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Search of human proteins with 239787094
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239787094 A20-binding inhibitor of NF-kappaB activation 2
isoform 2 [Homo sapiens]
(322 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239787094 A20-binding inhibitor of NF-kappaB activation 2 iso... 650 0.0
gi|239787092 A20-binding inhibitor of NF-kappaB activation 2 iso... 650 0.0
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 55 6e-08
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 55 8e-08
gi|223671870 inhibitor of kappa light polypeptide gene enhancer ... 55 1e-07
gi|4504631 inhibitor of kappa light polypeptide gene enhancer in... 55 1e-07
gi|153792133 inhibitor of kappa light polypeptide gene enhancer ... 55 1e-07
gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 52 7e-07
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 51 2e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 51 2e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 51 2e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 51 2e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 51 2e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 51 2e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 51 2e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 51 2e-06
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 49 5e-06
gi|4503593 epidermal growth factor receptor pathway substrate 15... 48 1e-05
gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens] 48 1e-05
gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens] 48 1e-05
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 48 1e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 48 1e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 48 1e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 48 1e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 48 1e-05
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 48 1e-05
gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo s... 48 1e-05
gi|229577185 epidermal growth factor receptor pathway substrate ... 47 2e-05
gi|16262452 cingulin [Homo sapiens] 47 3e-05
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 46 4e-05
>gi|239787094 A20-binding inhibitor of NF-kappaB activation 2
isoform 2 [Homo sapiens]
Length = 322
Score = 650 bits (1676), Expect = 0.0
Identities = 322/322 (100%), Positives = 322/322 (100%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQH
Sbjct: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW 120
LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW
Sbjct: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW 120
Query: 121 QRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRT 180
QRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRT
Sbjct: 121 QRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRT 180
Query: 181 ARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREP 240
ARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREP
Sbjct: 181 ARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREP 240
Query: 241 DAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPH 300
DAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPH
Sbjct: 241 DAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPH 300
Query: 301 CLQCFSDEQGEELLRHVAECCQ 322
CLQCFSDEQGEELLRHVAECCQ
Sbjct: 301 CLQCFSDEQGEELLRHVAECCQ 322
>gi|239787092 A20-binding inhibitor of NF-kappaB activation 2
isoform 1 [Homo sapiens]
Length = 429
Score = 650 bits (1676), Expect = 0.0
Identities = 322/322 (100%), Positives = 322/322 (100%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQH
Sbjct: 108 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQH 167
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW 120
LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW
Sbjct: 168 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW 227
Query: 121 QRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRT 180
QRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRT
Sbjct: 228 QRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRT 287
Query: 181 ARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREP 240
ARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREP
Sbjct: 288 ARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREP 347
Query: 241 DAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPH 300
DAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPH
Sbjct: 348 DAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPH 407
Query: 301 CLQCFSDEQGEELLRHVAECCQ 322
CLQCFSDEQGEELLRHVAECCQ
Sbjct: 408 CLQCFSDEQGEELLRHVAECCQ 429
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 55.5 bits (132), Expect = 6e-08
Identities = 71/285 (24%), Positives = 113/285 (39%), Gaps = 60/285 (21%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
++L Q Q + E E+ AE E RA + L H L + CQHL
Sbjct: 881 EKLQLQEQLQAETELC------AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHL 934
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRL--LKQKVTHVEDLNAK 119
E++ Q+N+ E E +Q +EK+ E +L L+++ +ED N K
Sbjct: 935 QA---EKKKMQQNIQELEEQLEEEESARQKLQ--LEKVTTEAKLKKLEEEQIILEDQNCK 989
Query: 120 WQRYNASRD----EYVRGLHAQ------LRGLQIPHEP------------ELMRKEISRL 157
+ + E+ L + L L+ HE E R+E+ +
Sbjct: 990 LAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKT 1049
Query: 158 NRQLEEKINDC-----------AEVKQELAASRTARDAALERVQ--------------ML 192
R+LE D AE+K +LA AAL RV+ L
Sbjct: 1050 RRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIREL 1109
Query: 193 EQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDS 237
E QI ++D SERA R +A+ + ++L E++ +L ++ DS
Sbjct: 1110 ESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDS 1154
Score = 44.7 bits (104), Expect = 1e-04
Identities = 46/246 (18%), Positives = 100/246 (40%), Gaps = 15/246 (6%)
Query: 12 REKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL----AKCLDE 67
+E+E+V +R E + L L E QL+ L A +C A+ +
Sbjct: 850 KEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAK 909
Query: 68 RQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASR 127
+Q + + E + +Q+ +K+Q+ + L++++ E K Q +
Sbjct: 910 KQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTT 969
Query: 128 DEYVRGLHAQL-----RGLQIPHEPELMRKEISRLNRQL---EEKINDCAEVKQELAASR 179
+ ++ L + + ++ E +L+ I+ L EEK A++K + A
Sbjct: 970 EAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMI 1029
Query: 180 TARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSRE 239
T + L R + Q++ + + D +I EL+ ++A L Q++ +++ +
Sbjct: 1030 TDLEERLRREEKQRQELEKTRRKLEGDSTD---LSDQIAELQAQIAELKMQLAKKEEELQ 1086
Query: 240 PDAGRI 245
R+
Sbjct: 1087 AALARV 1092
Score = 38.1 bits (87), Expect = 0.011
Identities = 32/121 (26%), Positives = 60/121 (49%), Gaps = 6/121 (4%)
Query: 109 KVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKIND- 167
KV + ++ + + A +E V+ QL E E ++ ++ QL+E++
Sbjct: 833 KVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAE 892
Query: 168 ---CAEVKQELAASRTARDAALERV-QMLEQQILAYKDDFMSERADRERAQSRIQELEEK 223
CAE +EL A TA+ LE + LE ++ ++ +A++++ Q IQELEE+
Sbjct: 893 TELCAEA-EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQ 951
Query: 224 V 224
+
Sbjct: 952 L 952
Score = 36.2 bits (82), Expect = 0.040
Identities = 69/305 (22%), Positives = 117/305 (38%), Gaps = 52/305 (17%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
M+Q SQ E +++ +R A E+A+ + LANE L + + H +
Sbjct: 1190 MRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKK 1249
Query: 61 LAKCLDERQHAQRNVGER--------------------------SPDQSEHTDGHTSVQS 94
+ L E Q + N GER S+ T ++++S
Sbjct: 1250 VEAQLQELQ-VKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES 1308
Query: 95 VI----EKLQEENR---LLKQKVTHVEDLNAKWQRYNASRDE-------YVRGLHAQLRG 140
+ E LQEENR L K+ VED ++ +E + LHAQ+
Sbjct: 1309 QLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVAD 1368
Query: 141 LQIPHEPELMRKEIS-RLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAY 199
++ E + E + + R+L++ + ++ +E A+ + R+Q +L
Sbjct: 1369 MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVD 1428
Query: 200 KDDFMSERADRERAQSRIQEL--EEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLA- 256
D + E+ Q + +L EEK S + + E D A K K L+
Sbjct: 1429 LDHQRQSACNLEKKQKKFDQLLAEEKTISAKY-------AEERDRAEAEAREKETKALSL 1481
Query: 257 ADALE 261
A ALE
Sbjct: 1482 ARALE 1486
Score = 35.4 bits (80), Expect = 0.069
Identities = 32/159 (20%), Positives = 68/159 (42%), Gaps = 1/159 (0%)
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A+ DER+ V R + + D + S + E + L++ ++D +
Sbjct: 1596 AELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELD 1655
Query: 122 RYNASRDEYVRGLHAQLRGLQ-IPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRT 180
ASR+E + + L+ + E +++E++ R + + E+ E+A S
Sbjct: 1656 DTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSG 1715
Query: 181 ARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQE 219
ALE + LE +I +++ E+ + E R+++
Sbjct: 1716 KGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKK 1754
Score = 33.1 bits (74), Expect = 0.34
Identities = 47/237 (19%), Positives = 94/237 (39%), Gaps = 15/237 (6%)
Query: 11 EREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRR----TLTATAHMCQHLAKCLD 66
E E ++ L+ + +R ++ R L E L+ TL +TA + +K
Sbjct: 1108 ELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 67 ERQHAQRNVGERSPD-QSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNA 125
E ++ + E + +++ + +E+L E+ K+ ++E Q
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK---QTLEN 1224
Query: 126 SRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAA 185
R E + L+G + E RK++ ++L+ K N+ V+ ELA T
Sbjct: 1225 ERGELANEVKVLLQG---KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVE 1281
Query: 186 LERVQML----EQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSR 238
L+ V L + + DF + + + Q +QE + SL ++ +D +
Sbjct: 1282 LDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEK 1338
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 55.1 bits (131), Expect = 8e-08
Identities = 62/237 (26%), Positives = 103/237 (43%), Gaps = 51/237 (21%)
Query: 13 EKEVVLLRRSMAEGERARAASDVLCRSLANETHQ----LRRTLTATAHMCQHLAKCLDER 68
EK+V +L + +E D RS+ + Q LR+ L A + + + ER
Sbjct: 300 EKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKL---ADLQKQVTDLEAER 356
Query: 69 QHAQRNVGER-----SPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRY 123
+ QR+ + S + E TD E+L E + L+QKV +++D
Sbjct: 357 EQKQRDFDRKLLLAKSKIEMEETDK--------EQLTAEAKELRQKVKYLQD-------- 400
Query: 124 NASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKIN--------DCAEVKQEL 175
QL L + E KEI RLN+ LEE ++ A E
Sbjct: 401 -------------QLSPLT--RQREYQEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEG 445
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVS 232
A + + + + ++L+QQ+ +++DF ER+DRER +EL+++V L QV+
Sbjct: 446 AGALLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVT 502
Score = 36.2 bits (82), Expect = 0.040
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 157 LNRQLEEKINDCAEVKQELAASRTARDAALERVQM-LEQQILAYKDDFMSERADRERAQS 215
+ +Q E+KI + + +L T +A E+ Q ++++L K E D+E+ +
Sbjct: 327 MKQQYEQKITELRQKLADLQKQVTDLEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTA 386
Query: 216 RIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQ 275
+EL +KV L Q+S RE I +K + +AL + P P T
Sbjct: 387 EAKELRQKVKYLQDQLSPLTRQREYQEKEIQRLNKALE----EALSIQTPPS-SPPTAFG 441
Query: 276 QPE 278
PE
Sbjct: 442 SPE 444
>gi|223671870 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform b [Homo sapiens]
Length = 487
Score = 54.7 bits (130), Expect = 1e-07
Identities = 73/334 (21%), Positives = 130/334 (38%), Gaps = 44/334 (13%)
Query: 5 LSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL-AK 63
L + + + +EV L+R + +A+ SL E + + L A CQ L +
Sbjct: 182 LKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGR 241
Query: 64 CLDERQHAQRNVGERSPDQSEHTDGHTSV----QSVIEKLQEENRLLKQKVTHVEDLNAK 119
+ A++ ER Q +H+ + QSV L+ E + ++ + L
Sbjct: 242 ARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVA 301
Query: 120 WQRYNASRDEYVRGL---HAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ + D +++ + RG+Q+ +++ + +Q EE + EV +L
Sbjct: 302 YHQLFQEYDNHIKSSVVGSERKRGMQL--------EDLKQQLQQAEEALVAKQEVIDKLK 353
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQ-----V 231
+E V +L+ Q YK DF +ER RE+ + + L+E++ L +
Sbjct: 354 EEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKA 413
Query: 232 SWRQDSREPDAGRIHAGSKTAKYLAADAL---ELMVPGGWRPGTGSQQPEPPAEGGHPGA 288
S ++ +R D + H A A A L +P SQ+ PP E
Sbjct: 414 SCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALP--------SQRRSPPEE------ 459
Query: 289 AQRGQGDLQCPHCLQCFSDEQGEELLRHVAECCQ 322
D CP C + + L HV EC +
Sbjct: 460 ----PPDFCCPKCQ--YQAPDMDTLQIHVMECIE 487
>gi|4504631 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform a [Homo sapiens]
Length = 419
Score = 54.7 bits (130), Expect = 1e-07
Identities = 73/334 (21%), Positives = 130/334 (38%), Gaps = 44/334 (13%)
Query: 5 LSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL-AK 63
L + + + +EV L+R + +A+ SL E + + L A CQ L +
Sbjct: 114 LKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGR 173
Query: 64 CLDERQHAQRNVGERSPDQSEHTDGHTSV----QSVIEKLQEENRLLKQKVTHVEDLNAK 119
+ A++ ER Q +H+ + QSV L+ E + ++ + L
Sbjct: 174 ARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVA 233
Query: 120 WQRYNASRDEYVRGL---HAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ + D +++ + RG+Q+ +++ + +Q EE + EV +L
Sbjct: 234 YHQLFQEYDNHIKSSVVGSERKRGMQL--------EDLKQQLQQAEEALVAKQEVIDKLK 285
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQ-----V 231
+E V +L+ Q YK DF +ER RE+ + + L+E++ L +
Sbjct: 286 EEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKA 345
Query: 232 SWRQDSREPDAGRIHAGSKTAKYLAADAL---ELMVPGGWRPGTGSQQPEPPAEGGHPGA 288
S ++ +R D + H A A A L +P SQ+ PP E
Sbjct: 346 SCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALP--------SQRRSPPEE------ 391
Query: 289 AQRGQGDLQCPHCLQCFSDEQGEELLRHVAECCQ 322
D CP C + + L HV EC +
Sbjct: 392 ----PPDFCCPKCQ--YQAPDMDTLQIHVMECIE 419
>gi|153792133 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform a [Homo sapiens]
Length = 419
Score = 54.7 bits (130), Expect = 1e-07
Identities = 73/334 (21%), Positives = 130/334 (38%), Gaps = 44/334 (13%)
Query: 5 LSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL-AK 63
L + + + +EV L+R + +A+ SL E + + L A CQ L +
Sbjct: 114 LKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGR 173
Query: 64 CLDERQHAQRNVGERSPDQSEHTDGHTSV----QSVIEKLQEENRLLKQKVTHVEDLNAK 119
+ A++ ER Q +H+ + QSV L+ E + ++ + L
Sbjct: 174 ARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVA 233
Query: 120 WQRYNASRDEYVRGL---HAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ + D +++ + RG+Q+ +++ + +Q EE + EV +L
Sbjct: 234 YHQLFQEYDNHIKSSVVGSERKRGMQL--------EDLKQQLQQAEEALVAKQEVIDKLK 285
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQ-----V 231
+E V +L+ Q YK DF +ER RE+ + + L+E++ L +
Sbjct: 286 EEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKA 345
Query: 232 SWRQDSREPDAGRIHAGSKTAKYLAADAL---ELMVPGGWRPGTGSQQPEPPAEGGHPGA 288
S ++ +R D + H A A A L +P SQ+ PP E
Sbjct: 346 SCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALP--------SQRRSPPEE------ 391
Query: 289 AQRGQGDLQCPHCLQCFSDEQGEELLRHVAECCQ 322
D CP C + + L HV EC +
Sbjct: 392 ----PPDFCCPKCQ--YQAPDMDTLQIHVMECIE 419
>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
Length = 1001
Score = 52.0 bits (123), Expect = 7e-07
Identities = 58/274 (21%), Positives = 115/274 (41%), Gaps = 21/274 (7%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANE---THQLRRTLTATAHM 57
+Q+ L ++E V + + ++ R + +L LA E T +LR+ L + +
Sbjct: 641 LQRELQSLSQRLQREFVPKPEAQVQLQQLRQSVGLLTNELAMEKEATEKLRKLLASQSSG 700
Query: 58 CQHLAKCLDERQHAQRNVGERSPDQSEH--------TDGHTSVQSVIEKLQEENRLLKQK 109
+ L CL +R+ ++ + E D H Q V+ +LQEEN+ L+
Sbjct: 701 LRGLWDCLPADLVGERSAQSKAAESLEELRACISTLVDRHREAQQVLARLQEENQQLRGS 760
Query: 110 VTHVED----LNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKI 165
++ + L A A+ ++ + L +LR +Q + +EI +L + L +
Sbjct: 761 LSPCREPGTSLKAPASPQVAALEQDLGKLEEELRAVQATMSGK--SQEIGKLKQLLYQAT 818
Query: 166 NDCAEVKQELAAS----RTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELE 221
+ AE++ AAS R + + + Q Q++ A + + + + R + + E
Sbjct: 819 EEVAELRAREAASLRQHEKTRGSLVAQAQAWGQELKALLEKYNTACREVGRLREAVAEER 878
Query: 222 EKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYL 255
+ L Q + ++ GR KTA+ L
Sbjct: 879 RRSGDLAAQAAEQERQASEMRGRSEQFEKTAELL 912
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 34/272 (12%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDV--LCRSLANETHQLRRTLTATAHMC 58
MQ + + + E E++ ++ +A+ + R D + + LA ET +RTL A
Sbjct: 2316 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAER--- 2372
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDG----HTSVQSVIEKLQEENRLLKQKVTHVE 114
Q + E + + V E S Q+ + + + EKL ++KVT V+
Sbjct: 2373 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ 2432
Query: 115 DLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQE 174
L + Q Q H+ E +R+ I+ L R+ E+ + ++ +
Sbjct: 2433 TLEIQRQ--------------------QSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2472
Query: 175 LAASRTAR-DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE----KVASLLH 229
+T + + L+ Q L+Q L+ KD + E+ ++++++L + K L
Sbjct: 2473 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLRE 2532
Query: 230 QVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
+ +Q E + R+ A + A+ +A E
Sbjct: 2533 EQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2564
Score = 38.1 bits (87), Expect = 0.011
Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 11/258 (4%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEG----ERARAASDVLCRSLANETHQLRRTLTATAH 56
+Q L Q E E+ R S AE ER+ V L E + R A A
Sbjct: 1563 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER-RAQQQAEAE 1621
Query: 57 MCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSV-QSVIEKLQEENRLLKQKVTHVED 115
+ A+ ER + N R Q+E S+ Q+ EK +EE ++ E+
Sbjct: 1622 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1681
Query: 116 LNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+ + E R L ++ E EL+R L + E+ +++EL
Sbjct: 1682 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR-----LRAETEQGEQQRQLLEEEL 1736
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQ 235
A + AA ++ Q LE ++ + + A + RA+ + EK L + R
Sbjct: 1737 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 236 DSREPDAGRIHAGSKTAK 253
+A R+ A ++ AK
Sbjct: 1797 RELAEEAARLRALAEEAK 1814
Score = 35.8 bits (81), Expect = 0.053
Identities = 69/333 (20%), Positives = 133/333 (39%), Gaps = 44/333 (13%)
Query: 13 EKEVVLLRRSMAEGE--RARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQH 70
E E VL + A GE R + +++ + E +LRR A + L E Q
Sbjct: 1830 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL-----EEQA 1884
Query: 71 AQR--NVGERSPDQSEHTDGHTSVQS-VIEKLQEENRLLKQKVTHVE-----------DL 116
AQ ++ ER + +D Q ++E + R +++++ ++ +L
Sbjct: 1885 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1944
Query: 117 NAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ R ++ ++ +R + L+ + +L +E R R+ EE++ ++E A
Sbjct: 1945 ELELGRIRSNAEDTLRS--KEQAELEAARQRQLAAEE-ERRRREAEERVQKSLAAEEEAA 2001
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERAD----------RERAQSRIQELEEKVAS 226
R AALE V+ L+ ++ + + ERA+ +E AQ R+Q E+ A
Sbjct: 2002 RQ---RKAALEEVERLKAKVEEARR--LRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2056
Query: 227 LLHQ----VSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAE 282
+ Q + + ++ ++ A+ A +A E V R S++ AE
Sbjct: 2057 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE-REAAQSRRQVEEAE 2115
Query: 283 GGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLR 315
A ++ Q Q + E +E R
Sbjct: 2116 RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148
Score = 35.0 bits (79), Expect = 0.090
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 32/230 (13%)
Query: 9 QHEREKEVVLLRRSMAEGERARA-ASDVLCRSLANETHQLRRT---------LTATAHMC 58
+ + E E R+ AE ER R A + + +SLA E R+ L A
Sbjct: 1962 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 2021
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNA 118
+ L + ++ Q + + + + + +V +K QE + L+Q+ + ++ L
Sbjct: 2022 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2081
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEIS---RLNRQLEEKINDCA------ 169
+ + + +E A+ +Q E R+++ RL + EE+ A
Sbjct: 2082 EAEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA 2135
Query: 170 -----EVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQ 214
E +QE A A AAL + Q + ++ +K +E+ R++AQ
Sbjct: 2136 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK--FAEQTLRQKAQ 2183
Score = 32.7 bits (73), Expect = 0.44
Identities = 46/254 (18%), Positives = 104/254 (40%), Gaps = 11/254 (4%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLAN-ETHQLRRTLTATAHMCQH 60
++ L++ Q E+E + + E +R A + ++ A E +L++ + +
Sbjct: 1347 EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1406
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAK- 119
A + Q +R++ E + ++ ++ + E +RL ++ V L +
Sbjct: 1407 AAV---DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1463
Query: 120 WQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASR 179
+R + ++ L A R + + ++E RL RQ++++ + + ELA+
Sbjct: 1464 TERQRGGAEGELQALRA--RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1521
Query: 180 TARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSRE 239
A A Q Q + + +E A+R Q+ ++ + +L + + R E
Sbjct: 1522 KAEAEAAREKQRALQALEELR--LQAEEAERRLRQAEVERARQVQVAL--ETAQRSAEAE 1577
Query: 240 PDAGRIHAGSKTAK 253
+ R KTA+
Sbjct: 1578 LQSKRASFAEKTAQ 1591
Score = 32.3 bits (72), Expect = 0.58
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 26/244 (10%)
Query: 7 QPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLD 66
Q Q E E L+ +AE RA+A ++ + + ++ L T Q L
Sbjct: 2373 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT-LV 2431
Query: 67 ERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW--QRYN 124
+ QR + D + ++ EKLQ+E +LL+ K ++ + + Q
Sbjct: 2432 QTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2489
Query: 125 ASRDEYVRGLHAQLRGLQIPHEP-----ELMRKEISRLNRQLEEKINDCAEVKQE----L 175
A + ++ + L+ + + +L + E+++ + EE+ +++QE +
Sbjct: 2490 ALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLV 2549
Query: 176 AASRTAR----------DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
A+ AR E +Q LEQQ +++ ++E R R Q ++ E E+ A
Sbjct: 2550 ASMEEARRRQHEAEEGVRRKQEELQQLEQQ-RRQQEELLAEENQRLREQLQLLE-EQHRA 2607
Query: 226 SLLH 229
+L H
Sbjct: 2608 ALAH 2611
Score = 29.3 bits (64), Expect = 4.9
Identities = 72/355 (20%), Positives = 119/355 (33%), Gaps = 52/355 (14%)
Query: 5 LSQPQHEREKEVVLLRRSMAE----GERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
L Q ER+ EV R +A+ + A +DV R L QL R L
Sbjct: 1163 LQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQREL----EQLGRQLRYYRESADP 1218
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVI--------EKLQEENRLLKQKVTH 112
L L + + Q + S+ + + EK++E R KQ +
Sbjct: 1219 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1278
Query: 113 VEDLNAKWQRYNASRD--------------------EYV--RGLHAQLRGLQ------IP 144
++D + Y A + EYV R +++L L I
Sbjct: 1279 IKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFIS 1338
Query: 145 HEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFM 204
M +E +Q E+ AEV+ L R +A + E++ +
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 205 SERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMV 264
E RE A Q+ + + L Q+ R+ I A ++ A+ AA+ L +
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQL------RQSSEAEIQAKARQAE--AAERSRLRI 1450
Query: 265 PGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAE 319
R + GG G Q + + + + E+ E L R V +
Sbjct: 1451 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505
Score = 28.5 bits (62), Expect = 8.4
Identities = 38/218 (17%), Positives = 85/218 (38%), Gaps = 14/218 (6%)
Query: 5 LSQPQHER---EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
L + H++ ++E+ L+ E R R+ + S+ + +L + ++
Sbjct: 2195 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE--AENR 2252
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A L ++ + QR + E + + + + ++ +L ++ + L K
Sbjct: 2253 ALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKML 2312
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA 181
+ + L A+ LQ + EL +++ RL E+ + Q+LA
Sbjct: 2313 KEKMQAVQEATRLKAEAELLQ--QQKELAQEQARRLQEDKEQ-------MAQQLAEETQG 2363
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQE 219
LE + + ++ A + A+ RAQ+R +E
Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2401
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 34/272 (12%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDV--LCRSLANETHQLRRTLTATAHMC 58
MQ + + + E E++ ++ +A+ + R D + + LA ET +RTL A
Sbjct: 2320 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAER--- 2376
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDG----HTSVQSVIEKLQEENRLLKQKVTHVE 114
Q + E + + V E S Q+ + + + EKL ++KVT V+
Sbjct: 2377 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ 2436
Query: 115 DLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQE 174
L + Q Q H+ E +R+ I+ L R+ E+ + ++ +
Sbjct: 2437 TLEIQRQ--------------------QSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2476
Query: 175 LAASRTAR-DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE----KVASLLH 229
+T + + L+ Q L+Q L+ KD + E+ ++++++L + K L
Sbjct: 2477 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLRE 2536
Query: 230 QVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
+ +Q E + R+ A + A+ +A E
Sbjct: 2537 EQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2568
Score = 38.1 bits (87), Expect = 0.011
Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 11/258 (4%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEG----ERARAASDVLCRSLANETHQLRRTLTATAH 56
+Q L Q E E+ R S AE ER+ V L E + R A A
Sbjct: 1567 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER-RAQQQAEAE 1625
Query: 57 MCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSV-QSVIEKLQEENRLLKQKVTHVED 115
+ A+ ER + N R Q+E S+ Q+ EK +EE ++ E+
Sbjct: 1626 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1685
Query: 116 LNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+ + E R L ++ E EL+R L + E+ +++EL
Sbjct: 1686 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR-----LRAETEQGEQQRQLLEEEL 1740
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQ 235
A + AA ++ Q LE ++ + + A + RA+ + EK L + R
Sbjct: 1741 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1800
Query: 236 DSREPDAGRIHAGSKTAK 253
+A R+ A ++ AK
Sbjct: 1801 RELAEEAARLRALAEEAK 1818
Score = 35.8 bits (81), Expect = 0.053
Identities = 69/333 (20%), Positives = 133/333 (39%), Gaps = 44/333 (13%)
Query: 13 EKEVVLLRRSMAEGE--RARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQH 70
E E VL + A GE R + +++ + E +LRR A + L E Q
Sbjct: 1834 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL-----EEQA 1888
Query: 71 AQR--NVGERSPDQSEHTDGHTSVQS-VIEKLQEENRLLKQKVTHVE-----------DL 116
AQ ++ ER + +D Q ++E + R +++++ ++ +L
Sbjct: 1889 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1948
Query: 117 NAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ R ++ ++ +R + L+ + +L +E R R+ EE++ ++E A
Sbjct: 1949 ELELGRIRSNAEDTLRS--KEQAELEAARQRQLAAEE-ERRRREAEERVQKSLAAEEEAA 2005
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERAD----------RERAQSRIQELEEKVAS 226
R AALE V+ L+ ++ + + ERA+ +E AQ R+Q E+ A
Sbjct: 2006 RQ---RKAALEEVERLKAKVEEARR--LRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2060
Query: 227 LLHQ----VSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAE 282
+ Q + + ++ ++ A+ A +A E V R S++ AE
Sbjct: 2061 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE-REAAQSRRQVEEAE 2119
Query: 283 GGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLR 315
A ++ Q Q + E +E R
Sbjct: 2120 RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2152
Score = 35.0 bits (79), Expect = 0.090
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 32/230 (13%)
Query: 9 QHEREKEVVLLRRSMAEGERARA-ASDVLCRSLANETHQLRRT---------LTATAHMC 58
+ + E E R+ AE ER R A + + +SLA E R+ L A
Sbjct: 1966 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 2025
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNA 118
+ L + ++ Q + + + + + +V +K QE + L+Q+ + ++ L
Sbjct: 2026 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2085
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEIS---RLNRQLEEKINDCA------ 169
+ + + +E A+ +Q E R+++ RL + EE+ A
Sbjct: 2086 EAEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA 2139
Query: 170 -----EVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQ 214
E +QE A A AAL + Q + ++ +K +E+ R++AQ
Sbjct: 2140 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK--FAEQTLRQKAQ 2187
Score = 32.7 bits (73), Expect = 0.44
Identities = 46/254 (18%), Positives = 104/254 (40%), Gaps = 11/254 (4%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLAN-ETHQLRRTLTATAHMCQH 60
++ L++ Q E+E + + E +R A + ++ A E +L++ + +
Sbjct: 1351 EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1410
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAK- 119
A + Q +R++ E + ++ ++ + E +RL ++ V L +
Sbjct: 1411 AAV---DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1467
Query: 120 WQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASR 179
+R + ++ L A R + + ++E RL RQ++++ + + ELA+
Sbjct: 1468 TERQRGGAEGELQALRA--RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1525
Query: 180 TARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSRE 239
A A Q Q + + +E A+R Q+ ++ + +L + + R E
Sbjct: 1526 KAEAEAAREKQRALQALEELR--LQAEEAERRLRQAEVERARQVQVAL--ETAQRSAEAE 1581
Query: 240 PDAGRIHAGSKTAK 253
+ R KTA+
Sbjct: 1582 LQSKRASFAEKTAQ 1595
Score = 32.3 bits (72), Expect = 0.58
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 26/244 (10%)
Query: 7 QPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLD 66
Q Q E E L+ +AE RA+A ++ + + ++ L T Q L
Sbjct: 2377 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT-LV 2435
Query: 67 ERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW--QRYN 124
+ QR + D + ++ EKLQ+E +LL+ K ++ + + Q
Sbjct: 2436 QTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2493
Query: 125 ASRDEYVRGLHAQLRGLQIPHEP-----ELMRKEISRLNRQLEEKINDCAEVKQE----L 175
A + ++ + L+ + + +L + E+++ + EE+ +++QE +
Sbjct: 2494 ALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLV 2553
Query: 176 AASRTAR----------DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
A+ AR E +Q LEQQ +++ ++E R R Q ++ E E+ A
Sbjct: 2554 ASMEEARRRQHEAEEGVRRKQEELQQLEQQ-RRQQEELLAEENQRLREQLQLLE-EQHRA 2611
Query: 226 SLLH 229
+L H
Sbjct: 2612 ALAH 2615
Score = 29.3 bits (64), Expect = 4.9
Identities = 72/355 (20%), Positives = 119/355 (33%), Gaps = 52/355 (14%)
Query: 5 LSQPQHEREKEVVLLRRSMAE----GERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
L Q ER+ EV R +A+ + A +DV R L QL R L
Sbjct: 1167 LQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQREL----EQLGRQLRYYRESADP 1222
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVI--------EKLQEENRLLKQKVTH 112
L L + + Q + S+ + + EK++E R KQ +
Sbjct: 1223 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1282
Query: 113 VEDLNAKWQRYNASRD--------------------EYV--RGLHAQLRGLQ------IP 144
++D + Y A + EYV R +++L L I
Sbjct: 1283 IKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFIS 1342
Query: 145 HEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFM 204
M +E +Q E+ AEV+ L R +A + E++ +
Sbjct: 1343 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1402
Query: 205 SERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMV 264
E RE A Q+ + + L Q+ R+ I A ++ A+ AA+ L +
Sbjct: 1403 EEVVRREEAAVDAQQQKRSIQEELQQL------RQSSEAEIQAKARQAE--AAERSRLRI 1454
Query: 265 PGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAE 319
R + GG G Q + + + + E+ E L R V +
Sbjct: 1455 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1509
Score = 28.5 bits (62), Expect = 8.4
Identities = 38/218 (17%), Positives = 85/218 (38%), Gaps = 14/218 (6%)
Query: 5 LSQPQHER---EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
L + H++ ++E+ L+ E R R+ + S+ + +L + ++
Sbjct: 2199 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE--AENR 2256
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A L ++ + QR + E + + + + ++ +L ++ + L K
Sbjct: 2257 ALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKML 2316
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA 181
+ + L A+ LQ + EL +++ RL E+ + Q+LA
Sbjct: 2317 KEKMQAVQEATRLKAEAELLQ--QQKELAQEQARRLQEDKEQ-------MAQQLAEETQG 2367
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQE 219
LE + + ++ A + A+ RAQ+R +E
Sbjct: 2368 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2405
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 34/272 (12%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDV--LCRSLANETHQLRRTLTATAHMC 58
MQ + + + E E++ ++ +A+ + R D + + LA ET +RTL A
Sbjct: 2316 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAER--- 2372
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDG----HTSVQSVIEKLQEENRLLKQKVTHVE 114
Q + E + + V E S Q+ + + + EKL ++KVT V+
Sbjct: 2373 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ 2432
Query: 115 DLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQE 174
L + Q Q H+ E +R+ I+ L R+ E+ + ++ +
Sbjct: 2433 TLEIQRQ--------------------QSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2472
Query: 175 LAASRTAR-DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE----KVASLLH 229
+T + + L+ Q L+Q L+ KD + E+ ++++++L + K L
Sbjct: 2473 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLRE 2532
Query: 230 QVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
+ +Q E + R+ A + A+ +A E
Sbjct: 2533 EQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2564
Score = 38.1 bits (87), Expect = 0.011
Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 11/258 (4%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEG----ERARAASDVLCRSLANETHQLRRTLTATAH 56
+Q L Q E E+ R S AE ER+ V L E + R A A
Sbjct: 1563 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER-RAQQQAEAE 1621
Query: 57 MCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSV-QSVIEKLQEENRLLKQKVTHVED 115
+ A+ ER + N R Q+E S+ Q+ EK +EE ++ E+
Sbjct: 1622 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1681
Query: 116 LNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+ + E R L ++ E EL+R L + E+ +++EL
Sbjct: 1682 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR-----LRAETEQGEQQRQLLEEEL 1736
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQ 235
A + AA ++ Q LE ++ + + A + RA+ + EK L + R
Sbjct: 1737 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 236 DSREPDAGRIHAGSKTAK 253
+A R+ A ++ AK
Sbjct: 1797 RELAEEAARLRALAEEAK 1814
Score = 35.8 bits (81), Expect = 0.053
Identities = 69/333 (20%), Positives = 133/333 (39%), Gaps = 44/333 (13%)
Query: 13 EKEVVLLRRSMAEGE--RARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQH 70
E E VL + A GE R + +++ + E +LRR A + L E Q
Sbjct: 1830 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL-----EEQA 1884
Query: 71 AQR--NVGERSPDQSEHTDGHTSVQS-VIEKLQEENRLLKQKVTHVE-----------DL 116
AQ ++ ER + +D Q ++E + R +++++ ++ +L
Sbjct: 1885 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1944
Query: 117 NAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ R ++ ++ +R + L+ + +L +E R R+ EE++ ++E A
Sbjct: 1945 ELELGRIRSNAEDTLRS--KEQAELEAARQRQLAAEE-ERRRREAEERVQKSLAAEEEAA 2001
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERAD----------RERAQSRIQELEEKVAS 226
R AALE V+ L+ ++ + + ERA+ +E AQ R+Q E+ A
Sbjct: 2002 RQ---RKAALEEVERLKAKVEEARR--LRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2056
Query: 227 LLHQ----VSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAE 282
+ Q + + ++ ++ A+ A +A E V R S++ AE
Sbjct: 2057 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE-REAAQSRRQVEEAE 2115
Query: 283 GGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLR 315
A ++ Q Q + E +E R
Sbjct: 2116 RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148
Score = 35.0 bits (79), Expect = 0.090
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 32/230 (13%)
Query: 9 QHEREKEVVLLRRSMAEGERARA-ASDVLCRSLANETHQLRRT---------LTATAHMC 58
+ + E E R+ AE ER R A + + +SLA E R+ L A
Sbjct: 1962 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 2021
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNA 118
+ L + ++ Q + + + + + +V +K QE + L+Q+ + ++ L
Sbjct: 2022 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2081
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEIS---RLNRQLEEKINDCA------ 169
+ + + +E A+ +Q E R+++ RL + EE+ A
Sbjct: 2082 EAEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA 2135
Query: 170 -----EVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQ 214
E +QE A A AAL + Q + ++ +K +E+ R++AQ
Sbjct: 2136 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK--FAEQTLRQKAQ 2183
Score = 32.7 bits (73), Expect = 0.44
Identities = 46/254 (18%), Positives = 104/254 (40%), Gaps = 11/254 (4%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLAN-ETHQLRRTLTATAHMCQH 60
++ L++ Q E+E + + E +R A + ++ A E +L++ + +
Sbjct: 1347 EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1406
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAK- 119
A + Q +R++ E + ++ ++ + E +RL ++ V L +
Sbjct: 1407 AAV---DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1463
Query: 120 WQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASR 179
+R + ++ L A R + + ++E RL RQ++++ + + ELA+
Sbjct: 1464 TERQRGGAEGELQALRA--RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1521
Query: 180 TARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSRE 239
A A Q Q + + +E A+R Q+ ++ + +L + + R E
Sbjct: 1522 KAEAEAAREKQRALQALEELR--LQAEEAERRLRQAEVERARQVQVAL--ETAQRSAEAE 1577
Query: 240 PDAGRIHAGSKTAK 253
+ R KTA+
Sbjct: 1578 LQSKRASFAEKTAQ 1591
Score = 32.3 bits (72), Expect = 0.58
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 26/244 (10%)
Query: 7 QPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLD 66
Q Q E E L+ +AE RA+A ++ + + ++ L T Q L
Sbjct: 2373 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT-LV 2431
Query: 67 ERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW--QRYN 124
+ QR + D + ++ EKLQ+E +LL+ K ++ + + Q
Sbjct: 2432 QTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2489
Query: 125 ASRDEYVRGLHAQLRGLQIPHEP-----ELMRKEISRLNRQLEEKINDCAEVKQE----L 175
A + ++ + L+ + + +L + E+++ + EE+ +++QE +
Sbjct: 2490 ALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLV 2549
Query: 176 AASRTAR----------DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
A+ AR E +Q LEQQ +++ ++E R R Q ++ E E+ A
Sbjct: 2550 ASMEEARRRQHEAEEGVRRKQEELQQLEQQ-RRQQEELLAEENQRLREQLQLLE-EQHRA 2607
Query: 226 SLLH 229
+L H
Sbjct: 2608 ALAH 2611
Score = 29.3 bits (64), Expect = 4.9
Identities = 72/355 (20%), Positives = 119/355 (33%), Gaps = 52/355 (14%)
Query: 5 LSQPQHEREKEVVLLRRSMAE----GERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
L Q ER+ EV R +A+ + A +DV R L QL R L
Sbjct: 1163 LQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQREL----EQLGRQLRYYRESADP 1218
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVI--------EKLQEENRLLKQKVTH 112
L L + + Q + S+ + + EK++E R KQ +
Sbjct: 1219 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1278
Query: 113 VEDLNAKWQRYNASRD--------------------EYV--RGLHAQLRGLQ------IP 144
++D + Y A + EYV R +++L L I
Sbjct: 1279 IKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFIS 1338
Query: 145 HEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFM 204
M +E +Q E+ AEV+ L R +A + E++ +
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 205 SERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMV 264
E RE A Q+ + + L Q+ R+ I A ++ A+ AA+ L +
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQL------RQSSEAEIQAKARQAE--AAERSRLRI 1450
Query: 265 PGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAE 319
R + GG G Q + + + + E+ E L R V +
Sbjct: 1451 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505
Score = 28.5 bits (62), Expect = 8.4
Identities = 38/218 (17%), Positives = 85/218 (38%), Gaps = 14/218 (6%)
Query: 5 LSQPQHER---EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
L + H++ ++E+ L+ E R R+ + S+ + +L + ++
Sbjct: 2195 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE--AENR 2252
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A L ++ + QR + E + + + + ++ +L ++ + L K
Sbjct: 2253 ALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKML 2312
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA 181
+ + L A+ LQ + EL +++ RL E+ + Q+LA
Sbjct: 2313 KEKMQAVQEATRLKAEAELLQ--QQKELAQEQARRLQEDKEQ-------MAQQLAEETQG 2363
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQE 219
LE + + ++ A + A+ RAQ+R +E
Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2401
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 34/272 (12%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDV--LCRSLANETHQLRRTLTATAHMC 58
MQ + + + E E++ ++ +A+ + R D + + LA ET +RTL A
Sbjct: 2284 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAER--- 2340
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDG----HTSVQSVIEKLQEENRLLKQKVTHVE 114
Q + E + + V E S Q+ + + + EKL ++KVT V+
Sbjct: 2341 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ 2400
Query: 115 DLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQE 174
L + Q Q H+ E +R+ I+ L R+ E+ + ++ +
Sbjct: 2401 TLEIQRQ--------------------QSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2440
Query: 175 LAASRTAR-DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE----KVASLLH 229
+T + + L+ Q L+Q L+ KD + E+ ++++++L + K L
Sbjct: 2441 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLRE 2500
Query: 230 QVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
+ +Q E + R+ A + A+ +A E
Sbjct: 2501 EQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2532
Score = 38.1 bits (87), Expect = 0.011
Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 11/258 (4%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEG----ERARAASDVLCRSLANETHQLRRTLTATAH 56
+Q L Q E E+ R S AE ER+ V L E + R A A
Sbjct: 1531 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER-RAQQQAEAE 1589
Query: 57 MCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSV-QSVIEKLQEENRLLKQKVTHVED 115
+ A+ ER + N R Q+E S+ Q+ EK +EE ++ E+
Sbjct: 1590 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1649
Query: 116 LNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+ + E R L ++ E EL+R L + E+ +++EL
Sbjct: 1650 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR-----LRAETEQGEQQRQLLEEEL 1704
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQ 235
A + AA ++ Q LE ++ + + A + RA+ + EK L + R
Sbjct: 1705 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1764
Query: 236 DSREPDAGRIHAGSKTAK 253
+A R+ A ++ AK
Sbjct: 1765 RELAEEAARLRALAEEAK 1782
Score = 35.8 bits (81), Expect = 0.053
Identities = 69/333 (20%), Positives = 133/333 (39%), Gaps = 44/333 (13%)
Query: 13 EKEVVLLRRSMAEGE--RARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQH 70
E E VL + A GE R + +++ + E +LRR A + L E Q
Sbjct: 1798 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL-----EEQA 1852
Query: 71 AQR--NVGERSPDQSEHTDGHTSVQS-VIEKLQEENRLLKQKVTHVE-----------DL 116
AQ ++ ER + +D Q ++E + R +++++ ++ +L
Sbjct: 1853 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1912
Query: 117 NAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ R ++ ++ +R + L+ + +L +E R R+ EE++ ++E A
Sbjct: 1913 ELELGRIRSNAEDTLRS--KEQAELEAARQRQLAAEE-ERRRREAEERVQKSLAAEEEAA 1969
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERAD----------RERAQSRIQELEEKVAS 226
R AALE V+ L+ ++ + + ERA+ +E AQ R+Q E+ A
Sbjct: 1970 RQ---RKAALEEVERLKAKVEEARR--LRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2024
Query: 227 LLHQ----VSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAE 282
+ Q + + ++ ++ A+ A +A E V R S++ AE
Sbjct: 2025 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE-REAAQSRRQVEEAE 2083
Query: 283 GGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLR 315
A ++ Q Q + E +E R
Sbjct: 2084 RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2116
Score = 35.0 bits (79), Expect = 0.090
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 32/230 (13%)
Query: 9 QHEREKEVVLLRRSMAEGERARA-ASDVLCRSLANETHQLRRT---------LTATAHMC 58
+ + E E R+ AE ER R A + + +SLA E R+ L A
Sbjct: 1930 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 1989
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNA 118
+ L + ++ Q + + + + + +V +K QE + L+Q+ + ++ L
Sbjct: 1990 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2049
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEIS---RLNRQLEEKINDCA------ 169
+ + + +E A+ +Q E R+++ RL + EE+ A
Sbjct: 2050 EAEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA 2103
Query: 170 -----EVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQ 214
E +QE A A AAL + Q + ++ +K +E+ R++AQ
Sbjct: 2104 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK--FAEQTLRQKAQ 2151
Score = 32.7 bits (73), Expect = 0.44
Identities = 46/254 (18%), Positives = 104/254 (40%), Gaps = 11/254 (4%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLAN-ETHQLRRTLTATAHMCQH 60
++ L++ Q E+E + + E +R A + ++ A E +L++ + +
Sbjct: 1315 EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1374
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAK- 119
A + Q +R++ E + ++ ++ + E +RL ++ V L +
Sbjct: 1375 AAV---DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1431
Query: 120 WQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASR 179
+R + ++ L A R + + ++E RL RQ++++ + + ELA+
Sbjct: 1432 TERQRGGAEGELQALRA--RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1489
Query: 180 TARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSRE 239
A A Q Q + + +E A+R Q+ ++ + +L + + R E
Sbjct: 1490 KAEAEAAREKQRALQALEELR--LQAEEAERRLRQAEVERARQVQVAL--ETAQRSAEAE 1545
Query: 240 PDAGRIHAGSKTAK 253
+ R KTA+
Sbjct: 1546 LQSKRASFAEKTAQ 1559
Score = 32.3 bits (72), Expect = 0.58
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 26/244 (10%)
Query: 7 QPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLD 66
Q Q E E L+ +AE RA+A ++ + + ++ L T Q L
Sbjct: 2341 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT-LV 2399
Query: 67 ERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW--QRYN 124
+ QR + D + ++ EKLQ+E +LL+ K ++ + + Q
Sbjct: 2400 QTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2457
Query: 125 ASRDEYVRGLHAQLRGLQIPHEP-----ELMRKEISRLNRQLEEKINDCAEVKQE----L 175
A + ++ + L+ + + +L + E+++ + EE+ +++QE +
Sbjct: 2458 ALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLV 2517
Query: 176 AASRTAR----------DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
A+ AR E +Q LEQQ +++ ++E R R Q ++ E E+ A
Sbjct: 2518 ASMEEARRRQHEAEEGVRRKQEELQQLEQQ-RRQQEELLAEENQRLREQLQLLE-EQHRA 2575
Query: 226 SLLH 229
+L H
Sbjct: 2576 ALAH 2579
Score = 29.3 bits (64), Expect = 4.9
Identities = 72/355 (20%), Positives = 119/355 (33%), Gaps = 52/355 (14%)
Query: 5 LSQPQHEREKEVVLLRRSMAE----GERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
L Q ER+ EV R +A+ + A +DV R L QL R L
Sbjct: 1131 LQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQREL----EQLGRQLRYYRESADP 1186
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVI--------EKLQEENRLLKQKVTH 112
L L + + Q + S+ + + EK++E R KQ +
Sbjct: 1187 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1246
Query: 113 VEDLNAKWQRYNASRD--------------------EYV--RGLHAQLRGLQ------IP 144
++D + Y A + EYV R +++L L I
Sbjct: 1247 IKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFIS 1306
Query: 145 HEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFM 204
M +E +Q E+ AEV+ L R +A + E++ +
Sbjct: 1307 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1366
Query: 205 SERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMV 264
E RE A Q+ + + L Q+ R+ I A ++ A+ AA+ L +
Sbjct: 1367 EEVVRREEAAVDAQQQKRSIQEELQQL------RQSSEAEIQAKARQAE--AAERSRLRI 1418
Query: 265 PGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAE 319
R + GG G Q + + + + E+ E L R V +
Sbjct: 1419 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1473
Score = 28.5 bits (62), Expect = 8.4
Identities = 38/218 (17%), Positives = 85/218 (38%), Gaps = 14/218 (6%)
Query: 5 LSQPQHER---EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
L + H++ ++E+ L+ E R R+ + S+ + +L + ++
Sbjct: 2163 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE--AENR 2220
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A L ++ + QR + E + + + + ++ +L ++ + L K
Sbjct: 2221 ALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKML 2280
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA 181
+ + L A+ LQ + EL +++ RL E+ + Q+LA
Sbjct: 2281 KEKMQAVQEATRLKAEAELLQ--QQKELAQEQARRLQEDKEQ-------MAQQLAEETQG 2331
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQE 219
LE + + ++ A + A+ RAQ+R +E
Sbjct: 2332 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2369
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 34/272 (12%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDV--LCRSLANETHQLRRTLTATAHMC 58
MQ + + + E E++ ++ +A+ + R D + + LA ET +RTL A
Sbjct: 2453 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAER--- 2509
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDG----HTSVQSVIEKLQEENRLLKQKVTHVE 114
Q + E + + V E S Q+ + + + EKL ++KVT V+
Sbjct: 2510 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ 2569
Query: 115 DLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQE 174
L + Q Q H+ E +R+ I+ L R+ E+ + ++ +
Sbjct: 2570 TLEIQRQ--------------------QSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2609
Query: 175 LAASRTAR-DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE----KVASLLH 229
+T + + L+ Q L+Q L+ KD + E+ ++++++L + K L
Sbjct: 2610 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLRE 2669
Query: 230 QVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
+ +Q E + R+ A + A+ +A E
Sbjct: 2670 EQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2701
Score = 38.1 bits (87), Expect = 0.011
Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 11/258 (4%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEG----ERARAASDVLCRSLANETHQLRRTLTATAH 56
+Q L Q E E+ R S AE ER+ V L E + R A A
Sbjct: 1700 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER-RAQQQAEAE 1758
Query: 57 MCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSV-QSVIEKLQEENRLLKQKVTHVED 115
+ A+ ER + N R Q+E S+ Q+ EK +EE ++ E+
Sbjct: 1759 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1818
Query: 116 LNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+ + E R L ++ E EL+R L + E+ +++EL
Sbjct: 1819 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR-----LRAETEQGEQQRQLLEEEL 1873
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQ 235
A + AA ++ Q LE ++ + + A + RA+ + EK L + R
Sbjct: 1874 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1933
Query: 236 DSREPDAGRIHAGSKTAK 253
+A R+ A ++ AK
Sbjct: 1934 RELAEEAARLRALAEEAK 1951
Score = 35.8 bits (81), Expect = 0.053
Identities = 69/333 (20%), Positives = 133/333 (39%), Gaps = 44/333 (13%)
Query: 13 EKEVVLLRRSMAEGE--RARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQH 70
E E VL + A GE R + +++ + E +LRR A + L E Q
Sbjct: 1967 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL-----EEQA 2021
Query: 71 AQR--NVGERSPDQSEHTDGHTSVQS-VIEKLQEENRLLKQKVTHVE-----------DL 116
AQ ++ ER + +D Q ++E + R +++++ ++ +L
Sbjct: 2022 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 2081
Query: 117 NAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ R ++ ++ +R + L+ + +L +E R R+ EE++ ++E A
Sbjct: 2082 ELELGRIRSNAEDTLRS--KEQAELEAARQRQLAAEE-ERRRREAEERVQKSLAAEEEAA 2138
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERAD----------RERAQSRIQELEEKVAS 226
R AALE V+ L+ ++ + + ERA+ +E AQ R+Q E+ A
Sbjct: 2139 RQ---RKAALEEVERLKAKVEEARR--LRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2193
Query: 227 LLHQ----VSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAE 282
+ Q + + ++ ++ A+ A +A E V R S++ AE
Sbjct: 2194 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE-REAAQSRRQVEEAE 2252
Query: 283 GGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLR 315
A ++ Q Q + E +E R
Sbjct: 2253 RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2285
Score = 35.0 bits (79), Expect = 0.090
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 32/230 (13%)
Query: 9 QHEREKEVVLLRRSMAEGERARA-ASDVLCRSLANETHQLRRT---------LTATAHMC 58
+ + E E R+ AE ER R A + + +SLA E R+ L A
Sbjct: 2099 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 2158
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNA 118
+ L + ++ Q + + + + + +V +K QE + L+Q+ + ++ L
Sbjct: 2159 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2218
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEIS---RLNRQLEEKINDCA------ 169
+ + + +E A+ +Q E R+++ RL + EE+ A
Sbjct: 2219 EAEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA 2272
Query: 170 -----EVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQ 214
E +QE A A AAL + Q + ++ +K +E+ R++AQ
Sbjct: 2273 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK--FAEQTLRQKAQ 2320
Score = 32.7 bits (73), Expect = 0.44
Identities = 46/254 (18%), Positives = 104/254 (40%), Gaps = 11/254 (4%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLAN-ETHQLRRTLTATAHMCQH 60
++ L++ Q E+E + + E +R A + ++ A E +L++ + +
Sbjct: 1484 EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1543
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAK- 119
A + Q +R++ E + ++ ++ + E +RL ++ V L +
Sbjct: 1544 AAV---DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1600
Query: 120 WQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASR 179
+R + ++ L A R + + ++E RL RQ++++ + + ELA+
Sbjct: 1601 TERQRGGAEGELQALRA--RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1658
Query: 180 TARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSRE 239
A A Q Q + + +E A+R Q+ ++ + +L + + R E
Sbjct: 1659 KAEAEAAREKQRALQALEELR--LQAEEAERRLRQAEVERARQVQVAL--ETAQRSAEAE 1714
Query: 240 PDAGRIHAGSKTAK 253
+ R KTA+
Sbjct: 1715 LQSKRASFAEKTAQ 1728
Score = 32.3 bits (72), Expect = 0.58
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 26/244 (10%)
Query: 7 QPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLD 66
Q Q E E L+ +AE RA+A ++ + + ++ L T Q L
Sbjct: 2510 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT-LV 2568
Query: 67 ERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW--QRYN 124
+ QR + D + ++ EKLQ+E +LL+ K ++ + + Q
Sbjct: 2569 QTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2626
Query: 125 ASRDEYVRGLHAQLRGLQIPHEP-----ELMRKEISRLNRQLEEKINDCAEVKQE----L 175
A + ++ + L+ + + +L + E+++ + EE+ +++QE +
Sbjct: 2627 ALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLV 2686
Query: 176 AASRTAR----------DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
A+ AR E +Q LEQQ +++ ++E R R Q ++ E E+ A
Sbjct: 2687 ASMEEARRRQHEAEEGVRRKQEELQQLEQQ-RRQQEELLAEENQRLREQLQLLE-EQHRA 2744
Query: 226 SLLH 229
+L H
Sbjct: 2745 ALAH 2748
Score = 29.3 bits (64), Expect = 4.9
Identities = 72/355 (20%), Positives = 119/355 (33%), Gaps = 52/355 (14%)
Query: 5 LSQPQHEREKEVVLLRRSMAE----GERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
L Q ER+ EV R +A+ + A +DV R L QL R L
Sbjct: 1300 LQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQREL----EQLGRQLRYYRESADP 1355
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVI--------EKLQEENRLLKQKVTH 112
L L + + Q + S+ + + EK++E R KQ +
Sbjct: 1356 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1415
Query: 113 VEDLNAKWQRYNASRD--------------------EYV--RGLHAQLRGLQ------IP 144
++D + Y A + EYV R +++L L I
Sbjct: 1416 IKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFIS 1475
Query: 145 HEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFM 204
M +E +Q E+ AEV+ L R +A + E++ +
Sbjct: 1476 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1535
Query: 205 SERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMV 264
E RE A Q+ + + L Q+ R+ I A ++ A+ AA+ L +
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQEELQQL------RQSSEAEIQAKARQAE--AAERSRLRI 1587
Query: 265 PGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAE 319
R + GG G Q + + + + E+ E L R V +
Sbjct: 1588 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1642
Score = 28.5 bits (62), Expect = 8.4
Identities = 38/218 (17%), Positives = 85/218 (38%), Gaps = 14/218 (6%)
Query: 5 LSQPQHER---EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
L + H++ ++E+ L+ E R R+ + S+ + +L + ++
Sbjct: 2332 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE--AENR 2389
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A L ++ + QR + E + + + + ++ +L ++ + L K
Sbjct: 2390 ALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKML 2449
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA 181
+ + L A+ LQ + EL +++ RL E+ + Q+LA
Sbjct: 2450 KEKMQAVQEATRLKAEAELLQ--QQKELAQEQARRLQEDKEQ-------MAQQLAEETQG 2500
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQE 219
LE + + ++ A + A+ RAQ+R +E
Sbjct: 2501 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2538
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 34/272 (12%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDV--LCRSLANETHQLRRTLTATAHMC 58
MQ + + + E E++ ++ +A+ + R D + + LA ET +RTL A
Sbjct: 2294 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAER--- 2350
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDG----HTSVQSVIEKLQEENRLLKQKVTHVE 114
Q + E + + V E S Q+ + + + EKL ++KVT V+
Sbjct: 2351 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ 2410
Query: 115 DLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQE 174
L + Q Q H+ E +R+ I+ L R+ E+ + ++ +
Sbjct: 2411 TLEIQRQ--------------------QSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2450
Query: 175 LAASRTAR-DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE----KVASLLH 229
+T + + L+ Q L+Q L+ KD + E+ ++++++L + K L
Sbjct: 2451 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLRE 2510
Query: 230 QVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
+ +Q E + R+ A + A+ +A E
Sbjct: 2511 EQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2542
Score = 38.1 bits (87), Expect = 0.011
Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 11/258 (4%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEG----ERARAASDVLCRSLANETHQLRRTLTATAH 56
+Q L Q E E+ R S AE ER+ V L E + R A A
Sbjct: 1541 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER-RAQQQAEAE 1599
Query: 57 MCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSV-QSVIEKLQEENRLLKQKVTHVED 115
+ A+ ER + N R Q+E S+ Q+ EK +EE ++ E+
Sbjct: 1600 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1659
Query: 116 LNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+ + E R L ++ E EL+R L + E+ +++EL
Sbjct: 1660 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR-----LRAETEQGEQQRQLLEEEL 1714
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQ 235
A + AA ++ Q LE ++ + + A + RA+ + EK L + R
Sbjct: 1715 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1774
Query: 236 DSREPDAGRIHAGSKTAK 253
+A R+ A ++ AK
Sbjct: 1775 RELAEEAARLRALAEEAK 1792
Score = 35.8 bits (81), Expect = 0.053
Identities = 69/333 (20%), Positives = 133/333 (39%), Gaps = 44/333 (13%)
Query: 13 EKEVVLLRRSMAEGE--RARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQH 70
E E VL + A GE R + +++ + E +LRR A + L E Q
Sbjct: 1808 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL-----EEQA 1862
Query: 71 AQR--NVGERSPDQSEHTDGHTSVQS-VIEKLQEENRLLKQKVTHVE-----------DL 116
AQ ++ ER + +D Q ++E + R +++++ ++ +L
Sbjct: 1863 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1922
Query: 117 NAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ R ++ ++ +R + L+ + +L +E R R+ EE++ ++E A
Sbjct: 1923 ELELGRIRSNAEDTLRS--KEQAELEAARQRQLAAEE-ERRRREAEERVQKSLAAEEEAA 1979
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERAD----------RERAQSRIQELEEKVAS 226
R AALE V+ L+ ++ + + ERA+ +E AQ R+Q E+ A
Sbjct: 1980 RQ---RKAALEEVERLKAKVEEARR--LRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2034
Query: 227 LLHQ----VSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAE 282
+ Q + + ++ ++ A+ A +A E V R S++ AE
Sbjct: 2035 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE-REAAQSRRQVEEAE 2093
Query: 283 GGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLR 315
A ++ Q Q + E +E R
Sbjct: 2094 RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2126
Score = 35.0 bits (79), Expect = 0.090
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 32/230 (13%)
Query: 9 QHEREKEVVLLRRSMAEGERARA-ASDVLCRSLANETHQLRRT---------LTATAHMC 58
+ + E E R+ AE ER R A + + +SLA E R+ L A
Sbjct: 1940 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 1999
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNA 118
+ L + ++ Q + + + + + +V +K QE + L+Q+ + ++ L
Sbjct: 2000 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2059
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEIS---RLNRQLEEKINDCA------ 169
+ + + +E A+ +Q E R+++ RL + EE+ A
Sbjct: 2060 EAEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA 2113
Query: 170 -----EVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQ 214
E +QE A A AAL + Q + ++ +K +E+ R++AQ
Sbjct: 2114 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK--FAEQTLRQKAQ 2161
Score = 32.7 bits (73), Expect = 0.44
Identities = 46/254 (18%), Positives = 104/254 (40%), Gaps = 11/254 (4%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLAN-ETHQLRRTLTATAHMCQH 60
++ L++ Q E+E + + E +R A + ++ A E +L++ + +
Sbjct: 1325 EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1384
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAK- 119
A + Q +R++ E + ++ ++ + E +RL ++ V L +
Sbjct: 1385 AAV---DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1441
Query: 120 WQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASR 179
+R + ++ L A R + + ++E RL RQ++++ + + ELA+
Sbjct: 1442 TERQRGGAEGELQALRA--RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1499
Query: 180 TARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSRE 239
A A Q Q + + +E A+R Q+ ++ + +L + + R E
Sbjct: 1500 KAEAEAAREKQRALQALEELR--LQAEEAERRLRQAEVERARQVQVAL--ETAQRSAEAE 1555
Query: 240 PDAGRIHAGSKTAK 253
+ R KTA+
Sbjct: 1556 LQSKRASFAEKTAQ 1569
Score = 32.3 bits (72), Expect = 0.58
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 26/244 (10%)
Query: 7 QPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLD 66
Q Q E E L+ +AE RA+A ++ + + ++ L T Q L
Sbjct: 2351 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT-LV 2409
Query: 67 ERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW--QRYN 124
+ QR + D + ++ EKLQ+E +LL+ K ++ + + Q
Sbjct: 2410 QTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2467
Query: 125 ASRDEYVRGLHAQLRGLQIPHEP-----ELMRKEISRLNRQLEEKINDCAEVKQE----L 175
A + ++ + L+ + + +L + E+++ + EE+ +++QE +
Sbjct: 2468 ALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLV 2527
Query: 176 AASRTAR----------DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
A+ AR E +Q LEQQ +++ ++E R R Q ++ E E+ A
Sbjct: 2528 ASMEEARRRQHEAEEGVRRKQEELQQLEQQ-RRQQEELLAEENQRLREQLQLLE-EQHRA 2585
Query: 226 SLLH 229
+L H
Sbjct: 2586 ALAH 2589
Score = 29.3 bits (64), Expect = 4.9
Identities = 72/355 (20%), Positives = 119/355 (33%), Gaps = 52/355 (14%)
Query: 5 LSQPQHEREKEVVLLRRSMAE----GERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
L Q ER+ EV R +A+ + A +DV R L QL R L
Sbjct: 1141 LQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQREL----EQLGRQLRYYRESADP 1196
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVI--------EKLQEENRLLKQKVTH 112
L L + + Q + S+ + + EK++E R KQ +
Sbjct: 1197 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1256
Query: 113 VEDLNAKWQRYNASRD--------------------EYV--RGLHAQLRGLQ------IP 144
++D + Y A + EYV R +++L L I
Sbjct: 1257 IKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFIS 1316
Query: 145 HEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFM 204
M +E +Q E+ AEV+ L R +A + E++ +
Sbjct: 1317 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1376
Query: 205 SERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMV 264
E RE A Q+ + + L Q+ R+ I A ++ A+ AA+ L +
Sbjct: 1377 EEVVRREEAAVDAQQQKRSIQEELQQL------RQSSEAEIQAKARQAE--AAERSRLRI 1428
Query: 265 PGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAE 319
R + GG G Q + + + + E+ E L R V +
Sbjct: 1429 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1483
Score = 28.5 bits (62), Expect = 8.4
Identities = 38/218 (17%), Positives = 85/218 (38%), Gaps = 14/218 (6%)
Query: 5 LSQPQHER---EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
L + H++ ++E+ L+ E R R+ + S+ + +L + ++
Sbjct: 2173 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE--AENR 2230
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A L ++ + QR + E + + + + ++ +L ++ + L K
Sbjct: 2231 ALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKML 2290
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA 181
+ + L A+ LQ + EL +++ RL E+ + Q+LA
Sbjct: 2291 KEKMQAVQEATRLKAEAELLQ--QQKELAQEQARRLQEDKEQ-------MAQQLAEETQG 2341
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQE 219
LE + + ++ A + A+ RAQ+R +E
Sbjct: 2342 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2379
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 34/272 (12%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDV--LCRSLANETHQLRRTLTATAHMC 58
MQ + + + E E++ ++ +A+ + R D + + LA ET +RTL A
Sbjct: 2302 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAER--- 2358
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDG----HTSVQSVIEKLQEENRLLKQKVTHVE 114
Q + E + + V E S Q+ + + + EKL ++KVT V+
Sbjct: 2359 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ 2418
Query: 115 DLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQE 174
L + Q Q H+ E +R+ I+ L R+ E+ + ++ +
Sbjct: 2419 TLEIQRQ--------------------QSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2458
Query: 175 LAASRTAR-DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE----KVASLLH 229
+T + + L+ Q L+Q L+ KD + E+ ++++++L + K L
Sbjct: 2459 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLRE 2518
Query: 230 QVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
+ +Q E + R+ A + A+ +A E
Sbjct: 2519 EQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2550
Score = 38.1 bits (87), Expect = 0.011
Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 11/258 (4%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEG----ERARAASDVLCRSLANETHQLRRTLTATAH 56
+Q L Q E E+ R S AE ER+ V L E + R A A
Sbjct: 1549 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER-RAQQQAEAE 1607
Query: 57 MCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSV-QSVIEKLQEENRLLKQKVTHVED 115
+ A+ ER + N R Q+E S+ Q+ EK +EE ++ E+
Sbjct: 1608 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1667
Query: 116 LNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+ + E R L ++ E EL+R L + E+ +++EL
Sbjct: 1668 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR-----LRAETEQGEQQRQLLEEEL 1722
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQ 235
A + AA ++ Q LE ++ + + A + RA+ + EK L + R
Sbjct: 1723 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1782
Query: 236 DSREPDAGRIHAGSKTAK 253
+A R+ A ++ AK
Sbjct: 1783 RELAEEAARLRALAEEAK 1800
Score = 35.8 bits (81), Expect = 0.053
Identities = 69/333 (20%), Positives = 133/333 (39%), Gaps = 44/333 (13%)
Query: 13 EKEVVLLRRSMAEGE--RARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQH 70
E E VL + A GE R + +++ + E +LRR A + L E Q
Sbjct: 1816 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL-----EEQA 1870
Query: 71 AQR--NVGERSPDQSEHTDGHTSVQS-VIEKLQEENRLLKQKVTHVE-----------DL 116
AQ ++ ER + +D Q ++E + R +++++ ++ +L
Sbjct: 1871 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1930
Query: 117 NAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ R ++ ++ +R + L+ + +L +E R R+ EE++ ++E A
Sbjct: 1931 ELELGRIRSNAEDTLRS--KEQAELEAARQRQLAAEE-ERRRREAEERVQKSLAAEEEAA 1987
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERAD----------RERAQSRIQELEEKVAS 226
R AALE V+ L+ ++ + + ERA+ +E AQ R+Q E+ A
Sbjct: 1988 RQ---RKAALEEVERLKAKVEEARR--LRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2042
Query: 227 LLHQ----VSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAE 282
+ Q + + ++ ++ A+ A +A E V R S++ AE
Sbjct: 2043 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE-REAAQSRRQVEEAE 2101
Query: 283 GGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLR 315
A ++ Q Q + E +E R
Sbjct: 2102 RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2134
Score = 35.0 bits (79), Expect = 0.090
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 32/230 (13%)
Query: 9 QHEREKEVVLLRRSMAEGERARA-ASDVLCRSLANETHQLRRT---------LTATAHMC 58
+ + E E R+ AE ER R A + + +SLA E R+ L A
Sbjct: 1948 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 2007
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNA 118
+ L + ++ Q + + + + + +V +K QE + L+Q+ + ++ L
Sbjct: 2008 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2067
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEIS---RLNRQLEEKINDCA------ 169
+ + + +E A+ +Q E R+++ RL + EE+ A
Sbjct: 2068 EAEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA 2121
Query: 170 -----EVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQ 214
E +QE A A AAL + Q + ++ +K +E+ R++AQ
Sbjct: 2122 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK--FAEQTLRQKAQ 2169
Score = 32.7 bits (73), Expect = 0.44
Identities = 46/254 (18%), Positives = 104/254 (40%), Gaps = 11/254 (4%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLAN-ETHQLRRTLTATAHMCQH 60
++ L++ Q E+E + + E +R A + ++ A E +L++ + +
Sbjct: 1333 EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1392
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAK- 119
A + Q +R++ E + ++ ++ + E +RL ++ V L +
Sbjct: 1393 AAV---DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1449
Query: 120 WQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASR 179
+R + ++ L A R + + ++E RL RQ++++ + + ELA+
Sbjct: 1450 TERQRGGAEGELQALRA--RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1507
Query: 180 TARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSRE 239
A A Q Q + + +E A+R Q+ ++ + +L + + R E
Sbjct: 1508 KAEAEAAREKQRALQALEELR--LQAEEAERRLRQAEVERARQVQVAL--ETAQRSAEAE 1563
Query: 240 PDAGRIHAGSKTAK 253
+ R KTA+
Sbjct: 1564 LQSKRASFAEKTAQ 1577
Score = 32.3 bits (72), Expect = 0.58
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 26/244 (10%)
Query: 7 QPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLD 66
Q Q E E L+ +AE RA+A ++ + + ++ L T Q L
Sbjct: 2359 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT-LV 2417
Query: 67 ERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW--QRYN 124
+ QR + D + ++ EKLQ+E +LL+ K ++ + + Q
Sbjct: 2418 QTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2475
Query: 125 ASRDEYVRGLHAQLRGLQIPHEP-----ELMRKEISRLNRQLEEKINDCAEVKQE----L 175
A + ++ + L+ + + +L + E+++ + EE+ +++QE +
Sbjct: 2476 ALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLV 2535
Query: 176 AASRTAR----------DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
A+ AR E +Q LEQQ +++ ++E R R Q ++ E E+ A
Sbjct: 2536 ASMEEARRRQHEAEEGVRRKQEELQQLEQQ-RRQQEELLAEENQRLREQLQLLE-EQHRA 2593
Query: 226 SLLH 229
+L H
Sbjct: 2594 ALAH 2597
Score = 29.3 bits (64), Expect = 4.9
Identities = 72/355 (20%), Positives = 119/355 (33%), Gaps = 52/355 (14%)
Query: 5 LSQPQHEREKEVVLLRRSMAE----GERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
L Q ER+ EV R +A+ + A +DV R L QL R L
Sbjct: 1149 LQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQREL----EQLGRQLRYYRESADP 1204
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVI--------EKLQEENRLLKQKVTH 112
L L + + Q + S+ + + EK++E R KQ +
Sbjct: 1205 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1264
Query: 113 VEDLNAKWQRYNASRD--------------------EYV--RGLHAQLRGLQ------IP 144
++D + Y A + EYV R +++L L I
Sbjct: 1265 IKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFIS 1324
Query: 145 HEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFM 204
M +E +Q E+ AEV+ L R +A + E++ +
Sbjct: 1325 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1384
Query: 205 SERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMV 264
E RE A Q+ + + L Q+ R+ I A ++ A+ AA+ L +
Sbjct: 1385 EEVVRREEAAVDAQQQKRSIQEELQQL------RQSSEAEIQAKARQAE--AAERSRLRI 1436
Query: 265 PGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAE 319
R + GG G Q + + + + E+ E L R V +
Sbjct: 1437 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1491
Score = 28.5 bits (62), Expect = 8.4
Identities = 38/218 (17%), Positives = 85/218 (38%), Gaps = 14/218 (6%)
Query: 5 LSQPQHER---EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
L + H++ ++E+ L+ E R R+ + S+ + +L + ++
Sbjct: 2181 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE--AENR 2238
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A L ++ + QR + E + + + + ++ +L ++ + L K
Sbjct: 2239 ALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKML 2298
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA 181
+ + L A+ LQ + EL +++ RL E+ + Q+LA
Sbjct: 2299 KEKMQAVQEATRLKAEAELLQ--QQKELAQEQARRLQEDKEQ-------MAQQLAEETQG 2349
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQE 219
LE + + ++ A + A+ RAQ+R +E
Sbjct: 2350 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2387
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 34/272 (12%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEGERARAASDV--LCRSLANETHQLRRTLTATAHMC 58
MQ + + + E E++ ++ +A+ + R D + + LA ET +RTL A
Sbjct: 2343 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAER--- 2399
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDG----HTSVQSVIEKLQEENRLLKQKVTHVE 114
Q + E + + V E S Q+ + + + EKL ++KVT V+
Sbjct: 2400 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQ 2459
Query: 115 DLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQE 174
L + Q Q H+ E +R+ I+ L R+ E+ + ++ +
Sbjct: 2460 TLEIQRQ--------------------QSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2499
Query: 175 LAASRTAR-DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE----KVASLLH 229
+T + + L+ Q L+Q L+ KD + E+ ++++++L + K L
Sbjct: 2500 SEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLRE 2559
Query: 230 QVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
+ +Q E + R+ A + A+ +A E
Sbjct: 2560 EQQRQQQQMEQERQRLVASMEEARRRQHEAEE 2591
Score = 38.1 bits (87), Expect = 0.011
Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 11/258 (4%)
Query: 1 MQQLLSQPQHEREKEVVLLRRSMAEG----ERARAASDVLCRSLANETHQLRRTLTATAH 56
+Q L Q E E+ R S AE ER+ V L E + R A A
Sbjct: 1590 VQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAER-RAQQQAEAE 1648
Query: 57 MCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSV-QSVIEKLQEENRLLKQKVTHVED 115
+ A+ ER + N R Q+E S+ Q+ EK +EE ++ E+
Sbjct: 1649 RAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1708
Query: 116 LNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+ + E R L ++ E EL+R L + E+ +++EL
Sbjct: 1709 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR-----LRAETEQGEQQRQLLEEEL 1763
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQ 235
A + AA ++ Q LE ++ + + A + RA+ + EK L + R
Sbjct: 1764 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1823
Query: 236 DSREPDAGRIHAGSKTAK 253
+A R+ A ++ AK
Sbjct: 1824 RELAEEAARLRALAEEAK 1841
Score = 35.8 bits (81), Expect = 0.053
Identities = 69/333 (20%), Positives = 133/333 (39%), Gaps = 44/333 (13%)
Query: 13 EKEVVLLRRSMAEGE--RARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQH 70
E E VL + A GE R + +++ + E +LRR A + L E Q
Sbjct: 1857 EAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL-----EEQA 1911
Query: 71 AQR--NVGERSPDQSEHTDGHTSVQS-VIEKLQEENRLLKQKVTHVE-----------DL 116
AQ ++ ER + +D Q ++E + R +++++ ++ +L
Sbjct: 1912 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1971
Query: 117 NAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA 176
+ R ++ ++ +R + L+ + +L +E R R+ EE++ ++E A
Sbjct: 1972 ELELGRIRSNAEDTLRS--KEQAELEAARQRQLAAEE-ERRRREAEERVQKSLAAEEEAA 2028
Query: 177 ASRTARDAALERVQMLEQQILAYKDDFMSERAD----------RERAQSRIQELEEKVAS 226
R AALE V+ L+ ++ + + ERA+ +E AQ R+Q E+ A
Sbjct: 2029 RQ---RKAALEEVERLKAKVEEARR--LRERAEQESARQLQLAQEAAQKRLQAEEKAHAF 2083
Query: 227 LLHQ----VSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAE 282
+ Q + + ++ ++ A+ A +A E V R S++ AE
Sbjct: 2084 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE-REAAQSRRQVEEAE 2142
Query: 283 GGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLR 315
A ++ Q Q + E +E R
Sbjct: 2143 RLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2175
Score = 35.0 bits (79), Expect = 0.090
Identities = 49/230 (21%), Positives = 94/230 (40%), Gaps = 32/230 (13%)
Query: 9 QHEREKEVVLLRRSMAEGERARA-ASDVLCRSLANETHQLRRT---------LTATAHMC 58
+ + E E R+ AE ER R A + + +SLA E R+ L A
Sbjct: 1989 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 2048
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNA 118
+ L + ++ Q + + + + + +V +K QE + L+Q+ + ++ L
Sbjct: 2049 RRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG 2108
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEIS---RLNRQLEEKINDCA------ 169
+ + + +E A+ +Q E R+++ RL + EE+ A
Sbjct: 2109 EAEAARRAAEE------AEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA 2162
Query: 170 -----EVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQ 214
E +QE A A AAL + Q + ++ +K +E+ R++AQ
Sbjct: 2163 EKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK--FAEQTLRQKAQ 2210
Score = 32.7 bits (73), Expect = 0.44
Identities = 46/254 (18%), Positives = 104/254 (40%), Gaps = 11/254 (4%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLAN-ETHQLRRTLTATAHMCQH 60
++ L++ Q E+E + + E +R A + ++ A E +L++ + +
Sbjct: 1374 EERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1433
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAK- 119
A + Q +R++ E + ++ ++ + E +RL ++ V L +
Sbjct: 1434 AAV---DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1490
Query: 120 WQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASR 179
+R + ++ L A R + + ++E RL RQ++++ + + ELA+
Sbjct: 1491 TERQRGGAEGELQALRA--RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1548
Query: 180 TARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSRE 239
A A Q Q + + +E A+R Q+ ++ + +L + + R E
Sbjct: 1549 KAEAEAAREKQRALQALEELR--LQAEEAERRLRQAEVERARQVQVAL--ETAQRSAEAE 1604
Query: 240 PDAGRIHAGSKTAK 253
+ R KTA+
Sbjct: 1605 LQSKRASFAEKTAQ 1618
Score = 32.3 bits (72), Expect = 0.58
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 26/244 (10%)
Query: 7 QPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLD 66
Q Q E E L+ +AE RA+A ++ + + ++ L T Q L
Sbjct: 2400 QRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVT-LV 2458
Query: 67 ERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW--QRYN 124
+ QR + D + ++ EKLQ+E +LL+ K ++ + + Q
Sbjct: 2459 QTLEIQRQQSDH--DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2516
Query: 125 ASRDEYVRGLHAQLRGLQIPHEP-----ELMRKEISRLNRQLEEKINDCAEVKQE----L 175
A + ++ + L+ + + +L + E+++ + EE+ +++QE +
Sbjct: 2517 ALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLV 2576
Query: 176 AASRTAR----------DAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
A+ AR E +Q LEQQ +++ ++E R R Q ++ E E+ A
Sbjct: 2577 ASMEEARRRQHEAEEGVRRKQEELQQLEQQ-RRQQEELLAEENQRLREQLQLLE-EQHRA 2634
Query: 226 SLLH 229
+L H
Sbjct: 2635 ALAH 2638
Score = 29.3 bits (64), Expect = 4.9
Identities = 72/355 (20%), Positives = 119/355 (33%), Gaps = 52/355 (14%)
Query: 5 LSQPQHEREKEVVLLRRSMAE----GERARAASDVLCRSLANETHQLRRTLTATAHMCQH 60
L Q ER+ EV R +A+ + A +DV R L QL R L
Sbjct: 1190 LQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQREL----EQLGRQLRYYRESADP 1245
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVI--------EKLQEENRLLKQKVTH 112
L L + + Q + S+ + + EK++E R KQ +
Sbjct: 1246 LGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINA 1305
Query: 113 VEDLNAKWQRYNASRD--------------------EYV--RGLHAQLRGLQ------IP 144
++D + Y A + EYV R +++L L I
Sbjct: 1306 IKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFIS 1365
Query: 145 HEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFM 204
M +E +Q E+ AEV+ L R +A + E++ +
Sbjct: 1366 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1425
Query: 205 SERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMV 264
E RE A Q+ + + L Q+ R+ I A ++ A+ AA+ L +
Sbjct: 1426 EEVVRREEAAVDAQQQKRSIQEELQQL------RQSSEAEIQAKARQAE--AAERSRLRI 1477
Query: 265 PGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAE 319
R + GG G Q + + + + E+ E L R V +
Sbjct: 1478 EEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1532
Score = 28.5 bits (62), Expect = 8.4
Identities = 38/218 (17%), Positives = 85/218 (38%), Gaps = 14/218 (6%)
Query: 5 LSQPQHER---EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
L + H++ ++E+ L+ E R R+ + S+ + +L + ++
Sbjct: 2222 LEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIE--AENR 2279
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A L ++ + QR + E + + + + ++ +L ++ + L K
Sbjct: 2280 ALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKML 2339
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA 181
+ + L A+ LQ + EL +++ RL E+ + Q+LA
Sbjct: 2340 KEKMQAVQEATRLKAEAELLQ--QQKELAQEQARRLQEDKEQ-------MAQQLAEETQG 2390
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQE 219
LE + + ++ A + A+ RAQ+R +E
Sbjct: 2391 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2428
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 49.3 bits (116), Expect = 5e-06
Identities = 54/241 (22%), Positives = 101/241 (41%), Gaps = 35/241 (14%)
Query: 5 LSQPQHEREKEVVLLRRSMAE--GERARAASDVLCRSLANETHQLRRTLTATAHMCQHLA 62
LS+ E+E+ ++ L R+ AE GE+A A +L ++ N+ + R L+ + + LA
Sbjct: 493 LSRLNREQEERLLELERA-AELWGEQAEARRQIL-ETMQNDRTTISRALSQNRELKEQLA 550
Query: 63 K-----------------CLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRL 105
+ L QH +R +G++ + + EKL E
Sbjct: 551 ELQSGFVKLTNENMEITSALQSEQHVKRELGKK-------------LGELQEKLSELKET 597
Query: 106 LKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKI 165
++ K + L + +Y +YV ++ H L++ ++ +Q E +
Sbjct: 598 VELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQEAQG 657
Query: 166 NDCAEV-KQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKV 224
AE+ +QEL ++ +AA ++ Q L Q+ + DRE + +E EE V
Sbjct: 658 KAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEEEEEEEAV 717
Query: 225 A 225
A
Sbjct: 718 A 718
Score = 43.1 bits (100), Expect = 3e-04
Identities = 56/252 (22%), Positives = 109/252 (43%), Gaps = 34/252 (13%)
Query: 40 LANETHQLRRTLTATAHMCQHL---AKCLDER-QHAQRNVGERSPDQSEHTDGHTSVQSV 95
L +E +L+ L T H + ++ L R Q+++R VGE S +
Sbjct: 226 LVSEKAELQTALAHTQHAARQKEGESEDLASRLQYSRRRVGELERALSAVSTQQKKADRY 285
Query: 96 IEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEIS 155
++L +E L+ ++ N ++ + +E +R L + G+Q+ E + E++
Sbjct: 286 NKELTKERDALRLELYKNTQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMT 345
Query: 156 RL--------------NRQLEEKINDCAEVKQELA-ASRTARDAALERVQMLE------- 193
L N+QL++ + + A+++ L + R +ER + E
Sbjct: 346 ELLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESA 405
Query: 194 ---QQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSK 250
Q++ + + R ++E + SR+QELE +A L +Q++ EP AG S+
Sbjct: 406 MWRQRMQQMSEQVHTLREEKECSMSRVQELETSLAELRNQMA-EPPPPEPPAG----PSE 460
Query: 251 TAKYLAADALEL 262
+ L A+A L
Sbjct: 461 VEQQLQAEAEHL 472
Score = 31.6 bits (70), Expect = 0.99
Identities = 45/193 (23%), Positives = 81/193 (41%), Gaps = 15/193 (7%)
Query: 46 QLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPD-QSEHTDGHTSVQSVIEK---LQE 101
QL++ + A + HL + ++ + Q + + + + E +Q + E+ L+E
Sbjct: 364 QLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMSEQVHTLRE 423
Query: 102 ENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQL 161
E +V +E A+ + A Q+ E E +RKE+ L QL
Sbjct: 424 EKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQL 483
Query: 162 EEKINDCAEVKQELAASRTARDAALERVQML-------EQQILAYKDDFMSERADRERAQ 214
+ ++ D E L + R LER L +QIL + ++R RA
Sbjct: 484 QAQVQD-NEGLSRLNREQEERLLELERAAELWGEQAEARRQIL---ETMQNDRTTISRAL 539
Query: 215 SRIQELEEKVASL 227
S+ +EL+E++A L
Sbjct: 540 SQNRELKEQLAEL 552
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 48.1 bits (113), Expect = 1e-05
Identities = 38/144 (26%), Positives = 69/144 (47%), Gaps = 13/144 (9%)
Query: 83 SEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQ 142
+E D +V + L+E+ +KQ+ + V+DL + QR N + ++ L AQ + Q
Sbjct: 340 NEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTN----LQKLQAQKQ--Q 393
Query: 143 IPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDD 202
+ + + ++ ++L QL+E CAE Q +++ + + E QI Y+++
Sbjct: 394 VQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKA-------ELTSQESQISTYEEE 446
Query: 203 FMSERADRERAQSRIQELEEKVAS 226
R + R Q ELEE V S
Sbjct: 447 LAKAREELSRLQQETAELEESVES 470
Score = 32.7 bits (73), Expect = 0.44
Identities = 18/80 (22%), Positives = 37/80 (46%)
Query: 152 KEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRE 211
KE+ LN ++ + + V+Q+L VQ L+ ++ + +A ++
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 392
Query: 212 RAQSRIQELEEKVASLLHQV 231
+ Q + EL+E+ A L Q+
Sbjct: 393 QVQELLDELDEQKAQLEEQL 412
>gi|192807309 TNFAIP3 interacting protein 3 [Homo sapiens]
Length = 325
Score = 47.8 bits (112), Expect = 1e-05
Identities = 41/167 (24%), Positives = 73/167 (43%), Gaps = 34/167 (20%)
Query: 60 HLAKCLDERQHAQRNVGERSPDQSEHTDGHTS-VQSVIEKLQEENRLLKQKVTHVEDLNA 118
H + D+RQ + + D+ + + + + +L+EEN+LLK K T
Sbjct: 94 HQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLA----- 148
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKIN-DCAEVKQELAA 177
N ++ Y EI RLN+ L++ +N C+ + L
Sbjct: 149 -----NKEKEHY--------------------ECEIKRLNKALQDALNIKCSFSEDCLRK 183
Query: 178 SRT--ARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE 222
SR + +++L+QQ+ Y++DF ER+DRER +EL++
Sbjct: 184 SRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQ 230
>gi|192807305 TNFAIP3 interacting protein 3 [Homo sapiens]
Length = 325
Score = 47.8 bits (112), Expect = 1e-05
Identities = 41/167 (24%), Positives = 73/167 (43%), Gaps = 34/167 (20%)
Query: 60 HLAKCLDERQHAQRNVGERSPDQSEHTDGHTS-VQSVIEKLQEENRLLKQKVTHVEDLNA 118
H + D+RQ + + D+ + + + + +L+EEN+LLK K T
Sbjct: 94 HQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLA----- 148
Query: 119 KWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKIN-DCAEVKQELAA 177
N ++ Y EI RLN+ L++ +N C+ + L
Sbjct: 149 -----NKEKEHY--------------------ECEIKRLNKALQDALNIKCSFSEDCLRK 183
Query: 178 SRT--ARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEE 222
SR + +++L+QQ+ Y++DF ER+DRER +EL++
Sbjct: 184 SRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQ 230
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 47.8 bits (112), Expect = 1e-05
Identities = 45/158 (28%), Positives = 78/158 (49%), Gaps = 33/158 (20%)
Query: 99 LQEENRLLKQKVTHVEDLNAKWQ--------RYNASRDEYVRGLHAQLRGLQIPHEPELM 150
LQEEN+LL+Q+++ VEDL A+ + +YNA + + L + L+ L+
Sbjct: 79 LQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLV 138
Query: 151 RKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYK------DDFM 204
R+ + L RQL+E + A +++L A + + + VQ L+ +IL YK + +
Sbjct: 139 RQSV-ELRRQLQE---EQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQL 194
Query: 205 SERA---------------DRERAQSRIQELEEKVASL 227
ER+ D E A R++E +++ ASL
Sbjct: 195 LERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASL 232
Score = 43.1 bits (100), Expect = 3e-04
Identities = 48/251 (19%), Positives = 106/251 (42%), Gaps = 38/251 (15%)
Query: 1 MQQLLSQPQHERE---KEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHM 57
+Q+ L+ +H+R+ + + R++++E + ++ ++L E L
Sbjct: 1752 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1811
Query: 58 CQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLN 117
Q L + L +RQ +G + + ++KLQ+E RLL++++ ++
Sbjct: 1812 LQQLREVLRQRQ-----------------EGEAAALNTVQKLQDERRLLQERLGSLQRAL 1854
Query: 118 AKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELA- 176
A+ + A + E R L++ + +R+ + ++ R+ D + E
Sbjct: 1855 AQLE---AEKREVERS------ALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGR 1905
Query: 177 ASRTARDAALE------RVQMLEQQILAYKDDFMSER--ADRERAQSRIQELEEKVASLL 228
RT A LE ++Q LE Q++ + + D ++ Q +Q+ E++ S
Sbjct: 1906 LDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQ 1965
Query: 229 HQVSWRQDSRE 239
Q ++RE
Sbjct: 1966 AQTERTLEARE 1976
Score = 42.4 bits (98), Expect = 6e-04
Identities = 45/210 (21%), Positives = 90/210 (42%), Gaps = 24/210 (11%)
Query: 43 ETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDG----HTSVQSVIEK 98
+ +R A+ + L K L + + +R + E+ + TDG H Q +++
Sbjct: 534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQR 593
Query: 99 LQEENRLLKQKVTHV-----------EDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEP 147
L+ N LL ++ +++ E+L + ++ A+++E L Q L+ E
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEE----LRRQRDRLEEEQED 649
Query: 148 EL-----MRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDD 202
+ +R+E+ R +RQLE+ + + +EL R A A + ML+ + +
Sbjct: 650 AVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEA 709
Query: 203 FMSERADRERAQSRIQELEEKVASLLHQVS 232
A R + + +L + ASL +S
Sbjct: 710 LTKAEAGRVELELSMTKLRAEEASLQDSLS 739
Score = 37.0 bits (84), Expect = 0.024
Identities = 63/283 (22%), Positives = 112/283 (39%), Gaps = 26/283 (9%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERAR----------AASDVLCRSLANETHQLR--- 48
+Q L Q + E +++V L R+ E E A++ R+L+ E +LR
Sbjct: 847 EQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 906
Query: 49 RTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSV--QSVI---EKLQEEN 103
L + Q L+ R+ G+ E G + Q +I EK +
Sbjct: 907 EALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDK 966
Query: 104 RLLKQKVTHVE-DLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLE 162
L+ QK+ E + A + A+ +E ++ L + E E + + S+L R+ E
Sbjct: 967 ELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ-SQLQREQE 1025
Query: 163 EKIN----DCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQ 218
E + + E+ +E+AA + RD L + +QQ L+ K+ + A E+
Sbjct: 1026 ELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES--EKTALSEKLMGTRH 1083
Query: 219 ELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
L + Q Q +E D ++A + + L A E
Sbjct: 1084 SLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREE 1126
Score = 34.7 bits (78), Expect = 0.12
Identities = 51/254 (20%), Positives = 103/254 (40%), Gaps = 33/254 (12%)
Query: 14 KEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQR 73
KE+V +R +++ RA D+L A L + + + K E Q
Sbjct: 680 KELVEVREALS---RATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQD 736
Query: 74 NVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLK-------QKVTHVEDLNAKWQRYNAS 126
++ + S + ++ +L+EE L+ Q+ T + + +
Sbjct: 737 SLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLE 796
Query: 127 RDEYVRGLHAQLRGL---------QIP---HEPELMRKEISRLNRQLEEKINDCAEVKQE 174
++ +GL LR Q+P HE +++++++L+RQL + + + ++E
Sbjct: 797 QEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARRE 856
Query: 175 L-----AASRTARD---AALERVQMLEQQILAYKDD-FMSERADRERAQSRIQELEEKVA 225
A R AR+ A E + Q + A ++ +SE A R R + + LE +
Sbjct: 857 AQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK--EALEGSLF 914
Query: 226 SLLHQVSWRQDSRE 239
+ Q++ + RE
Sbjct: 915 EVQRQLAQLEARRE 928
Score = 32.7 bits (73), Expect = 0.44
Identities = 45/230 (19%), Positives = 93/230 (40%), Gaps = 28/230 (12%)
Query: 2 QQLLSQPQHERE---KEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMC 58
+Q LS+ + + ++V LR +A+ E R ++ + L Q + A +
Sbjct: 1774 RQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTV 1833
Query: 59 QHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVED--- 115
Q L DER+ Q +G ++ V+ +L+++ L++ + VE
Sbjct: 1834 QKLQ---DERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKL 1890
Query: 116 --------LNAKWQRYN----------ASRDEYVRGLHAQLRGLQIPHEPELMRKEISRL 157
L+A+ R + A ++ L AQ+ L+ H P + + +
Sbjct: 1891 RSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQ 1950
Query: 158 NRQLEEKINDCAEVKQELAASRTARDAA-LERVQMLEQQILAYKDDFMSE 206
+L++++ + + + AR+ A +RV+ LE+Q+ K E
Sbjct: 1951 QLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQLQQE 2000
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 47.8 bits (112), Expect = 1e-05
Identities = 60/270 (22%), Positives = 108/270 (40%), Gaps = 47/270 (17%)
Query: 3 QLLSQPQHEREK---EVVLLRRSMAEGERARAASDVLCRSLANETH-------------- 45
Q + +H+++K +V L+ ++GERARA + L NE
Sbjct: 1245 QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1304
Query: 46 QLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRL 105
+L + + + + Q + L E + NV + E + S+ ++L EE
Sbjct: 1305 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN------SLQDQLDEEMEA 1358
Query: 106 LKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKI 165
+ H+ LN + ++ + A G + +KEI L +Q EEK
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG------KKRFQKEIENLTQQYEEKA 1412
Query: 166 NDCAEVKQELAASRTARD---------------AALERVQMLEQQILAYKDDFMSERAD- 209
A K E +R ++ + LE+ Q Q+LA + + S+ AD
Sbjct: 1413 --AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADE 1470
Query: 210 RERAQSRIQELEEKVASLLHQVSWRQDSRE 239
R+RA++ +E E K SL + +++E
Sbjct: 1471 RDRAEAEAREKETKALSLARALEEALEAKE 1500
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 26/166 (15%)
Query: 98 KLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIP-HEPELMRKEISR 156
KL +E +LL+++++ + A+ + + + + + L++ + E R+E+ +
Sbjct: 996 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK 1055
Query: 157 LNRQLEEKIND-----------CAEVKQELAASRTARDAALER--------------VQM 191
L R+LE +D AE+K +LA AAL R ++
Sbjct: 1056 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE 1115
Query: 192 LEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDS 237
LE I ++D SERA R +A+ + ++L E++ +L ++ DS
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS 1161
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 19/170 (11%)
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW 120
L K + +Q A+ + E S+ T+ +Q E+LQ E L + E++ +
Sbjct: 861 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQ---EQLQAETELYAE----AEEMRVRL 913
Query: 121 QRYNASRDEYVRGLHAQL-----RGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+E + + A+L RG Q+ E RK++++ LEE++ + +Q+L
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAE----RKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
+ +A +++ LE +IL D +R+ + RI +L +A
Sbjct: 970 QLEKVTAEA---KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Score = 38.5 bits (88), Expect = 0.008
Identities = 49/262 (18%), Positives = 109/262 (41%), Gaps = 30/262 (11%)
Query: 11 EREKEVVLLRRSMAEGERARAASDVLCRSLANETHQL---RRTLTATAHMCQHLAKCLDE 67
E+E + + L R++ E A+ + + L E L + + H + + L+
Sbjct: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1539
Query: 68 RQHAQRNVGERSPDQSEHTDG----------------HTSVQSVIEKLQEENRLLKQKVT 111
+ + E D+ + T+ +Q+ E+ +E+ R L++++
Sbjct: 1540 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 112 HVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELM-RKEISRLNRQLEEKINDCAE 170
E ++ A + L L+ L++ + + R+E + R+L+ ++ D
Sbjct: 1600 EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD--- 1656
Query: 171 VKQELAASRTARDAAL-------ERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEK 223
++EL +R +RD ++ + LE ++ ++D + R++A +EL E+
Sbjct: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
Query: 224 VASLLHQVSWRQDSREPDAGRI 245
+AS L + QD + RI
Sbjct: 1717 LASSLSGRNALQDEKRRLEARI 1738
Score = 38.5 bits (88), Expect = 0.008
Identities = 52/233 (22%), Positives = 97/233 (41%), Gaps = 42/233 (18%)
Query: 34 DVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQ 93
D+ R NE + RR L H ++ + DER+ + + + D
Sbjct: 1579 DLQARDEQNE--EKRRQLQRQLH--EYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Query: 94 SVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEY----------VRGLHAQLRGLQI 143
S I+ +E + L++ ++D + + ASRDE + L A L LQ
Sbjct: 1635 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1694
Query: 144 P-------------HEPELMRKEISRLN---------RQLEEKINDCAEVKQELAASRTA 181
+ EL + S L+ R+LE +I A++++EL +
Sbjct: 1695 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGN 1751
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELE---EKVASLLHQV 231
+A +RV+ QQ ++ +ER+ ++ +S Q+LE +++ S LH++
Sbjct: 1752 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1804
Score = 32.7 bits (73), Expect = 0.44
Identities = 43/222 (19%), Positives = 98/222 (44%), Gaps = 26/222 (11%)
Query: 13 EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQ 72
E +++ L+ +A ERAR +D+ LA E L +L+ + DE++ +
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEE---LASSLSGRNAL-------QDEKRRLE 1735
Query: 73 RNVGERSPDQSEHTDGHTSVQSVIEKLQEE-----NRLLKQKVTHVEDLNAKWQRYNASR 127
+ + + E ++ + K ++ N L ++ T ++ +A+ Q+
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR-QQLERQN 1794
Query: 128 DEYVRGLHAQLRGLQIPHEPEL--MRKEISRLNRQLEEKINDCAEVKQELAASRTARDAA 185
E LH ++ + + + +I++L Q+E++ A KQ S +D
Sbjct: 1795 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE----AREKQAATKSLKQKDKK 1850
Query: 186 LERV--QMLEQQILA--YKDDFMSERADRERAQSRIQELEEK 223
L+ + Q+ +++ +A YK+ A ++ + +++E EE+
Sbjct: 1851 LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE 1892
Score = 29.6 bits (65), Expect = 3.8
Identities = 17/77 (22%), Positives = 39/77 (50%)
Query: 186 LERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRI 245
L +V E+++ A +D+ + +++A++ ++ELE+K + L + + Q+ + +
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 246 HAGSKTAKYLAADALEL 262
+ LAA EL
Sbjct: 904 AEAEEMRVRLAAKKQEL 920
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 47.8 bits (112), Expect = 1e-05
Identities = 60/270 (22%), Positives = 108/270 (40%), Gaps = 47/270 (17%)
Query: 3 QLLSQPQHEREK---EVVLLRRSMAEGERARAASDVLCRSLANETH-------------- 45
Q + +H+++K +V L+ ++GERARA + L NE
Sbjct: 1252 QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1311
Query: 46 QLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRL 105
+L + + + + Q + L E + NV + E + S+ ++L EE
Sbjct: 1312 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN------SLQDQLDEEMEA 1365
Query: 106 LKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKI 165
+ H+ LN + ++ + A G + +KEI L +Q EEK
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG------KKRFQKEIENLTQQYEEKA 1419
Query: 166 NDCAEVKQELAASRTARD---------------AALERVQMLEQQILAYKDDFMSERAD- 209
A K E +R ++ + LE+ Q Q+LA + + S+ AD
Sbjct: 1420 --AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADE 1477
Query: 210 RERAQSRIQELEEKVASLLHQVSWRQDSRE 239
R+RA++ +E E K SL + +++E
Sbjct: 1478 RDRAEAEAREKETKALSLARALEEALEAKE 1507
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 26/166 (15%)
Query: 98 KLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIP-HEPELMRKEISR 156
KL +E +LL+++++ + A+ + + + + + L++ + E R+E+ +
Sbjct: 1003 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK 1062
Query: 157 LNRQLEEKIND-----------CAEVKQELAASRTARDAALER--------------VQM 191
L R+LE +D AE+K +LA AAL R ++
Sbjct: 1063 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE 1122
Query: 192 LEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDS 237
LE I ++D SERA R +A+ + ++L E++ +L ++ DS
Sbjct: 1123 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS 1168
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 19/170 (11%)
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW 120
L K + +Q A+ + E S+ T+ +Q E+LQ E L + E++ +
Sbjct: 868 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQ---EQLQAETELYAE----AEEMRVRL 920
Query: 121 QRYNASRDEYVRGLHAQL-----RGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+E + + A+L RG Q+ E RK++++ LEE++ + +Q+L
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAE----RKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
+ +A +++ LE +IL D +R+ + RI +L +A
Sbjct: 977 QLEKVTAEA---KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Score = 38.5 bits (88), Expect = 0.008
Identities = 49/262 (18%), Positives = 109/262 (41%), Gaps = 30/262 (11%)
Query: 11 EREKEVVLLRRSMAEGERARAASDVLCRSLANETHQL---RRTLTATAHMCQHLAKCLDE 67
E+E + + L R++ E A+ + + L E L + + H + + L+
Sbjct: 1487 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1546
Query: 68 RQHAQRNVGERSPDQSEHTDG----------------HTSVQSVIEKLQEENRLLKQKVT 111
+ + E D+ + T+ +Q+ E+ +E+ R L++++
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 112 HVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELM-RKEISRLNRQLEEKINDCAE 170
E ++ A + L L+ L++ + + R+E + R+L+ ++ D
Sbjct: 1607 EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD--- 1663
Query: 171 VKQELAASRTARDAAL-------ERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEK 223
++EL +R +RD ++ + LE ++ ++D + R++A +EL E+
Sbjct: 1664 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723
Query: 224 VASLLHQVSWRQDSREPDAGRI 245
+AS L + QD + RI
Sbjct: 1724 LASSLSGRNALQDEKRRLEARI 1745
Score = 38.5 bits (88), Expect = 0.008
Identities = 52/233 (22%), Positives = 97/233 (41%), Gaps = 42/233 (18%)
Query: 34 DVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQ 93
D+ R NE + RR L H ++ + DER+ + + + D
Sbjct: 1586 DLQARDEQNE--EKRRQLQRQLH--EYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 94 SVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEY----------VRGLHAQLRGLQI 143
S I+ +E + L++ ++D + + ASRDE + L A L LQ
Sbjct: 1642 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1701
Query: 144 P-------------HEPELMRKEISRLN---------RQLEEKINDCAEVKQELAASRTA 181
+ EL + S L+ R+LE +I A++++EL +
Sbjct: 1702 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGN 1758
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELE---EKVASLLHQV 231
+A +RV+ QQ ++ +ER+ ++ +S Q+LE +++ S LH++
Sbjct: 1759 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1811
Score = 32.7 bits (73), Expect = 0.44
Identities = 43/222 (19%), Positives = 98/222 (44%), Gaps = 26/222 (11%)
Query: 13 EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQ 72
E +++ L+ +A ERAR +D+ LA E L +L+ + DE++ +
Sbjct: 1693 EADLMQLQEDLAAAERARKQADLEKEELAEE---LASSLSGRNAL-------QDEKRRLE 1742
Query: 73 RNVGERSPDQSEHTDGHTSVQSVIEKLQEE-----NRLLKQKVTHVEDLNAKWQRYNASR 127
+ + + E ++ + K ++ N L ++ T ++ +A+ Q+
Sbjct: 1743 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR-QQLERQN 1801
Query: 128 DEYVRGLHAQLRGLQIPHEPEL--MRKEISRLNRQLEEKINDCAEVKQELAASRTARDAA 185
E LH ++ + + + +I++L Q+E++ A KQ S +D
Sbjct: 1802 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE----AREKQAATKSLKQKDKK 1857
Query: 186 LERV--QMLEQQILA--YKDDFMSERADRERAQSRIQELEEK 223
L+ + Q+ +++ +A YK+ A ++ + +++E EE+
Sbjct: 1858 LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE 1899
Score = 29.6 bits (65), Expect = 3.8
Identities = 17/77 (22%), Positives = 39/77 (50%)
Query: 186 LERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRI 245
L +V E+++ A +D+ + +++A++ ++ELE+K + L + + Q+ + +
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 246 HAGSKTAKYLAADALEL 262
+ LAA EL
Sbjct: 911 AEAEEMRVRLAAKKQEL 927
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 47.8 bits (112), Expect = 1e-05
Identities = 60/270 (22%), Positives = 108/270 (40%), Gaps = 47/270 (17%)
Query: 3 QLLSQPQHEREK---EVVLLRRSMAEGERARAASDVLCRSLANETH-------------- 45
Q + +H+++K +V L+ ++GERARA + L NE
Sbjct: 1252 QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1311
Query: 46 QLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRL 105
+L + + + + Q + L E + NV + E + S+ ++L EE
Sbjct: 1312 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN------SLQDQLDEEMEA 1365
Query: 106 LKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKI 165
+ H+ LN + ++ + A G + +KEI L +Q EEK
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG------KKRFQKEIENLTQQYEEKA 1419
Query: 166 NDCAEVKQELAASRTARD---------------AALERVQMLEQQILAYKDDFMSERAD- 209
A K E +R ++ + LE+ Q Q+LA + + S+ AD
Sbjct: 1420 --AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADE 1477
Query: 210 RERAQSRIQELEEKVASLLHQVSWRQDSRE 239
R+RA++ +E E K SL + +++E
Sbjct: 1478 RDRAEAEAREKETKALSLARALEEALEAKE 1507
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 26/166 (15%)
Query: 98 KLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIP-HEPELMRKEISR 156
KL +E +LL+++++ + A+ + + + + + L++ + E R+E+ +
Sbjct: 1003 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK 1062
Query: 157 LNRQLEEKIND-----------CAEVKQELAASRTARDAALER--------------VQM 191
L R+LE +D AE+K +LA AAL R ++
Sbjct: 1063 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE 1122
Query: 192 LEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDS 237
LE I ++D SERA R +A+ + ++L E++ +L ++ DS
Sbjct: 1123 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS 1168
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 19/170 (11%)
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW 120
L K + +Q A+ + E S+ T+ +Q E+LQ E L + E++ +
Sbjct: 868 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQ---EQLQAETELYAE----AEEMRVRL 920
Query: 121 QRYNASRDEYVRGLHAQL-----RGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+E + + A+L RG Q+ E RK++++ LEE++ + +Q+L
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAE----RKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
+ +A +++ LE +IL D +R+ + RI +L +A
Sbjct: 977 QLEKVTAEA---KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Score = 38.5 bits (88), Expect = 0.008
Identities = 49/262 (18%), Positives = 109/262 (41%), Gaps = 30/262 (11%)
Query: 11 EREKEVVLLRRSMAEGERARAASDVLCRSLANETHQL---RRTLTATAHMCQHLAKCLDE 67
E+E + + L R++ E A+ + + L E L + + H + + L+
Sbjct: 1487 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1546
Query: 68 RQHAQRNVGERSPDQSEHTDG----------------HTSVQSVIEKLQEENRLLKQKVT 111
+ + E D+ + T+ +Q+ E+ +E+ R L++++
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 112 HVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELM-RKEISRLNRQLEEKINDCAE 170
E ++ A + L L+ L++ + + R+E + R+L+ ++ D
Sbjct: 1607 EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD--- 1663
Query: 171 VKQELAASRTARDAAL-------ERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEK 223
++EL +R +RD ++ + LE ++ ++D + R++A +EL E+
Sbjct: 1664 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1723
Query: 224 VASLLHQVSWRQDSREPDAGRI 245
+AS L + QD + RI
Sbjct: 1724 LASSLSGRNALQDEKRRLEARI 1745
Score = 38.5 bits (88), Expect = 0.008
Identities = 52/233 (22%), Positives = 97/233 (41%), Gaps = 42/233 (18%)
Query: 34 DVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQ 93
D+ R NE + RR L H ++ + DER+ + + + D
Sbjct: 1586 DLQARDEQNE--EKRRQLQRQLH--EYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 94 SVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEY----------VRGLHAQLRGLQI 143
S I+ +E + L++ ++D + + ASRDE + L A L LQ
Sbjct: 1642 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1701
Query: 144 P-------------HEPELMRKEISRLN---------RQLEEKINDCAEVKQELAASRTA 181
+ EL + S L+ R+LE +I A++++EL +
Sbjct: 1702 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGN 1758
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELE---EKVASLLHQV 231
+A +RV+ QQ ++ +ER+ ++ +S Q+LE +++ S LH++
Sbjct: 1759 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1811
Score = 32.7 bits (73), Expect = 0.44
Identities = 43/222 (19%), Positives = 98/222 (44%), Gaps = 26/222 (11%)
Query: 13 EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQ 72
E +++ L+ +A ERAR +D+ LA E L +L+ + DE++ +
Sbjct: 1693 EADLMQLQEDLAAAERARKQADLEKEELAEE---LASSLSGRNAL-------QDEKRRLE 1742
Query: 73 RNVGERSPDQSEHTDGHTSVQSVIEKLQEE-----NRLLKQKVTHVEDLNAKWQRYNASR 127
+ + + E ++ + K ++ N L ++ T ++ +A+ Q+
Sbjct: 1743 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR-QQLERQN 1801
Query: 128 DEYVRGLHAQLRGLQIPHEPEL--MRKEISRLNRQLEEKINDCAEVKQELAASRTARDAA 185
E LH ++ + + + +I++L Q+E++ A KQ S +D
Sbjct: 1802 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE----AREKQAATKSLKQKDKK 1857
Query: 186 LERV--QMLEQQILA--YKDDFMSERADRERAQSRIQELEEK 223
L+ + Q+ +++ +A YK+ A ++ + +++E EE+
Sbjct: 1858 LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE 1899
Score = 29.6 bits (65), Expect = 3.8
Identities = 17/77 (22%), Positives = 39/77 (50%)
Query: 186 LERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRI 245
L +V E+++ A +D+ + +++A++ ++ELE+K + L + + Q+ + +
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 246 HAGSKTAKYLAADALEL 262
+ LAA EL
Sbjct: 911 AEAEEMRVRLAAKKQEL 927
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 47.8 bits (112), Expect = 1e-05
Identities = 60/270 (22%), Positives = 108/270 (40%), Gaps = 47/270 (17%)
Query: 3 QLLSQPQHEREK---EVVLLRRSMAEGERARAASDVLCRSLANETH-------------- 45
Q + +H+++K +V L+ ++GERARA + L NE
Sbjct: 1245 QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1304
Query: 46 QLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRL 105
+L + + + + Q + L E + NV + E + S+ ++L EE
Sbjct: 1305 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN------SLQDQLDEEMEA 1358
Query: 106 LKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKI 165
+ H+ LN + ++ + A G + +KEI L +Q EEK
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG------KKRFQKEIENLTQQYEEKA 1412
Query: 166 NDCAEVKQELAASRTARD---------------AALERVQMLEQQILAYKDDFMSERAD- 209
A K E +R ++ + LE+ Q Q+LA + + S+ AD
Sbjct: 1413 --AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADE 1470
Query: 210 RERAQSRIQELEEKVASLLHQVSWRQDSRE 239
R+RA++ +E E K SL + +++E
Sbjct: 1471 RDRAEAEAREKETKALSLARALEEALEAKE 1500
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 26/166 (15%)
Query: 98 KLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIP-HEPELMRKEISR 156
KL +E +LL+++++ + A+ + + + + + L++ + E R+E+ +
Sbjct: 996 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK 1055
Query: 157 LNRQLEEKIND-----------CAEVKQELAASRTARDAALER--------------VQM 191
L R+LE +D AE+K +LA AAL R ++
Sbjct: 1056 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE 1115
Query: 192 LEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDS 237
LE I ++D SERA R +A+ + ++L E++ +L ++ DS
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS 1161
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 19/170 (11%)
Query: 61 LAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKW 120
L K + +Q A+ + E S+ T+ +Q E+LQ E L + E++ +
Sbjct: 861 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQ---EQLQAETELYAE----AEEMRVRL 913
Query: 121 QRYNASRDEYVRGLHAQL-----RGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQEL 175
+E + + A+L RG Q+ E RK++++ LEE++ + +Q+L
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAE----RKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 176 AASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVA 225
+ +A +++ LE +IL D +R+ + RI +L +A
Sbjct: 970 QLEKVTAEA---KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Score = 38.5 bits (88), Expect = 0.008
Identities = 49/262 (18%), Positives = 109/262 (41%), Gaps = 30/262 (11%)
Query: 11 EREKEVVLLRRSMAEGERARAASDVLCRSLANETHQL---RRTLTATAHMCQHLAKCLDE 67
E+E + + L R++ E A+ + + L E L + + H + + L+
Sbjct: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1539
Query: 68 RQHAQRNVGERSPDQSEHTDG----------------HTSVQSVIEKLQEENRLLKQKVT 111
+ + E D+ + T+ +Q+ E+ +E+ R L++++
Sbjct: 1540 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 112 HVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELM-RKEISRLNRQLEEKINDCAE 170
E ++ A + L L+ L++ + + R+E + R+L+ ++ D
Sbjct: 1600 EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD--- 1656
Query: 171 VKQELAASRTARDAAL-------ERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEK 223
++EL +R +RD ++ + LE ++ ++D + R++A +EL E+
Sbjct: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
Query: 224 VASLLHQVSWRQDSREPDAGRI 245
+AS L + QD + RI
Sbjct: 1717 LASSLSGRNALQDEKRRLEARI 1738
Score = 38.5 bits (88), Expect = 0.008
Identities = 52/233 (22%), Positives = 97/233 (41%), Gaps = 42/233 (18%)
Query: 34 DVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQ 93
D+ R NE + RR L H ++ + DER+ + + + D
Sbjct: 1579 DLQARDEQNE--EKRRQLQRQLH--EYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Query: 94 SVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEY----------VRGLHAQLRGLQI 143
S I+ +E + L++ ++D + + ASRDE + L A L LQ
Sbjct: 1635 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1694
Query: 144 P-------------HEPELMRKEISRLN---------RQLEEKINDCAEVKQELAASRTA 181
+ EL + S L+ R+LE +I A++++EL +
Sbjct: 1695 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGN 1751
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELE---EKVASLLHQV 231
+A +RV+ QQ ++ +ER+ ++ +S Q+LE +++ S LH++
Sbjct: 1752 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1804
Score = 32.7 bits (73), Expect = 0.44
Identities = 43/222 (19%), Positives = 98/222 (44%), Gaps = 26/222 (11%)
Query: 13 EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQ 72
E +++ L+ +A ERAR +D+ LA E L +L+ + DE++ +
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEE---LASSLSGRNAL-------QDEKRRLE 1735
Query: 73 RNVGERSPDQSEHTDGHTSVQSVIEKLQEE-----NRLLKQKVTHVEDLNAKWQRYNASR 127
+ + + E ++ + K ++ N L ++ T ++ +A+ Q+
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR-QQLERQN 1794
Query: 128 DEYVRGLHAQLRGLQIPHEPEL--MRKEISRLNRQLEEKINDCAEVKQELAASRTARDAA 185
E LH ++ + + + +I++L Q+E++ A KQ S +D
Sbjct: 1795 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE----AREKQAATKSLKQKDKK 1850
Query: 186 LERV--QMLEQQILA--YKDDFMSERADRERAQSRIQELEEK 223
L+ + Q+ +++ +A YK+ A ++ + +++E EE+
Sbjct: 1851 LKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE 1892
Score = 29.6 bits (65), Expect = 3.8
Identities = 17/77 (22%), Positives = 39/77 (50%)
Query: 186 LERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRI 245
L +V E+++ A +D+ + +++A++ ++ELE+K + L + + Q+ + +
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 246 HAGSKTAKYLAADALEL 262
+ LAA EL
Sbjct: 904 AEAEEMRVRLAAKKQEL 920
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 47.8 bits (112), Expect = 1e-05
Identities = 57/247 (23%), Positives = 107/247 (43%), Gaps = 37/247 (14%)
Query: 7 QPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLD 66
Q QHE + +V L + ++ + +A E QL+ L A + L+
Sbjct: 664 QEQHEAQAQVAELELQLRSEQQKATEKE----RVAQEKDQLQEQLQALKESLKVTKGSLE 719
Query: 67 ERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNAS 126
E + R+ D E Q I +L+ E R L ++ H + + + A
Sbjct: 720 EEKR-------RAADALEEQ------QRCISELKAETRSLVEQ--HKRE-RKELEEERAG 763
Query: 127 RDEYVRGLHAQLRGLQIPH--EPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA-RD 183
R +GL A+L+ L H E E++R+E++ ++C ++ +E+AA R D
Sbjct: 764 R----KGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYED 819
Query: 184 AALERVQ---MLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREP 240
+ E Q M ++Q++ K++ E+A+ +QE +EKVA + + ++
Sbjct: 820 SQQEEAQYGAMFQEQLMTLKEEC-------EKARQELQEAKEKVAGIESHSELQISRQQN 872
Query: 241 DAGRIHA 247
+ +HA
Sbjct: 873 ELAELHA 879
Score = 42.7 bits (99), Expect = 4e-04
Identities = 60/254 (23%), Positives = 95/254 (37%), Gaps = 30/254 (11%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGE-----RARAASDVLCRSLANETH--------QLR 48
QQ + Q ERE + R A+ + ARA ++ ++ NE L
Sbjct: 994 QQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALA 1053
Query: 49 RTLTATAHMCQHLAKC----------LDERQHAQRNVGER-SPDQSEHTDGHTSVQSVIE 97
LT Q LAK L+E + + + E+ + + EH G +
Sbjct: 1054 HALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAG 1113
Query: 98 KLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRL 157
+ + L+ V L + Q+ D R L A+ R + + L L
Sbjct: 1114 RTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAE-RASRAERDSAL-----ETL 1167
Query: 158 NRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRI 217
QLEEK + + LA+++ A +VQ + +K R + ER S I
Sbjct: 1168 QGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLI 1227
Query: 218 QELEEKVASLLHQV 231
LEE+V+ L QV
Sbjct: 1228 SSLEEEVSILNRQV 1241
Score = 41.2 bits (95), Expect = 0.001
Identities = 51/228 (22%), Positives = 95/228 (41%), Gaps = 26/228 (11%)
Query: 5 LSQPQHEREKEVVLLRRSMAEGERARAAS-----DVLCRSLANETHQLRRTLTATAHMCQ 59
L Q +++++ L RS+ E ERA A + L L + +L + +A A +
Sbjct: 1132 LEQQCQKQQEQADSLERSL-EAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQR 1190
Query: 60 HLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAK 119
LA + Q + E + S+I L+EE +L ++V E + +
Sbjct: 1191 ELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKE 1250
Query: 120 WQRYNASRDEYVRGLHAQLRGLQIP---------HEPELMRKEISRLNRQLEEKINDCAE 170
+R + E + L +LR LQ +R+E+ L + E++
Sbjct: 1251 LKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASEN 1310
Query: 171 VKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQ 218
++QEL + ER + L Q++ A+++ F +E+A S +Q
Sbjct: 1311 LRQELTSQ-------AERAEELGQELKAWQEKFF----QKEQALSTLQ 1347
Score = 37.4 bits (85), Expect = 0.018
Identities = 59/254 (23%), Positives = 105/254 (41%), Gaps = 28/254 (11%)
Query: 11 EREKEVVLLRRSMAEGERARAASDVLCRSLANETHQ-------LRRTLTATAHMCQHLAK 63
E + V L+ +A+ E+ A+ A T LR ++ CQ K
Sbjct: 1082 ELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQ---K 1138
Query: 64 CLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEE----NRLLKQKVTHVEDLNAK 119
++ +R++ ++E ++Q +E+ +E L + K
Sbjct: 1139 QQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTK 1198
Query: 120 WQRYNASRDEYVRGLHAQL-RGLQIPHEPELM----RKEISRLNRQLEEKINDCAEVKQE 174
Q ++ + DE+ AQ+ RG Q + +E+S LNRQ+ EK + E+K+
Sbjct: 1199 VQDHSKAEDEW----KAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL 1254
Query: 175 LAASRTARDAALERVQMLEQQILAYKDDFMSERAD--RERAQSRIQELE-EKVAS-LLHQ 230
+ A ER+++L+ + A +ER+ RE QS +E E ++VAS L Q
Sbjct: 1255 VMAESEKSQKLEERLRLLQAE-TASNSARAAERSSALREEVQSLREEAEKQRVASENLRQ 1313
Query: 231 VSWRQDSREPDAGR 244
Q R + G+
Sbjct: 1314 ELTSQAERAEELGQ 1327
Score = 32.7 bits (73), Expect = 0.44
Identities = 52/228 (22%), Positives = 94/228 (41%), Gaps = 23/228 (10%)
Query: 40 LANETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQS----EHTDGHTSVQSV 95
L ++ L L T CQ L + + E + D S E +Q
Sbjct: 281 LRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDA 340
Query: 96 IEKLQEEN-----RLLKQKVTHVEDLNAKWQRYNA--SRDEYVRGLHAQLRG--LQIPHE 146
+ +L EE+ L+++ ++L+A Q ++E ++G +QL Q+
Sbjct: 341 LNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDN 400
Query: 147 PELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALE-RVQMLEQQILAYKDDFMS 205
P + E+ QLE +KQE AA+ A + L+ RV+MLE + + ++
Sbjct: 401 PPQEKGEVLGDVLQLET-------LKQE-AATLAANNTQLQARVEMLETERGQQEAKLLA 452
Query: 206 ERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAK 253
ER E + ++ L + S + +S ++ E A + H TA+
Sbjct: 453 ERGHFEEEKQQLSSLITDLQSSISNLSQAKEELE-QASQAHGARLTAQ 499
Score = 31.6 bits (70), Expect = 0.99
Identities = 47/228 (20%), Positives = 95/228 (41%), Gaps = 38/228 (16%)
Query: 10 HEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQ 69
H+ E EV LRR +AE A+ ++ C L E R ++ Q
Sbjct: 778 HQAETEV--LRRELAEAMAAQHTAESECEQLVKEVAAWRER--------------YEDSQ 821
Query: 70 HAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDE 129
+ G +Q +++ EK ++E + K+KV +E + + + +
Sbjct: 822 QEEAQYGAMFQEQL------MTLKEECEKARQELQEAKEKVAGIESHS---ELQISRQQN 872
Query: 130 YVRGLHAQL-RGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALER 188
+ LHA L R LQ E E+ ++++ L+EK+ A +E+A T A E+
Sbjct: 873 ELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKM---AATSKEVARLETLVRKAGEQ 929
Query: 189 VQMLEQQILA-------YKDDFMSERADRE--RAQSRIQELEEKVASL 227
+ ++++ + +++ E+ R+ Q+ +Q +E + +
Sbjct: 930 QETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQM 977
>gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo
sapiens]
Length = 1638
Score = 47.8 bits (112), Expect = 1e-05
Identities = 60/248 (24%), Positives = 109/248 (43%), Gaps = 44/248 (17%)
Query: 5 LSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKC 64
LS+ E + V L+ S +G A+ D+ ++L E +LR+ +T ++H+ Q L +
Sbjct: 458 LSRKLQESTQTVQALQYSTVDGPLT-ASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEA 516
Query: 65 LDERQHAQRNVGERSPDQSEHTDGHTSVQSV---IEKLQEENRLLKQKVTHVEDLNA--- 118
RQ E D +++ I+ LQ+E L + H E L A
Sbjct: 517 NAVRQ--------------ELDDAFRQIKAYEKQIKTLQQEREDLNKLEVHTEALAAEAS 562
Query: 119 KWQRYNASRDEYVRGLHAQLRGL---QIPHEPELM----RKEISRLNRQLEEK------- 164
K ++ + Y + L +L GL QI + P + ++EI++L LE+K
Sbjct: 563 KDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEE 622
Query: 165 --------INDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSR 216
N+ +K+EL S + A + + +L+ ++ + + SER + E ++ +
Sbjct: 623 LSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFE-SEFK 681
Query: 217 IQELEEKV 224
Q EKV
Sbjct: 682 QQYEREKV 689
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 47.4 bits (111), Expect = 2e-05
Identities = 36/133 (27%), Positives = 66/133 (49%), Gaps = 13/133 (9%)
Query: 94 SVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKE 153
+V + L+E+ +KQ+ + V+DL + QR N + ++ L AQ + Q+ + + ++
Sbjct: 37 NVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTN----LQKLQAQKQ--QVQELLDELDEQ 90
Query: 154 ISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERA 213
++L QL+E CAE Q +++ + + E QI Y+++ R + R
Sbjct: 91 KAQLEEQLKEVRKKCAEEAQLISSLKA-------ELTSQESQISTYEEELAKAREELSRL 143
Query: 214 QSRIQELEEKVAS 226
Q ELEE V S
Sbjct: 144 QQETAELEESVES 156
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 46.6 bits (109), Expect = 3e-05
Identities = 54/274 (19%), Positives = 115/274 (41%), Gaps = 33/274 (12%)
Query: 13 EKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKC-------L 65
E+++ R + GE A + L E QL L A+ LA L
Sbjct: 743 EQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARL 802
Query: 66 DERQHAQRNVGERSPDQSEHTDGHTSVQSVIEK----LQEENRLLKQKVTHVEDLNAKWQ 121
+E Q +G+ + + + V+ + L+E+ RLL + V + LN + +
Sbjct: 803 EEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTV---DRLNKELE 859
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAE----------- 170
+ + ++ L AQL + E R+E++ RQ ++ ++ +
Sbjct: 860 KIGEDSKQALQQLQAQLEDYK-----EKARREVADAQRQAKDWASEAEKTSGGLSRLQDE 914
Query: 171 ---VKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASL 227
++Q L AS+ RD A ++L Q++ + + +++ ++ +++ LEEKV+ L
Sbjct: 915 IQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRL 974
Query: 228 LHQVSWRQDSREPDAGRIHAGSKTAKYLAADALE 261
++ +++ E R++ G L + ++
Sbjct: 975 ETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQ 1008
Score = 43.9 bits (102), Expect = 2e-04
Identities = 51/241 (21%), Positives = 100/241 (41%), Gaps = 11/241 (4%)
Query: 2 QQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHL 61
QQ L++ E K+ +LRR AE E + D L E ++ Q
Sbjct: 816 QQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQ-- 873
Query: 62 AKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQ 121
A+ D ++ A+R V + + + +LQ+E + L+Q + ++ +
Sbjct: 874 AQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQA-----SQAE 928
Query: 122 RYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTA 181
R A D+ + L +L+GL+ E E ++ RQL+ + ++ EL +
Sbjct: 929 RDTARLDKEL--LAQRLQGLE--QEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNT 984
Query: 182 RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPD 241
+ +RV Q+ + + M ER+ R+ + LE + L +++ + ++P
Sbjct: 985 VELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPS 1044
Query: 242 A 242
A
Sbjct: 1045 A 1045
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 46.2 bits (108), Expect = 4e-05
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 20/179 (11%)
Query: 93 QSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASR--DEYVRGLHAQLRGLQIPHEPELM 150
Q +E Q EN+LLK KV ++ NA+ R + +Y L + R + E E +
Sbjct: 210 QRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR--KHSAEKEAL 267
Query: 151 RKEISRLNRQLEE--KINDCAEVKQELAASRTAR-DAALERVQ----MLEQQILAYKDDF 203
+E + + +EE K AE+ E R D +ER++ L+ Q+L ++ +
Sbjct: 268 LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEM 327
Query: 204 MSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALEL 262
E D ++ R Q+LEE ASL ++ D +H K K + + EL
Sbjct: 328 SGELTDSDK--ERYQQLEEASASLRERIRHLDD-------MVHCQQKKVKQMVEENNEL 377
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.128 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,056,967
Number of Sequences: 37866
Number of extensions: 632139
Number of successful extensions: 5709
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 529
Number of HSP's that attempted gapping in prelim test: 4392
Number of HSP's gapped (non-prelim): 1608
length of query: 322
length of database: 18,247,518
effective HSP length: 102
effective length of query: 220
effective length of database: 14,385,186
effective search space: 3164740920
effective search space used: 3164740920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.