Guide to the Human Genome
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Search of human proteins with 30425534

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30425534 tetraspanin 33 [Homo sapiens]
         (283 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30425534 tetraspanin 33 [Homo sapiens]                             576   e-165
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom...   234   6e-62
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom...   230   9e-61
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]       229   2e-60
gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom...   225   4e-59
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                  222   3e-58
gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]       196   1e-50
gi|119120834 tetraspanin 10 [Homo sapiens]                            155   4e-38
gi|4502679 CD63 antigen isoform A [Homo sapiens]                      131   6e-31
gi|91199546 CD63 antigen isoform B [Homo sapiens]                     126   2e-29
gi|21265104 tetraspanin 7 [Homo sapiens]                              108   4e-24
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                    108   4e-24
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                     108   4e-24
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                    108   4e-24
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                    108   4e-24
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                    108   4e-24
gi|68799997 tetraspanin 4 isoform a [Homo sapiens]                    108   4e-24
gi|5729941 tetraspanin 9 [Homo sapiens]                               108   5e-24
gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]                  107   1e-23
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]        107   2e-23
gi|87159824 CD151 antigen [Homo sapiens]                              105   3e-23
gi|87159822 CD151 antigen [Homo sapiens]                              105   3e-23
gi|21237751 CD151 antigen [Homo sapiens]                              105   3e-23
gi|21237748 CD151 antigen [Homo sapiens]                              105   3e-23
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                      104   8e-23
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]        101   6e-22
gi|122937466 tetraspanin 11 [Homo sapiens]                            100   1e-21
gi|10834972 CD53 antigen [Homo sapiens]                                94   1e-19
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ...    94   1e-19
gi|91106727 CD53 antigen [Homo sapiens]                                94   1e-19

>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score =  576 bits (1484), Expect = e-165
 Identities = 283/283 (100%), Positives = 283/283 (100%)

Query: 1   MARRPRAPAASGEEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL 60
           MARRPRAPAASGEEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL
Sbjct: 1   MARRPRAPAASGEEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL 60

Query: 61  AVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSD 120
           AVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSD
Sbjct: 61  AVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSD 120

Query: 121 KARGKVSEIINNAIVHYRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSR 180
           KARGKVSEIINNAIVHYRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSR
Sbjct: 121 KARGKVSEIINNAIVHYRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSR 180

Query: 181 ERCSVPYSCCLPTPDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLG 240
           ERCSVPYSCCLPTPDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLG
Sbjct: 181 ERCSVPYSCCLPTPDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLG 240

Query: 241 GVALGLAIPQLVGILLSQILVNQIKDQIKLQLYNQQHRADPWY 283
           GVALGLAIPQLVGILLSQILVNQIKDQIKLQLYNQQHRADPWY
Sbjct: 241 GVALGLAIPQLVGILLSQILVNQIKDQIKLQLYNQQHRADPWY 283


>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
           sapiens]
          Length = 329

 Score =  234 bits (597), Expect = 6e-62
 Identities = 115/247 (46%), Positives = 164/247 (66%), Gaps = 4/247 (1%)

Query: 23  KYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA----VDPAILLIVVGVLMFLL 78
           KY LF FN++FWV+  + +A+G++A   K   + ++ L     +DP  L +VVG +M +L
Sbjct: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77

Query: 79  TFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYR 138
            F GCIG+LREN  LL+ FS+ L  +F L+LA GIL FVF D  R +++  INN +  YR
Sbjct: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137

Query: 139 DDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAV 198
           DD+DLQNLIDF Q+ +SCCG     DW+ N+YFNC++ NPSRERC VP+SCC+  P + V
Sbjct: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197

Query: 199 INTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQ 258
           +NT CG  ++    LE    I+T GC+ +   W+  NL ++ GV +G+A+ Q+ GI L+Q
Sbjct: 198 LNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGICLAQ 257

Query: 259 ILVNQIK 265
            LV+ IK
Sbjct: 258 NLVSDIK 264


>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
           sapiens]
          Length = 332

 Score =  230 bits (587), Expect = 9e-61
 Identities = 115/250 (46%), Positives = 164/250 (65%), Gaps = 7/250 (2%)

Query: 23  KYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA----VDPAILLIVVGVLMFLL 78
           KY LF FN++FWV+  + +A+G++A   K   + ++ L     +DP  L +VVG +M +L
Sbjct: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77

Query: 79  TFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYR 138
            F GCIG+LREN  LL+ FS+ L  +F L+LA GIL FVF D  R +++  INN +  YR
Sbjct: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137

Query: 139 DDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAV 198
           DD+DLQNLIDF Q+ +SCCG     DW+ N+YFNC++ NPSRERC VP+SCC+  P + V
Sbjct: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197

Query: 199 INTMCGQGMQ---AFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGIL 255
           +NT CG  ++       LE    I+T GC+ +   W+  NL ++ GV +G+A+ Q+ GI 
Sbjct: 198 LNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGIC 257

Query: 256 LSQILVNQIK 265
           L+Q LV+ IK
Sbjct: 258 LAQNLVSDIK 267


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score =  229 bits (584), Expect = 2e-60
 Identities = 110/252 (43%), Positives = 161/252 (63%), Gaps = 4/252 (1%)

Query: 18  VSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA----VDPAILLIVVGV 73
           VS  +KY +F FN++FW + +  + +G++A   K   + ++ +      DP  L +VVG 
Sbjct: 11  VSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGG 70

Query: 74  LMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNA 133
           +MF+L F GCIG+LREN  LL+ FS+ L  +F L+L AG+L FVF D  + ++   INN 
Sbjct: 71  VMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNN 130

Query: 134 IVHYRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPT 193
           I  YRDD+DLQNLIDF Q+ + CCG     DW+ N+YFNC++ N SRERC VP+SCC   
Sbjct: 131 IRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKD 190

Query: 194 PDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVG 253
           P + VINT CG   +    ++   VIYT GC+ +   W+  NL ++ G+ +G+A+ Q+ G
Sbjct: 191 PAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFG 250

Query: 254 ILLSQILVNQIK 265
           I L+Q LV+ I+
Sbjct: 251 ICLAQNLVSDIE 262


>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
           sapiens]
          Length = 266

 Score =  225 bits (573), Expect = 4e-59
 Identities = 112/245 (45%), Positives = 160/245 (65%), Gaps = 7/245 (2%)

Query: 23  KYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA----VDPAILLIVVGVLMFLL 78
           KY LF FN++FWV+  + +A+G++A   K   + ++ L     +DP  L +VVG +M +L
Sbjct: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77

Query: 79  TFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYR 138
            F GCIG+LREN  LL+ FS+ L  +F L+LA GIL FVF D  R +++  INN +  YR
Sbjct: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137

Query: 139 DDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAV 198
           DD+DLQNLIDF Q+ +SCCG     DW+ N+YFNC++ NPSRERC VP+SCC+  P + V
Sbjct: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197

Query: 199 INTMCGQGMQ---AFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGIL 255
           +NT CG  ++       LE    I+T GC+ +   W+  NL ++ GV +G+A+ Q+ GI 
Sbjct: 198 LNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGIC 257

Query: 256 LSQIL 260
           L+Q L
Sbjct: 258 LAQNL 262


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score =  222 bits (565), Expect = 3e-58
 Identities = 106/252 (42%), Positives = 160/252 (63%), Gaps = 4/252 (1%)

Query: 18  VSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA----VDPAILLIVVGV 73
           VS   KYLLF +N++FW+  +V + VG++A   K   + L  +     +DP +L+++VGV
Sbjct: 11  VSCWYKYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGV 70

Query: 74  LMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNA 133
           +MF L F GC+G+LRENICLL  F   +  +F L+LA  +L F+F D  R +  E   + 
Sbjct: 71  VMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESN 130

Query: 134 IVHYRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPT 193
           I  YRDD+DLQNLID  QK   CCG    +DW  N+YFNCS  + SRE+C VP+SCC+P 
Sbjct: 131 IKSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPD 190

Query: 194 PDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVG 253
           P Q V+NT CG  ++     +  + I+T GCI  L +W+  N++++ GV + +++ Q+ G
Sbjct: 191 PAQKVVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFG 250

Query: 254 ILLSQILVNQIK 265
           I L++ L++ I+
Sbjct: 251 IFLARTLISDIE 262


>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
          Length = 294

 Score =  196 bits (499), Expect = 1e-50
 Identities = 89/247 (36%), Positives = 151/247 (61%), Gaps = 3/247 (1%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFC 81
           +K+ L  ++ +FW+I  ++++VG+YA + +     L    + PAI+LI++GV+MF+++F 
Sbjct: 20  LKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFLAPAIILILLGVVMFMVSFI 79

Query: 82  GCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDL 141
           G + SLR+N+ LLQ F   L    +++L  G++   F ++    +++ I   I +Y DDL
Sbjct: 80  GVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDDL 139

Query: 142 DLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVINT 201
           D +N++DF QKKF CCGG  Y+DWS+N Y +CS   P    C VPY+CC+    + V+NT
Sbjct: 140 DFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPL--ACGVPYTCCIRNTTE-VVNT 196

Query: 202 MCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILV 261
           MCG      +      VIY  GC + ++ W   N  ++ G+ LG+ +PQ +G+LL+ + +
Sbjct: 197 MCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYI 256

Query: 262 NQIKDQI 268
            +++D I
Sbjct: 257 TRVEDII 263


>gi|119120834 tetraspanin 10 [Homo sapiens]
          Length = 355

 Score =  155 bits (392), Expect = 4e-38
 Identities = 87/249 (34%), Positives = 137/249 (55%), Gaps = 5/249 (2%)

Query: 19  SPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAAL--ACLAVDPAILLIVVGVLMF 76
           S  VKYL+F  N  F ++ ++ +A+G++   +K +  +     L  DP + L + G+++ 
Sbjct: 73  SSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVVS 132

Query: 77  LLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH 136
            ++  G +G+L EN CLL+ FS  + A  +L+  AG L        +  +   +  AI H
Sbjct: 133 AVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAH 192

Query: 137 YRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCL-PTPD 195
           Y+DD DL+ L+D  Q    CCG  SY+DW QN+YFNCS  +P  + CS+P SCC+ P  D
Sbjct: 193 YQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCS--SPGVQACSLPASCCIDPRED 250

Query: 196 QAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGIL 255
            A +N  CG G+   D   A +V+Y  GC   L  W+ +NL   GG A+ + + Q   +L
Sbjct: 251 GASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELL 310

Query: 256 LSQILVNQI 264
           L+  L+  +
Sbjct: 311 LAARLLGAL 319


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score =  131 bits (330), Expect = 6e-31
 Identities = 75/245 (30%), Positives = 127/245 (51%), Gaps = 23/245 (9%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPA-ILLIVVGVLMFLLTF 80
           VK+LL+   + F   ++ ++AVGV A+L+                +++I VGV +FL+ F
Sbjct: 10  VKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAF 69

Query: 81  CGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDD 140
            GC G+ +EN CL+ TF++ L+ + L+++AA I G+VF DK   + +      + +Y  +
Sbjct: 70  VGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKN 129

Query: 141 LDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVIN 200
               +++D  Q  F CCG  +Y DW         E  PS  +  VP SCC        IN
Sbjct: 130 NHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCC--------IN 172

Query: 201 TMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQIL 260
              G G+   +     K I+  GC++K+  W+  N+ ++   ALG+A  +++GI+ +  L
Sbjct: 173 VTVGCGINFNE-----KAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCL 227

Query: 261 VNQIK 265
           V  I+
Sbjct: 228 VKSIR 232


>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score =  126 bits (317), Expect = 2e-29
 Identities = 75/245 (30%), Positives = 126/245 (51%), Gaps = 25/245 (10%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPA-ILLIVVGVLMFLLTF 80
           VK+LL+   + F   ++ ++AVGV A+L+                +++I VGV +FL+ F
Sbjct: 10  VKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAF 69

Query: 81  CGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDD 140
            GC G+ +EN CL+ TF++ L+ + L+++AA I G+VF DK   + +      + +Y  +
Sbjct: 70  VGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKN 129

Query: 141 LDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVIN 200
               +++D  Q  F CCG  +Y DW         E  PS  +  VP SCC        IN
Sbjct: 130 NHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCC--------IN 172

Query: 201 TMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQIL 260
              G G+   +     K I+  GC++K+  W+  N+ ++   ALG+A   ++GI+ +  L
Sbjct: 173 VTVGCGINFNE-----KAIHKEGCVEKIGGWLRKNVLVVAAAALGIAF--VLGIVFACCL 225

Query: 261 VNQIK 265
           V  I+
Sbjct: 226 VKSIR 230


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score =  108 bits (271), Expect = 4e-24
 Identities = 65/237 (27%), Positives = 119/237 (50%), Gaps = 18/237 (7%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAAL-ACLAVDPAILLIVVGVLMFLLTF 80
           +K LL  ++ +FW+  ++++AVGV+ +L      +L A  + +   +LI  G  + +   
Sbjct: 15  LKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGL 74

Query: 81  CGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDD 140
            GC  + R +  +L+ +++ L+ VFL +L AGI GFVF  + +        +A+  Y  +
Sbjct: 75  FGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNGN 134

Query: 141 LDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVIN 200
            +    +D  Q+  SCCG  +Y +WS + YF             +P SCC+   D     
Sbjct: 135 DERSRAVDHVQRSLSCCGVQNYTNWSTSPYF---------LEHGIPPSCCMNETD----- 180

Query: 201 TMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLS 257
             C       +   A+  +   GC D + +++ +N+ ++ GVA G+A  QL+G+LL+
Sbjct: 181 --CNP-QDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLA 234


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  108 bits (271), Expect = 4e-24
 Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 29/247 (11%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL--AVDPAILLIVVGVLMFLLT 79
           VKYL+F FN+LFW+    ++ VG++    + + A L+    ++  A LLI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHY-- 137
           F GC+G+++EN CLL TF L L  VFLL+    IL F ++DK      + +   +  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 138 RDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQA 197
           + ++ L N     Q  F CCG  +Y DW +   +N +          VP SCCL      
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE--VYNATR---------VPDSCCLE----- 172

Query: 198 VINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLS 257
             +  CG        L A    +   C + +  W+  NL  +G   L  A+ Q++G+  +
Sbjct: 173 -FSESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223

Query: 258 QILVNQI 264
             +  Q+
Sbjct: 224 MTMYCQV 230


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  108 bits (271), Expect = 4e-24
 Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 29/247 (11%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL--AVDPAILLIVVGVLMFLLT 79
           VKYL+F FN+LFW+    ++ VG++    + + A L+    ++  A LLI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHY-- 137
           F GC+G+++EN CLL TF L L  VFLL+    IL F ++DK      + +   +  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 138 RDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQA 197
           + ++ L N     Q  F CCG  +Y DW +   +N +          VP SCCL      
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE--VYNATR---------VPDSCCLE----- 172

Query: 198 VINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLS 257
             +  CG        L A    +   C + +  W+  NL  +G   L  A+ Q++G+  +
Sbjct: 173 -FSESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223

Query: 258 QILVNQI 264
             +  Q+
Sbjct: 224 MTMYCQV 230


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  108 bits (271), Expect = 4e-24
 Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 29/247 (11%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL--AVDPAILLIVVGVLMFLLT 79
           VKYL+F FN+LFW+    ++ VG++    + + A L+    ++  A LLI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHY-- 137
           F GC+G+++EN CLL TF L L  VFLL+    IL F ++DK      + +   +  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 138 RDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQA 197
           + ++ L N     Q  F CCG  +Y DW +   +N +          VP SCCL      
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE--VYNATR---------VPDSCCLE----- 172

Query: 198 VINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLS 257
             +  CG        L A    +   C + +  W+  NL  +G   L  A+ Q++G+  +
Sbjct: 173 -FSESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223

Query: 258 QILVNQI 264
             +  Q+
Sbjct: 224 MTMYCQV 230


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  108 bits (271), Expect = 4e-24
 Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 29/247 (11%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL--AVDPAILLIVVGVLMFLLT 79
           VKYL+F FN+LFW+    ++ VG++    + + A L+    ++  A LLI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHY-- 137
           F GC+G+++EN CLL TF L L  VFLL+    IL F ++DK      + +   +  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 138 RDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQA 197
           + ++ L N     Q  F CCG  +Y DW +   +N +          VP SCCL      
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE--VYNATR---------VPDSCCLE----- 172

Query: 198 VINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLS 257
             +  CG        L A    +   C + +  W+  NL  +G   L  A+ Q++G+  +
Sbjct: 173 -FSESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223

Query: 258 QILVNQI 264
             +  Q+
Sbjct: 224 MTMYCQV 230


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  108 bits (271), Expect = 4e-24
 Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 29/247 (11%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL--AVDPAILLIVVGVLMFLLT 79
           VKYL+F FN+LFW+    ++ VG++    + + A L+    ++  A LLI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHY-- 137
           F GC+G+++EN CLL TF L L  VFLL+    IL F ++DK      + +   +  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 138 RDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQA 197
           + ++ L N     Q  F CCG  +Y DW +   +N +          VP SCCL      
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE--VYNATR---------VPDSCCLE----- 172

Query: 198 VINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLS 257
             +  CG        L A    +   C + +  W+  NL  +G   L  A+ Q++G+  +
Sbjct: 173 -FSESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223

Query: 258 QILVNQI 264
             +  Q+
Sbjct: 224 MTMYCQV 230


>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  108 bits (271), Expect = 4e-24
 Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 29/247 (11%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL--AVDPAILLIVVGVLMFLLT 79
           VKYL+F FN+LFW+    ++ VG++    + + A L+    ++  A LLI+ G  +  + 
Sbjct: 9   VKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIG 68

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHY-- 137
           F GC+G+++EN CLL TF L L  VFLL+    IL F ++DK      + +   +  Y  
Sbjct: 69  FVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGT 128

Query: 138 RDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQA 197
           + ++ L N     Q  F CCG  +Y DW +   +N +          VP SCCL      
Sbjct: 129 QGNVGLTNAWSIIQTDFRCCGVSNYTDWFE--VYNATR---------VPDSCCLE----- 172

Query: 198 VINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLS 257
             +  CG        L A    +   C + +  W+  NL  +G   L  A+ Q++G+  +
Sbjct: 173 -FSESCG--------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFA 223

Query: 258 QILVNQI 264
             +  Q+
Sbjct: 224 MTMYCQV 230


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score =  108 bits (270), Expect = 5e-24
 Identities = 65/247 (26%), Positives = 120/247 (48%), Gaps = 29/247 (11%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMK--HAEAALACLAVDPAILLIVVGVLMFLLT 79
           +KY++F FN++FW+    ++ VG++  + +   A  + +  ++  A L+I +G ++ +  
Sbjct: 9   LKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTG 68

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIV--HY 137
           F GC+G+++EN CLL +F + L  + L +L   IL FV+ DK      + +   ++  H 
Sbjct: 69  FLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLYHT 128

Query: 138 RDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQA 197
            +++ L+N  +  Q +  CCG   Y DW            P     +VP  CC+      
Sbjct: 129 ENNVGLKNAWNIIQAEMRCCGVTDYTDW-----------YPVLGENTVPDRCCMEN---- 173

Query: 198 VINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLS 257
             +  CG+         A+  ++  GC +K+  W   N  +LG V + + I Q++G+  S
Sbjct: 174 --SQGCGR--------NATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFS 223

Query: 258 QILVNQI 264
             L   I
Sbjct: 224 MTLFQHI 230


>gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]
          Length = 147

 Score =  107 bits (267), Expect = 1e-23
 Identities = 44/110 (40%), Positives = 72/110 (65%)

Query: 156 CCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVINTMCGQGMQAFDYLEA 215
           CCG    +DW  N+YFNCS  + SRE+C VP+SCC+P P Q V+NT CG  ++     + 
Sbjct: 30  CCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQLKSKW 89

Query: 216 SKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILVNQIK 265
            + I+T GCI  L +W+  N++++ GV + +++ Q+ GI L++ L++ I+
Sbjct: 90  DESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIE 139


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score =  107 bits (266), Expect = 2e-23
 Identities = 73/260 (28%), Positives = 129/260 (49%), Gaps = 42/260 (16%)

Query: 18  VSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALAC--------LAVDPAILLI 69
           VS  +KY +F FN LFW+  ++++A+ ++ R+   ++A            +AVD   +LI
Sbjct: 4   VSACIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVD---ILI 60

Query: 70  VVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEI 129
            VG ++ +L F GC G+++E+ C+L  F + L  + LLQ+A GILG VF  K+   V+E 
Sbjct: 61  AVGAIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNET 120

Query: 130 I--NNAIVHY--RDDLDLQNLIDFGQKKFSCCGGIS-YKDWSQNMYFNCSEDNPSRERCS 184
           +  N  ++      +   Q  I   Q++F CCG ++   DW  N      +  P    C 
Sbjct: 121 LYENTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNF-----QHYPELCACL 175

Query: 185 VPYSCCLPTPDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVAL 244
                C                 Q+++     K +Y   CI  + +++  NL ++ G++ 
Sbjct: 176 DKQRPC-----------------QSYN----GKQVYKETCISFIKDFLAKNLIIVIGISF 214

Query: 245 GLAIPQLVGILLSQILVNQI 264
           GLA+ +++G++ S +L  QI
Sbjct: 215 GLAVIEILGLVFSMVLYCQI 234


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  105 bits (263), Expect = 3e-23
 Identities = 65/249 (26%), Positives = 121/249 (48%), Gaps = 20/249 (8%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA--VDPAILLIVVGVLMFLLT 79
           +KYLLF +N  FW+  + ++AVG++   +K    +L      +  A +L+V G ++ +  
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTG 75

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIV---H 136
             GC  + +E   LL+ + + L  +FLL++ AGIL + +  +   ++ E + + +    H
Sbjct: 76  VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYH 135

Query: 137 YRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQ 196
                 + + +D  Q++F CCG  + +DW  + +    E         VP SCC      
Sbjct: 136 QPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGR----VVPDSCC------ 185

Query: 197 AVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILL 256
             +  +CGQ   A +  +        GCI KL  +I  +L ++G V +G+A  Q+ G++ 
Sbjct: 186 KTVVALCGQRDHASNIYKVE-----GGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIF 240

Query: 257 SQILVNQIK 265
           +  L   +K
Sbjct: 241 TCCLYRSLK 249


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  105 bits (263), Expect = 3e-23
 Identities = 65/249 (26%), Positives = 121/249 (48%), Gaps = 20/249 (8%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA--VDPAILLIVVGVLMFLLT 79
           +KYLLF +N  FW+  + ++AVG++   +K    +L      +  A +L+V G ++ +  
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTG 75

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIV---H 136
             GC  + +E   LL+ + + L  +FLL++ AGIL + +  +   ++ E + + +    H
Sbjct: 76  VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYH 135

Query: 137 YRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQ 196
                 + + +D  Q++F CCG  + +DW  + +    E         VP SCC      
Sbjct: 136 QPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGR----VVPDSCC------ 185

Query: 197 AVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILL 256
             +  +CGQ   A +  +        GCI KL  +I  +L ++G V +G+A  Q+ G++ 
Sbjct: 186 KTVVALCGQRDHASNIYKVE-----GGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIF 240

Query: 257 SQILVNQIK 265
           +  L   +K
Sbjct: 241 TCCLYRSLK 249


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  105 bits (263), Expect = 3e-23
 Identities = 65/249 (26%), Positives = 121/249 (48%), Gaps = 20/249 (8%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA--VDPAILLIVVGVLMFLLT 79
           +KYLLF +N  FW+  + ++AVG++   +K    +L      +  A +L+V G ++ +  
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTG 75

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIV---H 136
             GC  + +E   LL+ + + L  +FLL++ AGIL + +  +   ++ E + + +    H
Sbjct: 76  VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYH 135

Query: 137 YRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQ 196
                 + + +D  Q++F CCG  + +DW  + +    E         VP SCC      
Sbjct: 136 QPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGR----VVPDSCC------ 185

Query: 197 AVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILL 256
             +  +CGQ   A +  +        GCI KL  +I  +L ++G V +G+A  Q+ G++ 
Sbjct: 186 KTVVALCGQRDHASNIYKVE-----GGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIF 240

Query: 257 SQILVNQIK 265
           +  L   +K
Sbjct: 241 TCCLYRSLK 249


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  105 bits (263), Expect = 3e-23
 Identities = 65/249 (26%), Positives = 121/249 (48%), Gaps = 20/249 (8%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA--VDPAILLIVVGVLMFLLT 79
           +KYLLF +N  FW+  + ++AVG++   +K    +L      +  A +L+V G ++ +  
Sbjct: 16  LKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTG 75

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIV---H 136
             GC  + +E   LL+ + + L  +FLL++ AGIL + +  +   ++ E + + +    H
Sbjct: 76  VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYH 135

Query: 137 YRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQ 196
                 + + +D  Q++F CCG  + +DW  + +    E         VP SCC      
Sbjct: 136 QPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGR----VVPDSCC------ 185

Query: 197 AVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILL 256
             +  +CGQ   A +  +        GCI KL  +I  +L ++G V +G+A  Q+ G++ 
Sbjct: 186 KTVVALCGQRDHASNIYKVE-----GGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIF 240

Query: 257 SQILVNQIK 265
           +  L   +K
Sbjct: 241 TCCLYRSLK 249


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score =  104 bits (260), Expect = 8e-23
 Identities = 72/260 (27%), Positives = 131/260 (50%), Gaps = 21/260 (8%)

Query: 21  LVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDP----AILLIVVGVLMF 76
           + KY LF FN++F+++  V++  GV+    K +  ++   +       A + I VG +  
Sbjct: 8   VTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTM 67

Query: 77  LLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH 136
           L+ F GCIG++ E  CLL  +   L  + + Q+ AG L +    K + ++  I+   I  
Sbjct: 68  LMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRD 127

Query: 137 Y---RDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPT 193
           Y   R+D  LQ+  D+ Q +  CCG +S+ +W+ N       +  +R   + P SC +  
Sbjct: 128 YNSSRED-SLQDAWDYVQAQVKCCGWVSFYNWTDN------AELMNRPEVTYPCSCEVKG 180

Query: 194 PDQ---AVINTMC---GQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLA 247
            +    +V    C   G   Q+ ++ E    +Y  GC++K+  W+  NL ++ GV +G+A
Sbjct: 181 EEDNSLSVRKGFCEAPGNRTQSGNHPE-DWPVYQEGCMEKVQAWLQENLGIILGVGVGVA 239

Query: 248 IPQLVGILLSQILVNQIKDQ 267
           I +L+G++LS  L   +  +
Sbjct: 240 IIELLGMVLSICLCRHVHSE 259


>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score =  101 bits (252), Expect = 6e-22
 Identities = 64/244 (26%), Positives = 116/244 (47%), Gaps = 26/244 (10%)

Query: 23  KYLLFFFNMLFWVISMVMVAVGVYARL-MKHAEAALACLAVDPAILLIVVGVLMFLLTFC 81
           K +L  +  +FW+  ++++AVG++ ++ +++  + L   A +   +LI  G ++ LL   
Sbjct: 18  KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLGTF 77

Query: 82  GCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDL 141
           GC  + R +  +L+ +++ LT VFL++L A I+GFVF  + +         A+  Y    
Sbjct: 78  GCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTG 137

Query: 142 DLQ-NLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVIN 200
           D + + +D  Q    CCG   Y+DW+   Y+  SE    +  C +    C P  D   +N
Sbjct: 138 DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYY--SEKGFPKSCCKL--EDCTPQRDADKVN 193

Query: 201 TMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQIL 260
                                 GC  K++  I S + ++ G++ G+A  QL+GI L+  L
Sbjct: 194 --------------------NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCL 233

Query: 261 VNQI 264
              I
Sbjct: 234 SRAI 237


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score =  100 bits (249), Expect = 1e-21
 Identities = 69/249 (27%), Positives = 114/249 (45%), Gaps = 20/249 (8%)

Query: 22  VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAV--DPAILLIVVGVLMFLLT 79
           +KYLLF FN  FWV    ++AVG++  + K    ++   +     A +LI  GVL+ +  
Sbjct: 16  LKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTG 75

Query: 80  FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRD 139
           F G    L E    L T+   L  +FL++L AG+L  V+  +   ++ + +N  +     
Sbjct: 76  FLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYG 135

Query: 140 D---LDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQ 196
                 +   +D  Q+ F CCG  S  DW  + Y    E     E   VP SCC      
Sbjct: 136 QPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLRE----AEGRQVPDSCC------ 185

Query: 197 AVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILL 256
             +   CGQ     +  +        GC+ KL  ++  +L L+G V +G+A  Q+ G++L
Sbjct: 186 KTVVVRCGQRAHPSNIYKVE-----GGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVL 240

Query: 257 SQILVNQIK 265
           +  L  +++
Sbjct: 241 TCCLHQRLQ 249


>gi|10834972 CD53 antigen [Homo sapiens]
          Length = 219

 Score = 94.4 bits (233), Expect = 1e-19
 Identities = 61/248 (24%), Positives = 105/248 (42%), Gaps = 49/248 (19%)

Query: 21  LVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPAILL----IVVGVLMF 76
           L+KY+LFFFN+LFW+    ++  G+Y  +  +       L   P++ L    ++VG ++ 
Sbjct: 8   LLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNL---PSLTLGNVFVIVGSIIM 64

Query: 77  LLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH 136
           ++ F GC+GS++EN CLL +F + L  + L ++   IL FV+  K    V++ + ++I  
Sbjct: 65  VVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHR 124

Query: 137 YRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQ 196
           Y  D   +   D  Q    CCG     DW+     +C  D                    
Sbjct: 125 YHSDNSTKAAWDSIQSFLQCCGINGTSDWTSGPPASCPSDRK------------------ 166

Query: 197 AVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILL 256
                                     GC  K   W HSN   +G + + + + +++G+  
Sbjct: 167 ------------------------VEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSF 202

Query: 257 SQILVNQI 264
           +  L  QI
Sbjct: 203 ALTLNCQI 210


>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
           sapiens]
          Length = 253

 Score = 94.4 bits (233), Expect = 1e-19
 Identities = 65/243 (26%), Positives = 110/243 (45%), Gaps = 22/243 (9%)

Query: 23  KYLLFFFNMLFWVISMVMVAVGVYARLM--KHAEAALACLAVDPAILLIVVGVLMFLLTF 80
           K +L F N++FW  + ++  VG Y  +    +         + PA+++I VG L+F++  
Sbjct: 10  KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGL 69

Query: 81  CGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYR-- 138
            GC  ++RE+ C L TF + L  VF+ ++   +LG+V+  K   +V   I      Y   
Sbjct: 70  IGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGT 129

Query: 139 DDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAV 198
           +       ID+ Q++  CCG  +Y DW    +F  +++       SVP SCC  T     
Sbjct: 130 NPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQ------SVPLSCCRETASN-- 181

Query: 199 INTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQ 258
               C         L     +Y  GC   +V  +   +  +   AL  A  QL+G+L + 
Sbjct: 182 ----CNGS------LAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231

Query: 259 ILV 261
           I++
Sbjct: 232 IVL 234


>gi|91106727 CD53 antigen [Homo sapiens]
          Length = 219

 Score = 94.4 bits (233), Expect = 1e-19
 Identities = 61/248 (24%), Positives = 105/248 (42%), Gaps = 49/248 (19%)

Query: 21  LVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPAILL----IVVGVLMF 76
           L+KY+LFFFN+LFW+    ++  G+Y  +  +       L   P++ L    ++VG ++ 
Sbjct: 8   LLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNL---PSLTLGNVFVIVGSIIM 64

Query: 77  LLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH 136
           ++ F GC+GS++EN CLL +F + L  + L ++   IL FV+  K    V++ + ++I  
Sbjct: 65  VVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHR 124

Query: 137 YRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQ 196
           Y  D   +   D  Q    CCG     DW+     +C  D                    
Sbjct: 125 YHSDNSTKAAWDSIQSFLQCCGINGTSDWTSGPPASCPSDRK------------------ 166

Query: 197 AVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILL 256
                                     GC  K   W HSN   +G + + + + +++G+  
Sbjct: 167 ------------------------VEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSF 202

Query: 257 SQILVNQI 264
           +  L  QI
Sbjct: 203 ALTLNCQI 210


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.142    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,228,582
Number of Sequences: 37866
Number of extensions: 427772
Number of successful extensions: 1555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1399
Number of HSP's gapped (non-prelim): 66
length of query: 283
length of database: 18,247,518
effective HSP length: 101
effective length of query: 182
effective length of database: 14,423,052
effective search space: 2624995464
effective search space used: 2624995464
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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