Search of human proteins with 119220562

Search of human proteins with 119220562

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119220562 cytochrome P450, family 4, subfamily F,
polypeptide 3 [Homo sapiens]
         (520 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide...  1084   0.0  
gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide ...   942   0.0  
gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11...   902   0.0  
gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11...   902   0.0  
gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide...   847   0.0  
gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8...   832   0.0  
gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide...   696   0.0  
gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide...   424   e-118
gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide...   409   e-114
gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide...   405   e-113
gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide ...   403   e-112
gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide ...   397   e-110
gi|30023836 cytochrome P450 4Z1 [Homo sapiens]                        370   e-102
gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide...   275   7e-74
gi|239757171 PREDICTED: similar to cytochrome P450, family 4, su...   263   3e-70
gi|239751683 PREDICTED: similar to cytochrome P450, family 4, su...   263   3e-70
gi|239746187 PREDICTED: similar to cytochrome P450, family 4, su...   263   3e-70
gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7...   155   8e-38
gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide ...   155   1e-37
gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide ...   150   2e-36
gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide ...   147   2e-35
gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5...   142   6e-34
gi|5729796 cytochrome P450, family 46 [Homo sapiens]                  141   1e-33
gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide ...   118   1e-26
gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [H...   115   1e-25
gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [H...   115   1e-25
gi|4503211 cytochrome P450, family 27, subfamily A, polypeptide ...   107   3e-23
gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide ...   103   4e-22
gi|16933528 cytochrome P450, family 26, subfamily A, polypeptide...   102   1e-21
gi|16933530 cytochrome P450, family 26, subfamily A, polypeptide...   102   1e-21

>gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide 3
           [Homo sapiens]
          Length = 520

 Score = 1084 bits (2803), Expect = 0.0
 Identities = 520/520 (100%), Positives = 520/520 (100%)

Query: 1   MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF 60
           MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF
Sbjct: 1   MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF 60

Query: 61  LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK 120
           LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK
Sbjct: 61  LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK 120

Query: 121 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL
Sbjct: 121 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL 240
           LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL
Sbjct: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL 240

Query: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
           LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID
Sbjct: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE
Sbjct: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420
           LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC
Sbjct: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
Sbjct: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520
           VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
Sbjct: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520


>gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide 2
           [Homo sapiens]
          Length = 520

 Score =  942 bits (2435), Expect = 0.0
 Identities = 456/520 (87%), Positives = 479/520 (92%)

Query: 1   MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF 60
           M QLSLS LGLWP+AASPWLLLLLVGASWLLA +LAWTY FYDNC RLRCFPQPP+RNWF
Sbjct: 1   MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF 60

Query: 61  LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK 120
            GH G+++ +EEG+     L  T+      W+GP   ++ + HP  I+ V+ A AAI PK
Sbjct: 61  WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK 120

Query: 121 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           DK FYSFL+PWLGDGLLLSAG+KWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL
Sbjct: 121 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL 240
           LASEGSA LDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALV+KRH +IL
Sbjct: 181 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL 240

Query: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
           L+IDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID
Sbjct: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE
Sbjct: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420
           LLKDREPKEIEWDDLA LPFLTMC+KESLRLHPPVP +SR  TQDIVLPDGRVIPKGIIC
Sbjct: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LISVFGTHHNPAVWPDPEVYDPFRFDP+NIKERSPLAFIPFSAGPRNCIGQ FAMAEMKV
Sbjct: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480

Query: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520
           VL LTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
Sbjct: 481 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520


>gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score =  902 bits (2331), Expect = 0.0
 Identities = 431/519 (83%), Positives = 466/519 (89%)

Query: 1   MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF 60
           MPQLSLS LGL P+AASPWLLLLLVG SWLLAR+LAWTYTFYDNC RL+CFPQPPK+NWF
Sbjct: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60

Query: 61  LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK 120
            GH GL+  +EEG+     L  T+      W+GP   ++ + HP  I+P+  A AA+ PK
Sbjct: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120

Query: 121 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           D +FY FLKPWLGDGLLLS G+KWSRHRRMLTPAFHFNILKPYMKIFN+SVNIMH KWQ 
Sbjct: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL 240
           LASEGSARLDMFEHISLMTLDSLQKCVFSF+S+CQEKPSEYIAAILELSA V KR+QQIL
Sbjct: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240

Query: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
           L+ DFLYYLTPDGQRFRRAC LVHDFTDAVIQERR TLP+QG+DDFL+ KAKSKTLDFID
Sbjct: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGK+LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQE+CRQEVQE
Sbjct: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420
           LLKDREP EIEWDDLAQLPFLTMCIKESLRLHPPVP +SRCCTQD VLPDGRVIPKGI+C
Sbjct: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LI++ G H+NP VWPDPEVYDPFRFD +NIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
Sbjct: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519
           VL LTLL FR+LP HTEPRRKPEL+LRAEGGLWLRVEPL
Sbjct: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPL 519


>gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score =  902 bits (2331), Expect = 0.0
 Identities = 431/519 (83%), Positives = 466/519 (89%)

Query: 1   MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF 60
           MPQLSLS LGL P+AASPWLLLLLVG SWLLAR+LAWTYTFYDNC RL+CFPQPPK+NWF
Sbjct: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60

Query: 61  LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK 120
            GH GL+  +EEG+     L  T+      W+GP   ++ + HP  I+P+  A AA+ PK
Sbjct: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120

Query: 121 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           D +FY FLKPWLGDGLLLS G+KWSRHRRMLTPAFHFNILKPYMKIFN+SVNIMH KWQ 
Sbjct: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL 240
           LASEGSARLDMFEHISLMTLDSLQKCVFSF+S+CQEKPSEYIAAILELSA V KR+QQIL
Sbjct: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240

Query: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
           L+ DFLYYLTPDGQRFRRAC LVHDFTDAVIQERR TLP+QG+DDFL+ KAKSKTLDFID
Sbjct: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGK+LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQE+CRQEVQE
Sbjct: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420
           LLKDREP EIEWDDLAQLPFLTMCIKESLRLHPPVP +SRCCTQD VLPDGRVIPKGI+C
Sbjct: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LI++ G H+NP VWPDPEVYDPFRFD +NIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
Sbjct: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519
           VL LTLL FR+LP HTEPRRKPEL+LRAEGGLWLRVEPL
Sbjct: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPL 519


>gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide 12
           [Homo sapiens]
          Length = 524

 Score =  847 bits (2188), Expect = 0.0
 Identities = 408/520 (78%), Positives = 448/520 (86%)

Query: 1   MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF 60
           M  LSL  LGL P+A SPWLLLLLV  SWLLARILAWTY FY+NC RL+CFPQPPKRNWF
Sbjct: 1   MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF 60

Query: 61  LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK 120
            GHLGLI  +EEGL  +  ++ T+      W+GP    + + HP  I+ +  A AAI PK
Sbjct: 61  WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK 120

Query: 121 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           D +F  FLKPWLG+G+LLS G+KWSRHRRMLTPAFHFNILK Y+ IFN+S NIM  KWQ 
Sbjct: 121 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL 240
           LASEGS+RLDMFEHISLMTLDSLQKC+FSFDSHCQE+PSEYIA ILELSALV KR Q IL
Sbjct: 181 LASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL 240

Query: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
            ++DFLYYL+ DG+RF RACRLVHDFTDAVI+ERRRTLP+QG+DDF + KAKSKTLDFID
Sbjct: 241 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLSKDEDGK LSDEDIRAEADTFMF GHDTTASGLSWVLY+LA+HPEYQERCRQEVQE
Sbjct: 301 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420
           LLKDR+PKEIEWDDLAQLPFLTMC+KESLRLHPP P +SRCCTQDIVLPDGRVIPKGI C
Sbjct: 361 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LI + G HHNP VWPDPEVYDPFRFDP+N K RSPLAFIPFSAGPRNCIGQAFAMAEMKV
Sbjct: 421 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS 520
           VL L LL FR LPDHTEPRRK EL++RAEGGLWLRVEPL+
Sbjct: 481 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLN 520


>gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8
           [Homo sapiens]
          Length = 520

 Score =  832 bits (2150), Expect = 0.0
 Identities = 401/519 (77%), Positives = 445/519 (85%)

Query: 1   MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF 60
           M  LSLS LGL P+AASPWLLLL+VGASWLLARILAWTY FY N  RLRCFPQP K+NWF
Sbjct: 1   MSLLSLSWLGLRPVAASPWLLLLVVGASWLLARILAWTYAFYHNGRRLRCFPQPRKQNWF 60

Query: 61  LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK 120
           LGHLGL+  +EEGL     L  T+      W+GP   I+ + HP  ++ V+    AI  K
Sbjct: 61  LGHLGLVTPTEEGLRVLTQLVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDK 120

Query: 121 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180
           D VFY  LKPWLGDGLLLS G+KW  HRR+LTPAFHFNILKPY+KIF++S NIMHAKWQ 
Sbjct: 121 DIVFYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQR 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL 240
           LA EGS  LD+FEHISLMTLDSLQKC+FSFDS+CQEKPSEYI AI+ELSALV KR+ Q  
Sbjct: 181 LAMEGSTCLDVFEHISLMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFF 240

Query: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
            Y DFLY+LTP G+RF RACRLVHDFTDAVIQERRRTL SQGVDDFLQAKAKSKTLDFID
Sbjct: 241 RYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           VLLLS+D++GK+LSDEDIRAEADTFMF GHDTTASGLSWVLY+LA+HPEYQERCRQEVQE
Sbjct: 301 VLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE 360

Query: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420
           LLKDREPKEIEWDDLAQLPFLTMC+KESLRLHPP+P  +R CTQD+VLPD RVIPKG +C
Sbjct: 361 LLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVC 420

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
            I++F  HHNP+VWPDPEVYDPFRFDP+N ++RSP+AFIPFSAGPRNCIGQ FAMAEMKV
Sbjct: 421 NINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKV 480

Query: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519
           VL LTLLRFR+LPDH EPRR PE+VLRAE GLWLRVEPL
Sbjct: 481 VLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLRVEPL 519


>gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide 22
           [Homo sapiens]
          Length = 531

 Score =  696 bits (1795), Expect = 0.0
 Identities = 334/506 (66%), Positives = 410/506 (81%), Gaps = 2/506 (0%)

Query: 15  AASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGL 74
           A S  LL LL     LL R L    +FY  C RLRCFPQPP+RNW LGHLG+   +E GL
Sbjct: 23  AVSTLLLFLLFFLFRLLLRFLRLCRSFYITCRRLRCFPQPPRRNWLLGHLGMYLPNEAGL 82

Query: 75  LYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGD 134
              + +      +   W+GP   ++ + HP YIKP+L A AAI PKD +FY FLKPWLGD
Sbjct: 83  QDEKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGD 142

Query: 135 GLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEH 194
           GLLLS G+KWSRHRR+LTPAFHF+ILKPYMKIFN+S +IMHAKW+ LA   +  LDMFEH
Sbjct: 143 GLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEH 202

Query: 195 ISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQ 254
           ISLMTLDSLQKCVFS++S+CQEK S+YI+AI+ELSAL  +R  ++  Y+DF+YY + DG+
Sbjct: 203 ISLMTLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHYLDFIYYRSADGR 262

Query: 255 RFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLS 314
           RFR+AC +VH FT  VIQERRR L  QG + +L+AK + KTLDFIDVLLL++DEDGK+LS
Sbjct: 263 RFRQACDMVHHFTTEVIQERRRALRQQGAEAWLKAK-QGKTLDFIDVLLLARDEDGKELS 321

Query: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
           DEDIRAEADTFMFEGHDTT+SG+SW+L++LAK+PEYQE+CR+E+QE++K RE +E+EWDD
Sbjct: 322 DEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDD 381

Query: 375 LAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW 434
           L QLPF TMCIKESLR +PPV  VSR CT+DI LPDGR+IPKGIICL+S++GTHHNP VW
Sbjct: 382 LTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVW 441

Query: 435 PDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPD 494
           PD +VY+P+RFDP N ++RSPLA++PFSAGPRNCIGQ+FAMAE++VV+ LTLLRFR+  D
Sbjct: 442 PDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVD 501

Query: 495 HT-EPRRKPELVLRAEGGLWLRVEPL 519
            T + RRKPEL+LR E GLWL+VEPL
Sbjct: 502 RTRKVRRKPELILRTENGLWLKVEPL 527


>gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide 11
           [Homo sapiens]
          Length = 519

 Score =  424 bits (1090), Expect = e-118
 Identities = 235/508 (46%), Positives = 315/508 (62%), Gaps = 22/508 (4%)

Query: 15  AASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGL 74
           AAS  +LLLL+  +  L     W          L+ FP PP  +W  GH+  +   +E L
Sbjct: 21  AASLLILLLLLIKAVQLYLHRQWLLK------ALQQFPCPPS-HWLFGHIQELQQDQE-L 72

Query: 75  LYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGD 134
              Q    TF   C  W+      V+++ P Y+K +L       PK    Y FL PW+G 
Sbjct: 73  QRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVIL---GRSDPKSHGSYRFLAPWIGY 129

Query: 135 GLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEH 194
           GLLL  G+ W +HRRMLTPAFH++ILKPY+ +  +SV +M  KW+ L  + S  L++F+H
Sbjct: 130 GLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSP-LEVFQH 188

Query: 195 ISLMTLDSLQKCVFSFDSHCQ--EKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPD 252
           +SLMTLD++ KC FS     Q       YI AI +L+ LV  R +      D +Y LT  
Sbjct: 189 VSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSA 248

Query: 253 GQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKK 312
           G+   RAC+L H  TD VIQ R+  L  +G    L+   + + LDF+D+LLL+K E+G  
Sbjct: 249 GRWTHRACQLAHQHTDQVIQLRKAQLQKEGE---LEKIKRKRHLDFLDILLLAKMENGSI 305

Query: 313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372
           LSD+D+RAE DTFMFEGHDTTASG+SW+LY LA HP++QERCR+E+  LL D     I W
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGA--SITW 363

Query: 373 DDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPA 432
           + L Q+P+ TMCIKE+LRL+PPVP + R  +  +  PDGR +PKGI+ L+S++G HHNP 
Sbjct: 364 NHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPK 423

Query: 433 VWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVL 492
           VWP+PEV+DPFRF P + +     AF+PFS G RNCIG+ FAM E+KV   LTLLRF +L
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSH--AFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELL 481

Query: 493 PDHTE-PRRKPELVLRAEGGLWLRVEPL 519
           PD T  P     LVL+++ G+ LR+  L
Sbjct: 482 PDPTRIPIPIARLVLKSKNGIHLRLRRL 509


>gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide 1
           isoform b [Homo sapiens]
          Length = 511

 Score =  409 bits (1051), Expect = e-114
 Identities = 229/519 (44%), Positives = 312/519 (60%), Gaps = 24/519 (4%)

Query: 4   LSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGH 63
           LS SSLGLW         L+LV     L  +L    T      +   FP PP  +W  GH
Sbjct: 8   LSFSSLGLWASG------LILVLGFLKLIHLLLRRQTLAKAMDK---FPGPPT-HWLFGH 57

Query: 64  LGLIHSSEEGLL-YTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDK 122
              +   E G L    S A  F      W G +   + I+ P Y K V        PK  
Sbjct: 58  A--LEIQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD---PKAP 112

Query: 123 VFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLA 182
             Y F   W+G GLL+  G KW +HR++LTP FH+++LKPY+ +F ES  IM  KW+  A
Sbjct: 113 DVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKA 172

Query: 183 SEGSARLDMFEHISLMTLDSLQKCVFSF-DSHCQEKPSEYIAAILELSALVTKRHQQILL 241
            EG +  D+F  +  M L++L KC F   D+    + S Y  A+ +L+ L+ +R      
Sbjct: 173 REGKS-FDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQY 231

Query: 242 YIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
           + DF+Y+LTP G+RF RAC++ HD TD VI+ER+  L  + V   +Q +   + LDF+D+
Sbjct: 232 HNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNR---RHLDFLDI 288

Query: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQEL 361
           LL ++DED  KLSD D+RAE DTFMFEGHDTT SG+SW LY +A +PE+Q RCR+EV+E+
Sbjct: 289 LLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREI 348

Query: 362 LKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICL 421
           L D++    +WDDL ++ +LTMCIKES RL+PPVP V R  ++ +   DGR +P G +  
Sbjct: 349 LGDQD--FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLIS 406

Query: 422 ISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVV 481
           + ++  H N AVWPDPEV+D  RF  +N  +R P AF+PFSAGPRNCIGQ FAM+EMKVV
Sbjct: 407 MHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVV 466

Query: 482 LGLTLLRFRVLPDHTE-PRRKPELVLRAEGGLWLRVEPL 519
             + LLRF    D +  P + P+LVLR++ G  L ++PL
Sbjct: 467 TAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPL 505


>gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide 1
           isoform a [Homo sapiens]
          Length = 512

 Score =  405 bits (1042), Expect = e-113
 Identities = 228/520 (43%), Positives = 310/520 (59%), Gaps = 25/520 (4%)

Query: 4   LSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGH 63
           LS SSLGLW         L+LV     L  +L    T      +   FP PP  +W  GH
Sbjct: 8   LSFSSLGLWASG------LILVLGFLKLIHLLLRRQTLAKAMDK---FPGPPT-HWLFGH 57

Query: 64  LGLIHSSEEGLL-YTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDK 122
              +   E G L    S A  F      W G +   + I+ P Y K V        PK  
Sbjct: 58  A--LEIQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD---PKAP 112

Query: 123 VFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLA 182
             Y F   W+G GLL+  G KW +HR++LTP FH+++LKPY+ +F ES  IM  KW+  A
Sbjct: 113 DVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKA 172

Query: 183 SEGSARLDMFEHISLMTLDSLQKCVFSFDSHC--QEKPSEYIAAILELSALVTKRHQQIL 240
            EG +  D+F  +  M L++L KC F          + S Y  A+ +L+ L+ +R     
Sbjct: 173 REGKS-FDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQ 231

Query: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300
            + DF+Y+LTP G+RF RAC++ HD TD VI+ER+  L  + V   +Q +   + LDF+D
Sbjct: 232 YHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNR---RHLDFLD 288

Query: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
           +LL ++DED  KLSD D+RAE DTFMFEGHDTT SG+SW LY +A +PE+Q RCR+EV+E
Sbjct: 289 ILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVRE 348

Query: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420
           +L D++    +WDDL ++ +LTMCIKES RL+PPVP V R  ++ +   DGR +P G + 
Sbjct: 349 ILGDQD--FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 406

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
            + ++  H N AVWPDPEV+D  RF  +N  +R P AF+PFSAGPRNCIGQ FAM+EMKV
Sbjct: 407 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 466

Query: 481 VLGLTLLRFRVLPDHTE-PRRKPELVLRAEGGLWLRVEPL 519
           V  + LLRF    D +  P + P+LVLR++ G  L ++PL
Sbjct: 467 VTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPL 506


>gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide 22
           [Homo sapiens]
          Length = 519

 Score =  403 bits (1035), Expect = e-112
 Identities = 228/503 (45%), Positives = 308/503 (61%), Gaps = 23/503 (4%)

Query: 20  LLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGLLYTQS 79
           LLLLL+ A+ L      W          L+ FP PP  +W  GH+      +E L   Q 
Sbjct: 27  LLLLLIKAAQLYLH-RQWLLK------ALQQFPCPPS-HWLFGHIQEFQHDQE-LQRIQE 77

Query: 80  LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLS 139
              TF   C +W+      V+++ P Y+K +L       PK    Y FL P +G GLLL 
Sbjct: 78  RVKTFPSACPYWIWGGKVRVQLYDPDYMKVIL---GRSDPKSHGSYKFLAPRIGYGLLLL 134

Query: 140 AGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMT 199
            G+ W +HRRMLTPAFH +ILKPY+ +  +SV +M  KW+ L  + S  L++F+H+SLMT
Sbjct: 135 NGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSP-LEVFQHVSLMT 193

Query: 200 LDSLQKCVFSFDSHCQ--EKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFR 257
           LD++ K  FS     Q       YI AI +L++LV    +      D +Y LT  G+   
Sbjct: 194 LDTIMKSAFSHQGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTH 253

Query: 258 RACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDED 317
           RAC+L H  TD VIQ R+  L  +G    L+   + + LDF+D+LLL+K E+G  LSD+D
Sbjct: 254 RACQLAHQHTDQVIQLRKAQLQKEGE---LEKIKRKRHLDFLDILLLAKMENGSILSDKD 310

Query: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQ 377
           +RAE DTFMFEGHDTTASG+SW+LY LA HP++QERCR+E+  LL D     I W+ L Q
Sbjct: 311 LRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGD--GASITWNHLDQ 368

Query: 378 LPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDP 437
           +P+ TMCIKE+LRL+PPVP + R  +  +  PDGR +PKGI+ L+S++G HHNP VWP+ 
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNL 428

Query: 438 EVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTE 497
           EV+DP RF P + +     AF+PFS G RNCIG+ FAM ++KV   LTLLRF +LPD T 
Sbjct: 429 EVFDPSRFAPGSAQHSH--AFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTR 486

Query: 498 -PRRKPELVLRAEGGLWLRVEPL 519
            P     LVL+++ G+ LR+  L
Sbjct: 487 IPIPMARLVLKSKNGIHLRLRRL 509


>gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide 1
           [Homo sapiens]
          Length = 509

 Score =  397 bits (1020), Expect = e-110
 Identities = 200/476 (42%), Positives = 296/476 (62%), Gaps = 14/476 (2%)

Query: 48  LRCFPQPPKRNWFLGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYI 107
           LR FP PP  +WFLGH   I   ++ +   + +   +     +W+GP+ A   I+ P Y 
Sbjct: 43  LRPFPAPPT-HWFLGHQKFIQ--DDNMEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYA 99

Query: 108 KPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIF 167
           K +L   +   PK +    F  P LG GL    G KW +HRR+LTP FHFNILK Y+++ 
Sbjct: 100 KTLL---SRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIEVM 156

Query: 168 NESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSE--YIAAI 225
             SV +M  KW+ + S     ++++EHI+ M+LD + KC FS +++CQ   +   Y  AI
Sbjct: 157 AHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAKAI 216

Query: 226 LELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDD 285
            ELS ++  R   +L + D ++ L+P G RF++  R+++ +TD +IQER+++L +    D
Sbjct: 217 FELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQAGVKQD 276

Query: 286 FLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLA 345
                 K K  DF+D++L +KDE G   SD D+ +E  TF+  GHDT A+ +SW+LY LA
Sbjct: 277 ---NTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLA 333

Query: 346 KHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQD 405
            +PE+QERCR+EV+ +L D     I WD L ++ + TMCIKE+ RL P VP++SR  ++ 
Sbjct: 334 LNPEHQERCREEVRGILGDGS--SITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKP 391

Query: 406 IVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGP 465
           +  PDG  +P GI  ++S++G HHNPAVW +P+V+DP RF  +N  +R P A++PFSAG 
Sbjct: 392 LTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGS 451

Query: 466 RNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKP-ELVLRAEGGLWLRVEPLS 520
           RNCIGQ FAM E+KV + L LL FRV PD T P   P   +L+ + G++L ++ LS
Sbjct: 452 RNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKKLS 507


>gi|30023836 cytochrome P450 4Z1 [Homo sapiens]
          Length = 505

 Score =  370 bits (950), Expect = e-102
 Identities = 202/505 (40%), Positives = 301/505 (59%), Gaps = 16/505 (3%)

Query: 11  LWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSS 70
           L  + A P+LLL+L+  S LL +++            L  FP PP  +WF GH       
Sbjct: 6   LQELMAHPFLLLILLCMSLLLFQVIRLYQRRRWMIRALHLFPAPPA-HWFYGHKEFYPVK 64

Query: 71  EEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKP 130
           E  + +   L   +      WVGP+     +  P Y K +L       PK  V +  L+ 
Sbjct: 65  EFEVYH--KLMEKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQD---PKSAVSHKILES 119

Query: 131 WLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLD 190
           W+G GL+   G KW +HR+++ P F+ +ILK ++ + +ESV +M  KW+   ++ S RL+
Sbjct: 120 WVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNS-RLE 178

Query: 191 MFEHISLMTLDSLQKCVFSFDSHCQEKPS--EYIAAILELSALVTKRHQQILLYIDFLYY 248
           +F+H+SLMTLDS+ KC FS     Q   +   Y+ A+  LS +  +R    L + D ++ 
Sbjct: 179 LFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFK 238

Query: 249 LTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDE 308
            +  GQ F +  + +H FT+ VIQ+R+ +L     D   Q   + +  DF+D+LL +K E
Sbjct: 239 FSSQGQIFSKFNQELHQFTEKVIQDRKESLK----DKLKQDTTQKRRWDFLDILLSAKSE 294

Query: 309 DGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPK 368
           + K  S+ D++AE  TFMF GHDTT+S +SW+LY LAK+PE+Q+RCR E++ELL D    
Sbjct: 295 NTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGS-- 352

Query: 369 EIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTH 428
            I W+ L+Q+P+ TMCIKE LRL+ PV  +SR   + I  PDGR +P GI   I+++  H
Sbjct: 353 SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALH 412

Query: 429 HNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLR 488
           HNP  W DP+V++P RF  +N ++  P AFIPFSAG RNCIGQ FA+ E KV + LTLLR
Sbjct: 413 HNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLR 472

Query: 489 FRVLPDHTEPRRK-PELVLRAEGGL 512
           F++ PDH+ P +   ++VL+++ G+
Sbjct: 473 FKLAPDHSRPPQPVRQVVLKSKNGI 497


>gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide 2
           [Homo sapiens]
          Length = 525

 Score =  275 bits (703), Expect = 7e-74
 Identities = 158/434 (36%), Positives = 250/434 (57%), Gaps = 15/434 (3%)

Query: 91  WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
           WVGP   +V +++   ++ +L +   I       Y FL+PWLG GLL S G KW   R+M
Sbjct: 93  WVGPV-PMVALYNAENVEVILTSSKQIDKSS--MYKFLEPWLGLGLLTSTGNKWRSRRKM 149

Query: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
           LTP FHF IL+ ++ I NE  NI+  K +   ++ +   + F +I+L  LD + +     
Sbjct: 150 LTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEA--FNCFFYITLCALDIICETAMGK 207

Query: 211 DSHCQEKP-SEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDA 269
           +   Q    SEY+ A+  +S ++ +R +   L++D  Y +  +G   +++ +++H FT++
Sbjct: 208 NIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTNS 267

Query: 270 VIQERRRTLPSQGV---DDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFM 326
           VI ER   + +      D    A +K+K   F+D+LL   D++G +LS EDIR E DTFM
Sbjct: 268 VIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFM 327

Query: 327 FEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL-KDREPKEIEWDDLAQLPFLTMCI 385
           FEGHDTTA+ ++W LY L  +PE Q++   E+ ++  K   P  +E  DL +L +L   I
Sbjct: 328 FEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVE--DLKKLRYLECVI 385

Query: 386 KESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF 445
           KE+LRL P VP  +R  ++D  +   RV+ KG   +I  +  H +P  +P+PE + P RF
Sbjct: 386 KETLRLFPSVPLFARSVSEDCEVAGYRVL-KGTEAVIIPYALHRDPRYFPNPEEFQPERF 444

Query: 446 DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPD--HTEPRRKPE 503
            P+N + R P A++PFSAGPRNCIGQ FA+ E K +L   L  F +  +    E   + +
Sbjct: 445 FPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQ 504

Query: 504 LVLRAEGGLWLRVE 517
           L+LR   G+W++++
Sbjct: 505 LILRPSNGIWIKLK 518


>gi|239757171 PREDICTED: similar to cytochrome P450, family 4,
           subfamily F, polypeptide 2 [Homo sapiens]
          Length = 190

 Score =  263 bits (672), Expect = 3e-70
 Identities = 129/157 (82%), Positives = 142/157 (90%)

Query: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFS 209
           ML PAFHFNILKPYMKIF+ESVNIMHAKW LL  E +A LDMFEH++LMTLDSLQKCVFS
Sbjct: 1   MLMPAFHFNILKPYMKIFDESVNIMHAKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFS 60

Query: 210 FDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDA 269
           FDS CQEKPSEYIA++LELS+LV KR+QQILL++DFLYYLT DG+ F RACRL HDF DA
Sbjct: 61  FDSQCQEKPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADA 120

Query: 270 VIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
            IQE+R TLPSQGVDDFLQAKAKSKTLDFIDVLL+SK
Sbjct: 121 AIQEKRHTLPSQGVDDFLQAKAKSKTLDFIDVLLISK 157


>gi|239751683 PREDICTED: similar to cytochrome P450, family 4,
           subfamily F, polypeptide 2 [Homo sapiens]
          Length = 190

 Score =  263 bits (672), Expect = 3e-70
 Identities = 129/157 (82%), Positives = 142/157 (90%)

Query: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFS 209
           ML PAFHFNILKPYMKIF+ESVNIMHAKW LL  E +A LDMFEH++LMTLDSLQKCVFS
Sbjct: 1   MLMPAFHFNILKPYMKIFDESVNIMHAKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFS 60

Query: 210 FDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDA 269
           FDS CQEKPSEYIA++LELS+LV KR+QQILL++DFLYYLT DG+ F RACRL HDF DA
Sbjct: 61  FDSQCQEKPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADA 120

Query: 270 VIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
            IQE+R TLPSQGVDDFLQAKAKSKTLDFIDVLL+SK
Sbjct: 121 AIQEKRHTLPSQGVDDFLQAKAKSKTLDFIDVLLISK 157


>gi|239746187 PREDICTED: similar to cytochrome P450, family 4,
           subfamily F, polypeptide 2 [Homo sapiens]
          Length = 190

 Score =  263 bits (672), Expect = 3e-70
 Identities = 129/157 (82%), Positives = 142/157 (90%)

Query: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFS 209
           ML PAFHFNILKPYMKIF+ESVNIMHAKW LL  E +A LDMFEH++LMTLDSLQKCVFS
Sbjct: 1   MLMPAFHFNILKPYMKIFDESVNIMHAKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFS 60

Query: 210 FDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDA 269
           FDS CQEKPSEYIA++LELS+LV KR+QQILL++DFLYYLT DG+ F RACRL HDF DA
Sbjct: 61  FDSQCQEKPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADA 120

Query: 270 VIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
            IQE+R TLPSQGVDDFLQAKAKSKTLDFIDVLL+SK
Sbjct: 121 AIQEKRHTLPSQGVDDFLQAKAKSKTLDFIDVLLISK 157


>gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7
           [Homo sapiens]
          Length = 503

 Score =  155 bits (392), Expect = 8e-38
 Identities = 116/400 (29%), Positives = 199/400 (49%), Gaps = 34/400 (8%)

Query: 131 WLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLD 190
           ++ + + ++  E+W R R +L+P F    LK  + I  +  +++    +  A  G   + 
Sbjct: 113 FMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKP-VT 171

Query: 191 MFEHISLMTLDSLQKCVF--SFDS--HCQEKPSEYIAAILELSALVTKRHQQILLYIDFL 246
           +       ++D +    F  S DS  + Q+   E    +L  + L        +L I   
Sbjct: 172 LKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPL-----DPFVLSIKVF 226

Query: 247 YYLTPDGQRFRRAC---RLVHDFTDAV--IQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
            +LTP  +         +++   T +V  I+E R     +   DFLQ    S+       
Sbjct: 227 PFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQN------ 280

Query: 302 LLLSKD-EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360
              SKD E  K LSD ++ A++  F+F G++TT+S LS+++Y LA HP+ Q++ ++E+  
Sbjct: 281 ---SKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDT 337

Query: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420
           +L ++ P    +D + QL +L M + E+LRL P    + R C +D+ + +G  IPKG++ 
Sbjct: 338 VLPNKAPPT--YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI-NGMFIPKGVVV 394

Query: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           +I  +  HH+P  W +PE + P RF  KN     P  + PF +GPRNCIG  FA+  MK+
Sbjct: 395 MIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKL 454

Query: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAE-GGLWLRVEPL 519
            L   L  F       +P ++ ++ L+   GGL L  +P+
Sbjct: 455 ALVRVLQNFSF-----KPCKETQIPLKLRFGGLLLTEKPI 489


>gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 2 [Homo sapiens]
          Length = 503

 Score =  155 bits (391), Expect = 1e-37
 Identities = 114/420 (27%), Positives = 200/420 (47%), Gaps = 30/420 (7%)

Query: 84  FGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEK 143
           +G+M   + G    +V I  P  IK VL      V  +++    +  +L   L  +  E+
Sbjct: 68  YGEMWGLYEGQQPMLV-IMDPDMIKTVLVKECYSVFTNQMPLGPMG-FLKSALSFAEDEE 125

Query: 144 WSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSL 203
           W R R +L+PAF     K  + I ++  +++    +  A E S  +++ +     T+D +
Sbjct: 126 WKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEA-ENSKSINLKDFFGAYTMDVI 184

Query: 204 QKCVFSFDSHCQEKPSE----YIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRF--- 256
              +F  +      P +     +  +L+L  L        LL I    +LTP  +     
Sbjct: 185 TGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFL-----DPFLLLISLFPFLTPVFEALNIG 239

Query: 257 ---RRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKL 313
              +     + +  + + + R +      VD F Q          ID     + +  K L
Sbjct: 240 LFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQ---------MIDSQNSKETKSHKAL 290

Query: 314 SDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWD 373
           SD ++ A++   +F  +DTT++ L +++Y LA HP+ Q++ ++E+  +L ++ P  + +D
Sbjct: 291 SDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAP--VTYD 348

Query: 374 DLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAV 433
            L Q+ +L M + E+LRL P V  V+R C +DI + +G  IPKG+  ++ ++  HH+P  
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-NGVFIPKGLAVMVPIYALHHDPKY 407

Query: 434 WPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLP 493
           W +PE + P RF  KN        +IPF AGPRNCIG  FA+  +K+ +   L  F   P
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467


>gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 1 [Homo sapiens]
          Length = 504

 Score =  150 bits (380), Expect = 2e-36
 Identities = 114/421 (27%), Positives = 200/421 (47%), Gaps = 31/421 (7%)

Query: 84  FGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEK 143
           +G+M   + G    +V I  P  IK VL      V  +++    +  +L   L  +  E+
Sbjct: 68  YGEMWGLYEGQQPMLV-IMDPDMIKTVLVKECYSVFTNQMPLGPMG-FLKSALSFAEDEE 125

Query: 144 WSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSL 203
           W R R +L+PAF     K  + I ++  +++    +  A E S  +++ +     T+D +
Sbjct: 126 WKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEA-ENSKSINLKDFFGAYTMDVI 184

Query: 204 QKCVFSFDSHCQEKPSE----YIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRF--- 256
              +F  +      P +     +  +L+L  L        LL I    +LTP  +     
Sbjct: 185 TGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFL-----DPFLLLISLFPFLTPVFEALNIG 239

Query: 257 ---RRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKL 313
              +     + +  + + + R +      VD F Q          ID     + +  K L
Sbjct: 240 LFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQ---------MIDSQNSKETKSHKAL 290

Query: 314 SDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWD 373
           SD ++ A++   +F  +DTT++ L +++Y LA HP+ Q++ ++E+  +L ++ P  + +D
Sbjct: 291 SDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAP--VTYD 348

Query: 374 DLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAV 433
            L Q+ +L M + E+LRL P V  V+R C +DI + +G  IPKG+  ++ ++  HH+P  
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-NGVFIPKGLAVMVPIYALHHDPKY 407

Query: 434 WPDPEVYDP-FRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVL 492
           W +PE + P  RF  KN        +IPF AGPRNCIG  FA+  +K+ +   L  F   
Sbjct: 408 WTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 467

Query: 493 P 493
           P
Sbjct: 468 P 468


>gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide 4
           [Homo sapiens]
          Length = 503

 Score =  147 bits (371), Expect = 2e-35
 Identities = 99/371 (26%), Positives = 179/371 (48%), Gaps = 24/371 (6%)

Query: 131 WLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLD 190
           ++   + ++  E+W R R +L+P F    LK  + I  +  +++    +  A  G   + 
Sbjct: 113 FMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKP-VT 171

Query: 191 MFEHISLMTLDSLQKCVFSFDSHCQEKPS----EYIAAILELSALVTKRHQQILLYIDFL 246
           + +     ++D +    F  +      P     E    +L    L         L I   
Sbjct: 172 LKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFL-----DPFFLSITVF 226

Query: 247 YYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
            +L P  +     C    + T+ + +  +R   S+  D       +   +DF+ +++ S+
Sbjct: 227 PFLIPILEVLN-ICVFPREVTNFLRKSVKRMKESRLED------TQKHRVDFLQLMIDSQ 279

Query: 307 D----EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362
           +    E  K LSD ++ A++  F+F G++TT+S LS+++Y LA HP+ Q++ ++E+  +L
Sbjct: 280 NSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVL 339

Query: 363 KDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLI 422
            ++ P    +D + Q+ +L M + E+LRL P    + R C +D+ + +G  IPKG++ +I
Sbjct: 340 PNKAPPT--YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-NGMFIPKGVVVMI 396

Query: 423 SVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482
             +  H +P  W +PE + P RF  KN     P  + PF +GPRNCIG  FA+  MK+ L
Sbjct: 397 PSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLAL 456

Query: 483 GLTLLRFRVLP 493
              L  F   P
Sbjct: 457 IRVLQNFSFKP 467


>gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5
           [Homo sapiens]
          Length = 502

 Score =  142 bits (359), Expect = 6e-34
 Identities = 104/371 (28%), Positives = 178/371 (47%), Gaps = 25/371 (6%)

Query: 131 WLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLD 190
           ++   + L+  E+W R R +L+P F    LK    I  +  +++    +  A +G   + 
Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKP-VT 171

Query: 191 MFEHISLMTLDSLQKCVFSFDSHCQEKPS----EYIAAILELSALVTKRHQQILLYIDFL 246
           + +     ++D +    F  +      P     E     L+   L       + L I   
Sbjct: 172 LKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFL-----DPLFLSIILF 226

Query: 247 YYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSK 306
            +LTP  +    +     D  + + +   R   S+     L  K K + LDF+ +++ S+
Sbjct: 227 PFLTPVFEALNVSL-FPKDTINFLSKSVNRMKKSR-----LNDKQKHR-LDFLQLMIDSQ 279

Query: 307 D----EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362
           +    E  K LSD ++ A++  F+F G++TT+S LS+ LY LA HP+ Q++ ++E+  +L
Sbjct: 280 NSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVL 339

Query: 363 KDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLI 422
            ++ P    +D + Q+ +L M + E+LRL P    + R C +D+ + +G  IPKG + +I
Sbjct: 340 PNKAPP--TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-NGVFIPKGSMVVI 396

Query: 423 SVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482
             +  HH+P  W +PE + P RF  K      P  + PF  GPRNCIG  FA+  MK+ L
Sbjct: 397 PTYALHHDPKYWTEPEEFRPERFSKKK-DSIDPYIYTPFGTGPRNCIGMRFALMNMKLAL 455

Query: 483 GLTLLRFRVLP 493
              L  F   P
Sbjct: 456 IRVLQNFSFKP 466


>gi|5729796 cytochrome P450, family 46 [Homo sapiens]
          Length = 500

 Score =  141 bits (356), Expect = 1e-33
 Identities = 137/497 (27%), Positives = 226/497 (45%), Gaps = 62/497 (12%)

Query: 22  LLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGLLYTQSLA 81
           LLL+G++ LLA  L  T+       R    P PP+ ++ LGHL      +E  +  + L 
Sbjct: 5   LLLLGSAVLLAFGLCCTFVHRARS-RYEHIPGPPRPSFLLGHLPCFWKKDE--VGGRVLQ 61

Query: 82  CTFGDMCCWWVGPWHAIVRI--FHPTYIKPVLFAPAAIVP--------KDKVFYSFLKPW 131
             F D    W   +  +VR+  FH T +  ++ +P ++          KD   Y  L+  
Sbjct: 62  DVFLD----WAKKYGPVVRVNVFHKTSV--IVTSPESVKKFLMSTKYNKDSKMYRALQTV 115

Query: 132 LGD-----GLLLSAG-EKWSRHRRMLTPAFHFNILKPYMKIFNES----VNIMHAKWQLL 181
            G+     GL+     E+W + RR++  AF  + L   M+ FNE     V I+ AK    
Sbjct: 116 FGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAK---- 171

Query: 182 ASEGSARLDMFEHISLMTLDSLQKCVFSFDSHC---QEKPSEYIAAILELSALVTKRHQQ 238
            ++G   + M + ++   +D L K  F  ++      +KP    A  L L  +   R+  
Sbjct: 172 -ADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQ-AVKLMLEGITASRNT- 228

Query: 239 ILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDF 298
                 FL       +  R + R +       +Q RR  L           + +    D 
Sbjct: 229 ---LAKFLPGKRKQLREVRESIRFLRQVGRDWVQRRREALK----------RGEEVPADI 275

Query: 299 IDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEV 358
           +  +L  K E+G +  DE +     TF   GH+T+A+ L++ +  L++ PE   R + EV
Sbjct: 276 LTQIL--KAEEGAQ-DDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEV 332

Query: 359 QELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGI 418
            E++  +  + ++++DL +L +L+  +KESLRL+PP     R   ++ ++ DG  +P   
Sbjct: 333 DEVIGSK--RYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI-DGVRVPGNT 389

Query: 419 ICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEM 478
             L S +        + DP  ++P RF P   K R    + PFS G R+CIGQ FA  E+
Sbjct: 390 PLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPR--FTYFPFSLGHRSCIGQQFAQMEV 447

Query: 479 KVVLG--LTLLRFRVLP 493
           KVV+   L  L FR++P
Sbjct: 448 KVVMAKLLQRLEFRLVP 464


>gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 3 [Homo sapiens]
          Length = 420

 Score =  118 bits (296), Expect = 1e-26
 Identities = 94/371 (25%), Positives = 175/371 (47%), Gaps = 30/371 (8%)

Query: 84  FGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEK 143
           +G+M   + G    +V I  P  IK VL      V  +++    +  +L   L  +  E+
Sbjct: 68  YGEMWGLYEGQQPMLV-IMDPDMIKTVLVKECYSVFTNQMPLGPMG-FLKSALSFAEDEE 125

Query: 144 WSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSL 203
           W R R +L+PAF     K  + I ++  +++    +  A E S  +++ +     T+D +
Sbjct: 126 WKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEA-ENSKSINLKDFFGAYTMDVI 184

Query: 204 QKCVFSFDSHCQEKPSE----YIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRF--- 256
              +F  +      P +     +  +L+L  L        LL I    +LTP  +     
Sbjct: 185 TGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFL-----DPFLLLISLFPFLTPVFEALNIG 239

Query: 257 ---RRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKL 313
              +     + +  + + + R +      VD F Q          ID     + +  K L
Sbjct: 240 LFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQ---------MIDSQNSKETKSHKAL 290

Query: 314 SDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWD 373
           SD ++ A++   +F  +DTT++ L +++Y LA HP+ Q++ ++E+  +L ++ P  + +D
Sbjct: 291 SDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAP--VTYD 348

Query: 374 DLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAV 433
            L Q+ +L M + E+LRL P V  V+R C +DI + +G  IPKG+  ++ ++  HH+P  
Sbjct: 349 ALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-NGVFIPKGLAVMVPIYALHHDPKY 407

Query: 434 WPDPEVYDPFR 444
           W +PE + P R
Sbjct: 408 WTEPEKFCPER 418


>gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score =  115 bits (287), Expect = 1e-25
 Identities = 125/504 (24%), Positives = 219/504 (43%), Gaps = 62/504 (12%)

Query: 55  PKRNWFLGHLGLIHSSEEGLLYTQ-SLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFA 113
           PK + F+G+L       +G   +Q  L   +G +C +++G    IV I  P  IK VL  
Sbjct: 48  PKPSPFIGNLTFFR---QGFWESQMELRKLYGPLCGYYLGRRMFIV-ISEPDMIKQVLVE 103

Query: 114 PAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNI 173
             +            K  + D +L    ++W   R  L  AF    L   + + +++ ++
Sbjct: 104 NFSNFTNRMASGLEFKS-VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDL 162

Query: 174 MHAKWQLLASEGSA----------RLDMFEHISLMT-LDSLQKCVFSFDSHCQEK----- 217
           + A  +  A  G A            D+   ++  T +DS Q     F  HC+       
Sbjct: 163 LLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCI 222

Query: 218 PSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQR------FRRACRLVHDFTDAVI 271
           P   +  +L   +++             L  + P+  R      F +  R V    D   
Sbjct: 223 PRPILVLLLSFPSIMVP-----------LARILPNKNRDELNGFFNKLIRNVIALRDQQA 271

Query: 272 QERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKK---------------LSDE 316
            E RR    Q V D   + +     DF D++       G K               L+ +
Sbjct: 272 AEERRRDFLQMVLDARHSASPMGVQDF-DIVRDVFSSTGCKPNPSRQHQPSPMARPLTVD 330

Query: 317 DIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLA 376
           +I  +A  F+  G++   + LS+  Y LA +P+ QE+  +EV ++ K++     E+  L 
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAP-EFCSLE 388

Query: 377 Q-LPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWP 435
           + LP+L M I E+LR++PP    +R   QD  +  G+ IP G +  ++V   HH+P  WP
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL-GQRIPAGAVLEMAVGALHHDPEHWP 447

Query: 436 DPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVL--GLTLLRFRVLP 493
            PE ++P RF  +  ++  P  ++PF AGPR+C+G    + E+K+ L   L   RF+  P
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507

Query: 494 DHTEP-RRKPELVLRAEGGLWLRV 516
           +   P + + +  L  + G+++++
Sbjct: 508 ETQVPLQLESKSALGPKNGVYIKI 531


>gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score =  115 bits (287), Expect = 1e-25
 Identities = 125/504 (24%), Positives = 219/504 (43%), Gaps = 62/504 (12%)

Query: 55  PKRNWFLGHLGLIHSSEEGLLYTQ-SLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFA 113
           PK + F+G+L       +G   +Q  L   +G +C +++G    IV I  P  IK VL  
Sbjct: 48  PKPSPFIGNLTFFR---QGFWESQMELRKLYGPLCGYYLGRRMFIV-ISEPDMIKQVLVE 103

Query: 114 PAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNI 173
             +            K  + D +L    ++W   R  L  AF    L   + + +++ ++
Sbjct: 104 NFSNFTNRMASGLEFKS-VADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDL 162

Query: 174 MHAKWQLLASEGSA----------RLDMFEHISLMT-LDSLQKCVFSFDSHCQEK----- 217
           + A  +  A  G A            D+   ++  T +DS Q     F  HC+       
Sbjct: 163 LLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCI 222

Query: 218 PSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQR------FRRACRLVHDFTDAVI 271
           P   +  +L   +++             L  + P+  R      F +  R V    D   
Sbjct: 223 PRPILVLLLSFPSIMVP-----------LARILPNKNRDELNGFFNKLIRNVIALRDQQA 271

Query: 272 QERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKK---------------LSDE 316
            E RR    Q V D   + +     DF D++       G K               L+ +
Sbjct: 272 AEERRRDFLQMVLDARHSASPMGVQDF-DIVRDVFSSTGCKPNPSRQHQPSPMARPLTVD 330

Query: 317 DIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLA 376
           +I  +A  F+  G++   + LS+  Y LA +P+ QE+  +EV ++ K++     E+  L 
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAP-EFCSLE 388

Query: 377 Q-LPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWP 435
           + LP+L M I E+LR++PP    +R   QD  +  G+ IP G +  ++V   HH+P  WP
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL-GQRIPAGAVLEMAVGALHHDPEHWP 447

Query: 436 DPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVL--GLTLLRFRVLP 493
            PE ++P RF  +  ++  P  ++PF AGPR+C+G    + E+K+ L   L   RF+  P
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACP 507

Query: 494 DHTEP-RRKPELVLRAEGGLWLRV 516
           +   P + + +  L  + G+++++
Sbjct: 508 ETQVPLQLESKSALGPKNGVYIKI 531


>gi|4503211 cytochrome P450, family 27, subfamily A, polypeptide 1
           precursor [Homo sapiens]
          Length = 531

 Score =  107 bits (267), Expect = 3e-23
 Identities = 97/382 (25%), Positives = 170/382 (44%), Gaps = 40/382 (10%)

Query: 147 HRRMLTPAFHFNILKP-----YMKIFNESVNIMHAKWQLLASE---GSARLDMFEHISLM 198
           H   L  A +  +LKP     Y   FNE ++    +   L +E   G+   DM +     
Sbjct: 153 HWYQLRQALNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQLFYYF 212

Query: 199 TLDSLQKCVFSFDSHCQEK--PSEYIAAILELSALVTKRHQQILLYIDFLYYLT----PD 252
            L+++   +F     C ++  P + +  +  +  +      Q  LY  FL   T    P 
Sbjct: 213 ALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMF-----QNSLYATFLPKWTRPVLPF 267

Query: 253 GQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKS--KTLDFIDVLLLSKDEDG 310
            +R+      +  F   +I E+   + +Q     LQA      +   ++  LL S     
Sbjct: 268 WKRYLDGWNAIFSFGKKLIDEKLEDMEAQ-----LQAAGPDGIQVSGYLHFLLASG---- 318

Query: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
            +LS  +        +  G DTT++ L+W LYHL+K PE QE   +EV  ++   +  + 
Sbjct: 319 -QLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQH 377

Query: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHN 430
           +  D A +P L   +KE+LRL+P VP  SR   ++I + DG + PK    +   +    +
Sbjct: 378 K--DFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV-DGFLFPKNTQFVFCHYVVSRD 434

Query: 431 PAVWPDPEVYDPFRF----DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTL 486
           P  + +PE + P R+     P   + + P   +PF  G R C+G+  A  EM+++L   +
Sbjct: 435 PTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLI 494

Query: 487 LRFRVL--PDHTEPRRKPELVL 506
            +++V+  P+  E +    +VL
Sbjct: 495 QKYKVVLAPETGELKSVARIVL 516


>gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide 1
           [Homo sapiens]
          Length = 501

 Score =  103 bits (257), Expect = 4e-22
 Identities = 120/494 (24%), Positives = 205/494 (41%), Gaps = 65/494 (13%)

Query: 51  FPQPPKRNWFLGHL-GLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKP 109
           FP  P    F+G++  L  SSE   +Y +  +  +G++    +G    +V   +   +K 
Sbjct: 39  FPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDV-VKE 97

Query: 110 VLFAPAAIVPKDKVFYSFLKPWLGDGLLLSA-GEKWSRHRRMLTPAFHF----------N 158
            L   + I         F+K     GLL S  G  W  HRR+   +F +           
Sbjct: 98  CLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESK 157

Query: 159 ILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCV-----FSFDSH 213
           IL+   K FN+++                R   F+ +    + ++   +     F+++  
Sbjct: 158 ILEE-TKFFNDAIETY-----------KGRPFDFKQLITNAVSNITNLIIFGERFTYEDT 205

Query: 214 CQEKPSEYIAAILELSALVTKRHQQILLYIDFLYY-LTPDG---QRFRRACRLVHDFTDA 269
             +   E  +  +EL+A  +     + LY  F +  + P G   Q FR A  +V+DF   
Sbjct: 206 DFQHMIELFSENVELAASAS-----VFLYNAFPWIGILPFGKHQQLFRNAA-VVYDFLSR 259

Query: 270 VIQE----RRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTF 325
           +I++    R+  LP   VD +L            D +   K++     S E++       
Sbjct: 260 LIEKASVNRKPQLPQHFVDAYL------------DEMDQGKNDPSSTFSKENLIFSVGEL 307

Query: 326 MFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCI 385
           +  G +TT + L W +  +A +P  Q + ++E+ +L+     K   WDD  ++P+    +
Sbjct: 308 IIAGTETTTNVLRWAILFMALYPNIQGQVQKEI-DLIMGPNGKP-SWDDKCKMPYTEAVL 365

Query: 386 KESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF 445
            E LR    VP      T +  +  G  IPKG   + +++  H +   W DPEV+ P RF
Sbjct: 366 HEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERF 425

Query: 446 DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRV-LPDHTEPRRKPEL 504
              +       A +PFS G R+C+G+  A  EM +     L RF +  P    P  KP L
Sbjct: 426 LDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPDLKPRL 485

Query: 505 VLRAEGGLWLRVEP 518
                 G+ L+ +P
Sbjct: 486 ------GMTLQPQP 493


>gi|16933528 cytochrome P450, family 26, subfamily A, polypeptide 1
           isoform 2 [Homo sapiens]
          Length = 428

 Score =  102 bits (253), Expect = 1e-21
 Identities = 57/187 (30%), Positives = 105/187 (56%), Gaps = 4/187 (2%)

Query: 297 DFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQ 356
           D + +L+    E G++L  + ++  +   +F GH+TTAS  + ++ +L  +P   ++ R+
Sbjct: 200 DALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVRE 259

Query: 357 EVQE---LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRV 413
           E++    L K  +  +++ + L QL ++   IKE+LRL+PPVP   R   +   L +G  
Sbjct: 260 ELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQ 318

Query: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAF 473
           IPKG   + S+  TH    ++ + E ++P RF   + ++ S  +FIPF  G R+C+G+ F
Sbjct: 319 IPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEF 378

Query: 474 AMAEMKV 480
           A   +K+
Sbjct: 379 AKILLKI 385


>gi|16933530 cytochrome P450, family 26, subfamily A, polypeptide 1
           isoform 1 [Homo sapiens]
          Length = 497

 Score =  102 bits (253), Expect = 1e-21
 Identities = 57/187 (30%), Positives = 105/187 (56%), Gaps = 4/187 (2%)

Query: 297 DFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQ 356
           D + +L+    E G++L  + ++  +   +F GH+TTAS  + ++ +L  +P   ++ R+
Sbjct: 269 DALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVRE 328

Query: 357 EVQE---LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRV 413
           E++    L K  +  +++ + L QL ++   IKE+LRL+PPVP   R   +   L +G  
Sbjct: 329 ELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQ 387

Query: 414 IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAF 473
           IPKG   + S+  TH    ++ + E ++P RF   + ++ S  +FIPF  G R+C+G+ F
Sbjct: 388 IPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEF 447

Query: 474 AMAEMKV 480
           A   +K+
Sbjct: 448 AKILLKI 454


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,737,388
Number of Sequences: 37866
Number of extensions: 1023621
Number of successful extensions: 3145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2879
Number of HSP's gapped (non-prelim): 112
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.