Guide to the Human Genome
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Search of human proteins with 28559071

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c
[Homo sapiens]
         (166 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Ho...   338   2e-93
gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho...   308   2e-84
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho...   308   2e-84
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    53   1e-07
gi|5032169 telomeric repeat binding factor 2 [Homo sapiens]            46   2e-05
gi|33286446 opioid growth factor receptor [Homo sapiens]               45   2e-05
gi|91208420 bassoon protein [Homo sapiens]                             45   2e-05
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s...    45   3e-05
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    45   3e-05
gi|30795231 brain abundant, membrane attached signal protein 1 [...    45   4e-05
gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]            45   4e-05
gi|51873049 hypothetical protein LOC8603 [Homo sapiens]                45   4e-05
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    44   5e-05
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ...    44   8e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   8e-05
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H...    42   2e-04
gi|38372931 brevican isoform 2 [Homo sapiens]                          42   2e-04
gi|38372935 brevican isoform 1 [Homo sapiens]                          42   2e-04
gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens]     42   2e-04
gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens]       42   2e-04
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       42   3e-04
gi|11560152 zinc finger protein 335 [Homo sapiens]                     42   3e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    42   3e-04
gi|194272140 dendrin [Homo sapiens]                                    41   4e-04
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    41   5e-04
gi|14993776 skeletal myosin light chain kinase [Homo sapiens]          41   5e-04
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]    40   7e-04
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]    40   7e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              40   7e-04
gi|6912492 mitogen-activated protein kinase 8 interacting protei...    40   7e-04

>gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Homo
           sapiens]
          Length = 166

 Score =  338 bits (866), Expect = 2e-93
 Identities = 166/166 (100%), Positives = 166/166 (100%)

Query: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60
           MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV
Sbjct: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60

Query: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120
           ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG
Sbjct: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120

Query: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTSIP 166
           AAETLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTSIP
Sbjct: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTSIP 166


>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score =  308 bits (788), Expect = 2e-84
 Identities = 150/151 (99%), Positives = 151/151 (100%)

Query: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60
           MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV
Sbjct: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60

Query: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120
           ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG
Sbjct: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120

Query: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGE 151
           AAETLPEASRAVENGCCTPKEGRGAPAEAG+
Sbjct: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGK 151


>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score =  308 bits (788), Expect = 2e-84
 Identities = 150/151 (99%), Positives = 151/151 (100%)

Query: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60
           MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV
Sbjct: 1   MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60

Query: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120
           ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG
Sbjct: 61  ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG 120

Query: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGE 151
           AAETLPEASRAVENGCCTPKEGRGAPAEAG+
Sbjct: 121 AAETLPEASRAVENGCCTPKEGRGAPAEAGK 151


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 40/142 (28%), Positives = 54/142 (38%), Gaps = 2/142 (1%)

Query: 25  DGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGA 84
           D EE  E  G   RQ+PS  + ++ RP      P   +G T    + +  + S     GA
Sbjct: 27  DEEEDAEEEGAGGRQDPSRRSIRL-RP-LPSPSPSAAAGGTESRSSALGAADSEGPARGA 84

Query: 85  SELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRG 144
            +   NGD  +        GS  GG  G       G      E  R +  G  +P E R 
Sbjct: 85  GKSSTNGDCRRFRGSLASLGSRGGGSGGTGSGSSHGHLHDSAEERRLIAEGDASPGEDRT 144

Query: 145 APAEAGESSAPGAASSGPTSIP 166
            P  A E   PGA++    S P
Sbjct: 145 PPGLAAEPERPGASAQPAASPP 166



 Score = 29.3 bits (64), Expect = 1.6
 Identities = 42/175 (24%), Positives = 54/175 (30%), Gaps = 21/175 (12%)

Query: 5    PSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTA------RKVGRPGRKRKHP 58
            PSS PG       E       G          + + PS  A        VG   R    P
Sbjct: 968  PSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVGFTPRGGLSP 1027

Query: 59   PVESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSP--AGGQ------ 110
            P   G +P  P     +P  A  S  S LLP        +     G+P    G+      
Sbjct: 1028 P---GHSPGPPRTFPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGTPPLTPGRLTQDLK 1084

Query: 111  --KGGAPAEGEGAAETLPEAS--RAVENGCCTPKEGRGAPAEAGESSAPGAASSG 161
                  PA  +  A+TL  AS   + E+    P   R      G  S+ G    G
Sbjct: 1085 LISASQPALPQDGAQTLRRASPHSSGESMAAFPLFPRAGGGSGGSGSSGGLGPPG 1139


>gi|5032169 telomeric repeat binding factor 2 [Homo sapiens]
          Length = 500

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 40/151 (26%), Positives = 63/151 (41%), Gaps = 22/151 (14%)

Query: 27  EEQEEPRGKEERQE-PSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGAS 85
           E      GKE++Q  P    +    P R+ ++PP   G      A   K+ S AQDS A+
Sbjct: 247 ESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAF--KTLSGAQDSEAA 304

Query: 86  -------------ELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAV 132
                        + LP     K   P+ +E       +  APA+GEG +E  P+  R  
Sbjct: 305 FAKLDQKDLVLPTQALPASPALKNKRPRKDEN------ESSAPADGEGGSELQPKNKRMT 358

Query: 133 ENGCCTPKEGRGAPAEAGESSAPGAASSGPT 163
            +     ++ +     AG +S+  AAS+ P+
Sbjct: 359 ISRLVLEEDSQSTEPSAGLNSSQEAASAPPS 389


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 45.4 bits (106), Expect = 2e-05
 Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 11/139 (7%)

Query: 26  GEEQEEPRGKEERQEPSTTA--RKVGRPGRKRKHPPVES-GDTPKDPAVISKSPSMAQDS 82
           G     P G E  + PS T   R  G  G +    P E+ G  P  PA    + S ++  
Sbjct: 523 GPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 582

Query: 83  GASELLPNGD--LEKRSE-PQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTP 139
           G S   P  D   E  SE P P    PAG +   +P+E  G     P      E+   TP
Sbjct: 583 GPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 642

Query: 140 KEG-----RGAPAEAGESS 153
                   R  PA+AGE++
Sbjct: 643 GPSPAGPTRDEPAKAGEAA 661



 Score = 43.9 bits (102), Expect = 6e-05
 Identities = 44/167 (26%), Positives = 59/167 (35%), Gaps = 11/167 (6%)

Query: 5   PSSGP-GDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESG 63
           PS  P    S +  E + + + G ++  P    E   PS        P       P   G
Sbjct: 487 PSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP---G 543

Query: 64  DTPKDPAVISKSPSMAQDSGASELLPNGD--LEKRSE-PQPEEGSPAGGQKGGAPAEGEG 120
             P  PA    + S ++  G     P GD   E  SE P P    P   +   +P+E  G
Sbjct: 544 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG 603

Query: 121 AAETLPEASRAVENGCCTPKEGRGAPA--EAGE--SSAPGAASSGPT 163
                P      E+   TP      PA  E  E  S  PG + +GPT
Sbjct: 604 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 650



 Score = 34.7 bits (78), Expect = 0.038
 Identities = 36/140 (25%), Positives = 47/140 (33%), Gaps = 11/140 (7%)

Query: 5   PSSGPGDTSSSAAEREE----DRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV 60
           PS  PG   +  A  E         G     P G E  + PS T      P    +  P 
Sbjct: 538 PSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP--SPAGPTRDEPA 595

Query: 61  ES-----GDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAP 115
           ES     G  P  PA    + S ++  G     P GD    S  +    SPAG  +    
Sbjct: 596 ESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655

Query: 116 AEGEGAAETLPEASRAVENG 135
             GE A     E   + ++G
Sbjct: 656 KAGEAAELQDAEVESSAKSG 675


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 45.4 bits (106), Expect = 2e-05
 Identities = 44/187 (23%), Positives = 66/187 (35%), Gaps = 28/187 (14%)

Query: 2    PAMPSSG-PGDTSS----------SAAEREEDRKDGEEQEE--PRGKEERQEPSTTARKV 48
            PAMP  G PG  SS          SA     D K G  Q    P   + + EP    +  
Sbjct: 3689 PAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQ 3748

Query: 49   GR---PGRKRKHPP----VESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQP 101
            GR   PG ++   P    + SG   + P    +   +       + L    L+++S+P  
Sbjct: 3749 GRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQP-PQQALTQARLQQQSQPTT 3807

Query: 102  EEGSPAGGQKGGAPAEG-------EGAAETLPEASRAVENGCCTPKEGRGAPAEAGESSA 154
               +PA  Q  G P  G       + A     E +   +     P++GR   A+      
Sbjct: 3808 RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPG 3867

Query: 155  PGAASSG 161
            P    +G
Sbjct: 3868 PAGVKAG 3874



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 38/159 (23%), Positives = 57/159 (35%), Gaps = 17/159 (10%)

Query: 15  SAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISK 74
           S A++   + D E    P G +     + TAR    PG  +   P E G     P     
Sbjct: 252 SPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQP----- 306

Query: 75  SPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQ-KGGAPAEGEG-AAETLPEASRAV 132
            P   + S A    P G+   +S      G  A  Q + G   +  G  A  L +AS  +
Sbjct: 307 -PQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLM 365

Query: 133 ENGCCTPKEGRGAPA---------EAGESSAPGAASSGP 162
                   +G+ AP+         +A + + P    SGP
Sbjct: 366 SVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP 404


>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
           sapiens]
          Length = 758

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 44/161 (27%), Positives = 63/161 (39%), Gaps = 21/161 (13%)

Query: 24  KDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDT---PKDPAVISKSPSMAQ 80
           KDG   ++ + K   +  + T +   RP    KHP   S D    P  PAV  + PS  +
Sbjct: 383 KDGTGSDDKKAKTSTRSSAKTLKN--RPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPK 440

Query: 81  ----------DSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGA-----PAEGEGAAETL 125
                      SGA E+   G   K     P   +P  GQKG A     PA+   A +T 
Sbjct: 441 HVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPP-GQKGQANATRIPAKTPPAPKTP 499

Query: 126 PEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTSIP 166
           P +    ++G  +     G+P   G  S   +  + PT  P
Sbjct: 500 PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 540


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 11/136 (8%)

Query: 11  DTSSSAAEREEDRKDGEEQEE-PRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTP--- 66
           D SSS+ E  E +    +QEE P+G +E+ + S  + +   P   ++    +   TP   
Sbjct: 276 DGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEK 335

Query: 67  ---KDPAVISKSPSMAQ-DSGASELL--PNGDLEKRSEPQPEEGSPAGGQKGGAP-AEGE 119
              KD +  S S   +  DS AS  L         + E +P  GS  G  + G P AEG 
Sbjct: 336 KRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGG 395

Query: 120 GAAETLPEASRAVENG 135
             + TL  A+  +E G
Sbjct: 396 STSSTLRAAASKLEQG 411



 Score = 29.3 bits (64), Expect = 1.6
 Identities = 26/122 (21%), Positives = 46/122 (37%), Gaps = 27/122 (22%)

Query: 19  REEDRKDGEEQEEPRGKEERQE----------------PSTTARKVGRPGRKRKHPPVES 62
           +++D+ + EE++E RG+ +  E                   +  + GR  + +K  P+  
Sbjct: 183 KDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAK 242

Query: 63  GDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQ----KGGAPAEG 118
           G          K      D  A E   +GD E +      +GS +  +    K  AP + 
Sbjct: 243 GGR-------KKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQE 295

Query: 119 EG 120
           EG
Sbjct: 296 EG 297


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 42/168 (25%), Positives = 72/168 (42%), Gaps = 24/168 (14%)

Query: 9   PGDTSSSAAEREEDRKDGE--EQEEPRGKEERQEPSTTARKVG--RPGRKRKHP-PVESG 63
           P   +   AE +E  KD    ++E P+ + E+ E +  A+      P +++  P P   G
Sbjct: 58  PDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGG 117

Query: 64  DTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPA------E 117
           + PK  A  + +P+ +    A E           EP  EEG P   +   APA      +
Sbjct: 118 EAPK-AAEAAAAPAESAAPAAGE-----------EPSKEEGEPKKTEAPAAPAAQETKSD 165

Query: 118 GEGAAETLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTSI 165
           G  A+++ P +S A  +   TP     AP+   ++  P A++  P  +
Sbjct: 166 GAPASDSKPGSSEAAPSSKETP-AATEAPSSTPKAQGPAASAEEPKPV 212


>gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 235

 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 45/139 (32%), Positives = 57/139 (41%), Gaps = 21/139 (15%)

Query: 33  RGKEERQEPSTTARKVGRPGRKR--KHPPVESGDTPKDPAVISKSPSMAQDSGASELLPN 90
           RG+ ER+     A K G PGR+R  K PP     T   P    + PS  QD+G +     
Sbjct: 77  RGRAERRSMQAAAAKAGSPGRRRVGKGPPSRESWTRSAP---QRCPS--QDAGRA----- 126

Query: 91  GDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAE---TLPEASRAVENGCCTPKEGRGAPA 147
           G    RS PQ   G  A     GA   G G  E     P A+ A   G  + K+    P 
Sbjct: 127 GSRVCRSRPQSRGGQKAAA--SGAKRRGVGGKEPRRQKPAAAGAKSRGGKSHKK----PR 180

Query: 148 EAGESSAPGAASSGPTSIP 166
             G+ +AP   S G  + P
Sbjct: 181 RRGQKAAPAKNSGGGGNKP 199


>gi|51873049 hypothetical protein LOC8603 [Homo sapiens]
          Length = 1224

 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 3/131 (2%)

Query: 18   EREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPS 77
            +R  + ++ EE+EE R KEE Q      +K+    +K+K  P  S D PK   +     +
Sbjct: 901  QRRREEEEDEEEEEDRFKEEFQRLQEL-QKLRAVKKKKKERP--SKDCPKLDMLTRNFQA 957

Query: 78   MAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCC 137
              +    S  + NG LE+  EP+    SP+       P  G GA     +     ++   
Sbjct: 958  ATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFL 1017

Query: 138  TPKEGRGAPAE 148
             PKE  G   E
Sbjct: 1018 LPKEVNGKQHE 1028



 Score = 28.1 bits (61), Expect = 3.6
 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 6/46 (13%)

Query: 12  TSSSAAEREEDRKDGEEQEEPRG--KEE----RQEPSTTARKVGRP 51
           TSSS++E +++  DGE   EP G  KE+     + P T   K   P
Sbjct: 349 TSSSSSEADDEEADGESSGEPPGAPKEDGVLGSRSPRTEESKADSP 394


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 10/122 (8%)

Query: 3   AMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVES 62
           A    GPG       + EED ++ EE EE   ++E +EP   A+ +G+  +    PP  +
Sbjct: 65  AASGGGPG------GDEEEDEEEEEEDEEALLEDEDEEP-PPAQALGQAAQPPPEPPEAA 117

Query: 63  G-DTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGA 121
             +   +P    K       SG         L KR E +PEE S  G +  G+   G+ A
Sbjct: 118 AMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKREEDEPEERS--GDETPGSEVPGDKA 175

Query: 122 AE 123
           AE
Sbjct: 176 AE 177


>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
           sapiens]
          Length = 776

 Score = 43.5 bits (101), Expect = 8e-05
 Identities = 48/164 (29%), Positives = 68/164 (41%), Gaps = 26/164 (15%)

Query: 24  KDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDT---PKDPAVISKSPSMAQ 80
           KDG   ++ + K   +  + T +   RP    KHP   S D    P  PAV  + PS  +
Sbjct: 383 KDGTGSDDKKAKTSTRSSAKTLKN--RPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPK 440

Query: 81  ----------DSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGA-----PAEGEGAAETL 125
                      SGA E+   G   K     P   +P  GQKG A     PA+   A +T 
Sbjct: 441 HVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPP-GQKGQANATRIPAKTPPAPKTP 499

Query: 126 P-EASRAVEN--GCCTPKEGRGAPAEAGESSAPGAASSGPTSIP 166
           P  A++ V+       P+  RG P ++G+ S  G +S G    P
Sbjct: 500 PSSATKQVQRRPPPAGPRSERGEPPKSGDRS--GYSSPGSPGTP 541


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 43.5 bits (101), Expect = 8e-05
 Identities = 47/175 (26%), Positives = 68/175 (38%), Gaps = 26/175 (14%)

Query: 12  TSSSAAEREEDRKDGEEQEEPRGKEERQE------PSTTARKVGRPGRKRKHPPVESGDT 65
           T     E E++ K+ E +EE  G+EE  E       S  A +   P ++ K P  E   +
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526

Query: 66  P-----------KDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPA---GGQK 111
           P           K PA + KSP  A+     E       E +S  + E  SPA     +K
Sbjct: 527 PAEAKSPEKEEAKSPAEV-KSPEKAKSPAKEE--AKSPPEAKSPEKEEAKSPAEVKSPEK 583

Query: 112 GGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTSIP 166
             +PA+ E  +   P  +++ E      KE   +PAEA       A S      P
Sbjct: 584 AKSPAKEEAKS---PAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 6/122 (4%)

Query: 15  SAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISK 74
           S  + EE  ++ + +E P+  EE + P+T   +  +  +K + P  E+   PK      K
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA---PKPKVEEKK 878

Query: 75  SPSMAQDSGASELLPNGDLE-KRSEPQPEEGSPAGGQ--KGGAPAEGEGAAETLPEASRA 131
            P++ +   +       + E K+  P PE+ +PA  +  +   P E    A+  P+ ++A
Sbjct: 879 EPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKA 938

Query: 132 VE 133
            E
Sbjct: 939 KE 940



 Score = 32.3 bits (72), Expect = 0.19
 Identities = 36/163 (22%), Positives = 66/163 (40%), Gaps = 15/163 (9%)

Query: 11  DTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPA 70
           + + S AE +   K  EE + P   +  ++  + A++  +   + K P  E   +P +  
Sbjct: 522 EEAKSPAEAKSPEK--EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK 579

Query: 71  VISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGG-----QKGGAPAE---GEGAA 122
              K+ S A++   S        + +S  + E  SPA       ++  +PAE    E A 
Sbjct: 580 SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK 639

Query: 123 ETLPEASRAVENGCCTPKEGRGAPAEA-----GESSAPGAASS 160
               E +++ E      KE   +P +A      E+ +P  A S
Sbjct: 640 SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682



 Score = 28.9 bits (63), Expect = 2.1
 Identities = 22/101 (21%), Positives = 41/101 (40%), Gaps = 9/101 (8%)

Query: 14   SSAAEREEDRKDGEEQEEPRGKEER--QEPSTTARKVGRPGRKRKHPPVESGDTPKDPAV 71
            +  A++E D    +E  +P  K+E   ++  T   K  +P  K    P       +D   
Sbjct: 926  TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK----PKTEAKAKEDDKT 981

Query: 72   ISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKG 112
            +SK PS  +   A +   +   +++    PE+ +     KG
Sbjct: 982  LSKEPSKPKAEKAEK---SSSTDQKDSKPPEKATEDKAAKG 1019


>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
            sapiens]
          Length = 1447

 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)

Query: 13   SSSAAEREEDRKDGEEQ---EEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDP 69
            S  + +R     + +EQ   EE R KE+  E         + G++ + P    G TPK+ 
Sbjct: 1246 SQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEE 1305

Query: 70   AVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEAS 129
              +  S   ++           + E+R     E+ S +   +    A+    +   PE+S
Sbjct: 1306 PTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAES---PESS 1362

Query: 130  RAVENGCCTPKEGRGAPAEAGESSAP 155
             A+E+   TP++GRG P++    S P
Sbjct: 1363 -AIESTQSTPQKGRGRPSKTPSPSQP 1387


>gi|38372931 brevican isoform 2 [Homo sapiens]
          Length = 671

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 47/173 (27%), Positives = 74/173 (42%), Gaps = 26/173 (15%)

Query: 4   MPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTA--RKVGRPGRKRKHPPVE 61
           +P +G  +    A E EE  +D EE+EE   +EE ++ +  A   ++  PG         
Sbjct: 440 VPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPG--------P 491

Query: 62  SGDTPKDPAV----ISKSPSMAQDSGASELLPNGDLEKRSEPQ----PEEGSPAGGQKGG 113
               P +PA     +S++P+ A     +  LP+G+ E    P+    P E  P   ++  
Sbjct: 492 EASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNL 551

Query: 114 APAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTSIP 166
           A      +  TL EA R V      P E  G P   GES   G++   P+ +P
Sbjct: 552 A----SPSPSTLVEA-REVGEATGGP-ELSGVP--RGESEETGSSEGAPSLLP 596


>gi|38372935 brevican isoform 1 [Homo sapiens]
          Length = 911

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 47/173 (27%), Positives = 74/173 (42%), Gaps = 26/173 (15%)

Query: 4   MPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTA--RKVGRPGRKRKHPPVE 61
           +P +G  +    A E EE  +D EE+EE   +EE ++ +  A   ++  PG         
Sbjct: 440 VPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPG--------P 491

Query: 62  SGDTPKDPAV----ISKSPSMAQDSGASELLPNGDLEKRSEPQ----PEEGSPAGGQKGG 113
               P +PA     +S++P+ A     +  LP+G+ E    P+    P E  P   ++  
Sbjct: 492 EASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNL 551

Query: 114 APAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTSIP 166
           A      +  TL EA R V      P E  G P   GES   G++   P+ +P
Sbjct: 552 A----SPSPSTLVEA-REVGEATGGP-ELSGVP--RGESEETGSSEGAPSLLP 596


>gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens]
          Length = 274

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 41/155 (26%), Positives = 60/155 (38%), Gaps = 29/155 (18%)

Query: 16  AAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKD------- 68
           AAE E ++KD  E     G E++ E +TTA      G K   P  ++G+TP +       
Sbjct: 97  AAEAEANKKD--EAPVADGVEKKGEGTTTAEAAPATGSKPDEPG-KAGETPSEEKKGEGD 153

Query: 69  ----------PAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEG 118
                     PA   +    A+   A++   +     ++E  P +  P   ++   PA  
Sbjct: 154 AATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEP---KQADVPAAV 210

Query: 119 EGAAETLPEASRAVENGCCTPKEGRGAPAEAGESS 153
             AA T P A  A       P      P E GESS
Sbjct: 211 TAAAATTPAAEDAAAKATAQP------PTETGESS 239


>gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens]
          Length = 238

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 41/155 (26%), Positives = 60/155 (38%), Gaps = 29/155 (18%)

Query: 16  AAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKD------- 68
           AAE E ++KD  E     G E++ E +TTA      G K   P  ++G+TP +       
Sbjct: 61  AAEAEANKKD--EAPVADGVEKKGEGTTTAEAAPATGSKPDEPG-KAGETPSEEKKGEGD 117

Query: 69  ----------PAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEG 118
                     PA   +    A+   A++   +     ++E  P +  P   ++   PA  
Sbjct: 118 AATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEP---KQADVPAAV 174

Query: 119 EGAAETLPEASRAVENGCCTPKEGRGAPAEAGESS 153
             AA T P A  A       P      P E GESS
Sbjct: 175 TAAAATTPAAEDAAAKATAQP------PTETGESS 203


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 49/176 (27%), Positives = 60/176 (34%), Gaps = 18/176 (10%)

Query: 2    PAMPSSG--PGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPP 59
            P +P  G  PG       + E           P+G      P  +   VG PG     PP
Sbjct: 1293 PGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPG--PP 1350

Query: 60   VESGDTPKDPAVISKS----PSMAQDSGAS-ELLPNGDLEKRSEPQPEEGSPAGGQKGGA 114
             E G   +D     K     P      G + E  P+G   KR  P P       G+KG  
Sbjct: 1351 GEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKG-- 1408

Query: 115  PAEGEGAAETLPEASRAVENGCCTPKEG----RGAPAEAGESSAPGAASSGPTSIP 166
             A+GE   E  P  +  +       K G    RG P   GE   PG  S GP   P
Sbjct: 1409 -AKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPG--SPGPDGPP 1461



 Score = 30.8 bits (68), Expect = 0.56
 Identities = 43/160 (26%), Positives = 54/160 (33%), Gaps = 23/160 (14%)

Query: 8    GPGDTSSSAAEREEDRKDGEEQEE-PRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTP 66
            GP         R +    G++ +E PRG      P       G PG K +   V     P
Sbjct: 1192 GPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPP 1251

Query: 67   KDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLP 126
              P    + PS A  +   +  P G            G+P    + G P  GE     LP
Sbjct: 1252 GPPG--PRGPSGAPGADGPQGPPGGI-----------GNPGAVGEKGEP--GEAGEPGLP 1296

Query: 127  EASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTSIP 166
                  E G   PK  RG   E+G S A G    GP   P
Sbjct: 1297 G-----EGGPPGPKGERGEKGESGPSGAAG--PPGPKGPP 1329


>gi|11560152 zinc finger protein 335 [Homo sapiens]
          Length = 1342

 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 12/116 (10%)

Query: 20  EEDRKDGEEQEEPRGKEER-QEPS-TTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPS 77
           EED      ++EPRG++ R Q P+ +T R   RPGR RK P +E  D P     +   P 
Sbjct: 318 EEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLEISDLPDG---VEGEPL 374

Query: 78  MAQDSGASELLPNGDLEKRSEPQPEEGSPAGG------QKGGAPAEGEGAAETLPE 127
           ++  SG S   P  D E  S   P      G       + G + ++ E AA + P+
Sbjct: 375 VSSQSGQSPPEPQ-DPEAPSSSGPGHLVAMGKVSRTPVEAGVSQSDAENAAPSCPD 429


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 44/163 (26%), Positives = 65/163 (39%), Gaps = 21/163 (12%)

Query: 8   GPGDTSSSAAEREEDRKDGEEQEEPRGKE---ERQEPSTTARKVGRPGRKRKHPPVESGD 64
           G G+      E EE+ K+GE +EE  G+E   ER++     +K  R G++ K    E GD
Sbjct: 736 GEGEEEEGDREEEEE-KEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGE--EEGD 792

Query: 65  TPKDPAVISKSPSMAQDSGASELLPNGDLEK----------RSEPQPEEGSPAGGQKGGA 114
             +     ++     ++ G    +  G++E+            E + EEG     +  G 
Sbjct: 793 QGEGEEEETEGRGEEKEEGGE--VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGE 850

Query: 115 PAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEA-GESSAPG 156
             EGEG  E   E     E G     EG G   E  GE    G
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEG--EEGEGEGEEEEGEGEGEEEG 891



 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 37/154 (24%), Positives = 56/154 (36%), Gaps = 19/154 (12%)

Query: 10  GDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDP 69
           G+      E EE  ++ EE++E  GKEE +       +    G ++K       +  ++ 
Sbjct: 731 GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790

Query: 70  AVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEAS 129
                      D G  E       E+ +E + EE    G  +GG   EG+G  E   E  
Sbjct: 791 G----------DQGEGE-------EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG 833

Query: 130 RA-VENGCCTPKEGRGAPAEA-GESSAPGAASSG 161
               E G    +EG G   E  G+    G    G
Sbjct: 834 EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG 867



 Score = 36.2 bits (82), Expect = 0.013
 Identities = 37/150 (24%), Positives = 50/150 (33%), Gaps = 8/150 (5%)

Query: 10   GDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKR-KHPPVESGDTPKD 68
            G+      E EE   +GEE+ E  G+EE  E        G    +  +    E G+  + 
Sbjct: 871  GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930

Query: 69   PAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAG------GQKGGAPAEGEGAA 122
                 +     +D         G+ E   E    EG   G      G+  G   EGEG  
Sbjct: 931  EGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEG 990

Query: 123  ETLPEASRAVENGCCTPK-EGRGAPAEAGE 151
            E         E G    + EG G   E GE
Sbjct: 991  EEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020



 Score = 32.3 bits (72), Expect = 0.19
 Identities = 33/137 (24%), Positives = 46/137 (33%), Gaps = 30/137 (21%)

Query: 8    GPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPK 67
            G G+      E EE+  +GE +EE  G+ E  E                      G+  +
Sbjct: 946  GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE----------------------GEGEE 983

Query: 68   DPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPE 127
            +           ++ G  E    G+ E   E + EE     G+  G   EGEG      E
Sbjct: 984  EEGEGEGEEEEGEEEGEEE--GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEG------E 1035

Query: 128  ASRAVENGCCTPKEGRG 144
                 E G    KEG G
Sbjct: 1036 EEEGEEEGEEREKEGEG 1052



 Score = 32.3 bits (72), Expect = 0.19
 Identities = 15/49 (30%), Positives = 24/49 (48%)

Query: 8    GPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRK 56
            G G+      E EE  K+GE +E  R +EE +E     ++ G    +R+
Sbjct: 1032 GEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQ 1080



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 35/135 (25%), Positives = 48/135 (35%), Gaps = 20/135 (14%)

Query: 18  EREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPS 77
           ERE+  KD    E  R  E  +E +       R G +++    E G          K  +
Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGH--------QKERN 724

Query: 78  MAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKG-GAPAEGEGAAETLPEASRAVENGC 136
              + G  E    G+ E+    + EE    G ++G G   EGE   E   E  R      
Sbjct: 725 QEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKE---EGER------ 775

Query: 137 CTPKEGRGAPAEAGE 151
              KE R    E GE
Sbjct: 776 --KKEERAGKEEKGE 788



 Score = 28.9 bits (63), Expect = 2.1
 Identities = 14/45 (31%), Positives = 22/45 (48%)

Query: 10   GDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRK 54
            G+      E EE+R++ EE+EE  GK +        R+ G   +K
Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKK 1087



 Score = 28.1 bits (61), Expect = 3.6
 Identities = 29/122 (23%), Positives = 44/122 (36%), Gaps = 7/122 (5%)

Query: 9   PGDTSSSAAERE---EDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDT 65
           P  T  + ++ E    + K+G E  +  G EE++  +         GRK K   +    T
Sbjct: 572 PATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLT 631

Query: 66  PKDPAVISKSPSMAQDSGASELLPNGDLEKRSEP----QPEEGSPAGGQKGGAPAEGEGA 121
            K      K+ S+ +     E   +G  E+ S      Q EE       KG    E  G 
Sbjct: 632 DKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE 691

Query: 122 AE 123
            E
Sbjct: 692 GE 693


>gi|194272140 dendrin [Homo sapiens]
          Length = 711

 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 38/153 (24%), Positives = 58/153 (37%), Gaps = 14/153 (9%)

Query: 28  EQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGASEL 87
           EQE+ +   + +E   T RK  + G  R+ PP      P++   +++   +        L
Sbjct: 109 EQEKRKAASQEREAKETERKRRKAGGARRSPPGRPRPEPRNAPRVAQLAGLPAPLRPERL 168

Query: 88  LPNGDLEKRS-EPQPEEGS----PAGGQKGGAPAEG-----EGAAETLPEASRAVENGCC 137
            P G   + S +PQ + GS    P GG++ G P+        G+A T P           
Sbjct: 169 APVGRAPRPSAQPQSDPGSAWAGPWGGRRPGPPSYEAHLLLRGSAGTAPRRRWDRPPPYV 228

Query: 138 TPKEGRGAPAEAGESSAPG----AASSGPTSIP 166
            P    G     G    PG      SS P + P
Sbjct: 229 APPSYEGPHRTLGTKRGPGNSQVPTSSAPAATP 261


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 36/108 (33%), Positives = 51/108 (47%), Gaps = 19/108 (17%)

Query: 18  EREEDRKDGEEQEEPRGKEERQEPST-TARKVGRPGRKRKHPPVESGDTPKDPAVISKSP 76
           +R + +KD +E +EP+ K+E +EP T  A K+ +  +++K        TPK P    KS 
Sbjct: 645 KRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTA----TPK-PKSSKKSS 699

Query: 77  SMAQDSGASEL-----------LPNGDLEKR--SEPQPEEGSPAGGQK 111
           +   DS AS L             N DL+K     P PEE    G QK
Sbjct: 700 NKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEEDEDPGVQK 747



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 10/100 (10%)

Query: 11   DTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPA 70
            +  + AA+ + + K+ EE+ +  GKE +QE    A  V     K +   VE G      +
Sbjct: 2177 EPENPAAKEKCEGKEEEEETDGSGKESKQECEAEASSV-----KNELKGVEVGADTGSKS 2231

Query: 71   VISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQ 110
            +  K      +    E L + D  + S  QPE G+ + G+
Sbjct: 2232 ISEK----GSEEDEEEKLEDDDKSEESS-QPEAGAVSRGK 2266


>gi|14993776 skeletal myosin light chain kinase [Homo sapiens]
          Length = 596

 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 36/132 (27%), Positives = 52/132 (39%), Gaps = 15/132 (11%)

Query: 39  QEPSTTARKVGRPGRKRKHPPVESGDTP--KDPAVISKSPSMAQDSGASELLPNGDLEKR 96
           Q PST     G  G +    P+ +G  P   DP      P++ +D+ A      GD    
Sbjct: 13  QNPSTDKAPKGPTGER----PLAAGKDPGPPDPKKAPDPPTLKKDAKAPAS-EKGDGTLA 67

Query: 97  SEPQPEEGSPAGGQKGGAPAEGE-GAAETLPEASRAVENGCCTPKEGRGAPA-------E 148
                 +G    G +GG PAEG  G    LP+ +   E     PK  +GA          
Sbjct: 68  QPSTSSQGPKGEGDRGGGPAEGSAGPPAALPQQTATPETSVKKPKAEQGASGSQDPGKPR 127

Query: 149 AGESSAPGAASS 160
            G+ +A G A++
Sbjct: 128 VGKKAAEGQAAA 139


>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
          Length = 871

 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 18/111 (16%)

Query: 7   SGPGDTSSSAAEREEDRKDGEEQEEPRG-------------KEERQEPSTTARKVGRPGR 53
           +G GD      +++E ++DG++ E                 KEE++E S    K     R
Sbjct: 293 AGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKR 352

Query: 54  KRKHPPVESGDTPKDPAVISKSPSMAQDSGASELLPNGD-LEKRSEPQPEE 103
            RKH    SGD   D   +S+S S ++   A E     + L+++ +P+ EE
Sbjct: 353 NRKH----SGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEE 399


>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
          Length = 875

 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 18/111 (16%)

Query: 7   SGPGDTSSSAAEREEDRKDGEEQEEPRG-------------KEERQEPSTTARKVGRPGR 53
           +G GD      +++E ++DG++ E                 KEE++E S    K     R
Sbjct: 293 AGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKR 352

Query: 54  KRKHPPVESGDTPKDPAVISKSPSMAQDSGASELLPNGD-LEKRSEPQPEE 103
            RKH    SGD   D   +S+S S ++   A E     + L+++ +P+ EE
Sbjct: 353 NRKH----SGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEE 399


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 38/155 (24%), Positives = 59/155 (38%), Gaps = 12/155 (7%)

Query: 10   GDTSSSAAEREEDRKDGEEQEEPRG---KEERQEPSTTARKVGRPGRKRKHPPVESGDTP 66
            G+    +   E    +GE Q E  G    E  +E       V  P  + +  P   G+T 
Sbjct: 2187 GEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQ 2246

Query: 67   KDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLP 126
             +      SP ++   G SE     +  + S P PE+        GG        ++T P
Sbjct: 2247 GEK---KGSPQVSLGDGQSE-----EASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGP 2298

Query: 127  EASRAVENGCCTPKEGRGAPAEAGESSAPGAASSG 161
             +SRA   G C  K+        G++ +P A S+G
Sbjct: 2299 SSSRASSWGNCWQKDSENDHV-LGDTRSPDAKSTG 2332



 Score = 34.3 bits (77), Expect = 0.050
 Identities = 43/175 (24%), Positives = 68/175 (38%), Gaps = 21/175 (12%)

Query: 3    AMPSSGPGDTSSSAAEREEDRKDGEEQEEPRG---KEERQEPSTTARKVGRPGRKRKHPP 59
            A  + G     S   E ++   +GE Q E  G   +E  +E       V  P  + +  P
Sbjct: 2134 APEAEGEAQPESEGVEAQD--AEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQP 2191

Query: 60   VESG-DTPK-----DPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGG 113
               G + P+      P +       A++    E       E   E QPE      G+K G
Sbjct: 2192 ESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKG 2251

Query: 114  AP--AEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGES--SAPGAASSGPTS 164
            +P  + G+G +E   E+S  V     TP      P+  G++    PG + +GP+S
Sbjct: 2252 SPQVSLGDGQSEEASESSSPVPEDRPTP-----PPSPGGDTPHQRPG-SQTGPSS 2300



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 30/107 (28%), Positives = 41/107 (38%), Gaps = 9/107 (8%)

Query: 20   EEDRKDGEEQEE---PRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSP 76
            EE    G+E  E   P GK  +++      + GR     +  P E  + P +P     S 
Sbjct: 1401 EEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEP----PSH 1456

Query: 77   SMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAE 123
                D  ASE      LE   E  P  G+   GQ+       +GAAE
Sbjct: 1457 LSETDPSASERQSGSQLEPGLEKPP--GATMMGQEHTQAQPTQGAAE 1501



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 39/167 (23%), Positives = 60/167 (35%), Gaps = 11/167 (6%)

Query: 9    PGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGR-PGRKRK-----HPPVES 62
            P      A E E + ++ EE+ +P       +P +   +     G  +K      P  + 
Sbjct: 1995 PESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDG 2054

Query: 63   GDTPKDPAVISKSPSMAQDSGASELLPNGDL---EKRSEPQPE-EGSPAGGQKGGAP-AE 117
             + P+      ++    Q++       + D+   E   E QPE EG  A   +G A  AE
Sbjct: 2055 VEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE 2114

Query: 118  GEGAAETLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGPTS 164
            G  A ET  EA    E       EG   P   G  +      + P S
Sbjct: 2115 GIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPES 2161



 Score = 30.8 bits (68), Expect = 0.56
 Identities = 38/158 (24%), Positives = 56/158 (35%), Gaps = 17/158 (10%)

Query: 11   DTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKV------GRPGRKRKHPPVESGD 64
            +T  +  E +++ +   E+ E  G E  QE      +V      G  G   +    E G 
Sbjct: 1340 ETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEG- 1398

Query: 65   TPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGA-PAEGEGAAE 123
             P++ +V  +  S A         P+G   +  +P  EE   AG     A P   EG  E
Sbjct: 1399 LPEEGSVHGQELSEASS-------PDGKGSQEDDPVQEE--EAGRASASAEPCPAEGTEE 1449

Query: 124  TLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSG 161
                 S   E      +   G+  E G    PGA   G
Sbjct: 1450 PTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMG 1487



 Score = 28.1 bits (61), Expect = 3.6
 Identities = 36/122 (29%), Positives = 43/122 (35%), Gaps = 23/122 (18%)

Query: 61  ESGDTPKDPAVISKSPS-MAQDSGASELLPNGDLEKRSEPQPEE------GSPAGG---- 109
           ++G     PA I    S     SGA+ L   G+ E R  PQP        G P  G    
Sbjct: 765 DAGSRTCSPAPIPPHTSDSCSKSGAASL---GE-EARDTPQPSSPLVLQVGRPEQGAVGP 820

Query: 110 -------QKGGAPAEGEGAAETLPEASRAVENGCCTPKEGRGAPAEAGESSAPGAASSGP 162
                  Q G  PA+ E      PEAS      C TP  GR  P     S     +S   
Sbjct: 821 HRSHCCSQPGTQPAQ-EAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQS 879

Query: 163 TS 164
           T+
Sbjct: 880 TA 881



 Score = 26.9 bits (58), Expect = 8.0
 Identities = 30/135 (22%), Positives = 50/135 (37%), Gaps = 14/135 (10%)

Query: 21   EDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQ 80
            E + + E  E P  ++E Q  + +   +   G        ES       A  +   +  Q
Sbjct: 1898 EVQPESEGAEAPEAEKEAQPETESVEALETEGEDEP----ESEGAEAQEAEEAAQEAEGQ 1953

Query: 81   DSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCCTPK 140
                SE++ + + E+ ++P+ E+      +     AEGE   E     S  VE       
Sbjct: 1954 TQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPE-----SEDVE-----AP 2003

Query: 141  EGRGAPAEAGESSAP 155
            E  G   EA E + P
Sbjct: 2004 EAEGEMQEAEEEAQP 2018


>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
           isoform 1 [Homo sapiens]
          Length = 824

 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 44/170 (25%), Positives = 64/170 (37%), Gaps = 29/170 (17%)

Query: 18  EREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPS 77
           E E+D  + EE+EE  G  E QE      +   PG     P VE     + P  +  +  
Sbjct: 88  EEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHR-PTTLRLTTL 146

Query: 78  MAQDS----GASELLPNGDLEKRS--EPQPE------------EGSPAGGQ--------- 110
            AQDS    G  +L+     ++ +   P PE            +  P G Q         
Sbjct: 147 GAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDC 206

Query: 111 KGGAPAEGEGAAETLPEASRAVENGCCTPKE-GRGAPAEAGESSAPGAAS 159
           +G  PAE      T P +   +E    +    GRG    + E S+PG+ S
Sbjct: 207 EGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDS 256



 Score = 27.7 bits (60), Expect = 4.7
 Identities = 11/23 (47%), Positives = 15/23 (65%)

Query: 9   PGDTSSSAAEREEDRKDGEEQEE 31
           PG   S+A   EED +D EE+E+
Sbjct: 459 PGRACSAACSEEEDEEDDEEEED 481


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.298    0.122    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,440,537
Number of Sequences: 37866
Number of extensions: 600669
Number of successful extensions: 6220
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 344
Number of HSP's successfully gapped in prelim test: 853
Number of HSP's that attempted gapping in prelim test: 3826
Number of HSP's gapped (non-prelim): 2657
length of query: 166
length of database: 18,247,518
effective HSP length: 95
effective length of query: 71
effective length of database: 14,650,248
effective search space: 1040167608
effective search space used: 1040167608
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.9 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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