Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 119395758
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
(1272 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 2533 0.0
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 2508 0.0
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 1089 0.0
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 1089 0.0
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens] 949 0.0
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens] 796 0.0
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 396 e-110
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 339 9e-93
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 339 9e-93
gi|160707881 formin 2 [Homo sapiens] 318 2e-86
gi|40548415 dishevelled associated activator of morphogenesis 2 ... 263 8e-70
gi|33356148 formin-like 1 [Homo sapiens] 232 1e-60
gi|157168329 formin 1 [Homo sapiens] 229 1e-59
gi|52485606 formin-like 2 [Homo sapiens] 206 9e-53
gi|145309324 FH2 domain containing 1 [Homo sapiens] 195 3e-49
gi|119120861 formin-like 3 isoform 2 [Homo sapiens] 191 3e-48
gi|119120874 formin-like 3 isoform 1 [Homo sapiens] 191 3e-48
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int... 172 2e-42
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] 144 5e-34
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] 133 9e-31
gi|11386183 WAS protein family, member 2 [Homo sapiens] 118 3e-26
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 118 4e-26
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 117 7e-26
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 116 2e-25
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 112 2e-24
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 111 4e-24
gi|153792074 proline rich 12 [Homo sapiens] 109 2e-23
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 108 3e-23
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 108 4e-23
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 108 4e-23
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 2533 bits (6564), Expect = 0.0
Identities = 1272/1272 (100%), Positives = 1272/1272 (100%)
Query: 1 MEPPGGSLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIKKE 60
MEPPGGSLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIKKE
Sbjct: 1 MEPPGGSLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIKKE 60
Query: 61 KEKPNSAHRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIII 120
KEKPNSAHRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIII
Sbjct: 61 KEKPNSAHRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIII 120
Query: 121 KREMVSQYLYTSKAGMSQKESSKSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWV 180
KREMVSQYLYTSKAGMSQKESSKSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWV
Sbjct: 121 KREMVSQYLYTSKAGMSQKESSKSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWV 180
Query: 181 QTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEG 240
QTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEG
Sbjct: 181 QTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEG 240
Query: 241 ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQPLLD 300
ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQPLLD
Sbjct: 241 ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQPLLD 300
Query: 301 GLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIENEDMRV 360
GLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIENEDMRV
Sbjct: 301 GLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIENEDMRV 360
Query: 361 QLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLV 420
QLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLV
Sbjct: 361 QLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLV 420
Query: 421 RNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAK 480
RNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAK
Sbjct: 421 RNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAK 480
Query: 481 AAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAE 540
AAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAE
Sbjct: 481 AAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAE 540
Query: 541 VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPP 600
VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPP
Sbjct: 541 VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPP 600
Query: 601 APGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 660
APGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG
Sbjct: 601 APGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 660
Query: 661 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL 720
VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL
Sbjct: 661 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL 720
Query: 721 PGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR 780
PGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR
Sbjct: 721 PGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR 780
Query: 781 RPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKS 840
RPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKS
Sbjct: 781 RPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKS 840
Query: 841 VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPE 900
VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPE
Sbjct: 841 VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPE 900
Query: 901 PEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSV 960
PEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSV
Sbjct: 901 PEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSV 960
Query: 961 TAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLL 1020
TAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLL
Sbjct: 961 TAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLL 1020
Query: 1021 HFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAAT 1080
HFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAAT
Sbjct: 1021 HFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAAT 1080
Query: 1081 DEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHN 1140
DEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHN
Sbjct: 1081 DEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHN 1140
Query: 1141 FRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMD 1200
FRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMD
Sbjct: 1141 FRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMD 1200
Query: 1201 SLLEALQSGAAFRRKRGPRQANRKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTI 1260
SLLEALQSGAAFRRKRGPRQANRKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTI
Sbjct: 1201 SLLEALQSGAAFRRKRGPRQANRKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTI 1260
Query: 1261 LEEAKELVGRAS 1272
LEEAKELVGRAS
Sbjct: 1261 LEEAKELVGRAS 1272
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 2508 bits (6501), Expect = 0.0
Identities = 1263/1272 (99%), Positives = 1263/1272 (99%), Gaps = 9/1272 (0%)
Query: 1 MEPPGGSLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFTLKRLMADELERFTSMRIKKE 60
MEPPGGSLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKF LERFTSMRIKKE
Sbjct: 1 MEPPGGSLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKF---------LERFTSMRIKKE 51
Query: 61 KEKPNSAHRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIII 120
KEKPNSAHRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIII
Sbjct: 52 KEKPNSAHRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQPLREKDIII 111
Query: 121 KREMVSQYLYTSKAGMSQKESSKSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWV 180
KREMVSQYLYTSKAGMSQKESSKSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWV
Sbjct: 112 KREMVSQYLYTSKAGMSQKESSKSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNPVSWV 171
Query: 181 QTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEG 240
QTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEG
Sbjct: 172 QTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEG 231
Query: 241 ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQPLLD 300
ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQPLLD
Sbjct: 232 ILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQPLLD 291
Query: 301 GLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIENEDMRV 360
GLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIENEDMRV
Sbjct: 292 GLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIENEDMRV 351
Query: 361 QLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLV 420
QLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLV
Sbjct: 352 QLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLV 411
Query: 421 RNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAK 480
RNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAK
Sbjct: 412 RNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAK 471
Query: 481 AAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAE 540
AAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAE
Sbjct: 472 AAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAE 531
Query: 541 VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPP 600
VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPP
Sbjct: 532 VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPP 591
Query: 601 APGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 660
APGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG
Sbjct: 592 APGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 651
Query: 661 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL 720
VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL
Sbjct: 652 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL 711
Query: 721 PGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR 780
PGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR
Sbjct: 712 PGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR 771
Query: 781 RPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKS 840
RPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKS
Sbjct: 772 RPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKS 831
Query: 841 VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPE 900
VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPE
Sbjct: 832 VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPE 891
Query: 901 PEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSV 960
PEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSV
Sbjct: 892 PEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSV 951
Query: 961 TAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLL 1020
TAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLL
Sbjct: 952 TAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLL 1011
Query: 1021 HFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAAT 1080
HFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAAT
Sbjct: 1012 HFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAAT 1071
Query: 1081 DEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHN 1140
DEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHN
Sbjct: 1072 DEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHN 1131
Query: 1141 FRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMD 1200
FRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMD
Sbjct: 1132 FRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMD 1191
Query: 1201 SLLEALQSGAAFRRKRGPRQANRKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTI 1260
SLLEALQSGAAFRRKRGPRQANRKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTI
Sbjct: 1192 SLLEALQSGAAFRRKRGPRQANRKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTI 1251
Query: 1261 LEEAKELVGRAS 1272
LEEAKELVGRAS
Sbjct: 1252 LEEAKELVGRAS 1263
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 1089 bits (2817), Expect = 0.0
Identities = 614/1252 (49%), Positives = 805/1252 (64%), Gaps = 189/1252 (15%)
Query: 1 MEPPGGSL-GPGRGTRDKKKGRSPDELPSAGGDGGKSKK--------FTLKRLMADELER 51
ME PG + G G G+ + GRS SAG ++ +K L D +R
Sbjct: 1 MEQPGAAASGAGGGSEEPGGGRSNKR--SAGNRAANEEETKNKPKLNIQIKTLADDVRDR 58
Query: 52 FTSMRIKK-EKEKPNSAHR-NSSASYGDDPTAQSLQD-----VSDEQVLVLFEQMLLDMN 104
TS R +KEKP H +S + + P AQ L D +S+++VL LFE+M+ DMN
Sbjct: 59 ITSFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMN 118
Query: 105 LNEEKQQPLREKDIIIKREMVSQYLY-TSKAG---MSQKESSKSAMMYIQELRSGLRDMP 160
LNEEK+ PLR KD KREMV QY+ T+K+G S+ E + S+ Y+ ELRSG+ D
Sbjct: 119 LNEEKKAPLRNKDFTTKREMVVQYISATAKSGGLKNSKHECTLSSQEYVHELRSGISDEK 178
Query: 161 LLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRC 220
LL+CLESLRVSL +NPVSWV FG EGL LLD L++L D+K++ + D +N++++I+C
Sbjct: 179 LLNCLESLRVSLTSNPVSWVNNFGHEGLGLLLDELEKLLDKKQQE--NIDKKNQYKLIQC 236
Query: 221 LKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVL 280
LKAFMNNKFG++ +L E +LLL RA+DP PNMM + K+LSA+CI+ + E++ +++L
Sbjct: 237 LKAFMNNKFGLQRILGDERSLLLLARAIDPKQPNMMTEIVKILSAICIVGE-ENILDKLL 295
Query: 281 EAMTERAEMDEVERFQPLLDGLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMR 340
A+T AE + ERF P+++GL++ + L+V C+Q INAL+T ELDFR+H+R+E +R
Sbjct: 296 GAITTAAERNNRERFSPIVEGLENQEALQLQVACMQFINALVTSPYELDFRIHLRNEFLR 355
Query: 341 LGLHQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNT 400
GL +L DL+E EN+++ +QL VFDE E+D +L RL+DIR EMDD NEV+ +L N
Sbjct: 356 SGLKTMLPDLKEKENDELDIQLKVFDENKEDDLTELSHRLNDIRAEMDDMNEVYHLLYNM 415
Query: 401 VKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRH-LQI 459
+KD+ AE +FLSILQH LL+RNDY RPQYYK+IEEC+SQIVLH +G DPDFK R L I
Sbjct: 416 LKDTAAENYFLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCSGMDPDFKYRQRLDI 475
Query: 460 EIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGE 519
++ LID ++K KVE+SE KAAE KK D E
Sbjct: 476 DLTHLIDSCVNKAKVEESEQKAAEFSKKFDEEF--------------------------- 508
Query: 520 KDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSR 579
T +Q+ +AE+ + ++ +L E++ + + LS+++
Sbjct: 509 ------------TARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSS---------- 546
Query: 580 APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI 639
+PG PP PPLPG +
Sbjct: 547 -------GIPG------------------------PPAAPPLPG---------------V 560
Query: 640 SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 699
PPPP PP PPLP G +P PPPPPLPG IPPPPPP P G
Sbjct: 561 GPPPP-------PPAPPLPGGAPLP-----------PPPPPLPGMMGIPPPPPP-PLLFG 601
Query: 700 IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPA 759
PPPPPPL G PPPPG+ +
Sbjct: 602 GPPPPPPLGG-----------------------------VPPPPGISLN----------- 621
Query: 760 APVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTF 819
LP+G+ KK+YKPEV ++R NWSK+ +LS++CFW +VKED+FEN +LFAKL L F
Sbjct: 622 ---LPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNF 678
Query: 820 SAQTKTSKAKKDQEGGEEKKS-VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVI 878
+ Q K +K+ E EEKK+ KKKVKEL++LD KTAQNLSIFLGS+RMPY++I+NVI
Sbjct: 679 ATQI---KVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVI 735
Query: 879 LEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLN 938
LEVNE +L+E++IQNL+K +PE + L L+ELK+EYDDL E EQFGVVM +V L+PRL+
Sbjct: 736 LEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDDLCEPEQFGVVMSSVKMLQPRLS 795
Query: 939 AILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFG 998
+ILFKL F E + NIKP I++VT ACEEL+KSESF+ LLE+ LLVGNYMN+GSRNA + G
Sbjct: 796 SILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLG 855
Query: 999 FNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKN 1058
F I+FLCK+RDTKS DQK TLLHF+A++CE Y D+LKFP+EL HVE AS+VSA+ L+ N
Sbjct: 856 FKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSN 915
Query: 1059 LDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKEL 1118
L M++QI +ERD++ FP A ++ DKFVEKMTSF K A+EQY KL MH+NM LY+ L
Sbjct: 916 LASMEQQIVHLERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENL 975
Query: 1119 GEYFLFDPKKLSVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLE 1178
GEYF+FD K +S+EEFF DL+NFR +FL+AV+EN KRRE EEK RRAKLAKEKAE+E+LE
Sbjct: 976 GEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAKEKAEQEKLE 1035
Query: 1179 KQQKREQLIDMNAEGDETGVMDSLLEALQSGAAF--RRKRGPRQANRKAGCA 1228
+Q+K++QLID+N EGDETGVMD+LLEALQSGAAF RRKR PR CA
Sbjct: 1036 RQKKKKQLIDINKEGDETGVMDNLLEALQSGAAFRDRRKRIPRNPVVNHPCA 1087
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 1089 bits (2817), Expect = 0.0
Identities = 612/1248 (49%), Positives = 805/1248 (64%), Gaps = 189/1248 (15%)
Query: 1 MEPPGGSL-GPGRGTRDKKKGRSPDELPSAGGDGGKSKK--------FTLKRLMADELER 51
ME PG + G G G+ + GRS SAG ++ +K L D +R
Sbjct: 1 MEQPGAAASGAGGGSEEPGGGRSNKR--SAGNRAANEEETKNKPKLNIQIKTLADDVRDR 58
Query: 52 FTSMRIKK-EKEKPNSAHR-NSSASYGDDPTAQSLQD-----VSDEQVLVLFEQMLLDMN 104
TS R +KEKP H +S + + P AQ L D +S+++VL LFE+M+ DMN
Sbjct: 59 ITSFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMN 118
Query: 105 LNEEKQQPLREKDIIIKREMVSQYLY-TSKAG---MSQKESSKSAMMYIQELRSGLRDMP 160
LNEEK+ PLR KD KREMV QY+ T+K+G S+ E + S+ Y+ ELRSG+ D
Sbjct: 119 LNEEKKAPLRNKDFTTKREMVVQYISATAKSGGLKNSKHECTLSSQEYVHELRSGISDEK 178
Query: 161 LLSCLESLRVSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRC 220
LL+CLESLRVSL +NPVSWV FG EGL LLD L++L D+K++ + D +N++++I+C
Sbjct: 179 LLNCLESLRVSLTSNPVSWVNNFGHEGLGLLLDELEKLLDKKQQE--NIDKKNQYKLIQC 236
Query: 221 LKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVL 280
LKAFMNNKFG++ +L E +LLL RA+DP PNMM + K+LSA+CI+ + E++ +++L
Sbjct: 237 LKAFMNNKFGLQRILGDERSLLLLARAIDPKQPNMMTEIVKILSAICIVGE-ENILDKLL 295
Query: 281 EAMTERAEMDEVERFQPLLDGLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMR 340
A+T AE + ERF P+++GL++ + L+V C+Q INAL+T ELDFR+H+R+E +R
Sbjct: 296 GAITTAAERNNRERFSPIVEGLENQEALQLQVACMQFINALVTSPYELDFRIHLRNEFLR 355
Query: 341 LGLHQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNT 400
GL +L DL+E EN+++ +QL VFDE E+D +L RL+DIR EMDD NEV+ +L N
Sbjct: 356 SGLKTMLPDLKEKENDELDIQLKVFDENKEDDLTELSHRLNDIRAEMDDMNEVYHLLYNM 415
Query: 401 VKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRH-LQI 459
+KD+ AE +FLSILQH LL+RNDY RPQYYK+IEEC+SQIVLH +G DPDFK R L I
Sbjct: 416 LKDTAAENYFLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCSGMDPDFKYRQRLDI 475
Query: 460 EIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGE 519
++ LID ++K KVE+SE KAAE KK D E
Sbjct: 476 DLTHLIDSCVNKAKVEESEQKAAEFSKKFDEEF--------------------------- 508
Query: 520 KDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSR 579
T +Q+ +AE+ + ++ +L E++ + + LS+++
Sbjct: 509 ------------TARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSS---------- 546
Query: 580 APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI 639
+PG PP PPLPG +
Sbjct: 547 -------GIPG------------------------PPAAPPLPG---------------V 560
Query: 640 SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 699
PPPP PP PPLP G +P PPPPPLPG IPPPPPP P G
Sbjct: 561 GPPPP-------PPAPPLPGGAPLP-----------PPPPPLPGMMGIPPPPPP-PLLFG 601
Query: 700 IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPA 759
PPPPPPL G PPPPG+ +
Sbjct: 602 GPPPPPPLGG-----------------------------VPPPPGISLN----------- 621
Query: 760 APVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTF 819
LP+G+ KK+YKPEV ++R NWSK+ +LS++CFW +VKED+FEN +LFAKL L F
Sbjct: 622 ---LPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNF 678
Query: 820 SAQTKTSKAKKDQEGGEEKKS-VQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVI 878
+ Q K +K+ E EEKK+ KKKVKEL++LD KTAQNLSIFLGS+RMPY++I+NVI
Sbjct: 679 ATQI---KVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVI 735
Query: 879 LEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLN 938
LEVNE +L+E++IQNL+K +PE + L L+ELK+EYDDL E EQFGVVM +V L+PRL+
Sbjct: 736 LEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDDLCEPEQFGVVMSSVKMLQPRLS 795
Query: 939 AILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFG 998
+ILFKL F E + NIKP I++VT ACEEL+KSESF+ LLE+ LLVGNYMN+GSRNA + G
Sbjct: 796 SILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLG 855
Query: 999 FNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKN 1058
F I+FLCK+RDTKS DQK TLLHF+A++CE Y D+LKFP+EL HVE AS+VSA+ L+ N
Sbjct: 856 FKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSN 915
Query: 1059 LDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKEL 1118
L M++QI +ERD++ FP A ++ DKFVEKMTSF K A+EQY KL MH+NM LY+ L
Sbjct: 916 LASMEQQIVHLERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENL 975
Query: 1119 GEYFLFDPKKLSVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLE 1178
GEYF+FD K +S+EEFF DL+NFR +FL+AV+EN KRRE EEK RRAKLAKEKAE+E+LE
Sbjct: 976 GEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAKEKAEQEKLE 1035
Query: 1179 KQQKREQLIDMNAEGDETGVMDSLLEALQSGAAF--RRKRGPRQANRK 1224
+Q+K++QLID+N EGDETGVMD+LLEALQSGAAF RRKR PR + +
Sbjct: 1036 RQKKKKQLIDINKEGDETGVMDNLLEALQSGAAFRDRRKRIPRNPDNR 1083
>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
Length = 1193
Score = 949 bits (2452), Expect = 0.0
Identities = 546/1224 (44%), Positives = 750/1224 (61%), Gaps = 185/1224 (15%)
Query: 12 RGTRDKKKGR--SPDELPSAGGD---GGKSKKFTL--KRLMADELERFTSMRIKKEKEKP 64
RG R+ K R P P G G K KF L + L D L++F S+RI K++
Sbjct: 28 RGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKER 87
Query: 65 NSAHRNSSASYGDDPTAQSLQ-------DVSDEQVLVLFEQMLLDMNLNEEKQQPLREKD 117
+A D +A L+ +S+ ++L LFE+M+ DMNLNE+K+ PLREKD
Sbjct: 88 PPLPNLKTAFASSDCSAAPLEMMENFPKPLSENELLELFEKMMEDMNLNEDKKAPLREKD 147
Query: 118 IIIKREMVSQYLYT-SKAGMSQKESSKSAMMYIQELRSGLRDMPLLSCLESLRVSLNNNP 176
IK+EMV QY+ T SK G ++ S +I EL+ G D L++CLESLRVSL +NP
Sbjct: 148 FSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNP 207
Query: 177 VSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLE 236
VSWV++FG EGL LLDIL++L K + +N+H++I+CLKA MN ++G++ ++
Sbjct: 208 VSWVESFGHEGLGLLLDILEKLISGKIQE--KVVKKNQHKVIQCLKALMNTQYGLERIMS 265
Query: 237 TEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVERFQ 296
E + LL +A+DP PNMM D KLLSA+CI+ + E + E VLEA+T E +++RF
Sbjct: 266 EERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGE-ESILEEVLEALTSAGEEKKIDRFF 324
Query: 297 PLLDGLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIENE 356
+++GL+ + + L+V C+QLINAL+T ++LDFR+HIR+E MR GL ++L +L+ I+N+
Sbjct: 325 CIVEGLRHNS-VQLQVACMQLINALVTSPDDLDFRLHIRNEFMRCGLKEILPNLKCIKND 383
Query: 357 DMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQH 416
+ +QL VFDE EED ++L RL+DIR E+D+ +V+ ++ +TVK+++AE +F+SILQH
Sbjct: 384 GLDIQLKVFDEHKEEDLFELSHRLEDIRAELDEAYDVYNMVWSTVKETRAEGYFISILQH 443
Query: 417 LLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEK 476
LLL+RNDY R QY+KLI+EC+SQIVLH++G DPDF R
Sbjct: 444 LLLIRNDYFIRQQYFKLIDECVSQIVLHRDGMDPDFTYR--------------------- 482
Query: 477 SEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQD 536
K+LD +LT ++ ++ K+E +FE+K + L+ + ++ T+ Q+
Sbjct: 483 ---------KRLDLDLTQFVDICIDQAKLE-EFEEKASE-------LYKKFEKEFTDHQE 525
Query: 537 LEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTII 596
+A E+ K ++ + + E+ + + LP D
Sbjct: 526 TQA-------ELQKKEAKINELQAELQAFKSQF----------------GALPADCNI-- 560
Query: 597 PPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPP 656
P PP GG G +A+ PPPPL +PPPPP
Sbjct: 561 -------------------PLPPSKEGGT---------GHSALPPPPPLPSGGGVPPPPP 592
Query: 657 LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP 716
PPPPPLPG +P S +PPP
Sbjct: 593 ------------------PPPPPPLPGMR--------MPFSGPVPPP------------- 613
Query: 717 PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPE 776
PP F GG PP P+LPFGL PKK +KPE
Sbjct: 614 -----------PPLGFLGGQNSPP-------------------LPILPFGLKPKKEFKPE 643
Query: 777 VQLRRPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGE 836
+ +RR NW K+ +++++CFW KV E+++EN +L KL TF Q K ++++E E
Sbjct: 644 ISMRRLNWLKIRPHEMTENCFWIKVNENKYENVDLLCKLENTFCCQ---QKERREEEDIE 700
Query: 837 EKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIK 896
EKKS+ KKK+KELK LDSK AQNLSIFL SFR+PY+EI+ +ILEV+E L ESMIQNLIK
Sbjct: 701 EKKSI-KKKIKELKFLDSKIAQNLSIFLSSFRVPYEEIRMMILEVDETRLAESMIQNLIK 759
Query: 897 QMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPE 956
+P+ EQL LS+ K EY +L E EQF VVM V RLRPRL+AILFKLQF EQV NIKP+
Sbjct: 760 HLPDQEQLNSLSQFKSEYSNLCEPEQFVVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPD 819
Query: 957 IVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQK 1016
I++V+ ACEE++KS+SFS LLE+ LL+GNYMNAGSRNA FGFN+S LCKL+DTKS DQK
Sbjct: 820 IMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFNLSSLCKLKDTKSADQK 879
Query: 1017 MTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNF 1076
TLLHFL E+CE YPD+L F D+L ++KAS+VS E L+KNL QM +Q+ +E++++ F
Sbjct: 880 TTLLHFLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELETF 939
Query: 1077 PAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFM 1136
P D DKFV KM+ FV A+EQY L +H NME LY+ + Y+ D KK+SVE+F
Sbjct: 940 PPPEDLHDKFVTKMSRFVISAKEQYETLSKLHENMEKLYQSIIGYYAIDVKKVSVEDFLT 999
Query: 1137 DLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDET 1196
DL+NFR F+QA+KEN K+RE EEK +R ++AKE AE+ERLE+QQK+++L++M EGDET
Sbjct: 1000 DLNNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAERERLERQQKKKRLLEMKTEGDET 1059
Query: 1197 GVMDSLLEALQSGAAF--RRKRGP 1218
GVMD+LLEALQSGAAF RRKR P
Sbjct: 1060 GVMDNLLEALQSGAAFRDRRKRTP 1083
>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
Length = 849
Score = 796 bits (2055), Expect = 0.0
Identities = 447/986 (45%), Positives = 609/986 (61%), Gaps = 168/986 (17%)
Query: 235 LETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEMDEVER 294
+ E + LL +A+DP PNMM D KLLSA+CI+ + E + E VLEA+T E +++R
Sbjct: 1 MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGE-ESILEEVLEALTSAGEEKKIDR 59
Query: 295 FQPLLDGLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIE 354
F +++GL+ + + L+V C+QLINAL+T ++LDFR+HIR+E MR GL ++L +L+ I+
Sbjct: 60 FFCIVEGLRHNS-VQLQVACMQLINALVTSPDDLDFRLHIRNEFMRCGLKEILPNLKCIK 118
Query: 355 NEDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSIL 414
N+ + +QL VFDE EED ++L RL+DIR E+D+ +V+ ++ +TVK+++AE +F+SIL
Sbjct: 119 NDGLDIQLKVFDEHKEEDLFELSHRLEDIRAELDEAYDVYNMVWSTVKETRAEGYFISIL 178
Query: 415 QHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKV 474
QHLLL+RNDY R QY+KLI+EC+SQIVLH++G DPDF R
Sbjct: 179 QHLLLIRNDYFIRQQYFKLIDECVSQIVLHRDGMDPDFTYR------------------- 219
Query: 475 EKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEK 534
K+LD +LT ++ ++ K+E +FE+K + L+ + ++ T+
Sbjct: 220 -----------KRLDLDLTQFVDICIDQAKLE-EFEEKASE-------LYKKFEKEFTDH 260
Query: 535 QDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGT 594
Q+ +A E+ K ++ + + E+ + + LP D
Sbjct: 261 QETQA-------ELQKKEAKINELQAELQAFKSQF----------------GALPADCNI 297
Query: 595 IIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP 654
P PP GG G +A+ PPPPL +PPP
Sbjct: 298 ---------------------PLPPSKEGGT---------GHSALPPPPPLPSGGGVPPP 327
Query: 655 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP 714
PP PPPPPLPG +P S +PPP
Sbjct: 328 PP------------------PPPPPPLPGMR--------MPFSGPVPPP----------- 350
Query: 715 PPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYK 774
PP F GG PP P+LPFGL PKK +K
Sbjct: 351 -------------PPLGFLGGQNSPP-------------------LPILPFGLKPKKEFK 378
Query: 775 PEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEG 834
PE+ +RR NW K+ +++++CFW KV E+++EN +L KL TF Q K ++++E
Sbjct: 379 PEISMRRLNWLKIRPHEMTENCFWIKVNENKYENVDLLCKLENTFCCQ---QKERREEED 435
Query: 835 GEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNL 894
EEKKS+ KKK+KELK LDSK AQNLSIFL SFR+PY+EI+ +ILEV+E L ESMIQNL
Sbjct: 436 IEEKKSI-KKKIKELKFLDSKIAQNLSIFLSSFRVPYEEIRMMILEVDETRLAESMIQNL 494
Query: 895 IKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIK 954
IK +P+ EQL LS+ K EY +L E EQF VVM V RLRPRL+AILFKLQF EQV NIK
Sbjct: 495 IKHLPDQEQLNSLSQFKSEYSNLCEPEQFVVVMSNVKRLRPRLSAILFKLQFEEQVNNIK 554
Query: 955 PEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTD 1014
P+I++V+ ACEE++KS+SFS LLE+ LL+GNYMNAGSRNA FGFN+S LCKL+DTKS D
Sbjct: 555 PDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFNLSSLCKLKDTKSAD 614
Query: 1015 QKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQ 1074
QK TLLHFL E+CE YPD+L F D+L ++KAS+VS E L+KNL QM +Q+ +E++++
Sbjct: 615 QKTTLLHFLVEICEEKYPDILNFVDDLEPLDKASKVSVETLEKNLRQMGRQLQQLEKELE 674
Query: 1075 NFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEF 1134
FP D DKFV KM+ FV A+EQY L +H NME LY+ + Y+ D KK+SVE+F
Sbjct: 675 TFPPPEDLHDKFVTKMSRFVISAKEQYETLSKLHENMEKLYQSIIGYYAIDVKKVSVEDF 734
Query: 1135 FMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGD 1194
DL+NFR F+QA+KEN K+RE EEK +R ++AKE AE+ERLE+QQK+++L++M EGD
Sbjct: 735 LTDLNNFRTTFMQAIKENIKKREAEEKEKRVRIAKELAERERLERQQKKKRLLEMKTEGD 794
Query: 1195 ETGVMDSLLEALQSGAAF--RRKRGP 1218
ETGVMD+LLEALQSGAAF RRKR P
Sbjct: 795 ETGVMDNLLEALQSGAAFRDRRKRTP 820
>gi|21071077 dishevelled-associated activator of morphogenesis 1 [Homo
sapiens]
Length = 1078
Score = 396 bits (1018), Expect = e-110
Identities = 320/1170 (27%), Positives = 548/1170 (46%), Gaps = 197/1170 (16%)
Query: 90 EQVLVLFEQMLLDMNLNEEKQQPLREKDIIIKREMVSQYLYTSKAGMSQKESSKS-AMMY 148
E++ V+F +++ +++L ++ RE + E Q + K + + + S Y
Sbjct: 51 EELDVMFSELVDELDLTDKH----REAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFY 106
Query: 149 IQELRSGLRDMPLLSC-----------LESLRVSLNNNPVSWVQTF-GAEGLASLLDILK 196
I +L S LL+ +ESL+ +L P+ +V F +GL+ +L+ LK
Sbjct: 107 IDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLK 166
Query: 197 RLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMM 256
+ E E SR +I C+KA MNN G +L E I ++ +++
Sbjct: 167 TMDYETSE------SRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTK 220
Query: 257 IDAAKLLSALCILPQPEDMNERVLEAMTERAEM-DEVERFQPLLDGLKSGT-----TIAL 310
+ ++L A+C++P +++VL+AM + E RFQ L++ L T ++L
Sbjct: 221 VAVLEILGAVCLVPGG---HKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSL 277
Query: 311 KVGCLQLINALITPA---EELDFRVHIRSELMRLGLHQVLQDLREIENEDMRVQLNVFDE 367
K + INA+++ E LDFR+H+R E + LG+ V+ LRE EN + L+ F+
Sbjct: 278 KTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEM 337
Query: 368 QGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEAR 427
ED + R + + ++ ++F++ + S+A PHF+SIL H L +
Sbjct: 338 LRNEDELEFAKRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGN 397
Query: 428 P-QYYKLIEECISQIVLHKN-GADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELE 485
QY+ L++ I QIV+ + G DPD I+ ++ ++++ +V++ + +A ++
Sbjct: 398 TVQYWLLLDRIIQQIVIQNDKGQDPDSTPLE-NFNIKNVVRMLVNENEVKQWKEQAEKMR 456
Query: 486 KKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLT 545
K+ +ELQ +++K E + + K Q+ + L+ K+++ E E Q+
Sbjct: 457 KE-------HNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKET----TEHKQVK 505
Query: 546 GEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDS 605
+VA LT +L + + S IP P+PG
Sbjct: 506 QQVADLTAQLHELSRRAVCAS-----------------------------IPGGPSPG-- 534
Query: 606 TTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS 665
PGG P S+PG + +PPPP
Sbjct: 535 ---------------APGG---PFPSSVPG-------------SLLPPPP---------- 553
Query: 666 PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 725
PPPLPG +PPPPPPLP P PPP PP PPPL
Sbjct: 554 ------------PPPLPG-GMLPPPPPPLP-----PGGPPP-------PPGPPPL----- 583
Query: 726 IPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWS 785
G +PPP MG+ L K + +P L+ NWS
Sbjct: 584 ---------GAIMPPPGAPMGL------------------ALKKKSIPQPTNALKSFNWS 616
Query: 786 KLVAEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTK------TSKAKKDQEGGEEKK 839
KL E+ + WT++ + + L TFSA + S +K+ + +
Sbjct: 617 KL-PENKLEGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQDFFVNSNSKQKEADAIDDT 675
Query: 840 SVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAV-LTESMIQNLIKQM 898
K KVKEL V+D + AQN +I L ++ EIK IL ++E L + M++ L+K +
Sbjct: 676 LSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFV 735
Query: 899 PEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIV 958
PE + +L E K E D +A++++F M + + RL ++ FK +F+E+V +KP++
Sbjct: 736 PEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVE 795
Query: 959 SVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKST-DQKM 1017
++ + EE+ +S + LLE+ L GNYMN G R A+GF IS L K+ DTKS+ D+ +
Sbjct: 796 AIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQR-GNAYGFKISSLNKIADTKSSIDKNI 854
Query: 1018 TLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFP 1077
TLLH+L + EN YP VL +EL + +A++V+ L K + ++ + VE +++
Sbjct: 855 TLLHYLITIVENKYPSVLNLNEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQK 914
Query: 1078 AATDEK-DKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFM 1136
+ + DKFV ++ F+ A ++ + + + + L+ + ++F + K+ +EFF
Sbjct: 915 SQPPQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGEEAGKIQPDEFFG 974
Query: 1137 DLHNFRNMFLQAVKENQK-RRETEEKMRRAKL-AKEKAEKERLEKQQKREQLIDMNAEGD 1194
F +A +EN+ R++ EE+ RRA++ A+ K ++ER K +K ++ +
Sbjct: 975 IFDQFLQAVSEAKQENENMRKKKEEEERRARMEAQLKEQRERERKMRKAKE------NSE 1028
Query: 1195 ETGVMDSLLEALQSGAAFRRKRGPRQANRK 1224
E+G D L+ AL+SG F + + NRK
Sbjct: 1029 ESGEFDDLVSALRSGEVFDKDLSKLKRNRK 1058
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 339 bits (870), Expect = 9e-93
Identities = 302/1095 (27%), Positives = 497/1095 (45%), Gaps = 148/1095 (13%)
Query: 151 ELRSGLRDMPLLSCLESLRVSLNNNPVSW-VQTFGAEGLASLLDILKRLHDEKEETAGSY 209
EL L MP + LR L + W VQ GL LL+ L RL A
Sbjct: 36 ELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALARLSGRG--VARIS 93
Query: 210 DSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCIL 269
D+ + + C++A MN++ GI+ +L + + L +A+D + + +LL+ALCI
Sbjct: 94 DALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIY 153
Query: 270 PQPEDMNERVLEAMTE-RAEMDEVERFQPLLDGLKSGTTIALKVGCLQLINALITPAEEL 328
PE + L+A+ + + RF +++ L + V L +INA+I E+L
Sbjct: 154 -SPEG-HVLTLDALDHYKTVCSQQYRFSIVMNELSGSDNVPYVVTLLSVINAVILGPEDL 211
Query: 329 DFRVHIRSELMRLGLHQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMD 388
R +R+E + L L VL LR++E+ D+ +QL F+E ED +L + +M
Sbjct: 212 RARTQLRNEFIGLQLLDVLARLRDLEDADLLIQLEAFEEAKAEDEEELLRVSGGV--DMS 269
Query: 389 DFNEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGA 448
EVF L + V S LS + Q +LH
Sbjct: 270 SHQEVFASLFHKVSCSPVSAQLLS-------------------------VLQGLLH---L 301
Query: 449 DPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESD 508
+P + L E ++ ++++ + S+A+ LE+ ++ L+ V+ + S
Sbjct: 302 EPTLRSSQLLWEA---LESLVNRAVLLASDAQECTLEEVVERLLS------VKGRPRPSP 352
Query: 509 FEQKLQDLQGEKDALH--SEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLS 566
+ + +Q D S Q T K +E + A + ++ A+ E S
Sbjct: 353 LVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPA----AAAACEPVDHAQSE----S 404
Query: 567 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 626
++ P ++ +A +TPPPPPPPP
Sbjct: 405 ILKVSQPRALEQQA-------------------------STPPPPPPPP----------- 428
Query: 627 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 686
LPG +A PPPP PPPPLP VG +LP PPPPPLPG
Sbjct: 429 -----LLPGSSAEPPPPP--------PPPPLPS-VGA---KALP---TAPPPPPLPGLGA 468
Query: 687 IPPP----PPPLPGSAG-IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP 741
+ PP PPPLPGS +PPPPPPLPG PPPPP LPG PPPPP P P P
Sbjct: 469 MAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528
Query: 742 PPGMGMPP----PPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQ-DC 796
P GM G G P + +++ P +++++ NW KL + + +
Sbjct: 529 PVAGGMEEVIVAQVDHGLGSAWVP------SHRRVNPPTLRMKKLNWQKLPSNVAREHNS 582
Query: 797 FWTKVKEDRFENNEL-FAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSK 855
W + E E F+ + FS AK + ++ +K+ KE+ LD+K
Sbjct: 583 MWASLSSPDAEAVEPDFSSIERLFSFPA----AKPKEPTMVAPRA--RKEPKEITFLDAK 636
Query: 856 TAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYD 915
+ NL+IFL F+ +E+ +I + +++ L+K +PE +++ L +E
Sbjct: 637 KSLNLNIFLKQFKCSNEEVAAMIRAGDTTKFDVEVLKQLLKLLPEKHEIENLRAFTEERA 696
Query: 916 DLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSN 975
LA ++ F +++ +P + R+ +L + ++ ++P+ V AACE L S
Sbjct: 697 KLASADHFYLLLLAIPCYQLRIECMLLCEGAAAVLDMVRPKAQLVLAACESLLTSRQLPI 756
Query: 976 LLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVL 1035
++ L +GN++N GS A GF IS L KL +TKS ++TLLH + E E +PD+L
Sbjct: 757 FCQLILRIGNFLNYGSHTGDADGFKISTLLKLTETKSQQNRVTLLHHVLEEAEKSHPDLL 816
Query: 1036 KFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVK 1095
+ P +L +A+ ++ E ++ K++ + ER V + + ++++ E++ + +
Sbjct: 817 QLPRDLEQPSQAAGINLEIIRSEASSNLKKLLETERKVS--ASVAEVQEQYTERLQASI- 873
Query: 1096 DAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNFRNMFLQAVKENQKR 1155
+ L + +E +EL +Y D ++LS+E+ F + FR++FL+A+KEN+ R
Sbjct: 874 ---SAFRALDELFEAIEQKQRELADYLCEDAQQLSLEDTFSTMKAFRDLFLRALKENKDR 930
Query: 1156 RETEEKMRRAK--LAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFR 1213
+E K R K LA+E+A + R E + + + +E V+D+LL ++ G R
Sbjct: 931 KEQAAKAERRKQQLAEEEARRPRGEDGKPVRK---GPGKQEEVCVIDALLADIRKGFQLR 987
Query: 1214 ---RKRGPRQANRKA 1225
R RG KA
Sbjct: 988 KTARGRGDTDGGSKA 1002
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 339 bits (870), Expect = 9e-93
Identities = 302/1095 (27%), Positives = 497/1095 (45%), Gaps = 148/1095 (13%)
Query: 151 ELRSGLRDMPLLSCLESLRVSLNNNPVSW-VQTFGAEGLASLLDILKRLHDEKEETAGSY 209
EL L MP + LR L + W VQ GL LL+ L RL A
Sbjct: 36 ELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALARLSGRG--VARIS 93
Query: 210 DSRNKHEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCIL 269
D+ + + C++A MN++ GI+ +L + + L +A+D + + +LL+ALCI
Sbjct: 94 DALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIY 153
Query: 270 PQPEDMNERVLEAMTE-RAEMDEVERFQPLLDGLKSGTTIALKVGCLQLINALITPAEEL 328
PE + L+A+ + + RF +++ L + V L +INA+I E+L
Sbjct: 154 -SPEG-HVLTLDALDHYKTVCSQQYRFSIVMNELSGSDNVPYVVTLLSVINAVILGPEDL 211
Query: 329 DFRVHIRSELMRLGLHQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMD 388
R +R+E + L L VL LR++E+ D+ +QL F+E ED +L + +M
Sbjct: 212 RARTQLRNEFIGLQLLDVLARLRDLEDADLLIQLEAFEEAKAEDEEELLRVSGGV--DMS 269
Query: 389 DFNEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGA 448
EVF L + V S LS + Q +LH
Sbjct: 270 SHQEVFASLFHKVSCSPVSAQLLS-------------------------VLQGLLH---L 301
Query: 449 DPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESD 508
+P + L E ++ ++++ + S+A+ LE+ ++ L+ V+ + S
Sbjct: 302 EPTLRSSQLLWEA---LESLVNRAVLLASDAQECTLEEVVERLLS------VKGRPRPSP 352
Query: 509 FEQKLQDLQGEKDALH--SEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLS 566
+ + +Q D S Q T K +E + A + ++ A+ E S
Sbjct: 353 LVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPA----AAAACEPVDHAQSE----S 404
Query: 567 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 626
++ P ++ +A +TPPPPPPPP
Sbjct: 405 ILKVSQPRALEQQA-------------------------STPPPPPPPP----------- 428
Query: 627 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 686
LPG +A PPPP PPPPLP VG +LP PPPPPLPG
Sbjct: 429 -----LLPGSSAEPPPPP--------PPPPLPS-VGA---KALP---TAPPPPPLPGLGA 468
Query: 687 IPPP----PPPLPGSAG-IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP 741
+ PP PPPLPGS +PPPPPPLPG PPPPP LPG PPPPP P P P
Sbjct: 469 MAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528
Query: 742 PPGMGMPP----PPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQ-DC 796
P GM G G P + +++ P +++++ NW KL + + +
Sbjct: 529 PVAGGMEEVIVAQVDHGLGSAWVP------SHRRVNPPTLRMKKLNWQKLPSNVAREHNS 582
Query: 797 FWTKVKEDRFENNEL-FAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSK 855
W + E E F+ + FS AK + ++ +K+ KE+ LD+K
Sbjct: 583 MWASLSSPDAEAVEPDFSSIERLFSFPA----AKPKEPTMVAPRA--RKEPKEITFLDAK 636
Query: 856 TAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYD 915
+ NL+IFL F+ +E+ +I + +++ L+K +PE +++ L +E
Sbjct: 637 KSLNLNIFLKQFKCSNEEVAAMIRAGDTTKFDVEVLKQLLKLLPEKHEIENLRAFTEERA 696
Query: 916 DLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSN 975
LA ++ F +++ +P + R+ +L + ++ ++P+ V AACE L S
Sbjct: 697 KLASADHFYLLLLAIPCYQLRIECMLLCEGAAAVLDMVRPKAQLVLAACESLLTSRQLPI 756
Query: 976 LLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVL 1035
++ L +GN++N GS A GF IS L KL +TKS ++TLLH + E E +PD+L
Sbjct: 757 FCQLILRIGNFLNYGSHTGDADGFKISTLLKLTETKSQQNRVTLLHHVLEEAEKSHPDLL 816
Query: 1036 KFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVK 1095
+ P +L +A+ ++ E ++ K++ + ER V + + ++++ E++ + +
Sbjct: 817 QLPRDLEQPSQAAGINLEIIRSEASSNLKKLLETERKVS--ASVAEVQEQYTERLQASI- 873
Query: 1096 DAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNFRNMFLQAVKENQKR 1155
+ L + +E +EL +Y D ++LS+E+ F + FR++FL+A+KEN+ R
Sbjct: 874 ---SAFRALDELFEAIEQKQRELADYLCEDAQQLSLEDTFSTMKAFRDLFLRALKENKDR 930
Query: 1156 RETEEKMRRAK--LAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFR 1213
+E K R K LA+E+A + R E + + + +E V+D+LL ++ G R
Sbjct: 931 KEQAAKAERRKQQLAEEEARRPRGEDGKPVRK---GPGKQEEVCVIDALLADIRKGFQLR 987
Query: 1214 ---RKRGPRQANRKA 1225
R RG KA
Sbjct: 988 KTARGRGDTDGGSKA 1002
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 318 bits (816), Expect = 2e-86
Identities = 244/693 (35%), Positives = 339/693 (48%), Gaps = 120/693 (17%)
Query: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPP-------PPPP-- 615
L A I PP +P A +PP PPLPG I PPPP PG PPPP PPPP
Sbjct: 1036 LPGAGIPPPPPLPG-AGIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1092
Query: 616 ----PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 671
PPPPPLPG V I PP LPG I PPPPL G A IPPPPPLP G GIP P LP
Sbjct: 1093 GAGIPPPPPLPG-VGIPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP- 1147
Query: 672 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 731
IPPPPPLPG+ PPPPPLPG AGI PPPPPLPG G+ PPPPPLP G GIPPPPP
Sbjct: 1148 RVGIPPPPPLPGAG--IPPPPPLPG-AGI-PPPPPLPG-VGI-PPPPPLP-GVGIPPPPP 1200
Query: 732 FPGGPGIPPPP--PGMGMPPP-----PPFGFGVPAAPVLP-------------------- 764
PG GIPPPP PGMG+PP PP G G+P P+LP
Sbjct: 1201 LPGA-GIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259
Query: 765 ------------FGL-------TPKKLYKPEVQLRRPNWSKL---VAEDLSQDCFWTKVK 802
FGL + K+ +P ++ W+++ D S W K++
Sbjct: 1260 CGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIE 1319
Query: 803 E---DRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKE-LKVLDSKTAQ 858
E D E ELF+K T + KK ++ K K K+ +K+L +K +Q
Sbjct: 1320 EPSIDCHEFEELFSK--------TAVKERKK-----PISDTISKTKAKQVVKLLSNKRSQ 1366
Query: 859 NLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKML------SELKD 912
+ I + S + ++I++ ++ ++ +V+ +Q L + + ++L+ + S+ K+
Sbjct: 1367 AVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKE 1426
Query: 913 EYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSES 972
L + EQF + +P R+ ILF+ FSE + +I+ ++ + CE L+
Sbjct: 1427 NAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPG 1486
Query: 973 FSNLLEITLLVGNYMNAGSRNAG-AFGFNISFLCKLRDTKSTDQKMTLL-----HFLAEL 1026
+L + L GNYMN G++ G A GF + L KL+D KS+D +LL ++L
Sbjct: 1487 VMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNF 1546
Query: 1027 CENDYPDVLKFP-DELAHVEKASRVSAENLQKNLDQMKKQIS--DVERDVQNFPAATDEK 1083
E+ + FP E + +AS++ E+ QK+L ++KK + +VE ++ +
Sbjct: 1547 DEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSKEHM 1606
Query: 1084 DKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDP----KKLSVEEFFMDLH 1139
F E M F+ A+ + + E YF P K++S FF H
Sbjct: 1607 QPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEVSPNAFFSIWH 1666
Query: 1140 NFRNMFLQAVKENQKR------RETEEKMRRAK 1166
F + F K+ K +E EE R+ K
Sbjct: 1667 EFSSDFKDFWKKENKLLLQERVKEAEEVCRQKK 1699
Score = 224 bits (572), Expect = 3e-58
Identities = 133/211 (63%), Positives = 141/211 (66%), Gaps = 22/211 (10%)
Query: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPPLP 622
L A I +PP +P A +PP PPLPG I PPPP PG PPPP P PPPPPLP
Sbjct: 959 LPGAGIPLPPPLPG-AGIPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015
Query: 623 GGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLP 682
G I PP LPG I PPPPL G A IPPPPPLP G GIP P LP G IPPPPPLP
Sbjct: 1016 GAG-IPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP-GAGIPPPPPLP 1070
Query: 683 GSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP 742
G+ PPPPPLPG AGI PPPPPLPG AG+ PPPPPLP G GIPPPPP PG GIPPPP
Sbjct: 1071 GAG--IPPPPPLPG-AGI-PPPPPLPG-AGI-PPPPPLP-GVGIPPPPPLPGA-GIPPPP 1122
Query: 743 --PGMGMPPPPPF-GFGVPAAPVLP-FGLTP 769
PG G+PPPPP G G+P P LP G+ P
Sbjct: 1123 PLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
Score = 223 bits (567), Expect = 1e-57
Identities = 138/235 (58%), Positives = 145/235 (61%), Gaps = 34/235 (14%)
Query: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIP-PPPAPGDSTTPPPP-------PPPP- 615
L A I PP +P A +PP PPLPG IP PPP PG PPPP PPPP
Sbjct: 937 LPGAGIPPPPPLPGAA-IPPPPPLPGAG---IPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992
Query: 616 -----PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 670
PPPPPLPG I PP LPG I PPPPL G A IPPPPPLP G GIP P LP
Sbjct: 993 PGAGIPPPPPLPGAG-IPPPPPLPGA-GIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP 1048
Query: 671 GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP 730
G IPPPPPLPG+ PPPPPLPG AGIPPPPP LPG AG+PPPPP LPG GIPPPP
Sbjct: 1049 GA-GIPPPPPLPGAGI--PPPPPLPG-AGIPPPPP-LPG-AGIPPPPP-LPGA-GIPPPP 1100
Query: 731 PFPGGPGIPPPPP--GMGMPPPPPF-GFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782
P PG GIPPPPP G G+PPPPP G G+P P LP P P V + P
Sbjct: 1101 PLPG-VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154
Score = 219 bits (557), Expect = 2e-56
Identities = 131/215 (60%), Positives = 139/215 (64%), Gaps = 21/215 (9%)
Query: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP--PPPPPLPGGVCISSP 630
PP +P A +PP PPLPG I+P PP PG PPPP P PPPPPLP G I P
Sbjct: 912 PPPLPG-AGIPPPPPLPG--AGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP-GAGIPLP 967
Query: 631 PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 690
P LP G I PPPPL G A IPPPPPLP G GIP P LP G IPPPPPLPG+ PP
Sbjct: 968 PPLP-GAGIPPPPPLPG-AGIPPPPPLP-GAGIPPPPPLP-GAGIPPPPPLPGAG--IPP 1021
Query: 691 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP--PGMGMP 748
PPPLPG AGI PPPPPLPG AG+ PPPPPLPG GIPPPPP PG GIPPPP PG G+P
Sbjct: 1022 PPPLPG-AGI-PPPPPLPG-AGI-PPPPPLPGA-GIPPPPPLPGA-GIPPPPPLPGAGIP 1075
Query: 749 PPPPF-GFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782
PPPP G G+P P LP P P V + P
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1110
Score = 212 bits (539), Expect = 2e-54
Identities = 126/215 (58%), Positives = 132/215 (61%), Gaps = 44/215 (20%)
Query: 583 PPAPPLPGDSGTIIP------PPPAPGDSTTPPPPPPPP----PPPPPLPG--------- 623
PP PPLPG + +P PPP G PPPPPP P PPPPPLPG
Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPL 937
Query: 624 -GVCISSPPSLPGGTAISPPPPLSG----------DATIPPPPPLPEGVGIPSPSSLPGG 672
G I PP LPG AI PPPPL G A IPPPPPLP G GIP P LP G
Sbjct: 938 PGAGIPPPPPLPGA-AIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP-GAGIPPPPPLP-G 994
Query: 673 TAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPF 732
IPPPPPLPG+ PPPPPLPG AGI PPPPPLPG AG+ PPPPPLPG GIPPPPP
Sbjct: 995 AGIPPPPPLPGAG--IPPPPPLPG-AGI-PPPPPLPG-AGI-PPPPPLPGA-GIPPPPPL 1047
Query: 733 PGGPGIPPPP--PGMGMPPPPPF-GFGVPAAPVLP 764
PG GIPPPP PG G+PPPPP G G+P P LP
Sbjct: 1048 PGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1081
Score = 204 bits (519), Expect = 4e-52
Identities = 125/218 (57%), Positives = 134/218 (61%), Gaps = 40/218 (18%)
Query: 575 SVPSRAPVP---PAPPLPGDSGTIIPPPPAPG------DSTTPPPPPP------PPPPPP 619
++PS P+P + +PG PPPP PG ST P PPP PPPPP
Sbjct: 854 NIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP 913
Query: 620 PLPGGVCISSPPSLPG----------GTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 669
PLP G I PP LPG G I PPPPL G A IPPPPPLP G GIP P L
Sbjct: 914 PLP-GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPG-AAIPPPPPLP-GAGIPLPPPL 970
Query: 670 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPP 729
P G IPPPPPLPG+ PPPPPLPG AGI PPPPPLPG AG+ PPPPPLPG GIPPP
Sbjct: 971 P-GAGIPPPPPLPGAG--IPPPPPLPG-AGI-PPPPPLPG-AGI-PPPPPLPGA-GIPPP 1022
Query: 730 PPFPGGPGIPPPP--PGMGMPPPPPF-GFGVPAAPVLP 764
PP PG GIPPPP PG G+PPPPP G G+P P LP
Sbjct: 1023 PPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1059
Score = 160 bits (405), Expect = 7e-39
Identities = 135/416 (32%), Positives = 165/416 (39%), Gaps = 137/416 (32%)
Query: 479 AKAAELEKKLDSELTARHELQVEMKKMESDFEQK-LQDLQGEKDA-----LHSEKQQIAT 532
+K + E +L+ T E + SD QK + D++ E A L + + T
Sbjct: 629 SKPPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRT 688
Query: 533 EKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPL---P 589
+ +LE + L EVA + LE+ + A+ + + A + P
Sbjct: 689 KIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSP 748
Query: 590 GDSGTIIPPPPAPGDSTTPPPPP------------------------------------P 613
+ G ++ PP G PP PP
Sbjct: 749 TEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSIS 808
Query: 614 PPPPPPPL--------PGG----------------------------------VCISSPP 631
PPPPP L PG C S
Sbjct: 809 QPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSS 868
Query: 632 SLPGGTAISP--------------------PPPLSGDATIPPPPPLPEGVGIPSPSSLPG 671
S+PG + P PPPL G +PPPPP G GIP P LPG
Sbjct: 869 SMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPG 928
Query: 672 ----------GTAIPPPPPLPGSARIPPPPPPLPGSAGIP----------PPPPPLPGEA 711
G IPPPPPLPG+A PPPPPLPG AGIP PPPPPLPG A
Sbjct: 929 AGILPLPPLPGAGIPPPPPLPGAA--IPPPPPLPG-AGIPLPPPLPGAGIPPPPPLPG-A 984
Query: 712 GMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP--PGMGMPPPPPF-GFGVPAAPVLP 764
G+ PPPPPLPG GIPPPPP PG GIPPPP PG G+PPPPP G G+P P LP
Sbjct: 985 GI-PPPPPLPGA-GIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037
Score = 44.3 bits (103), Expect = 8e-04
Identities = 54/217 (24%), Positives = 73/217 (33%), Gaps = 30/217 (13%)
Query: 531 ATEKQDLEAEVSQLTG----EVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA- 585
ATE++DL +++ Q + +L +L+ +++ A PP+ S P P A
Sbjct: 189 ATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVS--PQPGAF 246
Query: 586 ----PPLPGDSGTIIPPPPAP---------GDSTTPPPPPPPPPPPPPLPGGVCISSPPS 632
L G SG P +P D P P PP PGG+ +S PS
Sbjct: 247 LGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPS 306
Query: 633 LPGGTAISPPPPLSGDATIPPPPPLPEGVGIP------SPSSLPGGTAIPPPPPLPGSAR 686
LP + P S P P E G P + P PG
Sbjct: 307 LPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEW 366
Query: 687 IPPPPPPLPGSAGIPPPP----PPLPGEAGMPPPPPP 719
P P G P P P A +P P P
Sbjct: 367 APEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
Score = 30.8 bits (68), Expect = 8.6
Identities = 29/111 (26%), Positives = 36/111 (32%), Gaps = 15/111 (13%)
Query: 662 GIPSPSSLPGGTAIPPPP------------PLPGSARIPPPPPPLPGSAGIPPPPPPLPG 709
G P++ P TA+ P P P G+ P P + + P L
Sbjct: 228 GAEEPAAPP--TAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAA 285
Query: 710 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAA 760
E P PP PGG + P P P P P G G AA
Sbjct: 286 EP-REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAA 335
>gi|40548415 dishevelled associated activator of morphogenesis 2 [Homo
sapiens]
Length = 1067
Score = 263 bits (672), Expect = 8e-70
Identities = 178/568 (31%), Positives = 294/568 (51%), Gaps = 40/568 (7%)
Query: 688 PPPPPPLPGSAG-----IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP 742
PPP PL S+ +PPPPPPLP PPPPPPLP PG PP PP PP
Sbjct: 523 PPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLP--PGGPPTPPGA------PPC 574
Query: 743 PGMGMP-PPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKV 801
GMG+P P P+ P L K++ +P L+ NW KL E+ W ++
Sbjct: 575 LGMGLPLPQDPY-------PSSDVPLRKKRVPQPSHPLKSFNWVKL-NEERVPGTVWNEI 626
Query: 802 KED---RFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQ 858
+ R + E F K+ FSA + K + G E + +KVKEL V+D + AQ
Sbjct: 627 DDMQVFRILDLEDFEKM---FSAYQRHQK----ELGSTEDIYLASRKVKELSVIDGRRAQ 679
Query: 859 NLSIFLGSFRMPYQEIKNVILEVNEAV-LTESMIQNLIKQMPEPEQLKMLSELKDEYDDL 917
N I L ++ +EI+ IL+++E L + M++ L+K +PE + +L E K E + +
Sbjct: 680 NCIILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERM 739
Query: 918 AESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLL 977
A +++F M + + RL A+ FK +F E++ KP++ ++ A EL +S+ +L
Sbjct: 740 ARADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQML 799
Query: 978 EITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKST-DQKMTLLHFLAELCENDYPDVLK 1036
E+ L +GN+MN G R GA+GF ++ L K+ DTKS+ D+ ++LLH+L + E +PD+L
Sbjct: 800 EVILAIGNFMNKGQR-GGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILN 858
Query: 1037 FPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKD 1096
P EL H+ +A++V+ L+K + +++ + VE + DKFV M+ F+
Sbjct: 859 MPSELQHLPEAAKVNLAELEKEVGNLRRGLRAVEVLEYQRRQVREPSDKFVPVMSDFITV 918
Query: 1097 AQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNFRNMFLQAVKE-NQKR 1155
+ +++L + + + +F K+ +EFF F F +A ++ R
Sbjct: 919 SSFSFSELEDQLNEARDKFAKALMHFGEHDSKMQPDEFFGIFDTFLQAFSEARQDLEAMR 978
Query: 1156 RETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRK 1215
R EE+ RRA++ E+ E+ Q++ +++ + +E G D L+ AL+SG F +
Sbjct: 979 RRKEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALRSGEVFDKD 1038
Query: 1216 RGPRQANRKAGCAVTSLLASELTKDDAM 1243
+ +RK + A E+T++ A+
Sbjct: 1039 LCKLKRSRKR----SGSQALEVTRERAI 1062
Score = 173 bits (439), Expect = 8e-43
Identities = 139/506 (27%), Positives = 238/506 (47%), Gaps = 61/506 (12%)
Query: 165 LESLRVSLNNNPVSWVQTF-GAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKA 223
+E L+ +L P+ +V F EGL LL+ L+ + + +SR +I C+KA
Sbjct: 130 VEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDH------ATCESRIHTSLIGCIKA 183
Query: 224 FMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAM 283
MNN G +L E I + +++ + ++L A+C++P +++VL+AM
Sbjct: 184 LMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGG---HKKVLQAM 240
Query: 284 TE-RAEMDEVERFQPLLDGLKSGT-----TIALKVGCLQLINALITPA---EELDFRVHI 334
+ E RFQ LL+ L + LK + INA++ + L+FR+H+
Sbjct: 241 LHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHL 300
Query: 335 RSELMRLGLHQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVF 394
R E + LG+ V+ LR+ EN + L+ F+ ED +L R D + ++ +++F
Sbjct: 301 RYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMF 360
Query: 395 QILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYY---KLIEECISQIVLH-KNGADP 450
+++ +K ++A P LS+L H L + Y+ Y+ +L++ + QIVL + G DP
Sbjct: 361 ELIHKKLKYTEAYPCLLSVLHHCL--QMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDP 418
Query: 451 DFKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFE 510
D ++ +++ +I++ +V++ +A + K+ EL +++ E + E
Sbjct: 419 DLAPLE-NFNVKNIVNMLINENEVKQWRDQAEKFRKE-------HMELVSRLERKERECE 470
Query: 511 QKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAI 570
K + + L+ K ++A E Q+L Q G+VA+L +L + LS +
Sbjct: 471 TKTLEKEEMMRTLNKMKDKLARESQELR----QARGQVAELVAQLSE-------LSTGPV 519
Query: 571 TVPPSVPSRAPVPPAPPLPGDSGTII-----PPPPAPGDSTTPPPPPPPPPPPPPLPGGV 625
+ PP PP PL S PPPP P PPPPPP PP PP P G
Sbjct: 520 SSPP--------PPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPG- 570
Query: 626 CISSPPSLPGGTAISPPPPLSGDATI 651
+PP L G + P S D +
Sbjct: 571 ---APPCLGMGLPLPQDPYPSSDVPL 593
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 232 bits (592), Expect = 1e-60
Identities = 207/808 (25%), Positives = 368/808 (45%), Gaps = 114/808 (14%)
Query: 457 LQIEIEGL-IDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQ-VEMKKMESDFEQKLQ 514
LQ E L +D +++ ++ +S+ +++ LD+ L+ E K + ++LQ
Sbjct: 346 LQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNIFDVGALLEDTETKNAVLEHMEELQ 405
Query: 515 DLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPP 574
E+ AL +E+ + A + + A++++L ++++ KELE ++ + +A + P
Sbjct: 406 ----EQVALLTERLRDA--ENESMAKIAELEKQLSQARKELETLRERFSESTAMGASRRP 459
Query: 575 SVPSRAPVPPAPPLPG---------DSGTIIPPPPAPGDSTT----PPPPPPPPPPPPPL 621
P +AP P AP P + +I PGD+ + P P P
Sbjct: 460 PEPEKAP-PAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518
Query: 622 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 681
PG S P L A P P A PPPPPLP G+PSP P
Sbjct: 519 PGVPTGSPSPDL--APAAEPAP----GAAPPPPPPLP---GLPSPQEAPPSA-------- 561
Query: 682 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP 741
PP PPLPGS PPP PPLPG+ +PPPPPP PPPPP GP +PPP
Sbjct: 562 ------PPQAPPLPGSPE-PPPAPPLPGD--LPPPPPP-------PPPPPGTDGP-VPPP 604
Query: 742 PPGMGMPPPPPFGFGVPAA-----PVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDC 796
PP PPPPP G G P A L G+ KK + + ++ NW L ++
Sbjct: 605 PP----PPPPPPG-GPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTV 659
Query: 797 FWTKVKEDRFENNELFAKLTLT-FSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSK 855
F T++ +++ + +L ++ F Q KT + K +K + ++++
Sbjct: 660 F-TELNDEK-----VLQELDMSDFEEQFKTKSQGPSLDLSALKSKAAQKAPSKATLIEAN 713
Query: 856 TAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDE-- 913
A+NL+I L + + I I + L ++ L++ +P + +++ + E
Sbjct: 714 RAKNLAITLRKGNLGAERICQAIEAYDLQALGLDFLELLMRFLPTEYERSLITRFEREQR 773
Query: 914 -YDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSES 972
++L+E ++F + +PRL R+ + F F + + + P++ ++ AA ++ S+
Sbjct: 774 PMEELSEEDRFMLCFSRIPRLPERMTTLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDK 833
Query: 973 FSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYP 1032
+LEI L GNYMN+ R A A+GF + L L + KSTD+K TLLH+L ++ YP
Sbjct: 834 LRQILEIVLAFGNYMNSSKRGA-AYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYP 892
Query: 1033 DVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTS 1092
+ F +L ++KA VS +++ ++ +++ + +R+ + D V K
Sbjct: 893 QLTGFHSDLHFLDKAGSVSLDSVLADVRSLQRGLELTQREF------VRQDDCMVLK--E 944
Query: 1093 FVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNFRNMFLQAVKEN 1152
F++ +KL + ++ + EYF +PK S FF ++F + +K
Sbjct: 945 FLRANSPTMDKLLADSKTAQEAFESVVEYFGENPKTTSPGLFF-------SLFSRFIKAY 997
Query: 1153 QKRRETEEKMRRAKLAKE---------------------KAEKERLEKQQKREQLIDMNA 1191
+K + E+ ++ A+E + + + + + ++R+Q +
Sbjct: 998 KKAEQEVEQWKKEAAAQEAGADTPGKGEPPAPKSPPKARRPQMDLISELKRRQQKEPLIY 1057
Query: 1192 EGDETGVMDSLLEALQSGAAFRRKRGPR 1219
E D G ++ ++ +++ F + G R
Sbjct: 1058 ESDRDGAIEDIITVIKT-VPFTARTGKR 1084
Score = 111 bits (277), Expect = 5e-24
Identities = 102/431 (23%), Positives = 184/431 (42%), Gaps = 71/431 (16%)
Query: 215 HEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPED 274
H I CL+A MN + G ++ + + +++ P +LL+A+C++ D
Sbjct: 228 HVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHD 287
Query: 275 MNERVLEAMTERAEM-DEVERFQPLLDGLKS-GTTIALKVGCLQLINALITPAEELDFRV 332
+ +L A E+ E RF+ L++ ++ + I V C+Q IN ++ E ++FRV
Sbjct: 288 I---ILAAFDNFKEVCGEQHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVENMNFRV 344
Query: 333 HIRSELMRLGLHQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDD------IRME 386
++ E LGL L+ LR E++ ++VQ+ + ++ +D+ L+D +
Sbjct: 345 FLQYEFTHLGLDLYLERLRLTESDKLQVQIQAY----LDNIFDVGALLEDTETKNAVLEH 400
Query: 387 MDDFNEVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKN 446
M++ E +L ++D++ E +++I
Sbjct: 401 MEELQEQVALLTERLRDAE-----------------------------NESMAKI----- 426
Query: 447 GADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKME 506
A+ + + + E+E L ++ + T + S + E EK + T L+++++++E
Sbjct: 427 -AELEKQLSQARKELETLRERFSESTAMGASR-RPPEPEKAPPAAPTRPSALELKVEELE 484
Query: 507 SDFEQKLQDLQGEKDALHSEKQQIA-----------------TEKQDLEAEVSQLTGEVA 549
+ ++ L+G DA+ E +A + DL G
Sbjct: 485 E--KGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAP 542
Query: 550 KLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP 609
L + +A PP +P PPAPPLPGD PPPP P + P
Sbjct: 543 PPPPPLPGLPSPQEAPPSAPPQAPP-LPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPV 601
Query: 610 PPPPPPPPPPP 620
PPPPPPPPPPP
Sbjct: 602 PPPPPPPPPPP 612
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 229 bits (585), Expect = 1e-59
Identities = 169/577 (29%), Positives = 276/577 (47%), Gaps = 77/577 (13%)
Query: 641 PPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGI 700
PPPP A+IPPPPPLP G+G SP+ PP PP+ +PPPPPP
Sbjct: 646 PPPP----ASIPPPPPLPSGLGSLSPA--------PPMPPVSAGPPLPPPPPP------- 686
Query: 701 PPPPPPLPGEAGMPPPPPPLPGGPGIP--PPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP 758
PPP P P AG PPPPPP P +P P PP PGGP PPPPG+ PPPP FG+
Sbjct: 687 -PPPLPPPSSAGPPPPPPP----PPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLG 741
Query: 759 AAPVLPFGLTPKK-LYKPEVQLRRPNWSKLVAEDLSQDC---FWTKVKEDRFENNELFAK 814
++ P+K +P ++ W+++ D SQ+ W ++E + F
Sbjct: 742 SSS----SQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEY 797
Query: 815 LTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEI 874
L FS T K K E E+K V+ K +K+LD K +Q + I + S + ++I
Sbjct: 798 L---FSKDTTQQKKKPLSETYEKKNKVK----KIIKLLDGKRSQTVGILISSLHLEMKDI 850
Query: 875 KNVILEVNEAVLTESMIQNLIKQMPEPEQLKML-----SELKDEYDDLAESEQFGVVMGT 929
+ I V+++V+ + L + + ++L + + ++E L + EQF +
Sbjct: 851 QQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHELAQ 910
Query: 930 VPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNA 989
+P R I+F+ FSE + ++ ++ +T A ++L +S ++L + L GNYMN
Sbjct: 911 IPNFAERAQCIIFRSVFSEGITSLHRKVEIITRASKDLLHVKSVKDILALILAFGNYMNG 970
Query: 990 GSRNAG-AFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEK-- 1046
G+R G A G+++ L KL+D KS D + L+ ++ + L++ D+ A EK
Sbjct: 971 GNRTRGQADGYSLEILPKLKDVKSRDNGINLVDYVVKY-------YLRYYDQEAGTEKSV 1023
Query: 1047 -----------ASRVSAENLQKNLDQMKKQISDVERD--VQNFPAATDEKDKFVEKMTSF 1093
AS+V E+L K+L ++K+Q+ E+ V + + F +K+ F
Sbjct: 1024 FPLPEPQDFFLASQVKFEDLIKDLRKLKRQLEASEKQMVVVCKESPKEYLQPFKDKLEEF 1083
Query: 1094 VKDAQEQYNKLRMMHSNMETLYKELGEYFLFDP----KKLSVEEFFMDLHNFRNMFLQAV 1149
+ A++++ N + ++ YF P K+++ FM + F + F
Sbjct: 1084 FQKAKKEHKMEESHLENAQKSFETTVRYFGMKPKSGEKEITPSYVFMVWYEFCSDF---- 1139
Query: 1150 KENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQL 1186
K KR R K+A+E K EK+ + +++
Sbjct: 1140 KTIWKRESKNISKERLKMAQESVSKLTSEKKVETKKI 1176
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/76 (42%), Positives = 33/76 (43%), Gaps = 11/76 (14%)
Query: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPP---PPPPPPPPLPGGVCISS 629
PPS P PP PPLP P PP PG PPPP PPPPP G SS
Sbjct: 692 PPSSAGPPPPPPPPPLPNS-----PAPPNPGGPPPAPPPPGLAPPPPPGLFFGLG---SS 743
Query: 630 PPSLPGGTAISPPPPL 645
P AI P P+
Sbjct: 744 SSQCPRKPAIEPSCPM 759
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 206 bits (525), Expect = 9e-53
Identities = 152/558 (27%), Positives = 263/558 (47%), Gaps = 38/558 (6%)
Query: 647 GDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIP----- 701
GD I P + G + S + G ++ P S +PPPPPPLP S+ P
Sbjct: 487 GDGDIAILPVVASGT-LSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQN 545
Query: 702 -PPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG--GPGIPPPPPGMGMPPPPPFGFGVP 758
P PP+P PPPPPP P P PPPPP PG +P PP +P PP
Sbjct: 546 GPVTPPMPPP---PPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSS 602
Query: 759 AAPVLPFGLTPKKLYKP-EVQLRRP--NWSKLVAEDLSQDCFWTKVKEDRFENNELFAKL 815
V GL K+ KP + + R P NW L ++ F + ++ + L
Sbjct: 603 PTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVF------NEIDDERILEDL 656
Query: 816 TL-TFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEI 874
+ F KT + K+ + +K ++ +L++ A+NL+I L EI
Sbjct: 657 NVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEI 716
Query: 875 KNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDE---YDDLAESEQFGVVMGTVP 931
I + L ++ L++ +P ++K+L + E ++L++ ++F + +
Sbjct: 717 CKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIE 776
Query: 932 RLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGS 991
RL ++ + F F+E ++ + P++ ++ AA ++ S+ +LEI L +GNYMN+
Sbjct: 777 RLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSK 836
Query: 992 RNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVS 1051
R A +GF + L L DTKSTD+K TLLH+++ + + Y V F +EL +VEKA+ VS
Sbjct: 837 RGA-VYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVS 895
Query: 1052 AENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNM 1111
EN+ ++ ++++ + +R+ T K+ F+ + + + KL+
Sbjct: 896 LENVLLDVKELQRGMDLTKREYTMHDHNTLLKE--------FILNNEGKLKKLQDDAKIA 947
Query: 1112 ETLYKELGEYFLFDPKKLSVEEFFMDLHNFRNMFLQAVKENQKRRETE----EKMRRAKL 1167
+ + ++ +YF +PK FF F + QA +EN+ R++ E EK+ +
Sbjct: 948 QDAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEA 1007
Query: 1168 AKEKAEKERLEKQQKREQ 1185
E+ + + + KR+Q
Sbjct: 1008 LMEQQDPKSPSHKSKRQQ 1025
Score = 94.4 bits (233), Expect = 6e-19
Identities = 116/488 (23%), Positives = 191/488 (39%), Gaps = 96/488 (19%)
Query: 215 HEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPED 274
H I CL+A MN ++G ++ + + +++ P +LL+A+C++
Sbjct: 222 HVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLV---RG 278
Query: 275 MNERVLEAMTERAEM-DEVERFQPLLDGLKS-GTTIALKVGCLQLINALITPAEELDFRV 332
+E +L A E+ E +RF+ L++ ++ I V +Q IN +
Sbjct: 279 GHEIILSAFDNFKEVCGEKQRFEKLMEHFRNEDNNIDFMVASMQFINIV----------- 327
Query: 333 HIRSELMRLGLHQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDDIR-MEMDDFN 391
+ +E+ + RV L Q E L LD ++ E D
Sbjct: 328 -----------------VHSVEDMNFRVHL-----QYEFTKLGLDEYLDKLKHTESDKLQ 365
Query: 392 EVFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPD 451
Q L+ V D A + D E + + +EE I
Sbjct: 366 VQIQAYLDNVFDVGA-------------LLEDAETKNAALERVEELEENI---------- 402
Query: 452 FKCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQ 511
HL +++ ++ + +K+ + E + + K+LD + ++ + ++
Sbjct: 403 ---SHLSEKLQDTENEAM--SKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKE 457
Query: 512 KLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAIT 571
K + +Q + EK+ EKQ + G++A L + M S A +
Sbjct: 458 KEEAIQRQSTL---EKKIHELEKQGTIKIQKKGDGDIAILPV-VASGTLSMGSEVVAGNS 513
Query: 572 VPPSV--PSRAPVPPAPP-LPGDS--------GTIIPPPPAPGDSTTPPPPPPPPPPPPP 620
V P++ S P+PP PP LP S G + PP P P PPPPPPPPPPPPP
Sbjct: 514 VGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP 573
Query: 621 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 680
LPG P + P PPL+ +P PPLP G P+ G A+ P
Sbjct: 574 LPG----------PAAETV-PAPPLA--PPLPSAPPLP-GTSSPTVVFNSGLAAVKIKKP 619
Query: 681 LPGSARIP 688
+ R+P
Sbjct: 620 IKTKFRMP 627
>gi|145309324 FH2 domain containing 1 [Homo sapiens]
Length = 1143
Score = 195 bits (495), Expect = 3e-49
Identities = 142/515 (27%), Positives = 229/515 (44%), Gaps = 45/515 (8%)
Query: 667 SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLP----GEAGMPPPPPPLPG 722
S G P + G P PPPP PPPPPP P P PPP
Sbjct: 11 SDKENGNIATAPGFMIGQTPPPAPPPP-------PPPPPPSPPCSCSREECPSSPPP--- 60
Query: 723 GPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782
PPPPP PG P IPPPPPG+ PP G L KK ++R
Sbjct: 61 ----PPPPPLPGEPPIPPPPPGL---PPTTHMNGYS-------HLGKKK------RMRSF 100
Query: 783 NWSKLVAEDL-SQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSV 841
W + E + + WT + F Q T+K+ + G S
Sbjct: 101 FWKTIPEEQVRGKTNIWTLAARQEHHYQIDTKTIEELFGQQEDTTKSSLPRRGRTLNSSF 160
Query: 842 QKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEP 901
++ + +E+ +LD+K + N+ IFL F+ + I I + ++ +K +PE
Sbjct: 161 REAR-EEITILDAKRSMNIGIFLKQFKKSPRSIVEDIHQGKSEHYGSETLREFLKFLPES 219
Query: 902 EQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVT 961
E++K L + L+ ++ F + VP R+ A++ K +F ++ +I +
Sbjct: 220 EEVKKLKAFSGDVSKLSLADSFLYGLIQVPNYSLRIEAMVLKKEFLPSCSSLYTDITVLR 279
Query: 962 AACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLH 1021
A +EL E ++L + L GN MNAG A GF +S L KL DTK+ M LLH
Sbjct: 280 TAIKELMSCEELHSILHLVLQAGNIMNAGGYAGNAVGFKLSSLLKLADTKANKPGMNLLH 339
Query: 1022 FLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATD 1081
F+A+ + +L F ++L HV+K +R+S EN + L + + ++ ++Q
Sbjct: 340 FVAQEAQKKDTILLNFSEKLHHVQKTARLSLENTEAELHLLFVRTKSLKENIQ------- 392
Query: 1082 EKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNF 1141
+ ++M F++ A E+ +L ++ L ++F D K + ++E F +F
Sbjct: 393 RDGELCQQMEDFLQFAIEKLRELECWKQELQDEAYTLIDFFCEDKKTMKLDECFQIFRDF 452
Query: 1142 RNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKER 1176
F +AVK+N R E +R+ + KE+ +K+R
Sbjct: 453 CTKFNKAVKDNHDREAQE--LRQLQRLKEQEQKQR 485
Score = 69.7 bits (169), Expect = 2e-11
Identities = 35/81 (43%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Query: 591 DSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDAT 650
++G I P T PP PPPPPPPPPP P C S P PPPPL G+
Sbjct: 14 ENGNIATAPGFMIGQTPPPAPPPPPPPPPPSP--PCSCSREECPSSPPPPPPPPLPGEPP 71
Query: 651 IPPPPPLPEGVGIPSPSSLPG 671
IPPPPP G+P + + G
Sbjct: 72 IPPPPP-----GLPPTTHMNG 87
Score = 58.9 bits (141), Expect = 3e-08
Identities = 35/85 (41%), Positives = 36/85 (42%), Gaps = 34/85 (40%)
Query: 611 PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 670
PPP PPPPPP P PPS PP S + PPP
Sbjct: 30 PPPAPPPPPPPP-------PPS--------PPCSCSREECPSSPPP-------------- 60
Query: 671 GGTAIPPPPPLPGSARIPPPPPPLP 695
PPPPPLPG IPPPPP LP
Sbjct: 61 -----PPPPPLPGEPPIPPPPPGLP 80
Score = 53.5 bits (127), Expect = 1e-06
Identities = 34/76 (44%), Positives = 38/76 (50%), Gaps = 20/76 (26%)
Query: 571 TVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPP--PPPPPPPPPPPLPGGVCIS 628
T P + + P PPAPP P PPPP+P S + P PPPPPPPPLPG
Sbjct: 20 TAPGFMIGQTP-PPAPPPPPP-----PPPPSPPCSCSREECPSSPPPPPPPPLPG----- 68
Query: 629 SPPSLPGGTAISPPPP 644
PP I PPPP
Sbjct: 69 EPP-------IPPPPP 77
Score = 45.8 bits (107), Expect = 3e-04
Identities = 25/66 (37%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 560 KEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP--PPP 617
KE +++ A + P AP PP PP P P PPPPP P PP
Sbjct: 13 KENGNIATAPGFMIGQTPPPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPLPGEPPI 72
Query: 618 PPPLPG 623
PPP PG
Sbjct: 73 PPPPPG 78
Score = 45.1 bits (105), Expect = 4e-04
Identities = 25/50 (50%), Positives = 27/50 (54%), Gaps = 13/50 (26%)
Query: 573 PPSVP---SRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP 619
PPS P SR P +PP P PPPP PG+ PP PPPPP PP
Sbjct: 42 PPSPPCSCSREECPSSPPPP-------PPPPLPGE---PPIPPPPPGLPP 81
Score = 34.3 bits (77), Expect = 0.78
Identities = 17/31 (54%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Query: 577 PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTT 607
PS P PP PPLPG+ IPPPP TT
Sbjct: 55 PSSPPPPPPPPLPGEPP--IPPPPPGLPPTT 83
>gi|119120861 formin-like 3 isoform 2 [Homo sapiens]
Length = 976
Score = 191 bits (486), Expect = 3e-48
Identities = 151/535 (28%), Positives = 246/535 (45%), Gaps = 63/535 (11%)
Query: 659 EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPP 718
E + P+ L G PP L A PPP LP +PPPP P +PPPPP
Sbjct: 433 EALARVGPAELSEGM---PPSDLDLLAPAPPPEEVLP----LPPPPAP-----PLPPPPP 480
Query: 719 PLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAP--VLPFGLTPKKLYKP- 775
PLP PP PP PG AAP VL GL+ ++ KP
Sbjct: 481 PLPDK--CPPAPPLPG------------------------AAPSVVLTVGLSAIRIKKPI 514
Query: 776 EVQLRRP--NWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTL-TFSAQTKTSKAKKDQ 832
+ + R P NW+ L +S F ++ ++ L L F KT
Sbjct: 515 KTKFRLPVFNWTALKPNQISGTVF------SELDDEKILEDLDLDKFEELFKTKAQGPAL 568
Query: 833 EGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQ 892
+ K +K ++ +L++ A+NL+I L +EI I + L ++
Sbjct: 569 DLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVE 628
Query: 893 NLIKQMPEPEQLKMLSELKDE---YDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQ 949
L++ +P ++K+L + + E ++LA ++F ++ V RL R+ + F F +
Sbjct: 629 CLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDN 688
Query: 950 VENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRD 1009
++ + P++ ++ AA ++ S+ +LEI L +GNYMN+ R A +GF + L L D
Sbjct: 689 LQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLD 747
Query: 1010 TKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDV 1069
TKSTD+KMTLLHF+A + YPD+ F EL VEKA+ VS EN+ ++ ++ + + +
Sbjct: 748 TKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELI 807
Query: 1070 ERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKL 1129
R+ + + +F+ + + +KL+ E Y + YF PK
Sbjct: 808 RRECSIHDNSV---------LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTT 858
Query: 1130 SVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKRE 1184
FF F + +A +EN+ R++ EE MR +LA+E + + Q+ +
Sbjct: 859 PPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNK 913
Score = 110 bits (274), Expect = 1e-23
Identities = 140/571 (24%), Positives = 225/571 (39%), Gaps = 157/571 (27%)
Query: 96 FEQMLLDMNLNEEKQQPLREKDIIIKREMVSQYLYTSKAGMSQKESSKSAMMYIQELRSG 155
F +L MNL +K + LR+ D K +++ + + YIQ+L+S
Sbjct: 38 FALVLSSMNLPPDKARLLRQYDNEKKWDLICD--------QERFQVKNPPHTYIQKLQSF 89
Query: 156 L-----------RDMPLLSCLESLRVSLNNNPVSWVQTF---GAEGLASLLDILK----- 196
L R L L +SL N + WV+ F +GL L+D L
Sbjct: 90 LDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCS 149
Query: 197 ---------------RLHDEKEETAGSYDSRNKHEIIRCLKAFMNNKFGIKTMLETEEGI 241
RL +K++ H I CL+A MN ++G ++ +
Sbjct: 150 VMYSTLPGRRALKNSRLVSQKDDV---------HVCILCLRAIMNYQYGFNLVMSHPHAV 200
Query: 242 LLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEM-DEVERFQPLLD 300
+ +++ P +LL+A+C++ +E +L A E+ E+ RF+ L++
Sbjct: 201 NEIALSLNNKNPRTKALVLELLAAVCLV---RGGHEIILAAFDNFKEVCKELHRFEKLME 257
Query: 301 GLKS-GTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQDLREIENEDMR 359
++ + I V C+Q IN ++ E+++FRVH++ E +LGL + LQ R E+E ++
Sbjct: 258 YFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQ 317
Query: 360 VQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTVKDSKAEPHFLSILQHLLL 419
VQ+ + ++ +D+ G L+D E + L V++ E H + + LL
Sbjct: 318 VQIQAY----LDNVFDVGGLLEDA--------ETKNVALEKVEE--LEEHVSHLTEKLLD 363
Query: 420 VRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKSEA 479
+ N+ R
Sbjct: 364 LENENMMR---------------------------------------------------- 371
Query: 480 KAAELEKKLDSELTARHELQVEMKKMESDFEQ--KLQDLQGEKDALHSEKQQIATEKQDL 537
AELEK+L L EL+ + E+ Q L+ L EK+ + + + L
Sbjct: 372 -VAELEKQL---LQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGL 427
Query: 538 EAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPS-VPSRAPVPPAPP-LPGDSGTI 595
E+ S+ V A LS +PPS + AP PP LP
Sbjct: 428 ESVDSEALARVGP------------AELSEG---MPPSDLDLLAPAPPPEEVLP------ 466
Query: 596 IPPPPAPGDSTTPPPPPPPP---PPPPPLPG 623
+PPPPAP PPPPPP P PP PPLPG
Sbjct: 467 LPPPPAP---PLPPPPPPLPDKCPPAPPLPG 494
>gi|119120874 formin-like 3 isoform 1 [Homo sapiens]
Length = 1027
Score = 191 bits (486), Expect = 3e-48
Identities = 151/535 (28%), Positives = 246/535 (45%), Gaps = 63/535 (11%)
Query: 659 EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPP 718
E + P+ L G PP L A PPP LP +PPPP P +PPPPP
Sbjct: 484 EALARVGPAELSEGM---PPSDLDLLAPAPPPEEVLP----LPPPPAP-----PLPPPPP 531
Query: 719 PLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAP--VLPFGLTPKKLYKP- 775
PLP PP PP PG AAP VL GL+ ++ KP
Sbjct: 532 PLPDK--CPPAPPLPG------------------------AAPSVVLTVGLSAIRIKKPI 565
Query: 776 EVQLRRP--NWSKLVAEDLSQDCFWTKVKEDRFENNELFAKLTL-TFSAQTKTSKAKKDQ 832
+ + R P NW+ L +S F ++ ++ L L F KT
Sbjct: 566 KTKFRLPVFNWTALKPNQISGTVF------SELDDEKILEDLDLDKFEELFKTKAQGPAL 619
Query: 833 EGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEVNEAVLTESMIQ 892
+ K +K ++ +L++ A+NL+I L +EI I + L ++
Sbjct: 620 DLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVE 679
Query: 893 NLIKQMPEPEQLKMLSELKDE---YDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQ 949
L++ +P ++K+L + + E ++LA ++F ++ V RL R+ + F F +
Sbjct: 680 CLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDN 739
Query: 950 VENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRD 1009
++ + P++ ++ AA ++ S+ +LEI L +GNYMN+ R A +GF + L L D
Sbjct: 740 LQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGA-VYGFKLQSLDLLLD 798
Query: 1010 TKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAENLQKNLDQMKKQISDV 1069
TKSTD+KMTLLHF+A + YPD+ F EL VEKA+ VS EN+ ++ ++ + + +
Sbjct: 799 TKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELI 858
Query: 1070 ERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKL 1129
R+ + + +F+ + + +KL+ E Y + YF PK
Sbjct: 859 RRECSIHDNSV---------LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTT 909
Query: 1130 SVEEFFMDLHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKRE 1184
FF F + +A +EN+ R++ EE MR +LA+E + + Q+ +
Sbjct: 910 PPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNK 964
Score = 99.4 bits (246), Expect = 2e-20
Identities = 107/418 (25%), Positives = 173/418 (41%), Gaps = 106/418 (25%)
Query: 215 HEIIRCLKAFMNNKFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPED 274
H I CL+A MN ++G ++ + + +++ P +LL+A+C++
Sbjct: 225 HVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLV---RG 281
Query: 275 MNERVLEAMTERAEM-DEVERFQPLLDGLKS-GTTIALKVGCLQLINALITPAEELDFRV 332
+E +L A E+ E+ RF+ L++ ++ + I V C+Q IN ++ E+++FRV
Sbjct: 282 GHEIILAAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRV 341
Query: 333 HIRSELMRLGLHQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNE 392
H++ E +LGL + LQ R E+E ++VQ+ + ++ +D+ G L+D E
Sbjct: 342 HLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAY----LDNVFDVGGLLEDA--------E 389
Query: 393 VFQILLNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDF 452
+ L V++ E H + + LL + N+ R
Sbjct: 390 TKNVALEKVEE--LEEHVSHLTEKLLDLENENMMR------------------------- 422
Query: 453 KCRHLQIEIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQ- 511
AELEK+L L EL+ + E+ Q
Sbjct: 423 ----------------------------VAELEKQL---LQREKELESIKETYENTSHQV 451
Query: 512 -KLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAI 570
L+ L EK+ + + + LE+ S+ V A LS
Sbjct: 452 HTLRRLIKEKEEAFQRRCHLEPNVRGLESVDSEALARVGP------------AELSEG-- 497
Query: 571 TVPPS-VPSRAPVPPAPP-LPGDSGTIIPPPPAPGDSTTPPPPPPPP---PPPPPLPG 623
+PPS + AP PP LP +PPPPAP PPPPPP P PP PPLPG
Sbjct: 498 -MPPSDLDLLAPAPPPEEVLP------LPPPPAP---PLPPPPPPLPDKCPPAPPLPG 545
>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
interacting protein [Homo sapiens]
Length = 1211
Score = 172 bits (435), Expect = 2e-42
Identities = 136/472 (28%), Positives = 220/472 (46%), Gaps = 47/472 (9%)
Query: 703 PPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPG---------------IPPPPPGMGM 747
PPPPL PPPPPPLP P G G +PPPPP +
Sbjct: 750 PPPPLS-----PPPPPPLPFHDAKPSSRSSDGSRGPAQALAKPLTQLSHPVPPPPPPP-L 803
Query: 748 PPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKED--- 804
PPP P A P+L GL ++ + ++R W ++ + S+ W ++ ED
Sbjct: 804 PPPVPC-----APPMLSRGLGHRRSETSHMSVKRLRWEQV---ENSEGTIWGQLGEDSDY 855
Query: 805 -RFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIF 863
+ + + L L F Q K K G E +KK+V E +L K A N SI
Sbjct: 856 DKLSDMVKYLDLELHFGTQ----KPAKPVPGPEP---FRKKEVVE--ILSHKKAYNTSIL 906
Query: 864 LGSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQF 923
L ++ E++ V++ + L + + L+ P+ ++ + ++ L+E +QF
Sbjct: 907 LAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQF 966
Query: 924 GVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLV 983
+ M +VP + RL ++ F+ E+ E I+ + + A EL+ S + +LE L +
Sbjct: 967 VLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAM 1026
Query: 984 GNYMNAGS-RNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELA 1042
GNY+N G + GF I+FL +L TK+ D K T LH LA+ +P++L F +L
Sbjct: 1027 GNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLP 1086
Query: 1043 HVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYN 1102
V A++V+ L +L + IS+++ Q+ +++ DKF M+SF++ AQ
Sbjct: 1087 TVPLAAKVNQRALTSDLADLHGTISEIQDACQSISPSSE--DKFAMVMSSFLETAQPALR 1144
Query: 1103 KL-RMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNFRNMFLQAVKENQ 1153
L + ME L K L +F D K + E FF F + F +A+ + Q
Sbjct: 1145 ALDGLQREAMEELGKALA-FFGEDSKATTSEAFFGIFAEFMSKFERALSDLQ 1195
Score = 45.8 bits (107), Expect = 3e-04
Identities = 27/63 (42%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 609 PPPPPPPPPPPPLPGGVCISSPPSLPGGTA-----ISPPPPLSGDATIPPPPPLPEGVGI 663
PPPP PPPPPPLP S S G P LS PPPPPLP V
Sbjct: 750 PPPPLSPPPPPPLPFHDAKPSSRSSDGSRGPAQALAKPLTQLSHPVPPPPPPPLPPPVPC 809
Query: 664 PSP 666
P
Sbjct: 810 APP 812
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 16/90 (17%)
Query: 558 AKKEMASLSAAAIT--VPPSVPSRAPVPPAP-----PLPGDSGTIIPPPPAPGDSTT--- 607
+ +E +SL+ ++I+ +PP S P PP P P S P A T
Sbjct: 733 SSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDAKPSSRSSDGSRGPAQALAKPLTQLS 792
Query: 608 -PPPPPPPPPPPPPLPGGVCISSPPSLPGG 636
P PPPPPPP PPP+P +PP L G
Sbjct: 793 HPVPPPPPPPLPPPVP-----CAPPMLSRG 817
Score = 33.9 bits (76), Expect = 1.0
Identities = 48/167 (28%), Positives = 58/167 (34%), Gaps = 49/167 (29%)
Query: 577 PSRAPVPPAPPLPGD----SGTIIPPPPAP-------------------GDSTTPPPPPP 613
PS P P P +PG+ GT +P P P G T
Sbjct: 520 PSECPEMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKMGTVSKSRA 579
Query: 614 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP--PPLPEGVGIPSPSSLPG 671
PP P P + P +L G +S P + +P P PL G G+ SPSS
Sbjct: 580 SPPGPSP----AVTTGPRTLSG---VSWP----SERLLPSPCYHPLCSG-GLASPSS--- 624
Query: 672 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPP 718
+ P L S P P PG I P PP P P PP
Sbjct: 625 -SESHPYASLDSSRA----PSPQPGPGPICPDSPPSPD----PTRPP 662
>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
Length = 1439
Score = 144 bits (363), Expect = 5e-34
Identities = 123/474 (25%), Positives = 219/474 (46%), Gaps = 52/474 (10%)
Query: 710 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP-PG-MGMPPPPPFGFGVPAAPVLPFGL 767
EA PPPPPP P G+PPPPP P IPPPP PG + +PPPP F
Sbjct: 842 EAPGPPPPPP-PTFLGLPPPPPPPLLDSIPPPPVPGNLLVPPPPVFN------------- 887
Query: 768 TPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKV-------KEDRFENNELFAKLTLTFS 820
P+ L +V +P ++K + + FW +V K +R L++KL
Sbjct: 888 APQGLGWSQVPRGQPTFTK---KKKTIRLFWNEVRPFDWPCKNNRRCREFLWSKLE---P 941
Query: 821 AQTKTSKAKKDQEGGEEKKSVQKK-----KVKELKVLDSKTAQNLSIFLGSFRMPYQEIK 875
+ TS+ + E ++ SV KK K +E+ VLDSK + ++I L + P + IK
Sbjct: 942 IKVDTSRLEHLFESKSKELSVSKKTAADGKRQEIIVLDSKRSNAINIGL-TVLPPPRTIK 1000
Query: 876 NVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSE--LKDEYDDLAESEQFGVVMGTVPRL 933
IL +E L + I+ ++ +P E+ + + E L + L +EQF + + ++ L
Sbjct: 1001 IAILNFDEYALNKEGIEKILTMIPTDEEKQKIQEAQLANPEIPLGSAEQFLLTLSSISEL 1060
Query: 934 RPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRN 993
RL+ FK+ + + + ++ + ++L +++ +L L +GN++N +
Sbjct: 1061 SARLHLWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTNAK 1120
Query: 994 AGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASRVSAE 1053
A F +S+L K+ + K T K +LLH + + ++PD E+ + ++++V +
Sbjct: 1121 A----FELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFD 1176
Query: 1054 NLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMET 1113
LQ NL QM+++ D A + K ++M+ F+KD E+ L+++H +
Sbjct: 1177 QLQDNLCQMERRCK-ASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRIIN 1235
Query: 1114 LYKELGEYFLFDPKKLS----------VEEFFMDLHNFRNMFLQAVKENQKRRE 1157
+ + P + + EF ++ R LQ ++ RE
Sbjct: 1236 RFHSFLLFMGHPPYAIREVNINKFCRIISEFALEYRTTRERVLQQKQKRANHRE 1289
Score = 52.8 bits (125), Expect = 2e-06
Identities = 29/69 (42%), Positives = 35/69 (50%), Gaps = 25/69 (36%)
Query: 601 APGDSTTPPPPPP-----PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPP 655
APG PPPPPP PPPPPPPL + PPPP+ G+ +PPPP
Sbjct: 843 APGP---PPPPPPTFLGLPPPPPPPLLDSI---------------PPPPVPGNLLVPPPP 884
Query: 656 PL--PEGVG 662
P+G+G
Sbjct: 885 VFNAPQGLG 893
Score = 45.1 bits (105), Expect = 4e-04
Identities = 27/66 (40%), Positives = 32/66 (48%), Gaps = 12/66 (18%)
Query: 580 APVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP--SLPGGT 637
AP PP PP P G +PPP PPPP PPPP+PG + + PP + P G
Sbjct: 843 APGPPPPPPPTFLG--LPPP--------PPPPLLDSIPPPPVPGNLLVPPPPVFNAPQGL 892
Query: 638 AISPPP 643
S P
Sbjct: 893 GWSQVP 898
Score = 43.1 bits (100), Expect = 0.002
Identities = 26/81 (32%), Positives = 30/81 (37%), Gaps = 40/81 (49%)
Query: 611 PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 670
P PPPPPPP G +PPPPP P I
Sbjct: 844 PGPPPPPPPTFLG---------------------------LPPPPPPPLLDSI------- 869
Query: 671 GGTAIPPPPPLPGSARIPPPP 691
PPPP+PG+ +PPPP
Sbjct: 870 ------PPPPVPGNLLVPPPP 884
Score = 41.6 bits (96), Expect = 0.005
Identities = 21/40 (52%), Positives = 24/40 (60%), Gaps = 4/40 (10%)
Query: 573 PPSVPSRAPVPPAPPLPG-DSGTIIPPPPAPGDSTTPPPP 611
PP P+ +PP PP P DS IPPPP PG+ PPPP
Sbjct: 848 PPPPPTFLGLPPPPPPPLLDS---IPPPPVPGNLLVPPPP 884
>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
Length = 1164
Score = 133 bits (335), Expect = 9e-31
Identities = 123/499 (24%), Positives = 217/499 (43%), Gaps = 61/499 (12%)
Query: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 746
IP P PPLP +G+PPPPP PPPPP+ G PFP PPPP
Sbjct: 569 IPAPSPPLPLLSGVPPPPP--------LPPPPPIKG--------PFP-----PPPP---- 603
Query: 747 MPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDC--FWTKVKED 804
+P P VP + LP KL+ E++L + V+ C W +
Sbjct: 604 LPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHG---VSASRFGPCATLWASLDPV 660
Query: 805 RFENNELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFL 864
+ A+L F ++ K + ++ GE ++++ VLD K + ++I L
Sbjct: 661 SVDT----ARLEHLFESRAK--EVLPSKKAGEGRRTM-------TTVLDPKRSNAINIGL 707
Query: 865 GSFRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDD--LAESEQ 922
+ P IK +L +E +++ I+ L+ MP E+ + + E + D L +E
Sbjct: 708 TTL-PPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAEN 766
Query: 923 FGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLL 982
F + + ++ L RL FKL + I + + E+L ++ +F +L L
Sbjct: 767 FLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLA 826
Query: 983 VGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELA 1042
VGN++N GS+++ GF +S+L K+ + K T ++ +LLH L L P+ E+
Sbjct: 827 VGNFLN-GSQSS---GFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIP 882
Query: 1043 HVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYN 1102
+ + ++V E L +NL Q++++ E +++ A + ++T F+ +
Sbjct: 883 ALTRCAKVDFEQLTENLGQLERRSRAAEESLRSL-AKHELAPALRARLTHFLDQCARRVA 941
Query: 1103 KLRMMHSNMETLYKELGEYFLFDPKKL----------SVEEFFMDLHNFRNMFLQAVKEN 1152
LR++H + + Y + P+ ++ EF ++ R LQ ++
Sbjct: 942 MLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQ 1001
Query: 1153 QKRRETEEKMRRAKLAKEK 1171
RE + R EK
Sbjct: 1002 ATYRERNKTRGRMITETEK 1020
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/64 (46%), Positives = 35/64 (54%), Gaps = 12/64 (18%)
Query: 613 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGG 672
P P PP PL GV PP LP PPPP+ G PPPPPLP + P P S+P
Sbjct: 570 PAPSPPLPLLSGV--PPPPPLP------PPPPIKGP--FPPPPPLP--LAAPLPHSVPDS 617
Query: 673 TAIP 676
+A+P
Sbjct: 618 SALP 621
Score = 48.1 bits (113), Expect = 5e-05
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 18/86 (20%)
Query: 556 EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP-- 613
ED ++M L+ ++ +P+ P+PPLP SG +PPPP PPPPP
Sbjct: 551 EDEDQDM--LNVESVEAGKDIPA-----PSPPLPLLSG--VPPPPP-----LPPPPPIKG 596
Query: 614 PPPPPPPLPGGVCISSPPSLPGGTAI 639
P PPPPPLP + P S+P +A+
Sbjct: 597 PFPPPPPLP--LAAPLPHSVPDSSAL 620
Score = 40.4 bits (93), Expect = 0.011
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 15/64 (23%)
Query: 640 SPPPPLSGDATIPPPPPL--PEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGS 697
+P PPL + +PPPPPL P + P PPPPPLP +A P P +P S
Sbjct: 571 APSPPLPLLSGVPPPPPLPPPPPIKGP----------FPPPPPLPLAA---PLPHSVPDS 617
Query: 698 AGIP 701
+ +P
Sbjct: 618 SALP 621
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 118 bits (296), Expect = 3e-26
Identities = 79/204 (38%), Positives = 93/204 (45%), Gaps = 41/204 (20%)
Query: 569 AITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPA----PGDS--------------TTPPP 610
A + PP S + P+P D+ +PPPPA P D+ +P
Sbjct: 243 ASSYPPPPQSDSASSPSPSFSEDN---LPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH 299
Query: 611 PPPPPP---PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 667
PPP PP PP P PG + PP+ P PPPP+ G IPPPPP P G G P
Sbjct: 300 PPPAPPLGSPPGPKPG---FAPPPAPP-----PPPPPMIG---IPPPPP-PVGFGSPGTP 347
Query: 668 SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP 727
P + PP P +A PPPPPP +PPPP P PPPPPP P G P
Sbjct: 348 PPPSPPSFPPHPDF--AAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG---P 402
Query: 728 PPPPFPGGPGIPPPPPGMGMPPPP 751
PPPPF G G P PP + P
Sbjct: 403 PPPPFTGADGQPAIPPPLSDTTKP 426
Score = 116 bits (290), Expect = 2e-25
Identities = 79/184 (42%), Positives = 86/184 (46%), Gaps = 30/184 (16%)
Query: 598 PPPAPGDSTTPPPPPPP----PPPPPPLPGGVCISSPPSLPG---GTAISPPPPLSGDAT 650
PPP DS + P P PPPP V L G + +SP P
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP------ 300
Query: 651 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-GSAGIPPPP----- 704
PP PPL G P P P PPPPP+ G IPPPPPP+ GS G PPPP
Sbjct: 301 -PPAPPLGSPPG-PKPGFAPPPAPPPPPPPMIG---IPPPPPPVGFGSPGTPPPPSPPSF 355
Query: 705 PPLPGEAGMPPPPPPLPGG-PGIPPPP---PFPGGPGIPPPPPGMGMPPPPPFGFGVPAA 760
PP P A PPPPPP P +PPPP P G P PPPPP G PPPPPF G
Sbjct: 356 PPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG-PPPPPF-TGADGQ 413
Query: 761 PVLP 764
P +P
Sbjct: 414 PAIP 417
Score = 52.4 bits (124), Expect = 3e-06
Identities = 37/88 (42%), Positives = 38/88 (43%), Gaps = 24/88 (27%)
Query: 573 PPSVPSRAPVP--PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 630
PP P A P P PPL +G PP PPPPPPP PPPPP G
Sbjct: 366 PPPPPPAADYPTLPPPPLSQPTGGAPPP---------PPPPPPPGPPPPPFTGA------ 410
Query: 631 PSLPGGTAISPPPPLSGDATIPPPPPLP 658
G AI PPPLS T P LP
Sbjct: 411 ---DGQPAI--PPPLSD--TTKPKSSLP 431
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 118 bits (295), Expect = 4e-26
Identities = 69/155 (44%), Positives = 75/155 (48%), Gaps = 46/155 (29%)
Query: 597 PPPPAPGDSTTPPPPPPP----PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIP 652
PPPP P PPPPPPP PPPPP G PPPP P
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPP--------------ARGRGAPPPPPSRAPTAAP 322
Query: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSA--GIPPPPPPLPGE 710
PPPP PS S+ A+PPPPP + PPPPP LP SA G PPPPP + G
Sbjct: 323 PPPP-------PSRPSV----AVPPPPP---NRMYPPPPPALPSSAPSGPPPPPPSVLGV 368
Query: 711 AGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGM 745
+ PPPP PPPPP PG PPPPPG+
Sbjct: 369 GPVAPPPP--------PPPPPPPG----PPPPPGL 391
Score = 109 bits (273), Expect = 1e-23
Identities = 60/129 (46%), Positives = 63/129 (48%), Gaps = 16/129 (12%)
Query: 640 SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 699
+PPPP PPPPP P G P P + G PPPPP PPPPPP S
Sbjct: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPAR--GRGAPPPPPSRAPTAAPPPPPPSRPSVA 333
Query: 700 IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG----GPGIPPPPPGMGMPPPPPFGF 755
+PPPPP PPPPP LP PPPP P GP PPPPP PPPPP
Sbjct: 334 VPPPPP----NRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP---PPPPP--- 383
Query: 756 GVPAAPVLP 764
G P P LP
Sbjct: 384 GPPPPPGLP 392
Score = 105 bits (261), Expect = 4e-22
Identities = 73/195 (37%), Positives = 87/195 (44%), Gaps = 49/195 (25%)
Query: 532 TEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGD 591
+E Q + E S++ + + T +E K E+ R PP PP P
Sbjct: 242 SEAQLKDRETSKVIYDFIEKTGGVEAVKNEL----------------RRQAPPPPP-PSR 284
Query: 592 SGTIIPPPPAPGDSTTPPPPP-----PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLS 646
G PPPP P ++ PPPPP PPPPP P PPS P A+ PPPP
Sbjct: 285 GGP--PPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRP-SVAVPPPPP-- 339
Query: 647 GDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPP 706
+ PPPPP PSS P G PPPP + G + PPPPP PPPPPP
Sbjct: 340 -NRMYPPPPP-------ALPSSAPSGPP-PPPPSVLGVGPVAPPPPP-------PPPPPP 383
Query: 707 LPGEAGMPPPPPPLP 721
PPPPP LP
Sbjct: 384 ------GPPPPPGLP 392
Score = 56.6 bits (135), Expect = 1e-07
Identities = 31/68 (45%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 697 SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFG 756
+ G+ L +A PPPPP GGP PPPPP GP PPP G G PPPPP
Sbjct: 262 TGGVEAVKNELRRQAP--PPPPPSRGGPPPPPPPPHNSGPP-PPPARGRGAPPPPPSRAP 318
Query: 757 VPAAPVLP 764
A P P
Sbjct: 319 TAAPPPPP 326
Score = 37.4 bits (85), Expect = 0.092
Identities = 20/43 (46%), Positives = 20/43 (46%), Gaps = 9/43 (20%)
Query: 727 PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTP 769
PPPPP GGP PP PPPPP G P P G P
Sbjct: 278 PPPPPSRGGP-----PP----PPPPPHNSGPPPPPARGRGAPP 311
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 117 bits (293), Expect = 7e-26
Identities = 90/249 (36%), Positives = 94/249 (37%), Gaps = 74/249 (29%)
Query: 577 PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLP-- 634
P R P PP P G PP G+ + PPP P P PP GG PP P
Sbjct: 47 PQRTPPPPGKP----EGR----PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGK 98
Query: 635 -------GGTAISPPPPLSGDATIPP---------PPPLPEGVGIPSPSSLPGGTAIPPP 678
GG PPP G PP PPP P G P GG P
Sbjct: 99 PEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP---GKPEGPPPQGGNQSQGP 155
Query: 679 PPLPGSARIPPP--------PPPLPGSAGIPPP--------PPPLPGEAGMPPP------ 716
PP PG PPP PPP PG PPP PPP PG+ PPP
Sbjct: 156 PPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 215
Query: 717 --PPPLPGGPGIPP---------PPPFPGGPGIP----------PPPPGMGMPPPPPFGF 755
PPP PG P PP PPP PG P P PPPPG PPPP
Sbjct: 216 QGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPP--G 273
Query: 756 GVPAAPVLP 764
G P P+ P
Sbjct: 274 GNPQQPLPP 282
Score = 116 bits (290), Expect = 2e-25
Identities = 87/230 (37%), Positives = 93/230 (40%), Gaps = 50/230 (21%)
Query: 577 PSRAPVPPAPPLPGDSGTIIPPP---------PAPGDSTTPPPPPPPPPPPPPLPGGVCI 627
P R P PP G + + PPP P G+ + PPP P P PP GG
Sbjct: 72 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 131
Query: 628 SSPPSLPGGTAISPPPPLSGDATIPPPPP-LPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 686
PP PG PPP + PPP P PEG P P GG PPP PG
Sbjct: 132 QGPPPRPGKPE-GPPPQGGNQSQGPPPRPGKPEG---PPPQ---GGNQSQGPPPHPGKPE 184
Query: 687 IPPP--------PPPLPGSAGIPPP--------PPPLPGEAGMPPP--------PPPLPG 722
PPP PPP PG PPP PPP PG+ PP PPP PG
Sbjct: 185 GPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPG 244
Query: 723 GPGIPPP--------PPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764
P PPP PP PG P PPPP G P PP G P P P
Sbjct: 245 KPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPP-PAGKPQGPPPP 293
Score = 111 bits (278), Expect = 4e-24
Identities = 80/204 (39%), Positives = 84/204 (41%), Gaps = 33/204 (16%)
Query: 573 PPSVPSRAPVPPA---------PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPG 623
PP P + PP PP PG PPP G+ + PPP P P PP G
Sbjct: 113 PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG---PPPQGGNQSQGPPPRPGKPEGPPPQG 169
Query: 624 GVCISSPPSLPGGTAISPPPPLSGDATIPPP-PPLPEGVGIPSPSSLPGGTAIPPPPPLP 682
G PP PG PPP + PPP P PEG P P GG PPP P
Sbjct: 170 GNQSQGPPPHPGKPE-GPPPQGGNQSQGPPPRPGKPEG---PPPQ---GGNQSQGPPPRP 222
Query: 683 GSARIPPP--------PPPLPGSAGIPPP----PPPLPGEAGMPPPPPPLPGGPGIPPPP 730
G PP PPP PG PPP P P G P PPP G P P PP
Sbjct: 223 GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPP 282
Query: 731 PFPGGPGIPPPPPGMGMPPPPPFG 754
P G P PPPPP G P PP G
Sbjct: 283 P-AGKPQGPPPPPQGGRPHRPPQG 305
Score = 105 bits (262), Expect = 3e-22
Identities = 80/224 (35%), Positives = 86/224 (38%), Gaps = 53/224 (23%)
Query: 600 PAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE 659
P G+ PPPP P P GG PP PG PPP + PPP P
Sbjct: 41 PQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPE-GPPPQGGNQSQGPPPRP--- 96
Query: 660 GVGIPSPSSLPGGTAIPPPPPLPGSARIPPP--------PPPLPGSAGIPPP-------- 703
G P GG PPP PG PPP PPP PG PPP
Sbjct: 97 --GKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQG 154
Query: 704 PPPLPGEAGMPPP--------PPPLPGGPGIPP---------PPPFPGGPGIPP------ 740
PPP PG+ PPP PPP PG P PP PPP PG P PP
Sbjct: 155 PPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 214
Query: 741 ---PPPGMGMPPPPPF-----GFGVPAAPVLPFGLTPKKLYKPE 776
PPP G P PP G P P P G P++ KP+
Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQ 258
Score = 31.6 bits (70), Expect = 5.1
Identities = 19/47 (40%), Positives = 20/47 (42%), Gaps = 4/47 (8%)
Query: 573 PPSVPSRAPVP---PAPPLPGDSGTII-PPPPAPGDSTTPPPPPPPP 615
PP P P P P PLP +G PPPP G PP PP
Sbjct: 262 PPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 116 bits (290), Expect = 2e-25
Identities = 84/199 (42%), Positives = 96/199 (48%), Gaps = 20/199 (10%)
Query: 569 AITVPPSVPSRA-PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCI 627
A VPP+ S A PVPP GDS T P P GDS PP PP PP+P
Sbjct: 560 ATPVPPTGDSEATPVPPT----GDSETA--PVPPTGDSGAPPVPPTGDSGAPPVPPTGDS 613
Query: 628 SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 687
+PP P G + +PP P +GD+ PP PP + P P P G + PP P G +
Sbjct: 614 GAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP---PTGDSGAPPVPPTGDSGA 670
Query: 688 PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP--GM 745
PP PP G AG PP PP G++G PP PP G G PP P G P PP
Sbjct: 671 PPVPPT--GDAGPPPVPPT--GDSGAPPVPPT--GDSGAPPVTP-TGDSETAPVPPTGDS 723
Query: 746 GMPPPPPFGFGVPAAPVLP 764
G PP PP G AAPV P
Sbjct: 724 GAPPVPPTG-DSEAAPVPP 741
Score = 100 bits (249), Expect = 9e-21
Identities = 68/171 (39%), Positives = 79/171 (46%), Gaps = 24/171 (14%)
Query: 598 PPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL 657
P P GDS P PP P+P P G + +PP P +GD+ PP PP
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVP-----------PTGDSGAPPVPPTGDSGAPPVPPT 610
Query: 658 PEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP 717
+ P P P G + PP P G + PP PP G +G PP PP G++G PP P
Sbjct: 611 GDSGAPPVP---PTGDSGAPPVPPTGDSGAPPVPP--TGDSGAPPVPP--TGDSGAPPVP 663
Query: 718 PPLPGGPGIPPPPPFPGGPGIPPPPP--GMGMPPPPPFGFGVPAAPVLPFG 766
P G G PP PP G G PP PP G PP PP G A PV P G
Sbjct: 664 P--TGDSGAPPVPP-TGDAGPPPVPPTGDSGAPPVPPTG-DSGAPPVTPTG 710
Score = 90.9 bits (224), Expect = 7e-18
Identities = 65/165 (39%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 567 AAAITVPPSVPSRAP-VPP-----APPLP--GDSGTIIPPPPAPGDSTTPPPPPPPPPPP 618
+ A VPP+ S AP VPP APP+P GDSG PP P GDS PP PP
Sbjct: 591 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGA--PPVPPTGDSGAPPVPPTGDSGA 648
Query: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP 678
PP+P +PP P G + +PP P +GDA PP PP + P P + G + PP
Sbjct: 649 PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPT--GDSGAPPV 706
Query: 679 PPLPGSARIPPPP---------PPLPGSAGIPPPPPPLPGEAGMP 714
P S P PP PP S P PP EA MP
Sbjct: 707 TPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMP 751
Score = 70.5 bits (171), Expect = 1e-11
Identities = 50/129 (38%), Positives = 57/129 (44%), Gaps = 18/129 (13%)
Query: 644 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPP 703
P D P PP + P P P G + P P G + PP PP G +G PP
Sbjct: 553 PTVTDQEATPVPPTGDSEATPVP---PTGDSETAPVPPTGDSGAPPVPPT--GDSGAPPV 607
Query: 704 PPPLPGEAGMPPPPPP-LPGGPGIPP-----PPPFP--GGPGIPPPPP--GMGMPPPPPF 753
PP G++G PP PP G P +PP PP P G G PP PP G PP PP
Sbjct: 608 PPT--GDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT 665
Query: 754 G-FGVPAAP 761
G G P P
Sbjct: 666 GDSGAPPVP 674
Score = 60.5 bits (145), Expect = 1e-08
Identities = 41/109 (37%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 567 AAAITVPPSVPSRAP-VPP-----APPLP--GDSGTIIPPPPAPGDSTTPPPPPPPPPPP 618
+ A VPP+ S AP VPP APP+P GD+G PP P GDS PP PP
Sbjct: 646 SGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGP--PPVPPTGDSGAPPVPPTGDSGA 703
Query: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 667
PP+ + P P G + +PP P +GD+ P PP + P+
Sbjct: 704 PPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPA 752
Score = 32.3 bits (72), Expect = 3.0
Identities = 21/57 (36%), Positives = 21/57 (36%), Gaps = 2/57 (3%)
Query: 707 LPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPG-MGMPPPPPFG-FGVPAAP 761
LP P P G P PP P PP G G PP PP G G P P
Sbjct: 552 LPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVP 608
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 112 bits (281), Expect = 2e-24
Identities = 87/206 (42%), Positives = 92/206 (44%), Gaps = 47/206 (22%)
Query: 582 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 641
VP PG +G PPPP P T P PP PP PP P PG PP P G + P
Sbjct: 211 VPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGP-PG------PP--PPGQVLPP 261
Query: 642 P---PPLSGDATIPPPPPLPEG--VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPG 696
P PP GD PPPP L G G P LP G PPPP+PG P PPPP G
Sbjct: 262 PLAGPPNRGDR--PPPPVLFPGQPFGQPPLGPLPPG----PPPPVPGYGPPPGPPPPQQG 315
Query: 697 SAGIPPPPPPLP----GEAGMP---PPPPPLPGGP-GIPPPPPF--------PGGPGIP- 739
PPPP P P G G P PPP LPG P G PPP P P G+P
Sbjct: 316 P---PPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPT 372
Query: 740 ------PPPPGMGMPPPPPFG-FGVP 758
PP G PPP G +G P
Sbjct: 373 SDSRGPPPTDPYGRPPPYDRGDYGPP 398
Score = 107 bits (268), Expect = 6e-23
Identities = 97/292 (33%), Positives = 117/292 (40%), Gaps = 45/292 (15%)
Query: 498 LQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELED 557
L+++ + ++ + K L G S+K K++L + +T + + E
Sbjct: 110 LEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEM 169
Query: 558 AKK---EMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP 614
+ + +S PP SRA P G G P PG P P P
Sbjct: 170 QSRKTTQSGQMSGEGKAGPPGGSSRAAFPQ-----GGRGRGRFPGAVPGGDRFPGPAGPG 224
Query: 615 PPPPPPLPGGVCISSPPSLPGGTAISP---------PPPLSGD---ATIPPPPPLPEG-- 660
PPP P P G PP P G P PPPL+G PPPP L G
Sbjct: 225 GPPP-PFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQP 283
Query: 661 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPL----PGEAGMP-- 714
G P LP G PPPP+PG PPP P P G PPPP P PG G P
Sbjct: 284 FGQPPLGPLPPG----PPPPVPGYG---PPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT 336
Query: 715 -PPPPPLPG-GPGIPPPPPFPGGPGIPPPPPGMGMP------PPPPFGFGVP 758
PPP LPG PG PPP P P PPP GMP PPP +G P
Sbjct: 337 LAPPPHLPGPPPGAPPPAPHV-NPAFFPPPTNSGMPTSDSRGPPPTDPYGRP 387
Score = 96.7 bits (239), Expect = 1e-19
Identities = 61/139 (43%), Positives = 65/139 (46%), Gaps = 16/139 (11%)
Query: 630 PPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPP 689
P ++PGG P G PPPP P G P P P G PP PP PG +PP
Sbjct: 208 PGAVPGGDRFPGPAGPGG-----PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQV-LPP 261
Query: 690 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG-GPGIPPPPPGMGMP 748
P P PPPP PG+ PP PLP G PPPP PG GP PPPP G P
Sbjct: 262 PLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG----PPPPVPGYGPPPGPPPPQQGPP 317
Query: 749 PPP-PFGFGVPAAPVLPFG 766
PPP PF P P P G
Sbjct: 318 PPPGPF----PPRPPGPLG 332
Score = 88.6 bits (218), Expect = 3e-17
Identities = 66/166 (39%), Positives = 70/166 (42%), Gaps = 26/166 (15%)
Query: 636 GTAISPPPPLSGDATIPP--------PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 687
G + PP S A P P +P G P P+ PGG PPPP P
Sbjct: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGG----PPPPFPAGQTP 236
Query: 688 PPPP---PPLPGSAGIPPP----PPPL---PGEAGMPPPPPPLPGGP-GIPPPPPFPGGP 736
P PP P PG G PPP PPPL P PPPP PG P G PP P P GP
Sbjct: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296
Query: 737 GIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782
PPP PG G PP PP P P PF P P + L P
Sbjct: 297 --PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340
Score = 45.8 bits (107), Expect = 3e-04
Identities = 31/83 (37%), Positives = 35/83 (42%), Gaps = 10/83 (12%)
Query: 573 PPSVPSRAPVPPAPPLP-GDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 631
PP P P PP PP P G T+ PPP PG PPP PPP P P
Sbjct: 316 PPPPPG--PFPPRPPGPLGPPLTLAPPPHLPG-------PPPGAPPPAPHVNPAFFPPPT 366
Query: 632 SLPGGTAISPPPPLSGDATIPPP 654
+ T+ S PP + PPP
Sbjct: 367 NSGMPTSDSRGPPPTDPYGRPPP 389
Score = 33.9 bits (76), Expect = 1.0
Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 6/72 (8%)
Query: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP-PPPPPP--PPPPLPGGVCISS 629
PP +P P P PP P + PPP G T+ PPP P PPP G
Sbjct: 340 PPHLPGPPPGAP-PPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRG--DYG 396
Query: 630 PPSLPGGTAISP 641
PP TA +P
Sbjct: 397 PPGREMDTARTP 408
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 111 bits (278), Expect = 4e-24
Identities = 91/251 (36%), Positives = 100/251 (39%), Gaps = 62/251 (24%)
Query: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPS 632
PP ++ PP+PP G PPP G+ PPPPP P PP GG PP
Sbjct: 40 PPQGGNKPQGPPSPP-----GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP- 93
Query: 633 LPGGTAISPPPPLSGDATIPP--PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 690
P G PPP GD + P PP P+G P P GG PPP PG + PPP
Sbjct: 94 -PPGKPQGPPP--QGDKSRSPRSPPGKPQG---PPPQ---GGNQPQGPPPPPGKPQGPPP 144
Query: 691 P-------PPLPGSAGIPPP-----------PP-----PLPGEAGMPPPPPPLPGGPGIP 727
PP PG PPP PP P P P PPP PG P P
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 204
Query: 728 PP--------PPFPGGPGIPPP-----------PPGMGMPPPPPFG---FGVPAAPVLPF 765
PP PP PG P PPP PPG PPP G G P P P
Sbjct: 205 PPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 264
Query: 766 GLTPKKLYKPE 776
G P+ KP+
Sbjct: 265 GPPPQGGNKPQ 275
Score = 105 bits (263), Expect = 2e-22
Identities = 90/269 (33%), Positives = 95/269 (35%), Gaps = 70/269 (26%)
Query: 573 PPSVPSRAPV-----PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCI 627
PP P P P PP PG PP GD + P PP P PP GG
Sbjct: 74 PPGKPQGPPPQGGNKPQGPPPPGKP----QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 129
Query: 628 SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG---------------VGIPSPSSLPGG 672
PP PG PPP PPPP P+G G P GG
Sbjct: 130 QGPPPPPGKPQ-GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188
Query: 673 TAIPPPPPLPGSARIPPPP-------PPLPGSAGIPPP-----------PP-----PLPG 709
PPP PG + PPP PP PG PPP PP P P
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ 248
Query: 710 EAGMPPPPPPLPGGPGIPPP--------PPFPGGPGIPPP-----------PPGMGMPPP 750
P PPP PG P PPP PP PG P PPP PPG PP
Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP 308
Query: 751 PPFG---FGVPAAPVLPFGLTPKKLYKPE 776
P G G P P P G P+ KP+
Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 337
Score = 101 bits (252), Expect = 4e-21
Identities = 79/223 (35%), Positives = 82/223 (36%), Gaps = 44/223 (19%)
Query: 577 PSRAPVPPAPPL--PGDSGTIIPPPPAPGDSTTPPP-----------PPPPPPPPPPLPG 623
P P PP P P G PP PG PPP PP P PPP G
Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188
Query: 624 GVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP-----P 678
PP P G PPP PPPP P+G P + PP P
Sbjct: 189 NQPQGPPP--PPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDNKSQSARSPPGKPQGP 245
Query: 679 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGG--------------- 723
PP G+ PPPPP G P PPP G PPPP P G
Sbjct: 246 PPQGGNQPQGPPPPP-----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Query: 724 PGIPPPPPFPGG--PGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764
PG P PP GG P PPPPPG PPP G P P P
Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ-GGNKPQGPPPP 342
Score = 95.9 bits (237), Expect = 2e-19
Identities = 78/227 (34%), Positives = 83/227 (36%), Gaps = 45/227 (19%)
Query: 577 PSRAPVPPAPPL--PGDSGTIIPPPPAPGDSTTPPP-----------PPPPPPPPPPLPG 623
P P PP P P G PP PG PPP PP P PPP G
Sbjct: 191 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGG 250
Query: 624 GVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP-----P 678
PP P G PPP PPPP P+G P S + PP P
Sbjct: 251 NQPQGPPP--PPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGGSKSRSSRSPPGKPQGP 307
Query: 679 PPLPGSARIPPPPPP-----LPGSAGIPPPPPPLPGEAGMPPP-----------PPPLPG 722
PP G+ PPPPP P G P PP PG+ PPP PP P
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367
Query: 723 GPGIP-------PPPPFPGGPGIP-PPPPGMGMPPPPPFGFGVPAAP 761
GP PPPP G P P PP G PP P G P+ P
Sbjct: 368 GPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414
Score = 95.1 bits (235), Expect = 4e-19
Identities = 79/237 (33%), Positives = 87/237 (36%), Gaps = 60/237 (25%)
Query: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCIS--SP 630
PP ++ PP PP G PPP G+ PPPP P PPP S SP
Sbjct: 184 PPQGGNQPQGPPPPP-----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238
Query: 631 PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 690
P P G PPP G+ PPPP + G P P G P PP PG + PPP
Sbjct: 239 PGKPQG-----PPPQGGNQPQGPPPPPGKPQGPP-----PQGGNKPQGPPPPGKPQGPPP 288
Query: 691 ------------------PPPLPGSAGIPPPPPP-----LPGEAGMPPPPPPLPGGPGIP 727
PPP G+ PPPPP P + G P PP PG P P
Sbjct: 289 QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 348
Query: 728 PP------------------PPFPGG--PGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764
PP PP G P PPPP G P G P P P
Sbjct: 349 PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405
Score = 82.0 bits (201), Expect = 3e-15
Identities = 65/189 (34%), Positives = 66/189 (34%), Gaps = 39/189 (20%)
Query: 577 PSRAPVPPAPPL--PGDSGTIIPPPPAPGDSTTPPP-----------PPPPPPPPPPLPG 623
P P PP P P G PP PG PPP PP P PPP G
Sbjct: 253 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG 312
Query: 624 GVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPG 683
PP P G PPP PPPP P+G PPP G
Sbjct: 313 NQPQGPPP--PPGKPQGPPPQGGNKPQGPPPPGKPQG-----------------PPPQGG 353
Query: 684 SARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 743
S PP G P PP G PPPP G P P PP G P PP PP
Sbjct: 354 SKSRSARSPP-----GKPQGPPQQEGN-NPQGPPPPAGGNPQQPQAPP-AGQPQGPPRPP 406
Query: 744 GMGMPPPPP 752
G P PP
Sbjct: 407 QGGRPSRPP 415
Score = 80.9 bits (198), Expect = 7e-15
Identities = 69/191 (36%), Positives = 74/191 (38%), Gaps = 51/191 (26%)
Query: 631 PSLPGGTAISPPPPLSGDATIPPPPP-LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPP 689
PSL G PP PP PP P+G P P GG PPP PG + PP
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQG---PPPQ---GGNQPQGPPPPPGKPQGPP 82
Query: 690 PP-------PPLPGSAGIPPP-------PPPLPGEAGMPPP--------PPPLPGGPGIP 727
P PP PG PPP P PG+ PPP PPP PG P P
Sbjct: 83 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142
Query: 728 PP--------PPFPGGPGIPPP-----------PPGMGMPPPPPFG---FGVPAAPVLPF 765
PP PP PG P PPP PPG PPP G G P P P
Sbjct: 143 PPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 202
Query: 766 GLTPKKLYKPE 776
G P+ KP+
Sbjct: 203 GPPPQGGNKPQ 213
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 109 bits (272), Expect = 2e-23
Identities = 99/309 (32%), Positives = 129/309 (41%), Gaps = 76/309 (24%)
Query: 527 KQQIATEKQDLEAEVSQL-TGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 585
+++I + +++E + ++ +G +A L+ K+ L A +T P S P VPP+
Sbjct: 1260 REKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRH-PPLYQAGLTPPLSPPKS--VPPS 1316
Query: 586 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPG----------GVCISSP----- 630
P G + P PPA TP P PPP L G G+ SP
Sbjct: 1317 VPARG----LQPQPPA-----TPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLD 1367
Query: 631 -------PSLPG-------------------GTAISP--PPPLSG--DATIPPPPPLPEG 660
+LP +AIS PPL+G D + P PPL
Sbjct: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPA 1427
Query: 661 VGIPSPSSLPG-----GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPP 715
+P P LPG P PP L + PP PPP P PPPPPP P + +P
Sbjct: 1428 AAVPGPPPLPGLPSANSNGTPEPPLL--EEKPPPTPPPAPTPQPQPPPPPP-PPQPALPS 1484
Query: 716 PPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP--AAPVLPFGLTPKKLY 773
PPP + P PPPPP P PPPPP M PPPPP P A P P +P+
Sbjct: 1485 PPPLVAPTPSSPPPPPLP-----PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPE--- 1536
Query: 774 KPEVQLRRP 782
PE+ RP
Sbjct: 1537 DPELPDTRP 1545
Score = 89.4 bits (220), Expect = 2e-17
Identities = 71/220 (32%), Positives = 97/220 (44%), Gaps = 56/220 (25%)
Query: 503 KKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEM 562
K+++ + ++ L+ L + S+++ + +DL+ +S L+D
Sbjct: 1364 KRLDEELKRNLETLP----SFSSDEEDSVAKNRDLQESISSAISA-------LDDPP--- 1409
Query: 563 ASLSAAAITVPPSVPSRAP---VPPAPPLPG-----DSGTIIPP------PPAPGDSTTP 608
L+ T P P AP VP PPLPG +GT PP PP P + TP
Sbjct: 1410 --LAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
Query: 609 PPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS 668
P PPPPPPPP P+LP SPPP ++ + PPPPPLP P P +
Sbjct: 1468 QPQPPPPPPPPQ----------PALP-----SPPPLVAPTPSSPPPPPLPP----PPPPA 1508
Query: 669 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLP 708
+P PPPP P +A PP P A P P LP
Sbjct: 1509 MPS-----PPPPPPPAAAPLAAPPEEP--AAPSPEDPELP 1541
Score = 77.0 bits (188), Expect = 1e-13
Identities = 62/209 (29%), Positives = 81/209 (38%), Gaps = 30/209 (14%)
Query: 607 TPPPPPPPPPPPPPLPGGVCI-SSPPSLPGGTAISPPPP-----LSGDATIPPPPPLPEG 660
+PPPPPP P P G+ + + P LP + PPPP + A P P G
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLP--LVLPPPPPQLLPSVLSHAPSPSPSASKVG 820
Query: 661 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-------GSAGIPP--PPPPLPGEA 711
V + P++ G PPPP PPPPPP+P S G+ P P P L E
Sbjct: 821 VHLLEPATRDGAPQPPPPP--------PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEE 872
Query: 712 GMPPPPPPLPGGPGIPPPPPFPGGPGIPPP-----PPGMGMPPPPPFGFGVPAAPVLPFG 766
+ PP + P PP PG G+ PP P P P G P L
Sbjct: 873 SLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSI 932
Query: 767 LTPKKLYKPEVQLRRPNWSKLVAEDLSQD 795
P L + E + P ++ + D
Sbjct: 933 CFPDSLLQDEERSFFPTMEEMFGGGAADD 961
Score = 65.5 bits (158), Expect = 3e-10
Identities = 65/244 (26%), Positives = 86/244 (35%), Gaps = 59/244 (24%)
Query: 574 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTP-------------PPPPPPPPPPPP 620
P +P P PP LP +++ P+P S + P PPPPPPPPP
Sbjct: 788 PDLPLVLPPPPPQLLP----SVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP 843
Query: 621 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSP-SSLPGGTAIPPPP 679
P + + + G +P P L + ++ PP + E +G P PG T + PP
Sbjct: 844 PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPN 903
Query: 680 PL---PGSARIPPPPPPLPGSAGIPPPPPPLP---------------------------G 709
P A P P +P P G
Sbjct: 904 SEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYG 963
Query: 710 EAGMPPPPPPLPGGPGIPPPPPF--PGGP-------GIPPPPPGMGMPP--PPPFGFGVP 758
+AG P G G PP PP P GP G P PG+G+ P PP V
Sbjct: 964 KAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVN 1023
Query: 759 AAPV 762
A P+
Sbjct: 1024 AEPL 1027
Score = 58.2 bits (139), Expect = 5e-08
Identities = 48/163 (29%), Positives = 57/163 (34%), Gaps = 48/163 (29%)
Query: 597 PPPPAPGDSTTPPPP----------------PPPPPP---------PPPLPG----GVCI 627
PPPP P +T P P PPPPP P P P GV +
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
Query: 628 SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGV-----------GIPSPSSLPGGTAIP 676
P + G PPPP PPPPP+P + PSP P ++
Sbjct: 824 LEPATRDGAPQPPPPPP-------PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPE-ESLD 875
Query: 677 PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP 719
PP + P PP PG G+ PP AG P P
Sbjct: 876 PPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSP 918
Score = 55.8 bits (133), Expect = 3e-07
Identities = 55/190 (28%), Positives = 67/190 (35%), Gaps = 39/190 (20%)
Query: 577 PSRAP-VPPAPPLPGDSGTIIPPPPAPGDSTTPP---PPPPPPPPPPPLPGGVCISSPPS 632
PS+AP VP + +G + P G + TPP PP PPPPP LP + + S
Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSS 252
Query: 633 LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPP 692
A P L + P PP PE +LP + P SA+ PPPPP
Sbjct: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPE-------RALPRQDTVIKHYQRPASAQPPPPPP 305
Query: 693 PL-------------------------PGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP 727
P P G P P P +AG P G G
Sbjct: 306 PAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAG---PSGATAGASGRA 362
Query: 728 PPPPFPGGPG 737
P GG G
Sbjct: 363 TGPEAAGGGG 372
Score = 52.0 bits (123), Expect = 4e-06
Identities = 67/231 (29%), Positives = 76/231 (32%), Gaps = 60/231 (25%)
Query: 593 GTIIPPPPAPGDSTTPPP-------------PPPPPPPPPPLPGGVCISSPPSL------ 633
G + P PPAPGD+ PP P P P I P SL
Sbjct: 885 GALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
Query: 634 ----------PGGTAI----SPPPPLSGD----ATIPPPPPLPEGVGIPSPSSLPGGTAI 675
GG A + PP GD A PP PP + G P G A
Sbjct: 945 SFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCP-----GRAS 999
Query: 676 PPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG 735
P PG P PP LP + P G PPPPP PPPPP P
Sbjct: 1000 GAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPP------PPPPPPAPAS 1053
Query: 736 PGIPPPPPGMGMP----PPPPFGFGVPAAPVL----PFGLTPKKLYKPEVQ 778
P G+ P P + +L P TPKKLY E +
Sbjct: 1054 ----EPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYE 1100
Score = 45.1 bits (105), Expect = 4e-04
Identities = 58/200 (29%), Positives = 64/200 (32%), Gaps = 51/200 (25%)
Query: 601 APGDSTTPPPPPPPPPPPPPLPGGVCI------SSPPSLPGGTAISPPPPLSGDATIPPP 654
A G +T PPPP P GG +S GG A SP P + P
Sbjct: 399 AAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQG----LLGP 454
Query: 655 PPLPEGVG------IPSPSSLPGGTAIPPP-PPLPGSARI-----------------PPP 690
+G G + S GG PP PP PG A P
Sbjct: 455 QAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPY 514
Query: 691 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP--------- 741
P P S G+P P L G P GG G P GG G P
Sbjct: 515 PGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWG----PSSLGGGGEASPSHIIRPLQS 570
Query: 742 PPGMGMPPPPPFGFGVPAAP 761
PP G PP G G P AP
Sbjct: 571 PPATGRPP----GVGSPGAP 586
Score = 43.5 bits (101), Expect = 0.001
Identities = 21/58 (36%), Positives = 25/58 (43%)
Query: 586 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPP 643
PP+P P + G S+ PPP P PPP P P PP TA+ PP
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
Score = 41.6 bits (96), Expect = 0.005
Identities = 52/189 (27%), Positives = 62/189 (32%), Gaps = 29/189 (15%)
Query: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV-----CI 627
PP +PS P + PPPP PPPPPPP P P GG+ C
Sbjct: 1015 PPELPSTVNAEPLGLIQSGPHQAAPPPP-------PPPPPPPAPASEP-KGGLTSPIFCS 1066
Query: 628 SSPPSLPGGTAI----SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP--PPL 681
+ P L ++ PP + E + +P + P P L
Sbjct: 1067 TKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQE--YEFEADEDKADVPADIRLNPRRLPDL 1124
Query: 682 PGSARIPPPPPPLPGSAGIPP-PPPPLPGEAGMPPP------PPPLPGGPGIPP-PPPFP 733
S R P PL PP P P P G P PP G P I P P
Sbjct: 1125 VSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTT 1184
Query: 734 GGPGIPPPP 742
GP P
Sbjct: 1185 AGPASASTP 1193
Score = 40.8 bits (94), Expect = 0.008
Identities = 50/175 (28%), Positives = 60/175 (34%), Gaps = 39/175 (22%)
Query: 602 PGDSTTPPP--------PPPPPPPPPPLPGGVCISSPP-SLPGGTAISPPPPLSGDATIP 652
PG ST P P P P+P + + PP S P +SP L +
Sbjct: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQA 196
Query: 653 PPPPLPEGV------GIPSPSSLPGGTAIPPPPPLPGSARIPPPPPP---LP-------- 695
P P G G+ P+ L G PP P P P PPPP LP
Sbjct: 197 PTVPSSLGFERLAGGGVLGPAGL-GPAQTPPYRPGP-----PDPPPPPRHLPTQFNLLAS 250
Query: 696 ---GSAGIPPPPPPLPGEAGMPPPPPP----LPGGPGIPPPPPFPGGPGIPPPPP 743
+A P L +G P PPP LP + P PPPPP
Sbjct: 251 SSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPP 305
Score = 40.4 bits (93), Expect = 0.011
Identities = 32/99 (32%), Positives = 38/99 (38%), Gaps = 21/99 (21%)
Query: 583 PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP----PPPPPPPLPGGVCISSPPSLPGGTA 638
PP PP G P PG ++ P P P PP LP V + G
Sbjct: 981 PPGPPAYDPYG-----PYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPH 1035
Query: 639 ISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP 677
+ PPP PPPPP P P+P+S P G P
Sbjct: 1036 QAAPPP-------PPPPPPP-----PAPASEPKGGLTSP 1062
Score = 40.4 bits (93), Expect = 0.011
Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 7/67 (10%)
Query: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 712
PP P+ +P S G +A PP P PPP P P PP P E
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPA------PPPKPETPEKTTSEKPPEQTP-ETA 1722
Query: 713 MPPPPPP 719
MP PP P
Sbjct: 1723 MPEPPAP 1729
Score = 37.0 bits (84), Expect = 0.12
Identities = 47/156 (30%), Positives = 50/156 (32%), Gaps = 33/156 (21%)
Query: 601 APGDSTTPPPPPPPPPPPPPLPGGVCIS-SPPSLPGGTAISPPPPLSGDATIPPPPPLPE 659
AP S PP PP PPPP C S SP L G L G P P P
Sbjct: 472 APSYSGGPPQPPSGPPPPGL---ATCQSYSPDQLQG--------QLYGVQGEPYPGPAAH 520
Query: 660 GVGIPSPS-SLPGGTAIPP----------PPPLPGSARIPPPPPPLPGSAGIPPPPPPLP 708
G+P+ S SL T P P L G P P PP
Sbjct: 521 SQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEAS------PSHIIRPLQSPPAT 574
Query: 709 GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPG 744
G PP PG PG P + PP G
Sbjct: 575 GR----PPGVGSPGAPGKYLSSVLASAPFLAPPGAG 606
Score = 36.6 bits (83), Expect = 0.16
Identities = 30/114 (26%), Positives = 40/114 (35%), Gaps = 22/114 (19%)
Query: 652 PPPPPLPEGVGIPSPSSLPGGTAIPP----------PPPLPGSARIPPPPPPLPGSAGIP 701
P P L +P S+ P +A+ P P+P S + PP P + +
Sbjct: 125 PGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLS 184
Query: 702 PPPPPLPGEAGMPPPPPPL------------PGGPGIPPPPPFPGGPGIPPPPP 743
P + P P L P G G PP+ GP PPPPP
Sbjct: 185 PHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPP 238
Score = 35.4 bits (80), Expect = 0.35
Identities = 31/100 (31%), Positives = 37/100 (37%), Gaps = 16/100 (16%)
Query: 685 ARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP-- 742
AR P PP+P P G + PPP P P PP P P PP
Sbjct: 1663 ARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAP-----PPKPETPEKTTSEKPPEQ 1717
Query: 743 -PGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRR 781
P MP PP AP P L P + K + ++ R
Sbjct: 1718 TPETAMPEPP--------APEKPSLLRPVEKEKEKEKVTR 1749
Score = 33.1 bits (74), Expect = 1.7
Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP 616
+SA + PP +AP PP P + T PP ++ P PP P P
Sbjct: 1684 VSAGGSSAPPP---KAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKP 1732
Score = 32.0 bits (71), Expect = 3.9
Identities = 24/87 (27%), Positives = 29/87 (33%), Gaps = 18/87 (20%)
Query: 625 VCISSP---PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 681
VC P P +P + P+S + PPP P A PP P
Sbjct: 1661 VCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAP---------------APPPKPET 1705
Query: 682 PGSARIPPPPPPLPGSAGIPPPPPPLP 708
P PP P +A PP P P
Sbjct: 1706 PEKTTSEKPPEQTPETAMPEPPAPEKP 1732
Score = 31.2 bits (69), Expect = 6.6
Identities = 19/64 (29%), Positives = 22/64 (34%), Gaps = 6/64 (9%)
Query: 679 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGI 738
PP+P P G + PPP P PPP P P PP +
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAP------APPPKPETPEKTTSEKPPEQTPETAM 1723
Query: 739 PPPP 742
P PP
Sbjct: 1724 PEPP 1727
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 108 bits (270), Expect = 3e-23
Identities = 85/231 (36%), Positives = 90/231 (38%), Gaps = 38/231 (16%)
Query: 577 PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP--------PPPPPPPPPPLPGGVCIS 628
PS P P P PPP PG PPP PPPP P P P G
Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
Query: 629 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 688
SP S PG PPP G+ PPPP + G P P G P PP PG + P
Sbjct: 89 SPRSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPP-----PQGGNRPQGPPPPGKPQGP 141
Query: 689 PPPPPLPGSAGIPPPPP--PLPGEAGMPPPPPPLPGGPGIPPP--------PPFPGGPGI 738
PP S PP P P P P PPP PG P PPP PP PG P
Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG 201
Query: 739 PPP----------PPGMGMPPPPPFG---FGVPAAPVLPFGLTPKKLYKPE 776
PPP PPG PPP G G P P P G P+ KP+
Sbjct: 202 PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252
Score = 107 bits (267), Expect = 7e-23
Identities = 82/219 (37%), Positives = 87/219 (39%), Gaps = 41/219 (18%)
Query: 573 PPSVPSRAPV-----PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCI 627
PP P P P PP PG PP GD + P PP P PP GG
Sbjct: 53 PPGKPQGPPPQGGNKPQGPPPPGKP----QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 108
Query: 628 SSPPSLPGGTAISPPPPLSGDATIPPPPP------LPEGVGIPSPSSLPGGTAIPPPPPL 681
PP PG PPP G+ PPPP P+G SP S PG PPP
Sbjct: 109 QGPPPPPGKP--QGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ--GPPPQ 164
Query: 682 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP--------------GIP 727
G+ PPPPP G P PPP G+ PPPP P GP G P
Sbjct: 165 GGNQPQGPPPPP-----GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219
Query: 728 PPPPFPGG--PGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764
PP GG P PPPPPG PPP G P P P
Sbjct: 220 QGPPPQGGNQPQGPPPPPGKPQGPPPQ-GGNKPQGPPPP 257
Score = 97.4 bits (241), Expect = 7e-20
Identities = 80/238 (33%), Positives = 85/238 (35%), Gaps = 57/238 (23%)
Query: 577 PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP--------PPPPPPPPPPLPGGVCIS 628
P P P P P PPP PG PPP PPPP P P P G
Sbjct: 90 PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSR 149
Query: 629 SPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIP 688
SP S PG PPP G+ PPPP + G P P G P PP PG + P
Sbjct: 150 SPRSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPP-----PQGGKKPQGPPPPGKPQGP 202
Query: 689 PP-----------------PPPLPGSAGIPPPPPP-----LPGEAGMPPPPPPLPGGPGI 726
PP PPP G+ PPPPP P + G P PP PG P
Sbjct: 203 PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 262
Query: 727 PP------------PPPFPGGPGI--------PPPPPGMGMPPPPPFGFGVPAAPVLP 764
PP PP P GP PPPP G P G P P P
Sbjct: 263 PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 320
Score = 92.8 bits (229), Expect = 2e-18
Identities = 67/184 (36%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPS 632
PP P P PP G PPP PPPP P PPP SPP
Sbjct: 161 PPPQGGNQPQGPPPPPGKPQG---PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG 217
Query: 633 LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPP 692
P G PPP G+ PPPP + G P P G P PP PG + PP
Sbjct: 218 KPQG-----PPPQGGNQPQGPPPPPGKPQGPP-----PQGGNKPQGPPPPGKPQGPPAQG 267
Query: 693 PLPGSAGIPPPPPPL--PGEAGMPP--PPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMP 748
+ PP P P + G P PPPP G P P PP G P PP PP G P
Sbjct: 268 GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP-AGQPQGPPRPPQGGRP 326
Query: 749 PPPP 752
PP
Sbjct: 327 SRPP 330
Score = 63.5 bits (153), Expect = 1e-09
Identities = 55/168 (32%), Positives = 59/168 (35%), Gaps = 60/168 (35%)
Query: 665 SPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP-------PPLPGEAGMPPP- 716
SPS + G P P P P PPP PG PPP PP PG+ PPP
Sbjct: 28 SPSLIAGN----PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
Query: 717 ---------------------------PPPLPGGPGIPPP--------PPFPGGPGIPPP 741
PPP PG P PPP PP PG P PPP
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP 143
Query: 742 ----------PPGMGMPPPPPFG---FGVPAAPVLPFGLTPKKLYKPE 776
PPG PPP G G P P P G P+ KP+
Sbjct: 144 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQ 191
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 108 bits (269), Expect = 4e-23
Identities = 76/210 (36%), Positives = 80/210 (38%), Gaps = 42/210 (20%)
Query: 568 AAITVPPSVPSRAPVPPA---------PPLPGDSGTIIPPPPAPGDST------------ 606
AA T PP AP PP PPLP S P PG T
Sbjct: 161 AARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP 220
Query: 607 --TPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP 664
PPPPPPPPP PPPLP +S P + PP IPPP PL G P
Sbjct: 221 CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP-------IPPPLPLLPPCGYP 273
Query: 665 SPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP----PPPPLPGEAGMPPPPPPL 720
G P P + P PPPPLP A P P PPLPG PPPL
Sbjct: 274 -------GLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPL 326
Query: 721 -PGGPGIPPPPPFPGGPGIPPPPPGMGMPP 749
P P PP G +P PP G P
Sbjct: 327 PPKSPSFQAPPQKAGAQALPAPPAPPGSQP 356
Score = 102 bits (253), Expect = 3e-21
Identities = 80/231 (34%), Positives = 100/231 (43%), Gaps = 50/231 (21%)
Query: 572 VPPSVPSRAPVPPAPPLPGDS----GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCI 627
+P S +PPA P G++ G PP P + PPPP PPPPPPPLP +
Sbjct: 135 LPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRP--NVPAPPPPTPPPPPPPLPPPLPS 192
Query: 628 SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 687
SSP P +SPP PL+ PP+P A PPPPP P
Sbjct: 193 SSPIKTP---LVSPPGPLTKGNLPVVAPPVP--------------CAPPPPPPPP----- 230
Query: 688 PPPPPPLPGSA-----GIPPPPPPLPGEAGMPPPPPPLP-----GGPGIPPPPPFPGGPG 737
PP PPPLP ++ + P PL +PP PPPLP G PG+ P P
Sbjct: 231 PPTPPPLPPASVLSDKAVKPQLAPLH----LPPIPPPLPLLPPCGYPGLKAEPASPAQDA 286
Query: 738 IPPPPPGMGMPPPPPFGFGVP----AAPVLPFGLTPKKLYKPEVQLRRPNW 784
PP P PP PP+ P AP LP G+ P + + P++
Sbjct: 287 QEPPAPP---PPLPPYASCSPRASLPAPPLP-GVNSSSETPPPLPPKSPSF 333
Score = 79.3 bits (194), Expect = 2e-14
Identities = 64/195 (32%), Positives = 71/195 (36%), Gaps = 31/195 (15%)
Query: 564 SLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP--PPPPPPPL 621
+L A VP + P P PP P P +PP D P P PP PPPL
Sbjct: 211 NLPVVAPPVPCAPPPPPPPPPPTPPP------LPPASVLSDKAVKPQLAPLHLPPIPPPL 264
Query: 622 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 681
P + P PG A P PPPPLP +SLP PPL
Sbjct: 265 P----LLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPA-------PPL 313
Query: 682 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPP--------PPPFP 733
PG PPPLP + PP G +P PP P PG P P
Sbjct: 314 PGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAP----PGSQPFLQKKRHGRPGAG 369
Query: 734 GGPGIPPPPPGMGMP 748
GG PPP P P
Sbjct: 370 GGKLNPPPAPPARSP 384
Score = 77.0 bits (188), Expect = 1e-13
Identities = 81/259 (31%), Positives = 93/259 (35%), Gaps = 93/259 (35%)
Query: 581 PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPL------PGG---------- 624
PVPP PP P +PPPP P + PPPP PP P G
Sbjct: 2 PVPPPPPPP------LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55
Query: 625 ---------VCISSPPSLP---------GGTAI---SPPPPLSGDATIPPPPPL------ 657
+ S P + GG+A + PP GD P L
Sbjct: 56 GTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR 115
Query: 658 -------PEGVGIPSPS-SLP----GGTAIPPPPP-------LPGSARIPPPPPPLPGSA 698
+G G +PS LP G IPP P G+AR PP P +P
Sbjct: 116 DVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPP 175
Query: 699 GIPPPPPPLPGEAGMPPPPPPLPGG-----PGIPPPPPFPGG---------PGIPPPPPG 744
PPPPP PP PPPLP P + PP P G P PPPPP
Sbjct: 176 PPTPPPPP-------PPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP- 227
Query: 745 MGMPPPPPFGFGVPAAPVL 763
PPPPP +P A VL
Sbjct: 228 ---PPPPPTPPPLPPASVL 243
Score = 70.9 bits (172), Expect = 8e-12
Identities = 64/187 (34%), Positives = 74/187 (39%), Gaps = 37/187 (19%)
Query: 599 PPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP--PP 656
PP GD P P + GG P G A SP P + TI P PP
Sbjct: 95 PPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGP----GSRAPSPRLP---NKTISGPLIPP 147
Query: 657 LPEGVGIPSPSSLPGGTAIP------PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE 710
+G S + TA P PPPP P PPPPPPLP PP P P +
Sbjct: 148 ASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP-----PPPPPPLP-----PPLPSSSPIK 197
Query: 711 AGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPK 770
+ PP PL G PP P P PPPPP PP PP P+ P +
Sbjct: 198 TPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP----PPTPP--------PLPPASVLSD 245
Query: 771 KLYKPEV 777
K KP++
Sbjct: 246 KAVKPQL 252
Score = 42.0 bits (97), Expect = 0.004
Identities = 34/114 (29%), Positives = 42/114 (36%), Gaps = 26/114 (22%)
Query: 573 PPSVPSRAPVPP-----APPLPGDSGTIIPPPPAP-------------GDSTTPPPPPPP 614
PP +P A P APPLPG + + PPP P G P PP PP
Sbjct: 293 PPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPP 352
Query: 615 PPPP--------PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 660
P P GG ++ PP+ P + + S AT P P G
Sbjct: 353 GSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGG 406
Score = 35.0 bits (79), Expect = 0.46
Identities = 14/27 (51%), Positives = 15/27 (55%)
Query: 738 IPPPPPGMGMPPPPPFGFGVPAAPVLP 764
+PPPPP PPPPP G P P P
Sbjct: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAP 29
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 108 bits (269), Expect = 4e-23
Identities = 81/208 (38%), Positives = 90/208 (43%), Gaps = 36/208 (17%)
Query: 578 SRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP--PPP--PPPLPGGVCISSPPSL 633
+R P+ P P G I PPPP PP PPP PPP PPP P PP
Sbjct: 43 NRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPP 102
Query: 634 PGGTA----ISPPPPLSGDATIPP-----PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGS 684
P ++ P P G + PP PP P G P P S PG P P P P
Sbjct: 103 PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAP-PGSGPG----PTPTPPPAV 157
Query: 685 ARIPP-PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGI-PPPPPFPGG------P 736
PP PPP P S+G+P PP +AG PPPPP GPG P P PGG P
Sbjct: 158 TSAPPGAPPPTPPSSGVPTTPP----QAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMP 213
Query: 737 GIPPPPPGMGM------PPPPPFGFGVP 758
G P P G G+ P PP G G P
Sbjct: 214 GGPKPGGGPGLSTPGGHPKPPHRGGGEP 241
Score = 97.8 bits (242), Expect = 6e-20
Identities = 76/222 (34%), Positives = 86/222 (38%), Gaps = 44/222 (19%)
Query: 574 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP---------PPPPPPLPGG 624
P P PP PP P PPP P PP PPP PPPPP
Sbjct: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108
Query: 625 VCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGI-PSPSSLPGGTAIPP--PPPL 681
++ P G +PP S PP P G G P+P+ P T+ PP PPP
Sbjct: 109 PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPT 168
Query: 682 PGSARIPPPPPPLPGSAGIPPPPP-------------PLPG--EAGMPPPPPPLPGGPGI 726
P S+ +P PP AG PPPPP P PG + G P P GGPG+
Sbjct: 169 PPSSGVPTTPP----QAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGL 224
Query: 727 P-----PPPPFPGGPGIP-------PPPPGMGMPPPPPFGFG 756
P PP GG G P PP PPP G G
Sbjct: 225 STPGGHPKPPHRGG-GEPRGGRQHHPPYHQQHHQGPPPGGPG 265
Score = 81.6 bits (200), Expect = 4e-15
Identities = 58/163 (35%), Positives = 65/163 (39%), Gaps = 35/163 (21%)
Query: 617 PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP--SPSSLPGGTA 674
PPP + G+ + P PG P PP IPPPPP + P P
Sbjct: 34 PPPGM--GLNQNRGPMGPGPGQSGPKPP------IPPPPPHQQQQQPPPQQPPPQQPPPH 85
Query: 675 IPPPPPLPGSARIPPPPP-------------PLPGSAGIPP----PPPPLPGEAGMP--- 714
PPP P P + PPPPP P PG PP PP P +G P
Sbjct: 86 QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145
Query: 715 ---PPPPPLPGGPGIPP--PPPFPGGPGIPPPPPGMGMPPPPP 752
P P P P PP PPP P G+P PP G PPPPP
Sbjct: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
Score = 71.2 bits (173), Expect = 6e-12
Identities = 54/162 (33%), Positives = 59/162 (36%), Gaps = 40/162 (24%)
Query: 640 SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 699
SPPP + + P P P G P IPPPPP + PP PP
Sbjct: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPP--------IPPPPPHQQQQQPPPQQPPPQQPPP 84
Query: 700 IPPPPPPLPGEAGMPPPPP-------------PLPGGPGIPP-----PPPFPGGPGIPP- 740
PPP P P + PPPPP P PG PP PP P G PP
Sbjct: 85 HQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG 144
Query: 741 --------PPPGM-----GMPPPPPFGFGVPAAPVLPFGLTP 769
PPP + G PPP P GVP P G P
Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPP 186
Score = 70.9 bits (172), Expect = 8e-12
Identities = 64/188 (34%), Positives = 75/188 (39%), Gaps = 45/188 (23%)
Query: 556 EDAKKEMASLSAAAITVPPSVPSRAPVPPA-PPLPGDSGTIIPPPPAPGDSTTPPPP--- 611
+ +K +A A V + P+ + PPA PP G PP PG + TPPP
Sbjct: 105 DSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG-----APPGSGPGPTPTPPPAVTS 159
Query: 612 -PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE---GVGIPSPS 667
PP PPP P GV P+ P PPPP A +P P P P+ G G P
Sbjct: 160 APPGAPPPTPPSSGV-----PTTPPQAGGPPPPP----AAVPGPGPGPKQGPGPGGPKGG 210
Query: 668 SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE--AGMPPPPP------- 718
+PGG P PG P L G P PP GE G PP
Sbjct: 211 KMPGG-------PKPGGG------PGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQ 257
Query: 719 -PLPGGPG 725
P PGGPG
Sbjct: 258 GPPPGGPG 265
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,317,609
Number of Sequences: 37866
Number of extensions: 5257755
Number of successful extensions: 192255
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1768
Number of HSP's successfully gapped in prelim test: 2338
Number of HSP's that attempted gapping in prelim test: 33044
Number of HSP's gapped (non-prelim): 47133
length of query: 1272
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1158
effective length of database: 13,930,794
effective search space: 16131859452
effective search space used: 16131859452
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.