Guide to the Human Genome
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Search of human proteins with 242247001

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo
sapiens]
         (1583 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo ...  3159   0.0  
gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo ...  3024   0.0  
gi|4758012 clathrin heavy chain 1 [Homo sapiens]                     2610   0.0  
gi|208022639 hypothetical protein LOC130162 isoform 2 [Homo sapi...    66   2e-10
gi|208022637 hypothetical protein LOC130162 isoform 1 [Homo sapi...    66   2e-10
gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]     39   0.052
gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens]      35   0.44 
gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens]      35   0.44 
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...    33   2.2  
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...    33   2.2  
gi|154277118 spectrin repeat containing, nuclear envelope 1 isof...    32   3.7  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    32   3.7  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    32   3.7  
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ...    32   4.9  
gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo...    32   6.4  
gi|238624124 trafficking protein particle complex 9 isoform b [H...    31   8.3  
gi|238624122 trafficking protein particle complex 9 isoform a [H...    31   8.3  
gi|47078261 double C2-like domains, alpha [Homo sapiens]               31   8.3  
gi|11545839 protease, serine, 22 [Homo sapiens]                        31   8.3  

>gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo
            sapiens]
          Length = 1583

 Score = 3159 bits (8190), Expect = 0.0
 Identities = 1583/1583 (100%), Positives = 1583/1583 (100%)

Query: 1    MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA 60
            MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA
Sbjct: 1    MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA 60

Query: 61   PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA 120
            PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA
Sbjct: 61   PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA 120

Query: 121  LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA 180
            LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA
Sbjct: 121  LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA 180

Query: 181  MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN 240
            MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN
Sbjct: 181  MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN 240

Query: 241  QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA 300
            QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA
Sbjct: 241  QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA 300

Query: 301  DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA 360
            DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA
Sbjct: 301  DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA 360

Query: 361  EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI 420
            EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI
Sbjct: 361  EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI 420

Query: 421  LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL 480
            LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL
Sbjct: 421  LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL 480

Query: 481  RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE 540
            RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE
Sbjct: 481  RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE 540

Query: 541  EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL 600
            EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL
Sbjct: 541  EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL 600

Query: 601  GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV 660
            GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV
Sbjct: 601  GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV 660

Query: 661  EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN 720
            EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN
Sbjct: 661  EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN 720

Query: 721  FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR 780
            FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR
Sbjct: 721  FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR 780

Query: 781  FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF 840
            FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF
Sbjct: 781  FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF 840

Query: 841  STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY 900
            STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY
Sbjct: 841  STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY 900

Query: 901  DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL 960
            DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL
Sbjct: 901  DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL 960

Query: 961  EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020
            EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE
Sbjct: 961  EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020

Query: 1021 HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS 1080
            HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS
Sbjct: 1021 HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS 1080

Query: 1081 AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV 1140
            AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV
Sbjct: 1081 AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV 1140

Query: 1141 VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ 1200
            VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ
Sbjct: 1141 VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ 1200

Query: 1201 VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC 1260
            VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC
Sbjct: 1201 VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC 1260

Query: 1261 MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL 1320
            MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL
Sbjct: 1261 MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL 1320

Query: 1321 AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS 1380
            AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS
Sbjct: 1321 AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS 1380

Query: 1381 HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS 1440
            HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS
Sbjct: 1381 HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS 1440

Query: 1441 KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQDAMQHAAESRDAELAQKLLQWF 1500
            KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQDAMQHAAESRDAELAQKLLQWF
Sbjct: 1441 KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQDAMQHAAESRDAELAQKLLQWF 1500

Query: 1501 LEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSKVDKLDALE 1560
            LEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSKVDKLDALE
Sbjct: 1501 LEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSKVDKLDALE 1560

Query: 1561 SLRKQEEHVTEPAPLVFDFDGHE 1583
            SLRKQEEHVTEPAPLVFDFDGHE
Sbjct: 1561 SLRKQEEHVTEPAPLVFDFDGHE 1583


>gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo
            sapiens]
          Length = 1640

 Score = 3024 bits (7841), Expect = 0.0
 Identities = 1544/1643 (93%), Positives = 1558/1643 (94%), Gaps = 63/1643 (3%)

Query: 1    MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA 60
            MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA
Sbjct: 1    MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA 60

Query: 61   PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA 120
            PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA
Sbjct: 61   PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA 120

Query: 121  LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA 180
            LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA
Sbjct: 121  LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA 180

Query: 181  MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN 240
            MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN
Sbjct: 181  MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN 240

Query: 241  QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA 300
            QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA
Sbjct: 241  QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA 300

Query: 301  DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA 360
            DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA
Sbjct: 301  DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA 360

Query: 361  EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI 420
            EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI
Sbjct: 361  EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI 420

Query: 421  LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL 480
            LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL
Sbjct: 421  LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL 480

Query: 481  RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE 540
            RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE
Sbjct: 481  RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE 540

Query: 541  EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL 600
            EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL
Sbjct: 541  EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL 600

Query: 601  GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV 660
            GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV
Sbjct: 601  GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV 660

Query: 661  EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN 720
            EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN
Sbjct: 661  EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN 720

Query: 721  FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR 780
            FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR
Sbjct: 721  FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR 780

Query: 781  FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF 840
            FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF
Sbjct: 781  FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF 840

Query: 841  STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY 900
            STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY
Sbjct: 841  STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY 900

Query: 901  DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL 960
            DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL
Sbjct: 901  DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL 960

Query: 961  EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020
            EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE
Sbjct: 961  EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020

Query: 1021 HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS 1080
            HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS
Sbjct: 1021 HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS 1080

Query: 1081 AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV 1140
            AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV
Sbjct: 1081 AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV 1140

Query: 1141 VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ 1200
            VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ
Sbjct: 1141 VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ 1200

Query: 1201 VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC 1260
            VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC
Sbjct: 1201 VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC 1260

Query: 1261 MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL 1320
            MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL
Sbjct: 1261 MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL 1320

Query: 1321 AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS 1380
            AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS
Sbjct: 1321 AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS 1380

Query: 1381 HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS 1440
            HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS
Sbjct: 1381 HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS 1440

Query: 1441 KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQDAMQHAAESRD----AELAQKL 1496
            KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQ  ++ + ++ D      LAQ+L
Sbjct: 1441 KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQ-GLRASIDAYDNFDNISLAQQL 1499

Query: 1497 LQWFLEEGKRECFAACLF-------TCYDLLRPDMVLELAWRH----------------- 1532
             +  L E +  C AA L+          +L + D + + A +H                 
Sbjct: 1500 EKHQLMEFR--CIAAYLYKGNNWWAQSVELCKKDHLYKDAMQHAAESRDAELAQKLLQWF 1557

Query: 1533 --------------------------------NLVDLAMPYFIQVMREYLSKVDKLDALE 1560
                                            NLVDLAMPYFIQVMREYLSKVDKLDALE
Sbjct: 1558 LEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSKVDKLDALE 1617

Query: 1561 SLRKQEEHVTEPAPLVFDFDGHE 1583
            SLRKQEEHVTEPAPLVFDFDGHE
Sbjct: 1618 SLRKQEEHVTEPAPLVFDFDGHE 1640


>gi|4758012 clathrin heavy chain 1 [Homo sapiens]
          Length = 1675

 Score = 2610 bits (6766), Expect = 0.0
 Identities = 1309/1637 (79%), Positives = 1454/1637 (88%), Gaps = 63/1637 (3%)

Query: 1    MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA 60
            MAQILP+RFQEH QLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQV IIDM+DP  
Sbjct: 1    MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSN 60

Query: 61   PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA 120
            PIRRPISA+SAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTM ++V FWKW+S+NTVA
Sbjct: 61   PIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVA 120

Query: 121  LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA 180
            LVT+ AVYHWSMEG+SQP+KMFDRH+SL GCQ+I+YRTD  QKWLLL GISAQQNRVVGA
Sbjct: 121  LVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGA 180

Query: 181  MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN 240
            MQLYSVDRKVSQPIEGHAA+FA+FKMEGNA+ +TLFCFAVR   GGKLHIIEVG P  GN
Sbjct: 181  MQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGN 240

Query: 241  QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA 300
            QPF KKAVDVFFPPEAQNDFPVAMQI  KH V++LITKYGY+HLYDLE+G CI MNRIS 
Sbjct: 241  QPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISG 300

Query: 301  DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA 360
            +TIFVTAPH+ T+GIIGVN+KGQVLSVCVEE+NI+ Y TNVLQNPDL LR+AVR+NLAGA
Sbjct: 301  ETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGA 360

Query: 361  EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI 420
            E+LF RKFN LFAQG+Y+EAAKVAA+APKGILRT +T+++FQS+PAQ GQ SPLLQYFGI
Sbjct: 361  EELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGI 420

Query: 421  LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL 480
            LLDQGQLNK ESLELC  VLQQGRKQLLEKWLKEDKLECSEELGDLVK+ DP LALSVYL
Sbjct: 421  LLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYL 480

Query: 481  RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE 540
            RANVP+KVIQCFAETGQ QKIVLYAKKVGYTPDWIFLLR VM+ISP+QG QF++MLVQDE
Sbjct: 481  RANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDE 540

Query: 541  EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL 600
            EPLA+I+QIVD+FME +LIQQCT+FLLDALKNNRP+EG LQT LLEMNL+HAPQVADAIL
Sbjct: 541  EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAIL 600

Query: 601  GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV 660
            GN+MFTHYDRAHIAQLCEKAGLLQ+ALEH+TDLYDIKRAVVHTHLLNPEWLVN+FGSLSV
Sbjct: 601  GNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSV 660

Query: 661  EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN 720
            EDS+ECL AMLSANIRQNLQ+CVQVASKYHEQL TQ+L+ELFESFKS++GLFYFLGSIVN
Sbjct: 661  EDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVN 720

Query: 721  FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR 780
            FSQDPDVH KYIQAACKTGQIKEVERICRES+CY+PERVKNFLKEAKLTDQLPLIIVCDR
Sbjct: 721  FSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDR 780

Query: 781  FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF 840
            F FVHDLVLYLYRNNLQ+YIEIYVQKVNPSR P VIGGLLDVDCSE+VIK+LI+ VRGQF
Sbjct: 781  FDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQF 840

Query: 841  STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY 900
            STDELVAEVEKRNRLKLLLPWLE++I EGCEEPATHNALAKIYIDSNN+PE FLREN YY
Sbjct: 841  STDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYY 900

Query: 901  DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL 960
            DS VVG+YCEKRDPHLACVAYERGQCDLELI VCNENSLFKS +RYLV RKDPELW  VL
Sbjct: 901  DSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVL 960

Query: 961  EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020
             E+NP RR LIDQVVQTALSET+DPEE+SVTVKAFMTADLPNELIELLEKIVLDNSVFSE
Sbjct: 961  LESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020

Query: 1021 HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS 1080
            HRNLQNLLILTAIKADRTRVMEYI+RLDNYDA DIA+IA+S+ L+EEAF +F KFD+N S
Sbjct: 1021 HRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTS 1080

Query: 1081 AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV 1140
            A+QVLIEHIGNLDRAYEFAERCNEPAVWSQLA+AQLQK +VKEAI+SYI+ DDPSSY+EV
Sbjct: 1081 AVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEV 1140

Query: 1141 VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ 1200
            VQ+A+ S NWE+LVK+LQMARKK RESY+ETELIFALAKT+R++ELE+FINGPNNAHIQQ
Sbjct: 1141 VQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQ 1200

Query: 1201 VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC 1260
            VGDRCY+E MY+AAKLLY+NVSNF RLASTLVHLGEYQAAVD +RKA+STRTWKEVCFAC
Sbjct: 1201 VGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFAC 1260

Query: 1261 MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL 1320
            +DG+EFR AQ+CGLHIV+HADELEEL+ YYQDRGYFEELI +LEAALGLERAHMGMFTEL
Sbjct: 1261 VDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTEL 1320

Query: 1321 AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS 1380
            AILYSKFKPQKM EHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNA++TMM+
Sbjct: 1321 AILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMN 1380

Query: 1381 HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS 1440
            HPT+AWKEGQFKDIITKVANVEL YRA+QFYL++KPLL+NDLL+VLSPRLDHT  V++FS
Sbjct: 1381 HPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFS 1440

Query: 1441 KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQDAMQHAAESRD----AELAQKL 1496
            K  QLPLVKPYLRSVQ+HNNKSVNE+LN+L   EEDYQ A++ + ++ D      LAQ+L
Sbjct: 1441 KVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQ-ALRTSIDAYDNFDNISLAQRL 1499

Query: 1497 LQWFLEEGKRECFAACLF-------TCYDLLRPDMVLELAWRH-------NLVDLAMPYF 1542
             +  L E +R   AA LF          +L + D + + A ++        L +  + +F
Sbjct: 1500 EKHELIEFRR--IAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWF 1557

Query: 1543 IQ------------------------------------------VMREYLSKVDKLDALE 1560
            +Q                                          VM+EYL+KVDKLDA E
Sbjct: 1558 LQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASE 1617

Query: 1561 SLRKQEEHVTEPAPLVF 1577
            SLRK+EE  TE  P+V+
Sbjct: 1618 SLRKEEEQATETQPIVY 1634


>gi|208022639 hypothetical protein LOC130162 isoform 2 [Homo
           sapiens]
          Length = 464

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 15/160 (9%)

Query: 364 FVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGILLD 423
           ++ +FN L + G Y +AA  AA++P+ ILR   T+  F+++    G+  PLL +F  L  
Sbjct: 175 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFI 234

Query: 424 QGQ-----LNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLV----------K 468
                   ++   +LE     L + R  L+  W+ +++L  SEE GD++          K
Sbjct: 235 TSHAFPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNK 294

Query: 469 TTDPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYAKKV 508
                LA  VY    +  K I C  + GQ  +++ Y +++
Sbjct: 295 AKCLALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQL 334


>gi|208022637 hypothetical protein LOC130162 isoform 1 [Homo
           sapiens]
          Length = 586

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 15/160 (9%)

Query: 364 FVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGILLD 423
           ++ +FN L + G Y +AA  AA++P+ ILR   T+  F+++    G+  PLL +F  L  
Sbjct: 297 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFI 356

Query: 424 QGQ-----LNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLV----------K 468
                   ++   +LE     L + R  L+  W+ +++L  SEE GD++          K
Sbjct: 357 TSHAFPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNK 416

Query: 469 TTDPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYAKKV 508
                LA  VY    +  K I C  + GQ  +++ Y +++
Sbjct: 417 AKCLALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQL 456


>gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]
          Length = 845

 Score = 38.5 bits (88), Expect = 0.052
 Identities = 56/245 (22%), Positives = 87/245 (35%), Gaps = 42/245 (17%)

Query: 498 FQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDEEPLANISQIVDIFMENS 557
           F K++     + +TP  I   RG+M    E+        V DE+  + +S  +D  +E  
Sbjct: 105 FGKVIYTLSALSWTP--IAQNRGIMPFPTEEES------VGDEDIYSGLSDQIDDTVEED 156

Query: 558 LIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAILGNKMFTHYDRAHIAQLC 617
                   L D ++N       +   L+    V  P            T YD+      C
Sbjct: 157 ------EDLYDCVENEEAEGDEIYEDLMRSEPVSMPP---------KMTEYDKR-----C 196

Query: 618 EKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSVEDSVECLHAMLSANIRQ 677
                +QQ  E YTD        +  H L P  L  F     +E        ++  NI  
Sbjct: 197 CCLREIQQTEEKYTDTL----GSIQQHFLKP--LQRFLKPQDIE--------IIFINIED 242

Query: 678 NLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVNFSQDPDVHLKYIQAACK 737
            L++      +  E LGT     L++ F  YK  F   G   +  +    HL  + AA +
Sbjct: 243 LLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFLVYGRYCSQVESASKHLDRVAAARE 302

Query: 738 TGQIK 742
             Q+K
Sbjct: 303 DVQMK 307


>gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens]
          Length = 829

 Score = 35.4 bits (80), Expect = 0.44
 Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 1066 EEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQK-DLVKEA 1124
            EE   +  +   + SA+++++E + ++D+A EFA+  ++  +W  L    + K   +   
Sbjct: 629  EETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGL 688

Query: 1125 INSYIRGDDPSSYLEVVQSASRSNNWED-LVKFLQ 1158
            +N+     DP   +  ++      N  D LVK LQ
Sbjct: 689  LNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQ 723


>gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens]
          Length = 854

 Score = 35.4 bits (80), Expect = 0.44
 Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 1066 EEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQK-DLVKEA 1124
            EE   +  +   + SA+++++E + ++D+A EFA+  ++  +W  L    + K   +   
Sbjct: 654  EETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGL 713

Query: 1125 INSYIRGDDPSSYLEVVQSASRSNNWED-LVKFLQ 1158
            +N+     DP   +  ++      N  D LVK LQ
Sbjct: 714  LNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQ 748


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
            [Homo sapiens]
          Length = 357

 Score = 33.1 bits (74), Expect = 2.2
 Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 8/84 (9%)

Query: 1136 SYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETEL-IFALAKTSRVSELEDFINGPN 1194
            ++ EVV +  ++      VK +     KG+ES IE E+ +    K   +  LED    PN
Sbjct: 33   AFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPN 92

Query: 1195 NAHI-------QQVGDRCYEEGMY 1211
            + ++        ++ DR  E+G Y
Sbjct: 93   HLYLVMQLVSGGELFDRIVEKGFY 116


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2
            [Homo sapiens]
          Length = 385

 Score = 33.1 bits (74), Expect = 2.2
 Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 8/84 (9%)

Query: 1136 SYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETEL-IFALAKTSRVSELEDFINGPN 1194
            ++ EVV +  ++      VK +     KG+ES IE E+ +    K   +  LED    PN
Sbjct: 33   AFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPN 92

Query: 1195 NAHI-------QQVGDRCYEEGMY 1211
            + ++        ++ DR  E+G Y
Sbjct: 93   HLYLVMQLVSGGELFDRIVEKGFY 116


>gi|154277118 spectrin repeat containing, nuclear envelope 1 isoform 4
            [Homo sapiens]
          Length = 3321

 Score = 32.3 bits (72), Expect = 3.7
 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 8/132 (6%)

Query: 1117 QKDLVKEAINSYIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFA 1176
            Q  L+K+ +++YI  DD S   E V+   R   WE+L   L + R++  E   E  +   
Sbjct: 2254 QLSLLKDTLSAYISADDISILNERVELLQR--QWEELCHQLSLRRQQIGERLNEWAVF-- 2309

Query: 1177 LAKTSRVSELEDFINGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGE 1236
               + +  EL +++     + + Q GD   EE + +  K     ++        L  +GE
Sbjct: 2310 ---SEKNKELCEWLT-QMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGE 2365

Query: 1237 YQAAVDNSRKAS 1248
              A   +  KAS
Sbjct: 2366 RLAKASHESKAS 2377


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 32.3 bits (72), Expect = 3.7
 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 8/132 (6%)

Query: 1117 QKDLVKEAINSYIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFA 1176
            Q  L+K+ +++YI  DD S   E V+   R   WE+L   L + R++  E   E  +   
Sbjct: 7659 QLSLLKDTLSAYISADDISILNERVELLQR--QWEELCHQLSLRRQQIGERLNEWAVF-- 7714

Query: 1177 LAKTSRVSELEDFINGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGE 1236
               + +  EL +++     + + Q GD   EE + +  K     ++        L  +GE
Sbjct: 7715 ---SEKNKELCEWLT-QMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGE 7770

Query: 1237 YQAAVDNSRKAS 1248
              A   +  KAS
Sbjct: 7771 RLAKASHESKAS 7782


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 32.3 bits (72), Expect = 3.7
 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 8/132 (6%)

Query: 1117 QKDLVKEAINSYIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFA 1176
            Q  L+K+ +++YI  DD S   E V+   R   WE+L   L + R++  E   E  +   
Sbjct: 7730 QLSLLKDTLSAYISADDISILNERVELLQR--QWEELCHQLSLRRQQIGERLNEWAVF-- 7785

Query: 1177 LAKTSRVSELEDFINGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGE 1236
               + +  EL +++     + + Q GD   EE + +  K     ++        L  +GE
Sbjct: 7786 ---SEKNKELCEWLT-QMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGE 7841

Query: 1237 YQAAVDNSRKAS 1248
              A   +  KAS
Sbjct: 7842 RLAKASHESKAS 7853


>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
            sapiens]
          Length = 1386

 Score = 32.0 bits (71), Expect = 4.9
 Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 1093 DRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEVVQSASRSNN 1149
            D+A  FAE  +EP V+S +   + + ++VK   N++ +  DP      V S +R NN
Sbjct: 395  DKALTFAET-SEPVVYSLITLLEEESEIVKLLTNTHHKYSDPPVNFLPVPSRTRINN 450


>gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo
           sapiens]
          Length = 859

 Score = 31.6 bits (70), Expect = 6.4
 Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 4/94 (4%)

Query: 179 GAMQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATL--FCFAVRNPTGGKLHII-EVGQ 235
           G   +Y+  ++V   + G A    + K      P TL   C  +    GG  +I+   G+
Sbjct: 524 GKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGR 583

Query: 236 PAAGNQPFVKKAVDVFFPPEAQNDFP-VAMQIGA 268
           P    QP +    DV  PP      P +A  +G+
Sbjct: 584 PPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGS 617


>gi|238624124 trafficking protein particle complex 9 isoform b [Homo
           sapiens]
          Length = 1148

 Score = 31.2 bits (69), Expect = 8.3
 Identities = 13/31 (41%), Positives = 20/31 (64%)

Query: 610 RAHIAQLCEKAGLLQQALEHYTDLYDIKRAV 640
           R H+  LC +AG+LQ +L HY    ++ R+V
Sbjct: 206 RKHVGDLCLQAGMLQDSLVHYHMSVELLRSV 236


>gi|238624122 trafficking protein particle complex 9 isoform a [Homo
           sapiens]
          Length = 1246

 Score = 31.2 bits (69), Expect = 8.3
 Identities = 13/31 (41%), Positives = 20/31 (64%)

Query: 610 RAHIAQLCEKAGLLQQALEHYTDLYDIKRAV 640
           R H+  LC +AG+LQ +L HY    ++ R+V
Sbjct: 304 RKHVGDLCLQAGMLQDSLVHYHMSVELLRSV 334


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score = 31.2 bits (69), Expect = 8.3
 Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 18/146 (12%)

Query: 724 DPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDRFGF 783
           DP V L  +  ACK  ++K   +    +  +N +   + + +  +T ++  I VCD    
Sbjct: 126 DPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKL 185

Query: 784 VHDLVLYLYRNNLQR-------YIEIYVQKVNPSRTPAVIGGLL-DVDCSEEVIKHLIMA 835
            H+  +   R  L+R       +  I +++  P  +P+ +   L  + C    +K L  A
Sbjct: 186 SHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISC---YLKELEQA 242

Query: 836 VRGQFSTDELVAEVEKRNRLKLLLPW 861
            +GQ         +E+R R+ L L +
Sbjct: 243 EQGQ-------GLLEERGRILLSLSY 261


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score = 31.2 bits (69), Expect = 8.3
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 6/70 (8%)

Query: 1381 HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS 1440
            HP  +WKEG   DI    A V L  R++QF     P+ + D  + L P   H W   + S
Sbjct: 129  HPVYSWKEGACADI----ALVRL-ERSIQFSERVLPICLPDASIHLPPN-THCWISGWGS 182

Query: 1441 KAGQLPLVKP 1450
                +PL  P
Sbjct: 183  IQDGVPLPHP 192


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,776,138
Number of Sequences: 37866
Number of extensions: 2377856
Number of successful extensions: 5523
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 5487
Number of HSP's gapped (non-prelim): 35
length of query: 1583
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1467
effective length of database: 13,855,062
effective search space: 20325375954
effective search space used: 20325375954
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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