Search of human proteins with 24797095

Search of human proteins with 24797095

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24797095 pyrroline-5-carboxylate reductase 1 isoform 2 [Homo
sapiens]
         (316 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24797095 pyrroline-5-carboxylate reductase 1 isoform 2 [Homo ...   613   e-176
gi|24797097 pyrroline-5-carboxylate reductase 1 isoform 1 [Homo ...   563   e-161
gi|21361454 pyrroline-5-carboxylate reductase family, member 2 [...   500   e-142
gi|198041662 pyrroline-5-carboxylate reductase-like [Homo sapiens]    227   9e-60
gi|164698426 hypothetical protein LOC122945 isoform 1 [Homo sapi...    52   7e-07
gi|20302040 hypothetical protein LOC122945 isoform 2 [Homo sapiens]    52   7e-07
gi|47578107 delangin isoform B [Homo sapiens]                          31   1.6  
gi|47578105 delangin isoform A [Homo sapiens]                          31   1.6  
gi|76880486 activating signal cointegrator 1 complex subunit 3 i...    30   2.1  
gi|156627571 sorbitol dehydrogenase [Homo sapiens]                     30   3.7  
gi|54607135 translocase of outer mitochondrial membrane 70 homol...    30   3.7  
gi|153791707 sorting nexin family member 30 [Homo sapiens]             29   6.2  
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]                    29   6.2  
gi|134152667 ICBP90 binding protein 1 [Homo sapiens]                   28   8.2  

>gi|24797095 pyrroline-5-carboxylate reductase 1 isoform 2 [Homo
           sapiens]
          Length = 316

 Score =  613 bits (1581), Expect = e-176
 Identities = 316/316 (100%), Positives = 316/316 (100%)

Query: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60
           MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
Sbjct: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60

Query: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120
           QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
Sbjct: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120

Query: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180
           MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
Sbjct: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180

Query: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240
           AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
Sbjct: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240

Query: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLELGSPE 300
           ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLELGSPE
Sbjct: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLELGSPE 300

Query: 301 GLHPLLLQYQLARAPS 316
           GLHPLLLQYQLARAPS
Sbjct: 301 GLHPLLLQYQLARAPS 316


>gi|24797097 pyrroline-5-carboxylate reductase 1 isoform 1 [Homo
           sapiens]
          Length = 319

 Score =  563 bits (1451), Expect = e-161
 Identities = 300/317 (94%), Positives = 300/317 (94%), Gaps = 4/317 (1%)

Query: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60
           MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
Sbjct: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60

Query: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120
           QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
Sbjct: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120

Query: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180
           MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
Sbjct: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180

Query: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240
           AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
Sbjct: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240

Query: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLELG--- 297
           ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDK  L    G   
Sbjct: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL 300

Query: 298 SPEGLHPLLLQYQLARA 314
           SP G H  LL   LA A
Sbjct: 301 SPSG-HTKLLPRSLAPA 316


>gi|21361454 pyrroline-5-carboxylate reductase family, member 2
           [Homo sapiens]
          Length = 320

 Score =  500 bits (1288), Expect = e-142
 Identities = 253/289 (87%), Positives = 277/289 (95%)

Query: 1   MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 60
           MSVGFIGAGQLA+ALA+GFTAAG+L+AHKI+ASSP+M+L TVSALRKMGV LT  NKETV
Sbjct: 1   MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETV 60

Query: 61  QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC 120
           +HSDVLFLAVKPHIIPFILDEIGAD++ RHIVVSCAAGVTISS+EKKL AF+PAP+VIRC
Sbjct: 61  KHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRC 120

Query: 121 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY 180
           MTNTPVVV+EGATVYATGTHA VEDG+L+EQL+SSVGFCTEVEEDLIDAVTGLSGSGPAY
Sbjct: 121 MTNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAY 180

Query: 181 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH 240
           AF ALDALADGGVKMGLPRRLA++LGAQALLGAAKMLL SEQHP QLKDNV SPGGATIH
Sbjct: 181 AFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIH 240

Query: 241 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDK 289
           ALH LESGGFRSLLINAVEASCIRTRELQSMADQE++SPAA+KKT+LD+
Sbjct: 241 ALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDR 289


>gi|198041662 pyrroline-5-carboxylate reductase-like [Homo sapiens]
          Length = 286

 Score =  227 bits (579), Expect = 9e-60
 Identities = 124/267 (46%), Positives = 172/267 (64%), Gaps = 7/267 (2%)

Query: 3   VGFIGAGQLAFALAKGFTAAGVLAAHKIMASSP-DMDLATVSALRKMGVKLTPHNKETVQ 61
           VGF+GAG++A A+A+G   AG + A  I+AS+P D +L    AL   G + T  N+E +Q
Sbjct: 23  VGFVGAGRMAGAIAQGLIRAGKVEAQHILASAPTDRNLCHFQAL---GCRTTHSNQEVLQ 79

Query: 62  HSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCM 121
              ++  A KPH++P +L E+   +   HI+VS AAGV++S++E+ L    P  RV+R +
Sbjct: 80  SCLLVIFATKPHVLPAVLAEVAPVVTTEHILVSVAAGVSLSTLEELLP---PNTRVLRVL 136

Query: 122 TNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYA 181
            N P VV+EGA V A G H    + +L++ LL + G C EV E  +D  TGLSGSG A+ 
Sbjct: 137 PNLPCVVQEGAIVMARGRHVGSSETKLLQHLLEACGRCEEVPEAYVDIHTGLSGSGVAFV 196

Query: 182 FTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHA 241
               +ALA+G VKMG+P  LA R+ AQ LLG AKMLLH  QHP QL+ +V +PGG TI+ 
Sbjct: 197 CAFSEALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYG 256

Query: 242 LHVLESGGFRSLLINAVEASCIRTREL 268
           LH LE GG R+  ++AVEA+  R +EL
Sbjct: 257 LHALEQGGLRAATMSAVEAATCRAKEL 283


>gi|164698426 hypothetical protein LOC122945 isoform 1 [Homo
           sapiens]
          Length = 359

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 2/107 (1%)

Query: 3   VGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQH 62
           VG IG G L   LA      G + A  +  S+   +  T+  L+K+G+K   HN + V  
Sbjct: 79  VGIIGGGHLGKQLAGTLLQLGPIPAESLRISTRRPE--TLGELQKLGIKCFYHNADLVSW 136

Query: 63  SDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLS 109
           +DV+FL   P  +P I  EI   +E   IV S  A + +  ++  L+
Sbjct: 137 ADVIFLCCLPSQLPNICVEIYTSLEKASIVYSFVAAIPLPRLKLLLN 183


>gi|20302040 hypothetical protein LOC122945 isoform 2 [Homo sapiens]
          Length = 250

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 2/107 (1%)

Query: 3   VGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQH 62
           VG IG G L   LA      G + A  +  S+   +  T+  L+K+G+K   HN + V  
Sbjct: 79  VGIIGGGHLGKQLAGTLLQLGPIPAESLRISTRRPE--TLGELQKLGIKCFYHNADLVSW 136

Query: 63  SDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLS 109
           +DV+FL   P  +P I  EI   +E   IV S  A + +  ++  L+
Sbjct: 137 ADVIFLCCLPSQLPNICVEIYTSLEKASIVYSFVAAIPLPRLKLLLN 183


>gi|47578107 delangin isoform B [Homo sapiens]
          Length = 2697

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 6/70 (8%)

Query: 251 RSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLE--LGS--PEGLHPLL 306
           +SLL NA  A  +    L +  D   VS        +  DH+ L+  LGS  PEG  P+L
Sbjct: 38  KSLLFNARIAEEVNC--LLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVL 95

Query: 307 LQYQLARAPS 316
           LQ  LAR+P+
Sbjct: 96  LQAVLARSPN 105


>gi|47578105 delangin isoform A [Homo sapiens]
          Length = 2804

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 6/70 (8%)

Query: 251 RSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLE--LGS--PEGLHPLL 306
           +SLL NA  A  +    L +  D   VS        +  DH+ L+  LGS  PEG  P+L
Sbjct: 38  KSLLFNARIAEEVNC--LLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVL 95

Query: 307 LQYQLARAPS 316
           LQ  LAR+P+
Sbjct: 96  LQAVLARSPN 105


>gi|76880486 activating signal cointegrator 1 complex subunit 3
           isoform a [Homo sapiens]
          Length = 2202

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 22/77 (28%), Positives = 32/77 (41%)

Query: 36  DMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSC 95
           DM L+    LR   +  TP   + V    V  +A+   +   ILDE+    EDR  V+  
Sbjct: 567 DMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPVLES 626

Query: 96  AAGVTISSIEKKLSAFR 112
               T+  +E   S  R
Sbjct: 627 IVARTLRQVESTQSMIR 643


>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
          Length = 357

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 32/136 (23%), Positives = 51/136 (37%), Gaps = 7/136 (5%)

Query: 107 KLSAFRPAPRVIRCMTNTP------VVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCT 160
           K+  +  +P +  C T               A  Y    +   E+G L+E L   +  C 
Sbjct: 107 KMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACR 166

Query: 161 EVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHS 220
                L   V  + G+GP    T L A A G  ++ +    A RL     +GA  +L  S
Sbjct: 167 RGGVTLGHKVL-VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQIS 225

Query: 221 EQHPGQLKDNVSSPGG 236
           ++ P ++   V    G
Sbjct: 226 KESPQEIARKVEGQLG 241


>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
           A [Homo sapiens]
          Length = 608

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 25/62 (40%), Positives = 31/62 (50%), Gaps = 7/62 (11%)

Query: 162 VEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPR-RLAVRLGAQALLGAAKMLLHS 220
           VE  ++ A    SGSG     TA      G    GLPR +LA+ +GA  LLGA  + L S
Sbjct: 7   VEAAVVAAAVPSSGSGVGGGGTA------GPGTGGLPRWQLALAVGAPLLLGAGAIYLWS 60

Query: 221 EQ 222
            Q
Sbjct: 61  RQ 62


>gi|153791707 sorting nexin family member 30 [Homo sapiens]
          Length = 437

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 96  AAGVTISSIEKKLSAF-RPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLS 154
           A G  + +   KL    R A R+I+      V +RE   VY+T +  + E    +E + +
Sbjct: 244 AIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSA 303

Query: 155 SVGFCTEVEEDLIDAVT 171
            +G C+   E+L D +T
Sbjct: 304 CIGNCSTALEELTDDMT 320


>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
          Length = 1858

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 3/72 (4%)

Query: 240 HALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLELGSP 299
           H + +LE+ G     +N + +  I+  ELQ    ++Q++ A I   +L+K  L   +  P
Sbjct: 531 HVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL---VSQP 587

Query: 300 EGLHPLLLQYQL 311
            G    L+ Y L
Sbjct: 588 LGQSNFLIFYLL 599


>gi|134152667 ICBP90 binding protein 1 [Homo sapiens]
          Length = 1440

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 40/160 (25%), Positives = 64/160 (40%), Gaps = 27/160 (16%)

Query: 150 EQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQA 209
           E  L S+   TEV E L +  +G+   GP    T L+ +AD  + +  P  + VRL    
Sbjct: 778 EHDLKSLSGLTEVMEILKEGSSGMDNKGP---LTELEDVADVHMLVHSPAHVRVRLDHYQ 834

Query: 210 LLGAAKMLLHSEQHPGQLKDNVSSPGGATIH----ALHVL-------------------E 246
            L   ++    ++   QL  +  S  G+ +      + VL                   +
Sbjct: 835 YLALLRLKEVLQRLQEQLTKDTESMTGSPLQNQTACIGVLFPSAEVALLMHPAPGAVDAD 894

Query: 247 SGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTI 286
           S G  S  +   E S    REL+S A  +Q  PA+ +K +
Sbjct: 895 SAGSDSTSLVDSELSPSEDRELKSDASSDQ-GPASPEKVL 933


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,463,697
Number of Sequences: 37866
Number of extensions: 489697
Number of successful extensions: 1059
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1046
Number of HSP's gapped (non-prelim): 17
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.