Search of human proteins with 30410794

Search of human proteins with 30410794

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30410794 proteasome activator subunit 3 isoform 1 [Homo
sapiens]
         (254 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30410794 proteasome activator subunit 3 isoform 1 [Homo sapiens]   499   e-141
gi|30410796 proteasome activator subunit 3 isoform 2 [Homo sapiens]   489   e-139
gi|5453990 proteasome activator subunit 1 isoform 1 [Homo sapiens]    204   5e-53
gi|30581141 proteasome activator subunit 1 isoform 2 [Homo sapiens]   180   1e-45
gi|30410792 proteasome activator subunit 2 [Homo sapiens]             163   2e-40
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     35   0.048
gi|31982906 cingulin-like 1 [Homo sapiens]                             30   1.6  
gi|30065649 protein phosphatase 2A, regulatory subunit B' isofor...    30   2.0  
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               29   4.5  
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]                29   4.5  
gi|158341646 hypothetical protein LOC729830 [Homo sapiens]             29   4.5  
gi|189163504 serine peptidase inhibitor, Kazal type 5 isoform c ...    28   5.9  
gi|74027261 serine peptidase inhibitor, Kazal type 5 isoform b p...    28   5.9  
gi|189163501 serine peptidase inhibitor, Kazal type 5 isoform a ...    28   5.9  
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ...    28   7.7  
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ...    28   7.7  

>gi|30410794 proteasome activator subunit 3 isoform 1 [Homo sapiens]
          Length = 254

 Score =  499 bits (1284), Expect = e-141
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS 60
           MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS
Sbjct: 1   MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS 60

Query: 61  DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE 120
           DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE
Sbjct: 61  DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE 120

Query: 121 KVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS 180
           KVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS
Sbjct: 121 KVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS 180

Query: 181 RYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIE 240
           RYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIE
Sbjct: 181 RYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIE 240

Query: 241 KIKRPRSSNAETLY 254
           KIKRPRSSNAETLY
Sbjct: 241 KIKRPRSSNAETLY 254


>gi|30410796 proteasome activator subunit 3 isoform 2 [Homo sapiens]
          Length = 267

 Score =  489 bits (1260), Expect = e-139
 Identities = 254/267 (95%), Positives = 254/267 (95%), Gaps = 13/267 (4%)

Query: 1   MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS 60
           MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS
Sbjct: 1   MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHS 60

Query: 61  DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE 120
           DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE
Sbjct: 61  DMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIE 120

Query: 121 KVKPEIRLLIEKCNT-------------VKMWVQLLIPRIEDGNNFGVSIQEETVAELRT 167
           KVKPEIRLLIEKCNT             VKMWVQLLIPRIEDGNNFGVSIQEETVAELRT
Sbjct: 121 KVKPEIRLLIEKCNTPSGKGPHICFDLQVKMWVQLLIPRIEDGNNFGVSIQEETVAELRT 180

Query: 168 VESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQ 227
           VESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQ
Sbjct: 181 VESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQ 240

Query: 228 YVTLHDMILKNIEKIKRPRSSNAETLY 254
           YVTLHDMILKNIEKIKRPRSSNAETLY
Sbjct: 241 YVTLHDMILKNIEKIKRPRSSNAETLY 267


>gi|5453990 proteasome activator subunit 1 isoform 1 [Homo sapiens]
          Length = 249

 Score =  204 bits (520), Expect = 5e-53
 Identities = 102/253 (40%), Positives = 166/253 (65%), Gaps = 6/253 (2%)

Query: 3   SLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDM 62
           ++L+V  E + KVD FRE + ++ E+L+ ++FPKK+ ELD+FLKEP LN  +L+ + + +
Sbjct: 2   AMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPL 61

Query: 63  NLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPN-GMLKSNQQLVDIIEK 121
           ++PVPDP+      +       K++  ++ +E  +G      P  G +  N+++V ++++
Sbjct: 62  DIPVPDPVKEKEKEE-----RKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQR 116

Query: 122 VKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISR 181
           +KPEI+ +IE+ N V  W+QL IPRIEDGNNFGV++QE+    + ++ ++   +  QIS+
Sbjct: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISK 176

Query: 182 YYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEK 241
           Y+  R   V+K AK PHV DYR+ V E+DE EY  +RL++ E+RN Y  L+D+ILKN EK
Sbjct: 177 YFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEK 236

Query: 242 IKRPRSSNAETLY 254
           +K+PR      +Y
Sbjct: 237 LKKPRGETKGMIY 249


>gi|30581141 proteasome activator subunit 1 isoform 2 [Homo sapiens]
          Length = 250

 Score =  180 bits (456), Expect = 1e-45
 Identities = 91/228 (39%), Positives = 150/228 (65%), Gaps = 6/228 (2%)

Query: 3   SLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDM 62
           ++L+V  E + KVD FRE + ++ E+L+ ++FPKK+ ELD+FLKEP LN  +L+ + + +
Sbjct: 2   AMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPL 61

Query: 63  NLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPN-GMLKSNQQLVDIIEK 121
           ++PVPDP+      +       K++  ++ +E  +G      P  G +  N+++V ++++
Sbjct: 62  DIPVPDPVKEKEKEE-----RKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQR 116

Query: 122 VKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISR 181
           +KPEI+ +IE+ N V  W+QL IPRIEDGNNFGV++QE+    + ++ ++   +  QIS+
Sbjct: 117 LKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHTQISK 176

Query: 182 YYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYV 229
           Y+  R   V+K AK PHV DYR+ V E+DE EY  +RL++ E+RN YV
Sbjct: 177 YFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYV 224


>gi|30410792 proteasome activator subunit 2 [Homo sapiens]
          Length = 239

 Score =  163 bits (412), Expect = 2e-40
 Identities = 84/250 (33%), Positives = 144/250 (57%), Gaps = 17/250 (6%)

Query: 5   LKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNL 64
           +++  E + +V+ FR+ +  EAE+ +  F P+K++ L+  L+E  LN+ DLT + + +++
Sbjct: 7   VRLSGEARKQVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSLRAPLDI 66

Query: 65  PVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKP 124
           P+PDP       D ++    +K+ + +C              G L  N++++ ++  VKP
Sbjct: 67  PIPDP---PPKDDEMETDKQEKKEVHKC--------------GFLPGNEKVLSLLALVKP 109

Query: 125 EIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYI 184
           E+  L EKC  V  W+Q LIP+IEDGN+FGV+IQE+ +  +  V+++  ++   IS+Y+ 
Sbjct: 110 EVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTISKYFS 169

Query: 185 TRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKR 244
            R   V+K +K  HV DYR  V E DE  Y  LR ++ +LR  Y  L+ +I  N+EKI  
Sbjct: 170 ERGDAVAKASKETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSNLEKIVN 229

Query: 245 PRSSNAETLY 254
           P+     ++Y
Sbjct: 230 PKGEEKPSMY 239


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 35.4 bits (80), Expect = 0.048
 Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 11/120 (9%)

Query: 87  RRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLL------IEKCNTVKMWV 140
           + +   EE F+ ++  V+     K+   +    ++V    RLL      IE C  +   +
Sbjct: 271 KNMQNAEEWFK-SRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEAL 329

Query: 141 QLLIPRIEDGNNFGVSIQEETV----AELRTVESEAASYLDQISRYYITRAKLVSKIAKY 196
           +  +  +ED  N  +S  ++T+     ELRT +SE A YL +       +  L  +IA Y
Sbjct: 330 EKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAY 389


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 41/204 (20%), Positives = 89/204 (43%), Gaps = 29/204 (14%)

Query: 72   LTNSHDGLDGPTYKKRRLDEC--EEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLL 129
            L  +   L   T ++++L E   EE+ Q  ++  + N M      L   IEK++ E+  +
Sbjct: 901  LEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADI 960

Query: 130  IEKCNTVKMWVQLLIPRIEDGNNFGVS-----IQEETVA-------------ELRTVESE 171
            +E   T  + +Q  +   ++ N   ++     ++E+T+              E+R +E E
Sbjct: 961  VEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEE 1020

Query: 172  AASYLDQISRYYITRAKLVSKIAK--------YPHVEDYRRTVTEIDEKEYISLRLIISE 223
               Y  +     +T+ +L+ +  K          H++D R  + +  E +   L + + E
Sbjct: 1021 LRDY-QRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEE 1079

Query: 224  LRNQYVTLHDMILKNIEKIKRPRS 247
             RN    L + I ++ E++++ R+
Sbjct: 1080 ERNNSDLLSERISRSREQMEQLRN 1103


>gi|30065649 protein phosphatase 2A, regulatory subunit B' isoform d
           [Homo sapiens]
          Length = 281

 Score = 30.0 bits (66), Expect = 2.0
 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 4/52 (7%)

Query: 4   LLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLL----ELDSFLKEPILN 51
           +L +++ VK K  +F  R++ EAE+LVA   P  L     E+  +LKE + N
Sbjct: 52  ILTLNEGVKGKKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGN 103


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 28.9 bits (63), Expect = 4.5
 Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 10/112 (8%)

Query: 36   KKLLELDSFLKEPILNIHDLTQIHSDMNLPVP-----DPILLTNSHD--GLDGPTYKKRR 88
            K L +L   +K+  + + D TQ++SD+   V      + +L +   D   L   T + RR
Sbjct: 1653 KSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRR 1712

Query: 89   LDECE--EAFQGTKVFVMPN-GMLKSNQQLVDIIEKVKPEIRLLIEKCNTVK 137
            L E E  EA +   +F   N  +L   ++L   + +++ E   ++++C   +
Sbjct: 1713 LSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAE 1764


>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
          Length = 2186

 Score = 28.9 bits (63), Expect = 4.5
 Identities = 16/64 (25%), Positives = 28/64 (43%)

Query: 73   TNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEK 132
            T+SH+G      +   +   + A    K+  M +  + SN   +DI+  V  E  +  E 
Sbjct: 1427 TSSHEGHKQHRSQTLPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEV 1486

Query: 133  CNTV 136
            C T+
Sbjct: 1487 CLTI 1490


>gi|158341646 hypothetical protein LOC729830 [Homo sapiens]
          Length = 1040

 Score = 28.9 bits (63), Expect = 4.5
 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 17/77 (22%)

Query: 25  EAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLD---G 81
           E+E+L+A +        D  +KE       L +     N P PDP+LLT   +G +   G
Sbjct: 747 ESEELIAQY--------DQIIKELDSGAEGLME----QNYPTPDPLLLTKEEEGKEESKG 794

Query: 82  PTYK--KRRLDECEEAF 96
              K  K+ L++ E+ F
Sbjct: 795 EKEKEGKKELEDEEDDF 811


>gi|189163504 serine peptidase inhibitor, Kazal type 5 isoform c
           precursor [Homo sapiens]
          Length = 916

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 16/50 (32%), Positives = 23/50 (46%)

Query: 78  GLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIR 127
           G DG TY  R     E A  G+++ V   G  KS+    D+    +P +R
Sbjct: 120 GTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVR 169


>gi|74027261 serine peptidase inhibitor, Kazal type 5 isoform b
           precursor [Homo sapiens]
          Length = 1064

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 16/50 (32%), Positives = 23/50 (46%)

Query: 78  GLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIR 127
           G DG TY  R     E A  G+++ V   G  KS+    D+    +P +R
Sbjct: 120 GTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVR 169


>gi|189163501 serine peptidase inhibitor, Kazal type 5 isoform a
           precursor [Homo sapiens]
          Length = 1094

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 16/50 (32%), Positives = 23/50 (46%)

Query: 78  GLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIR 127
           G DG TY  R     E A  G+++ V   G  KS+    D+    +P +R
Sbjct: 120 GTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVR 169


>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
           sapiens]
          Length = 833

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 13/100 (13%)

Query: 165 LRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISL------R 218
           LR +E E  +  +   +Y +T AKL++ + +      Y   V  +   +Y+ L       
Sbjct: 373 LRQMERERKAMAE---KYIMTSAKLIAPVIETSFAAGYDWCVEVVKASQYVELANDLEIN 429

Query: 219 LIISELR----NQYVTLHDMILKNIEKIKRPRSSNAETLY 254
             ++ LR    NQ V +  ++ K   ++K   ++N   LY
Sbjct: 430 KAVTYLRQKDYNQAVEILKVLEKKDSRVKSAAATNLSALY 469


>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
           sapiens]
          Length = 824

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 13/100 (13%)

Query: 165 LRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISL------R 218
           LR +E E  +  +   +Y +T AKL++ + +      Y   V  +   +Y+ L       
Sbjct: 364 LRQMERERKAMAE---KYIMTSAKLIAPVIETSFAAGYDWCVEVVKASQYVELANDLEIN 420

Query: 219 LIISELR----NQYVTLHDMILKNIEKIKRPRSSNAETLY 254
             ++ LR    NQ V +  ++ K   ++K   ++N   LY
Sbjct: 421 KAVTYLRQKDYNQAVEILKVLEKKDSRVKSAAATNLSALY 460


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,470,217
Number of Sequences: 37866
Number of extensions: 361163
Number of successful extensions: 1067
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1054
Number of HSP's gapped (non-prelim): 18
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.