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Search of human proteins with 239756740
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239756740 PREDICTED: similar to CMT1A duplicated region
transcript 1 [Homo sapiens]
(433 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756740 PREDICTED: similar to CMT1A duplicated region trans... 894 0.0
gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens] 761 0.0
gi|157694487 CMT1A duplicated region transcript 1 [Homo sapiens] 758 0.0
gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens] 40 0.004
gi|27312027 F-box only protein 16 [Homo sapiens] 35 0.13
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 33 0.39
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 32 0.86
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 32 1.5
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 32 1.5
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 32 1.5
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H... 32 1.5
gi|41152506 prostaglandin F2 receptor negative regulator [Homo s... 32 1.5
gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] 30 3.3
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 30 4.3
gi|13569840 MACRO domain containing 1 [Homo sapiens] 30 5.6
gi|239746772 PREDICTED: similar to hCG1981372 [Homo sapiens] 29 7.3
>gi|239756740 PREDICTED: similar to CMT1A duplicated region
transcript 1 [Homo sapiens]
Length = 433
Score = 894 bits (2309), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MIMENLESRLKNAPYFRCEKGTDSNPLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLV 60
MIMENLESRLKNAPYFRCEKGTDSNPLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLV
Sbjct: 1 MIMENLESRLKNAPYFRCEKGTDSNPLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLV 60
Query: 61 GILKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKM 120
GILKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKM
Sbjct: 61 GILKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKM 120
Query: 121 KEILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVC 180
KEILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVC
Sbjct: 121 KEILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVC 180
Query: 181 FSPEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHFLGAASNPEEPWRNSLRCISEMN 240
FSPEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHFLGAASNPEEPWRNSLRCISEMN
Sbjct: 181 FSPEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHFLGAASNPEEPWRNSLRCISEMN 240
Query: 241 RLFSGKADITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTL 300
RLFSGKADITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTL
Sbjct: 241 RLFSGKADITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTL 300
Query: 301 NKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDD 360
NKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDD
Sbjct: 301 NKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDD 360
Query: 361 GKSMRVKHPKWKLRTKPLAVFCVHGTRSFSGKFRGQEQPHQPMPLEDPASAAQEFEEDPR 420
GKSMRVKHPKWKLRTKPLAVFCVHGTRSFSGKFRGQEQPHQPMPLEDPASAAQEFEEDPR
Sbjct: 361 GKSMRVKHPKWKLRTKPLAVFCVHGTRSFSGKFRGQEQPHQPMPLEDPASAAQEFEEDPR 420
Query: 421 GGPGLVPECLGPR 433
GGPGLVPECLGPR
Sbjct: 421 GGPGLVPECLGPR 433
>gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens]
Length = 1051
Score = 761 bits (1965), Expect = 0.0
Identities = 371/374 (99%), Positives = 371/374 (99%)
Query: 3 MENLESRLKNAPYFRCEKGTDSNPLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGI 62
MENLESRLKNAPYFRCEKGTDS PLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGI
Sbjct: 1 MENLESRLKNAPYFRCEKGTDSIPLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGI 60
Query: 63 LKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKE 122
LKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKE
Sbjct: 61 LKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKE 120
Query: 123 ILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVCFS 182
ILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVCFS
Sbjct: 121 ILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVCFS 180
Query: 183 PEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHFLGAASNPEEPWRNSLRCISEMNRL 242
PEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEH LGAASNPEEPWRNSLRCISEMNRL
Sbjct: 181 PEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHLLGAASNPEEPWRNSLRCISEMNRL 240
Query: 243 FSGKADITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTLNK 302
FSGK DITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTLNK
Sbjct: 241 FSGKGDITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTLNK 300
Query: 303 CASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDDGK 362
CASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDDGK
Sbjct: 301 CASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDDGK 360
Query: 363 SMRVKHPKWKLRTK 376
SMRVKHPKWKLRTK
Sbjct: 361 SMRVKHPKWKLRTK 374
>gi|157694487 CMT1A duplicated region transcript 1 [Homo sapiens]
Length = 752
Score = 758 bits (1958), Expect = 0.0
Identities = 371/374 (99%), Positives = 372/374 (99%)
Query: 3 MENLESRLKNAPYFRCEKGTDSNPLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGI 62
MENLESRLKNAPYFRCEKGTDS PLCRKCET VLAWKIFSTKEWFCRINDISQRRFLVGI
Sbjct: 1 MENLESRLKNAPYFRCEKGTDSIPLCRKCETRVLAWKIFSTKEWFCRINDISQRRFLVGI 60
Query: 63 LKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKE 122
LKQLNSLYLLHYFQNILQTTQGKDFIYNRSRI+LSKKEGKVVKSSLNQMLDKTVEQKMKE
Sbjct: 61 LKQLNSLYLLHYFQNILQTTQGKDFIYNRSRIDLSKKEGKVVKSSLNQMLDKTVEQKMKE 120
Query: 123 ILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVCFS 182
ILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVCFS
Sbjct: 121 ILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVCFS 180
Query: 183 PEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHFLGAASNPEEPWRNSLRCISEMNRL 242
PEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHFLGAASNPEEPWRNSLRCISEMNRL
Sbjct: 181 PEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHFLGAASNPEEPWRNSLRCISEMNRL 240
Query: 243 FSGKADITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTLNK 302
FSGKADITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTLNK
Sbjct: 241 FSGKADITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTLNK 300
Query: 303 CASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDDGK 362
CASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDDGK
Sbjct: 301 CASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANKVSIPVPKMVDDGK 360
Query: 363 SMRVKHPKWKLRTK 376
SMRVKHPKWKLRTK
Sbjct: 361 SMRVKHPKWKLRTK 374
>gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens]
Length = 454
Score = 40.0 bits (92), Expect = 0.004
Identities = 17/34 (50%), Positives = 23/34 (67%)
Query: 277 RDFIRYLPIHLSKYILRMLDRHTLNKCASVSQHW 310
RDF++ LP+ LS Y+L+ LD TL C VS+ W
Sbjct: 54 RDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQW 87
>gi|27312027 F-box only protein 16 [Homo sapiens]
Length = 292
Score = 35.0 bits (79), Expect = 0.13
Identities = 17/38 (44%), Positives = 21/38 (55%)
Query: 278 DFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQ 315
DF LP LS YI LD +L +CA V HW +A+
Sbjct: 87 DFTTKLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLAE 124
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 33.5 bits (75), Expect = 0.39
Identities = 26/105 (24%), Positives = 53/105 (50%), Gaps = 6/105 (5%)
Query: 72 LHYFQNILQTTQGKDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKEILYWFANST 131
L Y Q+++ T G+ F R R ++ +V ++ML+K ++++ ++ + +T
Sbjct: 153 LDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPAT 212
Query: 132 QWTKANYTL--LLLQMCNPKLLLTAANVIRVLFLREENNISGLNQ 174
Q + TL +L+M N + + IR+L R+E + G+ Q
Sbjct: 213 QVVLISATLPHEILEMTNKFM----TDPIRILVKRDELTLEGIKQ 253
>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
sapiens]
Length = 598
Score = 32.3 bits (72), Expect = 0.86
Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 7/57 (12%)
Query: 259 LLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQ 315
L+ DL+++ D+ F LP L+ I + LDR L +CA VS+ W +A+
Sbjct: 102 LIRDLNEMNDVPF-------FDIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAE 151
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 31.6 bits (70), Expect = 1.5
Identities = 14/39 (35%), Positives = 22/39 (56%)
Query: 277 RDFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQ 315
RDFI LP L+ Y+L L+ L + A ++W +A+
Sbjct: 160 RDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAE 198
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 31.6 bits (70), Expect = 1.5
Identities = 14/39 (35%), Positives = 22/39 (56%)
Query: 277 RDFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQ 315
RDFI LP L+ Y+L L+ L + A ++W +A+
Sbjct: 278 RDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAE 316
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 31.6 bits (70), Expect = 1.5
Identities = 14/39 (35%), Positives = 22/39 (56%)
Query: 277 RDFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQ 315
RDFI LP L+ Y+L L+ L + A ++W +A+
Sbjct: 198 RDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAE 236
>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
sapiens]
Length = 532
Score = 31.6 bits (70), Expect = 1.5
Identities = 14/33 (42%), Positives = 20/33 (60%)
Query: 283 LPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQ 315
LP L+ I + LDR L +CA VS+ W +A+
Sbjct: 53 LPYELAINIFQYLDRKELGRCAQVSKTWKVIAE 85
>gi|41152506 prostaglandin F2 receptor negative regulator [Homo
sapiens]
Length = 879
Score = 31.6 bits (70), Expect = 1.5
Identities = 44/217 (20%), Positives = 79/217 (36%), Gaps = 36/217 (16%)
Query: 28 CRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGILKQLNSLYLLHYFQNILQTTQGKDF 87
CR +T + T W+ R+N S +L ++ + L Y + Q Q DF
Sbjct: 429 CRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDF 488
Query: 88 IYNRS-------RINLSKKEGK-----VVKSSLNQMLDKTVEQK---MKEI-LYWFANST 131
I+++ RI + +E + VV + Q + V+ K K + ++W
Sbjct: 489 IFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNIFWALED- 547
Query: 132 QWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVCFSPEKDHSSKS 191
++L+++ PK A N + NI + + P D SS +
Sbjct: 548 -------SVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPN 600
Query: 192 ATSQVY------------WTAKTQHTSLPLSKAPENE 216
T + WT ++ + L K E+E
Sbjct: 601 ETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDE 637
>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
Length = 335
Score = 30.4 bits (67), Expect = 3.3
Identities = 26/113 (23%), Positives = 41/113 (36%), Gaps = 21/113 (18%)
Query: 26 PLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGILKQLNSLYLLHYFQNILQTTQGK 85
P+C E CV + + F K W + + Y + + LQT
Sbjct: 18 PVCGAAELCVNSLEKFHFKSW----------------MSKHRKTYSTEEYHHRLQT---- 57
Query: 86 DFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKEILYWFANSTQWTKANY 138
F N +IN K +LNQ D + + + L+ + TK+NY
Sbjct: 58 -FASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNY 109
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 30.0 bits (66), Expect = 4.3
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 10/99 (10%)
Query: 77 NILQTTQGK--DFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKEILYWFANSTQWT 134
+IL T G+ D ++N +LS E ++ + ++MLD+ E++MKEI+ ++ Q
Sbjct: 341 DILIATPGRLIDHLHNCPSFHLSSIEVLILDEA-DRMLDEYFEEQMKEIIRMCSHHRQTM 399
Query: 135 KANYT-------LLLLQMCNPKLLLTAANVIRVLFLREE 166
+ T L + + NP + +N FLR+E
Sbjct: 400 LFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQE 438
>gi|13569840 MACRO domain containing 1 [Homo sapiens]
Length = 325
Score = 29.6 bits (65), Expect = 5.6
Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Query: 310 WAAMAQQVKMDLSAHGFIQNQITFLQGSYTRGIDPNYANK-----VSIPVPKMVDDGKSM 364
WA +A K+DLS + +FL+G + + +Y K IP K + G ++
Sbjct: 78 WAPLAMAAKVDLSTSTDWKEAKSFLKGLSDKQREEHYFCKDFVRLKKIPTWKEMAKGVAV 137
Query: 365 RVKHPKWK 372
+V+ P++K
Sbjct: 138 KVEEPRYK 145
>gi|239746772 PREDICTED: similar to hCG1981372 [Homo sapiens]
Length = 317
Score = 29.3 bits (64), Expect = 7.3
Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 5/51 (9%)
Query: 376 KPLAVFCVHGTRSFSGKFRGQEQPHQPMPLEDPASAAQEFEEDPRGGPGLV 426
K L CV T SG+ +GQE+P + P SA Q + PRG LV
Sbjct: 231 KQLEAICVKVT---SGETKGQERPTSLLATVQPQSARQ--SQPPRGNSRLV 276
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,977,909
Number of Sequences: 37866
Number of extensions: 762373
Number of successful extensions: 2283
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2268
Number of HSP's gapped (non-prelim): 20
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.