Search of human proteins with 239757765

Search of human proteins with 239757765

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo
sapiens]
         (233 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo ...   476   e-135
gi|5453549 peroxiredoxin 4 [Homo sapiens]                             404   e-113
gi|32455266 peroxiredoxin 1 [Homo sapiens]                            193   9e-50
gi|32455264 peroxiredoxin 1 [Homo sapiens]                            193   9e-50
gi|4505591 peroxiredoxin 1 [Homo sapiens]                             193   9e-50
gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]                  193   1e-49
gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]         176   2e-44
gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]                  176   2e-44
gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]                  127   8e-30
gi|4758638 peroxiredoxin 6 [Homo sapiens]                              47   1e-05
gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]      35   0.072
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi...    30   1.4  
gi|22748713 ankyrin repeat domain 9 [Homo sapiens]                     30   2.3  
gi|11055992 serine carboxypeptidase 1 precursor [Homo sapiens]         29   3.9  
gi|157276599 bactericidal/permeability-increasing protein precur...    28   5.2  
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]     28   6.7  

>gi|239757765 PREDICTED: similar to thioredoxin peroxidase [Homo
           sapiens]
          Length = 233

 Score =  476 bits (1226), Expect = e-135
 Identities = 233/233 (100%), Positives = 233/233 (100%)

Query: 1   MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY 60
           MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY
Sbjct: 1   MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY 60

Query: 61  PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF 120
           PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF
Sbjct: 61  PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF 120

Query: 121 TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWSVSYTYIRRKKRMDLLLKGLF 180
           TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWSVSYTYIRRKKRMDLLLKGLF
Sbjct: 121 TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWSVSYTYIRRKKRMDLLLKGLF 180

Query: 181 IIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWKAEVFR 233
           IIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWKAEVFR
Sbjct: 181 IIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWKAEVFR 233


>gi|5453549 peroxiredoxin 4 [Homo sapiens]
          Length = 271

 Score =  404 bits (1037), Expect = e-113
 Identities = 208/251 (82%), Positives = 212/251 (84%), Gaps = 24/251 (9%)

Query: 1   MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY 60
           MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY
Sbjct: 1   MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVY 60

Query: 61  PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF 120
           PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF
Sbjct: 61  PGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDF 120

Query: 121 TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAW--------------------- 159
           TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAW                     
Sbjct: 121 TFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDL 180

Query: 160 --SVSYTYIRRKKRMDLLLKGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDK 217
              +S  Y    +     L+GLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDK
Sbjct: 181 THQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDK 240

Query: 218 HGEDNPRSSWK 228
           HGE  P + WK
Sbjct: 241 HGEVCP-AGWK 250


>gi|32455266 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  193 bits (491), Expect = 9e-50
 Identities = 101/174 (58%), Positives = 122/174 (70%), Gaps = 25/174 (14%)

Query: 79  AKISKPAPYWEGTAVI-DGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEE 137
           AKI  PAP ++ TAV+ DG+FK++ L+DY+GKY+VFFFYPLDFTFVCPTEIIAF DR EE
Sbjct: 6   AKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEE 65

Query: 138 FRSINTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDL 174
           F+ +N +V+  SVDS F HLAW                       +++  Y   K    +
Sbjct: 66  FKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGI 125

Query: 175 LLKGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWK 228
             +GLFIIDDKGILRQIT+NDLPVGRSVDETLRLVQAFQ+TDKHGE  P + WK
Sbjct: 126 SFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCP-AGWK 178


>gi|32455264 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  193 bits (491), Expect = 9e-50
 Identities = 101/174 (58%), Positives = 122/174 (70%), Gaps = 25/174 (14%)

Query: 79  AKISKPAPYWEGTAVI-DGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEE 137
           AKI  PAP ++ TAV+ DG+FK++ L+DY+GKY+VFFFYPLDFTFVCPTEIIAF DR EE
Sbjct: 6   AKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEE 65

Query: 138 FRSINTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDL 174
           F+ +N +V+  SVDS F HLAW                       +++  Y   K    +
Sbjct: 66  FKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGI 125

Query: 175 LLKGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWK 228
             +GLFIIDDKGILRQIT+NDLPVGRSVDETLRLVQAFQ+TDKHGE  P + WK
Sbjct: 126 SFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCP-AGWK 178


>gi|4505591 peroxiredoxin 1 [Homo sapiens]
          Length = 199

 Score =  193 bits (491), Expect = 9e-50
 Identities = 101/174 (58%), Positives = 122/174 (70%), Gaps = 25/174 (14%)

Query: 79  AKISKPAPYWEGTAVI-DGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEE 137
           AKI  PAP ++ TAV+ DG+FK++ L+DY+GKY+VFFFYPLDFTFVCPTEIIAF DR EE
Sbjct: 6   AKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEE 65

Query: 138 FRSINTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDL 174
           F+ +N +V+  SVDS F HLAW                       +++  Y   K    +
Sbjct: 66  FKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGI 125

Query: 175 LLKGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWK 228
             +GLFIIDDKGILRQIT+NDLPVGRSVDETLRLVQAFQ+TDKHGE  P + WK
Sbjct: 126 SFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCP-AGWK 178


>gi|32189392 peroxiredoxin 2 isoform a [Homo sapiens]
          Length = 198

 Score =  193 bits (490), Expect = 1e-49
 Identities = 101/173 (58%), Positives = 120/173 (69%), Gaps = 24/173 (13%)

Query: 79  AKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEF 138
           A+I KPAP ++ TAV+DG FKE+KL+DY+GKY+V FFYPLDFTFVCPTEIIAF +R E+F
Sbjct: 6   ARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDF 65

Query: 139 RSINTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDLL 175
           R +  EV+  SVDSQFTHLAW                        +S  Y   K    + 
Sbjct: 66  RKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIA 125

Query: 176 LKGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWK 228
            +GLFIID KG+LRQIT+NDLPVGRSVDE LRLVQAFQYTD+HGE  P + WK
Sbjct: 126 YRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCP-AGWK 177


>gi|5802974 peroxiredoxin 3 isoform a precursor [Homo sapiens]
          Length = 256

 Score =  176 bits (446), Expect = 2e-44
 Identities = 88/170 (51%), Positives = 116/170 (68%), Gaps = 24/170 (14%)

Query: 81  ISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRS 140
           +++ APY++GTAV++GEFK+L L D++GKYLV FFYPLDFTFVCPTEI+AF D+  EF  
Sbjct: 65  VTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHD 124

Query: 141 INTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDLLLK 177
           +N EVVA SVDS F+HLAW                        +S  Y    +   L L+
Sbjct: 125 VNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALR 184

Query: 178 GLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSW 227
           GLFIID  G+++ +++NDLPVGRSV+ETLRLV+AFQY + HGE  P ++W
Sbjct: 185 GLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCP-ANW 233


>gi|32483377 peroxiredoxin 3 isoform b [Homo sapiens]
          Length = 238

 Score =  176 bits (446), Expect = 2e-44
 Identities = 89/169 (52%), Positives = 114/169 (67%), Gaps = 24/169 (14%)

Query: 82  SKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSI 141
           S  APY++GTAV++GEFK+L L D++GKYLV FFYPLDFTFVCPTEI+AF D+  EF  +
Sbjct: 48  SSQAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDV 107

Query: 142 NTEVVACSVDSQFTHLAW-----------------------SVSYTYIRRKKRMDLLLKG 178
           N EVVA SVDS F+HLAW                        +S  Y    +   L L+G
Sbjct: 108 NCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRG 167

Query: 179 LFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSW 227
           LFIID  G+++ +++NDLPVGRSV+ETLRLV+AFQY + HGE  P ++W
Sbjct: 168 LFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCP-ANW 215


>gi|33188454 peroxiredoxin 2 isoform c [Homo sapiens]
          Length = 142

 Score =  127 bits (319), Expect = 8e-30
 Identities = 57/81 (70%), Positives = 69/81 (85%)

Query: 79  AKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEF 138
           A+I KPAP ++ TAV+DG FKE+KL+DY+GKY+V FFYPLDFTFVCPTEIIAF +R E+F
Sbjct: 6   ARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDF 65

Query: 139 RSINTEVVACSVDSQFTHLAW 159
           R +  EV+  SVDSQFTHLAW
Sbjct: 66  RKLGCEVLGVSVDSQFTHLAW 86


>gi|4758638 peroxiredoxin 6 [Homo sapiens]
          Length = 224

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 47/177 (26%), Positives = 72/177 (40%), Gaps = 38/177 (21%)

Query: 85  APYWEGTAVIDGEFKELKLTDYRG-KYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINT 143
           AP +E    +      ++  D+ G  + + F +P DFT VC TE+        EF   N 
Sbjct: 11  APNFEANTTVG----RIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNV 66

Query: 144 EVVACSVDSQFTHLAWS--------------VSYTYIRRKKRMDLLLKGLF---IIDDKG 186
           +++A S+DS   HLAWS              + +  I  + R   +L G+      D+KG
Sbjct: 67  KLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKG 126

Query: 187 I---------------LRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEDNPRSSWK 228
           +               L+   L     GR+ DE LR+V + Q T +     P   WK
Sbjct: 127 MPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATP-VDWK 182


>gi|169205475 PREDICTED: similar to peroxiredoxin 6 [Homo sapiens]
          Length = 137

 Score = 34.7 bits (78), Expect = 0.072
 Identities = 17/49 (34%), Positives = 24/49 (48%)

Query: 112 VFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWS 160
           + F +P D   VC  E+        EF   N +++A + DS   HLAWS
Sbjct: 34  ILFSHPRDSKPVCTMELGRAAKLAPEFTKSNVKLIALATDSAEDHLAWS 82


>gi|186928821 hepatoma-derived growth factor isoform c [Homo
           sapiens]
          Length = 233

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 1/53 (1%)

Query: 90  GTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSIN 142
           G AVID E  E  +     KY VFFF   +  F+ P ++  + +  E+F   N
Sbjct: 19  GAAVID-EMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPN 70


>gi|22748713 ankyrin repeat domain 9 [Homo sapiens]
          Length = 317

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 18/40 (45%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 9   ATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETE---ERPR 45
           A+ P   R RRLLLL LL    P GA      E   +RPR
Sbjct: 218 ASAPGEPRQRRLLLLDLLALYTPVGAAGSARQELLGDRPR 257


>gi|11055992 serine carboxypeptidase 1 precursor [Homo sapiens]
          Length = 452

 Score = 28.9 bits (63), Expect = 3.9
 Identities = 18/25 (72%), Positives = 18/25 (72%), Gaps = 1/25 (4%)

Query: 18 RRLLLLPLLLFLLPAGAVQGWETEE 42
          R LLLLPLLL L  AGAV  W TEE
Sbjct: 12 RWLLLLPLLLGL-NAGAVIDWPTEE 35


>gi|157276599 bactericidal/permeability-increasing protein precursor
           [Homo sapiens]
          Length = 487

 Score = 28.5 bits (62), Expect = 5.2
 Identities = 23/104 (22%), Positives = 42/104 (40%), Gaps = 15/104 (14%)

Query: 89  EGTAVIDGEFKELKLTDYRGKYLV-------FFFYPLDF-TFVCPTEIIAFGDRLEEFRS 140
           +GTA +  E K +K+ DY   + +       + FY +D   F  P+  I+    +    S
Sbjct: 51  QGTAALQKELKRIKIPDYSDSFKIKHLGKGHYSFYSMDIREFQLPSSQISMVPNVGLKFS 110

Query: 141 INTEVVACSVDSQFTHLAWSVSYTYIRRKKRMDLLLKGLFIIDD 184
           I+   +  S         W     +++     DL ++G+ I  D
Sbjct: 111 ISNANIKISG-------KWKAQKRFLKMSGNFDLSIEGMSISAD 147


>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
          Length = 240

 Score = 28.1 bits (61), Expect = 6.7
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 83  KPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSIN 142
           K  P+W   A ID E  E  +     KY VFFF   +  F+ P ++  + +  E+F   N
Sbjct: 21  KGYPHWP--ARID-EMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPN 77


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,174,607
Number of Sequences: 37866
Number of extensions: 386676
Number of successful extensions: 843
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 821
Number of HSP's gapped (non-prelim): 16
length of query: 233
length of database: 18,247,518
effective HSP length: 99
effective length of query: 134
effective length of database: 14,498,784
effective search space: 1942837056
effective search space used: 1942837056
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.