Guide to the Human Genome
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Search of human proteins with 239754214

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239754214 PREDICTED: similar to leucocyte elastase inhibitor
[Homo sapiens]
         (141 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754214 PREDICTED: similar to leucocyte elastase inhibitor ...   295   6e-81
gi|239748736 PREDICTED: hypothetical protein XP_002346785 [Homo ...   295   6e-81
gi|239742782 PREDICTED: hypothetical protein XP_002342650 [Homo ...   295   6e-81
gi|47157325 protein kinase C, delta [Homo sapiens]                     37   0.005
gi|31377782 protein kinase C, delta [Homo sapiens]                     37   0.005
gi|5031877 lamin B1 [Homo sapiens]                                     30   0.66 
gi|111955139 GTP-binding protein 10 isoform 2 [Homo sapiens]           30   0.66 
gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Hom...    29   1.5  
gi|122891872 microcephalin [Homo sapiens]                              28   1.9  
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    28   1.9  
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    28   1.9  
gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]     28   1.9  
gi|6912372 forkhead box D3 [Homo sapiens]                              28   2.5  
gi|7706515 photoreceptor-specific nuclear receptor isoform a [Ho...    27   4.3  
gi|7657395 photoreceptor-specific nuclear receptor isoform b [Ho...    27   4.3  
gi|60685227 SECIS binding protein 2-like [Homo sapiens]                27   4.3  
gi|222446611 R-spondin family, member 2 [Homo sapiens]                 27   5.6  
gi|42794265 MAS-related GPR, member D [Homo sapiens]                   27   5.6  
gi|239753832 PREDICTED: hypothetical protein XP_002345793 [Homo ...    27   7.3  
gi|239748395 PREDICTED: hypothetical protein XP_002346654 [Homo ...    27   7.3  
gi|239742323 PREDICTED: hypothetical protein XP_002342491 [Homo ...    27   7.3  
gi|150378528 G protein-coupled receptor associated sorting prote...    26   9.5  
gi|150378489 G protein-coupled receptor associated sorting prote...    26   9.5  
gi|103472136 G protein-coupled receptor associated sorting prote...    26   9.5  
gi|10863935 reticulon 1 isoform A [Homo sapiens]                       26   9.5  
gi|6912676 SKI-interacting protein [Homo sapiens]                      26   9.5  

>gi|239754214 PREDICTED: similar to leucocyte elastase inhibitor
           [Homo sapiens]
          Length = 141

 Score =  295 bits (756), Expect = 6e-81
 Identities = 141/141 (100%), Positives = 141/141 (100%)

Query: 1   MGPLFLNCHHCTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDE 60
           MGPLFLNCHHCTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDE
Sbjct: 1   MGPLFLNCHHCTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDE 60

Query: 61  EKEGVVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRLVHDLGQRQVCLGHSREVCLA 120
           EKEGVVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRLVHDLGQRQVCLGHSREVCLA
Sbjct: 61  EKEGVVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRLVHDLGQRQVCLGHSREVCLA 120

Query: 121 QLEGISHAQVAQDTLHVVAFL 141
           QLEGISHAQVAQDTLHVVAFL
Sbjct: 121 QLEGISHAQVAQDTLHVVAFL 141


>gi|239748736 PREDICTED: hypothetical protein XP_002346785 [Homo
           sapiens]
          Length = 141

 Score =  295 bits (756), Expect = 6e-81
 Identities = 141/141 (100%), Positives = 141/141 (100%)

Query: 1   MGPLFLNCHHCTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDE 60
           MGPLFLNCHHCTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDE
Sbjct: 1   MGPLFLNCHHCTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDE 60

Query: 61  EKEGVVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRLVHDLGQRQVCLGHSREVCLA 120
           EKEGVVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRLVHDLGQRQVCLGHSREVCLA
Sbjct: 61  EKEGVVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRLVHDLGQRQVCLGHSREVCLA 120

Query: 121 QLEGISHAQVAQDTLHVVAFL 141
           QLEGISHAQVAQDTLHVVAFL
Sbjct: 121 QLEGISHAQVAQDTLHVVAFL 141


>gi|239742782 PREDICTED: hypothetical protein XP_002342650 [Homo
           sapiens]
          Length = 141

 Score =  295 bits (756), Expect = 6e-81
 Identities = 141/141 (100%), Positives = 141/141 (100%)

Query: 1   MGPLFLNCHHCTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDE 60
           MGPLFLNCHHCTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDE
Sbjct: 1   MGPLFLNCHHCTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDE 60

Query: 61  EKEGVVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRLVHDLGQRQVCLGHSREVCLA 120
           EKEGVVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRLVHDLGQRQVCLGHSREVCLA
Sbjct: 61  EKEGVVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRLVHDLGQRQVCLGHSREVCLA 120

Query: 121 QLEGISHAQVAQDTLHVVAFL 141
           QLEGISHAQVAQDTLHVVAFL
Sbjct: 121 QLEGISHAQVAQDTLHVVAFL 141


>gi|47157325 protein kinase C, delta [Homo sapiens]
          Length = 676

 Score = 37.0 bits (84), Expect = 0.005
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 6   LNCHH-CTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDEEKEG 64
           +N HH C +K   + G    +     E L+  T  +SRR  +A+ E PVG+    E+K G
Sbjct: 266 MNVHHKCREKVANLCGINQKLLA---EALNQVTQRASRRSDSASSE-PVGIYQGFEKKTG 321

Query: 65  VVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRL 100
           V G +  D SGT          C++  F+   HK L
Sbjct: 322 VAGEDMQDNSGTYGKIWEGSSKCNINNFI--FHKVL 355


>gi|31377782 protein kinase C, delta [Homo sapiens]
          Length = 676

 Score = 37.0 bits (84), Expect = 0.005
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 7/96 (7%)

Query: 6   LNCHH-CTDKATWVAGTLWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDEEKEG 64
           +N HH C +K   + G    +     E L+  T  +SRR  +A+ E PVG+    E+K G
Sbjct: 266 MNVHHKCREKVANLCGINQKLLA---EALNQVTQRASRRSDSASSE-PVGIYQGFEKKTG 321

Query: 65  VVGAEAGDESGTPHHHDGSCGGCSLRAFLIDLHKRL 100
           V G +  D SGT          C++  F+   HK L
Sbjct: 322 VAGEDMQDNSGTYGKIWEGSSKCNINNFI--FHKVL 355


>gi|5031877 lamin B1 [Homo sapiens]
          Length = 586

 Score = 30.0 bits (66), Expect = 0.66
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 7/70 (10%)

Query: 22  LWSVRGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDEEKEG-------VVGAEAGDES 74
           +W  +   G G   K  L + +G+  A+ + V    + EE+E        VV  E   + 
Sbjct: 514 IWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQ 573

Query: 75  GTPHHHDGSC 84
           GTP   + SC
Sbjct: 574 GTPRASNRSC 583


>gi|111955139 GTP-binding protein 10 isoform 2 [Homo sapiens]
          Length = 387

 Score = 30.0 bits (66), Expect = 0.66
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 4/75 (5%)

Query: 30  GEGLHTK-TALSSRRGKAAAEENPVGLAVLDEEKEGVVGAEAGDESGTPHHHDGSCGGCS 88
           G G ++K +AL   +GK      PVG++V DE   G +  E   E+       G  GG  
Sbjct: 70  GVGANSKISALKGSKGKDCEIPVPVGISVTDE--NGKIIGELNKENDRILVAQGGLGGKL 127

Query: 89  LRAFL-IDLHKRLVH 102
           L  FL +   KR++H
Sbjct: 128 LTNFLPLKGQKRIIH 142


>gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Homo
           sapiens]
          Length = 2063

 Score = 28.9 bits (63), Expect = 1.5
 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 6/65 (9%)

Query: 27  GQRGEGLHTKTALSSRRGKAAAEENPVGLAVLD------EEKEGVVGAEAGDESGTPHHH 80
           G+ GE   + +    +R +AA  E P G +V          K G+    A DE  T  H 
Sbjct: 725 GEAGEAYRSLSDPIPQRHRAATSEEPTGFSVDSNLLGSLSPKTGLPATSAMDEGLTSGHS 784

Query: 81  DGSCG 85
           D S G
Sbjct: 785 DWSVG 789


>gi|122891872 microcephalin [Homo sapiens]
          Length = 835

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 6/81 (7%)

Query: 25  VRGQRGEGLHTKTALSSRRGKAAAEENPV-----GLAVLDEEKEGVVGAEAGDESGTPHH 79
           ++  + +G  +K + SS  G+A +E  P       +    EEKE + G  +G     P  
Sbjct: 558 LKSTQNKGTTSKISNSSE-GEAQSEHEPCFIVDCNMETSTEEKENLPGGYSGSVKNRPTR 616

Query: 80  HDGSCGGCSLRAFLIDLHKRL 100
           HD     C     LI  H+ L
Sbjct: 617 HDVLDDSCDGFKDLIKPHEEL 637


>gi|74027251 tripartite motif-containing 33 protein isoform beta
          [Homo sapiens]
          Length = 1110

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 1/59 (1%)

Query: 30 GEGLHTKTALSSRRGKAAAEENPVGLAVLDEEKEGVVGAEAGDESGTPHHHDGSCGGCS 88
          G G  +    +   G AA E  P   AVL EE+E   G  AG E G     DG     S
Sbjct: 14 GGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEE-GGRAGAEGGAAGPDDGGVAAAS 71


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
          [Homo sapiens]
          Length = 1127

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 1/59 (1%)

Query: 30 GEGLHTKTALSSRRGKAAAEENPVGLAVLDEEKEGVVGAEAGDESGTPHHHDGSCGGCS 88
          G G  +    +   G AA E  P   AVL EE+E   G  AG E G     DG     S
Sbjct: 14 GGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEE-GGRAGAEGGAAGPDDGGVAAAS 71


>gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]
          Length = 1537

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 10/59 (16%)

Query: 26   RGQRGEGLHTKTALSSRRGKAAAEENPV-------GLAVLDEEKEGVVGAEAGDESGTP 77
            +G    GL +  +  S+RGK  ++ NP        GLA L  + EG  G EAG E G P
Sbjct: 1340 KGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGL--KGEGSRGKEAG-EGGLP 1395


>gi|6912372 forkhead box D3 [Homo sapiens]
          Length = 478

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 17/43 (39%), Positives = 17/43 (39%)

Query: 44  GKAAAEENPVGLAVLDEEKEGVVGAEAGDESGTPHHHDGSCGG 86
           G  A     VG    D  K GV G E G   G P    GS GG
Sbjct: 87  GAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSGSAGG 129


>gi|7706515 photoreceptor-specific nuclear receptor isoform a [Homo
           sapiens]
          Length = 367

 Score = 27.3 bits (59), Expect = 4.3
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 10/109 (9%)

Query: 35  TKTALSSRRGKAAAEENPVGLAVLDEEKEGVVGA----EAGDESGTPHHHDGSCGGCSLR 90
           T  A +   G A+ +E+P G   L E+  GV  +      GD S   H+   +C GCS  
Sbjct: 12  TVAAAAPAAGAASRKESP-GRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCS-G 69

Query: 91  AFLIDLHKRLVH----DLGQRQVCLGHSREVCLAQLEGISHAQVAQDTL 135
            F   + +RL++      G   V   H  +    +L+    A + QD +
Sbjct: 70  FFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAV 118


>gi|7657395 photoreceptor-specific nuclear receptor isoform b [Homo
           sapiens]
          Length = 410

 Score = 27.3 bits (59), Expect = 4.3
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 10/109 (9%)

Query: 35  TKTALSSRRGKAAAEENPVGLAVLDEEKEGVVGA----EAGDESGTPHHHDGSCGGCSLR 90
           T  A +   G A+ +E+P G   L E+  GV  +      GD S   H+   +C GCS  
Sbjct: 12  TVAAAAPAAGAASRKESP-GRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCS-G 69

Query: 91  AFLIDLHKRLVH----DLGQRQVCLGHSREVCLAQLEGISHAQVAQDTL 135
            F   + +RL++      G   V   H  +    +L+    A + QD +
Sbjct: 70  FFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAV 118


>gi|60685227 SECIS binding protein 2-like [Homo sapiens]
          Length = 1056

 Score = 27.3 bits (59), Expect = 4.3
 Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 3/71 (4%)

Query: 19  AGTLWSVRGQRGEGLHTKTALSSRRGKAAAE-ENPVG-LAVLDEEKEGVVGAEAGDESGT 76
           A  LW  +G+R    H     SS +G + A+ ++  G  +      +   GA    +SGT
Sbjct: 237 ATMLWKSKGRRRRASHPTAESSSEQGASEADIDSDSGYCSPKHSNNQPAAGALRNPDSGT 296

Query: 77  PHHHDGS-CGG 86
            +H + S C G
Sbjct: 297 MNHVESSMCAG 307


>gi|222446611 R-spondin family, member 2 [Homo sapiens]
          Length = 243

 Score = 26.9 bits (58), Expect = 5.6
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 2/39 (5%)

Query: 49  EENPVGLAVLDEEKEGVVGAEAG--DESGTPHHHDGSCG 85
           +E P G A L+E  E V G E G   E GT   ++ +CG
Sbjct: 126 DECPDGFAPLEETMECVEGCEVGHWSEWGTCSRNNRTCG 164


>gi|42794265 MAS-related GPR, member D [Homo sapiens]
          Length = 321

 Score = 26.9 bits (58), Expect = 5.6
 Identities = 8/23 (34%), Positives = 13/23 (56%)

Query: 3   PLFLNCHHCTDKATWVAGTLWSV 25
           P++  CH     + WV G LW++
Sbjct: 130 PIWFKCHRPRHLSAWVCGLLWTL 152


>gi|239753832 PREDICTED: hypothetical protein XP_002345793 [Homo
           sapiens]
          Length = 203

 Score = 26.6 bits (57), Expect = 7.3
 Identities = 19/60 (31%), Positives = 24/60 (40%), Gaps = 8/60 (13%)

Query: 26  RGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDEEKEGVVGAEAGDESGTPHHHDGSCG 85
           +G RG G         RRG    EEN +G+A  D     +V    G    T HH +   G
Sbjct: 50  QGARGAG--------KRRGCELTEENVLGVAAPDLVVAVLVDEGGGARGVTRHHVEAGLG 101


>gi|239748395 PREDICTED: hypothetical protein XP_002346654 [Homo
           sapiens]
          Length = 203

 Score = 26.6 bits (57), Expect = 7.3
 Identities = 19/60 (31%), Positives = 24/60 (40%), Gaps = 8/60 (13%)

Query: 26  RGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDEEKEGVVGAEAGDESGTPHHHDGSCG 85
           +G RG G         RRG    EEN +G+A  D     +V    G    T HH +   G
Sbjct: 50  QGARGAG--------KRRGCELTEENVLGVAAPDLVVAVLVDEGGGARGVTRHHVEAGLG 101


>gi|239742323 PREDICTED: hypothetical protein XP_002342491 [Homo
           sapiens]
          Length = 203

 Score = 26.6 bits (57), Expect = 7.3
 Identities = 19/60 (31%), Positives = 24/60 (40%), Gaps = 8/60 (13%)

Query: 26  RGQRGEGLHTKTALSSRRGKAAAEENPVGLAVLDEEKEGVVGAEAGDESGTPHHHDGSCG 85
           +G RG G         RRG    EEN +G+A  D     +V    G    T HH +   G
Sbjct: 50  QGARGAG--------KRRGCELTEENVLGVAAPDLVVAVLVDEGGGARGVTRHHVEAGLG 101


>gi|150378528 G protein-coupled receptor associated sorting protein
           1 [Homo sapiens]
          Length = 1395

 Score = 26.2 bits (56), Expect = 9.5
 Identities = 14/34 (41%), Positives = 17/34 (50%)

Query: 58  LDEEKEGVVGAEAGDESGTPHHHDGSCGGCSLRA 91
           L  EKEG+VG+  G    T     GSC   S +A
Sbjct: 803 LAAEKEGIVGSWFGAREETIRREAGSCSKSSPKA 836


>gi|150378489 G protein-coupled receptor associated sorting protein
           1 [Homo sapiens]
          Length = 1395

 Score = 26.2 bits (56), Expect = 9.5
 Identities = 14/34 (41%), Positives = 17/34 (50%)

Query: 58  LDEEKEGVVGAEAGDESGTPHHHDGSCGGCSLRA 91
           L  EKEG+VG+  G    T     GSC   S +A
Sbjct: 803 LAAEKEGIVGSWFGAREETIRREAGSCSKSSPKA 836


>gi|103472136 G protein-coupled receptor associated sorting protein
           1 [Homo sapiens]
          Length = 1395

 Score = 26.2 bits (56), Expect = 9.5
 Identities = 14/34 (41%), Positives = 17/34 (50%)

Query: 58  LDEEKEGVVGAEAGDESGTPHHHDGSCGGCSLRA 91
           L  EKEG+VG+  G    T     GSC   S +A
Sbjct: 803 LAAEKEGIVGSWFGAREETIRREAGSCSKSSPKA 836


>gi|10863935 reticulon 1 isoform A [Homo sapiens]
          Length = 776

 Score = 26.2 bits (56), Expect = 9.5
 Identities = 16/55 (29%), Positives = 21/55 (38%)

Query: 30  GEGLHTKTALSSRRGKAAAEENPVGLAVLDEEKEGVVGAEAGDESGTPHHHDGSC 84
           G G   + A S   G   A ++PV +        GV  A     S T    +GSC
Sbjct: 50  GLGARAREAASREAGSGPARQSPVAMETASTGVAGVSSAMDHTFSTTSKDGEGSC 104


>gi|6912676 SKI-interacting protein [Homo sapiens]
          Length = 536

 Score = 26.2 bits (56), Expect = 9.5
 Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 2/43 (4%)

Query: 42  RRGKAAAEENPVGLAVLDEEKEGVVGAEAGDESGTP--HHHDG 82
           R G    EE+P GL    EE +   G++   +S  P  H H+G
Sbjct: 488 REGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEG 530


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,904,552
Number of Sequences: 37866
Number of extensions: 263135
Number of successful extensions: 747
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 731
Number of HSP's gapped (non-prelim): 29
length of query: 141
length of database: 18,247,518
effective HSP length: 92
effective length of query: 49
effective length of database: 14,763,846
effective search space: 723428454
effective search space used: 723428454
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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