Search of human proteins with 27734719

Search of human proteins with 27734719

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27734719 solute carrier family 19, member 2 [Homo sapiens]
         (497 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27734719 solute carrier family 19, member 2 [Homo sapiens]         994   0.0  
gi|13376856 solute carrier family 19, member 3 [Homo sapiens]         484   e-137
gi|34808710 solute carrier family 19 member 1 [Homo sapiens]          341   8e-94
gi|241982806 hypothetical protein LOC56918 isoform 2 [Homo sapiens]    48   2e-05
gi|241982804 hypothetical protein LOC56918 isoform 1 [Homo sapiens]    48   2e-05
gi|20127561 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1...    32   1.3  
gi|209862760 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, ...    32   1.3  
gi|157671931 solute carrier family 5 (sodium/glucose cotransport...    32   1.7  
gi|8922116 hypothetical protein LOC11094 isoform a [Homo sapiens]      31   2.3  
gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform...    30   3.9  
gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform...    30   3.9  
gi|31563526 solute carrier family 24 (sodium/potassium/calcium e...    30   3.9  
gi|31542327 solute carrier family 22, member 16 [Homo sapiens]         30   3.9  
gi|17318565 cyclin E2 [Homo sapiens]                                   30   6.6  
gi|134152683 transmembrane protein 214 isoform 2 [Homo sapiens]        30   6.6  
gi|134152721 transmembrane protein 214 isoform 1 [Homo sapiens]        30   6.6  

>gi|27734719 solute carrier family 19, member 2 [Homo sapiens]
          Length = 497

 Score =  994 bits (2571), Expect = 0.0
 Identities = 497/497 (100%), Positives = 497/497 (100%)

Query: 1   MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGP 60
           MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGP
Sbjct: 1   MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGP 60

Query: 61  DKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQG 120
           DKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQG
Sbjct: 61  DKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQG 120

Query: 121 LLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILV 180
           LLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILV
Sbjct: 121 LLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILV 180

Query: 181 SVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTD 240
           SVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTD
Sbjct: 181 SVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTD 240

Query: 241 TPASNHLPGWEDIESKIPLNMEEPPVEEPEPKPDRLLVLKVLWNDFLMCYSSRPLLCWSV 300
           TPASNHLPGWEDIESKIPLNMEEPPVEEPEPKPDRLLVLKVLWNDFLMCYSSRPLLCWSV
Sbjct: 241 TPASNHLPGWEDIESKIPLNMEEPPVEEPEPKPDRLLVLKVLWNDFLMCYSSRPLLCWSV 300

Query: 301 WWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWST 360
           WWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWST
Sbjct: 301 WWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWST 360

Query: 361 WGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERY 420
           WGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERY
Sbjct: 361 WGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERY 420

Query: 421 ALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAVSVMK 480
           ALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAVSVMK
Sbjct: 421 ALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAVSVMK 480

Query: 481 KCRKLEDPQSSSQVTTS 497
           KCRKLEDPQSSSQVTTS
Sbjct: 481 KCRKLEDPQSSSQVTTS 497


>gi|13376856 solute carrier family 19, member 3 [Homo sapiens]
          Length = 496

 Score =  484 bits (1246), Expect = e-137
 Identities = 237/447 (53%), Positives = 314/447 (70%), Gaps = 9/447 (2%)

Query: 30  WFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVF 89
           W  PT +LC +GFF+ +RPSEPFL PYL GPDKNLT  E+ NEI+PVWTYSYLVLL PVF
Sbjct: 12  WIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAEITNEIFPVWTYSYLVLLLPVF 71

Query: 90  LATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVV 149
           + TDY+RYKPV++LQG+S I+TW +LL+ QG+  +Q +EFFYG+ TA E+AYY+YIYSVV
Sbjct: 72  VLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTAAEVAYYAYIYSVV 131

Query: 150 DLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLP 209
               YQ+V+ YCRS TL  +T GSVL Q+LVS+A  S F LNVISL  VSVAF  + FLP
Sbjct: 132 SPEHYQRVSGYCRSVTLAAYTAGSVLAQLLVSLANMSYFYLNVISLASVSVAFLFSLFLP 191

Query: 210 MPQKSLFFHHIPSTCQRVNGIKVQNGGIVTDTPASNHLPGWEDIESKIPL-----NMEEP 264
           MP+KS+FFH  PS   +    K  +   V +       PG E+ +    +      + + 
Sbjct: 192 MPKKSMFFHAKPSREIK----KSSSVNPVLEETHEGEAPGCEEQKPTSEILSTSGKLNKG 247

Query: 265 PVEEPEPKPDRLLVLKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVM 324
            +   +P    + V    + D   CYSS+ L  WS+WWA +T G+ QV+NY Q LW+   
Sbjct: 248 QLNSLKPSNVTVDVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQVLNYVQILWDYKA 307

Query: 325 PSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTVG 384
           PS+ ++IYNG VEA++T  GAVA FAVGY+K++W   GE+ L +FS++ A ++++M    
Sbjct: 308 PSQDSSIYNGAVEAIATFGGAVAAFAVGYVKVNWDLLGELALVVFSVVNAGSLFLMHYTA 367

Query: 385 NIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVD 444
           NIW CYA Y++F+  YMLLITIA FQIA NL++ERYALVFG+NTFIAL +QT++T+IVVD
Sbjct: 368 NIWACYAGYLIFKSSYMLLITIAVFQIAVNLNVERYALVFGINTFIALVIQTIMTVIVVD 427

Query: 445 ASGLGLEITTQFLIYASYFALIAVVFL 471
             GL L ++ QFL+Y SYFA+IA +FL
Sbjct: 428 QRGLNLPVSIQFLVYGSYFAVIAGIFL 454


>gi|34808710 solute carrier family 19 member 1 [Homo sapiens]
          Length = 591

 Score =  341 bits (875), Expect = 8e-94
 Identities = 185/473 (39%), Positives = 265/473 (56%), Gaps = 45/473 (9%)

Query: 30  WFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVF 89
           W      LC YGF A +RP E F+TPYLLGPDKN T  +V NEI PV +YSYL +L PVF
Sbjct: 25  WRHLVCYLCFYGFMAQIRPGESFITPYLLGPDKNFTREQVTNEITPVLSYSYLAVLVPVF 84

Query: 90  LATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVV 149
           L TDYLRY PV+LLQGLS +  W +LL    +  +Q +E FY +  A  IAY SYI+S+V
Sbjct: 85  LLTDYLRYTPVLLLQGLSFVSVWLLLLLGHSVAHMQLMELFYSVTMAARIAYSSYIFSLV 144

Query: 150 DLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLP 209
               YQ+V  Y R+A L+G    SVLGQ+LV+V   S  +LN ISL  ++ +  +A FL 
Sbjct: 145 RPARYQRVAGYSRAAVLLGVFTSSVLGQLLVTVGRVSFSTLNYISLAFLTFSVVLALFLK 204

Query: 210 MPQKSLFFHHIPSTCQRVNGIKVQNGGIVTDTPASNHLPGWEDIESKIPLNMEEPPVEEP 269
            P++SLFF+                                 D   +   +  E     P
Sbjct: 205 RPKRSLFFN--------------------------------RDDRGRCETSASELERMNP 232

Query: 270 EPKPDRLLVLKVLWNDFLMCYSSR---------PLLCWSVWWALSTCGYFQVVNYTQGLW 320
            P       L+V   D ++    R          L  WS+WW  ++ GY+ VV Y   LW
Sbjct: 233 GPGGKLGHALRVACGDSVLARMLRELGDSLRRPQLRLWSLWWVFNSAGYYLVVYYVHILW 292

Query: 321 EKVMPSRYAA-IYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYI 379
            +V P+  +A +YNG  +A STLLGA+  FA G++KI W+ W ++ ++  +   A  V++
Sbjct: 293 NEVDPTTNSARVYNGAADAASTLLGAITSFAAGFVKIRWARWSKLLIAGVTATQAGLVFL 352

Query: 380 MDTV---GNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQT 436
           +       +IW+CYA++V+FR  Y  L+ IATFQIA++LS E  ALVFGVNTF A  ++T
Sbjct: 353 LAHTRHPSSIWLCYAAFVLFRGSYQFLVPIATFQIASSLSKELCALVFGVNTFFATIVKT 412

Query: 437 LLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAVSVMKKCRKLEDPQ 489
           ++T IV D  GLGL +  QF +Y+ YF ++++++     +  ++ C++   P+
Sbjct: 413 IITFIVSDVRGLGLPVRKQFQLYSVYFLILSIIYFLGAMLDGLRHCQRGHHPR 465


>gi|241982806 hypothetical protein LOC56918 isoform 2 [Homo sapiens]
          Length = 96

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 22/39 (56%), Positives = 28/39 (71%)

Query: 417 MERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQ 455
           ME YAL FG+N FIAL +Q ++T+ VVD  GLGL +  Q
Sbjct: 1   MEDYALTFGINPFIALMIQPIVTMTVVDNQGLGLPVDIQ 39


>gi|241982804 hypothetical protein LOC56918 isoform 1 [Homo sapiens]
          Length = 150

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 22/39 (56%), Positives = 28/39 (71%)

Query: 417 MERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQ 455
           ME YAL FG+N FIAL +Q ++T+ VVD  GLGL +  Q
Sbjct: 1   MEDYALTFGINPFIALMIQPIVTMTVVDNQGLGLPVDIQ 39


>gi|20127561 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11,
           17.3kDa isoform 1 [Homo sapiens]
          Length = 163

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 39/108 (36%), Positives = 48/108 (44%), Gaps = 17/108 (15%)

Query: 5   GPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGP---D 61
           G  +RR  AAAAT  L  ARVR E  F  T +  A    A  RP EP  TP+   P   D
Sbjct: 7   GLSARRLLAAAATRGLPAARVRWESSFSRTVV--APSAVAGKRPPEP-TTPWQEDPEPED 63

Query: 62  KNLTEREVFNEIY------PVWTYSYLVLLFPV----FLATDYLRYKP 99
           +NL E+   +  Y       VW    LV  F V     L + ++ Y P
Sbjct: 64  ENLYEKNPDSHGYDKDPVLDVWNMR-LVFFFGVSIILVLGSTFVAYLP 110


>gi|209862760 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11,
           17.3kDa isoform 2 [Homo sapiens]
          Length = 153

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 39/108 (36%), Positives = 48/108 (44%), Gaps = 17/108 (15%)

Query: 5   GPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGP---D 61
           G  +RR  AAAAT  L  ARVR E  F  T +  A    A  RP EP  TP+   P   D
Sbjct: 7   GLSARRLLAAAATRGLPAARVRWESSFSRTVV--APSAVAGKRPPEP-TTPWQEDPEPED 63

Query: 62  KNLTEREVFNEIY------PVWTYSYLVLLFPV----FLATDYLRYKP 99
           +NL E+   +  Y       VW    LV  F V     L + ++ Y P
Sbjct: 64  ENLYEKNPDSHGYDKDPVLDVWNMR-LVFFFGVSIILVLGSTFVAYLP 110


>gi|157671931 solute carrier family 5 (sodium/glucose
           cotransporter), member 12 [Homo sapiens]
          Length = 618

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 13/117 (11%)

Query: 360 TWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIAT-------FQIA 412
           ++G + LSL +  ++A V ++ T   ++   AS++VF I Y+ +I + +       ++  
Sbjct: 49  SFGPVGLSLTASFMSA-VTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSG 107

Query: 413 ANLSMERYALVFG-----VNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFA 464
              + E   L F        T I +    L T +VV A  L L   T F ++ S FA
Sbjct: 108 ITSTYEYLQLRFNKPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFA 164


>gi|8922116 hypothetical protein LOC11094 isoform a [Homo sapiens]
          Length = 172

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 31/138 (22%), Positives = 57/138 (41%), Gaps = 23/138 (16%)

Query: 77  WTYSYLVLLFPVFLAT--------DYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLE 128
           W Y +L  L  V  A         + +   P+ +  G+ +I+  F+LL  +     QF+E
Sbjct: 25  WWYRWLCRLSGVLGAVSCAISGLFNCITIHPLNIAAGVWMIMNAFILLLCEAPFCCQFIE 84

Query: 129 FFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSAT---LVGFTVGSVLGQILVSVAGW 185
           F   +A             V  L  +QK   YC  A    ++  T+ ++LG  +    G 
Sbjct: 85  FANTVAE-----------KVDRLRSWQKAVFYCGMAVVPIVISLTLTTLLGNAIAFATG- 132

Query: 186 SLFSLNVISLTCVSVAFA 203
            L+ L+ +     ++++A
Sbjct: 133 VLYGLSALGKKGDAISYA 150


>gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform a
           [Homo sapiens]
          Length = 2436

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 42/189 (22%), Positives = 78/189 (41%), Gaps = 19/189 (10%)

Query: 284 NDFLMCYSSRPLLCWSVWWALSTCGYFQ-VVNYTQGLWEKVMPSRYAAIYNGGVEAVSTL 342
           +DFL        LC  + W  S     Q +V   +   ++VM +            ++  
Sbjct: 698 DDFLFVIEHMMPLCMVISWVYSVAMTIQHIVAEKEHRLKEVMKTM----------GLNNA 747

Query: 343 LGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYML 402
           +  VA F  G++++S S       +L ++L    V +   V  IW+  A Y V  I++  
Sbjct: 748 VHWVAWFITGFVQLSISV-----TALTAILKYGQVLMHSHVVIIWLFLAVYAVATIMFCF 802

Query: 403 LITI--ATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVV-DASGLGLEITTQFLIY 459
           L+++  +  ++A+      Y L +    ++A+  +     I   +     L  TT F + 
Sbjct: 803 LVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAHDKITAFEKCIASLMSTTAFGLG 862

Query: 460 ASYFALIAV 468
           + YFAL  V
Sbjct: 863 SKYFALYEV 871


>gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform b
           [Homo sapiens]
          Length = 2466

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 42/189 (22%), Positives = 78/189 (41%), Gaps = 19/189 (10%)

Query: 284 NDFLMCYSSRPLLCWSVWWALSTCGYFQ-VVNYTQGLWEKVMPSRYAAIYNGGVEAVSTL 342
           +DFL        LC  + W  S     Q +V   +   ++VM +            ++  
Sbjct: 728 DDFLFVIEHMMPLCMVISWVYSVAMTIQHIVAEKEHRLKEVMKTM----------GLNNA 777

Query: 343 LGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYML 402
           +  VA F  G++++S S       +L ++L    V +   V  IW+  A Y V  I++  
Sbjct: 778 VHWVAWFITGFVQLSISV-----TALTAILKYGQVLMHSHVVIIWLFLAVYAVATIMFCF 832

Query: 403 LITI--ATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVV-DASGLGLEITTQFLIY 459
           L+++  +  ++A+      Y L +    ++A+  +     I   +     L  TT F + 
Sbjct: 833 LVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAHDKITAFEKCIASLMSTTAFGLG 892

Query: 460 ASYFALIAV 468
           + YFAL  V
Sbjct: 893 SKYFALYEV 901


>gi|31563526 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 3 [Homo sapiens]
          Length = 644

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 47/184 (25%), Positives = 76/184 (41%), Gaps = 31/184 (16%)

Query: 298 WSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTL-LGAVAVFAVGYIKI 356
           W+  W LS   YF V N  +  WEK     +A+         STL + A +   V  + I
Sbjct: 450 WAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFAS---------STLWIAAFSYMMVWMVTI 500

Query: 357 SWSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLS 416
              T G   + +    +AA   + D       C AS +V R        +    ++ ++ 
Sbjct: 501 IGYTLGIPDVIMGITFLAAGTSVPD-------CMASLIVAR------QGMGDMAVSNSIG 547

Query: 417 MERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAV 476
              + ++ G+   +  ALQTL     VD  G  + + ++ LIY S   L+A VF+    V
Sbjct: 548 SNVFDILIGLG--LPWALQTL----AVD-YGSYIRLNSRGLIY-SVGLLLASVFVTVFGV 599

Query: 477 SVMK 480
            + K
Sbjct: 600 HLNK 603


>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
          Length = 577

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 65/302 (21%), Positives = 114/302 (37%), Gaps = 60/302 (19%)

Query: 129 FFYGIATATEIAYYSYIYSVVDLGMYQK---VTSYCRSATLVGF---TVGSV-------L 175
           F +GIA A  + YY+++ +   L M      V  +      +G    T  SV       +
Sbjct: 193 FLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAV 252

Query: 176 GQILVSVAGWSL--FSLNVISLTCVSVAFAV-AWFLPMPQKSLFFHHIPSTCQRVNGIKV 232
           G +LV++ G+ +  + L  + L+ V+V F +  W LP     L         Q+      
Sbjct: 253 GTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQK------ 306

Query: 233 QNGGIVTDTPASNHLPGWEDIESKIPLNMEEPPVEEP-EPKPDRLLVLKVLWNDFLMCYS 291
                + D  A  +      +   + L+++ P    P E +   L  L   W+      +
Sbjct: 307 -----IVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWS-----IT 356

Query: 292 SRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVST-LLGAVAVFA 350
            R L  W +W+  S   Y   +N               ++  GG E ++  LLG V + A
Sbjct: 357 KRTLTVWLIWFTGSLGFYSFSLN---------------SVNLGGNEYLNLFLLGVVEIPA 401

Query: 351 VGYIKISWSTWGEMTLSLFSLLIAAAV-----------YIMDTVGNIWVCYASYVVFRII 399
             ++ I+    G  T+  +SL  +A             YI+  V  +   +A    F +I
Sbjct: 402 YTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLI 461

Query: 400 YM 401
           Y+
Sbjct: 462 YL 463


>gi|17318565 cyclin E2 [Homo sapiens]
          Length = 404

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 28/76 (36%), Positives = 37/76 (48%), Gaps = 7/76 (9%)

Query: 72  EIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGL--LAIQFLEF 129
           E+ PV   S+L L    FL  D L+  P VLL   S   T+  +     L  LAI  LEF
Sbjct: 237 ELCPVTIISWLNL----FLQVDALKDAPKVLLPQYSQ-ETFIQIAQLLDLCILAIDSLEF 291

Query: 130 FYGIATATEIAYYSYI 145
            Y I TA  + +++ I
Sbjct: 292 QYRILTAAALCHFTSI 307


>gi|134152683 transmembrane protein 214 isoform 2 [Homo sapiens]
          Length = 644

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 285 DFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGL--WEKVM 324
           + L  + SRP  C ++ WAL   G+    N T+GL  W  +M
Sbjct: 198 ELLRSHQSRPAKCLTIMWALGQAGF---ANLTEGLKVWLGIM 236


>gi|134152721 transmembrane protein 214 isoform 1 [Homo sapiens]
          Length = 689

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 5/42 (11%)

Query: 285 DFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGL--WEKVM 324
           + L  + SRP  C ++ WAL   G+    N T+GL  W  +M
Sbjct: 243 ELLRSHQSRPAKCLTIMWALGQAGF---ANLTEGLKVWLGIM 281


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.138    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,471,339
Number of Sequences: 37866
Number of extensions: 775994
Number of successful extensions: 2536
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2523
Number of HSP's gapped (non-prelim): 19
length of query: 497
length of database: 18,247,518
effective HSP length: 106
effective length of query: 391
effective length of database: 14,233,722
effective search space: 5565385302
effective search space used: 5565385302
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.