Search of human proteins with 29171682

Search of human proteins with 29171682

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29171682 interleukin 9 receptor precursor [Homo sapiens]
         (521 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29171682 interleukin 9 receptor precursor [Homo sapiens]          1105   0.0  
gi|4503591 erythropoietin receptor precursor [Homo sapiens]            74   2e-13
gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]        72   2e-12
gi|31083174 interleukin 21 receptor precursor [Homo sapiens]           69   1e-11
gi|11141869 interleukin 21 receptor precursor [Homo sapiens]           69   1e-11
gi|31083180 interleukin 21 receptor precursor [Homo sapiens]           69   1e-11
gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo sapi...    48   2e-05
gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo sapi...    48   2e-05
gi|4559408 colony stimulating factor 2 receptor, beta precursor ...    47   6e-05
gi|51093381 leptin receptor isoform 3 [Homo sapiens]                   37   0.034
gi|51093379 leptin receptor isoform 2 [Homo sapiens]                   37   0.034
gi|40254464 leptin receptor isoform 1 [Homo sapiens]                   37   0.034
gi|28610151 interleukin 7 receptor precursor [Homo sapiens]            34   0.28 
gi|4557040 oncostatin M receptor [Homo sapiens]                        33   0.48 
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]              33   0.48 
gi|13194201 reticulon 4 receptor precursor [Homo sapiens]              33   0.63 
gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo ...    33   0.63 
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         33   0.83 
gi|24497517 homeobox A5 [Homo sapiens]                                 32   1.1  
gi|40807477 retinoic acid induced 1 [Homo sapiens]                     32   1.4  
gi|61966721 Tctex1 domain containing 4 [Homo sapiens]                  32   1.4  
gi|51873049 hypothetical protein LOC8603 [Homo sapiens]                32   1.8  
gi|127138957 zinc finger protein 537 [Homo sapiens]                    32   1.8  
gi|7662162 ALEX2 protein [Homo sapiens]                                32   1.8  
gi|29540562 ALEX2 protein [Homo sapiens]                               32   1.8  
gi|160420295 hypothetical protein LOC85459 [Homo sapiens]              32   1.8  
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    31   3.1  
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    31   3.1  
gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo sapi...    31   3.1  
gi|92091575 coiled-coil domain containing 57 [Homo sapiens]            31   3.1  

>gi|29171682 interleukin 9 receptor precursor [Homo sapiens]
          Length = 521

 Score = 1105 bits (2858), Expect = 0.0
 Identities = 521/521 (100%), Positives = 521/521 (100%)

Query: 1   MGLGRCIWEGWTLESEALRRDMGTWLLACICICTCVCLGVSVTGEGQGPRSRTFTCLTNN 60
           MGLGRCIWEGWTLESEALRRDMGTWLLACICICTCVCLGVSVTGEGQGPRSRTFTCLTNN
Sbjct: 1   MGLGRCIWEGWTLESEALRRDMGTWLLACICICTCVCLGVSVTGEGQGPRSRTFTCLTNN 60

Query: 61  ILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSECTVVLPPEAVLVPSDNFTI 120
           ILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSECTVVLPPEAVLVPSDNFTI
Sbjct: 61  ILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSECTVVLPPEAVLVPSDNFTI 120

Query: 121 TFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNISSGHCILTWSISPALEPMTTLLS 180
           TFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNISSGHCILTWSISPALEPMTTLLS
Sbjct: 121 TFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNISSGHCILTWSISPALEPMTTLLS 180

Query: 181 YELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEER 240
           YELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEER
Sbjct: 181 YELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEER 240

Query: 241 YTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRVKRI 300
           YTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRVKRI
Sbjct: 241 YTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRVKRI 300

Query: 301 FYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLT 360
           FYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLT
Sbjct: 301 FYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLT 360

Query: 361 CGPARPWKSVALEEEQEGPGTRLPGNLSSEDVLPAGCTEWRVQTLAYLPQEDWAPTSLTR 420
           CGPARPWKSVALEEEQEGPGTRLPGNLSSEDVLPAGCTEWRVQTLAYLPQEDWAPTSLTR
Sbjct: 361 CGPARPWKSVALEEEQEGPGTRLPGNLSSEDVLPAGCTEWRVQTLAYLPQEDWAPTSLTR 420

Query: 421 PAPPDSEGSRSSSSSSSSNNNNYCALGCYGGWHLSALPGNTQSSGPIPALACGLSCDHQG 480
           PAPPDSEGSRSSSSSSSSNNNNYCALGCYGGWHLSALPGNTQSSGPIPALACGLSCDHQG
Sbjct: 421 PAPPDSEGSRSSSSSSSSNNNNYCALGCYGGWHLSALPGNTQSSGPIPALACGLSCDHQG 480

Query: 481 LETQQGVAWVLAGHCQRPGLHEDLQGMLLPSVLSKARSWTF 521
           LETQQGVAWVLAGHCQRPGLHEDLQGMLLPSVLSKARSWTF
Sbjct: 481 LETQQGVAWVLAGHCQRPGLHEDLQGMLLPSVLSKARSWTF 521


>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
          Length = 508

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 106/416 (25%), Positives = 156/416 (37%), Gaps = 92/416 (22%)

Query: 56  CLTNNILRIDCHWS-APELGQG-----------SSPWLLFTSNQAPGGTHK----CILRG 99
           C T  +  + C W  A   G G             PW L   +QAP         C L  
Sbjct: 52  CFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPT 111

Query: 100 SECTVVLPPEAVLVPSDNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNIS- 158
           ++ +  +P E + V + +    +H  +   E V L             D P  L + ++ 
Sbjct: 112 ADTSSFVPLE-LRVTAASGAPRYHRVIHINEVVLL-------------DAPVGLVARLAD 157

Query: 159 -SGHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPG 217
            SGH +L W + P   PMT+ + YE+       A    Q  + + G T  +L        
Sbjct: 158 ESGHVVLRW-LPPPETPMTSHIRYEVDVSAGNGAGS-VQRVEILEGRTECVLSNLRGRTR 215

Query: 218 FIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAV 277
           +    R R+           E  + G WS WS+PV    P    PLI        +L+ V
Sbjct: 216 YTFAVRARMA----------EPSFGGFWSAWSEPVSLLTPSDLDPLILTL-----SLILV 260

Query: 278 SIFLLLTGPTYLLFKLSPR--VKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVL 335
            I +LLT    +L  LS R  +K+  +  +PSP   F+ L++ H GNFQ W+     G L
Sbjct: 261 VILVLLT----VLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWL-YQNDGCL 315

Query: 336 LSQDCAGTPQGALEPCVQEATALLTCGPARPWKSVALEE---EQEGPGTRLPGNLSSEDV 392
               C         P  ++  A L     R W ++   E   + EGP     G+  ++D 
Sbjct: 316 WWSPCT--------PFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQD- 366

Query: 393 LPAGCTEWRVQTLAYLPQEDWA----PTSLTRPAPPDS-------EGSRSSSSSSS 437
                         YL  + W     P S   P P  S       EGS +SS SS+
Sbjct: 367 -------------TYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSA 409


>gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]
          Length = 551

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 75/287 (26%), Positives = 114/287 (39%), Gaps = 25/287 (8%)

Query: 54  FTCLTNNILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSE----CTVVL--P 107
           FTC  N+   I C WS     Q +S  +    ++        +L  S+    C ++L  P
Sbjct: 34  FTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAP 93

Query: 108 PEAVLVPSDNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQS-NISSGHCILTW 166
               L   D  T+    C  G     +   ++ P  +++L  P  LQ  ++ +  C ++W
Sbjct: 94  DSQKLTTVDIVTLRVL-CREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISW 152

Query: 167 SISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRV 226
            IS A       L +E         WE+A          W+ LE   L P   +E ++RV
Sbjct: 153 EISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLET--LTPDTQYEFQVRV 210

Query: 227 QMATLEDDVVEEERYTGQWSEWSQPVCFQA-PQRQGPLIPPWGWPGNTLVAVSIFLLLTG 285
           +    E            WS WSQP+ F+  P   G    PW   G+ LV +S       
Sbjct: 211 KPLQGEFTT---------WSPWSQPLAFRTKPAALGKDTIPW--LGHLLVGLSGAFGFII 259

Query: 286 PTYLLFKL---SPRVKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGA 329
             YLL       P +K++   N P P+ FF  L S H G+ Q W+ +
Sbjct: 260 LVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSS 306


>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 75/267 (28%), Positives = 110/267 (41%), Gaps = 42/267 (15%)

Query: 139 YLPRRHVKLDPPSDLQSNISSGHCILTWSIS---PALEPMTTLLSYELAFKKQEEAWEQA 195
           +L    +K  PP ++    S G   ++W      PA   +   L YEL ++ + + W  +
Sbjct: 112 FLLAESIKPAPPFNVTVTFS-GQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVS 170

Query: 196 QHRDHIV----GVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQP 251
             R  I      V+ L LE F  D  +     L+V+   +         Y G WSEWS P
Sbjct: 171 PRRKLISVDSRSVSLLPLE-FRKDSSY----ELQVRAGPMPGS-----SYQGTWSEWSDP 220

Query: 252 VCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRV---KRIFYQNVPSP 308
           V FQ    +       GW  + L+ + + ++   P +   K  P     K+I+   VPSP
Sbjct: 221 VIFQTQSEE----LKEGWNPHLLLLLLLVIVFI-PAFWSLKTHPLWRLWKKIWA--VPSP 273

Query: 309 AMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLTCGPAR-PW 367
             FF PLY   +G+F+ W+GA   G  L         G   P V     + +C P R P 
Sbjct: 274 ERFFMPLYKGCSGDFKKWVGAPFTGSSLE-------LGPWSPEVPSTLEVYSCHPPRSPA 326

Query: 368 KSVALEEEQEGPGTRLPGNLSSEDVLP 394
           K + L E QE      P  L   D +P
Sbjct: 327 KRLQLTELQE------PAELVESDGVP 347


>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 75/267 (28%), Positives = 110/267 (41%), Gaps = 42/267 (15%)

Query: 139 YLPRRHVKLDPPSDLQSNISSGHCILTWSIS---PALEPMTTLLSYELAFKKQEEAWEQA 195
           +L    +K  PP ++    S G   ++W      PA   +   L YEL ++ + + W  +
Sbjct: 112 FLLAESIKPAPPFNVTVTFS-GQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVS 170

Query: 196 QHRDHIV----GVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQP 251
             R  I      V+ L LE F  D  +     L+V+   +         Y G WSEWS P
Sbjct: 171 PRRKLISVDSRSVSLLPLE-FRKDSSY----ELQVRAGPMPGS-----SYQGTWSEWSDP 220

Query: 252 VCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRV---KRIFYQNVPSP 308
           V FQ    +       GW  + L+ + + ++   P +   K  P     K+I+   VPSP
Sbjct: 221 VIFQTQSEE----LKEGWNPHLLLLLLLVIVFI-PAFWSLKTHPLWRLWKKIWA--VPSP 273

Query: 309 AMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLTCGPAR-PW 367
             FF PLY   +G+F+ W+GA   G  L         G   P V     + +C P R P 
Sbjct: 274 ERFFMPLYKGCSGDFKKWVGAPFTGSSLE-------LGPWSPEVPSTLEVYSCHPPRSPA 326

Query: 368 KSVALEEEQEGPGTRLPGNLSSEDVLP 394
           K + L E QE      P  L   D +P
Sbjct: 327 KRLQLTELQE------PAELVESDGVP 347


>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 75/267 (28%), Positives = 110/267 (41%), Gaps = 42/267 (15%)

Query: 139 YLPRRHVKLDPPSDLQSNISSGHCILTWSIS---PALEPMTTLLSYELAFKKQEEAWEQA 195
           +L    +K  PP ++    S G   ++W      PA   +   L YEL ++ + + W  +
Sbjct: 112 FLLAESIKPAPPFNVTVTFS-GQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVS 170

Query: 196 QHRDHIV----GVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQP 251
             R  I      V+ L LE F  D  +     L+V+   +         Y G WSEWS P
Sbjct: 171 PRRKLISVDSRSVSLLPLE-FRKDSSY----ELQVRAGPMPGS-----SYQGTWSEWSDP 220

Query: 252 VCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLFKLSPRV---KRIFYQNVPSP 308
           V FQ    +       GW  + L+ + + ++   P +   K  P     K+I+   VPSP
Sbjct: 221 VIFQTQSEE----LKEGWNPHLLLLLLLVIVFI-PAFWSLKTHPLWRLWKKIWA--VPSP 273

Query: 309 AMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPCVQEATALLTCGPAR-PW 367
             FF PLY   +G+F+ W+GA   G  L         G   P V     + +C P R P 
Sbjct: 274 ERFFMPLYKGCSGDFKKWVGAPFTGSSLE-------LGPWSPEVPSTLEVYSCHPPRSPA 326

Query: 368 KSVALEEEQEGPGTRLPGNLSSEDVLP 394
           K + L E QE      P  L   D +P
Sbjct: 327 KRLQLTELQE------PAELVESDGVP 347


>gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo
           sapiens]
          Length = 371

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 58/229 (25%), Positives = 91/229 (39%), Gaps = 28/229 (12%)

Query: 179 LSYELAFKKQ-EEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVE 237
           L YE+ ++   +  W+  Q  ++   VT   +E  + +  +    R++       +DV  
Sbjct: 146 LLYEVQYRSPFDTEWQSKQ--ENTCNVT---IEGLDAEKCYSFWVRVKAM-----EDVYG 195

Query: 238 EERYTGQWSE---WSQ----PVCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLL 290
            + Y   WSE   W +      C + P    P +  +    +  + + + LLL      L
Sbjct: 196 PDTYPSDWSEVTCWQRGEIRDACAETPTPPKPKLSKFILISSLAILLMVSLLLLS----L 251

Query: 291 FKLSPRVKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQ--GAL 348
           +KL  RVK+    +VP P   F  L+ +H GNFQ W+      V      AG  Q  G  
Sbjct: 252 WKLW-RVKKFLIPSVPDPKSIFPGLFEIHQGNFQEWI-TDTQNVAHLHKMAGAEQESGPE 309

Query: 349 EPCVQEATALLTCGPARPWKSVALEEEQEGPGTRLPGN-LSSEDVLPAG 396
           EP V +        P R       E+E  G   +LP   L   DV+  G
Sbjct: 310 EPLVVQLAKTEAESP-RMLDPQTEEKEASGGSLQLPHQPLQGGDVVTIG 357


>gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo
           sapiens]
          Length = 259

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 57/229 (24%), Positives = 92/229 (40%), Gaps = 28/229 (12%)

Query: 179 LSYELAFKKQ-EEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVE 237
           L YE+ ++   +  W+  Q  ++   VT   +E  + +  +    R++       +DV  
Sbjct: 34  LLYEVQYRSPFDTEWQSKQ--ENTCNVT---IEGLDAEKCYSFWVRVKAM-----EDVYG 83

Query: 238 EERYTGQWSE---WSQ----PVCFQAPQRQGPLIPPWGWPGNTLVAVSIFLLLTGPTYLL 290
            + Y   WSE   W +      C + P    P +  +    +  + + + LLL      L
Sbjct: 84  PDTYPSDWSEVTCWQRGEIRDACAETPTPPKPKLSKFILISSLAILLMVSLLLLS----L 139

Query: 291 FKLSPRVKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGA--L 348
           +KL  RV++    +VP P   F  L+ +H GNFQ W+      V      AG  QG+   
Sbjct: 140 WKLW-RVRKFLIPSVPDPKSIFPGLFEIHQGNFQEWI-TDTQNVAHLHKMAGAEQGSGPE 197

Query: 349 EPCVQEATALLTCGPARPWKSVALEEEQEGPGTRLPGN-LSSEDVLPAG 396
           EP V +        P R       E+E  G   +LP   L   DV+  G
Sbjct: 198 EPLVVQLAKTEAESP-RMLDPQTEEKEASGGSLQLPHQPLQGGDVVTIG 245


>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 32/118 (27%), Positives = 56/118 (47%), Gaps = 13/118 (11%)

Query: 143 RHVKLDPPSDLQSNISSGHCILTWSISPALEPMTTL----LSYELAFKKQEEAWEQAQHR 198
           +HV+   P DLQ +    H +LTWS++        L    L +E+ +K+ +++WE A   
Sbjct: 129 QHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQDSWEDAAIL 188

Query: 199 DHIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQA 256
             +   +   L    L P   + AR+R ++A          R +G+ S+WS  VC+ +
Sbjct: 189 --LSNTSQATLGPEHLMPSSTYVARVRTRLA-------PGSRLSGRPSKWSPEVCWDS 237



 Score = 36.6 bits (83), Expect = 0.057
 Identities = 59/300 (19%), Positives = 112/300 (37%), Gaps = 63/300 (21%)

Query: 46  GQGPRSRTFTCLTNNILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSECTVV 105
           G   + +   C  +    + C W   +    S  + LF       G  +C          
Sbjct: 240 GDEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEEC---------- 289

Query: 106 LPPEAVLVPSDNFTITFHHCMSGREQVSLVDP----EYL----PRR---------HVKLD 148
                VL        T HHC     Q+ + DP    +Y+    PRR         ++++ 
Sbjct: 290 ---SPVLREGLGSLHTRHHC-----QIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMA 341

Query: 149 PPSDLQSNISSGHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLI 208
           PPS   +     + +   ++    E +    ++E+ ++K    W+ ++  + +     + 
Sbjct: 342 PPSLNVTKDGDSYSLRWETMKMRYEHIDH--TFEIQYRKDTATWKDSK-TETLQNAHSMA 398

Query: 209 LEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWG 268
           L A  L+P   + AR+RV+ +           Y G WSEWS+   +        ++P W 
Sbjct: 399 LPA--LEPSTRYWARVRVRTS--------RTGYNGIWSEWSEARSWDTES----VLPMW- 443

Query: 269 WPGNTLVAVSIFLLLTGPTYLLF--KLSPRVKRIFYQNVPSPAMFFQPLYSVHNGNFQTW 326
                L  + IFL +     L F      R++R + + +P+P+      +   NG+ + W
Sbjct: 444 ----VLALIVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPNPS----KSHLFQNGSAELW 495


>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
          Length = 958

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 18/115 (15%)

Query: 141 PRRHVKLDPPSDLQSNISS-GHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRD 199
           P   VK DPP  L   I+  G+  ++WS SP L P    L Y++  K  E +    +  D
Sbjct: 231 PINMVKPDPPLGLHMEITDDGNLKISWS-SPPLVPFP--LQYQV--KYSENSTTVIREAD 285

Query: 200 HIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCF 254
            IV  T L++++  + PG  +E ++R +               G WS+WS P  F
Sbjct: 286 KIVSATSLLVDS--ILPGSSYEVQVRGKRLD----------GPGIWSDWSTPRVF 328


>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
          Length = 896

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 18/115 (15%)

Query: 141 PRRHVKLDPPSDLQSNISS-GHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRD 199
           P   VK DPP  L   I+  G+  ++WS SP L P    L Y++  K  E +    +  D
Sbjct: 231 PINMVKPDPPLGLHMEITDDGNLKISWS-SPPLVPFP--LQYQV--KYSENSTTVIREAD 285

Query: 200 HIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCF 254
            IV  T L++++  + PG  +E ++R +               G WS+WS P  F
Sbjct: 286 KIVSATSLLVDS--ILPGSSYEVQVRGKRLD----------GPGIWSDWSTPRVF 328


>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
          Length = 1165

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 18/115 (15%)

Query: 141 PRRHVKLDPPSDLQSNISS-GHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRD 199
           P   VK DPP  L   I+  G+  ++WS SP L P    L Y++  K  E +    +  D
Sbjct: 231 PINMVKPDPPLGLHMEITDDGNLKISWS-SPPLVPFP--LQYQV--KYSENSTTVIREAD 285

Query: 200 HIVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCF 254
            IV  T L++++  + PG  +E ++R +               G WS+WS P  F
Sbjct: 286 KIVSATSLLVDS--ILPGSSYEVQVRGKRLD----------GPGIWSDWSTPRVF 328


>gi|28610151 interleukin 7 receptor precursor [Homo sapiens]
          Length = 459

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 18/118 (15%)

Query: 145 VKLDPPSDLQSNISSG--HCILTWSISPALEPMTTLLSYELAFK--KQEEAWEQAQHRDH 200
           VK + P DL      G    ++T++ S   +    +L +++A++  K E  W        
Sbjct: 127 VKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVN---- 182

Query: 201 IVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQ 258
            +  T L L   +L P  ++E ++R          + +  + G WSEWS    F+ P+
Sbjct: 183 -LSSTKLTLLQRKLQPAAMYEIKVRS---------IPDHYFKGFWSEWSPSYYFRTPE 230


>gi|4557040 oncostatin M receptor [Homo sapiens]
          Length = 979

 Score = 33.5 bits (75), Expect = 0.48
 Identities = 45/201 (22%), Positives = 77/201 (38%), Gaps = 25/201 (12%)

Query: 52  RTFTCLTNNILRIDCHWSA---PELGQGSSPWLLFTSNQAPGGTHKCILRGSECTVVLPP 108
           + F+C T +   + C W       LG    P   +T  ++  G  K     + C   +  
Sbjct: 241 KDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKNWCNWQITQ 300

Query: 109 EAVLVPSDNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNISSGHCILTWSI 168
           ++    + NFT+   + +  R    L +   L  R   ++P S    N+++ + I+TW +
Sbjct: 301 DSQ--ETYNFTLIAENYLRKRSVNILFN---LTHRVYLMNPFSVNFENVNATNAIMTWKV 355

Query: 169 SPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQM 228
                  T L   EL     E    Q      + G  +L     EL+P   + AR+R   
Sbjct: 356 HSIRNNFTYLCQIEL---HGEGKMMQYNVSIKVNGEYFL----SELEPATEYMARVRCAD 408

Query: 229 ATLEDDVVEEERYTGQWSEWS 249
           A+          +  +WSEWS
Sbjct: 409 AS----------HFWKWSEWS 419


>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
          Length = 422

 Score = 33.5 bits (75), Expect = 0.48
 Identities = 28/122 (22%), Positives = 48/122 (39%), Gaps = 14/122 (11%)

Query: 145 VKLDPPSDLQSNISSG---HCILTWSISPALEPMTTLLSYELAFKKQEEA-WEQAQHRDH 200
           V  DPP D+  +   G      + W   PAL+       Y++ ++ ++   W+     D 
Sbjct: 233 VTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVV---DD 289

Query: 201 IVGVTWLILEAFELDPGFIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQ 260
           +   T   L    L PG ++  ++R     +        +  G WSEWS P     P+ +
Sbjct: 290 VSNQTSCRLAG--LKPGTVYFVQVRCNPFGIYGS-----KKAGIWSEWSHPTAASTPRSE 342

Query: 261 GP 262
            P
Sbjct: 343 RP 344


>gi|13194201 reticulon 4 receptor precursor [Homo sapiens]
          Length = 473

 Score = 33.1 bits (74), Expect = 0.63
 Identities = 41/166 (24%), Positives = 60/166 (36%), Gaps = 17/166 (10%)

Query: 333 GVLLSQDCAGTPQGALEPCVQEATALLTCGPARPWKSVALEEEQEGPGTRLPGNLSSEDV 392
           G    ++  G P+        +A+ L    P RP  +    + +  PG   PGN S    
Sbjct: 322 GRATDEEPLGLPKCCQPDAADKASVL---EPGRPASAGNALKGRVPPGDSPPGNGSG--- 375

Query: 393 LPAGCTEWRVQTL---AYLPQEDWAPTSLTRPAPPDSEGSRSSSSSSSSNNNNYCALGCY 449
            P    +    TL   A  P     P     P  P S   R    S  +   ++C LG  
Sbjct: 376 -PRHINDSPFGTLPGSAEPPLTAVRPEGSEPPGFPTSGPRRRPGCSRKNRTRSHCRLGQA 434

Query: 450 GGWHLSALPGNTQSSGPIPALACGLSCDHQGLETQQGVAWVLAGHC 495
           G        G+++ SG +P+L C L+     L     V W + G C
Sbjct: 435 GSG--GGGTGDSEGSGALPSLTCSLTPLGLAL-----VLWTVLGPC 473


>gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo
           sapiens]
          Length = 539

 Score = 33.1 bits (74), Expect = 0.63
 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 2/57 (3%)

Query: 381 TRLPGNLSSEDVLPAGCTEWRVQTLAYLPQEDWAPTSLTRPAPPDSEGSRSSSSSSS 437
           T+  G+L++E  LP+  T +   T + +P   + P+S T PAP   E SR     S+
Sbjct: 318 TQKLGSLNNEPALPS--TSYLPSTPSVVPASSYIPSSETPPAPSSREASRPPEEPSA 372


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 32.7 bits (73), Expect = 0.83
 Identities = 17/32 (53%), Positives = 22/32 (68%)

Query: 409 PQEDWAPTSLTRPAPPDSEGSRSSSSSSSSNN 440
           P ++ AP+S   P PP S GS SSSSSSS ++
Sbjct: 797 PPKESAPSSGPPPKPPVSSGSGSSSSSSSCSS 828


>gi|24497517 homeobox A5 [Homo sapiens]
          Length = 270

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 4/88 (4%)

Query: 378 GPGTRLPGNLSSEDVLPAGCTEWRVQTLAYLPQEDWAPTSLTRPAPPDSEGSRSSSSSSS 437
           G G R     +S    PA     +  T  + PQ D  P S   P+P    GS S     +
Sbjct: 65  GSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSP----GSDSHHGGKN 120

Query: 438 SNNNNYCALGCYGGWHLSALPGNTQSSG 465
           S +N+  A    G  H+S+  G   +SG
Sbjct: 121 SLSNSSGASADAGSTHISSREGVGTASG 148


>gi|40807477 retinoic acid induced 1 [Homo sapiens]
          Length = 1906

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 19/102 (18%)

Query: 342  GTPQGALEPCVQEATALLTCGPARPWKSVALEEEQEGP------GTRLPGNLSSEDVLPA 395
            G P+    PC           P  P K + L E   GP      G   PG  +SE  LP 
Sbjct: 1006 GLPEAEDSPCR---------APVLP-KDLLLPESCTGPPQGQMEGAGAPGRGASEG-LPR 1054

Query: 396  GCTEWRVQTLAYLPQEDWAPTSLTRPAPPDSEGSRSSSSSSS 437
             CT  R  T    P+    P   T PAPPD  G +  ++  S
Sbjct: 1055 MCT--RSLTALSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKS 1094


>gi|61966721 Tctex1 domain containing 4 [Homo sapiens]
          Length = 221

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 26/92 (28%), Positives = 35/92 (38%), Gaps = 7/92 (7%)

Query: 384 PGNLSSEDVLPAGCTEWRVQTLAYLPQEDWAPTSLTRPAPPDSEGSRSSSSSSSSNNNNY 443
           PG    E+   +G     V+    LP  D A  +   PAP    GS    ++S S  N+ 
Sbjct: 8   PGRQEEENAKDSGRKPSPVRPRGCLPSIDEARPAGPGPAPASRRGSMLGLAASFSRRNSL 67

Query: 444 CALGCYGGWHLSALPGNTQSSGPIPALACGLS 475
              G   G       G   S GP+P L   +S
Sbjct: 68  VGPGAGPG-------GQRPSLGPVPPLGSRVS 92


>gi|51873049 hypothetical protein LOC8603 [Homo sapiens]
          Length = 1224

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 7/74 (9%)

Query: 367 WKSVALEEEQEGPGTRLPGNLSSEDVLPAGCTEWRVQTLAYLPQEDWAPTSLTRPAPPDS 426
           W S  + ++   PGT LP  +S  ++L    +E R + L         P+S   PA  DS
Sbjct: 531 WGSEVMNDKNWNPGTFLPDTISGSEILGPTLSETRPEALP-------PPSSNETPAVSDS 583

Query: 427 EGSRSSSSSSSSNN 440
           +  ++++      N
Sbjct: 584 KEKKNAAKKKCLYN 597


>gi|127138957 zinc finger protein 537 [Homo sapiens]
          Length = 1081

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 407 YLPQEDWAPTSLTRPAPPDSEGSRSSSSSSSSNNNNYCALGCYGGWHLSALPGNTQ 462
           +L    W+  +L    P   + + SSSSSSSS+++  C  G +  WH SA+    Q
Sbjct: 125 FLSNSYWSNLNLNLHQPSSEKNNGSSSSSSSSSSS--CGSGSF-DWHQSAMAKTLQ 177


>gi|7662162 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 8/129 (6%)

Query: 341 AGTPQGALEPCVQEAT-ALLTCGPARPWKSVALEEEQEGPGTRLPGNLSSEDVLPAGCTE 399
           AG P+ A  P   E + A +  G   P ++ A  E  EGPG   P  ++    + A  TE
Sbjct: 158 AGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGV-ASPTE 216

Query: 400 WRVQTLAYLPQEDWAPTSLTRPAPPDSEGSRSSSSSSSSNNNNYCALGCYGGWHLSALPG 459
                +   P    APT     +P  S   R++    +S      A     G H  A+P 
Sbjct: 217 AAEAPVPATPTGAAAPTGAAE-SPGTSGSPRTAVVPGTS-----AAKKATPGAHTGAIPK 270

Query: 460 NTQSSGPIP 468
            T ++G +P
Sbjct: 271 ATSATGAVP 279


>gi|29540562 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 8/129 (6%)

Query: 341 AGTPQGALEPCVQEAT-ALLTCGPARPWKSVALEEEQEGPGTRLPGNLSSEDVLPAGCTE 399
           AG P+ A  P   E + A +  G   P ++ A  E  EGPG   P  ++    + A  TE
Sbjct: 158 AGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGV-ASPTE 216

Query: 400 WRVQTLAYLPQEDWAPTSLTRPAPPDSEGSRSSSSSSSSNNNNYCALGCYGGWHLSALPG 459
                +   P    APT     +P  S   R++    +S      A     G H  A+P 
Sbjct: 217 AAEAPVPATPTGAAAPTGAAE-SPGTSGSPRTAVVPGTS-----AAKKATPGAHTGAIPK 270

Query: 460 NTQSSGPIP 468
            T ++G +P
Sbjct: 271 ATSATGAVP 279


>gi|160420295 hypothetical protein LOC85459 [Homo sapiens]
          Length = 2601

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 26/97 (26%), Positives = 39/97 (40%), Gaps = 6/97 (6%)

Query: 412  DWAPTSLTRPAPPDSEGSRSSSSSSSSNNN--NYCALGCYGGWHLSALPGNTQSSGPIPA 469
            DW P +    A  D E  R +  ++S +N+  +        G HL    G   S  P+  
Sbjct: 1778 DWFPNTQDL-AGNDQENIRHADRNNSDDNHLASEDTSAKQSGEHLEKDLGRRSSKPPVAK 1836

Query: 470  LACGLSCDHQGLETQQGVAWVLAGHCQ---RPGLHED 503
            + CGL  +   L   Q V     G      +PG++ED
Sbjct: 1837 VKCGLDLNQHELSAIQEVESPAIGRTSILGKPGIYED 1873


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 409 PQEDWAPTSLTRP---APPDSEGSRSSSSSSSSNNNN 442
           PQ D+ P S  +P    P  S  S SSSSSSSS++++
Sbjct: 75  PQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSS 111


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 409 PQEDWAPTSLTRP---APPDSEGSRSSSSSSSSNNNN 442
           PQ D+ P S  +P    P  S  S SSSSSSSS++++
Sbjct: 75  PQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSS 111


>gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo
           sapiens]
          Length = 427

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 27/117 (23%)

Query: 216 PGFIHEARLRVQMATL--EDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNT 273
           P  ++  R+RV+   L  EDD +        WS WSQ +               G   N+
Sbjct: 304 PDTLNTVRIRVKTNKLCYEDDKL--------WSNWSQEMSI-------------GKKRNS 342

Query: 274 LVAVSIFLLL----TGPTYLLFKLSPRVKRIFYQNVPSPAMFFQPLYSVHNGNFQTW 326
            + +++ L++     G   +L     R+K I +  +P P   F+ ++   N +   W
Sbjct: 343 TLYITMLLIVPVIVAGAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHW 399


>gi|92091575 coiled-coil domain containing 57 [Homo sapiens]
          Length = 915

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 40/172 (23%), Positives = 62/172 (36%), Gaps = 28/172 (16%)

Query: 331 GAGVLLSQDCAGTPQGALEPCVQEATALLTCGPARPWKSVALEEEQEGPGTRLPGNL--- 387
           G  + ++Q     P G  +P   +A AL         +  A   E E P   L  +    
Sbjct: 717 GKHLRIAQHGGAEPSGRKQPPASDAVAL--------GREDAKSAEDEAPSRHLGKHQPRS 768

Query: 388 ----SSEDVLPAGCTEWRVQTLAYLP---QEDWAPTSLTRPAPPDSEGSRSSSSSSSSNN 440
               S  D L    T+  + T+       +ED +P     P  P+  G +S SSSS ++ 
Sbjct: 769 AQVGSRLDALQGPKTQHSIHTVTCKSPRQKEDRSPKPPQAPQHPEEHGRQSHSSSSFASG 828

Query: 441 NNYCALGCYGGWHL----SALPGNTQSSGPIPALACGLSCDHQGLETQQGVA 488
                      W L    S+  G T      P L    + D + ++ Q G+A
Sbjct: 829 T------LQDMWRLLDLGSSPSGVTSQGDSTPELPAPPAADRRPVKMQAGIA 874


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,272,317
Number of Sequences: 37866
Number of extensions: 1353292
Number of successful extensions: 4637
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 4482
Number of HSP's gapped (non-prelim): 135
length of query: 521
length of database: 18,247,518
effective HSP length: 107
effective length of query: 414
effective length of database: 14,195,856
effective search space: 5877084384
effective search space used: 5877084384
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.