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Search of human proteins with 239985422
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239985422 pyruvate dehyrogenase phosphatase catalytic
subunit 1 isoform 2 [Homo sapiens]
(562 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit... 1155 0.0
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit... 1155 0.0
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit... 1155 0.0
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ... 1103 0.0
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit... 1103 0.0
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo... 505 e-143
gi|13540531 integrin-linked kinase-associated protein phosphatas... 63 6e-10
gi|4505997 protein phosphatase 1D [Homo sapiens] 60 5e-09
gi|4505999 protein phosphatase 1G [Homo sapiens] 60 7e-09
gi|29826282 protein phosphatase 1G [Homo sapiens] 60 7e-09
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] 56 1e-07
gi|122937199 protein phosphatase 1B-like [Homo sapiens] 55 2e-07
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens] 50 7e-06
gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens] 50 7e-06
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens] 50 7e-06
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens] 50 7e-06
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho... 50 7e-06
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho... 45 2e-04
gi|7661862 protein phosphatase 1F [Homo sapiens] 45 2e-04
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens] 44 3e-04
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] 44 4e-04
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] 44 4e-04
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] 44 4e-04
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens] 44 5e-04
gi|5174703 mitogen-activated protein kinase kinase kinase 7 inte... 40 0.004
gi|41281798 mitogen-activated protein kinase kinase kinase 7 int... 40 0.004
gi|30089948 protein phosphatase 1E [Homo sapiens] 40 0.006
gi|65301141 PH domain and leucine rich repeat protein phosphatas... 36 0.11
gi|37221175 PH domain and leucine rich repeat protein phosphatas... 34 0.41
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom... 33 0.53
>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 1155 bits (2988), Expect = 0.0
Identities = 562/562 (100%), Positives = 562/562 (100%)
Query: 1 MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCS 60
MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCS
Sbjct: 1 MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCS 60
Query: 61 SSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS 120
SSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS
Sbjct: 61 SSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS 120
Query: 121 FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAV 180
FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAV
Sbjct: 121 FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAV 180
Query: 181 SERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTY 240
SERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTY
Sbjct: 181 SERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTY 240
Query: 241 WQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATAC 300
WQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATAC
Sbjct: 241 WQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATAC 300
Query: 301 VAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAK 360
VAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAK
Sbjct: 301 VAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAK 360
Query: 361 SVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYL 420
SVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYL
Sbjct: 361 SVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYL 420
Query: 421 TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTL 480
TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTL
Sbjct: 421 TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTL 480
Query: 481 GQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYR 540
GQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYR
Sbjct: 481 GQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYR 540
Query: 541 DDITIIVVQFNSHVVGAYQNQE 562
DDITIIVVQFNSHVVGAYQNQE
Sbjct: 541 DDITIIVVQFNSHVVGAYQNQE 562
>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 1155 bits (2988), Expect = 0.0
Identities = 562/562 (100%), Positives = 562/562 (100%)
Query: 1 MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCS 60
MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCS
Sbjct: 1 MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCS 60
Query: 61 SSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS 120
SSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS
Sbjct: 61 SSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS 120
Query: 121 FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAV 180
FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAV
Sbjct: 121 FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAV 180
Query: 181 SERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTY 240
SERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTY
Sbjct: 181 SERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTY 240
Query: 241 WQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATAC 300
WQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATAC
Sbjct: 241 WQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATAC 300
Query: 301 VAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAK 360
VAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAK
Sbjct: 301 VAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAK 360
Query: 361 SVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYL 420
SVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYL
Sbjct: 361 SVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYL 420
Query: 421 TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTL 480
TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTL
Sbjct: 421 TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTL 480
Query: 481 GQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYR 540
GQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYR
Sbjct: 481 GQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYR 540
Query: 541 DDITIIVVQFNSHVVGAYQNQE 562
DDITIIVVQFNSHVVGAYQNQE
Sbjct: 541 DDITIIVVQFNSHVVGAYQNQE 562
>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 1 [Homo sapiens]
Length = 596
Score = 1155 bits (2988), Expect = 0.0
Identities = 562/562 (100%), Positives = 562/562 (100%)
Query: 1 MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCS 60
MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCS
Sbjct: 35 MCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCS 94
Query: 61 SSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS 120
SSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS
Sbjct: 95 SSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYS 154
Query: 121 FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAV 180
FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAV
Sbjct: 155 FKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAV 214
Query: 181 SERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTY 240
SERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTY
Sbjct: 215 SERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTY 274
Query: 241 WQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATAC 300
WQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATAC
Sbjct: 275 WQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATAC 334
Query: 301 VAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAK 360
VAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAK
Sbjct: 335 VAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAK 394
Query: 361 SVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYL 420
SVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYL
Sbjct: 395 SVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYL 454
Query: 421 TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTL 480
TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTL
Sbjct: 455 TAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTL 514
Query: 481 GQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYR 540
GQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYR
Sbjct: 515 GQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYR 574
Query: 541 DDITIIVVQFNSHVVGAYQNQE 562
DDITIIVVQFNSHVVGAYQNQE
Sbjct: 575 DDITIIVVQFNSHVVGAYQNQE 596
>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 1103 bits (2854), Expect = 0.0
Identities = 537/537 (100%), Positives = 537/537 (100%)
Query: 26 MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKE 85
MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKE
Sbjct: 1 MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKE 60
Query: 86 NWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPAN 145
NWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPAN
Sbjct: 61 NWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPAN 120
Query: 146 APIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAV 205
APIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAV
Sbjct: 121 APIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAV 180
Query: 206 ESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAF 265
ESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAF
Sbjct: 181 ESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAF 240
Query: 266 KRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQE 325
KRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQE
Sbjct: 241 KRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQE 300
Query: 326 EDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKW 385
EDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKW
Sbjct: 301 EDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKW 360
Query: 386 SIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGL 445
SIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGL
Sbjct: 361 SIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGL 420
Query: 446 WETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAAT 505
WETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAAT
Sbjct: 421 WETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAAT 480
Query: 506 HLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE 562
HLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE
Sbjct: 481 HLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE 537
>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 1103 bits (2854), Expect = 0.0
Identities = 537/537 (100%), Positives = 537/537 (100%)
Query: 26 MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKE 85
MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKE
Sbjct: 1 MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKE 60
Query: 86 NWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPAN 145
NWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPAN
Sbjct: 61 NWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPAN 120
Query: 146 APIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAV 205
APIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAV
Sbjct: 121 APIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAV 180
Query: 206 ESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAF 265
ESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAF
Sbjct: 181 ESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAF 240
Query: 266 KRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQE 325
KRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQE
Sbjct: 241 KRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQE 300
Query: 326 EDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKW 385
EDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKW
Sbjct: 301 EDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKW 360
Query: 386 SIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGL 445
SIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGL
Sbjct: 361 SIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGL 420
Query: 446 WETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAAT 505
WETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAAT
Sbjct: 421 WETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAAT 480
Query: 506 HLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE 562
HLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE
Sbjct: 481 HLIRHAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE 537
>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
sapiens]
Length = 529
Score = 505 bits (1300), Expect = e-143
Identities = 257/469 (54%), Positives = 344/469 (73%), Gaps = 12/469 (2%)
Query: 95 RYASTPQKFY---LTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDR 151
R+ ST + + L+P Q+N +L+A E + K+ + + + +S+L F+SNQL AN+P+EDR
Sbjct: 64 RHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDR 123
Query: 152 RSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRAL 211
R A+CLQT G++ G+FDGH G AC+QAVSERLFYY+AVSL+ H+TL +E A+ES + L
Sbjct: 124 RGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPL 183
Query: 212 LPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDND 271
LPIL W KHP D K+ + ++ + LR YWQEL+DL+ + ++EAL+ +F+RLD+D
Sbjct: 184 LPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHM--EMGLSIEEALMYSFQRLDSD 241
Query: 272 ISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWS 331
ISLE Q + L L+VAFSGATAC+AHVDG+ LHVAN GD RA+LGVQE++G WS
Sbjct: 242 ISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWS 301
Query: 332 AVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQK 391
+ L+ DHNA N+ EL RLK EHP+SE ++++ +DRLLG+L+P RAFGDV+ KWS +LQ+
Sbjct: 302 CLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQR 361
Query: 392 RVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHR 451
++E G + N Y +F PP+Y+TPPYLTAEPEVTYHRLRPQDKFLVLA+DGLW+ +
Sbjct: 362 SILERGFNTEALNIY-QFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN 420
Query: 452 QDVVR-IVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFE-DQNAATHLIR 509
+DVVR +VG H+ +A LG M LL +R K S + E DQNAAT LIR
Sbjct: 421 EDVVRLVVGHLAEADWHKTDLA--QRPANLGLMQSLLLQR--KASGLHEADQNAATRLIR 476
Query: 510 HAVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAY 558
HA+GNNE+G ++ ERL+ ML+LPE+LARMYRDDIT+ VV FNS +GAY
Sbjct: 477 HAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAY 525
>gi|13540531 integrin-linked kinase-associated protein phosphatase
2C [Homo sapiens]
Length = 392
Score = 63.2 bits (152), Expect = 6e-10
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 51/209 (24%)
Query: 252 STDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATA-CVAHVDGVDLH 310
S + VK L++ FK D + +A P G+TA CV VD + L+
Sbjct: 182 SVEKTVKRCLLDTFKHTDEEFLKQASSQKP----------AWKDGSTATCVLAVDNI-LY 230
Query: 311 VANTGDSRAML-GVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLL 369
+AN GDSRA+L EE +A++LS +HN E R++ +A V+ R+L
Sbjct: 231 IANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQ------KAGGNVRDGRVL 284
Query: 370 GLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYH 429
G+L R+ GD ++K G +T+ P++
Sbjct: 285 GVLEVSRSIGDGQYK----------RCG----------------------VTSVPDIRRC 312
Query: 430 RLRPQDKFLVLATDGLWETMHRQDVVRIV 458
+L P D+F++LA DGL++ ++ V +
Sbjct: 313 QLTPNDRFILLACDGLFKVFTPEEAVNFI 341
>gi|4505997 protein phosphatase 1D [Homo sapiens]
Length = 605
Score = 60.1 bits (144), Expect = 5e-09
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 56/202 (27%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEE--DGSWSAVTLSNDHNAQNERELERLK- 351
SG TA V + G+ ++VA+ GDS +LG+Q++ D AV ++ DH + +E ER++
Sbjct: 171 SGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEG 230
Query: 352 ---------------LEHPKSEAKSVVKQDRLLGLLMPF----RAFGDVKFKWSIDLQKR 392
+ P+ V++ ++ + PF RA GD+ WS D
Sbjct: 231 LGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI-PFLAVARALGDL---WSYD---- 282
Query: 393 VIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQD-KFLVLATDGLWETMHR 451
F + P EP+ + H L PQ K+++L +DGLW +
Sbjct: 283 ----------------FFSGEFVVSP----EPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322
Query: 452 QDVVRIVGE-----YLTGMHHQ 468
QD + + + YL G H Q
Sbjct: 323 QDAISMCQDQEEKKYLMGEHGQ 344
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 59.7 bits (143), Expect = 7e-09
Identities = 51/164 (31%), Positives = 74/164 (45%), Gaps = 34/164 (20%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
SG TA VA + G L VAN GDSR ++ E G A+ +S DH ++E EL R+K
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVVS---EAGK--ALDMSYDHKPEDEVELARIK--- 378
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
+ V R+ G L RA GD +K + K +PP
Sbjct: 379 --NAGGKVTMDGRVNGGLNLSRAIGDHFYKRN---------------------KNLPPEE 415
Query: 415 HTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 458
++A P++ L +F+V+A DG+W M Q+VV +
Sbjct: 416 QM---ISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFI 456
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 59.7 bits (143), Expect = 7e-09
Identities = 51/164 (31%), Positives = 74/164 (45%), Gaps = 34/164 (20%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
SG TA VA + G L VAN GDSR ++ E G A+ +S DH ++E EL R+K
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVVS---EAGK--ALDMSYDHKPEDEVELARIK--- 378
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
+ V R+ G L RA GD +K + K +PP
Sbjct: 379 --NAGGKVTMDGRVNGGLNLSRAIGDHFYKRN---------------------KNLPPEE 415
Query: 415 HTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 458
++A P++ L +F+V+A DG+W M Q+VV +
Sbjct: 416 QM---ISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFI 456
>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
Length = 360
Score = 55.8 bits (133), Expect = 1e-07
Identities = 63/240 (26%), Positives = 97/240 (40%), Gaps = 57/240 (23%)
Query: 244 LIDLNTGESTDIDVKEALINAFKR-------------LDNDISLEAQV-GDPNSFLNYLV 289
+ D + GE+ VK L A K+ L LE Q+ L L
Sbjct: 126 IFDGHGGETAAEYVKSRLPEALKQHLQDYEKDKENSVLSYQTILEQQILSIDREMLEKLT 185
Query: 290 LRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELER 349
+ +G T +A + DL VAN GDSR +L ++DG +A+ LS+DH +E +R
Sbjct: 186 VSYDEAGTTCLIALLSDKDLTVANVGDSRGVL--CDKDG--NAIPLSHDHKPYQLKERKR 241
Query: 350 LKLEHPKSEAKSVVKQD---RLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEY 406
+K A + + R+ G+L R+ GD K V+ PD L
Sbjct: 242 IK------RAGGFISFNGSWRVQGILAMSRSLGDYPLK-----NLNVVIPDPDIL----- 285
Query: 407 TKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMH 466
T+ + Q +F++LA+DGLW+ ++ VR + E L H
Sbjct: 286 --------------------TFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPH 325
Score = 30.0 bits (66), Expect = 5.9
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
Query: 148 IEDRRSAATCL--QTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAV 205
+EDR T L +T + G+FDGH G ++ V RL + L +E + EN+V
Sbjct: 105 MEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYEK--DKENSV 162
Query: 206 ESGRALL 212
S + +L
Sbjct: 163 LSYQTIL 169
>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
Length = 430
Score = 54.7 bits (130), Expect = 2e-07
Identities = 63/220 (28%), Positives = 89/220 (40%), Gaps = 50/220 (22%)
Query: 244 LIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAH 303
L +L S V+EAL AF D L L RV G TA V
Sbjct: 123 LQELGPEPSEPEGVREALRRAFLSADER-------------LRSLWPRVETGGCTAVVLL 169
Query: 304 VDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSN-DHNAQNERELERLKLEHPKSEAKSV 362
V L++A+ GDSRA+L AV S DH RE ER+ A
Sbjct: 170 VSPRFLYLAHCGDSRAVLSRA------GAVAFSTEDHRPLRPRERERIHA------AGGT 217
Query: 363 VKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTA 422
+++ R+ G L RA GD +K P + PP ++A
Sbjct: 218 IRRRRVEGSLAVSRALGDFTYK-----------EAPGR----------PPELQL---VSA 253
Query: 423 EPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYL 462
EPEV + +D+F++LA+DG+W+T+ + +V L
Sbjct: 254 EPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRL 293
>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
Length = 380
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
SG+TA + ++ N GDSRA+L +G T DH N RE ER++
Sbjct: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
A V R+ G L RA GD +K V GP
Sbjct: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
Query: 415 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 458
T ++ EPEV Y LR + D+F++LA DG+W+ M +++ V
Sbjct: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
Length = 327
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
SG+TA + ++ N GDSRA+L +G T DH N RE ER++
Sbjct: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
A V R+ G L RA GD +K V GP
Sbjct: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
Query: 415 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 458
T ++ EPEV Y LR + D+F++LA DG+W+ M +++ V
Sbjct: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
Length = 387
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
SG+TA + ++ N GDSRA+L +G T DH N RE ER++
Sbjct: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
A V R+ G L RA GD +K V GP
Sbjct: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
Query: 415 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 458
T ++ EPEV Y LR + D+F++LA DG+W+ M +++ V
Sbjct: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
Length = 479
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
SG+TA + ++ N GDSRA+L +G T DH N RE ER++
Sbjct: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
A V R+ G L RA GD +K V GP
Sbjct: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
Query: 415 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 458
T ++ EPEV Y LR + D+F++LA DG+W+ M +++ V
Sbjct: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
sapiens]
Length = 514
Score = 49.7 bits (117), Expect = 7e-06
Identities = 81/340 (23%), Positives = 135/340 (39%), Gaps = 60/340 (17%)
Query: 167 VFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFS 226
+FDGHAG + S L ++I E L +I + +++ A+LP + P + +
Sbjct: 149 LFDGHAGSGAAVVASRLLQHHIT------EQLQDIVDILKNS-AVLPPTCLGEEPENTPA 201
Query: 227 KEASKLYFNSLRTYWQELIDLNTGESTDIDVKE---------ALINAFKRLDNDISLEAQ 277
+ SLR +T + K+ AL +AFK +D I E
Sbjct: 202 NSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERS 261
Query: 278 VGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSN 337
+Y + G TA + L+VAN GDSRA++ E + +S+
Sbjct: 262 --------SYNIS----GGCTALIVICLLGKLYVANAGDSRAIIIRNGE-----IIPMSS 304
Query: 338 DHNAQNERE-LERLKLEHPKSEAKSVVK-------QDRLLGLLMPFRAFG---------- 379
+ + ER+ L+ L P Q + LG M +R F
Sbjct: 305 EFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIE 364
Query: 380 --DVKFK--WSIDLQKRVIES-GPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP- 433
D+KF + + RV+ + G + + K N + P+L++ PEV + L
Sbjct: 365 DEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKY 424
Query: 434 ---QDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQP 470
D L+LATDGLW+ + ++V + ++L P
Sbjct: 425 DHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDP 464
>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
sapiens]
Length = 372
Score = 44.7 bits (104), Expect = 2e-04
Identities = 55/207 (26%), Positives = 88/207 (42%), Gaps = 48/207 (23%)
Query: 256 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHV-DGVDLHVANT 314
+++ L AF +D S A++ + L SG TA VA + DG++L VA+
Sbjct: 155 NLETLLTLAFLEIDKAFSSHARLSADATLLT--------SGTTATVALLRDGIELVVASV 206
Query: 315 GDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMP 374
GDSRA+L + + + L+ DH + + E ER+K + A + + Q + G L
Sbjct: 207 GDSRAILCRKGK-----PMKLTIDHTPERKDEKERIK-KCGGFVAWNSLGQPHVNGRLAM 260
Query: 375 FRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRL-RP 433
R+ GD+ K S + AEPE +L
Sbjct: 261 TRSIGDLDLKTS--------------------------------GVIAEPETKRIKLHHA 288
Query: 434 QDKFLVLATDGLWETMHRQDVVRIVGE 460
D FLVL TDG+ ++ Q++ V +
Sbjct: 289 DDSFLVLTTDGINFMVNSQEICDFVNQ 315
>gi|7661862 protein phosphatase 1F [Homo sapiens]
Length = 454
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/210 (25%), Positives = 78/210 (37%), Gaps = 57/210 (27%)
Query: 256 DVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTG 315
D + AL AF+R D FL SG T A + G LHVA G
Sbjct: 226 DPEGALREAFRRTDQ------------MFLRKAKRERLQSGTTGVCALIAGATLHVAWLG 273
Query: 316 DSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQD--RLLGLLM 373
DS+ +L Q + V L H + + E R++ + V D R+ G L
Sbjct: 274 DSQVILVQQGQ-----VVKLMEPHRPERQDEKARIE-----ALGGFVSHMDCWRVNGTLA 323
Query: 374 PFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP 433
RA GDV K PY++ E + L
Sbjct: 324 VSRAIGDVFQK---------------------------------PYVSGEADAASRALTG 350
Query: 434 QDKFLVLATDGLWETMHRQDVVRIVGEYLT 463
+ +L+LA DG ++ + Q+VV +V +LT
Sbjct: 351 SEDYLLLACDGFFDVVPHQEVVGLVQSHLT 380
>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
Length = 298
Score = 44.3 bits (103), Expect = 3e-04
Identities = 62/239 (25%), Positives = 98/239 (41%), Gaps = 58/239 (24%)
Query: 260 ALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRA 319
AL +AF+ D I E + G TA VA L++AN GDSRA
Sbjct: 30 ALESAFQECDEVIGRELEASGQ------------MGGCTALVAVSLQGKLYMANAGDSRA 77
Query: 320 MLGVQEEDGSWSAVTLSNDHNAQNERE-LERLKLEHPKSEAKSVVKQDRLLGLLMPFRAF 378
+L ++E LS + + ER+ +++L +P+ A + L P R
Sbjct: 78 ILVRRDE-----IRPLSFEFTPETERQRIQQLAFVYPELLAGEFTR------LEFPRRLK 126
Query: 379 GD-----VKFK------WSI------DLQKRVIESGPDQ------------LNDNEYTKF 409
GD V F+ WS DL+ +I Q L D++ +
Sbjct: 127 GDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQL-RV 185
Query: 410 IPPNYHTPPYLTAEPEVTYHRLRP----QDKFLVLATDGLWETMHRQDVVRIVGEYLTG 464
+ N P+L + P+VT + +D +V+ATDGLW+ + + V +V +L G
Sbjct: 186 LDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPG 244
>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
Length = 382
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 36/165 (21%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
SG+TA + + N GDSR +L + + DH N E ER++
Sbjct: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRK-----VHFFTQDHKPSNPLEKERIQ--- 176
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
A V R+ G L RA GD +K V GP
Sbjct: 177 ---NAGGSVMIQRVNGSLAVSRALGDFDYKC-------VHGKGP---------------- 210
Query: 415 HTPPYLTAEPEV-TYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 458
T ++ EPEV R D+F++LA DG+W+ M +++ V
Sbjct: 211 -TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
Length = 324
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 36/165 (21%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
SG+TA + + N GDSR +L + + DH N E ER++
Sbjct: 125 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRK-----VHFFTQDHKPSNPLEKERIQ--- 176
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
A V R+ G L RA GD +K V GP
Sbjct: 177 ---NAGGSVMIQRVNGSLAVSRALGDFDYKC-------VHGKGP---------------- 210
Query: 415 HTPPYLTAEPEV-TYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 458
T ++ EPEV R D+F++LA DG+W+ M +++ V
Sbjct: 211 -TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 254
>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
Length = 455
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 36/165 (21%)
Query: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354
SG+TA + + N GDSR +L + + DH N E ER++
Sbjct: 198 SGSTAVGVLISPQHTYFINCGDSRGLLCRNRK-----VHFFTQDHKPSNPLEKERIQ--- 249
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414
A V R+ G L RA GD +K V GP
Sbjct: 250 ---NAGGSVMIQRVNGSLAVSRALGDFDYKC-------VHGKGP---------------- 283
Query: 415 HTPPYLTAEPEV-TYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 458
T ++ EPEV R D+F++LA DG+W+ M +++ V
Sbjct: 284 -TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFV 327
>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
Length = 247
Score = 43.5 bits (101), Expect = 5e-04
Identities = 55/203 (27%), Positives = 88/203 (43%), Gaps = 46/203 (22%)
Query: 296 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERE-LERLKLEH 354
G TA VA L++AN GDSRA+L ++E LS + + ER+ +++L +
Sbjct: 3 GCTALVAVSLQGKLYMANAGDSRAILVRRDE-----IRPLSFEFTPETERQRIQQLAFVY 57
Query: 355 PKSEAKSVVKQDRLLGLLMPFRAFGD-----VKFK------WSI------DLQKRVIESG 397
P+ A + L P R GD V F+ WS DL+ +I
Sbjct: 58 PELLAGEFTR------LEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQ 111
Query: 398 PDQ------------LNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP----QDKFLVLA 441
Q L D++ + + N P+L + P+VT + +D +V+A
Sbjct: 112 GRQARLLGTLAVSRGLGDHQL-RVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMA 170
Query: 442 TDGLWETMHRQDVVRIVGEYLTG 464
TDGLW+ + + V +V +L G
Sbjct: 171 TDGLWDVLSNEQVAWLVRSFLPG 193
>gi|5174703 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform alpha [Homo sapiens]
Length = 504
Score = 40.4 bits (93), Expect = 0.004
Identities = 48/160 (30%), Positives = 68/160 (42%), Gaps = 34/160 (21%)
Query: 296 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLK---L 352
GA A VA + L+VAN G +RA+L DG L+ DH +NE EL RL L
Sbjct: 165 GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG-LQVTQLNVDHTTENEDELFRLSQLGL 223
Query: 353 EHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPP 412
+ K +KQ ++ R GD K K+ YT
Sbjct: 224 DAGK------IKQVGIICGQESTRRIGDYKVKYG-------------------YTDIDLL 258
Query: 413 NYHTPPYLTAEPEVTYHRLRPQD---KFLVLATDGLWETM 449
+ + AEPE+ H +P D FLVL ++GL++ +
Sbjct: 259 SAAKSKPIIAEPEI--HGAQPLDGVTGFLVLMSEGLYKAL 296
>gi|41281798 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform beta [Homo sapiens]
Length = 462
Score = 40.4 bits (93), Expect = 0.004
Identities = 48/160 (30%), Positives = 68/160 (42%), Gaps = 34/160 (21%)
Query: 296 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLK---L 352
GA A VA + L+VAN G +RA+L DG L+ DH +NE EL RL L
Sbjct: 165 GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG-LQVTQLNVDHTTENEDELFRLSQLGL 223
Query: 353 EHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPP 412
+ K +KQ ++ R GD K K+ YT
Sbjct: 224 DAGK------IKQVGIICGQESTRRIGDYKVKYG-------------------YTDIDLL 258
Query: 413 NYHTPPYLTAEPEVTYHRLRPQD---KFLVLATDGLWETM 449
+ + AEPE+ H +P D FLVL ++GL++ +
Sbjct: 259 SAAKSKPIIAEPEI--HGAQPLDGVTGFLVLMSEGLYKAL 296
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 40.0 bits (92), Expect = 0.006
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 45/169 (26%)
Query: 296 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHP 355
G T V + G LHVA GDS+ ML + + AV L H E E +R++
Sbjct: 329 GTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQ-----AVELMKPHKPDREDEKQRIE---- 379
Query: 356 KSEAKSVVKQD--RLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPN 413
+ VV R+ G L RA GD + K
Sbjct: 380 -ALGGCVVWFGAWRVNGSLSVSRAIGDAEHK----------------------------- 409
Query: 414 YHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYL 462
PY+ + + L + +L+LA DG ++T++ + V++V ++L
Sbjct: 410 ----PYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHL 454
>gi|65301141 PH domain and leucine rich repeat protein
phosphatase-like [Homo sapiens]
Length = 1323
Score = 35.8 bits (81), Expect = 0.11
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
Query: 418 PYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYK 477
P++ +P ++ L QD+ L+L LWE + + V V H Q P+A
Sbjct: 960 PWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAV------RHVQDPLAAAKKL 1013
Query: 478 VTLGQMHG 485
TL Q +G
Sbjct: 1014 CTLAQSYG 1021
>gi|37221175 PH domain and leucine rich repeat protein phosphatase
[Homo sapiens]
Length = 1205
Score = 33.9 bits (76), Expect = 0.41
Identities = 14/41 (34%), Positives = 23/41 (56%)
Query: 418 PYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIV 458
P + P V L PQD+F +L + GLW+++ ++ V V
Sbjct: 837 PSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAV 877
>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
sapiens]
Length = 505
Score = 33.5 bits (75), Expect = 0.53
Identities = 72/325 (22%), Positives = 117/325 (36%), Gaps = 58/325 (17%)
Query: 166 GVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYF 225
G+FDGHAG ++ S L +I L + L+EI LP P
Sbjct: 155 GLFDGHAGGGAAEMASRLLHRHIREQL---KDLVEILQDPSPPPLCLPTT-----PGTPD 206
Query: 226 SKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFL 285
S + S L ++ W ++ S + V A+ NAF+ +D ++ E +
Sbjct: 207 SSDPSHLL--GPQSCWSSQKEV----SHESLVVGAVENAFQLMDEQMARERRGHQVEG-- 258
Query: 286 NYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNER 345
G A V ++VAN GDSRA++ E + +S + + ER
Sbjct: 259 ----------GCCALVVIYLLGKVYVANAGDSRAIIVRNGE-----IIPMSREFTPETER 303
Query: 346 ELERL--------------KLEHPKSEA------KSVVKQDRLLGLLMPFRAFGDVKFKW 385
+ +L LE P+ + + + + G D++F
Sbjct: 304 QRLQLLGFLKPELLGSEFTHLEFPRRVLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPL 363
Query: 386 SIDLQKR---VIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQ----DKFL 438
K+ + G + + K P+L+ PEV + L D L
Sbjct: 364 VCGEGKKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVL 423
Query: 439 VLATDGLWETMHRQDVVRIVGEYLT 463
VL TDGLW+ +V V L+
Sbjct: 424 VLGTDGLWDVTTDCEVAATVDRVLS 448
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,039,472
Number of Sequences: 37866
Number of extensions: 997365
Number of successful extensions: 2408
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2339
Number of HSP's gapped (non-prelim): 60
length of query: 562
length of database: 18,247,518
effective HSP length: 107
effective length of query: 455
effective length of database: 14,195,856
effective search space: 6459114480
effective search space used: 6459114480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.