Search of human proteins with 27734935

Search of human proteins with 27734935

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27734935 solute carrier family 9 (sodium/hydrogen
exchanger), member 9 [Homo sapiens]
         (645 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),...  1302   0.0  
gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger)...   765   0.0  
gi|14211919 solute carrier family 9, member 7 [Homo sapiens]          743   0.0  
gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger), ...   720   0.0  
gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]                276   4e-74
gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ...   220   4e-57
gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger)...   213   3e-55
gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger)...   200   3e-51
gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),...   199   5e-51
gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]        197   2e-50
gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]      60   6e-09
gi|224465231 solute carrier family 9, member 11 [Homo sapiens]         35   0.16 
gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo s...    32   2.4  
gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo sa...    32   2.4  
gi|166795299 solute carrier family 2 (facilitated glucose transp...    31   3.1  
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    31   4.0  
gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming ...    30   6.9  
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    30   6.9  

>gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),
           member 9 [Homo sapiens]
          Length = 645

 Score = 1302 bits (3369), Expect = 0.0
 Identities = 645/645 (100%), Positives = 645/645 (100%)

Query: 1   MERQSRVMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGL 60
           MERQSRVMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGL
Sbjct: 1   MERQSRVMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGL 60

Query: 61  IMGLILRYATAPTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQG 120
           IMGLILRYATAPTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQG
Sbjct: 61  IMGLILRYATAPTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQG 120

Query: 121 NAILEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLI 180
           NAILEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLI
Sbjct: 121 NAILEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLI 180

Query: 181 MYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGES 240
           MYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGES
Sbjct: 181 MYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGES 240

Query: 241 VLNDAVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLT 300
           VLNDAVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLT
Sbjct: 241 VLNDAVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLT 300

Query: 301 KFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIR 360
           KFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIR
Sbjct: 301 KFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIR 360

Query: 361 TKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLN 420
           TKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLN
Sbjct: 361 TKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLN 420

Query: 421 LGRKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGT 480
           LGRKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGT
Sbjct: 421 LGRKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGT 480

Query: 481 TPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPI 540
           TPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPI
Sbjct: 481 TPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPI 540

Query: 541 LTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCS 600
           LTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCS
Sbjct: 541 LTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCS 600

Query: 601 PPARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQTLGQSQLN 645
           PPARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQTLGQSQLN
Sbjct: 601 PPARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQTLGQSQLN 645


>gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger),
           member 6 isoform a [Homo sapiens]
          Length = 701

 Score =  765 bits (1975), Expect = 0.0
 Identities = 396/636 (62%), Positives = 486/636 (76%), Gaps = 19/636 (2%)

Query: 7   VMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLIL 66
           ++SEK   +   Q +  LL+F  LL LTILTIWLFK+ R RFLHETG AM+YGL++GL+L
Sbjct: 57  IVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVL 116

Query: 67  RYAT-APTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQGNAILE 125
           RY    P+D+ + T+    ++  SP+TLLVN++ + YEY  K EIS H +N  Q N +L 
Sbjct: 117 RYGIHVPSDVNNVTL--SCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLR 174

Query: 126 KMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFV 185
           K+TFDPE+FFN+LLPPIIF+AGYSLK+RHFF+NLGSIL YAFLGTAISC VIG IMYG V
Sbjct: 175 KVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCV 234

Query: 186 KAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDA 245
             M   GQL  GDF+FTDCL FG+++SATDPVTVLAIFHEL VD +LY LLFGESVLNDA
Sbjct: 235 TLMKVTGQLA-GDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDA 293

Query: 246 VAIVLTYSISIYSPK-ENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTK 304
           VAIVL+ SI  Y P  +N + FD  A F+S+G FLGIF+GSFAMG+A  ++TAL+TKFTK
Sbjct: 294 VAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTK 353

Query: 305 LCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQL 364
           L EF +LETGLFFL+SWS FL AEA G TG+VAVLFCG+TQAHYTYNNLS++S+ RTKQL
Sbjct: 354 LREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQL 413

Query: 365 FEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRK 424
           FE +NFLAEN IF YMGL LFTFQNH+FN  F++GAF+AIF+ RA NIYPLS LLNLGR+
Sbjct: 414 FELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRR 473

Query: 425 QKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPML 484
            KI  NFQHMMMF+GLRGA+AFALAIR+T +  +QMMF+TTLL+VFFTVWVFGGGTT ML
Sbjct: 474 SKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAML 533

Query: 485 TWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPILTHS 544
           + L IRVGVD D+        +H      ++  TKAESA LFRMWY+FDH YLKP+LTHS
Sbjct: 534 SCLHIRVGVDSDQ--------EHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHS 585

Query: 545 GPPLTTTLPEWCGPISRLLTSPQAY--GEQLKEDDVECIVNQDELAINYQEQASSPCSPP 602
           GPPLTTTLP  CGPI+R LTSPQAY   EQLK+DD + I+N  ++++ Y +  S+  + P
Sbjct: 586 GPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGD--STVNTEP 643

Query: 603 ARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQT 638
           A     ++    +   E+  + +L  G +EL +  T
Sbjct: 644 ATSSAPRRFMGNS--SEDALDRELAFGDHELVIRGT 677


>gi|14211919 solute carrier family 9, member 7 [Homo sapiens]
          Length = 725

 Score =  743 bits (1917), Expect = 0.0
 Identities = 393/663 (59%), Positives = 479/663 (72%), Gaps = 39/663 (5%)

Query: 9   SEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLILRY 68
           +EK+  +   Q +V LL F  LL LTILTIWLFK+ R RFLHETG AM+YGLI+G+ILRY
Sbjct: 59  TEKEAEESHRQDSVSLLTFILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRY 118

Query: 69  ATAPTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQGNAILEKMT 128
            T  T     ++  C +   + STLLVN++ + +EY  K EIS   IN  + N +L K+T
Sbjct: 119 GTPATSGRDKSL-SCTQEDRAFSTLLVNVSGKFFEYTLKGEISPGKINSVEQNDMLRKVT 177

Query: 129 FDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAM 188
           FDPE+FFN+LLPPIIFHAGYSLKKRHFF+NLGSIL YAFLGTA+SC +IG +MYG VK M
Sbjct: 178 FDPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLM 237

Query: 189 IHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAI 248
              GQL +  F++TDCLFFG+++SATDPVTVLAIF+ELH D DLY LLFGESVLNDAVAI
Sbjct: 238 KIMGQLSD-KFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAI 296

Query: 249 VLTYSISIYSPKE-NPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCE 307
           VL+ SI  Y P   N +AFDAAAFF+SVG FLGIF+GSF MG+   +  A +TKFTKL  
Sbjct: 297 VLSSSIVAYQPAGLNTHAFDAAAFFKSVGIFLGIFSGSFTMGAVTGV-NANVTKFTKLHC 355

Query: 308 FPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEF 367
           FP+LET LFFL+SWS FL AEA G TG+VAVLFCG+TQAHYTYNNLS +S+ RTKQLFE 
Sbjct: 356 FPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFEV 415

Query: 368 MNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKI 427
           ++FLAEN IF YMGLALFTFQ H+F+ +FI+GAF+AIF+ RA +IYPLSF LNLGR+ KI
Sbjct: 416 LHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHKI 475

Query: 428 PWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWL 487
            WNFQHMMMFSGLRGA+AFALAIR+T S  +QMMFTTTLL+VFFTVW+ GGGTTPML+WL
Sbjct: 476 GWNFQHMMMFSGLRGAMAFALAIRDTASYARQMMFTTTLLIVFFTVWIIGGGTTPMLSWL 535

Query: 488 QIRVGVDLDENLKEDPSSQHQE--------------------------ANNLDKNMTKAE 521
            IRVGV+  E  +ED +  H +                           ++   N TK E
Sbjct: 536 NIRVGVE--EPSEEDQNEHHWQYFRVGVDPDQDPPPNNDSFQVLQGDGPDSARGNRTKQE 593

Query: 522 SARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQ--LKEDDVE 579
           SA +FR+WYSFDH YLKPILTHSGPPLTTTLP WCG ++R LTSPQ Y  Q  L+E+D +
Sbjct: 594 SAWIFRLWYSFDHNYLKPILTHSGPPLTTTLPAWCGLLARCLTSPQVYDNQEPLREEDSD 653

Query: 580 CIVNQDELAINYQEQA----SSPCSPPARLGLDQKASPQTPGKENIYEGDLGLGGYELKL 635
            I+ + +L + Y +       S  S  A   L+     ++   E + E DLG+G  ++  
Sbjct: 654 FILTEGDLTLTYGDSTVTANGSSSSHTASTSLEGSRRTKS-SSEEVLERDLGMGDQKVSS 712

Query: 636 EQT 638
             T
Sbjct: 713 RGT 715


>gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger),
           member 6 isoform b [Homo sapiens]
          Length = 669

 Score =  720 bits (1859), Expect = 0.0
 Identities = 382/636 (60%), Positives = 466/636 (73%), Gaps = 51/636 (8%)

Query: 7   VMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLIL 66
           ++SEK   +   Q +  LL+F  LL LTILTIWLFK+ R RFLHETG AM+YGL++GL+L
Sbjct: 57  IVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVL 116

Query: 67  RYAT-APTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQGNAILE 125
           RY    P+D+ + T+    ++  SP+TLLV                              
Sbjct: 117 RYGIHVPSDVNNVTL--SCEVQSSPTTLLV------------------------------ 144

Query: 126 KMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFV 185
             TFDPE+FFN+LLPPIIF+AGYSLK+RHFF+NLGSIL YAFLGTAISC VIG IMYG V
Sbjct: 145 --TFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCV 202

Query: 186 KAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDA 245
             M   GQL  GDF+FTDCL FG+++SATDPVTVLAIFHEL VD +LY LLFGESVLNDA
Sbjct: 203 TLMKVTGQLA-GDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDA 261

Query: 246 VAIVLTYSISIYSPK-ENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTK 304
           VAIVL+ SI  Y P  +N + FD  A F+S+G FLGIF+GSFAMG+A  ++TAL+TKFTK
Sbjct: 262 VAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTK 321

Query: 305 LCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQL 364
           L EF +LETGLFFL+SWS FL AEA G TG+VAVLFCG+TQAHYTYNNLS++S+ RTKQL
Sbjct: 322 LREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQL 381

Query: 365 FEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRK 424
           FE +NFLAEN IF YMGL LFTFQNH+FN  F++GAF+AIF+ RA NIYPLS LLNLGR+
Sbjct: 382 FELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRR 441

Query: 425 QKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPML 484
            KI  NFQHMMMF+GLRGA+AFALAIR+T +  +QMMF+TTLL+VFFTVWVFGGGTT ML
Sbjct: 442 SKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAML 501

Query: 485 TWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPILTHS 544
           + L IRVGVD D+        +H      ++  TKAESA LFRMWY+FDH YLKP+LTHS
Sbjct: 502 SCLHIRVGVDSDQ--------EHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHS 553

Query: 545 GPPLTTTLPEWCGPISRLLTSPQAY--GEQLKEDDVECIVNQDELAINYQEQASSPCSPP 602
           GPPLTTTLP  CGPI+R LTSPQAY   EQLK+DD + I+N  ++++ Y +  S+  + P
Sbjct: 554 GPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGD--STVNTEP 611

Query: 603 ARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQT 638
           A     ++    +   E+  + +L  G +EL +  T
Sbjct: 612 ATSSAPRRFMGNS--SEDALDRELAFGDHELVIRGT 645


>gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]
          Length = 581

 Score =  276 bits (706), Expect = 4e-74
 Identities = 164/432 (37%), Positives = 252/432 (58%), Gaps = 22/432 (5%)

Query: 125 EKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGF 184
           E+  F P +FF +LLPPIIF +GYSL K +FFQN+GSI  +A  GTAIS  V+G  +Y  
Sbjct: 117 EEEMFRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFL 176

Query: 185 VKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLND 244
            +A + +        + TD   FGSL+SA DPV  +AIF+ LHVDP L  L+FGES+LND
Sbjct: 177 GQADVIS------KLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILND 230

Query: 245 AVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTK 304
           AV+IVLT +    + K   +      F Q++  FL +F GS A+G+   +I+AL+ K   
Sbjct: 231 AVSIVLTNTAEGLTRKNMSDVSGWQTFLQALDYFLKMFFGSAALGTLTGLISALVLKHID 290

Query: 305 LCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQL 364
           L + P LE G+  + ++  +  AE   L+GI+A+LF G+  +HYT++NLS  ++I  +Q 
Sbjct: 291 LRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQT 350

Query: 365 FEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRK 424
              + FL E  +F ++GL++F+F  H F   F++   + +   RA NI+PLS+LLN  R 
Sbjct: 351 LRTVAFLCETCVFAFLGLSIFSFP-HKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRD 409

Query: 425 QKIPWNFQHMMMFSGLRGAIAFALAIRNTESQP---KQMMFTTTLLLVFFTVWVFGGGTT 481
            KI      +M FSGLRGAI +AL++ + + +P   +Q++ TTT+++V FT+ + GG T 
Sbjct: 410 HKITPKMMFIMWFSGLRGAIPYALSL-HLDLEPMEKRQLIGTTTIVIVLFTILLLGGSTM 468

Query: 482 PMLTWLQI---------RVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARL--FRMWY 530
           P++  + I         +  V+L +  K   + + +  + L +   +A   R    + + 
Sbjct: 469 PLIRLMDIEDAKAHRRNKKDVNLSKTEKMGNTVESEHLSELTEEEYEAHYIRRQDLKGFV 528

Query: 531 SFDHKYLKPILT 542
             D KYL P  T
Sbjct: 529 WLDAKYLNPFFT 540


>gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
           isoform 5 [Homo sapiens]
          Length = 896

 Score =  220 bits (560), Expect = 4e-57
 Identities = 144/421 (34%), Positives = 222/421 (52%), Gaps = 20/421 (4%)

Query: 130 DPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMI 189
           +P  FF  LLPPI+  +GY +  R FF NLG+ILTYA +GT  +    G  ++G  +A +
Sbjct: 103 EPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGL 162

Query: 190 HAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIV 249
            A +++ G     D L FGSL+SA DPV VLA+F E+HV+  L+ ++FGES+LNDAV +V
Sbjct: 163 VAPRVQAG---LLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVV 219

Query: 250 LTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFP 309
           L    + +    + N   A  + + V +   +  G  A+G  +A + AL T+FTK     
Sbjct: 220 LYKVCNSFVEMGSANV-QATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVR-- 276

Query: 310 MLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMN 369
           ++E  L FLL+++A+L+AE A L+ I+AV  CG+    Y   N+S  S+   K   + + 
Sbjct: 277 IIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLA 336

Query: 370 FLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPW 429
             AE VIF  +G++        +++  +LG  + I   RA  +   +++LN  R   +  
Sbjct: 337 SCAETVIFMLLGISAVDSSKWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDK 396

Query: 430 NFQHMMMFSGLRGAIAFALAI--RNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWL 487
             Q +M + GLRGA+AFAL I    T+   K     TT+++VFFTV V G    P++ WL
Sbjct: 397 IDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWL 456

Query: 488 QIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESA------RLFR-MWYSFDHKYLKPI 540
           +++        L     +Q    +  D  +   E          +R  W  FD KYL  +
Sbjct: 457 KVKRSEHHKPTL-----NQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQL 511

Query: 541 L 541
           L
Sbjct: 512 L 512


>gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger),
           isoform 3 [Homo sapiens]
          Length = 834

 Score =  213 bits (543), Expect = 3e-55
 Identities = 140/430 (32%), Positives = 226/430 (52%), Gaps = 27/430 (6%)

Query: 124 LEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYG 183
           +   T  P +FF  LLPPI+  AGY +  R FF NLG+IL YA +GT  +    GL +YG
Sbjct: 105 IASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYG 164

Query: 184 -FVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVL 242
            F+  ++  G L+ G     D L FGSLM+A DPV VLA+F E+HV+  L+ ++FGES+L
Sbjct: 165 VFLSGLM--GDLQIG---LLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLL 219

Query: 243 NDAVAIVL--TYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLT 300
           NDAV +VL   +   +    +N    D     + + +F  +  G   +G  +A + +L+T
Sbjct: 220 NDAVTVVLYNVFESFVALGGDNVTGVDCV---KGIVSFFVVSLGGTLVGVVFAFLLSLVT 276

Query: 301 KFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIR 360
           +FTK     ++E G  F++S+ ++L++E   L+ I+A+ FCG+    Y   N+S  S   
Sbjct: 277 RFTK--HVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATT 334

Query: 361 TKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLN 420
            +   + +   AE +IF ++G++        +N  F+L   + I V RA  +   ++LLN
Sbjct: 335 VRYTMKMLASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLN 394

Query: 421 LGRKQKIPWNFQHMMMFSGLRGAIAFALAI--RNTESQPKQMMFTTTLLLVFFTVWVFGG 478
             R  ++    Q ++ + GLRGA+AFAL +     + + K +  +TT+++VFFTV   G 
Sbjct: 395 RYRMVQLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGL 454

Query: 479 GTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESAR-------LFRMWYS 531
              P++ WL+++     +  L E     H  A   D  ++  E          L   W  
Sbjct: 455 TIKPLVQWLKVKRSEHREPRLNE---KLHGRA--FDHILSAIEDISGQIGHNYLRDKWSH 509

Query: 532 FDHKYLKPIL 541
           FD K+L  +L
Sbjct: 510 FDRKFLSRVL 519


>gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger),
           member 4 [Homo sapiens]
          Length = 798

 Score =  200 bits (509), Expect = 3e-51
 Identities = 130/427 (30%), Positives = 218/427 (51%), Gaps = 22/427 (5%)

Query: 130 DPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMI 189
           D  I+F  LLPPI+   GY +  R FF+N+GSIL +A LG  I+ + IGL +Y  +   +
Sbjct: 126 DSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLY--LICQV 183

Query: 190 HAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIV 249
            A  L  GD +    L FGSL+SA DPV VLA+F E  V+  LY ++FGE++LND + +V
Sbjct: 184 KAFGL--GDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVV 241

Query: 250 LTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFP 309
           L   +  ++        +          F+ +  G    G  +  I+A +T+FT+     
Sbjct: 242 LYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFTQ--NIS 299

Query: 310 MLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMN 369
            +E  + F+ S+ ++L+AE   L+GI+A+  C VT   Y   N+S  S    K   + ++
Sbjct: 300 AIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLS 359

Query: 370 FLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPW 429
            ++E +IF +MG++    +NH +N  FI        + RA +++ L ++ N  R      
Sbjct: 360 SVSETLIFIFMGVST-VGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSI 418

Query: 430 NFQHMMMFSGLRGAIAFALAIRNTES--QPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWL 487
             Q ++ +SG+RGA +F+LA     S    K+M  T TL++++FTV++ G    P++ +L
Sbjct: 419 KDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYL 478

Query: 488 QIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESA-------RLFRMWYSFDHKYLKPI 540
                 D+ +  K++  ++      +D      E         ++   +  FDH+YL+ I
Sbjct: 479 ------DVKKTNKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKI 532

Query: 541 LTHSGPP 547
           L     P
Sbjct: 533 LIRKNLP 539


>gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),
           member 2 [Homo sapiens]
          Length = 812

 Score =  199 bits (507), Expect = 5e-51
 Identities = 133/425 (31%), Positives = 214/425 (50%), Gaps = 24/425 (5%)

Query: 132 EIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMIHA 191
           ++FF  LLPPI+  AGY +  R FF+N+G+I  YA +GT  + I IG+ ++G  +  I A
Sbjct: 139 DVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFGICQ--IEA 196

Query: 192 GQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLT 251
             L   D      L FGSL+SA DPV VLA+F  +HV+  LY L+FGES+LNDAV +VL 
Sbjct: 197 FGLS--DITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLY 254

Query: 252 YSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPML 311
                +   +     D    F  + NF  +  G   +G     I A  T+FT      ++
Sbjct: 255 NLFKSFCQMKTIETIDV---FAGIANFFVVGIGGVLIGIFLGFIAAFTTRFTH--NIRVI 309

Query: 312 ETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFL 371
           E    FL S+ ++++AE   L+GI+A+  C +T   Y   N+S  S    K   + ++ +
Sbjct: 310 EPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSV 369

Query: 372 AENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNF 431
           +E +IF +MG++    +NH +N  F+        + RA  ++ L+ ++N  R   + +  
Sbjct: 370 SETLIFIFMGVST-VGKNHEWNWAFVCFTLAFCLMWRALGVFVLTQVINRFRTIPLTFKD 428

Query: 432 QHMMMFSGLRGAIAFALA--IRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQI 489
           Q ++ + GLRGAI FAL   +       K++  T  ++++FFTV++ G    P++ +L +
Sbjct: 429 QFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDV 488

Query: 490 RVGVDLDENLKEDPSSQHQEANNLDKNMTKAESA------RLFR-MWYSFDHKYLKPILT 542
           +       N K+   S+       D   T  E          +R  +  FD KYL+ +L 
Sbjct: 489 K-----RSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLI 543

Query: 543 HSGPP 547
               P
Sbjct: 544 RENQP 548


>gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]
          Length = 815

 Score =  197 bits (502), Expect = 2e-50
 Identities = 125/377 (33%), Positives = 206/377 (54%), Gaps = 12/377 (3%)

Query: 132 EIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMIHA 191
           ++FF  LLPPII  AGY L  R F +NLG+IL +A +GT  +   +G +MY     ++  
Sbjct: 159 DVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAV--CLVGG 216

Query: 192 GQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLT 251
            Q+ N      D L FGS++SA DPV VLA+F E+H++  L+ L+FGES+LNDAV +VL 
Sbjct: 217 EQINN--IGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLY 274

Query: 252 YSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPML 311
           +    ++  E+    D    F S   F  +  G   +G  Y +I A  ++FT      ++
Sbjct: 275 HLFEEFANYEHVGIVDIFLGFLS---FFVVALGGVLVGVVYGVIAAFTSRFTS--HIRVI 329

Query: 312 ETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFL 371
           E    FL S+ A+LSAE   L+GI+A++  GV    Y   N+S  S    K   +  + +
Sbjct: 330 EPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSV 389

Query: 372 AENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNF 431
           +E +IF ++G++     +H +N  F++   L   +AR   +  L++ +N  R  K+    
Sbjct: 390 SETLIFIFLGVSTVAGSHH-WNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKD 448

Query: 432 QHMMMFSGLRGAIAFALA-IRNTESQPKQMMFTTTLL-LVFFTVWVFGGGTTPMLTWLQI 489
           Q ++ + GLRGAIAF+L  + + +  P   +F T ++ ++FFTV+V G    P++  L +
Sbjct: 449 QFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAV 508

Query: 490 RVGVDLDENLKEDPSSQ 506
           +   +   ++ E+  +Q
Sbjct: 509 KKKQETKRSINEEIHTQ 525


>gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]
          Length = 1177

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 71/361 (19%), Positives = 148/361 (40%), Gaps = 41/361 (11%)

Query: 131 PEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMIH 190
           P++FF +  P + F   + +      +    IL  +  G  ++ I++          + H
Sbjct: 76  PDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILV----------LWH 125

Query: 191 AGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVL 250
              +       T  L F +++ ++DP+   A   +L +   L +L+ GES++   ++++ 
Sbjct: 126 LASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLIT 185

Query: 251 TYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEF-- 308
             SI  +  +         A  + VG        SF  G    I+++ L +F     F  
Sbjct: 186 FTSIMDFDQRLQSKRNHTLA-EEIVGGICSYIIASFLFG----ILSSKLIQFWMSTVFGD 240

Query: 309 PMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFM 368
            +    L F + +  F   E  G++GI  +   G+       N+ S  + I    L EF 
Sbjct: 241 DVNHISLIFSILYLIFYICELVGMSGIFTLAIVGL-----LLNSTSFKAAIEETLLLEFW 295

Query: 369 NFL---AENVIFCYMGLALFTFQNHIF----NALFILGAFLAIFVARACNIYPLSFLLN- 420
            FL   A  ++F + GL L     +++    +  + L  +L + V R   +  +S +L+ 
Sbjct: 296 TFLSRIAFLMVFTFFGL-LIPAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPVLSR 354

Query: 421 LGRKQKIPWNFQHMMMFSGLRG--------AIAFALAIRNTESQPKQMMFTTTLLLVFFT 472
           +G   +  W +  +M+ S ++G         +A++     ++ +  Q++F   L+ +   
Sbjct: 355 VG--HEFSWRWIFIMVCSEMKGMPNINMALLLAYSDLYFGSDKEKSQILFHGVLVCLITL 412

Query: 473 V 473
           V
Sbjct: 413 V 413


>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
          Length = 1124

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 68/323 (21%), Positives = 126/323 (39%), Gaps = 45/323 (13%)

Query: 129 FDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAM 188
           F P I F V L        Y+LKK  F+Q    +L    +  + + I+IG ++  F K  
Sbjct: 96  FSPLIIFMVALDVEF----YTLKKM-FWQ----VLLTGLISFSTASIIIGYVVIKFNK-- 144

Query: 189 IHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAI 248
                     +    CL F   +   DP+  +     + +      L+ GES++  ++A 
Sbjct: 145 --------DSWDLQSCLLFSITLGIIDPLRSVNSLKTIGISKIYIDLIRGESLIICSIA- 195

Query: 249 VLTYSISIYSPKENPNAFDAAAFFQ-SVGNFLGI-FAGSFAMG--SAYAIITALLTKFTK 304
                 SI+      N    + F    VG  L     GS   G   A  I   L   F+ 
Sbjct: 196 ------SIFFGNFRGNRIHFSIFRDLHVGIELSYDILGSIIFGYWCAKIIQCILADVFSN 249

Query: 305 LCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQL 364
           +    +    L F + +  F   E  G++G +A+   G+     T+       ++   + 
Sbjct: 250 M----LTNIILCFSMVYMTFYIVEFLGMSGTLALAAVGLNLDSLTF---KPKIELVITKF 302

Query: 365 FEFMNFLAENVIFCYMGLA-----LFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLL 419
               + + E++I+ + G+      L  ++ H    +FIL  F  + + R   I  +S +L
Sbjct: 303 LRIFSSVYEHLIYAFFGIVIGCGELSHYEFHTIPFIFIL--FTTVNLVRLLTILLVSPIL 360

Query: 420 NLGRKQKIPWNFQHMMMFSGLRG 442
            +    +  W +  ++ +SG++G
Sbjct: 361 -MHSNYEYNWRWGVVITWSGIKG 382


>gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo
           sapiens]
          Length = 646

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 55/224 (24%), Positives = 88/224 (39%), Gaps = 50/224 (22%)

Query: 150 LKKRHFFQNL-GSILTYA-FLGTAISCIVIGLIMYGFVKAMIHAGQLKNGDFHFTDCLFF 207
           L KR F   L  ++LT+  F+   +  ++IGL+        +H G   +  F+ T CLFF
Sbjct: 377 LFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLY-------LHIGDDASKVFNNTGCLFF 429

Query: 208 GSL--MSATDPVTVL------AIFHELHVDP----DLYTLLFGESVLNDAVAIVLTYSIS 255
             L  M A    TVL      A+F   H++       Y L    + +   V   + Y   
Sbjct: 430 SMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSI 489

Query: 256 IY----SPKENPN-------AFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTK 304
           +Y     P E          A   A   QS+G  +G  + S  + +    +TA+      
Sbjct: 490 VYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAI------ 543

Query: 305 LCEFPMLETGLFFL--------LSWSAFLSAEAAGLTGIVAVLF 340
               P+L    FF+        L WS++LS    G  G++  ++
Sbjct: 544 ----PVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIY 583


>gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo
           sapiens]
          Length = 646

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 55/224 (24%), Positives = 88/224 (39%), Gaps = 50/224 (22%)

Query: 150 LKKRHFFQNL-GSILTYA-FLGTAISCIVIGLIMYGFVKAMIHAGQLKNGDFHFTDCLFF 207
           L KR F   L  ++LT+  F+   +  ++IGL+        +H G   +  F+ T CLFF
Sbjct: 377 LFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLY-------LHIGDDASKVFNNTGCLFF 429

Query: 208 GSL--MSATDPVTVL------AIFHELHVDP----DLYTLLFGESVLNDAVAIVLTYSIS 255
             L  M A    TVL      A+F   H++       Y L    + +   V   + Y   
Sbjct: 430 SMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSI 489

Query: 256 IY----SPKENPN-------AFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTK 304
           +Y     P E          A   A   QS+G  +G  + S  + +    +TA+      
Sbjct: 490 VYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAI------ 543

Query: 305 LCEFPMLETGLFFL--------LSWSAFLSAEAAGLTGIVAVLF 340
               P+L    FF+        L WS++LS    G  G++  ++
Sbjct: 544 ----PVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIY 583


>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 237 FGESVLNDAVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIIT 296
           +GES+L   +  + + S++I+S      +F    F    G        S  M +  A ++
Sbjct: 52  YGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGR-----RNSMLMMNLLAFVS 106

Query: 297 ALLTKFTKLCE-FPMLETGLFFL 318
           A+L  F+KL + F ML  G F +
Sbjct: 107 AVLMGFSKLGKSFEMLILGRFII 129


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
           [Homo sapiens]
          Length = 1736

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 4/70 (5%)

Query: 557 GPISRLLTSP--QAYGEQLKEDDVECIVNQDELAINYQEQAS--SPCSPPARLGLDQKAS 612
           G +  L   P  QA  E  ++ ++EC   Q E   N Q   +  SP   P+RL   Q   
Sbjct: 203 GDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQE 262

Query: 613 PQTPGKENIY 622
           PQ+   E++Y
Sbjct: 263 PQSQPTESLY 272


>gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence b [Homo sapiens]
          Length = 982

 Score = 30.0 bits (66), Expect = 6.9
 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)

Query: 521 ESARLFRMWYSFDHKYLKPILTHSGPPLTTTLP--EWCGPISRLLTSPQAYGEQLKEDDV 578
           E A++F   +    +Y  P      PP+TT LP  +  GP++  L+  +   + ++EDD 
Sbjct: 650 EGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLS--EKTRDPVEEDDD 707

Query: 579 EC-IVNQDELAINYQEQASSPCSPPAR------LGLDQKASPQTPGKENIYEGDLGLGG 630
           E  I +   +++N Q        PP R        L+    P +  K NI +  + L G
Sbjct: 708 EYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKG 766


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 30.0 bits (66), Expect = 6.9
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 9/88 (10%)

Query: 539 PILTHSGPPLTTT-----LPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAIN--- 590
           P    +GP   TT     +P+    +S +L   Q + E  K D    + N  + A+    
Sbjct: 451 PAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSK-DKKPALGNHHDPAVPRAP 509

Query: 591 YQEQASSPCSPPARLGLDQKASPQTPGK 618
           +  ++S P  PP R   D   SP TP K
Sbjct: 510 HAPKSSLPPPPPVRRSSDTSGSPATPLK 537


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,110,346
Number of Sequences: 37866
Number of extensions: 987530
Number of successful extensions: 2965
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2906
Number of HSP's gapped (non-prelim): 24
length of query: 645
length of database: 18,247,518
effective HSP length: 109
effective length of query: 536
effective length of database: 14,120,124
effective search space: 7568386464
effective search space used: 7568386464
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.