BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|122937299 DNA replication helicase 2 homolog [Homo sapiens] (1146 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|122937299 DNA replication helicase 2 homolog [Homo sapiens] 2296 0.0 gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens] 175 2e-43 gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens] 171 4e-42 gi|14251207 MOV10-like 1 [Homo sapiens] 112 2e-24 gi|113722133 senataxin [Homo sapiens] 102 2e-21 gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens] 91 8e-18 gi|156105693 PPAR-alpha interacting complex protein 285 isoform ... 90 1e-17 gi|156105695 PPAR-alpha interacting complex protein 285 isoform ... 90 1e-17 gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sap... 86 3e-16 gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapi... 86 3e-16 gi|38788372 aquarius [Homo sapiens] 81 5e-15 gi|54792138 helicase with zinc finger domain [Homo sapiens] 80 1e-14 gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 35 0.53 gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 35 0.53 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 32 2.6 gi|70980531 GGA binding partner [Homo sapiens] 32 4.5 gi|105990532 apolipoprotein B precursor [Homo sapiens] 31 5.9 gi|239756892 PREDICTED: hypothetical protein [Homo sapiens] 31 7.7 gi|239751388 PREDICTED: hypothetical protein XP_002347834 [Homo ... 31 7.7 gi|239745895 PREDICTED: hypothetical protein XP_002343612 [Homo ... 31 7.7 gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 31 7.7 >gi|122937299 DNA replication helicase 2 homolog [Homo sapiens] Length = 1146 Score = 2296 bits (5949), Expect = 0.0 Identities = 1146/1146 (100%), Positives = 1146/1146 (100%) Query: 1 MKTPCIPSPKQGSKGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQARAF 60 MKTPCIPSPKQGSKGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQARAF Sbjct: 1 MKTPCIPSPKQGSKGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQARAF 60 Query: 61 FPFLSFLCYPRFRCLFCLQFAIPASRMEQLNELELLMEKSFWEEAELPAELFQKKVVASF 120 FPFLSFLCYPRFRCLFCLQFAIPASRMEQLNELELLMEKSFWEEAELPAELFQKKVVASF Sbjct: 61 FPFLSFLCYPRFRCLFCLQFAIPASRMEQLNELELLMEKSFWEEAELPAELFQKKVVASF 120 Query: 121 PRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVPVEPG 180 PRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVPVEPG Sbjct: 121 PRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVPVEPG 180 Query: 181 DIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSDPATR 240 DIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSDPATR Sbjct: 181 DIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSDPATR 240 Query: 241 QMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYL 300 QMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYL Sbjct: 241 QMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYL 300 Query: 301 PSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKG 360 PSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKG Sbjct: 301 PSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKG 360 Query: 361 KIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEAGLLL 420 KIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEAGLLL Sbjct: 361 KIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEAGLLL 420 Query: 421 YLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCK 480 YLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCK Sbjct: 421 YLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCK 480 Query: 481 YCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQS 540 YCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQS Sbjct: 481 YCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQS 540 Query: 541 KDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMA 600 KDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMA Sbjct: 541 KDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMA 600 Query: 601 GDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTP 660 GDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTP Sbjct: 601 GDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTP 660 Query: 661 LGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAM 720 LGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAM Sbjct: 661 LGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAM 720 Query: 721 KKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKI 780 KKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKI Sbjct: 721 KKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKI 780 Query: 781 GFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRK 840 GFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRK Sbjct: 781 GFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRK 840 Query: 841 IFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLE 900 IFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLE Sbjct: 841 IFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLE 900 Query: 901 QNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYA 960 QNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYA Sbjct: 901 QNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYA 960 Query: 961 DYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSP 1020 DYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSP Sbjct: 961 DYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSP 1020 Query: 1021 SDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELL 1080 SDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELL Sbjct: 1021 SDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELL 1080 Query: 1081 KDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESLCHIL 1140 KDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESLCHIL Sbjct: 1081 KDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESLCHIL 1140 Query: 1141 GDFQRE 1146 GDFQRE Sbjct: 1141 GDFQRE 1146 >gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens] Length = 1118 Score = 175 bits (444), Expect = 2e-43 Identities = 137/465 (29%), Positives = 231/465 (49%), Gaps = 74/465 (15%) Query: 709 LKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFS-VLLTSYTHSA 767 L LN Q A+K VL + +LI G PGTGKT T T+V L G VL+ + ++ A Sbjct: 468 LPDLNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIA 526 Query: 768 VDNILLKLAKFKIGFLRL------------------------------GQIQKVHPAIQQ 797 VD + K+ + + +RL ++Q++ + Sbjct: 527 VDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGE 586 Query: 798 FTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPI 857 + + R +++K A E L N+ ++ TC+G P ++ F ++DE++Q ++P Sbjct: 587 LSSADEKRYRALKRTAERELLMNAD-VICCTCVGAGDPRLAKMQFRSILIDESTQATEPE 645 Query: 858 CLGPLFF-SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMN 916 C+ P+ +++ +LVGDH QL P+V+ ++A G+S+SLF+RL ++L VQYRM+ Sbjct: 646 CMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMH 705 Query: 917 SKIMSLSNKLTYEGKLECG---SDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFE 973 + + + + YEG L+ G +D+V D W + Sbjct: 706 PALSAFPSNIFYEGSLQNGVTAADRVKKGF--------------------DFQWP----Q 741 Query: 974 PNNPVCFLNTDKVPAPEQVEKGGVS--NVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYR- 1030 P+ P+ F T E++ G S N TEA + +T+ +KAG P IGII PY Sbjct: 742 PDKPMFFYVTQ---GQEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEG 798 Query: 1031 ------QQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWR 1084 Q ++ L + VE+ +VD +QGR+K +++S VR+N+ +G L D R Sbjct: 799 QRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIG-FLNDPR 857 Query: 1085 RLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLP 1129 RLNVA+TRA++ +I++G +L+ P LLN+ +K++++ P Sbjct: 858 RLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGP 902 >gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens] Length = 993 Score = 171 bits (433), Expect = 4e-42 Identities = 172/651 (26%), Positives = 288/651 (44%), Gaps = 102/651 (15%) Query: 532 LMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKH- 590 L L +++ ++ + +NI L E++ G C+ L ++ + G+ L F+ + Sbjct: 17 LELERDAEVEERRSWQENISL---KELQSRGVCLLKL-QVSSQRTGLYGRLLVTFEPRRY 72 Query: 591 ---GAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFR 647 A+P + +GD V + L+ G + + +VT D ES F+ Sbjct: 73 GSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFD-------ESHDFQ 125 Query: 648 LDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFRE------PQFISYL---SSVLP 698 L + +N L KL N ++L+ +I ++ I L S+ P Sbjct: 126 LSLDRENSY------RLLKLA-NDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSP 178 Query: 699 HDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSV 758 + L+ Q++A+ L K+ +I G PGTGKTTT+ ++ G V Sbjct: 179 ASEIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKV 238 Query: 759 LLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQ--------------------- 797 L + ++ AVDN++ +LA K LRLG ++ +IQQ Sbjct: 239 LCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRK 298 Query: 798 -----FTEQEICRSKSIKS------------------LALLEELYNSQLIVAT-TCMGIN 833 F + + + K KS A+LE L ++ +++AT T + Sbjct: 299 DIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASAD 358 Query: 834 HPI--FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGM 891 P+ FD ++DE +Q + C PL +R+ +L GDH+QLPP ++ +A G+ Sbjct: 359 GPLKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGL 418 Query: 892 SESLFKRLEQNKSAVV--QLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHF 949 S SL +RL + A V LTVQYRM+ IM ++ Y G+L S RH Sbjct: 419 SLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVA-------RHL 471 Query: 950 KDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVS--NVTEAKLIV 1007 D P + E P+ ++T E E+ S N E +L+ Sbjct: 472 ------------LRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVS 519 Query: 1008 FLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSF 1067 V AG DI +++PY Q+ ++ L +E+ +VD +QGR+K V++SF Sbjct: 520 LHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSF 579 Query: 1068 VRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNH 1118 VRSN+ G VG L +D RR+NVA+TRA+ + ++ ++N + L+ L+ + Sbjct: 580 VRSNRKGEVGFLAED-RRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEY 629 >gi|14251207 MOV10-like 1 [Homo sapiens] Length = 1211 Score = 112 bits (281), Expect = 2e-24 Identities = 122/435 (28%), Positives = 203/435 (46%), Gaps = 77/435 (17%) Query: 712 LNKPQRQAMKKVLLSKDYTL---IVGMPGTGKTTTICTLV-RILYACGFS-VLLTSYTHS 766 LN+ Q+ A+K++L L + G PGTGKT TI V ++ +A S +L+ + ++S Sbjct: 745 LNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRILVCAPSNS 804 Query: 767 AVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALL------EELYN 820 A D + L+L + K+ L+ + +V+ CR + I A+ E+++ Sbjct: 805 AADLVCLRLHESKV--LQPATMVRVNAT---------CRFEEIVIDAVKPYCRDGEDIWK 853 Query: 821 SQL--IVATTCM--GINHPIFSRK-IFDFCIVDEASQISQPICLGPLFF----SRRFVLV 871 + I+ TTC G+ + I R F VDEA Q S+P CL PL S + VL Sbjct: 854 ASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLA 913 Query: 872 GDHQQLPPLVLNREARALGMSESLFKRL-----------------EQNKSAVVQLTVQYR 914 GD QL P++ +R A A G++ S +RL N V +L YR Sbjct: 914 GDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYR 973 Query: 915 MNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFE 973 + ++ L ++L Y +LE C V +++ L F+ E Sbjct: 974 SHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSE-----ARE 1028 Query: 974 PNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQL 1033 +P F + V + L + + + S SDIG+I PYR+Q+ Sbjct: 1029 GKSPSWFNPAEAV---------------QVLRYCCLLAHSISSQVSASDIGVITPYRKQV 1073 Query: 1034 KIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGE-----LLKDWRRL 1086 + I +L R++ + ++V +V+++QG++ ++++S VRSN+D + L + +R Sbjct: 1074 EKIR-ILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRF 1132 Query: 1087 NVAITRAKHKLILLG 1101 NVAITR K LI+LG Sbjct: 1133 NVAITRPKALLIVLG 1147 >gi|113722133 senataxin [Homo sapiens] Length = 2677 Score = 102 bits (255), Expect = 2e-21 Identities = 97/322 (30%), Positives = 147/322 (45%), Gaps = 62/322 (19%) Query: 803 ICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPL 862 IC + S LLE + Q V +C+ IVDEA Q + L PL Sbjct: 2151 ICCTLSTSGGLLLESAFRGQGGVPFSCV---------------IVDEAGQSCEIETLTPL 2195 Query: 863 FFS-RRFVLVGDHQQLPPLVLNREARALGMSESLFKR----LEQN-------KSAVVQLT 910 + +LVGD +QLPP V++ +A+ G +S+ R LE+N + ++QLT Sbjct: 2196 IHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLT 2255 Query: 911 VQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMG 970 VQYRM+ I + Y L+ A + +D+ P+L Sbjct: 2256 VQYRMHPDICLFPSNYVYNRNLKTNRQTEA---------------IRCSSDWPFQPYL-- 2298 Query: 971 VFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFV--KAGCSPSDIGIIAP 1028 VF+ + E+ + NV E KL++ + + + S +IGII Sbjct: 2299 VFDVGD-----------GSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITH 2347 Query: 1029 YRQQLKIINDLLARSI---GMVEVNTVDKYQGRDKSIVLVSFVRSNK-DGTVGELLKDWR 1084 Y+ Q +I L + G EV+TVD +QGR K V+V+ VR+N G++G L + Sbjct: 2348 YKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG-FLASLQ 2406 Query: 1085 RLNVAITRAKHKLILLGCVPSL 1106 RLNV ITRAK+ L +LG + +L Sbjct: 2407 RLNVTITRAKYSLFILGHLRTL 2428 >gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens] Length = 1918 Score = 90.5 bits (223), Expect = 8e-18 Identities = 94/340 (27%), Positives = 155/340 (45%), Gaps = 41/340 (12%) Query: 795 IQQFTEQEICRSKSIKSLALLEELY---NSQLIVATTCMGINHPIFSRKIFD-FCIVDEA 850 I + Q ++ + L L E+L+ ++Q++ TT + +K+ IV+EA Sbjct: 949 ILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEA 1008 Query: 851 SQISQPICLGPLFFS-RRFVLVGDHQQLPPLVLNRE-ARALGMSESLFKRLEQNKSAVVQ 908 +++ + + L + + +L+GDHQQL P + A+ + SLF+RL + V+ Sbjct: 1009 AEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVR 1068 Query: 909 LTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWL 968 L Q+RM +I L Y+ S V+ K V L F+ +++ Sbjct: 1069 LNYQHRMCPEIARLLTPHIYQDLENHPS------VLKYEKIKGVSSNL-FFVEHN----- 1116 Query: 969 MGVFEPNNPVCFLNTDKVPAPEQVEKGGVS--NVTEAKLIVFLTSIFVKAGCSPSDIGII 1026 PEQ + G S N EA +V L F+ PS I I+ Sbjct: 1117 -------------------FPEQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITIL 1157 Query: 1027 APYRQQLKIINDLL-ARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRR 1085 Y QL + L+ A++ V V+ VDKYQG + I+L+S VRSN++G VG L+ R Sbjct: 1158 TTYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSNQEGKVG-FLQISNR 1216 Query: 1086 LNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLI 1125 + VA++RAK + +G + L P K+++ L I Sbjct: 1217 ICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENNQI 1256 Score = 32.0 bits (71), Expect = 3.5 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 12/109 (11%) Query: 712 LNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYA---------CGFSVLLTS 762 L+ Q +A++ L+++ +I G PGTGKT +V+ L F +L+ Sbjct: 598 LDDSQMEALQ-FALTRELAIIQGPPGTGKTYVGLKIVQALLTNESVWQISLQKFPILVVC 656 Query: 763 YTHSAVDNILLKLAKF-KIGFLRLGQIQKVHPAIQQFTEQEICRSKSIK 810 YT+ A+D L + K +R+G + ++QFT +E+ + + Sbjct: 657 YTNHALDQFLEGIYNCQKTSIVRVGG-RSNSEILKQFTLRELRNKREFR 704 >gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1 [Homo sapiens] Length = 2649 Score = 90.1 bits (222), Expect = 1e-17 Identities = 93/348 (26%), Positives = 155/348 (44%), Gaps = 43/348 (12%) Query: 798 FTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDF--CIVDEASQISQ 855 F+ +++ K + A EL ++I+ T + S KI D +VDEA ++ Sbjct: 2311 FSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASA---SLKILDVRQILVDEAGMATE 2367 Query: 856 PICLGPLFF---SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQ 912 P L PL + + VL+GDH+QL P+V N + LG+ SLF+R ++ L Q Sbjct: 2368 PETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAH---MLDTQ 2424 Query: 913 YRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVF 972 YRM+ I + + Y+ KL+ LR V +A P + G Sbjct: 2425 YRMHEGICAFPSVAFYKSKLKTWQ--------GLRRPPSVL----GHAGKESCPVIFGHV 2472 Query: 973 EPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLT-SIFVKAGCSPSDIGIIAPYRQ 1031 + + ++TD + + +N+ E +V +T + + P DI ++ PY Sbjct: 2473 QGHERSLLVSTD------EGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNA 2526 Query: 1032 QLKIINDLLAR-SIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGEL-LKDW------ 1083 Q I+ L R I V V+++ K QG + VLVS VR+ + + K W Sbjct: 2527 QASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLG 2586 Query: 1084 -----RRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLII 1126 ++NVA+TRA+ L L+G L C P LL+ +++ ++ Sbjct: 2587 FVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2634 Score = 55.8 bits (133), Expect = 2e-07 Identities = 88/413 (21%), Positives = 163/413 (39%), Gaps = 54/413 (13%) Query: 731 LIVGMPGTGKTTTICTL-VRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGF------- 782 LI G GTGKT T+ + ++ VL+ ++T+SA D + + + Sbjct: 541 LIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATP 600 Query: 783 LRLGQIQKVHPAIQQFTEQEICRSKSIKSLA--LLEELYNSQLIVATTCMG--INHPIFS 838 LR+ + T Q C + ++ EL +++V TT + P+ Sbjct: 601 LRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVPV-- 658 Query: 839 RKIFDFCIVDEASQISQPICLGPLFFSR---RFVLVGDHQQLPPLVLNREARALGMSESL 895 F ++DEA+Q+ + L PL ++ R VL GDH Q+ P + + ARA +L Sbjct: 659 -GFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTL 716 Query: 896 FKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLE 955 R L + Y+ + ++ ++L + C +A+++ + Sbjct: 717 LHR----------LFLCYQQETHEVARQSRLVFHENYRC-----TDAIVSF-------IS 754 Query: 956 LEFYADYSDNPWLMGVFEP---NNPVCFLNTDKVPAPEQ-----VEKGGVSNVTEAKLIV 1007 FY + G P + P+ F + P + + ++ V E Sbjct: 755 RHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEA 814 Query: 1008 FLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSF 1067 + T G I +++ Q + +L R +G V V + + GR +V++S Sbjct: 815 YNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLST 874 Query: 1068 VRS-----NKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKL 1115 V + + E D R LN +TRA+ +L+++G +L + KL Sbjct: 875 VHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKL 927 >gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2 [Homo sapiens] Length = 2080 Score = 90.1 bits (222), Expect = 1e-17 Identities = 93/348 (26%), Positives = 155/348 (44%), Gaps = 43/348 (12%) Query: 798 FTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDF--CIVDEASQISQ 855 F+ +++ K + A EL ++I+ T + S KI D +VDEA ++ Sbjct: 1742 FSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASA---SLKILDVRQILVDEAGMATE 1798 Query: 856 PICLGPLFF---SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQ 912 P L PL + + VL+GDH+QL P+V N + LG+ SLF+R ++ L Q Sbjct: 1799 PETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAH---MLDTQ 1855 Query: 913 YRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVF 972 YRM+ I + + Y+ KL+ LR V +A P + G Sbjct: 1856 YRMHEGICAFPSVAFYKSKLKTWQ--------GLRRPPSVL----GHAGKESCPVIFGHV 1903 Query: 973 EPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLT-SIFVKAGCSPSDIGIIAPYRQ 1031 + + ++TD + + +N+ E +V +T + + P DI ++ PY Sbjct: 1904 QGHERSLLVSTD------EGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNA 1957 Query: 1032 QLKIINDLLAR-SIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGEL-LKDW------ 1083 Q I+ L R I V V+++ K QG + VLVS VR+ + + K W Sbjct: 1958 QASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLG 2017 Query: 1084 -----RRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLII 1126 ++NVA+TRA+ L L+G L C P LL+ +++ ++ Sbjct: 2018 FVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2065 Score = 50.4 bits (119), Expect = 9e-06 Identities = 68/317 (21%), Positives = 127/317 (40%), Gaps = 44/317 (13%) Query: 817 ELYNSQLIVATTCMG--INHPIFSRKIFDFCIVDEASQISQPICLGPLFFSR---RFVLV 871 EL +++V TT + P+ F ++DEA+Q+ + L PL ++ R VL Sbjct: 68 ELARHRVVVTTTSQARELRVPV---GFFSHILIDEAAQMLECEALTPLAYASHGTRLVLA 124 Query: 872 GDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGK 931 GDH Q+ P + + ARA +L R L + Y+ + ++ ++L + Sbjct: 125 GDHMQVTPRLFS-VARARAAEHTLLHR----------LFLCYQQETHEVARQSRLVFHEN 173 Query: 932 LECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEP---NNPVCFLNTDKVPA 988 C +A+++ + FY + G P + P+ F + P Sbjct: 174 YRC-----TDAIVSF-------ISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPD 221 Query: 989 PEQ-----VEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARS 1043 + + ++ V E + T G I +++ Q + +L R Sbjct: 222 RDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRD 281 Query: 1044 IGMVEVNTVDKYQGRDKSIVLVSFVRS-----NKDGTVGELLKDWRRLNVAITRAKHKLI 1098 +G V V + + GR +V++S V + + E D R LN +TRA+ +L+ Sbjct: 282 LGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLV 341 Query: 1099 LLGCVPSLNCYPPLEKL 1115 ++G +L + KL Sbjct: 342 VVGDAVALCSFGACGKL 358 >gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens] Length = 1003 Score = 85.5 bits (210), Expect = 3e-16 Identities = 111/455 (24%), Positives = 196/455 (43%), Gaps = 66/455 (14%) Query: 696 VLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT---LIVGMPGTGKTTTICTLVR--I 750 +LP D K + N Q QAM+ ++ +I G PGTGKT T+ ++ + Sbjct: 483 LLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVV 542 Query: 751 LYACGFSVLLTSYTHSAVDNILLKL-AKFKIGFLRL----GQIQKVHPAIQQFTEQEICR 805 + +L + ++S D + +L RL I+ V I+ + + Sbjct: 543 KHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKK 602 Query: 806 SKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQP---ICLGPL 862 + + + Y + T + F F +DEA +P + + L Sbjct: 603 GEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGL 662 Query: 863 FFSR-------RFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSA---------- 905 + + VL GD +QL P++ + + G+ SL +RL S Sbjct: 663 MEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDP 722 Query: 906 --VVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYS 963 + +L YR + I+ + N+L YEG+L+ +D V R + L + + Sbjct: 723 QFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRE----RFCRWAGLPRQGFPIIF 778 Query: 964 DNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTE-AKLIVFLTSIFVKAGCSPSD 1022 E N+P F PE+ + VT KL++ +S KA SP Sbjct: 779 HGVMGKDEREGNSPSFF-------NPEEA-----ATVTSYLKLLLAPSSKKGKARLSPRS 826 Query: 1023 IGIIAPYRQQLKIINDLLAR---------SIGMVEVNTVDKYQGRDKSIVLVSFVRSNK- 1072 +G+I+PYR+Q++ I + + I ++V +V+++QG+++S++L+S VRS++ Sbjct: 827 VGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQS 886 Query: 1073 ------DGTVGELLKDWRRLNVAITRAKHKLILLG 1101 D +G LK+ +R NVA+TRAK LI++G Sbjct: 887 FVQLDLDFNLG-FLKNPKRFNVAVTRAKALLIIVG 920 >gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens] Length = 1003 Score = 85.5 bits (210), Expect = 3e-16 Identities = 111/455 (24%), Positives = 196/455 (43%), Gaps = 66/455 (14%) Query: 696 VLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT---LIVGMPGTGKTTTICTLVR--I 750 +LP D K + N Q QAM+ ++ +I G PGTGKT T+ ++ + Sbjct: 483 LLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVV 542 Query: 751 LYACGFSVLLTSYTHSAVDNILLKL-AKFKIGFLRL----GQIQKVHPAIQQFTEQEICR 805 + +L + ++S D + +L RL I+ V I+ + + Sbjct: 543 KHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKK 602 Query: 806 SKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQP---ICLGPL 862 + + + Y + T + F F +DEA +P + + L Sbjct: 603 GEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGL 662 Query: 863 FFSR-------RFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSA---------- 905 + + VL GD +QL P++ + + G+ SL +RL S Sbjct: 663 MEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDP 722 Query: 906 --VVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYS 963 + +L YR + I+ + N+L YEG+L+ +D V R + L + + Sbjct: 723 QFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRE----RFCRWAGLPRQGFPIIF 778 Query: 964 DNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTE-AKLIVFLTSIFVKAGCSPSD 1022 E N+P F PE+ + VT KL++ +S KA SP Sbjct: 779 HGVMGKDEREGNSPSFF-------NPEEA-----ATVTSYLKLLLAPSSKKGKARLSPRS 826 Query: 1023 IGIIAPYRQQLKIINDLLAR---------SIGMVEVNTVDKYQGRDKSIVLVSFVRSNK- 1072 +G+I+PYR+Q++ I + + I ++V +V+++QG+++S++L+S VRS++ Sbjct: 827 VGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQS 886 Query: 1073 ------DGTVGELLKDWRRLNVAITRAKHKLILLG 1101 D +G LK+ +R NVA+TRAK LI++G Sbjct: 887 FVQLDLDFNLG-FLKNPKRFNVAVTRAKALLIIVG 920 >gi|38788372 aquarius [Homo sapiens] Length = 1485 Score = 81.3 bits (199), Expect = 5e-15 Identities = 97/348 (27%), Positives = 152/348 (43%), Gaps = 60/348 (17%) Query: 788 IQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKI------ 841 I+K+ +++F E+ RS +S LL + I+A TC H R Sbjct: 1001 IKKIFTQLEEFRASELLRSGLDRSKYLLVK---EAKIIAMTC---THAALKRHDLVKLGF 1054 Query: 842 -FDFCIVDEASQISQPICLGPLF-------FSR--RFVLVGDHQQLPPLVLNREARALG- 890 +D +++EA+QI + PL FSR R++++GDH QLPP++ N + Sbjct: 1055 KYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSN 1114 Query: 891 MSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFK 950 M +SLF R + V L Q R + + +L N Y+ NL + Sbjct: 1115 MEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYN-WRYK---------------NLGNLP 1158 Query: 951 DVKLELEFYADYSDNPWLMGVFEPNNPVCFLNT-DKVPAPEQVEKGGVSNVTEAKLIVFL 1009 V+L EF + N L+ F+ N F + P P + N+ EA+ +V L Sbjct: 1159 HVQLLPEFS---TANAGLLYDFQLINVEDFQGVGESEPNPYFYQ-----NLGEAEYVVAL 1210 Query: 1010 TSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMV-------EVNTVDKYQGRDKSI 1062 G I I+ Y Q +I D++ R G +V TVD++QG+ Sbjct: 1211 FMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDY 1270 Query: 1063 VLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSL-NCY 1109 +L+S VR+ G L+D RRL VA++RA+ L + V NC+ Sbjct: 1271 ILLSLVRTRAVGH----LRDVRRLVVAMSRARLGLYIFARVSLFQNCF 1314 Score = 31.2 bits (69), Expect = 5.9 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 7/99 (7%) Query: 730 TLIVGMPGTGKTTTICTLVRILYACGF---SVLLTSYTHSAVDNILLKLAKFKIG---FL 783 T++VG PGTGKT ++ +Y F L+ ++++ A++ + K+ I L Sbjct: 819 TMVVGPPGTGKTDVAVQIISNIYH-NFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLL 877 Query: 784 RLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQ 822 RLG ++ + F+ + + LLEE+ Q Sbjct: 878 RLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQ 916 >gi|54792138 helicase with zinc finger domain [Homo sapiens] Length = 1942 Score = 80.1 bits (196), Expect = 1e-14 Identities = 107/440 (24%), Positives = 184/440 (41%), Gaps = 82/440 (18%) Query: 712 LNKPQRQAMKKVL----LSKDYTLIVGMPGTGKTTTICTLVR-ILYACGFSVLLTSYTHS 766 LN Q++A+ + + LI+G GTGKT T+ V+ IL +L+ ++++S Sbjct: 642 LNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNS 701 Query: 767 AVDNILLKLAKFKIGFLRLGQ--------------IQKVHPAIQQFTEQEICRSKSIKSL 812 A D L + + ++ G ++ VHP + Q+ I + S + Sbjct: 702 AAD---LYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCL--ISSAHSTFQM 756 Query: 813 ALLEELYNSQLIVAT--TCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSR---R 867 E++ +++V T T + F ++DEA+Q + + PL + R Sbjct: 757 PQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTR 816 Query: 868 FVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAV----VQLTVQYRMNSKIMSLS 923 VL GDH QL P V + AR + SL RL ++ A + L YR + I++ + Sbjct: 817 IVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYT 876 Query: 924 NKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNT 983 ++L YEGKL + A+ KD L F+ ++ V E N+ + N Sbjct: 877 SELFYEGKLMASGKQPAH--------KDF-YPLTFFTARGED-----VQEKNSTAFYNNA 922 Query: 984 DKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQL-KIINDLLAR 1042 + E+VE+ K V + IG++ PY Q+ +I +L + Sbjct: 923 EVFEVVERVEE------LRRKWPVAWGKL------DDGSIGVVTPYADQVFRIRAELRKK 970 Query: 1043 SIGMVEVNTVDKYQGRDKSIVLVSFVR---------------------SNKDGTVGELLK 1081 + V V V QG+ ++ +S VR S +D G L Sbjct: 971 RLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYG-FLS 1029 Query: 1082 DWRRLNVAITRAKHKLILLG 1101 +++ LN AITRA+ + ++G Sbjct: 1030 NYKLLNTAITRAQSLVAVVG 1049 >gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] Length = 4471 Score = 34.7 bits (78), Expect = 0.53 Identities = 64/297 (21%), Positives = 125/297 (42%), Gaps = 39/297 (13%) Query: 869 VLVGDHQQLPPLVLNRE----ARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSN 924 V+V D QQ+ ++L E A+ L ++ +L + QL+ QY + + +L + Sbjct: 1957 VIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLARE-----QLSKQYHYDFGLRALKS 2011 Query: 925 KLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTD 984 L G+L+ GS + V+ +R +D+ L +F + D P +G+ P Sbjct: 2012 VLVMAGELKRGSSDLREDVVLMRALRDMNLP-KFV--FEDVPLFLGLISDLFPGLDCPRV 2068 Query: 985 KVP----APEQV-EKGG--VSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIIN 1037 + P A EQV E+ G V + K++ ++ + ++ P R ++ Sbjct: 2069 RYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTR-----HTTMVVGPTRGGKSVVI 2123 Query: 1038 DLLARSIGMVEVNTVDKYQGRDKSIVLVSFV----RSNKDGTVGELLKDWRRLNVAITRA 1093 + L ++ + + T Y K++ ++ + +D T G L +R +N + Sbjct: 2124 NTLCQAQTKLGL-TTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKK 2182 Query: 1094 KHKLILLG------CVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESLCHILGDFQ 1144 + K IL V ++N +LL N E++ + + H +L +GD Q Sbjct: 2183 ERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRL----QAHCALLFEVGDLQ 2235 >gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] Length = 4624 Score = 34.7 bits (78), Expect = 0.53 Identities = 41/148 (27%), Positives = 63/148 (42%), Gaps = 36/148 (24%) Query: 644 TLFRLDQEE--KNCDIDTPLGNLSKLM--------------ENTFVSKKLRDL----IID 683 TL++L +E+ K D L N+ ++ E+T V + LRD+ +ID Sbjct: 2136 TLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLID 2195 Query: 684 FREPQFISYLSSVLPHDAKDTV------ACILK-----GLNKPQRQAMKKVLLSKDYTLI 732 EP F+S + + P+ D A I + GL +K + L + + Sbjct: 2196 EDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVR 2255 Query: 733 VGM-----PGTGKTTTICTLVRILYACG 755 GM G GKTT I TL+R + CG Sbjct: 2256 HGMMTLGPSGAGKTTCIHTLMRAMTDCG 2283 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 32.3 bits (72), Expect = 2.6 Identities = 60/291 (20%), Positives = 114/291 (39%), Gaps = 33/291 (11%) Query: 264 KLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQ 323 KLQ+ Q HLKE LS ++ +E+E + K D + S + Sbjct: 696 KLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIK---KLEADSLEVKASKEQALQD 752 Query: 324 LSLPSDNSKDNSTCNIEVVKPMDIE-ESIWSPRFGLKGKIDVTVGVKIHRGYKTKYK-IM 381 L + D E+ K +++E E + S R L+ K + +K + + K I+ Sbjct: 753 LQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQIL 812 Query: 382 PLELKTGKESNSIEHR--SQVVLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRE 439 + +T + I+H + + T+ ++ + L+ L T K + Sbjct: 813 KQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTV-----------KDK 861 Query: 440 LLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQM 499 L K+ + + + SKS ++ Q I++ EKTCK + + EQ+ Sbjct: 862 LSKVSDSL------KNSKSEFEKENQKGKAA-ILDLEKTCKELKHQLQVQMENTLKEQKE 914 Query: 500 DCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNI 550 + +E+E + Q LE S+ ++ ++ K N+K Q + Sbjct: 915 --------LKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQL 957 >gi|70980531 GGA binding partner [Homo sapiens] Length = 441 Score = 31.6 bits (70), Expect = 4.5 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 13/116 (11%) Query: 439 ELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEEKTCKYC----SQIGNCALYSRA 494 ELL ++Q + K ++K + A + Q E+++ + C Q AL S A Sbjct: 249 ELLNAQHQRLLEMLDT-EKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAA 307 Query: 495 VEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNI 550 +++ +V +L +EEE ++L++ H E LW +KD +K Q I Sbjct: 308 ---KLEKEAVKDAVLKVVEEERKNLEKAHAEERELW-----KTEHAKDQEKVSQEI 355 >gi|105990532 apolipoprotein B precursor [Homo sapiens] Length = 4563 Score = 31.2 bits (69), Expect = 5.9 Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 11/62 (17%) Query: 250 EVFQKAINNSFAPEKLQELA------FQTIQE-IRHLKEM---YRLNLSQDEIKQEVEDY 299 EVF KAI + E L+ L FQ I++ I+ LKEM Y +N QDEI DY Sbjct: 4282 EVF-KAIQSLKTTEVLRNLQDLLQFIFQLIEDNIKQLKEMKFTYLINYIQDEINTIFSDY 4340 Query: 300 LP 301 +P Sbjct: 4341 IP 4342 >gi|239756892 PREDICTED: hypothetical protein [Homo sapiens] Length = 576 Score = 30.8 bits (68), Expect = 7.7 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 6/64 (9%) Query: 2 KTPCIPSPKQGS-----KGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQ 56 K C P +GS +GRGQ A RG N+ +R G+ AG H R G G Sbjct: 143 KGVCPHHPGKGSAGPSRRGRGQR-AKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGET 201 Query: 57 ARAF 60 ++ Sbjct: 202 GASY 205 >gi|239751388 PREDICTED: hypothetical protein XP_002347834 [Homo sapiens] Length = 404 Score = 30.8 bits (68), Expect = 7.7 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 6/64 (9%) Query: 2 KTPCIPSPKQGS-----KGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQ 56 K C P +GS +GRGQ A RG N+ +R G+ AG H R G G Sbjct: 143 KGVCPHHPGKGSAGPSRRGRGQR-AKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGET 201 Query: 57 ARAF 60 ++ Sbjct: 202 GASY 205 >gi|239745895 PREDICTED: hypothetical protein XP_002343612 [Homo sapiens] Length = 404 Score = 30.8 bits (68), Expect = 7.7 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 6/64 (9%) Query: 2 KTPCIPSPKQGS-----KGRGQSPAAQVRGPTWNAPAREGRPGAGHLGHLRVGACARGAQ 56 K C P +GS +GRGQ A RG N+ +R G+ AG H R G G Sbjct: 143 KGVCPHHPGKGSAGPSRRGRGQR-AKGFRGSEMNSESRRGQTAAGREKHPRAGCSGEGET 201 Query: 57 ARAF 60 ++ Sbjct: 202 GASY 205 >gi|55741661 hypothetical protein LOC57653 [Homo sapiens] Length = 1646 Score = 30.8 bits (68), Expect = 7.7 Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 4/91 (4%) Query: 254 KAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLS--QDEIKQEVEDYLPSFCKWAGDFM 311 + + ++ PEK+ FQ ++ H ++ Y L+ Q+EI Q ++ P G F+ Sbjct: 293 RGLMDTIVPEKISTSTFQ--RQAEHKRKSYESALASFQEEIAQVGKEMEPLIVDTGGLFL 350 Query: 312 HKNTSTDFPQMQLSLPSDNSKDNSTCNIEVV 342 K T +D +L L +N + I+ + Sbjct: 351 KKLTESDEEMNRLFLKVENDTNLEDYTIQAL 381 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.136 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 42,130,949 Number of Sequences: 37866 Number of extensions: 1855499 Number of successful extensions: 4986 Number of sequences better than 10.0: 21 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 4927 Number of HSP's gapped (non-prelim): 44 length of query: 1146 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1033 effective length of database: 13,968,660 effective search space: 14429625780 effective search space used: 14429625780 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.