 (47%), Positives = 19/38 (50%), Gaps = 3/38 (7%)
Query: 623 PPYATRWP--PRPPAGAP-GTRRPPPPATLPPEPEPEP 657
PP A +P P PP P G PPPP PP P P P
Sbjct: 369 PPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/45 (42%), Positives = 21/45 (46%), Gaps = 7/45 (15%)
Query: 630 PPRPPAGAPGTRRP---PPPATLPPEPE----PEPGPRAYDRFPG 667
PP PP G+P +P PPPA PP P P P P PG
Sbjct: 301 PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPG 345
Score = 32.7 bits (73), Expect = 1.4
Identities = 18/39 (46%), Positives = 20/39 (51%), Gaps = 5/39 (12%)
Query: 623 PPYATRWPPRPPAGAPGTRRPPPPA----TLPPEPEPEP 657
PP +PP P AP PPPPA TLPP P +P
Sbjct: 349 PPSPPSFPPHPDFAAPPPP-PPPPAADYPTLPPPPLSQP 386
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 52.4 bits (124), Expect = 2e-06
Identities = 60/222 (27%), Positives = 76/222 (34%), Gaps = 55/222 (24%)
Query: 630 PPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFL 689
P PP P + PPPP P P GP D++ G + VG+ +
Sbjct: 417 PNGPPP--PWMQPPPPPMNQGPHPPGHHGPPPMDQYLGST-----------PVGSGVY-- 461
Query: 690 NILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPG---GGPLLPAAGREL------PPEE 740
L+ + + PP SG P GPL P ++ PP
Sbjct: 462 ------RLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSS 515
Query: 741 ELVS----------LQLKRGGGVGADP-------AEALRPACPPDYTLALRRAPDDVPLL 783
+ S G G+ P A A P P ++ P VPL
Sbjct: 516 SMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQ-----MQGNPTMVPL- 569
Query: 784 APGALTLLPSGLGPPPPPPPPSL--HPFGPFPPPPPTATSHN 823
PG LP G PPPPPPPP + P PPPPP N
Sbjct: 570 PPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSN 611
Score = 46.2 bits (108), Expect = 1e-04
Identities = 52/197 (26%), Positives = 66/197 (33%), Gaps = 62/197 (31%)
Query: 630 PPRPPAGAPGTRRPPPPATLPP----EPEPEPGPRAYDRFPGDSRDYSTEL-------SV 678
PP PP+G P PPP LPP + +P P P P S ST L +
Sbjct: 481 PPPPPSGQPP---PPPSGPLPPWQQQQQQPPPPPP-----PSSSMASSTPLPWQQNTTTT 532
Query: 679 TVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPP 738
T + G + +Q+ SP G P PL P LPP
Sbjct: 533 TTSAGTGSI-------------PPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP 579
Query: 739 EEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVP-----------LLAPGA 787
GA P P PP + + AP P ++ G
Sbjct: 580 ---------------GAPPP----PPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGV 620
Query: 788 LTLLPSGLGPPPPPPPP 804
+ P G+ P PPPPPP
Sbjct: 621 AGMPPFGMPPAPPPPPP 637
Score = 40.4 bits (93), Expect = 0.007
Identities = 44/149 (29%), Positives = 52/149 (34%), Gaps = 44/149 (29%)
Query: 717 GSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGG-----GVGADPAEALRPACPP---- 767
G G G PGGGP P L SL GG P ++P PP
Sbjct: 384 GGGPGGPGGGP------HSFP--HPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQG 435
Query: 768 ------------DYTLALRRAPDDVPLL--APGALTLLPSGLGPPPPPPP---PSLHPFG 810
D L V L G + P G+ PPPPPPP P P G
Sbjct: 436 PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSG 495
Query: 811 PF----------PPPPPTATSHNNTLPHP 829
P PPPPP ++S ++ P P
Sbjct: 496 PLPPWQQQQQQPPPPPPPSSSMASSTPLP 524
Score = 34.3 bits (77), Expect = 0.49
Identities = 17/36 (47%), Positives = 19/36 (52%), Gaps = 3/36 (8%)
Query: 622 LPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEP 657
LPP A PP PP G+ G PPP PP P +P
Sbjct: 577 LPPGAPPPPPPPPPGSAGMMYAPPP---PPPPPMDP 609
Score = 31.6 bits (70), Expect = 3.2
Identities = 35/118 (29%), Positives = 45/118 (38%), Gaps = 19/118 (16%)
Query: 717 GSGSGVPGGGPLL----PAAGRELPPEEELVSLQLKRGGGVGADPAEA-----LRPACPP 767
GS SG P PL PAA PP L+S R + + P+E+ + P
Sbjct: 330 GSTSG-PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPG 388
Query: 768 DYTLALRRAPDDVPLLAPG----ALTLLPSG-----LGPPPPPPPPSLHPFGPFPPPP 816
P +P L G + P+G + PPPPP HP G PPP
Sbjct: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPP 446
Score = 31.2 bits (69), Expect = 4.2
Identities = 25/66 (37%), Positives = 30/66 (45%), Gaps = 11/66 (16%)
Query: 618 TTTRLPPYATRWPPRPPAGAPGTRRPPPP--ATLPPEPEPEPGPRAYDRFPGDSRDYSTE 675
T LPP PP PP GAP PPPP A + P P P P P D ++ T
Sbjct: 565 TMVPLPPGVQ--PPLPP-GAPPPPPPPPPGSAGMMYAPPPPPPP------PMDPSNFVTM 615
Query: 676 LSVTVA 681
+ + VA
Sbjct: 616 MGMGVA 621
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 52.0 bits (123), Expect = 2e-06
Identities = 64/198 (32%), Positives = 71/198 (35%), Gaps = 50/198 (25%)
Query: 631 PRPPAGAPGTRRPPPPATLPPEPEPEPG----PRAYDRFPGDSRDYSTELSVTVAVGASL 686
P PP PG P P+T P+P P G P PG L GA +
Sbjct: 877 PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLP-----GAGI 931
Query: 687 LFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQ 746
L L L A + PP G+ +P P LP AG LPP
Sbjct: 932 LPLPPLPGAGI--------------PPPPPLPGAAIPPPPP-LPGAGIPLPPPLP----- 971
Query: 747 LKRGGGVGADPAEALRPA-CPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPP----- 800
G G P L A PP L P PL PGA G+ PPPP
Sbjct: 972 -----GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGA------GIPPPPPLPGAG 1018
Query: 801 -PPPPSLHPFGPFPPPPP 817
PPPP L P PPPPP
Sbjct: 1019 IPPPPPL-PGAGIPPPPP 1035
Score = 48.9 bits (115), Expect = 2e-05
Identities = 66/200 (33%), Positives = 72/200 (36%), Gaps = 53/200 (26%)
Query: 630 PPRPPAGAPGTRRPPPP-----ATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGA 684
PP PP PG PPPP PP P P G PG L GA
Sbjct: 1009 PPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-----GA 1061
Query: 685 SLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVS 744
+ L A + PP G+G+P PL P AG +PP L
Sbjct: 1062 GIPPPPPLPGAGIP--------------PPPPLPGAGIPPPPPL-PGAG--IPPPPPLP- 1103
Query: 745 LQLKRGGGVGADPAEALRPA-CPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPP--- 800
GVG P L A PP L P PL PGA G+ PPPP
Sbjct: 1104 -------GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGA------GIPPPPPLPR 1148
Query: 801 ---PPPPSLHPFGPFPPPPP 817
PPPP L P PPPPP
Sbjct: 1149 VGIPPPPPL-PGAGIPPPPP 1167
Score = 48.1 bits (113), Expect = 3e-05
Identities = 67/210 (31%), Positives = 74/210 (35%), Gaps = 51/210 (24%)
Query: 623 PPYATRWPPRPPAGAPGTRRPPPP-----ATLPPEPEPEPGPRAYDRFPGDSRDYSTELS 677
P T P PP PG PPPP LP P P G PG + L
Sbjct: 901 PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP 960
Query: 678 VTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELP 737
GA + L A + PP G+G+P PL P AG +P
Sbjct: 961 -----GAGIPLPPPLPGAGIP--------------PPPPLPGAGIPPPPPL-PGAG--IP 998
Query: 738 PEEELVSLQLKRGGGVGADPAEALRPA-CPPDYTLALRRAPDDVPLLAPGALTLLPSGLG 796
P L G G P L A PP L P PL PGA G+
Sbjct: 999 PPPPLP--------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGA------GIP 1042
Query: 797 PPPP------PPPPSLHPFG-PFPPPPPTA 819
PPPP PPPP L G P PPP P A
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1072
Score = 42.7 bits (99), Expect = 0.001
Identities = 60/210 (28%), Positives = 65/210 (30%), Gaps = 59/210 (28%)
Query: 630 PPRPPAGAPGTRRPPPP-----ATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGA 684
PP PP PG PPPP PP P P G PG L
Sbjct: 1097 PPPPPL--PGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP------- 1147
Query: 685 SLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVS 744
R PP G+G+P PL P AG +PP L
Sbjct: 1148 -----------------------RVGIPPPPPLPGAGIPPPPPL-PGAG--IPPPPPLP- 1180
Query: 745 LQLKRGGGVGADPAEALRPA-CPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPP 803
GVG P L PP L P PL G+G PP P P
Sbjct: 1181 -------GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL----------PGMGIPPAPAP 1223
Query: 804 PSLHPFGPFPPPPPTATSHNNTLPHPHSTT 833
P P PPPP S LP S+T
Sbjct: 1224 PLPPPGTGIPPPPLLPVSGPPLLPQVGSST 1253
Score = 41.2 bits (95), Expect = 0.004
Identities = 52/191 (27%), Positives = 63/191 (32%), Gaps = 42/191 (21%)
Query: 643 PPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRD 702
PPPP+ L + +PG + STE + S F N
Sbjct: 811 PPPPSLLWSAGQGQPGSQP-------PHSISTEFQTSHEHSVSSAFKN------------ 851
Query: 703 RRQELRCRRLSPPG----GSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPA 758
C SPP S S +PG G + P PP + L P
Sbjct: 852 -----SCNIPSPPPLPCTESSSSMPGLGMVPPPP----PPLPGMTVPTLPSTAIPQPPPL 902
Query: 759 EALRPACPPDYTLALRRAPDDVPLLAPGALTLLP---SGLGPPPP-------PPPPSLHP 808
+ PP L P PL G L L P +G+ PPPP PPPP
Sbjct: 903 QGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA 962
Query: 809 FGPFPPPPPTA 819
P PPP P A
Sbjct: 963 GIPLPPPLPGA 973
Score = 38.5 bits (88), Expect = 0.026
Identities = 49/198 (24%), Positives = 64/198 (32%), Gaps = 34/198 (17%)
Query: 634 PAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILA 693
P G PP LP P PG + G + +E+S+ V+
Sbjct: 748 PTEEGGVLTLPPVDGLPGRPPCPPGAES-----GPQTKFCSEISLIVSP----------- 791
Query: 694 FAALYYKRDRRQELRCRRLSPPGGS-----GSGVPGGGPLLPAAGRELPPEEELVSLQLK 748
+ + D Q + PP S G G PG P + E VS K
Sbjct: 792 -RRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFK 850
Query: 749 RGGGVGADPAEALRPACPPDYTL-ALRRAPDDVPLLAPGALTLLPSGLGPPPPP------ 801
+ + P P ++ L P P L + LPS P PPP
Sbjct: 851 NSCNIPSPPP---LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEM 907
Query: 802 --PPPSLHPFGPFPPPPP 817
PPP P PPPPP
Sbjct: 908 LPPPPPPLPGAGIPPPPP 925
>gi|28872794 CCAAT/enhancer binding protein alpha [Homo sapiens]
Length = 358
Score = 50.8 bits (120), Expect = 5e-06
Identities = 60/209 (28%), Positives = 81/209 (38%), Gaps = 41/209 (19%)
Query: 630 PPRPPAGAP-GTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLF 688
PP P+ A G R PA PP P P P G ++ T + ++ + +
Sbjct: 22 PPHAPSSAAFGFPRGAGPAQ-PPAPPAAPEPL------GGICEHETSIDISAYIDPAAFN 74
Query: 689 LNILAFAALYYKRDRRQELRCRRLSPPGGSGSG---VPG-----GGPLLPAAGRELPPEE 740
LA ++ R+QE + P GG G G PG GG ++P PP
Sbjct: 75 DEFLADL---FQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGY 131
Query: 741 ELVSLQLKRGGGVGADP------AEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSG 794
+ G +P A ALRP L +++ P + A L +G
Sbjct: 132 GCAAAGYLDGR---LEPLYERVGAPALRP-------LVIKQEPRE----EDEAKQLALAG 177
Query: 795 LGP-PPPPPPPSLHPFGPFPPPPPTATSH 822
L P PPPPPP HP P PPP A H
Sbjct: 178 LFPYQPPPPPPPSHPH-PHPPPAHLAAPH 205
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 49.7 bits (117), Expect = 1e-05
Identities = 57/214 (26%), Positives = 74/214 (34%), Gaps = 27/214 (12%)
Query: 631 PRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYS--TELSVTVAVGASL-- 686
P PP P PPPP PP P P P + D D + L + G L
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
Query: 687 -LFLNILAFAALYYKRDRRQE----LRCRRLSPPGGSGSGVPGGGPLL-PAAGRELPPEE 740
+N + + + +E R S P G GG P+L PA R++
Sbjct: 62 VTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA--- 118
Query: 741 ELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLL-----APGALTLLPSGL 795
GG G P P+ T++ P P L A GA P
Sbjct: 119 ---------GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRP 169
Query: 796 GPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHP 829
P PPPP P P PPP P+++ L P
Sbjct: 170 NVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSP 203
Score = 38.1 bits (87), Expect = 0.034
Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 27/124 (21%)
Query: 717 GSGSGVPG--------GGPLLPAAGRELPPEEEL--VSLQLKRGGGVGADPAEALRPACP 766
G GS P GPL+P A L E + V A P P P
Sbjct: 125 GPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPP 184
Query: 767 PDYTLALRRAPDDVPLLAP-GALTL---------LPSGLGPPPPPPPPSLHPFGPFPPPP 816
P +P PL++P G LT +P PPPPPPPP+ PPP
Sbjct: 185 PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPT-------PPPL 237
Query: 817 PTAT 820
P A+
Sbjct: 238 PPAS 241
Score = 37.0 bits (84), Expect = 0.076
Identities = 52/215 (24%), Positives = 66/215 (30%), Gaps = 70/215 (32%)
Query: 630 PPRP--PAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLL 687
PPRP PA P T PPPP PP P P
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLPPPLPSSSP------------------------------ 195
Query: 688 FLNILAFAALYYKRDRRQELRCRRLSPPGGSGSG-VPGGGPLLPAAGRELPPEEELVSLQ 746
++ +SPPG G +P P +P A PP
Sbjct: 196 -------------------IKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPP 236
Query: 747 LKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAP---GALTLLPSGLG------- 796
L + +A++P P L L P +PLL P L P+
Sbjct: 237 LPPASVLSD---KAVKPQLAP---LHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPP 290
Query: 797 --PPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHP 829
PPP PP S P P PP + ++ P P
Sbjct: 291 APPPPLPPYASCSPRASLPAPPLPGVNSSSETPPP 325
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.139 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,048,682
Number of Sequences: 37866
Number of extensions: 2856999
Number of successful extensions: 49402
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 518
Number of HSP's successfully gapped in prelim test: 727
Number of HSP's that attempted gapping in prelim test: 24709
Number of HSP's gapped (non-prelim): 16613
length of query: 835
length of database: 18,247,518
effective HSP length: 111
effective length of query: 724
effective length of database: 14,044,392
effective search space: 10168139808
effective search space used: 10168139808
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.