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Search of human proteins with 239756693
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239756693 PREDICTED: similar to coiled-coil domain
containing 92 [Homo sapiens]
(272 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756693 PREDICTED: similar to coiled-coil domain containing... 538 e-153
gi|169211642 PREDICTED: hypothetical protein [Homo sapiens] 402 e-112
gi|169210857 PREDICTED: similar to RIKEN cDNA E130309D14 [Homo s... 402 e-112
gi|13376725 coiled-coil domain containing 92 [Homo sapiens] 113 2e-25
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 57 2e-08
gi|13994287 BTE-binding protein 4 [Homo sapiens] 49 4e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 47 2e-05
gi|157042792 coiled-coil domain containing 64B [Homo sapiens] 43 3e-04
gi|169163019 PREDICTED: hypothetical protein [Homo sapiens] 43 3e-04
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens] 43 3e-04
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens] 43 3e-04
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens] 42 4e-04
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens] 42 4e-04
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ... 42 6e-04
gi|169163728 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04
gi|169163708 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04
gi|239744552 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ... 42 6e-04
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens] 42 6e-04
gi|61966741 TMF regulated nuclear protein [Homo sapiens] 42 6e-04
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 42 7e-04
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 41 0.001
gi|49472835 bridging integrator 2 [Homo sapiens] 41 0.001
gi|169206489 PREDICTED: hypothetical protein [Homo sapiens] 41 0.001
gi|169205942 PREDICTED: hypothetical protein [Homo sapiens] 41 0.001
gi|210031154 zinc finger protein 541 [Homo sapiens] 41 0.001
gi|222446647 coiled-coil domain containing 153 [Homo sapiens] 40 0.002
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] 40 0.002
gi|46852390 coiled-coil domain containing 6 [Homo sapiens] 40 0.002
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 40 0.003
>gi|239756693 PREDICTED: similar to coiled-coil domain containing 92
[Homo sapiens]
Length = 272
Score = 538 bits (1386), Expect = e-153
Identities = 272/272 (100%), Positives = 272/272 (100%)
Query: 1 MKTYGFARKPGGAQAWVAMDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRC 60
MKTYGFARKPGGAQAWVAMDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRC
Sbjct: 1 MKTYGFARKPGGAQAWVAMDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRC 60
Query: 61 SEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERRFLEELRR 120
SEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERRFLEELRR
Sbjct: 61 SEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERRFLEELRR 120
Query: 121 RSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLAG 180
RSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLAG
Sbjct: 121 RSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLAG 180
Query: 181 VTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSP 240
VTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSP
Sbjct: 181 VTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSP 240
Query: 241 LLAREFLRGAERGHLLYREDSPSRSWPGPTCL 272
LLAREFLRGAERGHLLYREDSPSRSWPGPTCL
Sbjct: 241 LLAREFLRGAERGHLLYREDSPSRSWPGPTCL 272
>gi|169211642 PREDICTED: hypothetical protein [Homo sapiens]
Length = 378
Score = 402 bits (1033), Expect = e-112
Identities = 212/240 (88%), Positives = 214/240 (89%), Gaps = 18/240 (7%)
Query: 51 LEILRLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE 110
LE+ Q EAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE
Sbjct: 139 LEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE 198
Query: 111 ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQA-----PRPGPA---- 161
ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQA P+P PA
Sbjct: 199 ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQRPQPAPAASPG 258
Query: 162 ---------RAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRK 212
RAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRK
Sbjct: 259 APGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRK 318
Query: 213 RGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSWPGPTCL 272
RGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSWPGPTCL
Sbjct: 319 RGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSWPGPTCL 378
Score = 86.7 bits (213), Expect = 2e-17
Identities = 43/43 (100%), Positives = 43/43 (100%)
Query: 19 MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS 61
MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS
Sbjct: 1 MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS 43
>gi|169210857 PREDICTED: similar to RIKEN cDNA E130309D14 [Homo
sapiens]
Length = 378
Score = 402 bits (1033), Expect = e-112
Identities = 212/240 (88%), Positives = 214/240 (89%), Gaps = 18/240 (7%)
Query: 51 LEILRLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE 110
LE+ Q EAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE
Sbjct: 139 LEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE 198
Query: 111 ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQA-----PRPGPA---- 161
ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQA P+P PA
Sbjct: 199 ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQRPQPAPAASPG 258
Query: 162 ---------RAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRK 212
RAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRK
Sbjct: 259 APGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRK 318
Query: 213 RGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSWPGPTCL 272
RGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSWPGPTCL
Sbjct: 319 RGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSWPGPTCL 378
Score = 86.7 bits (213), Expect = 2e-17
Identities = 43/43 (100%), Positives = 43/43 (100%)
Query: 19 MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS 61
MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS
Sbjct: 1 MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS 43
>gi|13376725 coiled-coil domain containing 92 [Homo sapiens]
Length = 331
Score = 113 bits (283), Expect = 2e-25
Identities = 58/167 (34%), Positives = 104/167 (62%), Gaps = 18/167 (10%)
Query: 17 VAMDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSE-------------- 62
V+M +LE+Q+ S Q+++ FL++E + L+ LH EI RLQ+ C++
Sbjct: 16 VSMAATNLENQLHSAQKNLLFLQREHASTLKGLHSEIRRLQQHCTDLTYELTVKSSEQTG 75
Query: 63 ---AASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERRFLEELR 119
+ S EL+ +C LE+QL+ + NAEL +E+ Q+ A+++ L +++ E+++LEEL+
Sbjct: 76 DGTSKSSELKKRCEELEAQLKVKENENAELLKELEQKNAMITVLENTIKEREKKYLEELK 135
Query: 120 RRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAPRPGPARAQPA 166
+SH+ T+L +EL++ AYL+ QLHAA+++L + G + A P+
Sbjct: 136 AKSHKLTLLSSELEQRASTIAYLTSQLHAAKKKLMS-SSGTSDASPS 181
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 57.0 bits (136), Expect = 2e-08
Identities = 69/261 (26%), Positives = 102/261 (39%), Gaps = 38/261 (14%)
Query: 17 VAMDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS--EAASRELESKCRA 74
V + ++Q ++R + L E L R E+ LQ R + E A +E +
Sbjct: 1271 VERSRLEARRELQELRRQMKMLDSENTRLGR----ELAELQGRLALGERAEKESRRETLG 1326
Query: 75 LESQLEARAAANAELRREVAQREALVSALRCSLRTEERRFLEEL-------RRRSHRATV 127
L +L A+ +R+E+ + + RT ERR L L +++ A
Sbjct: 1327 LRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARG 1386
Query: 128 LGTELQKHTEAAAYLSCQLHAARQRLQAPRPGPARAQPAQRA-------------RGPGV 174
L +L+ AA L +L AA R Q AR + +RA RG G+
Sbjct: 1387 LELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGL 1446
Query: 175 GARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDV 234
G + R G PARDA P G G + PS+ + + P P P
Sbjct: 1447 GRAPSPAPRPVPGSPARDA---PAEGSGEGLNSPSTLECSPGSQPPSPGPATSP------ 1497
Query: 235 SKASSPLLAREFLRGAERGHL 255
+SP L E +RGA R L
Sbjct: 1498 ---ASPDLDPEAVRGALREFL 1515
Score = 32.3 bits (72), Expect = 0.45
Identities = 48/179 (26%), Positives = 66/179 (36%), Gaps = 44/179 (24%)
Query: 49 LHLEILRLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALR---- 104
+ LE+ + R EA+ ++ SK AL L A +L R VAQ E SAL+
Sbjct: 718 VELELSMTKLRAEEASLQDSLSKLSALNESL---AQDKLDLNRLVAQLEEEKSALQGRQR 774
Query: 105 -----CSLRTEERRFLEELRRRSHRA----------------------TVLGTELQKHTE 137
++ EE+ LEELR A L E + E
Sbjct: 775 QAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQE 834
Query: 138 AAAYLSCQLHAARQRL-QAPRPGPARAQPAQRA---------RGPGVGARLAGVTRDGR 186
A LS QL Q L QA R + + +RA G+ +L R+GR
Sbjct: 835 QLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGR 893
Score = 32.0 bits (71), Expect = 0.59
Identities = 37/150 (24%), Positives = 61/150 (40%), Gaps = 15/150 (10%)
Query: 14 QAWVAMDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSEAASRELESKCR 73
Q ++D + ++ +R +EQ A H E L+ +R EAA RELE++
Sbjct: 959 QEKASLDKELMAQKLVQAEREAQASLREQRAA----HEEDLQRLQREKEAAWRELEAERA 1014
Query: 74 ALESQLEAR--------AAANAELRREVAQREALVSALRCSLRTEERRFLEELRRRSHRA 125
L+SQL+ A EL E+A AL L E + L +
Sbjct: 1015 QLQSQLQREQEELLARLEAEKEELSEEIA---ALQQERDEGLLLAESEKQQALSLKESEK 1071
Query: 126 TVLGTELQKHTEAAAYLSCQLHAARQRLQA 155
T L +L + A +S ++ ++ Q+
Sbjct: 1072 TALSEKLMGTRHSLATISLEMERQKRDAQS 1101
Score = 30.4 bits (67), Expect = 1.7
Identities = 54/215 (25%), Positives = 85/215 (39%), Gaps = 41/215 (19%)
Query: 25 EHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSEAASRELESKCRALESQL----- 79
E ++++ Q IS +K + L D L+ SE+ + +LE + R+LE +L
Sbjct: 1613 ESELRASQEKISKMKANETKLEGDKRR--LKEVLDASESRTVKLELQRRSLEGELQRSRL 1670
Query: 80 -----EARAAANAE----LRREVAQREALVSALRC-----------------SLRTEERR 113
EA+A A + L+R+VA E L+ +LR + R
Sbjct: 1671 GLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRG 1730
Query: 114 FLEELRRRS---HRATVLGTELQKHTEAAAY----LSCQLHAARQRL-QAPRPGPARAQP 165
E L + S + LQK A + L +L AARQ L +A + + +
Sbjct: 1731 LTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQ 1790
Query: 166 AQRARGPGVGARLAGVTRDGRGGPARDAARSPQAG 200
Q RG L V +G+ R+ R Q G
Sbjct: 1791 VQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEG 1825
Score = 30.0 bits (66), Expect = 2.2
Identities = 51/206 (24%), Positives = 80/206 (38%), Gaps = 28/206 (13%)
Query: 38 LKKEQMALLRDLHLEILRLQKRCSEAASRE---------LESKCRALESQLEARAAANA- 87
L ++ M L L ++++ +A SR+ L S+ R L +Q E AAA+A
Sbjct: 1074 LSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQ 1133
Query: 88 ELRREVAQREALVSALRCSLRTEER-----RFLEELR----------RRSHRATVLGTEL 132
E+RR Q L LR E R LE+ R +R R + G E+
Sbjct: 1134 EVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREV 1193
Query: 133 QKHTEAAAYLSCQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARD 192
Q+ EA A++R R ++A + +LA ++ + +
Sbjct: 1194 QRQ-EAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEE 1252
Query: 193 A--ARSPQAGPGSEGSRPSSRKRGEA 216
A A +AG G + R R EA
Sbjct: 1253 ARTAVGKEAGELRTGLQEVERSRLEA 1278
Score = 29.3 bits (64), Expect = 3.8
Identities = 35/147 (23%), Positives = 67/147 (45%), Gaps = 17/147 (11%)
Query: 5 GFARKPGGAQAWVAMDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSEAA 64
G R+ + + + S ++Q+ Q ++ Q L++ L +IL+ +KRCSE
Sbjct: 136 GLVRQSVELRRQLQEEQASYRRKLQAYQEG----QQRQAQLVQRLQGKILQYKKRCSELE 191
Query: 65 SRELESKCRALESQL----EARAAANAELR-REVAQREALVSALRCSLRTE-------ER 112
+ LE + +L ++ +A +R E QR A ++ + LR + +
Sbjct: 192 QQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQ 251
Query: 113 RFLEELRRRSHRATVLGTELQKHTEAA 139
E++R+ ++ T EL+ H EAA
Sbjct: 252 ALSEDIRKVTNDWTRCRKELE-HREAA 277
>gi|13994287 BTE-binding protein 4 [Homo sapiens]
Length = 252
Score = 49.3 bits (116), Expect = 4e-06
Identities = 35/97 (36%), Positives = 44/97 (45%), Gaps = 7/97 (7%)
Query: 146 LHAARQRLQAP-RPGPARAQPAQRARGPGVGAR----LAGVTRDGRGGPARDAARSPQAG 200
+ AAR+ +P PGP PA GPG A A + D RGGP + A
Sbjct: 43 VRAARREAASPGTPGPPPPPPAASGPGPGAAAAPHLLAASILADLRGGPGAAPGGASPAS 102
Query: 201 PGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKA 237
S S PSS + AAP+ +R PF PD +KA
Sbjct: 103 SSSAASSPSSGRAPGAAPSAAAKSHRCPF--PDCAKA 137
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 47.0 bits (110), Expect = 2e-05
Identities = 38/137 (27%), Positives = 62/137 (45%), Gaps = 7/137 (5%)
Query: 24 LEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQK---RCSEAASRELESK---CRALES 77
L H+++ + IS L K + AL + L E+ R + + A + L+S C L
Sbjct: 1291 LSHRVEEKESLISQLTKSKQALTQQLE-ELKRQMEEETKAKNAMAHALQSSRHDCDLLRE 1349
Query: 78 QLEARAAANAELRREVAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTE 137
Q E A AEL+R +++ + V+ R T+ + EEL + E +++TE
Sbjct: 1350 QYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTE 1409
Query: 138 AAAYLSCQLHAARQRLQ 154
A L +QRLQ
Sbjct: 1410 TANSKCASLEKTKQRLQ 1426
Score = 30.0 bits (66), Expect = 2.2
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 23/123 (18%)
Query: 19 MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSEAASRELESKCRALESQ 78
MD + + QI+ + F + A + D + L+ QK+ +EL+++ LE +
Sbjct: 1071 MDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKI-----KELQARIEELEEE 1125
Query: 79 LEARAAANAELRREVAQREALVSALRCSLRTEERRFLEELRRR---SHRATVLGTELQKH 135
+EA A++ ++ R++ R LEE+ R + AT E+ K
Sbjct: 1126 IEAEHTLRAKIEKQ---------------RSDLARELEEISERLEEASGATSAQIEMNKK 1170
Query: 136 TEA 138
EA
Sbjct: 1171 REA 1173
>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
Length = 508
Score = 43.1 bits (100), Expect = 3e-04
Identities = 54/226 (23%), Positives = 89/226 (39%), Gaps = 31/226 (13%)
Query: 22 VSLEHQIQSVQRHISFLKKEQM-------ALLRDLHLEILRLQKRCSEAAS--RELESKC 72
V LE +++++ + + EQ L +L + LRL ++ ++A+ +EL+ +
Sbjct: 119 VELEGDVEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQASQTEQELQREL 178
Query: 73 RALESQLEARAAANAELRREVAQREA---LVSALRCSLRTEERRFLEELRRRSHRATVLG 129
AL Q +A+A A AELR + + ++ + R L + R EE+ + R
Sbjct: 179 DALRGQCQAQALAGAELRTRLESLQGENQMLQSRRQDLEAQIRGLREEVEKGEGRLQTTH 238
Query: 130 TELQKHTEAAAYLSCQLHAAR-------------QRLQAPRPGPARAQPAQRARGPGVGA 176
EL S +L AR QR + +R Q A + +
Sbjct: 239 EELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESRLQDAD-VSAASLQS 297
Query: 177 RLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPK 222
LA DG G DA G P +RK P+PP+
Sbjct: 298 ELAHSLDDGDQGQGADA-----PGDTPTTRSPKTRKASSPQPSPPE 338
>gi|169163019 PREDICTED: hypothetical protein [Homo sapiens]
Length = 237
Score = 42.7 bits (99), Expect = 3e-04
Identities = 41/114 (35%), Positives = 53/114 (46%), Gaps = 13/114 (11%)
Query: 153 LQAPR-PGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSP---QAGPGSEGSRP 208
L+ PR P PA A PA RAR P + A R RG P R A +A G E S+P
Sbjct: 53 LRGPRAPSPAPALPA-RARPPRENRKRAVPARAARGPPKRPAGGQTGGVEAASGEERSQP 111
Query: 209 SSRKRGEAAPAPPK-SPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDS 261
+R AP P+ +P R+ + ++PLL RE +G G R DS
Sbjct: 112 RRPRRPPPAPRRPRPAPGRRKSLY-----EAAPLLTRE--KGGRSGRRGDRGDS 158
>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
Length = 855
Score = 42.7 bits (99), Expect = 3e-04
Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 37/203 (18%)
Query: 52 EILRLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEE 111
EIL + + A + EL + +AL S EAR A +AE E + EA AL TE+
Sbjct: 433 EILACKYHVAVAEAGELREQLKALRSTHEAREAQHAE---EKGRYEAEGQAL-----TEK 484
Query: 112 RRFLEELRRRSHRATV-LGTELQKHTEAAAYLSCQLHAARQRL---------------QA 155
LE+ R+ L EL+K ++ A L A+ L
Sbjct: 485 VSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMC 544
Query: 156 PRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSP----------QAGPGSEG 205
P R G G R + GR P RSP +AG G
Sbjct: 545 NNETPNRVMLDYYREGQGGAGR---TSPGGRTSPEARGRRSPILLPKGLLAPEAGRADGG 601
Query: 206 SRPSSRKRGEAAPAPPKSPNRQP 228
+ SS G + P+P P R+P
Sbjct: 602 TGDSSPSPGSSLPSPLSDPRREP 624
>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
Length = 824
Score = 42.7 bits (99), Expect = 3e-04
Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 37/203 (18%)
Query: 52 EILRLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEE 111
EIL + + A + EL + +AL S EAR A +AE E + EA AL TE+
Sbjct: 433 EILACKYHVAVAEAGELREQLKALRSTHEAREAQHAE---EKGRYEAEGQAL-----TEK 484
Query: 112 RRFLEELRRRSHRATV-LGTELQKHTEAAAYLSCQLHAARQRL---------------QA 155
LE+ R+ L EL+K ++ A L A+ L
Sbjct: 485 VSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMC 544
Query: 156 PRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSP----------QAGPGSEG 205
P R G G R + GR P RSP +AG G
Sbjct: 545 NNETPNRVMLDYYREGQGGAGR---TSPGGRTSPEARGRRSPILLPKGLLAPEAGRADGG 601
Query: 206 SRPSSRKRGEAAPAPPKSPNRQP 228
+ SS G + P+P P R+P
Sbjct: 602 TGDSSPSPGSSLPSPLSDPRREP 624
>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 42.4 bits (98), Expect = 4e-04
Identities = 69/225 (30%), Positives = 86/225 (38%), Gaps = 22/225 (9%)
Query: 50 HLEILRLQKR--CSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRC-- 105
H ILR R S L S+ + Q RA+ +R E R+ LV +
Sbjct: 358 HFHILRKVSRPDLSLLHGLGLRSRSESPAGQCVLRASQQRGVRLEGGGRQQLVPSQVAWR 417
Query: 106 SLRTEERRFLEELRRRSHRATV--------LGTELQKHTEAAAYLSCQLHAARQRLQAPR 157
+ R R LRRR R +G +Q A L +L + R R AP
Sbjct: 418 AARAPGRHQAAVLRRRRARVARAQQLARLRVGHAVQAPQALQAQLHARLPSRRARSSAPA 477
Query: 158 PGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAA 217
P A+ + AR P V AR A R R GPA AA G G P + E
Sbjct: 478 PS-AQGRCMTPARSP-VAAREAARLRGARPGPAASAATRMWQGSGRRRPGPDPQ---ELD 532
Query: 218 PAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAE----RGHLLYR 258
P S R P + P S+ S L E LRGA RG +L R
Sbjct: 533 PHCKLSFPRLP-LTPTESQPPSHNLFVEELRGARAALARGWMLPR 576
>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 42.4 bits (98), Expect = 4e-04
Identities = 69/225 (30%), Positives = 86/225 (38%), Gaps = 22/225 (9%)
Query: 50 HLEILRLQKR--CSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRC-- 105
H ILR R S L S+ + Q RA+ +R E R+ LV +
Sbjct: 358 HFHILRKVSRPDLSLLHGLGLRSRSESPAGQCVLRASQQRGVRLEGGGRQQLVPSQVAWR 417
Query: 106 SLRTEERRFLEELRRRSHRATV--------LGTELQKHTEAAAYLSCQLHAARQRLQAPR 157
+ R R LRRR R +G +Q A L +L + R R AP
Sbjct: 418 AARAPGRHQAAVLRRRRARVARAQQLARLRVGHAVQAPQALQAQLHARLPSRRARSSAPA 477
Query: 158 PGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAA 217
P A+ + AR P V AR A R R GPA AA G G P + E
Sbjct: 478 PS-AQGRCMTPARSP-VAAREAARLRGARPGPAASAATRMWQGSGRRRPGPDPQ---ELD 532
Query: 218 PAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAE----RGHLLYR 258
P S R P + P S+ S L E LRGA RG +L R
Sbjct: 533 PHCKLSFPRLP-LTPTESQPPSHNLFVEELRGARAALARGWMLPR 576
>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
sapiens]
Length = 384
Score = 42.0 bits (97), Expect = 6e-04
Identities = 47/158 (29%), Positives = 61/158 (38%), Gaps = 31/158 (19%)
Query: 142 LSCQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGP 201
L+C+ A R A RP P + G G GAR G G GGP AA SP A
Sbjct: 184 LTCRRCRAAPRRSA-RPFRRPGLPLKSRPGSGTGARSCGTWGSG-GGPGTAAASSPSADF 241
Query: 202 GSEGSRP-------------SSRKRGEA----------APAPPKSPNRQPFVLP---DVS 235
S+ +P R+R +PAPP+ R+P L VS
Sbjct: 242 SSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYRKPLTLSFGGGVS 301
Query: 236 KASSPLLA--REFLRGAERGHLLYREDSPSRSWPGPTC 271
+ P++A R F R R +R S + P P C
Sbjct: 302 SPTHPVVAPRRHFPRSVPRFPAGFRTHSLGTA-PKPKC 338
Score = 36.2 bits (82), Expect = 0.031
Identities = 39/109 (35%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 147 HAARQRLQAPRPGP------ARAQPAQRARGPGVGARLA-GVTRDGRGGPARDAARSPQA 199
H + RL+ PGP ARA PA A P AR A G G GP S Q
Sbjct: 113 HQSGSRLRPAAPGPRPGCSSARASPAPAA--PQAAARTAPGRAASGGSGPGSRGQGSDQV 170
Query: 200 G--PGSEGSRPS--SRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAR 244
G P G +P + +R AAP P R+P LP S+ S AR
Sbjct: 171 GARPSRAGGQPPPLTCRRCRAAPRRSARPFRRP-GLPLKSRPGSGTGAR 218
>gi|169163728 PREDICTED: hypothetical protein [Homo sapiens]
Length = 237
Score = 42.0 bits (97), Expect = 6e-04
Identities = 41/119 (34%), Positives = 53/119 (44%), Gaps = 16/119 (13%)
Query: 153 LQAPR-PGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSP---QAGPGSEGSRP 208
L+ PR P PA A PA RAR P + A R RG P R A +A G E S+P
Sbjct: 53 LRGPRAPSPAPALPA-RARPPRENRKRAVPARAARGPPKRPAGGQTGGVEAASGEERSQP 111
Query: 209 SSRKRGEAAPAPPK-SPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSW 266
+R AP P+ +P R+ + ++PLL RE +G G R D W
Sbjct: 112 RRPRRPPPAPRRPRPAPGRRKSLY-----EAAPLLTRE--KGGRSGR---RGDRGGSGW 160
>gi|169163708 PREDICTED: hypothetical protein [Homo sapiens]
Length = 237
Score = 42.0 bits (97), Expect = 6e-04
Identities = 41/119 (34%), Positives = 53/119 (44%), Gaps = 16/119 (13%)
Query: 153 LQAPR-PGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSP---QAGPGSEGSRP 208
L+ PR P PA A PA RAR P + A R RG P R A +A G E S+P
Sbjct: 53 LRGPRAPSPAPALPA-RARPPRENRKRAVPARAARGPPKRPAGGQTGGVEAASGEERSQP 111
Query: 209 SSRKRGEAAPAPPK-SPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSW 266
+R AP P+ +P R+ + ++PLL RE +G G R D W
Sbjct: 112 RRPRRPPPAPRRPRPAPGRRKSLY-----EAAPLLTRE--KGGRSGR---RGDRGGSGW 160
>gi|239744552 PREDICTED: hypothetical protein [Homo sapiens]
Length = 221
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 5/85 (5%)
Query: 145 QLHAARQRLQAPRPGPARAQPAQRARGPGV---GARLAGVTRDGRGGPARDAARSPQAGP 201
++ AA+ R A R G AR +PA+ ARGP GAR A + GP A R P +
Sbjct: 51 RVRAAQAR--ARRGGGARERPAEGARGPRAARGGARAAPMPSSAPRGPTEPALRRPSSAE 108
Query: 202 GSEGSRPSSRKRGEAAPAPPKSPNR 226
PSS AP SP+R
Sbjct: 109 RPLAQAPSSSASVGRAPGAMASPSR 133
Score = 32.0 bits (71), Expect = 0.59
Identities = 30/77 (38%), Positives = 32/77 (41%), Gaps = 9/77 (11%)
Query: 170 RGPGVGARLAGVTRDGRGGPAR----DAARSPQAGPGS--EGSRPSSRKRGEAAPA--PP 221
R PG G A R RGG AR + AR P+A G PSS RG PA P
Sbjct: 45 RPPGPGRVRAAQARARRGGGARERPAEGARGPRAARGGARAAPMPSSAPRGPTEPALRRP 104
Query: 222 KSPNRQPFVLPDVSKAS 238
S R P S AS
Sbjct: 105 SSAER-PLAQAPSSSAS 120
>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
sapiens]
Length = 384
Score = 42.0 bits (97), Expect = 6e-04
Identities = 47/158 (29%), Positives = 61/158 (38%), Gaps = 31/158 (19%)
Query: 142 LSCQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGP 201
L+C+ A R A RP P + G G GAR G G GGP AA SP A
Sbjct: 184 LTCRRCRAAPRRSA-RPFRRPGLPLKSRPGSGTGARSCGTWGSG-GGPGTAAASSPSADF 241
Query: 202 GSEGSRP-------------SSRKRGEA----------APAPPKSPNRQPFVLP---DVS 235
S+ +P R+R +PAPP+ R+P L VS
Sbjct: 242 SSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYRKPLTLSFGGGVS 301
Query: 236 KASSPLLA--REFLRGAERGHLLYREDSPSRSWPGPTC 271
+ P++A R F R R +R S + P P C
Sbjct: 302 SPTHPVVAPRRHFPRSVPRFPAGFRTHSLGTA-PKPKC 338
Score = 36.2 bits (82), Expect = 0.031
Identities = 39/109 (35%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 147 HAARQRLQAPRPGP------ARAQPAQRARGPGVGARLA-GVTRDGRGGPARDAARSPQA 199
H + RL+ PGP ARA PA A P AR A G G GP S Q
Sbjct: 113 HQSGSRLRPAAPGPRPGCSSARASPAPAA--PQAAARTAPGRAASGGSGPGSRGQGSDQV 170
Query: 200 G--PGSEGSRPS--SRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAR 244
G P G +P + +R AAP P R+P LP S+ S AR
Sbjct: 171 GARPSRAGGQPPPLTCRRCRAAPRRSARPFRRP-GLPLKSRPGSGTGAR 218
>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
Length = 384
Score = 42.0 bits (97), Expect = 6e-04
Identities = 47/158 (29%), Positives = 61/158 (38%), Gaps = 31/158 (19%)
Query: 142 LSCQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGP 201
L+C+ A R A RP P + G G GAR G G GGP AA SP A
Sbjct: 184 LTCRRCRAAPRRSA-RPFRRPGLPLKSRPGSGTGARSCGTWGSG-GGPGTAAASSPSADF 241
Query: 202 GSEGSRP-------------SSRKRGEA----------APAPPKSPNRQPFVLP---DVS 235
S+ +P R+R +PAPP+ R+P L VS
Sbjct: 242 SSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYRKPLTLSFGGGVS 301
Query: 236 KASSPLLA--REFLRGAERGHLLYREDSPSRSWPGPTC 271
+ P++A R F R R +R S + P P C
Sbjct: 302 SPTHPVVAPRRHFPRSVPRFPAGFRTHSLGTA-PKPKC 338
Score = 36.2 bits (82), Expect = 0.031
Identities = 39/109 (35%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 147 HAARQRLQAPRPGP------ARAQPAQRARGPGVGARLA-GVTRDGRGGPARDAARSPQA 199
H + RL+ PGP ARA PA A P AR A G G GP S Q
Sbjct: 113 HQSGSRLRPAAPGPRPGCSSARASPAPAA--PQAAARTAPGRAASGGSGPGSRGQGSDQV 170
Query: 200 G--PGSEGSRPS--SRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAR 244
G P G +P + +R AAP P R+P LP S+ S AR
Sbjct: 171 GARPSRAGGQPPPLTCRRCRAAPRRSARPFRRP-GLPLKSRPGSGTGAR 218
>gi|61966741 TMF regulated nuclear protein [Homo sapiens]
Length = 227
Score = 42.0 bits (97), Expect = 6e-04
Identities = 46/129 (35%), Positives = 55/129 (42%), Gaps = 10/129 (7%)
Query: 82 RAAANAELRR---EVAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEA 138
RA AE RR EV R LVS L + R FL R +HRA L +A
Sbjct: 99 RALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQA 158
Query: 139 AAYLSCQLHAARQRLQAPRPGPARAQPAQRARGPGVGARL---AGVTRDGRG-GPARDAA 194
YL+ H +R + + PR G PA A G+G + AG R G G P
Sbjct: 159 ELYLAA--HGSRLK-KGPRRGRRGRPPALLASALGLGGCVPWGAGRLRRGHGPEPDSPFR 215
Query: 195 RSPQAGPGS 203
RSP GP S
Sbjct: 216 RSPPRGPAS 224
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 41.6 bits (96), Expect = 7e-04
Identities = 56/208 (26%), Positives = 78/208 (37%), Gaps = 39/208 (18%)
Query: 10 PGGAQAWVAMDTVSLEHQIQSVQRHISFLKKEQMALLRDL---HLEILRLQKRCSEA--- 63
PG + A + +L ++ ++R L E A R L + E RL K ++A
Sbjct: 716 PGESLASGVAEQEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQARRA 775
Query: 64 ---ASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCS-------------- 106
A RE E++ EA AA EL +REALV AL +
Sbjct: 776 EAEAHREAEAQAWEQARLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRL 835
Query: 107 -------------LRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQL-HAARQR 152
L +E R+ LEE R L EL+K L +L H R+
Sbjct: 836 RAQSEAAEERMQVLESEGRQHLEEAERERREKEALQAELEKAVVRGKELGARLEHLQREL 895
Query: 153 LQA--PRPGPARAQPAQRARGPGVGARL 178
QA R R + +Q R G+ RL
Sbjct: 896 EQAALERQEFLREKESQHQRYQGLEQRL 923
Score = 32.3 bits (72), Expect = 0.45
Identities = 45/173 (26%), Positives = 61/173 (35%), Gaps = 9/173 (5%)
Query: 25 EHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSEAASRELESKCRALESQLEARAA 84
E Q S Q + L +E+ LR+ + RLQ+ RE A +SQLE
Sbjct: 301 EAQALSGQAKRAELYREEAEALRERAGRLPRLQEELRRC--RERLQAAEAYKSQLEEERV 358
Query: 85 ANAELRREVAQREALVSALR--CSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYL 142
+ L A E + A R C+ E +R LR R A L+ + A
Sbjct: 359 LSGVLEASKALLEEQLEAARERCARLHETQRENLLLRTRLGEAHAELDSLRHQVDQLAEE 418
Query: 143 SCQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAAR 195
+ +L QR P PG P G L R+ G R R
Sbjct: 419 NVELELELQRSLEPPPGSPGEAPL-----AGAAPSLQDEVREAEAGRLRTLER 466
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/71 (38%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 160 PARAQPAQRARGPGVGARLAGVTRDGRGGP-ARDAARSPQAGPGS-EGSRPSSRKRGEAA 217
P RA+PA + PG R RGGP + ++RSP P S SR S+ R +A
Sbjct: 462 PPRARPASTSPSPGAHGR--------RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSA 513
Query: 218 PAPPKSPNRQP 228
P SP+R P
Sbjct: 514 EKRPHSPSRSP 524
Score = 39.7 bits (91), Expect = 0.003
Identities = 44/194 (22%), Positives = 79/194 (40%), Gaps = 33/194 (17%)
Query: 55 RLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERRF 114
RL+ CS +S L K ++++ R+ + + +R R + + + ++R
Sbjct: 186 RLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKN-KEKKRPH 244
Query: 115 LEELRRRSHRATVLGTELQKHTEAAAYL-SCQLHAARQRLQAPRPGPARAQPAQRARGPG 173
E RRSHR H+ +++ S H + R P+R P R G
Sbjct: 245 TESPGRRSHR----------HSSGSSHSPSLSSHYSDSR------SPSRLSPKHRDEGRK 288
Query: 174 VGARLAGVTRD-------GRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNR 226
G++ + +R G G P R+ ++G + G RP S A +PP P+
Sbjct: 289 TGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSG--AHGGRPGS------AHSPPDKPSS 340
Query: 227 QPFVLPDVSKASSP 240
+ D + A++P
Sbjct: 341 PSPRVRDKAAAAAP 354
Score = 31.6 bits (70), Expect = 0.77
Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 6/76 (7%)
Query: 157 RPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAA------RSPQAGPGSEGSRPSS 210
R A A P ARG + + + GRGG A A R + S S P
Sbjct: 346 RDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRR 405
Query: 211 RKRGEAAPAPPKSPNR 226
R R PAPP+ +R
Sbjct: 406 RGRRRPRPAPPRGSSR 421
Score = 29.3 bits (64), Expect = 3.8
Identities = 18/75 (24%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
Query: 38 LKKEQMALLRDLHLEILRLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQRE 97
L+ + L++ H EIL +++ R +E KC L+ +E + + E+R++V
Sbjct: 39 LRAAEPGLVKRAHREILDHERK------RRVELKCMELQEMMEEQGYSEEEIRQKVGTFR 92
Query: 98 ALVSALRCSLRTEER 112
++ L E+R
Sbjct: 93 QMLMEKEGVLTREDR 107
Score = 28.9 bits (63), Expect = 5.0
Identities = 39/139 (28%), Positives = 44/139 (31%), Gaps = 31/139 (22%)
Query: 155 APRPGPARAQPAQRARGPGVGARLAGVTRDGRG-----GPARDAARSPQAGPGSEGSRPS 209
+PR P+ RA G G G R R R P R R P+ P SR
Sbjct: 365 SPRSAPSSQGRGGRAAG-GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSL 423
Query: 210 SRKR-------GEAAPAPPKSP--------------NRQPFVLPDVSKASSPLLAREFLR 248
SR R G AP P P R P P ++SP R
Sbjct: 424 SRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP---ASTSPSPGAHGRR 480
Query: 249 GAERGHLLYREDSP-SRSW 266
G G R P RSW
Sbjct: 481 GGPEGKSSSRSPGPHPRSW 499
>gi|49472835 bridging integrator 2 [Homo sapiens]
Length = 565
Score = 41.2 bits (95), Expect = 0.001
Identities = 51/180 (28%), Positives = 72/180 (40%), Gaps = 18/180 (10%)
Query: 51 LEILRLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE 110
LE ++K SEA+S E + A +A+ + E R +Q E L S S
Sbjct: 316 LEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTE--RAKSQEEVLPS----STTPS 369
Query: 111 ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAP--RPGPARAQPAQR 168
L + S AT + L+ T + + A+ QR AP RP P RA + R
Sbjct: 370 PGGALSPSGQPSSSATEV--VLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPR 427
Query: 169 ARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQP 228
P G + T G G P SP+A G+ + P + P PP+ P R P
Sbjct: 428 ---PSSGNIPSSPTASGGGSPT-----SPRASLGTGTASPRTSLEVSPNPEPPEKPVRTP 479
>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
Length = 564
Score = 40.8 bits (94), Expect = 0.001
Identities = 59/226 (26%), Positives = 80/226 (35%), Gaps = 24/226 (10%)
Query: 61 SEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERRFLEELRR 120
S+AA R + + AAA L + L A+R L T E E+ R
Sbjct: 297 SKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEE---EDPRS 353
Query: 121 RSHRATVLGTELQKHTEAAAYLS-CQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLA 179
G+EL E S + R + +P P + P R RG G G+ L
Sbjct: 354 GRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLT 413
Query: 180 GVTRDGRGGPARDAARSPQAGP--GSEGSRPSSRKRGE------AAPAPPKSPNRQPFVL 231
+ GRG + + GS RP RG ++PA P+SP R P V
Sbjct: 414 QLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPA-PQSPPRSPSV- 471
Query: 232 PDVSKASSPLLAREFL------RGAERGHLLYREDSPSRSWPGPTC 271
+A P L L R A + SP+ W G C
Sbjct: 472 ----RAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRC 513
Score = 30.0 bits (66), Expect = 2.2
Identities = 36/130 (27%), Positives = 42/130 (32%), Gaps = 13/130 (10%)
Query: 148 AARQRLQAPRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSR 207
AA R Q R RA P V A G G GG R +P + S G
Sbjct: 225 AAGARAQV-RGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRP 283
Query: 208 PSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAR------------EFLRGAERGHL 255
R E P K+ V+ AS P LA L+GA R L
Sbjct: 284 TGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDL 343
Query: 256 LYREDSPSRS 265
E+ RS
Sbjct: 344 STAEEEDPRS 353
>gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
Length = 564
Score = 40.8 bits (94), Expect = 0.001
Identities = 59/226 (26%), Positives = 80/226 (35%), Gaps = 24/226 (10%)
Query: 61 SEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERRFLEELRR 120
S+AA R + + AAA L + L A+R L T E E+ R
Sbjct: 297 SKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEE---EDPRS 353
Query: 121 RSHRATVLGTELQKHTEAAAYLS-CQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLA 179
G+EL E S + R + +P P + P R RG G G+ L
Sbjct: 354 GRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGGSGLT 413
Query: 180 GVTRDGRGGPARDAARSPQAGP--GSEGSRPSSRKRGE------AAPAPPKSPNRQPFVL 231
+ GRG + + GS RP RG ++PA P+SP R P V
Sbjct: 414 QLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLSSPA-PQSPPRSPSV- 471
Query: 232 PDVSKASSPLLAREFL------RGAERGHLLYREDSPSRSWPGPTC 271
+A P L L R A + SP+ W G C
Sbjct: 472 ----RAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRC 513
Score = 30.0 bits (66), Expect = 2.2
Identities = 36/130 (27%), Positives = 42/130 (32%), Gaps = 13/130 (10%)
Query: 148 AARQRLQAPRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSR 207
AA R Q R RA P V A G G GG R +P + S G
Sbjct: 225 AAGARAQV-RGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRP 283
Query: 208 PSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAR------------EFLRGAERGHL 255
R E P K+ V+ AS P LA L+GA R L
Sbjct: 284 TGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDL 343
Query: 256 LYREDSPSRS 265
E+ RS
Sbjct: 344 STAEEEDPRS 353
>gi|210031154 zinc finger protein 541 [Homo sapiens]
Length = 1365
Score = 40.8 bits (94), Expect = 0.001
Identities = 45/149 (30%), Positives = 61/149 (40%), Gaps = 18/149 (12%)
Query: 135 HTEAAAYLSCQLHAARQRLQAPRP--GPARAQPAQRARGPGVGARLAGVTR-DGRGGPAR 191
H + AA +S QL A + A RP GP QP A P V + AG + G PAR
Sbjct: 570 HAQVAA-VSSQLPAPEGKPAALRPLQGPWPQQPPPLA--PAVDSLHAGPGNPEAEGSPAR 626
Query: 192 DAARSP----QAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLARE-- 245
+P +A PGS + A P P +P+ P PD+S + L + +
Sbjct: 627 RRKTTPGVPREASPGSTRRDAKGGLKVAAVPTPLAAPSLDPSRNPDISSLAKQLRSSKGT 686
Query: 246 ------FLRGAERGHLLYREDSPSRSWPG 268
F +R L E+ P S PG
Sbjct: 687 LDLEDIFPSTGQRQTQLGGEEPPGASLPG 715
>gi|222446647 coiled-coil domain containing 153 [Homo sapiens]
Length = 210
Score = 40.4 bits (93), Expect = 0.002
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 5/147 (3%)
Query: 24 LEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSEAASRELESKCRALESQLEA-- 81
L ++Q V+ + + E A+ ++ + LQ+ + S++LE + + L QLEA
Sbjct: 62 LRQRLQGVEAELEGARSEGKAIYAEMSRQCHALQEDM-QTRSKQLEEEVKGLRGQLEACQ 120
Query: 82 --RAAANAELRREVAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAA 139
AAA E + + +R+ ++ LR + E ++ E L R +++ + A
Sbjct: 121 REAAAAREEAEQALGERDQALAQLRAHMADMEAKYEEILHDSLDRLLAKLRAIKQQWDGA 180
Query: 140 AYLSCQLHAARQRLQAPRPGPARAQPA 166
A H +QR P + PA
Sbjct: 181 ALRLHARHKEQQRQFGLTPPGSLRPPA 207
Score = 31.2 bits (69), Expect = 1.0
Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 38 LKKEQMALLRDLHLEILRLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQRE 97
L+KE LLRD HL + R + R ++A+ +L + + +E++LE A +E + A+
Sbjct: 36 LEKE---LLRD-HLALRRDEARRAKASEDQLRQRLQGVEAELE---GARSEGKAIYAEMS 88
Query: 98 ALVSALRCSLRTEERRFLEELR 119
AL+ ++T ++ EE++
Sbjct: 89 RQCHALQEDMQTRSKQLEEEVK 110
>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
Length = 696
Score = 40.4 bits (93), Expect = 0.002
Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 18/186 (9%)
Query: 57 QKRCSEAASRELESKCRALESQLEARAAANAE--LRREVAQREALVSALRCSLRTEERRF 114
+++ AASR +K +A E+ +A AAN E + R +A RE + ++RR
Sbjct: 381 RQKAEIAASRTSHAKAKA-EAAEQAALAANQESNIARTLA-RELAPDFYQPGPEYQKRRL 438
Query: 115 LEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAPRPGPARAQPAQRARGPGV 174
L+E+ S E AA L + Q + P P P+ P
Sbjct: 439 LQEILENSESLL----EPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQP 494
Query: 175 GARLAGVTRDG-------RGGPARDAARS--PQAGPGSEG-SRPSSRKRGEAAPAPPKSP 224
GV++DG G P+ + +RS P G G +RP++ + A P +P
Sbjct: 495 KRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEGAGRRSPARPATERMAIEALQAPPAP 554
Query: 225 NRQPFV 230
+R+P V
Sbjct: 555 SREPEV 560
>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
Length = 474
Score = 40.0 bits (92), Expect = 0.002
Identities = 52/218 (23%), Positives = 84/218 (38%), Gaps = 29/218 (13%)
Query: 29 QSVQRHISFLKKEQMALLRDLHLEILRLQKRCSEAASRELESKCRALESQLEARAAANAE 88
+++ RHI FLK E L + L Q + SE ++ LE + E L + +
Sbjct: 256 ENMMRHIRFLKNEVERLKKQLR----AAQLQHSEKMAQYLEEERHMREENLRLQ----RK 307
Query: 89 LRREVAQREAL---VSALRCSLRTEERRFLEELRRRSHRATVLGTEL--QKHTEAAAYLS 143
L+RE+ +REAL +S SL ++ R+ E+ + R + + + ++ +S
Sbjct: 308 LQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPIS 367
Query: 144 CQLHAARQRLQAPRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGS 203
L A + P PG+ + G + G R + R
Sbjct: 368 PGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSH----GITRPSPR-------- 415
Query: 204 EGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPL 241
+ P KR P PP SPN Q V P P+
Sbjct: 416 RSNSPDKFKR----PTPPPSPNTQTPVQPPPPPPPPPM 449
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 7/90 (7%)
Query: 155 APRPGPARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRG 214
AP+ P+ A + R P G R RG P + RS + PGS G+ P SR R
Sbjct: 495 APKTPPSSATKQVQRRPPPAGPR------SERGEPPKSGDRSGYSSPGSPGT-PGSRSRT 547
Query: 215 EAAPAPPKSPNRQPFVLPDVSKASSPLLAR 244
+ P PP ++ V+ K+ S +R
Sbjct: 548 PSLPTPPTREPKKVAVVRTPPKSPSSAKSR 577
Score = 32.3 bits (72), Expect = 0.45
Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 17/98 (17%)
Query: 154 QAPRPGPARAQPAQRARG------PGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSR 207
+A P P+ QPA RG P + AR+ ++DG G + A S ++ + +R
Sbjct: 348 EADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNR 407
Query: 208 PSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLARE 245
P +P P + P + P SSP + E
Sbjct: 408 PC------LSPKHPTPGSSDPLIQP-----SSPAVCPE 434
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.130 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,176,228
Number of Sequences: 37866
Number of extensions: 661688
Number of successful extensions: 8489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 891
Number of HSP's that attempted gapping in prelim test: 6507
Number of HSP's gapped (non-prelim): 2726
length of query: 272
length of database: 18,247,518
effective HSP length: 101
effective length of query: 171
effective length of database: 14,423,052
effective search space: 2466341892
effective search space used: 2466341892
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.