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Search of human proteins with 25092733
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]
(497 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens] 1043 0.0
gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens] 967 0.0
gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens] 905 0.0
gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens] 775 0.0
gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens] 711 0.0
gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens] 660 0.0
gi|28416927 purinergic receptor P2X4 [Homo sapiens] 330 1e-90
gi|28416925 purinergic receptor P2X3 [Homo sapiens] 322 6e-88
gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens] 295 6e-80
gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens] 285 7e-77
gi|4505545 purinergic receptor P2X1 [Homo sapiens] 285 9e-77
gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens] 259 5e-69
gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens] 257 1e-68
gi|29294631 purinergic receptor P2X7 [Homo sapiens] 235 8e-62
gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens] 148 1e-35
gi|150170670 piccolo isoform 2 [Homo sapiens] 38 0.019
gi|150378539 piccolo isoform 1 [Homo sapiens] 38 0.019
gi|54860079 nadrin isoform 1 [Homo sapiens] 37 0.041
gi|54860105 nadrin isoform 2 [Homo sapiens] 37 0.041
gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens] 37 0.054
gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens] 37 0.054
gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens] 37 0.054
gi|215820652 StAR-related lipid transfer (START) domain containi... 37 0.054
gi|215820650 StAR-related lipid transfer (START) domain containi... 37 0.054
gi|31543659 StAR-related lipid transfer (START) domain containin... 37 0.054
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 36 0.071
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 36 0.092
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 36 0.092
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 36 0.092
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 35 0.12
>gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]
Length = 497
Score = 1043 bits (2698), Expect = 0.0
Identities = 497/497 (100%), Positives = 497/497 (100%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
Query: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
Query: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
Query: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
Query: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLW 360
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLW
Sbjct: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLW 360
Query: 361 GPSGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 420
GPSGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT
Sbjct: 361 GPSGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 420
Query: 421 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 480
LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS
Sbjct: 421 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 480
Query: 481 EPAQASTPTDPKGLAQL 497
EPAQASTPTDPKGLAQL
Sbjct: 481 EPAQASTPTDPKGLAQL 497
>gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]
Length = 471
Score = 967 bits (2500), Expect = 0.0
Identities = 471/497 (94%), Positives = 471/497 (94%), Gaps = 26/497 (5%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
Query: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
Query: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
Query: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
Query: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLW 360
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV
Sbjct: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV------ 354
Query: 361 GPSGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 420
GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT
Sbjct: 355 --------------------GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 394
Query: 421 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 480
LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS
Sbjct: 395 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 454
Query: 481 EPAQASTPTDPKGLAQL 497
EPAQASTPTDPKGLAQL
Sbjct: 455 EPAQASTPTDPKGLAQL 471
>gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]
Length = 447
Score = 905 bits (2340), Expect = 0.0
Identities = 447/497 (89%), Positives = 447/497 (89%), Gaps = 50/497 (10%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE----------------- 103
Query: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 104 -------SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 156
Query: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 157 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 216
Query: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 217 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 276
Query: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLW 360
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV
Sbjct: 277 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV------ 330
Query: 361 GPSGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 420
GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT
Sbjct: 331 --------------------GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 370
Query: 421 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 480
LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS
Sbjct: 371 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 430
Query: 481 EPAQASTPTDPKGLAQL 497
EPAQASTPTDPKGLAQL
Sbjct: 431 EPAQASTPTDPKGLAQL 447
>gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]
Length = 404
Score = 775 bits (2000), Expect = 0.0
Identities = 384/426 (90%), Positives = 386/426 (90%), Gaps = 37/426 (8%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
Query: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
Query: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
Query: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
Query: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLW 360
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV
Sbjct: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV------ 354
Query: 361 GPSGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKV-----------CT 409
GSFLCDWILLTFMNKNKVYSHKKFDK+ T
Sbjct: 355 --------------------GSFLCDWILLTFMNKNKVYSHKKFDKMVDTPASEPAQAST 394
Query: 410 PSHPSG 415
P+ P G
Sbjct: 395 PTDPKG 400
Score = 52.8 bits (125), Expect = 7e-07
Identities = 24/26 (92%), Positives = 26/26 (100%)
Query: 472 EQMVDTPASEPAQASTPTDPKGLAQL 497
++MVDTPASEPAQASTPTDPKGLAQL
Sbjct: 379 DKMVDTPASEPAQASTPTDPKGLAQL 404
>gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]
Length = 379
Score = 711 bits (1834), Expect = 0.0
Identities = 344/370 (92%), Positives = 344/370 (92%), Gaps = 26/370 (7%)
Query: 128 SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQF 187
SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQF
Sbjct: 36 SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQF 95
Query: 188 LGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEK 247
LGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEK
Sbjct: 96 LGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEK 155
Query: 248 AGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYY 307
AGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYY
Sbjct: 156 AGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYY 215
Query: 308 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLWGPSGCGG 367
KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV
Sbjct: 216 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV------------- 262
Query: 368 STRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQ 427
GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQ
Sbjct: 263 -------------GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQ 309
Query: 428 APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQAST 487
APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQAST
Sbjct: 310 APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQAST 369
Query: 488 PTDPKGLAQL 497
PTDPKGLAQL
Sbjct: 370 PTDPKGLAQL 379
Score = 77.8 bits (190), Expect = 2e-14
Identities = 35/35 (100%), Positives = 35/35 (100%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV 35
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV 35
>gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]
Length = 399
Score = 660 bits (1702), Expect = 0.0
Identities = 319/345 (92%), Positives = 319/345 (92%), Gaps = 26/345 (7%)
Query: 153 GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 212
GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK
Sbjct: 81 GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 140
Query: 213 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 272
GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL
Sbjct: 141 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 200
Query: 273 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 332
DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ
Sbjct: 201 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 260
Query: 333 AGKFSLIPTIINLATALTSVGVVRNPLWGPSGCGGSTRPLHTGLCWPQGSFLCDWILLTF 392
AGKFSLIPTIINLATALTSVGV GSFLCDWILLTF
Sbjct: 261 AGKFSLIPTIINLATALTSVGV--------------------------GSFLCDWILLTF 294
Query: 393 MNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQG 452
MNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQG
Sbjct: 295 MNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQG 354
Query: 453 AECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 497
AECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 355 AECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 399
Score = 82.0 bits (201), Expect = 1e-15
Identities = 38/40 (95%), Positives = 38/40 (95%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRR 40
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVR R
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRIHR 40
>gi|28416927 purinergic receptor P2X4 [Homo sapiens]
Length = 388
Score = 330 bits (847), Expect = 1e-90
Identities = 185/403 (45%), Positives = 250/403 (62%), Gaps = 45/403 (11%)
Query: 20 GCWSAL----WDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPE 75
GC +AL ++Y+TP+++++R+R++G++ RAVQLLIL Y + +VF+ +K YQE+++
Sbjct: 3 GCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDS-VV 61
Query: 76 SSIITKVKGITTSE-----HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIR 130
SS+ TKVKG+ + ++WDV +YV P + + ++T V T +QTQG CPE I
Sbjct: 62 SSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPE-IP 120
Query: 131 VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ--FL 188
C SDA C AG NG+ TGRCV + G KTCEV WCPVED V Q FL
Sbjct: 121 DATTVCKSDASCTAGSAGTHSNGVSTGRCVAF-NGSVKTCEVAAWCPVEDDTHVPQPAFL 179
Query: 189 GTMAPNFTILIKNSIHYPKFHFSKGNIADR-TDGYLKRCTFHEASDLYCPIFKLGFIVEK 247
A NFT+L+KN+I YPKF+FSK NI T YLK C + +D +CPIF+LG IVE
Sbjct: 180 KA-AENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVEN 238
Query: 248 AGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVP--ASSGYNFRFAK 305
AG SF ++A +GG++G+ +NWDC+LD AS C P+YSFRRLD + V S GYNFRFAK
Sbjct: 239 AGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAK 298
Query: 306 YYK-INGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLWGPSG 364
YY+ + G RTLIKAYGIR D+IV G+AGKF +IPT+IN+ + L +G+
Sbjct: 299 YYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGM---------- 348
Query: 365 CGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKV 407
+ LCD I+L M K Y KK+ V
Sbjct: 349 ----------------ATVLCDIIVLYCMKKRLYYREKKYKYV 375
>gi|28416925 purinergic receptor P2X3 [Homo sapiens]
Length = 397
Score = 322 bits (824), Expect = 6e-88
Identities = 181/391 (46%), Positives = 241/391 (61%), Gaps = 36/391 (9%)
Query: 21 CWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIIT 80
C S + YET K +VV++ +G++ R VQLLI+ YFV +VF+ +K+YQ +T ESS++T
Sbjct: 3 CISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVT 62
Query: 81 KVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHNATCLSDA 140
KVKG ++V DV +YV PP+G SVF IIT++ T +Q QG CPES + C+SD+
Sbjct: 63 KVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYR--CVSDS 120
Query: 141 DCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIK 200
C G + G G+ TGRCV Y +TCE+ GWCP E +V + A NFTI IK
Sbjct: 121 QC--GPERLPGGGILTGRCV-NYSSVLRTCEIQGWCPTEVD-TVETPIMMEAENFTIFIK 176
Query: 201 NSIHYPKFHFSKGN-IADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKG 259
NSI +P F+F KGN + + T +K C FH D +CPI ++G +V+ AG+ F +LA G
Sbjct: 177 NSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTG 236
Query: 260 GVIGVIINWDCDLDLPASECNPKYSFRRLD--PKHVPASSGYNFRFAKYYKI-NGTTTRT 316
GV+G+ I W CDLD +C PKYSF RLD + S GYNFRFAKYYK+ NG+ RT
Sbjct: 237 GVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRT 296
Query: 317 LIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLWGPSGCGGSTRPLHTGL 376
L+KA+GIR DV+V+G AGKF++IPTII+ A TSVGV
Sbjct: 297 LLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGV---------------------- 334
Query: 377 CWPQGSFLCDWILLTFMNKNKVYSHKKFDKV 407
G+ LCD ILL F+ Y KKF++V
Sbjct: 335 ----GTVLCDIILLNFLKGADQYKAKKFEEV 361
>gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]
Length = 422
Score = 295 bits (755), Expect = 6e-80
Identities = 169/463 (36%), Positives = 249/463 (53%), Gaps = 67/463 (14%)
Query: 19 RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78
+G +L+DY+T K ++ +N+++G+LYR +Q IL Y V +VF+++K YQ+ +T +S++
Sbjct: 7 KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
Query: 79 ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133
ITKVKG+ TS+ ++WDV +YV P +G +VF ++T + T +Q Q C E+ + +
Sbjct: 67 ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
Query: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193
C D+DC AGE GNG++TGRC+ TCE+F WCP+E + + A
Sbjct: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 186
Query: 194 NFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAGESF 252
+FTI IKN I +PKF+FSK N+ D D +LK C F + YCPIF+LG ++ AG F
Sbjct: 187 DFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDF 245
Query: 253 TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-IN 310
++A +GGVIG+ I W+CDLD ASEC+P YSF RLD K SSGYNFRFA+YY+
Sbjct: 246 QDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAA 305
Query: 311 GTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLWGPSGCGGSTR 370
G RTL+KAYGIR DV+V+G
Sbjct: 306 GVEFRTLMKAYGIRFDVMVNG--------------------------------------- 326
Query: 371 PLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKV-----CTPSHPSGSWPVTLARVL 425
+G+F CD +L+ + K + Y KK+++V + + + L+ L
Sbjct: 327 ---------KGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQL 377
Query: 426 GQAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPLR 463
P G + + PP + G G+ C P R
Sbjct: 378 TSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 420
>gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]
Length = 441
Score = 285 bits (729), Expect = 7e-77
Identities = 172/466 (36%), Positives = 245/466 (52%), Gaps = 50/466 (10%)
Query: 10 AGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQE 69
AG+ A W L DY+T K ++ RN R+G L R +Q I++Y V + + +K YQE
Sbjct: 8 AGSMGSPGATTGWGLL-DYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQE 66
Query: 70 SETGPESSIITKVKGITTSE-----HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGT 124
+ P+ SIITK+KG++ ++ +++WDV ++VKPP+G +VF ++T T +Q QG
Sbjct: 67 RDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGR 126
Query: 125 CPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASV 184
CPE V A C D DC GE +G++TG+CV + G +TCE++ WCPVE G
Sbjct: 127 CPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCV-VFNGTHRTCEIWSWCPVESGVVP 185
Query: 185 SQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDG-YLKRCTFHEASDLYCPIFKLGF 243
S+ L A NFT+ IKN++ + KF+FSK N + D Y K C + YCP+F++G
Sbjct: 186 SRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGD 245
Query: 244 IVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRF 303
+V KAG +F +LA GG +G+ ++WDCDLD S C P YSF+ + YNFR
Sbjct: 246 LVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQE-------KSYNFRT 298
Query: 304 A-KYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLWGP 362
A +++ G RTL+K YGIR D++V GQAGKF LIPT + L T +GVV
Sbjct: 299 ATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVV------- 351
Query: 363 SGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLA 422
+F CD +LL + Y K+++ P + S LA
Sbjct: 352 -------------------TFFCDLLLLYVDREAHFYWRTKYEEAKAPKATANSVWRELA 392
Query: 423 RVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPIS 468
E RS P+P + G Q P PCP S
Sbjct: 393 LASQARLAECLRRS--SAPAPTATAAGSQ------TQTPGWPCPSS 430
>gi|4505545 purinergic receptor P2X1 [Homo sapiens]
Length = 399
Score = 285 bits (728), Expect = 9e-77
Identities = 149/399 (37%), Positives = 233/399 (58%), Gaps = 40/399 (10%)
Query: 14 ARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETG 73
ARR + L++Y+TP++++VRN+++GV++R +QL++L+Y + +VF+ +K YQ S +G
Sbjct: 2 ARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTS-SG 60
Query: 74 PESSIITKVKGITTSE-----HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPES 128
SS+ K+KG+ ++ +VWDV +YV P +G + F ++T T QTQG C E
Sbjct: 61 LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAE- 119
Query: 129 IRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-F 187
C D+ C G+ G+RTG+CV + KTCE+FGWCPVE + +
Sbjct: 120 -HPEGGICKEDSGCTPGKAKRKAQGIRTGKCVAF-NDTVKTCEIFGWCPVEVDDDIPRPA 177
Query: 188 LGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDG-YLKRCTFHEASDLYCPIFKLGFIVE 246
L A NFT+ IKNSI +P+F ++ N+ + + ++K C FH+ CP+F+LG++V+
Sbjct: 178 LLREAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQ 237
Query: 247 KAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRL-DPKHVPASSGYNFRFAK 305
++G++F+ LA KGGV+G+ I+W CDLD C P Y F L + K++ S G+NFRFA+
Sbjct: 238 ESGQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNL--SPGFNFRFAR 295
Query: 306 YYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLWGPSGC 365
++ NGT R L K +GIR D++V G+AGKF +IPT+ + + + GV
Sbjct: 296 HFVENGTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGV----------- 344
Query: 366 GGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKF 404
+ LCD +LL + K Y KKF
Sbjct: 345 ---------------ATVLCDLLLLHILPKRHYYKQKKF 368
>gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]
Length = 397
Score = 259 bits (661), Expect = 5e-69
Identities = 158/462 (34%), Positives = 234/462 (50%), Gaps = 90/462 (19%)
Query: 19 RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78
+G +L+DY+T K ++ +N+++G+LYR +Q IL Y V +VF+++K YQ+ +T +S++
Sbjct: 7 KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
Query: 79 ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133
ITKVKG+ TS+ ++WDV +YV P +Q +G + +
Sbjct: 67 ITKVKGVAFTNTSDLGQRIWDVADYVIP-----------------AQNEG-------IPD 102
Query: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193
C D+DC AGE GNG++TGRC+ TCE+F WCP+E + + A
Sbjct: 103 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 162
Query: 194 NFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFT 253
+FTI IKN I +PKF+FS + + +LK C F + YCPIF+LG ++ AG F
Sbjct: 163 DFTIFIKNHIRFPKFNFSNNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQ 221
Query: 254 ELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-ING 311
++A +GGVIG+ I W+CDLD ASEC+P YSF RLD K SSGYNFRFA+YY+ G
Sbjct: 222 DIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAG 281
Query: 312 TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLWGPSGCGGSTRP 371
RTL+KAYGIR DV+V+G
Sbjct: 282 VEFRTLMKAYGIRFDVMVNG---------------------------------------- 301
Query: 372 LHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKV-----CTPSHPSGSWPVTLARVLG 426
+G+F CD +L+ + K + Y KK+++V + + + L+ L
Sbjct: 302 --------KGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLT 353
Query: 427 QAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPLR 463
P G + + PP + G G+ C P R
Sbjct: 354 SGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 395
>gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]
Length = 415
Score = 257 bits (657), Expect = 1e-68
Identities = 153/417 (36%), Positives = 218/417 (52%), Gaps = 49/417 (11%)
Query: 59 YVFIVQKSYQESETGPESSIITKVKGITTSE-----HKVWDVEEYVKPPEGGSVFSIITR 113
+ + +K YQE + P+ SIITK+KG++ ++ +++WDV ++VKPP+G +VF ++T
Sbjct: 30 WALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTN 89
Query: 114 VEATHSQTQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVF 173
T +Q QG CPE V A C D DC GE +G++TG+CV + G +TCE++
Sbjct: 90 FLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCV-VFNGTHRTCEIW 148
Query: 174 GWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDG-YLKRCTFHEAS 232
WCPVE G S+ L A NFT+ IKN++ + KF+FSK N + D Y K C +
Sbjct: 149 SWCPVESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQF 208
Query: 233 DLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKH 292
YCP+F++G +V KAG +F +LA GG +G+ ++WDCDLD S C P YSF+ +
Sbjct: 209 SPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQE--- 265
Query: 293 VPASSGYNFRFA-KYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTS 351
YNFR A +++ G RTL+K YGIR D++V GQAGKF LIPT + L T
Sbjct: 266 ----KSYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAW 321
Query: 352 VGVVRNPLWGPSGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPS 411
+GVV +F CD +LL + Y K+++ P
Sbjct: 322 LGVV--------------------------TFFCDLLLLYVDREAHFYWRTKYEEAKAPK 355
Query: 412 HPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPIS 468
+ S LA E RS P+P + G Q P PCP S
Sbjct: 356 ATANSVWRELALASQARLAECLRRS--SAPAPTATAAGSQ------TQTPGWPCPSS 404
>gi|29294631 purinergic receptor P2X7 [Homo sapiens]
Length = 595
Score = 235 bits (599), Expect = 8e-62
Identities = 137/347 (39%), Positives = 192/347 (55%), Gaps = 23/347 (6%)
Query: 23 SALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIITKV 82
S ++ YET KV +++ G + ++I Y V + + K YQ E SS+ TKV
Sbjct: 8 SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEP-VISSVHTKV 65
Query: 83 KGITTSE------------HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIR 130
KGI + H V+D +Y P +G S F ++T T Q Q CPE
Sbjct: 66 KGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFF-VMTNFLKTEGQEQRLCPE-YP 123
Query: 131 VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLG 189
C SD C G +D G++TGRCV Y+G KTCEV WCP+E + L
Sbjct: 124 TRRTLCSSDRGCKKGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALL 182
Query: 190 TMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAG 249
A NFT+LIKN+I +P +++ NI G CTFH+ + CPIF+LG I + G
Sbjct: 183 NSAENFTVLIKNNIDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETG 239
Query: 250 ESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYY 307
++F+++A +GG++G+ I WDC+LD C PKYSFRRLD K +V GYNFR+AKYY
Sbjct: 240 DNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYY 299
Query: 308 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV 354
K N RTLIK +GIR D++V G GKF +I ++ + + L+ G+
Sbjct: 300 KENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGL 346
>gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]
Length = 178
Score = 148 bits (373), Expect = 1e-35
Identities = 68/166 (40%), Positives = 109/166 (65%), Gaps = 5/166 (3%)
Query: 19 RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78
+G +L+DY+T K ++ +N+++G+LYR +Q IL Y V +VF+++K YQ+ +T +S++
Sbjct: 7 KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
Query: 79 ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133
ITKVKG+ TS+ ++WDV +YV P +G +VF ++T + T +Q Q C E+ + +
Sbjct: 67 ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
Query: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVE 179
C D+DC AGE GNG++TGRC+ TCE+F WCP+E
Sbjct: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLE 172
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 38.1 bits (87), Expect = 0.019
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 18/90 (20%)
Query: 410 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 469
PS PS S P P PG PP+ Q G + ++ GPA PP +P ++
Sbjct: 296 PSLPSPSKPPI-------QQPTPG--------KPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 470 PSEQM---VDTPASEPAQASTPTDPKGLAQ 496
P Q V P P P P G A+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Score = 30.8 bits (68), Expect = 3.0
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 27/103 (26%)
Query: 410 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 469
P+ PSG L + L Q P + P P G GPA PP +
Sbjct: 332 PAQPSG-----LTKPLAQQP------GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 470 PSEQMVD------------TPASEPAQASTPTD----PKGLAQ 496
PS + TPA +P A PT PK LAQ
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Score = 29.6 bits (65), Expect = 6.6
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 5/72 (6%)
Query: 426 GQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFP-PLRPCPISAPSEQMVDTPASEPAQ 484
G A P P + PS G + GPA P P +P PS+Q P S
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ----PGSAKPS 540
Query: 485 ASTPTDPKGLAQ 496
A P+ K AQ
Sbjct: 541 AQQPSPAKPSAQ 552
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 38.1 bits (87), Expect = 0.019
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 18/90 (20%)
Query: 410 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 469
PS PS S P P PG PP+ Q G + ++ GPA PP +P ++
Sbjct: 296 PSLPSPSKPPI-------QQPTPG--------KPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 470 PSEQM---VDTPASEPAQASTPTDPKGLAQ 496
P Q V P P P P G A+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Score = 30.8 bits (68), Expect = 3.0
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 27/103 (26%)
Query: 410 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 469
P+ PSG L + L Q P + P P G GPA PP +
Sbjct: 332 PAQPSG-----LTKPLAQQP------GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 470 PSEQMVD------------TPASEPAQASTPTD----PKGLAQ 496
PS + TPA +P A PT PK LAQ
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Score = 29.6 bits (65), Expect = 6.6
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 5/72 (6%)
Query: 426 GQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFP-PLRPCPISAPSEQMVDTPASEPAQ 484
G A P P + PS G + GPA P P +P PS+Q P S
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ----PGSAKPS 540
Query: 485 ASTPTDPKGLAQ 496
A P+ K AQ
Sbjct: 541 AQQPSPAKPSAQ 552
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 37.0 bits (84), Expect = 0.041
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 410 PSHPSGSWPVTLARVLGQ---APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 466
P + +G P TL R + + APP+PG + P P GQ ++ P+ P P
Sbjct: 618 PHNAAGPSPHTLRRAVKKPAPAPPKPG----NPPPGHPGGQSSSGTSQHPPSLSPKPPTR 673
Query: 467 ISAPSEQMVDTPASEPAQASTPTDPK 492
+P Q P +P+ S + P+
Sbjct: 674 SPSPPTQHTGQPPGQPSAPSQLSAPR 699
Score = 32.0 bits (71), Expect = 1.3
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 15/87 (17%)
Query: 410 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 469
P HP G + Q PP + + PSPP+ GQ P P P +SA
Sbjct: 648 PGHPGGQ----SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ------PPGQPSAPSQLSA 697
Query: 470 P-----SEQMVDTPASEPAQASTPTDP 491
P S + P P Q T P
Sbjct: 698 PRRYSSSLSPIQAPNHPPPQPPTQATP 724
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 37.0 bits (84), Expect = 0.041
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 410 PSHPSGSWPVTLARVLGQ---APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 466
P + +G P TL R + + APP+PG + P P GQ ++ P+ P P
Sbjct: 540 PHNAAGPSPHTLRRAVKKPAPAPPKPG----NPPPGHPGGQSSSGTSQHPPSLSPKPPTR 595
Query: 467 ISAPSEQMVDTPASEPAQASTPTDPK 492
+P Q P +P+ S + P+
Sbjct: 596 SPSPPTQHTGQPPGQPSAPSQLSAPR 621
Score = 32.0 bits (71), Expect = 1.3
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 15/87 (17%)
Query: 410 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 469
P HP G + Q PP + + PSPP+ GQ P P P +SA
Sbjct: 570 PGHPGGQ----SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ------PPGQPSAPSQLSA 619
Query: 470 P-----SEQMVDTPASEPAQASTPTDP 491
P S + P P Q T P
Sbjct: 620 PRRYSSSLSPIQAPNHPPPQPPTQATP 646
>gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]
Length = 1273
Score = 36.6 bits (83), Expect = 0.054
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 431 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 488
+P + QHPS PS Q A+ P PP + +S PS+ TPAS+ P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271
>gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens]
Length = 1273
Score = 36.6 bits (83), Expect = 0.054
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 431 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 488
+P + QHPS PS Q A+ P PP + +S PS+ TPAS+ P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271
>gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens]
Length = 1273
Score = 36.6 bits (83), Expect = 0.054
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 431 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 488
+P + QHPS PS Q A+ P PP + +S PS+ TPAS+ P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271
>gi|215820652 StAR-related lipid transfer (START) domain containing
8 isoform b [Homo sapiens]
Length = 1023
Score = 36.6 bits (83), Expect = 0.054
Identities = 37/140 (26%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 351 SVGVVRNPLWGPSGCGGSTRPLHTGL-CWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCT 409
S G R W + GGS WP SF ++ ++H+ V
Sbjct: 173 SAGFYRAKNWAATSAGGSGANTRKAWEAWPVASF-----------RHPQWTHRGDCLVHV 221
Query: 410 PS-HPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECG------------ 456
P H G++P +L+ + PE GHR D P G EG++G+ CG
Sbjct: 222 PGDHKPGTFPRSLS--IESLCPEDGHRLADWQPGRRWGCEGRRGS-CGSTGSHASTYDNL 278
Query: 457 PAFPPLRPCPISAPSEQMVD 476
P P P + A +E D
Sbjct: 279 PELYPAEPVMVGAEAEDEDD 298
>gi|215820650 StAR-related lipid transfer (START) domain containing
8 isoform a [Homo sapiens]
Length = 1103
Score = 36.6 bits (83), Expect = 0.054
Identities = 37/140 (26%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 351 SVGVVRNPLWGPSGCGGSTRPLHTGL-CWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCT 409
S G R W + GGS WP SF ++ ++H+ V
Sbjct: 253 SAGFYRAKNWAATSAGGSGANTRKAWEAWPVASF-----------RHPQWTHRGDCLVHV 301
Query: 410 PS-HPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECG------------ 456
P H G++P +L+ + PE GHR D P G EG++G+ CG
Sbjct: 302 PGDHKPGTFPRSLS--IESLCPEDGHRLADWQPGRRWGCEGRRGS-CGSTGSHASTYDNL 358
Query: 457 PAFPPLRPCPISAPSEQMVD 476
P P P + A +E D
Sbjct: 359 PELYPAEPVMVGAEAEDEDD 378
>gi|31543659 StAR-related lipid transfer (START) domain containing 8
isoform b [Homo sapiens]
Length = 1023
Score = 36.6 bits (83), Expect = 0.054
Identities = 37/140 (26%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 351 SVGVVRNPLWGPSGCGGSTRPLHTGL-CWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCT 409
S G R W + GGS WP SF ++ ++H+ V
Sbjct: 173 SAGFYRAKNWAATSAGGSGANTRKAWEAWPVASF-----------RHPQWTHRGDCLVHV 221
Query: 410 PS-HPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECG------------ 456
P H G++P +L+ + PE GHR D P G EG++G+ CG
Sbjct: 222 PGDHKPGTFPRSLS--IESLCPEDGHRLADWQPGRRWGCEGRRGS-CGSTGSHASTYDNL 278
Query: 457 PAFPPLRPCPISAPSEQMVD 476
P P P + A +E D
Sbjct: 279 PELYPAEPVMVGAEAEDEDD 298
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 36.2 bits (82), Expect = 0.071
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 11/78 (14%)
Query: 429 PPEPGHRSEDQHPSPPS--GQEGQQGAECGPA-----FPPLRPCPISAP---SEQMVDTP 478
PP+P + + Q P PP+ G EG A C P P L P P E+ +
Sbjct: 522 PPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPS 581
Query: 479 ASEPAQASTPT-DPKGLA 495
+ +Q+ TPT PKGLA
Sbjct: 582 SGYSSQSGTPTLPPKGLA 599
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 35.8 bits (81), Expect = 0.092
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 5/86 (5%)
Query: 407 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 465
V P P S PV+ A QAPP PSPP+ A P PP
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 728
Query: 466 PISAPSEQMVDTPASEPAQASTPTDP 491
P++AP Q+ +P + P + + T P
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPP 754
Score = 29.3 bits (64), Expect = 8.7
Identities = 27/88 (30%), Positives = 31/88 (35%), Gaps = 3/88 (3%)
Query: 410 PSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC-PI 467
P P S P++ A QAPP PSPP+ A P PPL P+
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766
Query: 468 SAPSEQMVDTPASEPAQASTPTDPKGLA 495
P P S P P P LA
Sbjct: 767 QVPPSPPASLPMS-PLAKPPPQAPPALA 793
>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
Length = 1337
Score = 35.8 bits (81), Expect = 0.092
Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 19/79 (24%)
Query: 410 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 469
P PS P+ + PP P H+ P PP C P PP PCP +
Sbjct: 84 PMPPSAQGPLPPCPI---RPPFPNHQMRHPFPVPP----------CFPPMPPPMPCPNNP 130
Query: 470 PSEQMVDTPASEPAQASTP 488
P P + P Q + P
Sbjct: 131 P------VPGAPPGQGTFP 143
>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
Length = 1374
Score = 35.8 bits (81), Expect = 0.092
Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 19/79 (24%)
Query: 410 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 469
P PS P+ + PP P H+ P PP C P PP PCP +
Sbjct: 84 PMPPSAQGPLPPCPI---RPPFPNHQMRHPFPVPP----------CFPPMPPPMPCPNNP 130
Query: 470 PSEQMVDTPASEPAQASTP 488
P P + P Q + P
Sbjct: 131 P------VPGAPPGQGTFP 143
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 35.4 bits (80), Expect = 0.12
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 407 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 465
V P P S PV+ A QAPP PSPP+ A P PP
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 503
Query: 466 PISAPSEQMVDTPASEPAQASTP 488
P++AP Q+ P P +TP
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATP 526
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,155,088
Number of Sequences: 37866
Number of extensions: 1144193
Number of successful extensions: 5629
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 152
Number of HSP's that attempted gapping in prelim test: 5181
Number of HSP's gapped (non-prelim): 525
length of query: 497
length of database: 18,247,518
effective HSP length: 106
effective length of query: 391
effective length of database: 14,233,722
effective search space: 5565385302
effective search space used: 5565385302
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.