Guide to the Human Genome
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Name: FTO Sequence: fasta or formatted (505aa) NCBI GI: 122937263
Description:

fat mass and obesity associated

Not currently referenced in the text

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.1         36           3
 C cysteine            2.8         14           1
 D aspartate           6.5         33           2
 E glutamate           9.9         50           3
 F phenylalanine       3.2         16           1
 G glycine             4.4         22           1
 H histidine           3.0         15           2
 I isoleucine          3.8         19           1
 K lysine              5.7         29           2
 L leucine            11.1         56           2
 M methionine          2.2         11           1
 N asparagine          3.4         17           1
 P proline             5.3         27           1
 Q glutamine           5.0         25           2
 R arginine            5.7         29           2
 S serine              5.1         26           2
 T threonine           4.8         24           1
 V valine              5.3         27           1
 W tryptophan          2.6         13           2
 Y tyrosine            3.2         16           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   fat mass and obesity associated 
ZRSR2                 0.008   U2 small nuclear RNA auxiliary factor 1-like 2 
EIF4A2                0.008   eukaryotic translation initiation factor 4A2 
DNAH1                 0.008   dynein, axonemal, heavy chain 1 
ALKBH2                0.006   AlkB homolog 2 
ALKBH2                0.006   AlkB homolog 2 
ALKBH2                0.006   AlkB homolog 2 
STT3B                 0.006   source of immunodominant MHC-associated peptides [Ho...
NBEAL2                0.005   neurobeachin-like 2 
MINK1                 0.005   misshapen/NIK-related kinase isoform 4 
MINK1                 0.005   misshapen/NIK-related kinase isoform 2 
MINK1                 0.005   misshapen/NIK-related kinase isoform 3 
MINK1                 0.005   misshapen/NIK-related kinase isoform 1 
MAP3K4                0.005   mitogen-activated protein kinase kinase kinase 4 iso...
MAP3K4                0.005   mitogen-activated protein kinase kinase kinase 4 iso...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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