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Search of human proteins with 30795255
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30795255 cell cycle related kinase isoform 1 [Homo sapiens]
(338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30795255 cell cycle related kinase isoform 1 [Homo sapiens] 689 0.0
gi|30795215 cell cycle related kinase isoform 2 [Homo sapiens] 651 0.0
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 639 0.0
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 210 2e-54
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 193 2e-49
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 192 3e-49
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 192 4e-49
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 191 1e-48
gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens] 186 3e-47
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 183 2e-46
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 182 4e-46
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 182 4e-46
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 182 4e-46
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 182 4e-46
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 182 4e-46
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 182 4e-46
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 182 4e-46
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 182 4e-46
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 181 8e-46
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 181 8e-46
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 180 2e-45
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 180 2e-45
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 172 4e-43
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens] 169 2e-42
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 169 2e-42
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 169 2e-42
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 168 6e-42
gi|4502747 cyclin-dependent kinase 9 [Homo sapiens] 164 1e-40
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens] 158 6e-39
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens] 158 6e-39
>gi|30795255 cell cycle related kinase isoform 1 [Homo sapiens]
Length = 338
Score = 689 bits (1778), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY
Sbjct: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 180
LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR
Sbjct: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 180
Query: 181 SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPM 240
SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPM
Sbjct: 181 SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPM 240
Query: 241 PLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGG 300
PLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGG
Sbjct: 241 PLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGG 300
Query: 301 PAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 338
PAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
Sbjct: 301 PAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 338
>gi|30795215 cell cycle related kinase isoform 2 [Homo sapiens]
Length = 325
Score = 651 bits (1679), Expect = 0.0
Identities = 325/338 (96%), Positives = 325/338 (96%), Gaps = 13/338 (3%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
MDQYCILGRIGEGAHGIVFKAKHVE TGEIVALKKVALRRLEDGFPNQ
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVE-------------TGEIVALKKVALRRLEDGFPNQ 47
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY
Sbjct: 48 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 107
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 180
LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR
Sbjct: 108 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 167
Query: 181 SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPM 240
SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPM
Sbjct: 168 SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPM 227
Query: 241 PLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGG 300
PLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGG
Sbjct: 228 PLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGG 287
Query: 301 PAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 338
PAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
Sbjct: 288 PAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 325
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 639 bits (1647), Expect = 0.0
Identities = 325/359 (90%), Positives = 325/359 (90%), Gaps = 34/359 (9%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
MDQYCILGRIGEGAHGIVFKAKHVE TGEIVALKKVALRRLEDGFPNQ
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVE-------------TGEIVALKKVALRRLEDGFPNQ 47
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY
Sbjct: 48 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 107
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 180
LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR
Sbjct: 108 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 167
Query: 181 ---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV
Sbjct: 168 WYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 227
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY 279
WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY
Sbjct: 228 WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY 287
Query: 280 FFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 338
FFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
Sbjct: 288 FFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 346
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 210 bits (534), Expect = 2e-54
Identities = 127/318 (39%), Positives = 185/318 (58%), Gaps = 37/318 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
MD + + +IGEG +G+V+KAK+ E TG++VALKK+ L +G P+
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRE-------------TGQLVALKKIRLDLEMEGVPST 47
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQ-RPLAQAQVKS 119
A+REI L+E++ + +V+L V + L FEF+ DL + + L +KS
Sbjct: 48 AIREISLLKELK-HPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKS 106
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-------------- 165
YL LL+GV+FCH++ ++HRDLKP NLLI+ G +K+ADFGLAR F
Sbjct: 107 YLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTL 166
Query: 166 ---SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
+P+ GS+ YT V S+GCI E++ LFPG ++I+QL + R+LGTP+
Sbjct: 167 WYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDT 226
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY 279
WP +T+LPDY K SF + LEE++P++ P+ DLL Q L Y P QRI A AL H Y
Sbjct: 227 WPGVTQLPDY-KGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPY 285
Query: 280 FFTAPLPAHPSELPIPQR 297
F++P P+ + + QR
Sbjct: 286 -FSSPEPSPAARQYVLQR 302
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 193 bits (490), Expect = 2e-49
Identities = 124/301 (41%), Positives = 165/301 (54%), Gaps = 36/301 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
M +Y L +IGEG +G VFKAK+ E T EIVALK+V L ++G P+
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRE-------------THEIVALKRVRLDDDDEGVPSS 47
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
ALREI L+E++ ++ +V+L V L FEF DL + L VKS+
Sbjct: 48 ALREICLLKELK-HKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSF 106
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFS-------------- 166
L LLKG+ FCH+ N++HRDLKP NLLI+ +G+LK+ADFGLAR F
Sbjct: 107 LFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLW 166
Query: 167 ---PD---GSRLYTHQVATRSVGCIMGELLN-GSPLFPGKNDIEQLCYVLRILGTPNPQV 219
PD G++LY+ + S GCI EL N G PLFPG + +QL + R+LGTP +
Sbjct: 167 YRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQ 226
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY 279
WP +T+LPDY L V+P ++ DLL L P QRI+A +AL H Y
Sbjct: 227 WPSMTKLPDYKPYPM-YPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPY 285
Query: 280 F 280
F
Sbjct: 286 F 286
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 192 bits (489), Expect = 3e-49
Identities = 118/310 (38%), Positives = 172/310 (55%), Gaps = 40/310 (12%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
M+ + + +IGEG +G+V+KA++ TGE+VALKK+ L +G P+
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNK-------------LTGEVVALKKIRLDTETEGVPST 47
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVV-RHAQRPLAQAQVKS 119
A+REI L+E+ ++ +V+L V L FEF+ DL + + A + +KS
Sbjct: 48 AIREISLLKEL-NHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKS 106
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVAT 179
YL LL+G+AFCH++ ++HRDLKP NLLI+ G +K+ADFGLAR F R YTH+V T
Sbjct: 107 YLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVP-VRTYTHEVVT 165
Query: 180 R---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQ 218
S+GCI E++ LFPG ++I+QL + R LGTP+
Sbjct: 166 LWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEV 225
Query: 219 VWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
VWP +T +PDY K SF + +V+P + LL Q L Y P++RI+A AL H
Sbjct: 226 VWPGVTSMPDY-KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284
Query: 279 YF--FTAPLP 286
+F T P+P
Sbjct: 285 FFQDVTKPVP 294
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 192 bits (488), Expect = 4e-49
Identities = 114/303 (37%), Positives = 165/303 (54%), Gaps = 39/303 (12%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
M+ Y + +IGEG +G+V+K +H TG++VA+KK+ L E+G P+
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKT-------------TGQVVAMKKIRLESEEEGVPST 47
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQ--RPLAQAQVK 118
A+REI L+E+ + +V L+ V L FEF+ DL + + + + + VK
Sbjct: 48 AIREISLLKELR-HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVK 106
Query: 119 SYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVA 178
SYL +L+G+ FCH+ ++HRDLKP NLLI G +K+ADFGLAR F R+YTH+V
Sbjct: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-IRVYTHEVV 165
Query: 179 TR---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNP 217
T S+G I EL PLF G ++I+QL + R LGTPN
Sbjct: 166 TLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNN 225
Query: 218 QVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLH 277
+VWPE+ L DY K +F + P L + ++ LDLL + L+Y P +RI+ AL H
Sbjct: 226 EVWPEVESLQDY-KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNH 284
Query: 278 QYF 280
YF
Sbjct: 285 PYF 287
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 191 bits (484), Expect = 1e-48
Identities = 114/302 (37%), Positives = 165/302 (54%), Gaps = 37/302 (12%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
M+ Y + +IGEG +G+V+K +H TG++VA+KK+ L E+G P+
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKT-------------TGQVVAMKKIRLESEEEGVPST 47
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQ--RPLAQAQVK 118
A+REI L+E+ + +V L+ V L FEF+ DL + + + + + VK
Sbjct: 48 AIREISLLKELR-HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVK 106
Query: 119 SYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF------------- 165
SYL +L+G+ FCH+ ++HRDLKP NLLI G +K+ADFGLAR F
Sbjct: 107 SYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAIT 166
Query: 166 ----SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQ 218
SP+ GS Y+ V S+G I EL PLF G ++I+QL + R LGTPN +
Sbjct: 167 LWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNE 226
Query: 219 VWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
VWPE+ L DY K +F + P L + ++ LDLL + L+Y P +RI+ AL H
Sbjct: 227 VWPEVESLQDY-KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHP 285
Query: 279 YF 280
YF
Sbjct: 286 YF 287
>gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens]
Length = 264
Score = 186 bits (471), Expect = 3e-47
Identities = 113/289 (39%), Positives = 165/289 (57%), Gaps = 32/289 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
M+ + + +IGEG +G+V+KA++ TGE+VALKK+ L +G P+
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNK-------------LTGEVVALKKIRLDTETEGVPST 47
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVV-RHAQRPLAQAQVKS 119
A+REI L+E+ ++ +V+L V L FEF+ DL + + A + +KS
Sbjct: 48 AIREISLLKEL-NHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKS 106
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVAT 179
YL LL+G+AFCH++ ++HRDLKP NLLI+ G +K+ADFGLAR F R YTH+V
Sbjct: 107 YLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVP-VRTYTHEVTR 165
Query: 180 RSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVP 239
R+ LFPG ++I+QL + R LGTP+ VWP +T +PDY K SF +
Sbjct: 166 RA-------------LFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY-KPSFPKWAR 211
Query: 240 MPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF--FTAPLP 286
+V+P + LL Q L Y P++RI+A AL H +F T P+P
Sbjct: 212 QDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 260
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 183 bits (465), Expect = 2e-46
Identities = 114/317 (35%), Positives = 164/317 (51%), Gaps = 41/317 (12%)
Query: 3 QYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVAL---RRLEDGFPN 59
+Y L +GEG V+KA+ T +IVA+KK+ L +DG
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKN-------------TNQIVAIKKIKLGHRSEAKDGINR 57
Query: 60 QALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKS 119
ALREIK LQE+ + ++ L F H L F+FM +DL +++ L + +K+
Sbjct: 58 TALREIKLLQELS-HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKA 116
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVAT 179
Y+ M L+G+ + H + I+HRDLKP NLL+ +G LK+ADFGLA+ F +R YTHQV T
Sbjct: 117 YMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFG-SPNRAYTHQVVT 175
Query: 180 R---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQ 218
R +VGCI+ ELL P PG +D++QL + LGTP +
Sbjct: 176 RWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEE 235
Query: 219 VWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
WP++ LPDY ++FK +PL + LDL+ L+ P RI A++AL +
Sbjct: 236 QWPDMCSLPDY--VTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMK 293
Query: 279 YFFTAPLPAHPSELPIP 295
YF P P +LP P
Sbjct: 294 YFSNRPGPTPGCQLPRP 310
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 182 bits (462), Expect = 4e-46
Identities = 113/315 (35%), Positives = 172/315 (54%), Gaps = 35/315 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++++ L RI EG +G+V++AK + T EIVALK++ + + ++GFP
Sbjct: 411 VEEFQCLNRIEEGTYGVVYRAKDKK-------------TDEIVALKRLKMEKEKEGFPIT 457
Query: 61 ALREIKA-LQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKS 119
+LREI L+ N V+ V + + ++ DL ++ ++P +VK+
Sbjct: 458 SLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKT 517
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-------------- 165
+ LL+GV H N I+HRDLK +NLL+S +G LK+ DFGLAR +
Sbjct: 518 LMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTL 577
Query: 166 ---SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
+P+ G++ Y+ V SVGCI GELL PLFPGK++I+Q+ V + LGTP+ ++
Sbjct: 578 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI 637
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
WP +ELP K++F E L + +S Q DL+ +FL Y P +RI+A L H+
Sbjct: 638 WPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHE 697
Query: 279 YFFTAPLPAHPSELP 293
YF PLP PS P
Sbjct: 698 YFRETPLPIDPSMFP 712
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 182 bits (462), Expect = 4e-46
Identities = 113/315 (35%), Positives = 172/315 (54%), Gaps = 35/315 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++++ L RI EG +G+V++AK + T EIVALK++ + + ++GFP
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKK-------------TDEIVALKRLKMEKEKEGFPIT 466
Query: 61 ALREIKA-LQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKS 119
+LREI L+ N V+ V + + ++ DL ++ ++P +VK+
Sbjct: 467 SLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKT 526
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-------------- 165
+ LL+GV H N I+HRDLK +NLL+S +G LK+ DFGLAR +
Sbjct: 527 LMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTL 586
Query: 166 ---SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
+P+ G++ Y+ V SVGCI GELL PLFPGK++I+Q+ V + LGTP+ ++
Sbjct: 587 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI 646
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
WP +ELP K++F E L + +S Q DL+ +FL Y P +RI+A L H+
Sbjct: 647 WPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHE 706
Query: 279 YFFTAPLPAHPSELP 293
YF PLP PS P
Sbjct: 707 YFRETPLPIDPSMFP 721
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 182 bits (462), Expect = 4e-46
Identities = 113/315 (35%), Positives = 172/315 (54%), Gaps = 35/315 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++++ L RI EG +G+V++AK + T EIVALK++ + + ++GFP
Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKK-------------TDEIVALKRLKMEKEKEGFPIT 434
Query: 61 ALREIKA-LQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKS 119
+LREI L+ N V+ V + + ++ DL ++ ++P +VK+
Sbjct: 435 SLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKT 494
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-------------- 165
+ LL+GV H N I+HRDLK +NLL+S +G LK+ DFGLAR +
Sbjct: 495 LMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTL 554
Query: 166 ---SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
+P+ G++ Y+ V SVGCI GELL PLFPGK++I+Q+ V + LGTP+ ++
Sbjct: 555 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI 614
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
WP +ELP K++F E L + +S Q DL+ +FL Y P +RI+A L H+
Sbjct: 615 WPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHE 674
Query: 279 YFFTAPLPAHPSELP 293
YF PLP PS P
Sbjct: 675 YFRETPLPIDPSMFP 689
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 182 bits (462), Expect = 4e-46
Identities = 113/315 (35%), Positives = 172/315 (54%), Gaps = 35/315 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++++ L RI EG +G+V++AK + T EIVALK++ + + ++GFP
Sbjct: 377 VEEFQCLNRIEEGTYGVVYRAKDKK-------------TDEIVALKRLKMEKEKEGFPIT 423
Query: 61 ALREIKA-LQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKS 119
+LREI L+ N V+ V + + ++ DL ++ ++P +VK+
Sbjct: 424 SLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKT 483
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-------------- 165
+ LL+GV H N I+HRDLK +NLL+S +G LK+ DFGLAR +
Sbjct: 484 LMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTL 543
Query: 166 ---SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
+P+ G++ Y+ V SVGCI GELL PLFPGK++I+Q+ V + LGTP+ ++
Sbjct: 544 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI 603
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
WP +ELP K++F E L + +S Q DL+ +FL Y P +RI+A L H+
Sbjct: 604 WPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHE 663
Query: 279 YFFTAPLPAHPSELP 293
YF PLP PS P
Sbjct: 664 YFRETPLPIDPSMFP 678
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 182 bits (462), Expect = 4e-46
Identities = 113/315 (35%), Positives = 172/315 (54%), Gaps = 35/315 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++++ L RI EG +G+V++AK + T EIVALK++ + + ++GFP
Sbjct: 166 VEEFQCLNRIEEGTYGVVYRAKDKK-------------TDEIVALKRLKMEKEKEGFPIT 212
Query: 61 ALREIKA-LQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKS 119
+LREI L+ N V+ V + + ++ DL ++ ++P +VK+
Sbjct: 213 SLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKT 272
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-------------- 165
+ LL+GV H N I+HRDLK +NLL+S +G LK+ DFGLAR +
Sbjct: 273 LMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTL 332
Query: 166 ---SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
+P+ G++ Y+ V SVGCI GELL PLFPGK++I+Q+ V + LGTP+ ++
Sbjct: 333 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI 392
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
WP +ELP K++F E L + +S Q DL+ +FL Y P +RI+A L H+
Sbjct: 393 WPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHE 452
Query: 279 YFFTAPLPAHPSELP 293
YF PLP PS P
Sbjct: 453 YFRETPLPIDPSMFP 467
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 182 bits (462), Expect = 4e-46
Identities = 113/315 (35%), Positives = 172/315 (54%), Gaps = 35/315 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++++ L RI EG +G+V++AK + T EIVALK++ + + ++GFP
Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKK-------------TDEIVALKRLKMEKEKEGFPIT 468
Query: 61 ALREIKA-LQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKS 119
+LREI L+ N V+ V + + ++ DL ++ ++P +VK+
Sbjct: 469 SLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKT 528
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-------------- 165
+ LL+GV H N I+HRDLK +NLL+S +G LK+ DFGLAR +
Sbjct: 529 LMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTL 588
Query: 166 ---SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
+P+ G++ Y+ V SVGCI GELL PLFPGK++I+Q+ V + LGTP+ ++
Sbjct: 589 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI 648
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
WP +ELP K++F E L + +S Q DL+ +FL Y P +RI+A L H+
Sbjct: 649 WPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHE 708
Query: 279 YFFTAPLPAHPSELP 293
YF PLP PS P
Sbjct: 709 YFRETPLPIDPSMFP 723
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 182 bits (462), Expect = 4e-46
Identities = 110/326 (33%), Positives = 174/326 (53%), Gaps = 49/326 (15%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
+D++ I+G IGEG +G V+KA+ + TGE+VALKKV L ++GFP
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKD-------------TGEMVALKKVRLDNEKEGFPIT 748
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHG----------GGFVLAFEFMLSDLAEVVRHAQR 110
A+REIK L+++ +Q ++ +K + G F L FE+M DL ++
Sbjct: 749 AIREIKILRQLT-HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLV 807
Query: 111 PLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGS 170
+ +KS+++ L++G+ +CH N +HRD+K +N+L++ GQ+K+ADFGLAR++S + S
Sbjct: 808 HFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEES 867
Query: 171 RLYTHQVATR---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVL 209
R YT++V T S GCI+GEL P+F ++ QL +
Sbjct: 868 RPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIS 927
Query: 210 RILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRI 269
RI G+P P VWP++ +LP +N + K+Q L E + ALDL L P +R
Sbjct: 928 RICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRC 987
Query: 270 AASKALLHQYFFTAPLPAHPSELPIP 295
A +AL ++ PS++P P
Sbjct: 988 TAEQALQCEFL----RDVEPSKMPPP 1009
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 182 bits (462), Expect = 4e-46
Identities = 110/326 (33%), Positives = 174/326 (53%), Gaps = 49/326 (15%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
+D++ I+G IGEG +G V+KA+ + TGE+VALKKV L ++GFP
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKD-------------TGEMVALKKVRLDNEKEGFPIT 748
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHG----------GGFVLAFEFMLSDLAEVVRHAQR 110
A+REIK L+++ +Q ++ +K + G F L FE+M DL ++
Sbjct: 749 AIREIKILRQLT-HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLV 807
Query: 111 PLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGS 170
+ +KS+++ L++G+ +CH N +HRD+K +N+L++ GQ+K+ADFGLAR++S + S
Sbjct: 808 HFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEES 867
Query: 171 RLYTHQVATR---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVL 209
R YT++V T S GCI+GEL P+F ++ QL +
Sbjct: 868 RPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIS 927
Query: 210 RILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRI 269
RI G+P P VWP++ +LP +N + K+Q L E + ALDL L P +R
Sbjct: 928 RICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRC 987
Query: 270 AASKALLHQYFFTAPLPAHPSELPIP 295
A +AL ++ PS++P P
Sbjct: 988 TAEQALQCEFL----RDVEPSKMPPP 1009
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 181 bits (459), Expect = 8e-46
Identities = 111/325 (34%), Positives = 174/325 (53%), Gaps = 46/325 (14%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
+D++ I+G IGEG +G V+KAK + TGE+VALKKV L ++GFP
Sbjct: 724 VDKFDIIGIIGEGTYGQVYKAKDKD-------------TGELVALKKVRLDNEKEGFPIT 770
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHG----------GGFVLAFEFMLSDLAEVVRHAQR 110
A+REIK L+++ ++ VV +K + G F L FE+M DL ++
Sbjct: 771 AIREIKILRQLI-HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLV 829
Query: 111 PLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGS 170
++ +KS+++ L++G+ +CH N +HRD+K +N+L++ SGQ+K+ADFGLAR+++ + S
Sbjct: 830 HFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEES 889
Query: 171 RLYTHQVATR---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVL 209
R YT++V T S GCI+GEL P+F ++ QL +
Sbjct: 890 RPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELIS 949
Query: 210 RILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRI 269
R+ G+P P VWP++ +LP +N + K+Q L E + ALDLL L P +R
Sbjct: 950 RLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRC 1009
Query: 270 AASKALLHQYFFTAPL-PAHPSELP 293
A + L + L P +LP
Sbjct: 1010 TAEQTLQSDFLKDVELSKMAPPDLP 1034
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 181 bits (459), Expect = 8e-46
Identities = 111/325 (34%), Positives = 174/325 (53%), Gaps = 46/325 (14%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
+D++ I+G IGEG +G V+KAK + TGE+VALKKV L ++GFP
Sbjct: 724 VDKFDIIGIIGEGTYGQVYKAKDKD-------------TGELVALKKVRLDNEKEGFPIT 770
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHG----------GGFVLAFEFMLSDLAEVVRHAQR 110
A+REIK L+++ ++ VV +K + G F L FE+M DL ++
Sbjct: 771 AIREIKILRQLI-HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLV 829
Query: 111 PLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGS 170
++ +KS+++ L++G+ +CH N +HRD+K +N+L++ SGQ+K+ADFGLAR+++ + S
Sbjct: 830 HFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEES 889
Query: 171 RLYTHQVATR---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVL 209
R YT++V T S GCI+GEL P+F ++ QL +
Sbjct: 890 RPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELIS 949
Query: 210 RILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRI 269
R+ G+P P VWP++ +LP +N + K+Q L E + ALDLL L P +R
Sbjct: 950 RLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRC 1009
Query: 270 AASKALLHQYFFTAPL-PAHPSELP 293
A + L + L P +LP
Sbjct: 1010 TAEQTLQSDFLKDVELSKMAPPDLP 1034
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 180 bits (456), Expect = 2e-45
Identities = 112/315 (35%), Positives = 171/315 (54%), Gaps = 35/315 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++++ L RI EG +G+V++AK + T EIVALK++ + + ++GFP
Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKK-------------TDEIVALKRLKMEKEKEGFPIT 456
Query: 61 ALREIKA-LQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKS 119
+LREI L+ N V+ V + + ++ DL ++ ++P +VK+
Sbjct: 457 SLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKT 516
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-------------- 165
+ LL+GV H N I+HRDLK +NLL+S +G LK+ DFGLAR +
Sbjct: 517 LMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQ 576
Query: 166 ---SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
+P+ G++ Y+ V SVGCI GELL PLFPG ++I+Q+ V + LGTP+ ++
Sbjct: 577 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 636
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
WP +ELP K++F E L + +S Q DL+ +FL Y P +RI+A L H+
Sbjct: 637 WPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHE 696
Query: 279 YFFTAPLPAHPSELP 293
YF PLP PS P
Sbjct: 697 YFRETPLPIDPSMFP 711
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 180 bits (456), Expect = 2e-45
Identities = 112/315 (35%), Positives = 171/315 (54%), Gaps = 35/315 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++++ L RI EG +G+V++AK + T EIVALK++ + + ++GFP
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKK-------------TDEIVALKRLKMEKEKEGFPIT 466
Query: 61 ALREIKA-LQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKS 119
+LREI L+ N V+ V + + ++ DL ++ ++P +VK+
Sbjct: 467 SLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKT 526
Query: 120 YLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-------------- 165
+ LL+GV H N I+HRDLK +NLL+S +G LK+ DFGLAR +
Sbjct: 527 LMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQ 586
Query: 166 ---SPD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV 219
+P+ G++ Y+ V SVGCI GELL PLFPG ++I+Q+ V + LGTP+ ++
Sbjct: 587 WYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI 646
Query: 220 WPELTELPDYNKISFKEQVPMPLEEVLPD-VSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
WP +ELP K++F E L + +S Q DL+ +FL Y P +RI+A L H+
Sbjct: 647 WPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHE 706
Query: 279 YFFTAPLPAHPSELP 293
YF PLP PS P
Sbjct: 707 YFRETPLPIDPSMFP 721
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 172 bits (436), Expect = 4e-43
Identities = 108/309 (34%), Positives = 162/309 (52%), Gaps = 36/309 (11%)
Query: 7 LGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQALREIK 66
L RIGEG +GIV++A+ QT EIVALKKV + + +DG P +LREI
Sbjct: 42 LNRIGEGTYGIVYRARDT-------------QTDEIVALKKVRMDKEKDGIPISSLREIT 88
Query: 67 ALQEMEDNQYVVQLKAVFP--HGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQML 124
L + + +V+LK V H L + DLA ++ + P ++AQVK + +
Sbjct: 89 LLLRLR-HPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQV 147
Query: 125 LKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVF-----------------SP 167
L+G+ + H N I+HRDLK +NLL++ G +K ADFGLAR + +P
Sbjct: 148 LRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAP 207
Query: 168 D---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELT 224
+ G+ T + +VGCI+ ELL PL PG ++I Q+ ++++LGTP+ +WP +
Sbjct: 208 ELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFS 267
Query: 225 ELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAP 284
+LP + S ++Q L+ P +S L LL +Y P +R A L YF P
Sbjct: 268 KLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKP 327
Query: 285 LPAHPSELP 293
LP P +P
Sbjct: 328 LPCEPELMP 336
>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
Length = 504
Score = 169 bits (429), Expect = 2e-42
Identities = 104/300 (34%), Positives = 152/300 (50%), Gaps = 35/300 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++ Y L ++GEG + VFK + T +VALK++ L E+G P
Sbjct: 171 LETYVKLDKLGEGTYATVFKGRSK-------------LTENLVALKEIRLEH-EEGAPCT 216
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
A+RE+ L+ ++ + +V L + L FE++ SDL + + H ++ VK +
Sbjct: 217 AIREVSLLKNLK-HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIF 275
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFS-------------- 166
+ LL+G+A+CH I+HRDLKP NLLI+ G+LK+ADFGLAR S
Sbjct: 276 MFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLW 335
Query: 167 ---PD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVW 220
PD GS Y+ + VGCI E+ G PLFPG E+L + R+LGTP + W
Sbjct: 336 YRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETW 395
Query: 221 PELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 280
P +T ++ SF +P PL P + + LL LLY R++A AL H YF
Sbjct: 396 PGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 455
>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 169 bits (429), Expect = 2e-42
Identities = 104/300 (34%), Positives = 152/300 (50%), Gaps = 35/300 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++ Y L ++GEG + VFK + T +VALK++ L E+G P
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSK-------------LTENLVALKEIRLEH-EEGAPCT 186
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
A+RE+ L+ ++ + +V L + L FE++ SDL + + H ++ VK +
Sbjct: 187 AIREVSLLKNLK-HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIF 245
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFS-------------- 166
+ LL+G+A+CH I+HRDLKP NLLI+ G+LK+ADFGLAR S
Sbjct: 246 MFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLW 305
Query: 167 ---PD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVW 220
PD GS Y+ + VGCI E+ G PLFPG E+L + R+LGTP + W
Sbjct: 306 YRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETW 365
Query: 221 PELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 280
P +T ++ SF +P PL P + + LL LLY R++A AL H YF
Sbjct: 366 PGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 425
>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 169 bits (429), Expect = 2e-42
Identities = 104/300 (34%), Positives = 152/300 (50%), Gaps = 35/300 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
++ Y L ++GEG + VFK + T +VALK++ L E+G P
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSK-------------LTENLVALKEIRLEH-EEGAPCT 186
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
A+RE+ L+ ++ + +V L + L FE++ SDL + + H ++ VK +
Sbjct: 187 AIREVSLLKNLK-HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIF 245
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFS-------------- 166
+ LL+G+A+CH I+HRDLKP NLLI+ G+LK+ADFGLAR S
Sbjct: 246 MFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLW 305
Query: 167 ---PD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVW 220
PD GS Y+ + VGCI E+ G PLFPG E+L + R+LGTP + W
Sbjct: 306 YRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETW 365
Query: 221 PELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 280
P +T ++ SF +P PL P + + LL LLY R++A AL H YF
Sbjct: 366 PGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 425
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 168 bits (426), Expect = 6e-42
Identities = 97/300 (32%), Positives = 159/300 (53%), Gaps = 35/300 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
M+ Y L ++GEG + V+K + T +VALK++ L E+G P
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSK-------------LTENLVALKEIRLEH-EEGAPCT 234
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
A+RE+ L++++ + +V L + L FE++ DL + + ++ VK +
Sbjct: 235 AIREVSLLKDLK-HANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLF 293
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFS-------------- 166
L +L+G+A+CH ++HRDLKP NLLI+ G+LK+ADFGLAR S
Sbjct: 294 LYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLW 353
Query: 167 ---PD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVW 220
PD GS Y+ Q+ VGCI E+ +G PLFPG ++L + R+LGTP+ + W
Sbjct: 354 YRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETW 413
Query: 221 PELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 280
P ++ ++ +F + P PL P + + ++L+ +FL Y +R++A +A+ H YF
Sbjct: 414 PGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF 473
>gi|4502747 cyclin-dependent kinase 9 [Homo sapiens]
Length = 372
Score = 164 bits (414), Expect = 1e-40
Identities = 109/322 (33%), Positives = 163/322 (50%), Gaps = 50/322 (15%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
+ +Y L +IG+G G VFKA+H +TG+ VALKKV + ++GFP
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARH-------------RKTGQKVALKKVLMENEKEGFPIT 62
Query: 61 ALREIKALQEMEDNQYVVQLKA----VFPHG---GGFVLAFEFMLSDLAEVVRHAQRPLA 113
ALREIK LQ ++ V ++ P+ G L F+F DLA ++ +
Sbjct: 63 ALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFT 122
Query: 114 QAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFS------- 166
+++K +QMLL G+ + H N I+HRD+K AN+LI+ G LK+ADFGLAR FS
Sbjct: 123 LSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQP 182
Query: 167 --------------PD---GSRLYTHQVATRSVGCIMGELLNGSPLFPGKNDIEQLCYVL 209
P+ G R Y + GCIM E+ SP+ G + QL +
Sbjct: 183 NRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALIS 242
Query: 210 RILGTPNPQVWPELTELPDYNKISF----KEQVPMPLEEVLPDVSPQALDLLGQFLLYPP 265
++ G+ P+VWP + Y K+ K +V L+ + D P ALDL+ + L+ P
Sbjct: 243 QLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRD--PYALDLIDKLLVLDP 300
Query: 266 HQRIAASKALLHQYFFTAPLPA 287
QRI + AL H +F++ P+P+
Sbjct: 301 AQRIDSDDALNHDFFWSDPMPS 322
>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
Length = 1030
Score = 158 bits (400), Expect = 6e-39
Identities = 105/307 (34%), Positives = 154/307 (50%), Gaps = 36/307 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
M+++ ILG +GEGA+G+V K +H E T EIVA+KK +
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKE-------------THEIVAIKKFKDSEENEEVKET 56
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
LRE+K L+ ++ +V+LK F G L FE++ ++ E++ + +VKSY
Sbjct: 57 TLRELKMLRTLKQEN-IVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSY 115
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 180
+ L+K + +CH N+IVHRD+KP NLLIS + LK+ DFG AR S + YT VATR
Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATR 175
Query: 181 --------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVW 220
SVGCI+GEL +G PLFPG+++I+QL + ++LG +
Sbjct: 176 WYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQM 235
Query: 221 PELTELPDYNKISFKE-QVPMPLE-EVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
P ++ + F P LE L ++ LDL+ L P R + L H
Sbjct: 236 KLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHP 295
Query: 279 YFFTAPL 285
F T L
Sbjct: 296 TFQTQRL 302
>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
Length = 1030
Score = 158 bits (400), Expect = 6e-39
Identities = 105/307 (34%), Positives = 154/307 (50%), Gaps = 36/307 (11%)
Query: 1 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ 60
M+++ ILG +GEGA+G+V K +H E T EIVA+KK +
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKE-------------THEIVAIKKFKDSEENEEVKET 56
Query: 61 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY 120
LRE+K L+ ++ +V+LK F G L FE++ ++ E++ + +VKSY
Sbjct: 57 TLRELKMLRTLKQEN-IVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSY 115
Query: 121 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR 180
+ L+K + +CH N+IVHRD+KP NLLIS + LK+ DFG AR S + YT VATR
Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATR 175
Query: 181 --------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVW 220
SVGCI+GEL +G PLFPG+++I+QL + ++LG +
Sbjct: 176 WYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQM 235
Query: 221 PELTELPDYNKISFKE-QVPMPLE-EVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQ 278
P ++ + F P LE L ++ LDL+ L P R + L H
Sbjct: 236 KLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHP 295
Query: 279 YFFTAPL 285
F T L
Sbjct: 296 TFQTQRL 302
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.141 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,665,559
Number of Sequences: 37866
Number of extensions: 787231
Number of successful extensions: 4622
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 734
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 3075
Number of HSP's gapped (non-prelim): 1057
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.