Guide to the Human Genome
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Search of human proteins with 122937299

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]
         (1146 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]       2296   0.0  
gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]        175   2e-43
gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]       171   4e-42
gi|14251207 MOV10-like 1 [Homo sapiens]                               112   2e-24
gi|113722133 senataxin [Homo sapiens]                                 102   2e-21
gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]         91   8e-18
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ...    90   1e-17
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ...    90   1e-17
gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sap...    86   3e-16
gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapi...    86   3e-16
gi|38788372 aquarius [Homo sapiens]                                    81   5e-15
gi|54792138 helicase with zinc finger domain [Homo sapiens]            80   1e-14
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]           35   0.53 
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]             35   0.53 
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             32   2.6  
gi|70980531 GGA binding partner [Homo sapiens]                         32   4.5  
gi|105990532 apolipoprotein B precursor [Homo sapiens]                 31   5.9  
gi|239756892 PREDICTED: hypothetical protein [Homo sapiens]            31   7.7  
gi|239751388 PREDICTED: hypothetical protein XP_002347834 [Homo ...    31   7.7  
gi|239745895 PREDICTED: hypothetical protein XP_002343612 [Homo ...    31   7.7  
gi|55741661 hypothetical protein LOC57653 [Homo sapiens]               31   7.7  

>gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]
          Length = 1146

 Score = 2296 bits (5949), Expect = 0.0
 Identities = 1146/1146 (100%), Positives = 1146/1146 (100%)

Query: 1    MKTPCIPSPKQGSKGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQARAF 60
            MKTPCIPSPKQGSKGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQARAF
Sbjct: 1    MKTPCIPSPKQGSKGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQARAF 60

Query: 61   FPFLSFLCYPRFRCLFCLQFAIPASRMEQLNELELLMEKSFWEEAELPAELFQKKVVASF 120
            FPFLSFLCYPRFRCLFCLQFAIPASRMEQLNELELLMEKSFWEEAELPAELFQKKVVASF
Sbjct: 61   FPFLSFLCYPRFRCLFCLQFAIPASRMEQLNELELLMEKSFWEEAELPAELFQKKVVASF 120

Query: 121  PRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVPVEPG 180
            PRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVPVEPG
Sbjct: 121  PRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVPVEPG 180

Query: 181  DIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSDPATR 240
            DIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSDPATR
Sbjct: 181  DIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSDPATR 240

Query: 241  QMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYL 300
            QMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYL
Sbjct: 241  QMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYL 300

Query: 301  PSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKG 360
            PSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKG
Sbjct: 301  PSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKG 360

Query: 361  KIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEAGLLL 420
            KIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEAGLLL
Sbjct: 361  KIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEAGLLL 420

Query: 421  YLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCK 480
            YLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCK
Sbjct: 421  YLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCK 480

Query: 481  YCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQS 540
            YCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQS
Sbjct: 481  YCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQS 540

Query: 541  KDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMA 600
            KDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMA
Sbjct: 541  KDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMA 600

Query: 601  GDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTP 660
            GDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTP
Sbjct: 601  GDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTP 660

Query: 661  LGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAM 720
            LGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAM
Sbjct: 661  LGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAM 720

Query: 721  KKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKI 780
            KKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKI
Sbjct: 721  KKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKI 780

Query: 781  GFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRK 840
            GFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRK
Sbjct: 781  GFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRK 840

Query: 841  IFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLE 900
            IFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLE
Sbjct: 841  IFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLE 900

Query: 901  QNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYA 960
            QNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYA
Sbjct: 901  QNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYA 960

Query: 961  DYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSP 1020
            DYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSP
Sbjct: 961  DYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSP 1020

Query: 1021 SDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELL 1080
            SDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELL
Sbjct: 1021 SDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELL 1080

Query: 1081 KDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESLCHIL 1140
            KDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESLCHIL
Sbjct: 1081 KDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESLCHIL 1140

Query: 1141 GDFQRE 1146
            GDFQRE
Sbjct: 1141 GDFQRE 1146


>gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]
          Length = 1118

 Score =  175 bits (444), Expect = 2e-43
 Identities = 137/465 (29%), Positives = 231/465 (49%), Gaps = 74/465 (15%)

Query: 709  LKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFS-VLLTSYTHSA 767
            L  LN  Q  A+K VL  +  +LI G PGTGKT T  T+V  L   G   VL+ + ++ A
Sbjct: 468  LPDLNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIA 526

Query: 768  VDNILLKLAKFKIGFLRL------------------------------GQIQKVHPAIQQ 797
            VD +  K+ +  +  +RL                               ++Q++     +
Sbjct: 527  VDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGE 586

Query: 798  FTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPI 857
             +  +  R +++K  A  E L N+  ++  TC+G   P  ++  F   ++DE++Q ++P 
Sbjct: 587  LSSADEKRYRALKRTAERELLMNAD-VICCTCVGAGDPRLAKMQFRSILIDESTQATEPE 645

Query: 858  CLGPLFF-SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMN 916
            C+ P+   +++ +LVGDH QL P+V+ ++A   G+S+SLF+RL       ++L VQYRM+
Sbjct: 646  CMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMH 705

Query: 917  SKIMSLSNKLTYEGKLECG---SDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFE 973
              + +  + + YEG L+ G   +D+V                        D  W     +
Sbjct: 706  PALSAFPSNIFYEGSLQNGVTAADRVKKGF--------------------DFQWP----Q 741

Query: 974  PNNPVCFLNTDKVPAPEQVEKGGVS--NVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYR- 1030
            P+ P+ F  T      E++   G S  N TEA  +  +T+  +KAG  P  IGII PY  
Sbjct: 742  PDKPMFFYVTQ---GQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEG 798

Query: 1031 ------QQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWR 1084
                  Q ++    L  +    VE+ +VD +QGR+K  +++S VR+N+   +G  L D R
Sbjct: 799  QRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIG-FLNDPR 857

Query: 1085 RLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLP 1129
            RLNVA+TRA++ +I++G   +L+  P    LLN+   +K++++ P
Sbjct: 858  RLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGP 902


>gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
          Length = 993

 Score =  171 bits (433), Expect = 4e-42
 Identities = 172/651 (26%), Positives = 288/651 (44%), Gaps = 102/651 (15%)

Query: 532  LMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKH- 590
            L L  +++ ++ +   +NI L    E++  G C+  L ++   +    G+ L  F+ +  
Sbjct: 17   LELERDAEVEERRSWQENISL---KELQSRGVCLLKL-QVSSQRTGLYGRLLVTFEPRRY 72

Query: 591  ---GAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFR 647
                A+P  +  +GD V +         L+ G +  +   +VT   D       ES  F+
Sbjct: 73   GSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFD-------ESHDFQ 125

Query: 648  LDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFRE------PQFISYL---SSVLP 698
            L  + +N         L KL  N    ++L+  +I  ++         I  L   S+  P
Sbjct: 126  LSLDRENSY------RLLKLA-NDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSP 178

Query: 699  HDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSV 758
                  +      L+  Q++A+   L  K+  +I G PGTGKTTT+  ++      G  V
Sbjct: 179  ASEIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKV 238

Query: 759  LLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQ--------------------- 797
            L  + ++ AVDN++ +LA  K   LRLG   ++  +IQQ                     
Sbjct: 239  LCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRK 298

Query: 798  -----FTEQEICRSKSIKS------------------LALLEELYNSQLIVAT-TCMGIN 833
                 F + +  + K  KS                   A+LE L ++ +++AT T    +
Sbjct: 299  DIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASAD 358

Query: 834  HPI--FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGM 891
             P+       FD  ++DE +Q  +  C  PL  +R+ +L GDH+QLPP  ++ +A   G+
Sbjct: 359  GPLKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGL 418

Query: 892  SESLFKRLEQNKSAVV--QLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHF 949
            S SL +RL +   A V   LTVQYRM+  IM  ++   Y G+L   S          RH 
Sbjct: 419  SLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVA-------RHL 471

Query: 950  KDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVS--NVTEAKLIV 1007
                          D P +    E   P+  ++T      E  E+   S  N  E +L+ 
Sbjct: 472  ------------LRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVS 519

Query: 1008 FLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSF 1067
                  V AG    DI +++PY  Q+ ++   L      +E+ +VD +QGR+K  V++SF
Sbjct: 520  LHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSF 579

Query: 1068 VRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNH 1118
            VRSN+ G VG L +D RR+NVA+TRA+  + ++    ++N +  L+ L+ +
Sbjct: 580  VRSNRKGEVGFLAED-RRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEY 629


>gi|14251207 MOV10-like 1 [Homo sapiens]
          Length = 1211

 Score =  112 bits (281), Expect = 2e-24
 Identities = 122/435 (28%), Positives = 203/435 (46%), Gaps = 77/435 (17%)

Query: 712  LNKPQRQAMKKVLLSKDYTL---IVGMPGTGKTTTICTLV-RILYACGFS-VLLTSYTHS 766
            LN+ Q+ A+K++L      L   + G PGTGKT TI   V ++ +A   S +L+ + ++S
Sbjct: 745  LNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPSNS 804

Query: 767  AVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALL------EELYN 820
            A D + L+L + K+  L+   + +V+           CR + I   A+       E+++ 
Sbjct: 805  AADLVCLRLHESKV--LQPATMVRVNAT---------CRFEEIVIDAVKPYCRDGEDIWK 853

Query: 821  SQL--IVATTCM--GINHPIFSRK-IFDFCIVDEASQISQPICLGPLFF----SRRFVLV 871
            +    I+ TTC   G+ + I  R   F    VDEA Q S+P CL PL      S + VL 
Sbjct: 854  ASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLA 913

Query: 872  GDHQQLPPLVLNREARALGMSESLFKRL-----------------EQNKSAVVQLTVQYR 914
            GD  QL P++ +R A A G++ S  +RL                   N   V +L   YR
Sbjct: 914  GDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYR 973

Query: 915  MNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFE 973
             +  ++ L ++L Y  +LE C    V  +++           L F+             E
Sbjct: 974  SHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSE-----ARE 1028

Query: 974  PNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQL 1033
              +P  F   + V               +      L +  + +  S SDIG+I PYR+Q+
Sbjct: 1029 GKSPSWFNPAEAV---------------QVLRYCCLLAHSISSQVSASDIGVITPYRKQV 1073

Query: 1034 KIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGE-----LLKDWRRL 1086
            + I  +L R++ +  ++V +V+++QG++  ++++S VRSN+D    +      L + +R 
Sbjct: 1074 EKIR-ILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRF 1132

Query: 1087 NVAITRAKHKLILLG 1101
            NVAITR K  LI+LG
Sbjct: 1133 NVAITRPKALLIVLG 1147


>gi|113722133 senataxin [Homo sapiens]
          Length = 2677

 Score =  102 bits (255), Expect = 2e-21
 Identities = 97/322 (30%), Positives = 147/322 (45%), Gaps = 62/322 (19%)

Query: 803  ICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPL 862
            IC + S     LLE  +  Q  V  +C+               IVDEA Q  +   L PL
Sbjct: 2151 ICCTLSTSGGLLLESAFRGQGGVPFSCV---------------IVDEAGQSCEIETLTPL 2195

Query: 863  FFS-RRFVLVGDHQQLPPLVLNREARALGMSESLFKR----LEQN-------KSAVVQLT 910
                 + +LVGD +QLPP V++ +A+  G  +S+  R    LE+N       +  ++QLT
Sbjct: 2196 IHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLT 2255

Query: 911  VQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMG 970
            VQYRM+  I    +   Y   L+      A               +   +D+   P+L  
Sbjct: 2256 VQYRMHPDICLFPSNYVYNRNLKTNRQTEA---------------IRCSSDWPFQPYL-- 2298

Query: 971  VFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFV--KAGCSPSDIGIIAP 1028
            VF+  +             E+ +     NV E KL++ +  +    +   S  +IGII  
Sbjct: 2299 VFDVGD-----------GSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITH 2347

Query: 1029 YRQQLKIINDLLARSI---GMVEVNTVDKYQGRDKSIVLVSFVRSNK-DGTVGELLKDWR 1084
            Y+ Q  +I   L +     G  EV+TVD +QGR K  V+V+ VR+N   G++G  L   +
Sbjct: 2348 YKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG-FLASLQ 2406

Query: 1085 RLNVAITRAKHKLILLGCVPSL 1106
            RLNV ITRAK+ L +LG + +L
Sbjct: 2407 RLNVTITRAKYSLFILGHLRTL 2428


>gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]
          Length = 1918

 Score = 90.5 bits (223), Expect = 8e-18
 Identities = 94/340 (27%), Positives = 155/340 (45%), Gaps = 41/340 (12%)

Query: 795  IQQFTEQEICRSKSIKSLALLEELY---NSQLIVATTCMGINHPIFSRKIFD-FCIVDEA 850
            I  +  Q    ++ +  L L E+L+   ++Q++  TT     +    +K+     IV+EA
Sbjct: 949  ILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEA 1008

Query: 851  SQISQPICLGPLFFS-RRFVLVGDHQQLPPLVLNRE-ARALGMSESLFKRLEQNKSAVVQ 908
            +++ +   +  L  + +  +L+GDHQQL P     + A+   +  SLF+RL +     V+
Sbjct: 1009 AEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVR 1068

Query: 909  LTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWL 968
            L  Q+RM  +I  L     Y+      S      V+     K V   L F+ +++     
Sbjct: 1069 LNYQHRMCPEIARLLTPHIYQDLENHPS------VLKYEKIKGVSSNL-FFVEHN----- 1116

Query: 969  MGVFEPNNPVCFLNTDKVPAPEQVEKGGVS--NVTEAKLIVFLTSIFVKAGCSPSDIGII 1026
                                PEQ  + G S  N  EA  +V L   F+     PS I I+
Sbjct: 1117 -------------------FPEQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITIL 1157

Query: 1027 APYRQQLKIINDLL-ARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRR 1085
              Y  QL  +  L+ A++   V V+ VDKYQG +  I+L+S VRSN++G VG  L+   R
Sbjct: 1158 TTYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSNQEGKVG-FLQISNR 1216

Query: 1086 LNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLI 1125
            + VA++RAK  +  +G +  L   P   K+++ L     I
Sbjct: 1217 ICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENNQI 1256



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 12/109 (11%)

Query: 712 LNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYA---------CGFSVLLTS 762
           L+  Q +A++   L+++  +I G PGTGKT     +V+ L             F +L+  
Sbjct: 598 LDDSQMEALQ-FALTRELAIIQGPPGTGKTYVGLKIVQALLTNESVWQISLQKFPILVVC 656

Query: 763 YTHSAVDNILLKLAKF-KIGFLRLGQIQKVHPAIQQFTEQEICRSKSIK 810
           YT+ A+D  L  +    K   +R+G  +     ++QFT +E+   +  +
Sbjct: 657 YTNHALDQFLEGIYNCQKTSIVRVGG-RSNSEILKQFTLRELRNKREFR 704


>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
            [Homo sapiens]
          Length = 2649

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 93/348 (26%), Positives = 155/348 (44%), Gaps = 43/348 (12%)

Query: 798  FTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDF--CIVDEASQISQ 855
            F+ +++   K +   A   EL   ++I+ T     +    S KI D    +VDEA   ++
Sbjct: 2311 FSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASA---SLKILDVRQILVDEAGMATE 2367

Query: 856  PICLGPLFF---SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQ 912
            P  L PL     + + VL+GDH+QL P+V N   + LG+  SLF+R  ++      L  Q
Sbjct: 2368 PETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAH---MLDTQ 2424

Query: 913  YRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVF 972
            YRM+  I +  +   Y+ KL+            LR    V      +A     P + G  
Sbjct: 2425 YRMHEGICAFPSVAFYKSKLKTWQ--------GLRRPPSVL----GHAGKESCPVIFGHV 2472

Query: 973  EPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLT-SIFVKAGCSPSDIGIIAPYRQ 1031
            + +     ++TD      +  +   +N+ E   +V +T  + +     P DI ++ PY  
Sbjct: 2473 QGHERSLLVSTD------EGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNA 2526

Query: 1032 QLKIINDLLAR-SIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGEL-LKDW------ 1083
            Q   I+  L R  I  V V+++ K QG +   VLVS VR+     + +   K W      
Sbjct: 2527 QASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLG 2586

Query: 1084 -----RRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLII 1126
                  ++NVA+TRA+  L L+G    L C P    LL+   +++ ++
Sbjct: 2587 FVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2634



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 88/413 (21%), Positives = 163/413 (39%), Gaps = 54/413 (13%)

Query: 731  LIVGMPGTGKTTTICTL-VRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGF------- 782
            LI G  GTGKT T+    + ++      VL+ ++T+SA D  + +     +         
Sbjct: 541  LIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATP 600

Query: 783  LRLGQIQKVHPAIQQFTEQEICRSKSIKSLA--LLEELYNSQLIVATTCMG--INHPIFS 838
            LR+    +        T Q  C +   ++       EL   +++V TT     +  P+  
Sbjct: 601  LRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVPV-- 658

Query: 839  RKIFDFCIVDEASQISQPICLGPLFFSR---RFVLVGDHQQLPPLVLNREARALGMSESL 895
               F   ++DEA+Q+ +   L PL ++    R VL GDH Q+ P + +  ARA     +L
Sbjct: 659  -GFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTL 716

Query: 896  FKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLE 955
              R          L + Y+  +  ++  ++L +     C      +A+++        + 
Sbjct: 717  LHR----------LFLCYQQETHEVARQSRLVFHENYRC-----TDAIVSF-------IS 754

Query: 956  LEFYADYSDNPWLMGVFEP---NNPVCFLNTDKVPAPEQ-----VEKGGVSNVTEAKLIV 1007
              FY    +     G   P   + P+ F +    P  +      +    ++ V E     
Sbjct: 755  RHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEA 814

Query: 1008 FLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSF 1067
            + T      G     I +++   Q   +  +L  R +G V V + +   GR   +V++S 
Sbjct: 815  YNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLST 874

Query: 1068 VRS-----NKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKL 1115
            V +     +      E   D R LN  +TRA+ +L+++G   +L  +    KL
Sbjct: 875  VHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKL 927


>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
            [Homo sapiens]
          Length = 2080

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 93/348 (26%), Positives = 155/348 (44%), Gaps = 43/348 (12%)

Query: 798  FTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDF--CIVDEASQISQ 855
            F+ +++   K +   A   EL   ++I+ T     +    S KI D    +VDEA   ++
Sbjct: 1742 FSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASA---SLKILDVRQILVDEAGMATE 1798

Query: 856  PICLGPLFF---SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQ 912
            P  L PL     + + VL+GDH+QL P+V N   + LG+  SLF+R  ++      L  Q
Sbjct: 1799 PETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAH---MLDTQ 1855

Query: 913  YRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVF 972
            YRM+  I +  +   Y+ KL+            LR    V      +A     P + G  
Sbjct: 1856 YRMHEGICAFPSVAFYKSKLKTWQ--------GLRRPPSVL----GHAGKESCPVIFGHV 1903

Query: 973  EPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLT-SIFVKAGCSPSDIGIIAPYRQ 1031
            + +     ++TD      +  +   +N+ E   +V +T  + +     P DI ++ PY  
Sbjct: 1904 QGHERSLLVSTD------EGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNA 1957

Query: 1032 QLKIINDLLAR-SIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGEL-LKDW------ 1083
            Q   I+  L R  I  V V+++ K QG +   VLVS VR+     + +   K W      
Sbjct: 1958 QASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLG 2017

Query: 1084 -----RRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLII 1126
                  ++NVA+TRA+  L L+G    L C P    LL+   +++ ++
Sbjct: 2018 FVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2065



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 68/317 (21%), Positives = 127/317 (40%), Gaps = 44/317 (13%)

Query: 817  ELYNSQLIVATTCMG--INHPIFSRKIFDFCIVDEASQISQPICLGPLFFSR---RFVLV 871
            EL   +++V TT     +  P+     F   ++DEA+Q+ +   L PL ++    R VL 
Sbjct: 68   ELARHRVVVTTTSQARELRVPV---GFFSHILIDEAAQMLECEALTPLAYASHGTRLVLA 124

Query: 872  GDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGK 931
            GDH Q+ P + +  ARA     +L  R          L + Y+  +  ++  ++L +   
Sbjct: 125  GDHMQVTPRLFS-VARARAAEHTLLHR----------LFLCYQQETHEVARQSRLVFHEN 173

Query: 932  LECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEP---NNPVCFLNTDKVPA 988
              C      +A+++        +   FY    +     G   P   + P+ F +    P 
Sbjct: 174  YRC-----TDAIVSF-------ISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPD 221

Query: 989  PEQ-----VEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARS 1043
             +      +    ++ V E     + T      G     I +++   Q   +  +L  R 
Sbjct: 222  RDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRD 281

Query: 1044 IGMVEVNTVDKYQGRDKSIVLVSFVRS-----NKDGTVGELLKDWRRLNVAITRAKHKLI 1098
            +G V V + +   GR   +V++S V +     +      E   D R LN  +TRA+ +L+
Sbjct: 282  LGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLV 341

Query: 1099 LLGCVPSLNCYPPLEKL 1115
            ++G   +L  +    KL
Sbjct: 342  VVGDAVALCSFGACGKL 358


>gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
          Length = 1003

 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 111/455 (24%), Positives = 196/455 (43%), Gaps = 66/455 (14%)

Query: 696  VLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT---LIVGMPGTGKTTTICTLVR--I 750
            +LP D K  +       N  Q QAM+ ++         +I G PGTGKT T+   ++  +
Sbjct: 483  LLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVV 542

Query: 751  LYACGFSVLLTSYTHSAVDNILLKL-AKFKIGFLRL----GQIQKVHPAIQQFTEQEICR 805
             +     +L  + ++S  D +  +L         RL      I+ V   I+     +  +
Sbjct: 543  KHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKK 602

Query: 806  SKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQP---ICLGPL 862
             + +       + Y   +    T   +    F    F    +DEA    +P   + +  L
Sbjct: 603  GEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGL 662

Query: 863  FFSR-------RFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSA---------- 905
               +       + VL GD +QL P++ +   +  G+  SL +RL    S           
Sbjct: 663  MEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDP 722

Query: 906  --VVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYS 963
              + +L   YR +  I+ + N+L YEG+L+  +D V       R  +   L  + +    
Sbjct: 723  QFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRE----RFCRWAGLPRQGFPIIF 778

Query: 964  DNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTE-AKLIVFLTSIFVKAGCSPSD 1022
                     E N+P  F        PE+      + VT   KL++  +S   KA  SP  
Sbjct: 779  HGVMGKDEREGNSPSFF-------NPEEA-----ATVTSYLKLLLAPSSKKGKARLSPRS 826

Query: 1023 IGIIAPYRQQLKIINDLLAR---------SIGMVEVNTVDKYQGRDKSIVLVSFVRSNK- 1072
            +G+I+PYR+Q++ I   + +          I  ++V +V+++QG+++S++L+S VRS++ 
Sbjct: 827  VGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQS 886

Query: 1073 ------DGTVGELLKDWRRLNVAITRAKHKLILLG 1101
                  D  +G  LK+ +R NVA+TRAK  LI++G
Sbjct: 887  FVQLDLDFNLG-FLKNPKRFNVAVTRAKALLIIVG 920


>gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
          Length = 1003

 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 111/455 (24%), Positives = 196/455 (43%), Gaps = 66/455 (14%)

Query: 696  VLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT---LIVGMPGTGKTTTICTLVR--I 750
            +LP D K  +       N  Q QAM+ ++         +I G PGTGKT T+   ++  +
Sbjct: 483  LLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVV 542

Query: 751  LYACGFSVLLTSYTHSAVDNILLKL-AKFKIGFLRL----GQIQKVHPAIQQFTEQEICR 805
             +     +L  + ++S  D +  +L         RL      I+ V   I+     +  +
Sbjct: 543  KHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKK 602

Query: 806  SKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQP---ICLGPL 862
             + +       + Y   +    T   +    F    F    +DEA    +P   + +  L
Sbjct: 603  GEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGL 662

Query: 863  FFSR-------RFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSA---------- 905
               +       + VL GD +QL P++ +   +  G+  SL +RL    S           
Sbjct: 663  MEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDP 722

Query: 906  --VVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYS 963
              + +L   YR +  I+ + N+L YEG+L+  +D V       R  +   L  + +    
Sbjct: 723  QFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRE----RFCRWAGLPRQGFPIIF 778

Query: 964  DNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTE-AKLIVFLTSIFVKAGCSPSD 1022
                     E N+P  F        PE+      + VT   KL++  +S   KA  SP  
Sbjct: 779  HGVMGKDEREGNSPSFF-------NPEEA-----ATVTSYLKLLLAPSSKKGKARLSPRS 826

Query: 1023 IGIIAPYRQQLKIINDLLAR---------SIGMVEVNTVDKYQGRDKSIVLVSFVRSNK- 1072
            +G+I+PYR+Q++ I   + +          I  ++V +V+++QG+++S++L+S VRS++ 
Sbjct: 827  VGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQS 886

Query: 1073 ------DGTVGELLKDWRRLNVAITRAKHKLILLG 1101
                  D  +G  LK+ +R NVA+TRAK  LI++G
Sbjct: 887  FVQLDLDFNLG-FLKNPKRFNVAVTRAKALLIIVG 920


>gi|38788372 aquarius [Homo sapiens]
          Length = 1485

 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 97/348 (27%), Positives = 152/348 (43%), Gaps = 60/348 (17%)

Query: 788  IQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKI------ 841
            I+K+   +++F   E+ RS   +S  LL +      I+A TC    H    R        
Sbjct: 1001 IKKIFTQLEEFRASELLRSGLDRSKYLLVK---EAKIIAMTC---THAALKRHDLVKLGF 1054

Query: 842  -FDFCIVDEASQISQPICLGPLF-------FSR--RFVLVGDHQQLPPLVLNREARALG- 890
             +D  +++EA+QI +     PL        FSR  R++++GDH QLPP++ N   +    
Sbjct: 1055 KYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSN 1114

Query: 891  MSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFK 950
            M +SLF R  +     V L  Q R  + + +L N   Y+               NL +  
Sbjct: 1115 MEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYN-WRYK---------------NLGNLP 1158

Query: 951  DVKLELEFYADYSDNPWLMGVFEPNNPVCFLNT-DKVPAPEQVEKGGVSNVTEAKLIVFL 1009
             V+L  EF    + N  L+  F+  N   F    +  P P   +     N+ EA+ +V L
Sbjct: 1159 HVQLLPEFS---TANAGLLYDFQLINVEDFQGVGESEPNPYFYQ-----NLGEAEYVVAL 1210

Query: 1010 TSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMV-------EVNTVDKYQGRDKSI 1062
                   G     I I+  Y  Q  +I D++ R  G         +V TVD++QG+    
Sbjct: 1211 FMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDY 1270

Query: 1063 VLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSL-NCY 1109
            +L+S VR+   G     L+D RRL VA++RA+  L +   V    NC+
Sbjct: 1271 ILLSLVRTRAVGH----LRDVRRLVVAMSRARLGLYIFARVSLFQNCF 1314



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 7/99 (7%)

Query: 730 TLIVGMPGTGKTTTICTLVRILYACGF---SVLLTSYTHSAVDNILLKLAKFKIG---FL 783
           T++VG PGTGKT     ++  +Y   F     L+ ++++ A++ +  K+    I     L
Sbjct: 819 TMVVGPPGTGKTDVAVQIISNIYH-NFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLL 877

Query: 784 RLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQ 822
           RLG  ++     + F+          + + LLEE+   Q
Sbjct: 878 RLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQ 916


>gi|54792138 helicase with zinc finger domain [Homo sapiens]
          Length = 1942

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 107/440 (24%), Positives = 184/440 (41%), Gaps = 82/440 (18%)

Query: 712  LNKPQRQAMKKVL----LSKDYTLIVGMPGTGKTTTICTLVR-ILYACGFSVLLTSYTHS 766
            LN  Q++A+  +     +     LI+G  GTGKT T+   V+ IL      +L+ ++++S
Sbjct: 642  LNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNS 701

Query: 767  AVDNILLKLAKFKIGFLRLGQ--------------IQKVHPAIQQFTEQEICRSKSIKSL 812
            A D   L +  +   ++  G               ++ VHP + Q+    I  + S   +
Sbjct: 702  AAD---LYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCL--ISSAHSTFQM 756

Query: 813  ALLEELYNSQLIVAT--TCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSR---R 867
               E++   +++V T  T   +         F   ++DEA+Q  +   + PL  +    R
Sbjct: 757  PQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTR 816

Query: 868  FVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAV----VQLTVQYRMNSKIMSLS 923
             VL GDH QL P V +  AR   +  SL  RL ++  A     + L   YR +  I++ +
Sbjct: 817  IVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYT 876

Query: 924  NKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNT 983
            ++L YEGKL     + A+        KD    L F+    ++     V E N+   + N 
Sbjct: 877  SELFYEGKLMASGKQPAH--------KDF-YPLTFFTARGED-----VQEKNSTAFYNNA 922

Query: 984  DKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQL-KIINDLLAR 1042
            +     E+VE+         K  V    +          IG++ PY  Q+ +I  +L  +
Sbjct: 923  EVFEVVERVEE------LRRKWPVAWGKL------DDGSIGVVTPYADQVFRIRAELRKK 970

Query: 1043 SIGMVEVNTVDKYQGRDKSIVLVSFVR---------------------SNKDGTVGELLK 1081
             +  V V  V   QG+   ++ +S VR                     S +D   G  L 
Sbjct: 971  RLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYG-FLS 1029

Query: 1082 DWRRLNVAITRAKHKLILLG 1101
            +++ LN AITRA+  + ++G
Sbjct: 1030 NYKLLNTAITRAQSLVAVVG 1049


>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
          Length = 4471

 Score = 34.7 bits (78), Expect = 0.53
 Identities = 64/297 (21%), Positives = 125/297 (42%), Gaps = 39/297 (13%)

Query: 869  VLVGDHQQLPPLVLNRE----ARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSN 924
            V+V D QQ+  ++L  E    A+ L    ++  +L +      QL+ QY  +  + +L +
Sbjct: 1957 VIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLARE-----QLSKQYHYDFGLRALKS 2011

Query: 925  KLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTD 984
             L   G+L+ GS  +   V+ +R  +D+ L  +F   + D P  +G+     P       
Sbjct: 2012 VLVMAGELKRGSSDLREDVVLMRALRDMNLP-KFV--FEDVPLFLGLISDLFPGLDCPRV 2068

Query: 985  KVP----APEQV-EKGG--VSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIIN 1037
            + P    A EQV E+ G  V  +   K++    ++  +         ++ P R    ++ 
Sbjct: 2069 RYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTR-----HTTMVVGPTRGGKSVVI 2123

Query: 1038 DLLARSIGMVEVNTVDKYQGRDKSIVLVSFV----RSNKDGTVGELLKDWRRLNVAITRA 1093
            + L ++   + + T   Y    K++ ++        + +D T G L   +R +N    + 
Sbjct: 2124 NTLCQAQTKLGL-TTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKK 2182

Query: 1094 KHKLILLG------CVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESLCHILGDFQ 1144
            + K IL         V ++N      +LL   N E++ +    + H +L   +GD Q
Sbjct: 2183 ERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRL----QAHCALLFEVGDLQ 2235


>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
          Length = 4624

 Score = 34.7 bits (78), Expect = 0.53
 Identities = 41/148 (27%), Positives = 63/148 (42%), Gaps = 36/148 (24%)

Query: 644  TLFRLDQEE--KNCDIDTPLGNLSKLM--------------ENTFVSKKLRDL----IID 683
            TL++L +E+  K    D  L N+  ++              E+T V + LRD+    +ID
Sbjct: 2136 TLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLID 2195

Query: 684  FREPQFISYLSSVLPHDAKDTV------ACILK-----GLNKPQRQAMKKVLLSKDYTLI 732
              EP F+S +  + P+   D        A I +     GL       +K + L +   + 
Sbjct: 2196 EDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVR 2255

Query: 733  VGM-----PGTGKTTTICTLVRILYACG 755
             GM      G GKTT I TL+R +  CG
Sbjct: 2256 HGMMTLGPSGAGKTTCIHTLMRAMTDCG 2283


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 32.3 bits (72), Expect = 2.6
 Identities = 60/291 (20%), Positives = 114/291 (39%), Gaps = 33/291 (11%)

Query: 264 KLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQ 323
           KLQ+      Q   HLKE     LS ++  +E+E  +    K   D +    S +     
Sbjct: 696 KLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIK---KLEADSLEVKASKEQALQD 752

Query: 324 LSLPSDNSKDNSTCNIEVVKPMDIE-ESIWSPRFGLKGKIDVTVGVKIHRGYKTKYK-IM 381
           L      + D      E+ K +++E E + S R  L+ K +    +K     + + K I+
Sbjct: 753 LQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQIL 812

Query: 382 PLELKTGKESNSIEHR--SQVVLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRE 439
             + +T  +   I+H   +  +  T+   ++    +  L+  L T            K +
Sbjct: 813 KQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTV-----------KDK 861

Query: 440 LLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQM 499
           L K+ + +      + SKS   ++ Q      I++ EKTCK         + +   EQ+ 
Sbjct: 862 LSKVSDSL------KNSKSEFEKENQKGKAA-ILDLEKTCKELKHQLQVQMENTLKEQKE 914

Query: 500 DCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNI 550
                   +   +E+E +   Q  LE  S+   ++  ++  K N+K  Q +
Sbjct: 915 --------LKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQL 957


>gi|70980531 GGA binding partner [Homo sapiens]
          Length = 441

 Score = 31.6 bits (70), Expect = 4.5
 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 13/116 (11%)

Query: 439 ELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCKYC----SQIGNCALYSRA 494
           ELL  ++Q    +     K   ++K + A + Q  E+++  + C     Q    AL S A
Sbjct: 249 ELLNAQHQRLLEMLDT-EKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAA 307

Query: 495 VEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNI 550
              +++  +V   +L  +EEE ++L++ H E   LW         +KD +K  Q I
Sbjct: 308 ---KLEKEAVKDAVLKVVEEERKNLEKAHAEERELW-----KTEHAKDQEKVSQEI 355


>gi|105990532 apolipoprotein B precursor [Homo sapiens]
          Length = 4563

 Score = 31.2 bits (69), Expect = 5.9
 Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 11/62 (17%)

Query: 250  EVFQKAINNSFAPEKLQELA------FQTIQE-IRHLKEM---YRLNLSQDEIKQEVEDY 299
            EVF KAI +    E L+ L       FQ I++ I+ LKEM   Y +N  QDEI     DY
Sbjct: 4282 EVF-KAIQSLKTTEVLRNLQDLLQFIFQLIEDNIKQLKEMKFTYLINYIQDEINTIFSDY 4340

Query: 300  LP 301
            +P
Sbjct: 4341 IP 4342


>gi|239756892 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 576

 Score = 30.8 bits (68), Expect = 7.7
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 6/64 (9%)

Query: 2   KTPCIPSPKQGS-----KGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQ 56
           K  C   P +GS     +GRGQ  A   RG   N+ +R G+  AG   H R G    G  
Sbjct: 143 KGVCPHHPGKGSAGPSRRGRGQR-AKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGET 201

Query: 57  ARAF 60
             ++
Sbjct: 202 GASY 205


>gi|239751388 PREDICTED: hypothetical protein XP_002347834 [Homo
           sapiens]
          Length = 404

 Score = 30.8 bits (68), Expect = 7.7
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 6/64 (9%)

Query: 2   KTPCIPSPKQGS-----KGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQ 56
           K  C   P +GS     +GRGQ  A   RG   N+ +R G+  AG   H R G    G  
Sbjct: 143 KGVCPHHPGKGSAGPSRRGRGQR-AKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGET 201

Query: 57  ARAF 60
             ++
Sbjct: 202 GASY 205


>gi|239745895 PREDICTED: hypothetical protein XP_002343612 [Homo
           sapiens]
          Length = 404

 Score = 30.8 bits (68), Expect = 7.7
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 6/64 (9%)

Query: 2   KTPCIPSPKQGS-----KGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQ 56
           K  C   P +GS     +GRGQ  A   RG   N+ +R G+  AG   H R G    G  
Sbjct: 143 KGVCPHHPGKGSAGPSRRGRGQR-AKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGET 201

Query: 57  ARAF 60
             ++
Sbjct: 202 GASY 205


>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
          Length = 1646

 Score = 30.8 bits (68), Expect = 7.7
 Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 254 KAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLS--QDEIKQEVEDYLPSFCKWAGDFM 311
           + + ++  PEK+    FQ  ++  H ++ Y   L+  Q+EI Q  ++  P      G F+
Sbjct: 293 RGLMDTIVPEKISTSTFQ--RQAEHKRKSYESALASFQEEIAQVGKEMEPLIVDTGGLFL 350

Query: 312 HKNTSTDFPQMQLSLPSDNSKDNSTCNIEVV 342
            K T +D    +L L  +N  +     I+ +
Sbjct: 351 KKLTESDEEMNRLFLKVENDTNLEDYTIQAL 381


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,130,949
Number of Sequences: 37866
Number of extensions: 1855499
Number of successful extensions: 4986
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 4927
Number of HSP's gapped (non-prelim): 44
length of query: 1146
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1033
effective length of database: 13,968,660
effective search space: 14429625780
effective search space used: 14429625780
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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