Guide to the Human Genome
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Search of human proteins with 28559023

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor
[Homo sapiens]
         (333 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [H...   682   0.0  
gi|28559029 interleukin 5 receptor, alpha isoform 2 precursor [H...   682   0.0  
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H...   681   0.0  
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H...   681   0.0  
gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [H...   681   0.0  
gi|28559031 interleukin 5 receptor, alpha isoform 3 precursor [H...   681   0.0  
gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo sap...   107   1e-23
gi|20070195 colony stimulating factor 2 receptor alpha chain iso...    82   5e-16
gi|238908519 colony stimulating factor 2 receptor alpha chain is...    82   5e-16
gi|238908517 colony stimulating factor 2 receptor alpha chain is...    82   5e-16
gi|238908515 colony stimulating factor 2 receptor alpha chain is...    82   5e-16
gi|27437036 colony stimulating factor 2 receptor alpha chain iso...    82   5e-16
gi|27437032 colony stimulating factor 2 receptor alpha chain iso...    82   5e-16
gi|27437034 colony stimulating factor 2 receptor alpha chain iso...    81   1e-15
gi|238908521 colony stimulating factor 2 receptor alpha chain is...    80   2e-15
gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo sapi...    79   6e-15
gi|13324710 interleukin 3 receptor, alpha precursor [Homo sapiens]     65   8e-11
gi|27437040 colony stimulating factor 2 receptor alpha chain iso...    49   8e-06
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]      40   0.004
gi|4885491 myeloproliferative leukemia virus oncogene precursor ...    40   0.004
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]              40   0.004
gi|51093381 leptin receptor isoform 3 [Homo sapiens]                   39   0.006
gi|51093379 leptin receptor isoform 2 [Homo sapiens]                   39   0.006
gi|40254464 leptin receptor isoform 1 [Homo sapiens]                   39   0.006
gi|4506107 prolactin receptor [Homo sapiens]                           39   0.006
gi|115430248 gp130-like monocyte receptor [Homo sapiens]               36   0.042
gi|4559408 colony stimulating factor 2 receptor, beta precursor ...    35   0.093
gi|31083174 interleukin 21 receptor precursor [Homo sapiens]           35   0.093
gi|11141869 interleukin 21 receptor precursor [Homo sapiens]           35   0.093
gi|31083180 interleukin 21 receptor precursor [Homo sapiens]           35   0.093

>gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [Homo
           sapiens]
          Length = 333

 Score =  682 bits (1761), Expect = 0.0
 Identities = 333/333 (100%), Positives = 333/333 (100%)

Query: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
           MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60

Query: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
           VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120

Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
           PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180

Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
           ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240

Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
           PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300

Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK 333
           LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK 333


>gi|28559029 interleukin 5 receptor, alpha isoform 2 precursor [Homo
           sapiens]
          Length = 333

 Score =  682 bits (1761), Expect = 0.0
 Identities = 333/333 (100%), Positives = 333/333 (100%)

Query: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
           MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60

Query: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
           VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120

Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
           PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180

Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
           ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240

Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
           PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300

Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK 333
           LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK 333


>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
           sapiens]
          Length = 420

 Score =  681 bits (1756), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
           MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60

Query: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
           VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120

Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
           PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180

Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
           ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240

Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
           PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300

Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
           LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332


>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
           sapiens]
          Length = 420

 Score =  681 bits (1756), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
           MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60

Query: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
           VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120

Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
           PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180

Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
           ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240

Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
           PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300

Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
           LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332


>gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [Homo
           sapiens]
          Length = 335

 Score =  681 bits (1756), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
           MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60

Query: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
           VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120

Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
           PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180

Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
           ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240

Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
           PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300

Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
           LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332


>gi|28559031 interleukin 5 receptor, alpha isoform 3 precursor [Homo
           sapiens]
          Length = 335

 Score =  681 bits (1756), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60
           MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN
Sbjct: 1   MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRN 60

Query: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120
           VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA
Sbjct: 61  VNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHA 120

Query: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
           PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE
Sbjct: 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180

Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
           ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN
Sbjct: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240

Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
           PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD
Sbjct: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300

Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332
           LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG
Sbjct: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQPIYVG 332


>gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo
           sapiens]
          Length = 380

 Score =  107 bits (267), Expect = 1e-23
 Identities = 87/314 (27%), Positives = 142/314 (45%), Gaps = 26/314 (8%)

Query: 25  DEKISLLPPVNFTIKVTG-LAQVLLQWKPNPDQEQ-RNVNLEYQVKINAPKEDDYETRIT 82
           D +I + PP +F I   G L  + LQW+P    +  +   +EY++K      + ++T IT
Sbjct: 27  DTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIIT 86

Query: 83  ES---KCVTILHKGFSASVRTILQ---NDHSLLASSWASAELH-APPGSPGTSIVNLTCT 135
           ++   K    L+KG  A + T+L     + S + SSWA      +P G P T + ++ C 
Sbjct: 87  KNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCV 146

Query: 136 TNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRN 193
               +            L C+W  G     DT Y L+Y Y       +C +Y K   G+N
Sbjct: 147 YYNWQ-----------YLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKAD-GQN 194

Query: 194 IACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGT- 252
           I C FP  ++ +       + VNGSS++  IR     F L  I +  PP+ +T   E + 
Sbjct: 195 IGCRFP--YLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSC 252

Query: 253 RLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAV 312
            + ++W  P+   P  CFDYE++I       +          +   ++  +    VR+ V
Sbjct: 253 EIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKV 312

Query: 313 SSMCREAGLWSEWS 326
           +  C + G+WSEWS
Sbjct: 313 NIYCSDDGIWSEWS 326


>gi|20070195 colony stimulating factor 2 receptor alpha chain
           isoform a precursor [Homo sapiens]
          Length = 400

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 82/310 (26%), Positives = 128/310 (41%), Gaps = 68/310 (21%)

Query: 57  EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
           + R +NL +  + N           K    E R++ ++C        LH+G  F   V T
Sbjct: 41  DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100

Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
             +     L        L+   G  GT+  N +C     +            ++CTW  G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141

Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
             AP D QYFLY R      E  C  Y +D+ G ++ C       L+  R++   LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197

Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
           S+   I+ FD L     I++ NPP NVT     T   ++W++P +   +    F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257

Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
           H  NT+ G         N  I++  DL            +K+ V++RAA   +      W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306

Query: 323 SEWSQPIYVG 332
           S WS+ I  G
Sbjct: 307 SSWSEAIEFG 316


>gi|238908519 colony stimulating factor 2 receptor alpha chain
           isoform g precursor [Homo sapiens]
          Length = 410

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 82/310 (26%), Positives = 128/310 (41%), Gaps = 68/310 (21%)

Query: 57  EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
           + R +NL +  + N           K    E R++ ++C        LH+G  F   V T
Sbjct: 41  DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100

Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
             +     L        L+   G  GT+  N +C     +            ++CTW  G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141

Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
             AP D QYFLY R      E  C  Y +D+ G ++ C       L+  R++   LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197

Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
           S+   I+ FD L     I++ NPP NVT     T   ++W++P +   +    F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257

Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
           H  NT+ G         N  I++  DL            +K+ V++RAA   +      W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306

Query: 323 SEWSQPIYVG 332
           S WS+ I  G
Sbjct: 307 SSWSEAIEFG 316


>gi|238908517 colony stimulating factor 2 receptor alpha chain
           isoform f precursor [Homo sapiens]
          Length = 434

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 82/310 (26%), Positives = 128/310 (41%), Gaps = 68/310 (21%)

Query: 57  EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
           + R +NL +  + N           K    E R++ ++C        LH+G  F   V T
Sbjct: 41  DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100

Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
             +     L        L+   G  GT+  N +C     +            ++CTW  G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141

Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
             AP D QYFLY R      E  C  Y +D+ G ++ C       L+  R++   LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197

Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
           S+   I+ FD L     I++ NPP NVT     T   ++W++P +   +    F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257

Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
           H  NT+ G         N  I++  DL            +K+ V++RAA   +      W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306

Query: 323 SEWSQPIYVG 332
           S WS+ I  G
Sbjct: 307 SSWSEAIEFG 316


>gi|238908515 colony stimulating factor 2 receptor alpha chain
           isoform a precursor [Homo sapiens]
          Length = 400

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 82/310 (26%), Positives = 128/310 (41%), Gaps = 68/310 (21%)

Query: 57  EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
           + R +NL +  + N           K    E R++ ++C        LH+G  F   V T
Sbjct: 41  DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100

Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
             +     L        L+   G  GT+  N +C     +            ++CTW  G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141

Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
             AP D QYFLY R      E  C  Y +D+ G ++ C       L+  R++   LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197

Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
           S+   I+ FD L     I++ NPP NVT     T   ++W++P +   +    F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257

Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
           H  NT+ G         N  I++  DL            +K+ V++RAA   +      W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306

Query: 323 SEWSQPIYVG 332
           S WS+ I  G
Sbjct: 307 SSWSEAIEFG 316


>gi|27437036 colony stimulating factor 2 receptor alpha chain
           isoform c precursor [Homo sapiens]
          Length = 333

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 82/310 (26%), Positives = 128/310 (41%), Gaps = 68/310 (21%)

Query: 57  EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
           + R +NL +  + N           K    E R++ ++C        LH+G  F   V T
Sbjct: 41  DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100

Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
             +     L        L+   G  GT+  N +C     +            ++CTW  G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141

Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
             AP D QYFLY R      E  C  Y +D+ G ++ C       L+  R++   LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197

Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
           S+   I+ FD L     I++ NPP NVT     T   ++W++P +   +    F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257

Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
           H  NT+ G         N  I++  DL            +K+ V++RAA   +      W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306

Query: 323 SEWSQPIYVG 332
           S WS+ I  G
Sbjct: 307 SSWSEAIEFG 316


>gi|27437032 colony stimulating factor 2 receptor alpha chain
           isoform a precursor [Homo sapiens]
          Length = 400

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 82/310 (26%), Positives = 128/310 (41%), Gaps = 68/310 (21%)

Query: 57  EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
           + R +NL +  + N           K    E R++ ++C        LH+G  F   V T
Sbjct: 41  DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100

Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
             +     L        L+   G  GT+  N +C     +            ++CTW  G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141

Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
             AP D QYFLY R      E  C  Y +D+ G ++ C       L+  R++   LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197

Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
           S+   I+ FD L     I++ NPP NVT     T   ++W++P +   +    F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257

Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
           H  NT+ G         N  I++  DL            +K+ V++RAA   +      W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306

Query: 323 SEWSQPIYVG 332
           S WS+ I  G
Sbjct: 307 SSWSEAIEFG 316


>gi|27437034 colony stimulating factor 2 receptor alpha chain
           isoform b precursor [Homo sapiens]
          Length = 377

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 81/307 (26%), Positives = 127/307 (41%), Gaps = 68/307 (22%)

Query: 57  EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
           + R +NL +  + N           K    E R++ ++C        LH+G  F   V T
Sbjct: 41  DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100

Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
             +     L        L+   G  GT+  N +C     +            ++CTW  G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141

Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
             AP D QYFLY R      E  C  Y +D+ G ++ C       L+  R++   LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNYF--LVNGT 197

Query: 219 SKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC--FDYEVKI 276
           S+   I+ FD L     I++ NPP NVT     T   ++W++P +   +    F Y++ +
Sbjct: 198 SREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDV 257

Query: 277 H--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSSMCREAGLW 322
           H  NT+ G         N  I++  DL            +K+ V++RAA   +      W
Sbjct: 258 HRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILN----W 306

Query: 323 SEWSQPI 329
           S WS+ I
Sbjct: 307 SSWSEAI 313


>gi|238908521 colony stimulating factor 2 receptor alpha chain
           isoform h [Homo sapiens]
          Length = 267

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 61/198 (30%), Positives = 93/198 (46%), Gaps = 33/198 (16%)

Query: 153 LHCTWLVGTDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDW 210
           ++CTW  G  AP D QYFLY R      E  C  Y +D+ G ++ C       L+  R++
Sbjct: 1   MNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLTS-RNY 58

Query: 211 LAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHC- 269
              LVNG+S+   I+ FD L     I++ NPP NVT     T   ++W++P +   +   
Sbjct: 59  F--LVNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYL 116

Query: 270 -FDYEVKIH--NTRNGYLQIEKLMTNAFISIIDDL------------SKYDVQVRAAVSS 314
            F Y++ +H  NT+ G         N  I++  DL            +K+ V++RAA   
Sbjct: 117 DFQYQLDVHRKNTQPG-------TENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVR 169

Query: 315 MCREAGLWSEWSQPIYVG 332
           +      WS WS+ I  G
Sbjct: 170 ILN----WSSWSEAIEFG 183


>gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo
           sapiens]
          Length = 427

 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 36/322 (11%)

Query: 32  PPV-NFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDDYETRITESKCVTIL 90
           PPV N ++ V  L  V+  W P P+    N +L Y       K+D      T       L
Sbjct: 33  PPVTNLSVSVENLCTVIWTWNP-PEGASSNCSLWYFSHFG-DKQDKKIAPETRRSIEVPL 90

Query: 91  HKGFSASVRTILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQ 150
           ++     V +    + S   S      +  P G P +++  L C  +          SY 
Sbjct: 91  NERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNL--------SY- 141

Query: 151 VSLHCTWLVGTDAPEDTQYFLYYRYGSWTE--ECQEYSKDTLGRNIACWFPRTFILSKGR 208
             + C+WL G +   DT Y LYY + S  +  +C+   ++  G+   C F  T +     
Sbjct: 142 --MKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFRE--GQYFGCSFDLTKVKDSSF 197

Query: 209 DWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIH 268
           +  +V +        I+P   +  L +  + +PP           L +QWE P + F   
Sbjct: 198 EQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQN-FISR 256

Query: 269 CFDYEVKIHNTRNG-----YLQIEKLMTNAFISIIDDLSKY-----------DVQVRAAV 312
           C  YEV+++N++       Y+Q  K     F   +++ S +            V++R   
Sbjct: 257 CLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKT 316

Query: 313 SSMCREAG-LWSEWSQPIYVGK 333
           + +C E   LWS WSQ + +GK
Sbjct: 317 NKLCYEDDKLWSNWSQEMSIGK 338


>gi|13324710 interleukin 3 receptor, alpha precursor [Homo sapiens]
          Length = 378

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 61/208 (29%), Positives = 82/208 (39%), Gaps = 22/208 (10%)

Query: 123 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE-- 180
           G P     NLTC  +  +            L C+W VG  AP D QY LY    +  +  
Sbjct: 101 GKPWAGAENLTCWIHDVD-----------FLSCSWAVGPGAPADVQYDLYLNVANRRQQY 149

Query: 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
           EC  Y  D  G  I C F     LS G     +LV G S    I   D+      I+ + 
Sbjct: 150 ECLHYKTDAQGTRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILT 209

Query: 241 PPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDD 300
           PP N+TA+   T   + W K  S F    F YE++I       +  E++       +++ 
Sbjct: 210 PP-NMTAKCNKTHSFMHW-KMRSHFN-RKFRYELQIQKRMQPVI-TEQVRDRTSFQLLNP 265

Query: 301 LSKYDVQVRAAVSSMCREAGLWSEWSQP 328
              Y VQ+RA      R     S WS P
Sbjct: 266 -GTYTVQIRARE----RVYEFLSAWSTP 288


>gi|27437040 colony stimulating factor 2 receptor alpha chain
           isoform e precursor [Homo sapiens]
          Length = 233

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 51/192 (26%), Positives = 77/192 (40%), Gaps = 41/192 (21%)

Query: 57  EQRNVNLEYQVKINAP---------KEDDYETRITESKCVTI-----LHKG--FSASVRT 100
           + R +NL +  + N           K    E R++ ++C        LH+G  F   V T
Sbjct: 41  DSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNT 100

Query: 101 ILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVG 160
             +     L        L+   G  GT+  N +C     +            ++CTW  G
Sbjct: 101 SQRGFQQKL--------LYPNSGREGTAAQNFSCFIYNAD-----------LMNCTWARG 141

Query: 161 TDAPEDTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGS 218
             AP D QYFLY R      E  C  Y +D+ G ++ C       L+  R++   LVNG+
Sbjct: 142 PTAPRDVQYFLYIRNSKRRREIRCPYYIQDS-GTHVGCHLDNLSGLT-SRNYF--LVNGT 197

Query: 219 SKHSAIRPFDQL 230
           S+   I+ FD L
Sbjct: 198 SREIGIQFFDSL 209


>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
          Length = 369

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 42/186 (22%), Positives = 77/186 (41%), Gaps = 14/186 (7%)

Query: 153 LHCTWLVGTDAPEDTQYFLYYRY-GSWTEECQEYSKDTLGRNIA--CWFPRTFILSKGRD 209
           ++CTW   ++ P+ T   L+Y Y  S  ++ Q+ S       I   C   +  I      
Sbjct: 70  MNCTWNSSSE-PQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI----HL 124

Query: 210 WLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTA-EIEGTRLSIQWEKPVSAFPIH 268
           +   +V         R   Q+  L  +     P N+T  ++  ++L + W    + F  H
Sbjct: 125 YQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNH 181

Query: 269 CFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWSEWS 326
           C ++ V+     +     + +      S+  +D   +Y  +VR+  + +C  A  WSEWS
Sbjct: 182 CLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWS 241

Query: 327 QPIYVG 332
            PI+ G
Sbjct: 242 HPIHWG 247


>gi|4885491 myeloproliferative leukemia virus oncogene precursor
           [Homo sapiens]
          Length = 635

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 65/300 (21%), Positives = 107/300 (35%), Gaps = 40/300 (13%)

Query: 44  AQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQ 103
           AQ  + W+  P Q   +            +E    T    S  ++ L  G S  ++   +
Sbjct: 212 AQPTMPWQDGPKQTSPS------------REASALTAEGGSCLISGLQPGNSYWLQLRSE 259

Query: 104 NDHSLLASSWASAELHAPPGSPGTSI-VNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTD 162
            D   L  SW S  L      PG ++ + L C T   ++           + C W     
Sbjct: 260 PDGISLGGSWGSWSLPVTVDLPGDAVALGLQCFTLDLKN-----------VTCQWQQQDH 308

Query: 163 APEDTQYFLYY---------RYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLAV 213
           A   +Q F Y+         RY  W E C+E  K   G      F R    S+    + +
Sbjct: 309 A--SSQGFFYHSRARCCPRDRYPIW-ENCEEEEKTNPGLQTP-QFSRCHFKSRNDSIIHI 364

Query: 214 LVNGSSKHSAIRPF-DQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVS-AFPIHCFD 271
           LV  ++    +  +    F +H   ++  P     EI    L ++W+ P S A    C+ 
Sbjct: 365 LVEVTTAPGTVHSYLGSPFWIHQAVRLPTPNLHWREISSGHLELEWQHPSSWAAQETCYQ 424

Query: 272 YEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYV 331
                   ++  +    L        +   S+Y +Q+RA ++    + G WS WS P  V
Sbjct: 425 LRYTGEGHQDWKVLEPPLGARGGTLELRPRSRYRLQLRARLNGPTYQ-GPWSSWSDPTRV 483


>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
          Length = 422

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 61/248 (24%), Positives = 98/248 (39%), Gaps = 58/248 (23%)

Query: 105 DHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAP 164
           D S+LA S     L  PP  P    VN++C +   +D           L C W  G    
Sbjct: 120 DGSILAGSCLYVGL--PPEKP----VNISCWSKNMKD-----------LTCRWTPGAHGE 162

Query: 165 E--DTQYFLYYRYGSWTEE--CQEYSKDTLGRNIACWFPRTFILSKGRD-WLAVLVNGSS 219
               T Y L Y+   + ++  C+EY   T+G + +C  P+   L    + W+       S
Sbjct: 163 TFLHTNYSLKYKLRWYGQDNTCEEYH--TVGPH-SCHIPKDLALFTPYEIWVEATNRLGS 219

Query: 220 KHSAIRPFDQLFALHAIDQINPPLNVTAEIEG---TRLSIQWEKPVSAFPIHCFDYEVKI 276
             S +   D L  +      +PP +V     G    +LS++W  P +   +  F ++ K 
Sbjct: 220 ARSDVLTLDILDVVTT----DPPPDVHVSRVGGLEDQLSVRWVSPPA---LKDFLFQAK- 271

Query: 277 HNTRNGYLQIEKLMTNAFISIIDDLSK--------------YDVQVRAAVSSM--CREAG 320
                 Y    ++  +    ++DD+S               Y VQVR     +   ++AG
Sbjct: 272 ------YQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAG 325

Query: 321 LWSEWSQP 328
           +WSEWS P
Sbjct: 326 IWSEWSHP 333


>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
          Length = 958

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 11/94 (11%)

Query: 240 NPPLNVTAEI-EGTRLSIQWEKP-VSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISI 297
           +PPL +  EI +   L I W  P +  FP+    Y+VK        ++    + +A   +
Sbjct: 238 DPPLGLHMEITDDGNLKISWSSPPLVPFPLQ---YQVKYSENSTTVIREADKIVSATSLL 294

Query: 298 IDDL---SKYDVQVRAAVSSMCREAGLWSEWSQP 328
           +D +   S Y+VQVR          G+WS+WS P
Sbjct: 295 VDSILPGSSYEVQVRG---KRLDGPGIWSDWSTP 325



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 52/221 (23%), Positives = 81/221 (36%), Gaps = 42/221 (19%)

Query: 130 VNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGT--DAPEDTQYFLYYRYGSWTEECQEYS- 186
           +N++C T+           Y   + C W   T     E T    Y+R   +  +      
Sbjct: 432 INISCETD----------GYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHP 481

Query: 187 ----KDTLGRN---IACWFPRTFILSKGRDWLAV---LVNGSSKHSAIRPFDQLFALHAI 236
               KD   ++     C F   F+LS    W+ +   L +  S  + + P   +  L   
Sbjct: 482 ISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPL--- 538

Query: 237 DQINPPLNVTAEIEGT--RLSIQWEKPVSAFPIHCFDYEVKIHNTRNG-----YLQIEKL 289
               PP +V AEI      L I WEKPV  FP +   ++++   +        Y   +  
Sbjct: 539 ----PPSSVKAEITINIGLLKISWEKPV--FPENNLQFQIRYGLSGKEVQWKMYEVYDAK 592

Query: 290 MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIY 330
             +  + + D  + Y VQVR          G WS WS P Y
Sbjct: 593 SKSVSLPVPDLCAVYAVQVRC---KRLDGLGYWSNWSNPAY 630


>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
          Length = 896

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 11/94 (11%)

Query: 240 NPPLNVTAEI-EGTRLSIQWEKP-VSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISI 297
           +PPL +  EI +   L I W  P +  FP+    Y+VK        ++    + +A   +
Sbjct: 238 DPPLGLHMEITDDGNLKISWSSPPLVPFPLQ---YQVKYSENSTTVIREADKIVSATSLL 294

Query: 298 IDDL---SKYDVQVRAAVSSMCREAGLWSEWSQP 328
           +D +   S Y+VQVR          G+WS+WS P
Sbjct: 295 VDSILPGSSYEVQVRG---KRLDGPGIWSDWSTP 325



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 52/221 (23%), Positives = 81/221 (36%), Gaps = 42/221 (19%)

Query: 130 VNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGT--DAPEDTQYFLYYRYGSWTEECQEYS- 186
           +N++C T+           Y   + C W   T     E T    Y+R   +  +      
Sbjct: 432 INISCETD----------GYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHP 481

Query: 187 ----KDTLGRN---IACWFPRTFILSKGRDWLAV---LVNGSSKHSAIRPFDQLFALHAI 236
               KD   ++     C F   F+LS    W+ +   L +  S  + + P   +  L   
Sbjct: 482 ISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPL--- 538

Query: 237 DQINPPLNVTAEIEGT--RLSIQWEKPVSAFPIHCFDYEVKIHNTRNG-----YLQIEKL 289
               PP +V AEI      L I WEKPV  FP +   ++++   +        Y   +  
Sbjct: 539 ----PPSSVKAEITINIGLLKISWEKPV--FPENNLQFQIRYGLSGKEVQWKMYEVYDAK 592

Query: 290 MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIY 330
             +  + + D  + Y VQVR          G WS WS P Y
Sbjct: 593 SKSVSLPVPDLCAVYAVQVRC---KRLDGLGYWSNWSNPAY 630


>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
          Length = 1165

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 11/94 (11%)

Query: 240 NPPLNVTAEI-EGTRLSIQWEKP-VSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISI 297
           +PPL +  EI +   L I W  P +  FP+    Y+VK        ++    + +A   +
Sbjct: 238 DPPLGLHMEITDDGNLKISWSSPPLVPFPLQ---YQVKYSENSTTVIREADKIVSATSLL 294

Query: 298 IDDL---SKYDVQVRAAVSSMCREAGLWSEWSQP 328
           +D +   S Y+VQVR          G+WS+WS P
Sbjct: 295 VDSILPGSSYEVQVRG---KRLDGPGIWSDWSTP 325



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 52/221 (23%), Positives = 81/221 (36%), Gaps = 42/221 (19%)

Query: 130 VNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGT--DAPEDTQYFLYYRYGSWTEECQEYS- 186
           +N++C T+           Y   + C W   T     E T    Y+R   +  +      
Sbjct: 432 INISCETD----------GYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHP 481

Query: 187 ----KDTLGRN---IACWFPRTFILSKGRDWLAV---LVNGSSKHSAIRPFDQLFALHAI 236
               KD   ++     C F   F+LS    W+ +   L +  S  + + P   +  L   
Sbjct: 482 ISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPL--- 538

Query: 237 DQINPPLNVTAEIEGT--RLSIQWEKPVSAFPIHCFDYEVKIHNTRNG-----YLQIEKL 289
               PP +V AEI      L I WEKPV  FP +   ++++   +        Y   +  
Sbjct: 539 ----PPSSVKAEITINIGLLKISWEKPV--FPENNLQFQIRYGLSGKEVQWKMYEVYDAK 592

Query: 290 MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIY 330
             +  + + D  + Y VQVR          G WS WS P Y
Sbjct: 593 SKSVSLPVPDLCAVYAVQVRC---KRLDGLGYWSNWSNPAY 630


>gi|4506107 prolactin receptor [Homo sapiens]
          Length = 622

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 48/190 (25%), Positives = 80/190 (42%), Gaps = 24/190 (12%)

Query: 155 CTWLVGTDAPEDTQYFL-YYRYG-SWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLA 212
           C W  GTD    T Y L Y+R G +   EC +Y   T G N +C F + +  S  R ++ 
Sbjct: 46  CWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGPN-SCHFGKQY-TSMWRTYI- 100

Query: 213 VLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTR-----LSIQWEKPV----- 262
           ++VN +++  +    +    +  I Q +PPL +  E++        L I+W  P      
Sbjct: 101 MMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLK 160

Query: 263 SAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCR-EAGL 321
           + +    ++  +K        +      T   I  +    KY VQVR      C+ + G 
Sbjct: 161 TGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVR------CKPDHGY 214

Query: 322 WSEWSQPIYV 331
           WS WS   ++
Sbjct: 215 WSAWSPATFI 224


>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
          Length = 764

 Score = 36.2 bits (82), Expect = 0.042
 Identities = 45/200 (22%), Positives = 81/200 (40%), Gaps = 22/200 (11%)

Query: 141 DNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLY--YRYGSWTEECQEYSKDTLGRNIACWF 198
           +N S +  Y+ +L CTW  G +    TQY +   Y +G   + C   S  +  R    +F
Sbjct: 58  ENISCVYYYRKNLTCTWSPGKETSY-TQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFF 116

Query: 199 -PRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAE-IEGTR--L 254
            PR  I     D   + V   +    I+     + L  I +  PP     + + G +  +
Sbjct: 117 LPRITI----PDNYTIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVLGIKRMI 172

Query: 255 SIQWEKPVSAFPIHCFDYEVKIHNTRN------GYLQIEKLMTNAF-ISIIDDLSKYDVQ 307
            I+W KP  A       Y ++     +       + +  K     + ++ +   ++Y + 
Sbjct: 173 QIEWIKPELAPVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTGLQPFTEYVIA 232

Query: 308 VRAAVSSMCREAGLWSEWSQ 327
           +R AV    +E+  WS+WSQ
Sbjct: 233 LRCAV----KESKFWSDWSQ 248


>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 35.0 bits (79), Expect = 0.093
 Identities = 41/184 (22%), Positives = 74/184 (40%), Gaps = 20/184 (10%)

Query: 153 LHCTWLVGTDAPEDTQYFLYYRYG--SWTEECQEYSKDTLGR---NIACWFPRTFILSKG 207
           L C+W V  +      + L+Y+    +  EEC    ++ LG       C  P     + G
Sbjct: 258 LSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATHG 317

Query: 208 RDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPI 267
           +  ++V    + KH        + +   I    P LNVT +  G   S++WE     +  
Sbjct: 318 QYIVSVQPRRAEKH--------IKSSVNIQMAPPSLNVTKD--GDSYSLRWETMKMRYEH 367

Query: 268 --HCFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWS 323
             H F+ + +         + E L     +++  ++  ++Y  +VR   S      G+WS
Sbjct: 368 IDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTGYN-GIWS 426

Query: 324 EWSQ 327
           EWS+
Sbjct: 427 EWSE 430


>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 35.0 bits (79), Expect = 0.093
 Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 13/101 (12%)

Query: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
           PP NVT    G + +I W    E P          YE++  N         R   + ++ 
Sbjct: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180

Query: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPI 329
              +         S Y++QVRA         G WSEWS P+
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPV 221


>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 35.0 bits (79), Expect = 0.093
 Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 13/101 (12%)

Query: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
           PP NVT    G + +I W    E P          YE++  N         R   + ++ 
Sbjct: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180

Query: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPI 329
              +         S Y++QVRA         G WSEWS P+
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPV 221


>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 35.0 bits (79), Expect = 0.093
 Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 13/101 (12%)

Query: 241 PPLNVTAEIEGTRLSIQW----EKPVSAFPIHCFDYEVKIHNT--------RNGYLQIEK 288
           PP NVT    G + +I W    E P          YE++  N         R   + ++ 
Sbjct: 122 PPFNVTVTFSG-QYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS 180

Query: 289 LMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPI 329
              +         S Y++QVRA         G WSEWS P+
Sbjct: 181 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPV 221


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,350,685
Number of Sequences: 37866
Number of extensions: 565711
Number of successful extensions: 1644
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1540
Number of HSP's gapped (non-prelim): 128
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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