Guide to the Human Genome
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Search of human proteins with 239753643

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753643 PREDICTED: similar to Putative uncharacterized
protein C3orf46 [Homo sapiens]
         (149 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753643 PREDICTED: similar to Putative uncharacterized prot...   303   4e-83
gi|27477134 nucleoporin 210 [Homo sapiens]                            148   1e-36
gi|226958663 nucleoporin 210kDa-like isoform 2 [Homo sapiens]          84   3e-17
gi|117414168 nucleoporin 210kDa-like isoform 1 [Homo sapiens]          84   3e-17
gi|210032580 SET domain containing 1B [Homo sapiens]                   32   0.26 
gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]         29   1.7  
gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]         29   1.7  
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...    28   2.2  
gi|50428935 BPY2 interacting protein 1 [Homo sapiens]                  28   2.9  
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 28   3.7  
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 28   3.7  
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  28   3.7  
gi|57863314 vacuolar protein sorting 37C [Homo sapiens]                27   4.9  
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           27   4.9  
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    27   6.4  
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...    27   6.4  
gi|122937289 kinesin family member 18B [Homo sapiens]                  27   8.3  

>gi|239753643 PREDICTED: similar to Putative uncharacterized protein
           C3orf46 [Homo sapiens]
          Length = 149

 Score =  303 bits (776), Expect = 4e-83
 Identities = 149/149 (100%), Positives = 149/149 (100%)

Query: 1   MGKGTVSGLVQVVDAETGKVVIISQDLVQVKVLLLGAVRIRSPIMQIRMGTQLGKNWIHL 60
           MGKGTVSGLVQVVDAETGKVVIISQDLVQVKVLLLGAVRIRSPIMQIRMGTQLGKNWIHL
Sbjct: 1   MGKGTVSGLVQVVDAETGKVVIISQDLVQVKVLLLGAVRIRSPIMQIRMGTQLGKNWIHL 60

Query: 61  PLLEGGSTASGGIPSAGTPLVTRPDFSPPMSIYITWITNHQNPFSFGNAMPGLTFHWSVT 120
           PLLEGGSTASGGIPSAGTPLVTRPDFSPPMSIYITWITNHQNPFSFGNAMPGLTFHWSVT
Sbjct: 61  PLLEGGSTASGGIPSAGTPLVTRPDFSPPMSIYITWITNHQNPFSFGNAMPGLTFHWSVT 120

Query: 121 KRDILDLQGQHHKSSSEACGAGAAGAAAC 149
           KRDILDLQGQHHKSSSEACGAGAAGAAAC
Sbjct: 121 KRDILDLQGQHHKSSSEACGAGAAGAAAC 149


>gi|27477134 nucleoporin 210 [Homo sapiens]
          Length = 1887

 Score =  148 bits (374), Expect = 1e-36
 Identities = 80/135 (59%), Positives = 92/135 (68%), Gaps = 37/135 (27%)

Query: 1    MGKGTVSGLVQVVDAETGKVVIISQDLVQVKVLLLGAVRIRSPIMQIRMGTQLGKNWIHL 60
            +G GTVSGLVQ VDAETGKVVIISQDLVQV+VLLL AVRIR+PIM++R GTQ        
Sbjct: 1133 IGNGTVSGLVQAVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQ-------- 1184

Query: 61   PLLEGGSTASGGIPSAGTPLVTRPDFSPPMSIYITWITNHQNPFSFGNAMPGLTFHWSVT 120
                                         M IY+T ITNHQNPFSFGNA+PGLTFHWSVT
Sbjct: 1185 -----------------------------MPIYVTGITNHQNPFSFGNAVPGLTFHWSVT 1215

Query: 121  KRDILDLQGQHHKSS 135
            KRD+LDL+G+HH++S
Sbjct: 1216 KRDVLDLRGRHHEAS 1230


>gi|226958663 nucleoporin 210kDa-like isoform 2 [Homo sapiens]
          Length = 1736

 Score = 84.3 bits (207), Expect = 3e-17
 Identities = 49/131 (37%), Positives = 69/131 (52%), Gaps = 37/131 (28%)

Query: 1    MGKGTVSGLVQVVDAETGKVVIISQDLVQVKVLLLGAVRIRSPIMQIRMGTQLGKNWIHL 60
            +G   V G +Q V+ +TGKV++ SQD VQ++V+ L AVRI +                  
Sbjct: 1137 VGTAVVHGTIQTVNEDTGKVIVFSQDEVQIEVVQLRAVRILA------------------ 1178

Query: 61   PLLEGGSTASGGIPSAGTPLVTRPDFSPPMSIYITWITNHQNPFSFGNAMPGLTFHWSVT 120
                           A T L+T    +  M +Y+  +T+ Q PFSF NA PGLTFHWS++
Sbjct: 1179 ---------------AATRLIT----ATKMPVYVMGVTSTQTPFSFSNANPGLTFHWSMS 1219

Query: 121  KRDILDLQGQH 131
            KRD+LDL  +H
Sbjct: 1220 KRDVLDLVPRH 1230


>gi|117414168 nucleoporin 210kDa-like isoform 1 [Homo sapiens]
          Length = 1888

 Score = 84.3 bits (207), Expect = 3e-17
 Identities = 49/131 (37%), Positives = 69/131 (52%), Gaps = 37/131 (28%)

Query: 1    MGKGTVSGLVQVVDAETGKVVIISQDLVQVKVLLLGAVRIRSPIMQIRMGTQLGKNWIHL 60
            +G   V G +Q V+ +TGKV++ SQD VQ++V+ L AVRI +                  
Sbjct: 1137 VGTAVVHGTIQTVNEDTGKVIVFSQDEVQIEVVQLRAVRILA------------------ 1178

Query: 61   PLLEGGSTASGGIPSAGTPLVTRPDFSPPMSIYITWITNHQNPFSFGNAMPGLTFHWSVT 120
                           A T L+T    +  M +Y+  +T+ Q PFSF NA PGLTFHWS++
Sbjct: 1179 ---------------AATRLIT----ATKMPVYVMGVTSTQTPFSFSNANPGLTFHWSMS 1219

Query: 121  KRDILDLQGQH 131
            KRD+LDL  +H
Sbjct: 1220 KRDVLDLVPRH 1230


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 31.6 bits (70), Expect = 0.26
 Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 10/83 (12%)

Query: 43  PIMQIRMGTQLGKNWIHLPL--------LEGGSTASGGIPSAGTPLVTRPDFSPPMSIYI 94
           P+MQ+ M   LG  W  +P+        L    T  G  P    P +     +    +  
Sbjct: 754 PVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYP--PFMAAAAAAASAGLQF 811

Query: 95  TWITNHQNPFSFGNAMPGLTFHW 117
             +  ++ PFS  N+ PG   HW
Sbjct: 812 VNLPPYRGPFSLSNSGPGRGQHW 834


>gi|21493039 A-kinase anchor protein 4 isoform 2 [Homo sapiens]
          Length = 845

 Score = 28.9 bits (63), Expect = 1.7
 Identities = 15/53 (28%), Positives = 29/53 (54%), Gaps = 2/53 (3%)

Query: 87  SPPMSIYITWITNHQNPFSFGNAMPGLTFHWSVTKRDILDLQGQHHKSSSEAC 139
           S P+S+ + W+ +    ++ G     L+   S  K  + D +G++H++SSE C
Sbjct: 96  SDPVSV-LNWLLSDLQKYALG-FQHALSPSTSTCKHKVGDTEGEYHRASSENC 146


>gi|21493037 A-kinase anchor protein 4 isoform 1 [Homo sapiens]
          Length = 854

 Score = 28.9 bits (63), Expect = 1.7
 Identities = 15/53 (28%), Positives = 29/53 (54%), Gaps = 2/53 (3%)

Query: 87  SPPMSIYITWITNHQNPFSFGNAMPGLTFHWSVTKRDILDLQGQHHKSSSEAC 139
           S P+S+ + W+ +    ++ G     L+   S  K  + D +G++H++SSE C
Sbjct: 105 SDPVSV-LNWLLSDLQKYALG-FQHALSPSTSTCKHKVGDTEGEYHRASSENC 155


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score = 28.5 bits (62), Expect = 2.2
 Identities = 13/36 (36%), Positives = 21/36 (58%), Gaps = 1/36 (2%)

Query: 55  KNWIHLPLLEGGSTASGGIPSAGTPLVTRP-DFSPP 89
           ++W+  PL  GG+TA   +P  G P  + P  ++PP
Sbjct: 242 ESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPP 277


>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
          Length = 1059

 Score = 28.1 bits (61), Expect = 2.9
 Identities = 19/78 (24%), Positives = 29/78 (37%)

Query: 7   SGLVQVVDAETGKVVIISQDLVQVKVLLLGAVRIRSPIMQIRMGTQLGKNWIHLPLLEGG 66
           S LV     E G +    +  +++ +      R R+P  +       G   + L  L GG
Sbjct: 603 SQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGG 662

Query: 67  STASGGIPSAGTPLVTRP 84
                  P+  TP VT P
Sbjct: 663 EAGPDASPTVTTPTVTTP 680


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 8/66 (12%)

Query: 31   KVLLLGAVRIRSPIM-QIRMGTQL-------GKNWIHLPLLEGGSTASGGIPSAGTPLVT 82
            K L+ G VR  S I  Q++   Q        G+  IH+P +   S+++  +   G PL T
Sbjct: 2196 KSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKT 2255

Query: 83   RPDFSP 88
                SP
Sbjct: 2256 PASKSP 2261


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 8/66 (12%)

Query: 31   KVLLLGAVRIRSPIM-QIRMGTQL-------GKNWIHLPLLEGGSTASGGIPSAGTPLVT 82
            K L+ G VR  S I  Q++   Q        G+  IH+P +   S+++  +   G PL T
Sbjct: 2196 KSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKT 2255

Query: 83   RPDFSP 88
                SP
Sbjct: 2256 PASKSP 2261


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 8/66 (12%)

Query: 31   KVLLLGAVRIRSPIM-QIRMGTQL-------GKNWIHLPLLEGGSTASGGIPSAGTPLVT 82
            K L+ G VR  S I  Q++   Q        G+  IH+P +   S+++  +   G PL T
Sbjct: 2196 KSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKT 2255

Query: 83   RPDFSP 88
                SP
Sbjct: 2256 PASKSP 2261


>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
          Length = 355

 Score = 27.3 bits (59), Expect = 4.9
 Identities = 12/26 (46%), Positives = 16/26 (61%)

Query: 61  PLLEGGSTASGGIPSAGTPLVTRPDF 86
           P L  G TA G +P A  P+V++P F
Sbjct: 211 PSLPVGPTAHGALPPAPFPVVSQPSF 236


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 27.3 bits (59), Expect = 4.9
 Identities = 15/46 (32%), Positives = 21/46 (45%)

Query: 102  NPFSFGNAMPGLTFHWSVTKRDILDLQGQHHKSSSEACGAGAAGAA 147
            +P + G   PG      + K D+    G H + SS   G+  AGAA
Sbjct: 1106 DPLALGPESPGEPQPPQLKKDDVTSSTGPHKELSSTEAGSTVAGAA 1151


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 26.9 bits (58), Expect = 6.4
 Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 17/95 (17%)

Query: 28  VQVKVLLLGAVRIRSPIMQIRMGTQLGKNWIHLPLLEGGSTASGGIPSAG-TPLVTRPDF 86
           VQV   +    R RSP    R    + K     PL +   ++  G PSA  TP  T  DF
Sbjct: 725 VQVYFYVSNGRRKRSPTQSFRFLPVICKEE---PLPD---SSLRGFPSASATPFGTDMDF 778

Query: 87  SPPMSIYITWITNHQNPF--------SFGNAMPGL 113
           SPP   Y ++   H++P          FG  MP L
Sbjct: 779 SPPRPPYPSY--PHEDPACETPYLSEGFGYGMPPL 811


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score = 26.9 bits (58), Expect = 6.4
 Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 17/95 (17%)

Query: 28  VQVKVLLLGAVRIRSPIMQIRMGTQLGKNWIHLPLLEGGSTASGGIPSAG-TPLVTRPDF 86
           VQV   +    R RSP    R    + K     PL +   ++  G PSA  TP  T  DF
Sbjct: 662 VQVYFYVSNGRRKRSPTQSFRFLPVICKEE---PLPD---SSLRGFPSASATPFGTDMDF 715

Query: 87  SPPMSIYITWITNHQNPF--------SFGNAMPGL 113
           SPP   Y ++   H++P          FG  MP L
Sbjct: 716 SPPRPPYPSY--PHEDPACETPYLSEGFGYGMPPL 748


>gi|122937289 kinesin family member 18B [Homo sapiens]
          Length = 855

 Score = 26.6 bits (57), Expect = 8.3
 Identities = 13/31 (41%), Positives = 17/31 (54%)

Query: 110 MPGLTFHWSVTKRDILDLQGQHHKSSSEACG 140
           +PGLT    V K  ++DL G    SS+ A G
Sbjct: 238 VPGLTQAVQVAKMSLIDLAGSERASSTHAKG 268


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,746,112
Number of Sequences: 37866
Number of extensions: 253781
Number of successful extensions: 723
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 708
Number of HSP's gapped (non-prelim): 18
length of query: 149
length of database: 18,247,518
effective HSP length: 93
effective length of query: 56
effective length of database: 14,725,980
effective search space: 824654880
effective search space used: 824654880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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