Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 24308219
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308219 synaptotagmin IV [Homo sapiens]
(425 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308219 synaptotagmin IV [Homo sapiens] 852 0.0
gi|216548478 synaptotagmin XI [Homo sapiens] 446 e-125
gi|38570146 synaptotagmin VII [Homo sapiens] 233 3e-61
gi|45504376 synaptotagmin VI [Homo sapiens] 230 2e-60
gi|211059429 synaptotagmin II [Homo sapiens] 227 1e-59
gi|31543670 synaptotagmin II [Homo sapiens] 227 1e-59
gi|92859638 synaptotagmin V [Homo sapiens] 225 7e-59
gi|39752671 synaptotagmin X [Homo sapiens] 224 9e-59
gi|209447073 synaptotagmin I [Homo sapiens] 222 4e-58
gi|5032139 synaptotagmin I [Homo sapiens] 222 4e-58
gi|209447070 synaptotagmin I [Homo sapiens] 222 4e-58
gi|28376627 synaptotagmin IX [Homo sapiens] 216 3e-56
gi|238550198 synaptotagmin III [Homo sapiens] 198 9e-51
gi|238550196 synaptotagmin III [Homo sapiens] 198 9e-51
gi|14150054 synaptotagmin III [Homo sapiens] 198 9e-51
gi|40068038 B/K protein [Homo sapiens] 168 1e-41
gi|6005997 double C2-like domains, beta [Homo sapiens] 165 8e-41
gi|47078261 double C2-like domains, alpha [Homo sapiens] 150 2e-36
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 148 8e-36
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 148 8e-36
gi|29366828 synaptotagmin XII [Homo sapiens] 143 3e-34
gi|94536846 synaptotagmin VIII [Homo sapiens] 138 1e-32
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 137 1e-32
gi|123173752 synaptotagmin XIV-like [Homo sapiens] 114 2e-25
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 113 3e-25
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 113 3e-25
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 113 4e-25
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 110 2e-24
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 110 2e-24
gi|24308233 synaptotagmin XIII [Homo sapiens] 110 2e-24
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 852 bits (2201), Expect = 0.0
Identities = 425/425 (100%), Positives = 425/425 (100%)
Query: 1 MAPITTSREEFDEIPTVVGIFSAFGLVFTVSLFAWICCQRKSSKSNKTPPYKFVHVLKGV 60
MAPITTSREEFDEIPTVVGIFSAFGLVFTVSLFAWICCQRKSSKSNKTPPYKFVHVLKGV
Sbjct: 1 MAPITTSREEFDEIPTVVGIFSAFGLVFTVSLFAWICCQRKSSKSNKTPPYKFVHVLKGV 60
Query: 61 DIYPENLNSKKKFGADDKNEVKNKPAVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDLEN 120
DIYPENLNSKKKFGADDKNEVKNKPAVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDLEN
Sbjct: 61 DIYPENLNSKKKFGADDKNEVKNKPAVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDLEN 120
Query: 121 ATPKLFLEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGL 180
ATPKLFLEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGL
Sbjct: 121 ATPKLFLEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGL 180
Query: 181 PAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHF 240
PAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHF
Sbjct: 181 PAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHF 240
Query: 241 TILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQST 300
TILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQST
Sbjct: 241 TILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQST 300
Query: 301 TNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVF 360
TNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVF
Sbjct: 301 TNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVF 360
Query: 361 DIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWH 420
DIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWH
Sbjct: 361 DIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWH 420
Query: 421 VLCDG 425
VLCDG
Sbjct: 421 VLCDG 425
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 446 bits (1147), Expect = e-125
Identities = 228/432 (52%), Positives = 307/432 (71%), Gaps = 10/432 (2%)
Query: 1 MAPITTSREEFDEIPTVVGIFSAFGLVFTVSL--FAWICCQRKSSKSNKTPPYKFVHVLK 58
MA IT R FD P V G+ A LV VS+ F W CC +++ K K PPYKF+H+LK
Sbjct: 1 MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK 60
Query: 59 GVDIYPENLNSKKKFGADDKNEVKNKPAVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDL 118
G+ IYPE L++KKK +++ + +L +D + L K P S S +
Sbjct: 61 GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSR-DKDPRGPSSGSCI 119
Query: 119 ENATPKLF----LEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNI 174
+ K+ L S++P K+ TS +S E+ LG+L FS++YNF +KA VV I
Sbjct: 120 DQLPIKMDYGEELRSPITSLTPGESKT-TSPSSPEEDVMLGSLTFSVDYNFPKKALVVTI 178
Query: 175 KEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQ 234
+EA GLP MD+Q+ SDPYIKMTILP+K+H+VKTRVLRKTLDP FDETFTFYGIPY+Q+Q
Sbjct: 179 QEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQ 238
Query: 235 ELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLIS 294
+L LHF +LSFDRFSRDD+IGEV++PL+G++ S GK+ + R+IIKRN++K RGEL +S
Sbjct: 239 DLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVS 298
Query: 295 LCYQSTTNTLTVVVLKARHLPKSDVSGLS-DPYVKVNLYHAKKRISKKKTHVKKCTPNAV 353
L YQ +TVVVLKARHLPK D++GLS +PYVKVN+Y+ +KRI+KKKTHVKKCT N +
Sbjct: 299 LSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPI 358
Query: 354 FNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGA-AAEGTGGEHWKEICDYP 412
FNE F++DIP + L DIS+EFLV+D +R ++NEV+G+L+LGA + +G EHW+E+C+ P
Sbjct: 359 FNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESP 418
Query: 413 RRQIAKWHVLCD 424
R+ +AKWH L +
Sbjct: 419 RKPVAKWHSLSE 430
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 233 bits (593), Expect = 3e-61
Identities = 136/360 (37%), Positives = 207/360 (57%), Gaps = 14/360 (3%)
Query: 68 NSKKKFGADDKNEVKNKPAVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDLENATPKLFL 127
NS + G D +++ K ++ L + +N P P SD P+ +
Sbjct: 51 NSLETVGTPDSGRGRSE----KKAIKLPAGGKAVN-TAPVPGQTPHDESD-RRTEPRSSV 104
Query: 128 EGEKESVSPESLKSSTSLTSEE-----KQEKLGTLFFSLEYNFERKAFVVNIKEARGLPA 182
S++ E L S +E +E LG + FS+ YNF+ V I +A+ LPA
Sbjct: 105 SDLVNSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPA 164
Query: 183 MDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTI 242
D S TSDP++K+ +LP+KKHK++T+V RK L+P ++ETF F G PY ++ + L+ +
Sbjct: 165 KDF-SGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQV 223
Query: 243 LSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTN 302
L +DRFSR+D IGEV IPL+ ++L++ + +K S RGELL+SLCY + N
Sbjct: 224 LDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKD--LKPCSDGSGSRGELLLSLCYNPSAN 281
Query: 303 TLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDI 362
++ V ++KAR+L D+ G SDPYVKV L + KR+ KKKT K N +FNE F FDI
Sbjct: 282 SIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDI 341
Query: 363 PCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422
P E L + ++ V+D ++ SRN+VIG++ L + +HWK++ PR+ +A+WH L
Sbjct: 342 PTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQL 401
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 230 bits (587), Expect = 2e-60
Identities = 127/314 (40%), Positives = 190/314 (60%), Gaps = 20/314 (6%)
Query: 115 PSDLENATPKLFLEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNI 174
P+ + P+L+ +++SV E KS E + G + FSL Y++E + +V I
Sbjct: 116 PTSIGRIKPELY---KQKSVDGEDAKS-------EATKSCGKINFSLRYDYETETLIVRI 165
Query: 175 KEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQ 234
+A LPA D +SDPY+K+ +LP++K K++TRV RKTL+P FDE F F +PY ++
Sbjct: 166 LKAFDLPAKDFCG-SSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHF-PVPYEELA 223
Query: 235 ELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGR----GE 290
+ LH ++ FDRFSR D+IGEV++ L E L I ++++ ++ GE
Sbjct: 224 DRKLHLSVFDFDRFSRHDMIGEVILD----NLFEASDLSRETSIWKDIQYATSESVDLGE 279
Query: 291 LLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTP 350
++ SLCY T LT+ V+K R+L D++G SDPYVKV+L +R+ KKKT +KK T
Sbjct: 280 IMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTL 339
Query: 351 NAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICD 410
N V+NE +FDIP E ++ +S+ V+D +R NE+IG +G AEG G +HW E+
Sbjct: 340 NPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLA 399
Query: 411 YPRRQIAKWHVLCD 424
YPR+ IA WH L +
Sbjct: 400 YPRKPIAHWHSLVE 413
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 227 bits (579), Expect = 1e-59
Identities = 127/295 (43%), Positives = 182/295 (61%), Gaps = 4/295 (1%)
Query: 129 GEKESVSPESLKSSTSLTSEEKQ-EKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187
G+ + + L EEK+ E LG L FSL+Y+F+ V + +A LPA+D
Sbjct: 114 GQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALD-MG 172
Query: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247
TSDPY+K+ +LP+KK K +T+V RKTL+PAF+ETFTF +PY ++ L I FDR
Sbjct: 173 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDR 231
Query: 248 FSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVV 307
FS+ DIIGEV +P++ ++L + + R++ + G++ SL Y T LTV
Sbjct: 232 FSKHDIIGEVKVPMNTVDLGQ-PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVC 290
Query: 308 VLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGL 367
+L+A++L K DV GLSDPYVK++L KR+ KKKT VKK T N FNE F F+IP E +
Sbjct: 291 ILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQI 350
Query: 368 EDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422
+ + V VLD ++ +NE IG++ +G+ A GT HW ++ PRR IA+WH L
Sbjct: 351 QKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 227 bits (579), Expect = 1e-59
Identities = 127/295 (43%), Positives = 182/295 (61%), Gaps = 4/295 (1%)
Query: 129 GEKESVSPESLKSSTSLTSEEKQ-EKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187
G+ + + L EEK+ E LG L FSL+Y+F+ V + +A LPA+D
Sbjct: 114 GQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALD-MG 172
Query: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247
TSDPY+K+ +LP+KK K +T+V RKTL+PAF+ETFTF +PY ++ L I FDR
Sbjct: 173 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDR 231
Query: 248 FSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVV 307
FS+ DIIGEV +P++ ++L + + R++ + G++ SL Y T LTV
Sbjct: 232 FSKHDIIGEVKVPMNTVDLGQ-PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVC 290
Query: 308 VLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGL 367
+L+A++L K DV GLSDPYVK++L KR+ KKKT VKK T N FNE F F+IP E +
Sbjct: 291 ILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQI 350
Query: 368 EDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422
+ + V VLD ++ +NE IG++ +G+ A GT HW ++ PRR IA+WH L
Sbjct: 351 QKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 225 bits (573), Expect = 7e-59
Identities = 121/295 (41%), Positives = 183/295 (62%), Gaps = 5/295 (1%)
Query: 130 EKESVSPESLKSSTSLTSEEKQEK--LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187
+K E L+ + S ++ +K LG L +SL+Y+F+ +V I +A GL A+D
Sbjct: 83 DKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGG 142
Query: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247
+SDPY+++ +LP+K+ + +T+V R+TL+P F ETF F +PY ++ L + FDR
Sbjct: 143 -SSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDR 200
Query: 248 FSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVV 307
FSR+D IGEV +P+S ++L RE+ + G++ SL Y T LTV+
Sbjct: 201 FSRNDAIGEVRVPMSSVDLGRPVQAW-RELQAAPREEQEKLGDICFSLRYVPTAGKLTVI 259
Query: 308 VLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGL 367
VL+A++L K DV GLSDPYVKV+L K++ KKKT +KK T N +NE F F++PC+ +
Sbjct: 260 VLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQV 319
Query: 368 EDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422
+ + VE VLD ++ +NE IG++ +GAAA G G HW ++ PRR IA+WH L
Sbjct: 320 QKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSL 374
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 224 bits (572), Expect = 9e-59
Identities = 132/323 (40%), Positives = 185/323 (57%), Gaps = 19/323 (5%)
Query: 114 SPSDLENATPKLFLEGEKES----VSPESLKSSTSLTSEEKQEK----LGTLFFSLEYNF 165
S D T + GE + + PE K S+ SE Q + G L F+L+Y++
Sbjct: 185 SSVDFSMGTEPVLQRGETTTSIGRIKPELYKQK-SVDSEGNQNEDVKICGKLNFTLQYDY 243
Query: 166 ERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTF 225
E + VV I +A LPA D TSDPY+KM +LP++K K +TRV RKTL+P FDETF F
Sbjct: 244 ENELLVVKIIKALDLPAKDFTG-TSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQF 302
Query: 226 YGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVR-- 283
+ Y Q+ LHF++ FDRFSR D+IGEV++ L E L + +++
Sbjct: 303 -PVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILD----NLFEVSDLSREATVWKDIHCA 357
Query: 284 --KSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKK 341
+S GE++ SLCY T +T+ V+K R+L D++G SDPYVKV+L +R+ K+
Sbjct: 358 TTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKR 417
Query: 342 KTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTG 401
KT KK T N V+NE +FDIP E ++ +S+ V+D +R NEVIG G AEG G
Sbjct: 418 KTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLG 477
Query: 402 GEHWKEICDYPRRQIAKWHVLCD 424
+HW E+ Y R+ I WH L +
Sbjct: 478 RDHWNEMLAYHRKPITHWHPLLE 500
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 222 bits (566), Expect = 4e-58
Identities = 126/327 (38%), Positives = 193/327 (59%), Gaps = 12/327 (3%)
Query: 105 FPKTNLKPGSPSDLENATPKLFLEGEKESVSPESLK---SSTSLTSEEK------QEKLG 155
F K N K G +NA ++ +++ ++LK + T LT E+ +EKLG
Sbjct: 85 FKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLG 144
Query: 156 TLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTL 215
L +SL+Y+F+ +V I +A LPA+D TSDPY+K+ +LP+KK K +T+V RKTL
Sbjct: 145 KLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
Query: 216 DPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNR 275
+P F+E FTF +PY+++ L + FDRFS+ DIIGE +P++ ++ R
Sbjct: 204 NPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW-R 261
Query: 276 EIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK 335
++ + G++ SL Y T LTVV+L+A++L K DV GLSDPYVK++L
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
Query: 336 KRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGA 395
KR+ KKKT +KK T N +NE F F++P E ++ + V VLD ++ +N+ IG++ +G
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
Query: 396 AAEGTGGEHWKEICDYPRRQIAKWHVL 422
+ G HW ++ PRR IA+WH L
Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 222 bits (566), Expect = 4e-58
Identities = 126/327 (38%), Positives = 193/327 (59%), Gaps = 12/327 (3%)
Query: 105 FPKTNLKPGSPSDLENATPKLFLEGEKESVSPESLK---SSTSLTSEEK------QEKLG 155
F K N K G +NA ++ +++ ++LK + T LT E+ +EKLG
Sbjct: 85 FKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLG 144
Query: 156 TLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTL 215
L +SL+Y+F+ +V I +A LPA+D TSDPY+K+ +LP+KK K +T+V RKTL
Sbjct: 145 KLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
Query: 216 DPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNR 275
+P F+E FTF +PY+++ L + FDRFS+ DIIGE +P++ ++ R
Sbjct: 204 NPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW-R 261
Query: 276 EIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK 335
++ + G++ SL Y T LTVV+L+A++L K DV GLSDPYVK++L
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
Query: 336 KRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGA 395
KR+ KKKT +KK T N +NE F F++P E ++ + V VLD ++ +N+ IG++ +G
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
Query: 396 AAEGTGGEHWKEICDYPRRQIAKWHVL 422
+ G HW ++ PRR IA+WH L
Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 222 bits (566), Expect = 4e-58
Identities = 126/327 (38%), Positives = 193/327 (59%), Gaps = 12/327 (3%)
Query: 105 FPKTNLKPGSPSDLENATPKLFLEGEKESVSPESLK---SSTSLTSEEK------QEKLG 155
F K N K G +NA ++ +++ ++LK + T LT E+ +EKLG
Sbjct: 85 FKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLG 144
Query: 156 TLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTL 215
L +SL+Y+F+ +V I +A LPA+D TSDPY+K+ +LP+KK K +T+V RKTL
Sbjct: 145 KLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
Query: 216 DPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNR 275
+P F+E FTF +PY+++ L + FDRFS+ DIIGE +P++ ++ R
Sbjct: 204 NPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW-R 261
Query: 276 EIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK 335
++ + G++ SL Y T LTVV+L+A++L K DV GLSDPYVK++L
Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
Query: 336 KRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGA 395
KR+ KKKT +KK T N +NE F F++P E ++ + V VLD ++ +N+ IG++ +G
Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
Query: 396 AAEGTGGEHWKEICDYPRRQIAKWHVL 422
+ G HW ++ PRR IA+WH L
Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 216 bits (550), Expect = 3e-56
Identities = 127/345 (36%), Positives = 197/345 (57%), Gaps = 10/345 (2%)
Query: 81 VKNKPAVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDLENATPKLFLEGEKESVSPESLK 140
V+ + P +S + +R LN + P N++ + ++ + E SL
Sbjct: 154 VQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRI----KPELYKQRSLD 209
Query: 141 SSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILP 200
+ S K G L F L+Y+ + + +V I +A LPA D S TSDPY+K+ +LP
Sbjct: 210 NDDGRRSNSKA--CGKLNFILKYDCDLEQLIVKIHKAVNLPAKDF-SGTSDPYVKIYLLP 266
Query: 201 EKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIP 260
++K K +T+V RKTL+P FDE F F +PY ++ LHF++ FDRFSR D+IG+V++
Sbjct: 267 DRKTKHQTKVHRKTLNPVFDEVFLF-PVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD 325
Query: 261 LSGIELSE-GKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDV 319
++L++ + + + I+ + GEL+ SLCY T LT+ ++KAR+L D+
Sbjct: 326 -HFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDI 384
Query: 320 SGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDS 379
+G SDPYVKV+L +R+ K+KT K+ T N V+NE VFD+P E ++ I + V+D
Sbjct: 385 TGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDY 444
Query: 380 ERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVLCD 424
+R NE+IG +G AE G +HW E+ YPR+ IA WH L +
Sbjct: 445 DRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 198 bits (503), Expect = 9e-51
Identities = 111/273 (40%), Positives = 166/273 (60%), Gaps = 7/273 (2%)
Query: 155 GTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKT 214
G + F+L Y + VV I +A LPA D SDPY+K+ +LP++K K +T+V RKT
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKT 359
Query: 215 LDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGK--ML 272
L+P F+ETF F +P ++ + LHF++ FDRFSR D+IG+V++ + +EL+E
Sbjct: 360 LNPVFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRP 417
Query: 273 MNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLY 332
+ R+I++ K+ GEL SLCY T LTV ++KA +L D++G SDPYVK +L
Sbjct: 418 LWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLI 476
Query: 333 HAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLV 392
+R+ K+KT +KK T N +NE VFD+ E +E++ + V+D + NEVIG
Sbjct: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
Query: 393 LGA-AAEGTGGEHWKEICDYPRRQIAKWHVLCD 424
+G AA+ G EHW E+ PR+ + WH L +
Sbjct: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
Score = 51.2 bits (121), Expect = 2e-06
Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 4/104 (3%)
Query: 154 LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKH--KVKTRVL 211
LG L FSL Y V I +A L AMD SDPY+K +++ E + K KT +
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGF-SDPYVKASLISEGRRLKKRKTSIK 490
Query: 212 RKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIG 255
+ TL+P ++E F P ++ + L ++ +D +++IG
Sbjct: 491 KNTLNPTYNEALVFDVAP-ESVENVGLSIAVVDYDCIGHNEVIG 533
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 198 bits (503), Expect = 9e-51
Identities = 111/273 (40%), Positives = 166/273 (60%), Gaps = 7/273 (2%)
Query: 155 GTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKT 214
G + F+L Y + VV I +A LPA D SDPY+K+ +LP++K K +T+V RKT
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKT 359
Query: 215 LDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGK--ML 272
L+P F+ETF F +P ++ + LHF++ FDRFSR D+IG+V++ + +EL+E
Sbjct: 360 LNPVFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRP 417
Query: 273 MNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLY 332
+ R+I++ K+ GEL SLCY T LTV ++KA +L D++G SDPYVK +L
Sbjct: 418 LWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLI 476
Query: 333 HAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLV 392
+R+ K+KT +KK T N +NE VFD+ E +E++ + V+D + NEVIG
Sbjct: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
Query: 393 LGA-AAEGTGGEHWKEICDYPRRQIAKWHVLCD 424
+G AA+ G EHW E+ PR+ + WH L +
Sbjct: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
Score = 51.2 bits (121), Expect = 2e-06
Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 4/104 (3%)
Query: 154 LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKH--KVKTRVL 211
LG L FSL Y V I +A L AMD SDPY+K +++ E + K KT +
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGF-SDPYVKASLISEGRRLKKRKTSIK 490
Query: 212 RKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIG 255
+ TL+P ++E F P ++ + L ++ +D +++IG
Sbjct: 491 KNTLNPTYNEALVFDVAP-ESVENVGLSIAVVDYDCIGHNEVIG 533
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 198 bits (503), Expect = 9e-51
Identities = 111/273 (40%), Positives = 166/273 (60%), Gaps = 7/273 (2%)
Query: 155 GTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKT 214
G + F+L Y + VV I +A LPA D SDPY+K+ +LP++K K +T+V RKT
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKT 359
Query: 215 LDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGK--ML 272
L+P F+ETF F +P ++ + LHF++ FDRFSR D+IG+V++ + +EL+E
Sbjct: 360 LNPVFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLELAEQPPDRP 417
Query: 273 MNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLY 332
+ R+I++ K+ GEL SLCY T LTV ++KA +L D++G SDPYVK +L
Sbjct: 418 LWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLI 476
Query: 333 HAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLV 392
+R+ K+KT +KK T N +NE VFD+ E +E++ + V+D + NEVIG
Sbjct: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
Query: 393 LGA-AAEGTGGEHWKEICDYPRRQIAKWHVLCD 424
+G AA+ G EHW E+ PR+ + WH L +
Sbjct: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
Score = 51.2 bits (121), Expect = 2e-06
Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 4/104 (3%)
Query: 154 LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKH--KVKTRVL 211
LG L FSL Y V I +A L AMD SDPY+K +++ E + K KT +
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGF-SDPYVKASLISEGRRLKKRKTSIK 490
Query: 212 RKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIG 255
+ TL+P ++E F P ++ + L ++ +D +++IG
Sbjct: 491 KNTLNPTYNEALVFDVAP-ESVENVGLSIAVVDYDCIGHNEVIG 533
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 168 bits (425), Expect = 1e-41
Identities = 106/288 (36%), Positives = 159/288 (55%), Gaps = 12/288 (4%)
Query: 144 SLTSEEKQEK--LGTLFFSLEYNFERKAFVVNIKEARGLPAM-----DEQSMT-SDPYIK 195
SLT EE K LG L FS +Y+ V + EAR LP Q M S+PY+K
Sbjct: 173 SLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVK 232
Query: 196 MTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIG 255
+ +LP++K+ +T V RKT P F+E +TF IP+ + Q L T++ FD+FSR +IG
Sbjct: 233 ICLLPDQKNSKQTGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDFDKFSRHCVIG 291
Query: 256 EVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLP 315
+V +PL ++L +G I + + GELL+SL Y + L V V++A+ L
Sbjct: 292 KVSVPLCEVDLVKGGHWWKALI--PSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLL 349
Query: 316 KSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFL 375
++DVS SDP+VK+ L H K + KKT + T + +NE F F +P E LE+ S+ F
Sbjct: 350 QTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFT 409
Query: 376 VLDSERGSRNEVIGQLVLGAAAEG-TGGEHWKEICDYPRRQIAKWHVL 422
V S N+ IG++V+G + G + HW+ + + R + +WH L
Sbjct: 410 VFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 165 bits (417), Expect = 8e-41
Identities = 101/276 (36%), Positives = 147/276 (53%), Gaps = 8/276 (2%)
Query: 154 LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILP--EKKHKVKTRVL 211
LGTL FSL Y+ E A I +A+GL MD + +DPY+K+ +LP K +K++T+ L
Sbjct: 127 LGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGL-ADPYVKLHLLPGASKANKLRTKTL 185
Query: 212 RKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKM 271
R TL+P ++ET T+YGI + L ++ D+F ++ IGE +PL ++ + K
Sbjct: 186 RNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKT 245
Query: 272 L-----MNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPY 326
+ K + RG +LISL Y S L V +++ HL D +G SDPY
Sbjct: 246 FNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPY 305
Query: 327 VKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNE 386
VK L + SK KT VKK T N FNE F ++I L S+E V D + G N+
Sbjct: 306 VKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSND 365
Query: 387 VIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422
IG +VLG A+G +HW + ++I +WH L
Sbjct: 366 FIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTL 401
Score = 66.6 bits (161), Expect = 4e-11
Identities = 40/116 (34%), Positives = 65/116 (56%), Gaps = 4/116 (3%)
Query: 146 TSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILP--EKK 203
T ++ E+ G + SL+Y+ +++ +V I L AMD SDPY+K + P +KK
Sbjct: 259 TEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGY-SDPYVKTYLRPDVDKK 317
Query: 204 HKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLI 259
K KT V +KTL+P F+E F Y I + + + +L T+ +D +D IG V++
Sbjct: 318 SKHKTAVKKKTLNPEFNEEFC-YEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVL 372
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 150 bits (379), Expect = 2e-36
Identities = 103/319 (32%), Positives = 154/319 (48%), Gaps = 31/319 (9%)
Query: 133 SVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDP 192
+ +PE S S++ LGTL F L Y+ +I A+GL MD + +DP
Sbjct: 70 ATTPEDGAEVDSYDSDDATA-LGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGL-ADP 127
Query: 193 YIKMTILPE--KKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSR 250
Y+K+ +LP K +K+KT+ R TL+P ++E T+ GI I L + D+ S
Sbjct: 128 YVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSH 187
Query: 251 DDIIGEVLIPLSGIELSEGK---MLMNREI------------------IKRNVRKSSG-- 287
++ IGE+ +PL ++ S+ K + + R++ +K + G
Sbjct: 188 NEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQG 247
Query: 288 ----RGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKT 343
RG +L+SL Y S L V +L+ HL DV+G SDPYVK L + SK KT
Sbjct: 248 LLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKT 307
Query: 344 HVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGE 403
VKK T N FNE F ++I L ++E V D + G N+ IG + LG A G +
Sbjct: 308 CVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARK 367
Query: 404 HWKEICDYPRRQIAKWHVL 422
HW + P + +WH L
Sbjct: 368 HWSDCLQQPDAALERWHTL 386
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 148 bits (374), Expect = 8e-36
Identities = 95/313 (30%), Positives = 154/313 (49%), Gaps = 28/313 (8%)
Query: 136 PESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIK 195
PE + + ++ LG L FSL Y+ + + I +A+GL MD + +DPY+K
Sbjct: 375 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGL-ADPYVK 433
Query: 196 MTILP--EKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDI 253
+ +LP K +K++T+ LR T +P ++ET ++GI +Q L ++ D+F ++
Sbjct: 434 LHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEF 493
Query: 254 IGEVLIPLSGIELSE------------------------GKMLMNREIIKRNVRKSSGRG 289
IGE L ++ ++ G L E ++R V RG
Sbjct: 494 IGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER-VGDIEERG 552
Query: 290 ELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCT 349
++L+SL Y + L V +++ HL D +G SDP+VK+ L + +K KT +KK T
Sbjct: 553 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKT 612
Query: 350 PNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEIC 409
N FNE F +DI L S++ V D + G N+ IG LG +A+G +HW E
Sbjct: 613 LNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECL 672
Query: 410 DYPRRQIAKWHVL 422
++I +WH L
Sbjct: 673 KNKDKKIERWHQL 685
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 148 bits (374), Expect = 8e-36
Identities = 95/313 (30%), Positives = 154/313 (49%), Gaps = 28/313 (8%)
Query: 136 PESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIK 195
PE + + ++ LG L FSL Y+ + + I +A+GL MD + +DPY+K
Sbjct: 371 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGL-ADPYVK 429
Query: 196 MTILP--EKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDI 253
+ +LP K +K++T+ LR T +P ++ET ++GI +Q L ++ D+F ++
Sbjct: 430 LHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEF 489
Query: 254 IGEVLIPLSGIELSE------------------------GKMLMNREIIKRNVRKSSGRG 289
IGE L ++ ++ G L E ++R V RG
Sbjct: 490 IGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER-VGDIEERG 548
Query: 290 ELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCT 349
++L+SL Y + L V +++ HL D +G SDP+VK+ L + +K KT +KK T
Sbjct: 549 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKT 608
Query: 350 PNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEIC 409
N FNE F +DI L S++ V D + G N+ IG LG +A+G +HW E
Sbjct: 609 LNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECL 668
Query: 410 DYPRRQIAKWHVL 422
++I +WH L
Sbjct: 669 KNKDKKIERWHQL 681
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 143 bits (360), Expect = 3e-34
Identities = 91/293 (31%), Positives = 161/293 (54%), Gaps = 4/293 (1%)
Query: 131 KESVSPESLKSSTSLTSEEKQE-KLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMT 189
++S S +SL S +S+++ Q+ LG + S+EY+ V + + + L +E S
Sbjct: 129 RKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFE 188
Query: 190 SDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFS 249
S ++++++LP+++ +R+ R FDE F+ P T ++E +L F++ D
Sbjct: 189 SC-FMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDP-TALEEKSLRFSVFGIDEDE 246
Query: 250 RDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVL 309
R+ G V + LS ++L + +N + + GE+L+SL Y T LTVVV+
Sbjct: 247 RNVSTGVVELKLSVLDLPLQPFSGWLYLQDQN-KAADAVGEILLSLSYLPTAERLTVVVV 305
Query: 310 KARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLED 369
KA++L ++ +DP+VKV L +++SKKKT VK+ PN VFNE +F +P L+D
Sbjct: 306 KAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQD 365
Query: 370 ISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422
+S+ V +S R + +G +++G +A G G HW ++ RR ++ WH +
Sbjct: 366 LSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAV 418
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 138 bits (347), Expect = 1e-32
Identities = 98/305 (32%), Positives = 158/305 (51%), Gaps = 23/305 (7%)
Query: 130 EKESVSPESLKSSTSL-----------TSEEKQEKLGTLFFSLEYNFERKAFVVNIKEAR 178
+KESV S + +T+ +S ++ G L SLE++F + V +++A
Sbjct: 83 DKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAA 142
Query: 179 GLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELAL 238
L T DPY ++++ + H+ +T+V R TL P FDET F+ IP ++ L
Sbjct: 143 DL----RPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH-IPQAELPGATL 197
Query: 239 HFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGR-GELLISLCY 297
+ +F RFS + +GE+ +PL ++L +L + ++ + GEL SL Y
Sbjct: 198 QVQLFNFKRFSGHEPLGELRLPLGTVDLQH--VLEHWYLLGPPAATQPEQVGELCFSLRY 255
Query: 298 QSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNEL 357
++ LTVVVL+AR L GL++PYVKV L +++ K+KT KK T FNE
Sbjct: 256 VPSSGRLTVVVLEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEA 311
Query: 358 FVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIA 417
F F +P ++++ + V D R E +G++ LGA A G +HW ++ + RR IA
Sbjct: 312 FTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIA 371
Query: 418 KWHVL 422
+ H L
Sbjct: 372 QRHPL 376
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 137 bits (346), Expect = 1e-32
Identities = 84/273 (30%), Positives = 145/273 (53%), Gaps = 7/273 (2%)
Query: 154 LGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRK 213
LG L+FS+EY E + +V + +A+ L A E T P +K+ +LP+++ ++++ RK
Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSE---TCSPLVKLYLLPDERRFLQSKTKRK 204
Query: 214 TLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIEL-SEGKML 272
T +P FDE F F + I + L F++ DR + ++G+VL PL L + + +
Sbjct: 205 TSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRV 263
Query: 273 MNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLY 332
+ R++ ++ S G+L L Y + LTVVVL+A+ L + G+ +VKV+L
Sbjct: 264 IWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLM 323
Query: 333 HAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLV 392
+ K + KKT + N V+NE F F L+ S+ V+ + G +++ +G++V
Sbjct: 324 NHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVV 383
Query: 393 LG--AAAEGTGGEHWKEICDYPRRQIAKWHVLC 423
+G G EHW E+ P+ + +WH LC
Sbjct: 384 VGPYMYTRGRELEHWDEMLSKPKELVKRWHALC 416
Score = 40.4 bits (93), Expect = 0.003
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 10/142 (7%)
Query: 147 SEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHK- 205
S E + G L F L YN V + A+GL +++ + S ++K++++ K
Sbjct: 272 SLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVS-VFVKVSLMNHNKFVK 330
Query: 206 -VKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIP---- 260
KT + +++P ++ETF+F T++ +L T++ + +G V++
Sbjct: 331 CKKTSAVLGSINPVYNETFSFKA-DATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMY 389
Query: 261 LSGIELSEGKMLMN--REIIKR 280
G EL +++ +E++KR
Sbjct: 390 TRGRELEHWDEMLSKPKELVKR 411
>gi|123173752 synaptotagmin XIV-like [Homo sapiens]
Length = 645
Score = 114 bits (284), Expect = 2e-25
Identities = 83/301 (27%), Positives = 140/301 (46%), Gaps = 27/301 (8%)
Query: 149 EKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKT 208
E K G L EY + V I A+GLP D + S + + +LP KKH+ +T
Sbjct: 346 EPISKCGDLDVIFEYRAASQKLTVTIVRAQGLPDKDRSGVNSWQ-VHVVLLPGKKHRGRT 404
Query: 209 RVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIE--- 265
+ R +P F E TF + + A+ F + + + +R+ ++GE L LS +
Sbjct: 405 NIQRGP-NPVFREKVTFAKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFYLSHLHPEG 463
Query: 266 -------------LSEGKMLMNREIIKRNVRKSS-------GRGELLISLCYQSTTNTLT 305
+S G ++ + + SS G ELL+ L Y +TT L+
Sbjct: 464 EMKVTLVLEPRSNISSGGSPLSPSAVSHSDSTSSTQSLSHGGAPELLVGLSYNATTGRLS 523
Query: 306 VVVLKARHLPKSDVSGLSDPYVKVNLYHAK-KRISKKKTHVKKCTPNAVFNELFVFDIPC 364
V ++K H V+ D Y K+ L ++ + +S+ KT +++ PN V+ E FVF +
Sbjct: 524 VEMIKGSHFRNLAVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQVAL 583
Query: 365 EGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEG-TGGEHWKEICDYPRRQIAKWHVLC 423
L D+++ V + R E+IG + LG + G +HW+E+ + +QI +WH L
Sbjct: 584 FQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEEQDHWEEMKETKGQQICRWHTLL 643
Query: 424 D 424
+
Sbjct: 644 E 644
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 113 bits (283), Expect = 3e-25
Identities = 82/272 (30%), Positives = 134/272 (49%), Gaps = 24/272 (8%)
Query: 155 GTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKH--KVKTRVLR 212
G + FSL+Y + ++ VV++KE L DE S+PY+K +LP+K K KT + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 213 KTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEG--- 269
T++P +DET Y IP + + + L F++ RF R+ +GE I + +L +
Sbjct: 418 DTINPLYDETLR-YEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDH 476
Query: 270 -KMLMNREIIKRNVRKSSGRGELLISLCYQSTTNT----------------LTVVVLKAR 312
L + + S +GEL++SL Y + T L V + +A+
Sbjct: 477 CLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAK 536
Query: 313 HLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFD-IPCEGLEDIS 371
+L + G SD +VK L + + SK+KT V K T N +N FV++ + E L+ +
Sbjct: 537 NLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMC 596
Query: 372 VEFLVLDSERGSRNEVIGQLVLGAAAEGTGGE 403
+E V D E + N+ +G + LG + GE
Sbjct: 597 LELTVWDREPLASNDFLGGVRLGVGTGISNGE 628
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 113 bits (283), Expect = 3e-25
Identities = 82/272 (30%), Positives = 134/272 (49%), Gaps = 24/272 (8%)
Query: 155 GTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKH--KVKTRVLR 212
G + FSL+Y + ++ VV++KE L DE S+PY+K +LP+K K KT + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 213 KTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEG--- 269
T++P +DET Y IP + + + L F++ RF R+ +GE I + +L +
Sbjct: 418 DTINPLYDETLR-YEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDH 476
Query: 270 -KMLMNREIIKRNVRKSSGRGELLISLCYQSTTNT----------------LTVVVLKAR 312
L + + S +GEL++SL Y + T L V + +A+
Sbjct: 477 CLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAK 536
Query: 313 HLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFD-IPCEGLEDIS 371
+L + G SD +VK L + + SK+KT V K T N +N FV++ + E L+ +
Sbjct: 537 NLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMC 596
Query: 372 VEFLVLDSERGSRNEVIGQLVLGAAAEGTGGE 403
+E V D E + N+ +G + LG + GE
Sbjct: 597 LELTVWDREPLASNDFLGGVRLGVGTGISNGE 628
>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
sapiens]
Length = 431
Score = 113 bits (282), Expect = 4e-25
Identities = 97/338 (28%), Positives = 155/338 (45%), Gaps = 47/338 (13%)
Query: 109 NLKPGSPSDLENATPKLFLEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERK 168
NL+P + S + +A P+L + E E S +S LGTL F+L + +
Sbjct: 108 NLRPAAASAVRSA-PQLQPDPEPEGDSDDSTA-------------LGTLEFTLLFEADNS 153
Query: 169 AFVVNIKEARGLPAMDEQSMTSDPYIKMTILP--EKKHKVKTRVLRKTLDPAFDETFTFY 226
A A+GL + S ++D Y+K +LP K +++T +R T P ++ET T++
Sbjct: 154 ALHCTAHRAKGLKPL--ASGSADAYVKANLLPGASKASQLRTHTVRGTRVPVWEETLTYH 211
Query: 227 GIPYTQIQ------ELALHFTIL----SFDRFSRDDIIGEVLIPLSGIELSEGKMLMNRE 276
G + +L H + R + +GE+ +PL K++ NR
Sbjct: 212 GFTRQDAECKTLRSDLGGHQAVCVRGPMVQRQWQAPSLGELRVPLR-------KLVPNRA 264
Query: 277 ------IIKRNVRKSSGR------GELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSD 324
+ KR + + G +L+SLCY S L V VL+ HL D +G SD
Sbjct: 265 RSFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSD 324
Query: 325 PYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSR 384
P+V++ L+ + SK KT V + T N FNE F + P E L ++ V D + G+
Sbjct: 325 PFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTA 384
Query: 385 NEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422
++ IG + LG+ A G HW E + ++ WH L
Sbjct: 385 DDFIGGVQLGSHASGERLRHWLECLGHSDHRLKLWHPL 422
>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
Length = 600
Score = 110 bits (276), Expect = 2e-24
Identities = 82/323 (25%), Positives = 146/323 (45%), Gaps = 35/323 (10%)
Query: 134 VSPESLKSSTSLTS------EEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187
+SPE + + S + E + K GTL + +Y+ + + +V + +P +
Sbjct: 280 LSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTG 339
Query: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247
S + + +LP KK + KT + R P F ETF F + I A+ F + R
Sbjct: 340 GNSWQ-VHLVLLPIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHR 397
Query: 248 FSRDDIIGEVLIPLSGIELSEGKMLM---------------NREIIKRNVRKSSGR---- 288
++ I+GE + L+ + L +GKM + + + + +S+
Sbjct: 398 MKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSL 456
Query: 289 -----GELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK-KRISKKK 342
E+LI L Y +TT L+ V+K H + + YVK+ L ++ + +SK K
Sbjct: 457 EHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK 516
Query: 343 THVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGG 402
T +++ PN V+ E FVF + L D+++ V + R E+IG + LG + G
Sbjct: 517 TSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEE 576
Query: 403 -EHWKEICDYPRRQIAKWHVLCD 424
HW E+ + +Q+ +WH L +
Sbjct: 577 LNHWTEMKESKGQQVCRWHALLE 599
>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
Length = 555
Score = 110 bits (276), Expect = 2e-24
Identities = 82/323 (25%), Positives = 146/323 (45%), Gaps = 35/323 (10%)
Query: 134 VSPESLKSSTSLTS------EEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187
+SPE + + S + E + K GTL + +Y+ + + +V + +P +
Sbjct: 235 LSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTG 294
Query: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247
S + + +LP KK + KT + R P F ETF F + I A+ F + R
Sbjct: 295 GNSWQ-VHLVLLPIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHR 352
Query: 248 FSRDDIIGEVLIPLSGIELSEGKMLM---------------NREIIKRNVRKSSGR---- 288
++ I+GE + L+ + L +GKM + + + + +S+
Sbjct: 353 MKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSL 411
Query: 289 -----GELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK-KRISKKK 342
E+LI L Y +TT L+ V+K H + + YVK+ L ++ + +SK K
Sbjct: 412 EHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK 471
Query: 343 THVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGG 402
T +++ PN V+ E FVF + L D+++ V + R E+IG + LG + G
Sbjct: 472 TSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEE 531
Query: 403 -EHWKEICDYPRRQIAKWHVLCD 424
HW E+ + +Q+ +WH L +
Sbjct: 532 LNHWTEMKESKGQQVCRWHALLE 554
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 110 bits (276), Expect = 2e-24
Identities = 85/324 (26%), Positives = 149/324 (45%), Gaps = 14/324 (4%)
Query: 106 PKTNLKPGSPSDLE---NATPKLFLEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLE 162
P P P+D T +LF+ + V + + + + L + L+
Sbjct: 108 PTAPASPQPPNDSRLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHYCLD 167
Query: 163 YNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKH-KVKTRVLRKTLDPAFDE 221
Y+ ++ V EA D Y++ ++ + +T + ++ L ++E
Sbjct: 168 YDCQKAELFVTRLEA----VTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQLHTTWEE 223
Query: 222 TFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRN 281
+ ++ L T+ + DRFSR + GE+ + L G + G +K +
Sbjct: 224 GLVL-PLAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGE--LKTS 280
Query: 282 VRK-SSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGL--SDPYVKVNLYHAKKRI 338
++ S+G GE+L+S+ Y N L VV++KA++L + L D VKV L H +++
Sbjct: 281 AKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARKL 340
Query: 339 SKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAE 398
KK+T K N V+NE+ +F++P + L+ SVE VL + ++ +G LG
Sbjct: 341 KKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTS 400
Query: 399 GTGGEHWKEICDYPRRQIAKWHVL 422
G+ HW+E+ PRRQIA WH L
Sbjct: 401 GSERSHWEEMLKNPRRQIAMWHQL 424
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,044,723
Number of Sequences: 37866
Number of extensions: 723799
Number of successful extensions: 2705
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 2061
Number of HSP's gapped (non-prelim): 421
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.