Guide to the Human Genome
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Search of human proteins with 239752017

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239752017 PREDICTED: hypothetical protein XP_002348069 [Homo
sapiens]
         (363 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239752017 PREDICTED: hypothetical protein XP_002348069 [Homo ...   780   0.0  
gi|239757500 PREDICTED: hypothetical protein [Homo sapiens]           637   0.0  
gi|145309328 papilin [Homo sapiens]                                    33   0.40 
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        31   2.0  
gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]    30   3.4  
gi|56788370 pleckstrin and Sec7 domain containing 4 [Homo sapiens]     30   3.4  
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]      29   7.5  
gi|169212963 PREDICTED: hypothetical protein [Homo sapiens]            29   7.5  
gi|169213148 PREDICTED: hypothetical protein [Homo sapiens]            29   7.5  
gi|169212812 PREDICTED: hypothetical protein [Homo sapiens]            29   7.5  
gi|195927059 axin 2 [Homo sapiens]                                     29   7.5  
gi|47551356 hypothetical protein LOC408029 [Homo sapiens]              28   9.8  
gi|47524184 hypothetical protein LOC29798 [Homo sapiens]               28   9.8  
gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens]     28   9.8  
gi|197304775 TBC1 domain family, member 5 isoform b [Homo sapiens]     28   9.8  
gi|7661998 TBC1 domain family, member 5 isoform b [Homo sapiens]       28   9.8  
gi|190014607 netrin G2 [Homo sapiens]                                  28   9.8  

>gi|239752017 PREDICTED: hypothetical protein XP_002348069 [Homo
           sapiens]
          Length = 363

 Score =  780 bits (2015), Expect = 0.0
 Identities = 363/363 (100%), Positives = 363/363 (100%)

Query: 1   MELSSFCALPCHLPERNGSCSCWKGQESEWGDTSGAPDKVGQPLGQATCAGLLDVEGSGE 60
           MELSSFCALPCHLPERNGSCSCWKGQESEWGDTSGAPDKVGQPLGQATCAGLLDVEGSGE
Sbjct: 1   MELSSFCALPCHLPERNGSCSCWKGQESEWGDTSGAPDKVGQPLGQATCAGLLDVEGSGE 60

Query: 61  EIVEGAVAHGHHSAREADHVVGHAEVRCRQVHQQRLRVEPHKVVRAIRDWEPGAVEEGTL 120
           EIVEGAVAHGHHSAREADHVVGHAEVRCRQVHQQRLRVEPHKVVRAIRDWEPGAVEEGTL
Sbjct: 61  EIVEGAVAHGHHSAREADHVVGHAEVRCRQVHQQRLRVEPHKVVRAIRDWEPGAVEEGTL 120

Query: 121 FPVHWLGCYHAGHKGAEDRWATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYGVQQQHR 180
           FPVHWLGCYHAGHKGAEDRWATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYGVQQQHR
Sbjct: 121 FPVHWLGCYHAGHKGAEDRWATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYGVQQQHR 180

Query: 181 EGPVWVGVVQQCAQLPLLQPIATHVPLGMQEGHWGGLCVKKYQQLTAAKGPKVCTHSVTV 240
           EGPVWVGVVQQCAQLPLLQPIATHVPLGMQEGHWGGLCVKKYQQLTAAKGPKVCTHSVTV
Sbjct: 181 EGPVWVGVVQQCAQLPLLQPIATHVPLGMQEGHWGGLCVKKYQQLTAAKGPKVCTHSVTV 240

Query: 241 SWNQTHSSAPDGACRKGGPQYRVLQKPCVNDRSRALTSFPLKLRIPARAELECGGYVPGR 300
           SWNQTHSSAPDGACRKGGPQYRVLQKPCVNDRSRALTSFPLKLRIPARAELECGGYVPGR
Sbjct: 241 SWNQTHSSAPDGACRKGGPQYRVLQKPCVNDRSRALTSFPLKLRIPARAELECGGYVPGR 300

Query: 301 QRGDDKFLPQAVAWGFCKAPAAGPQEQQDEQSKRHSRRHACGYFRLPSGARPHEKPVSNK 360
           QRGDDKFLPQAVAWGFCKAPAAGPQEQQDEQSKRHSRRHACGYFRLPSGARPHEKPVSNK
Sbjct: 301 QRGDDKFLPQAVAWGFCKAPAAGPQEQQDEQSKRHSRRHACGYFRLPSGARPHEKPVSNK 360

Query: 361 KGV 363
           KGV
Sbjct: 361 KGV 363


>gi|239757500 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 407

 Score =  637 bits (1643), Expect = 0.0
 Identities = 315/387 (81%), Positives = 320/387 (82%), Gaps = 42/387 (10%)

Query: 15  ERNGSCSCWKGQESEWGDTSGAPDKVGQPLGQATCAGLLDVEGSGEEIVEGAVAHGHHSA 74
           ERNGSCSCWKGQESEWGDTSGAPDKVGQPLGQATCAGLLDVEGSGEEIVEGAVAHGHHSA
Sbjct: 25  ERNGSCSCWKGQESEWGDTSGAPDKVGQPLGQATCAGLLDVEGSGEEIVEGAVAHGHHSA 84

Query: 75  READHVVGHAEVRCRQVHQQRLRVEPHKVVRAIRDWEPGAVEEGTLFPVHWLGCYHAGHK 134
           READHVVGHAEVRCRQVHQQRLRVEPHKVVRAIRDWEPGAVEEGTLFPVHWLGCYHAGHK
Sbjct: 85  READHVVGHAEVRCRQVHQQRLRVEPHKVVRAIRDWEPGAVEEGTLFPVHWLGCYHAGHK 144

Query: 135 GAEDRWATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYGVQQQHREGPVWVGVVQQCAQ 194
           GAEDRWATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYGVQQQHREGPVWVGVVQQCAQ
Sbjct: 145 GAEDRWATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYGVQQQHREGPVWVGVVQQCAQ 204

Query: 195 LPLLQPIATHVPLGMQEGHWGGLCVKKYQQLTAAKGPKVCTHSVTVSWNQTHSSAPDGAC 254
           LPLLQPIATHVPLGMQEGHWGGLCVKKYQQLTAAKG       V  +W        + AC
Sbjct: 205 LPLLQPIATHVPLGMQEGHWGGLCVKKYQQLTAAKG----AAPVENTWRSAAPGLWERAC 260

Query: 255 RKG-GPQYRVLQKPCVND-------------------------------------RSRAL 276
               G + +V   P +                                       RSRAL
Sbjct: 261 NGTLGKREQVSDDPHLVGVHTQDPELYPGIRPRPQSLPSSHGRPASRHYGNLSLVRSRAL 320

Query: 277 TSFPLKLRIPARAELECGGYVPGRQRGDDKFLPQAVAWGFCKAPAAGPQEQQDEQSKRHS 336
           TSFPLKLRIPARAELECGGYVPGRQRGDDKFLPQAVAWGFCKAPAAGPQEQQDEQSKRHS
Sbjct: 321 TSFPLKLRIPARAELECGGYVPGRQRGDDKFLPQAVAWGFCKAPAAGPQEQQDEQSKRHS 380

Query: 337 RRHACGYFRLPSGARPHEKPVSNKKGV 363
           RRHACGYFRLPSGARPHEKPVSNKKGV
Sbjct: 381 RRHACGYFRLPSGARPHEKPVSNKKGV 407


>gi|145309328 papilin [Homo sapiens]
          Length = 1251

 Score = 33.1 bits (74), Expect = 0.40
 Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 22/137 (16%)

Query: 222 YQQ-LTAAKGPKVCTHSVTVSWNQTHSSAPDGACRKGGPQYRVLQ-KPCVNDRSRALTSF 279
           YQQ L +  GP  C HS        H   PDG     GPQ++     PC   R       
Sbjct: 590 YQQPLRSGSGPHDCRHS-------PHGCCPDGHTASLGPQWQGCPGAPCQQSRYGCC--- 639

Query: 280 PLKLRIPARAELECGGYVPG--RQRGDDKF--LPQAVAWGFCKAPAAGPQEQQDEQSKRH 335
                 P R  +  G +  G  +  G D    +P++ A          PQ QQ+E S+  
Sbjct: 640 ------PDRVSVAEGPHHAGCTKSYGGDSTGGMPRSRAVASTVHNTHQPQAQQNEPSECR 693

Query: 336 SRRHACGYFRLPSGARP 352
             +  C Y  + + A P
Sbjct: 694 GSQFGCCYDNVATAAGP 710


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 16/38 (42%), Positives = 20/38 (52%)

Query: 319  APAAGPQEQQDEQSKRHSRRHACGYFRLPSGARPHEKP 356
            +P   P++QQ   S+R SRR   G  R PS  R  E P
Sbjct: 2702 SPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETP 2739


>gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]
          Length = 2608

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 36/117 (30%), Positives = 45/117 (38%), Gaps = 18/117 (15%)

Query: 251 DGACRKGGPQYRVLQKPCVNDRSRALTSFPLKLRI----PARAEL-ECGGYVPGRQRGDD 305
           DG CR+GGP  R         R + LTS  L  ++      RA L  C G + GR     
Sbjct: 259 DGHCREGGPAPR----GACEGRPKHLTSCLLNTKVLNGEMGRAALASCAGGMLGRPG--- 311

Query: 306 KFLPQAVAWGFCKAPAAGPQEQQDEQSKRHSRRHACGYFRLPSGARPHEKPVSNKKG 362
                 V  G C   AAGP E     S+   RR    +    +G  P   P+S   G
Sbjct: 312 ---TGVVTSGRCAKEAAGPPEPGPAFSECLERRQMLHHTASYAGPPP---PLSTAAG 362


>gi|56788370 pleckstrin and Sec7 domain containing 4 [Homo sapiens]
          Length = 1056

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 5/68 (7%)

Query: 6   FCALPCHLPERNGSCSCWKGQESEWGDTSG--APDKVGQPLGQATCAGLLDVEGSGEEIV 63
           F A PC     +G C  W   +S  G  +G  +P  +  PL + T    L+ E    ++ 
Sbjct: 251 FLASPCSENSASGECFSWGASDSHAGVRTGPESPATLEPPLPEDTVLWELESE---PDLG 307

Query: 64  EGAVAHGH 71
           +GA   GH
Sbjct: 308 DGAAISGH 315


>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
          Length = 4753

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 8/90 (8%)

Query: 132  GHKGAEDRWATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYGVQQQHREGPVWVGVVQQ 191
            G K  +D W +          LA L  G GE V +Q  +P       H + P W+  +++
Sbjct: 1402 GEKNTDD-WESSPNTQTQVEALAVLGAG-GEEVKLQGPLP------LHPDLPKWLASLEK 1453

Query: 192  CAQLPLLQPIATHVPLGMQEGHWGGLCVKK 221
            C +L L+  +   V   +  G   G  +K+
Sbjct: 1454 CLRLALVHMLQGCVAARLARGPSLGEALKQ 1483


>gi|169212963 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 134

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 4/35 (11%)

Query: 140 WATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYG 174
           W T  QR+GP SH    S G      + P +PG G
Sbjct: 19  WKTHVQREGPRSH----SLGTSSAFWLSPPLPGEG 49


>gi|169213148 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 134

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 4/35 (11%)

Query: 140 WATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYG 174
           W T  QR+GP SH    S G      + P +PG G
Sbjct: 19  WKTHVQREGPRSH----SLGTSSAFWLSPPLPGEG 49


>gi|169212812 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 134

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 4/35 (11%)

Query: 140 WATEKQRDGPCSHLAALSRGDGEGVHIQPQIPGYG 174
           W T  QR+GP SH    S G      + P +PG G
Sbjct: 19  WKTHVQREGPRSH----SLGTSSAFWLSPPLPGEG 49


>gi|195927059 axin 2 [Homo sapiens]
          Length = 843

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 21/83 (25%), Positives = 30/83 (36%), Gaps = 7/83 (8%)

Query: 269 VNDRSRALTSFPLKLRIPARAELECGGYVPGRQRGDDKFLPQAVAWGFCKAPAAGPQEQQ 328
           +N R  A T  PL L       L  G Y    Q   D  L + +    C++P  G    +
Sbjct: 411 LNSREGAPTQHPLSL-------LPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPR 463

Query: 329 DEQSKRHSRRHACGYFRLPSGAR 351
                 H   H+  +  LP G +
Sbjct: 464 SRSPDHHHHHHSQYHSLLPPGGK 486


>gi|47551356 hypothetical protein LOC408029 [Homo sapiens]
          Length = 209

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 16/39 (41%), Positives = 18/39 (46%)

Query: 309 PQAVAWGFCKAPAAGPQEQQDEQSKRHSRRHACGYFRLP 347
           P A A G    PA G  EQ+ E   R S R +C   R P
Sbjct: 154 PAATAAGAVCLPAGGAGEQEKEPVSRGSSRSSCSQRRPP 192


>gi|47524184 hypothetical protein LOC29798 [Homo sapiens]
          Length = 203

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 16/39 (41%), Positives = 18/39 (46%)

Query: 309 PQAVAWGFCKAPAAGPQEQQDEQSKRHSRRHACGYFRLP 347
           P A A G    PA G  EQ+ E   R S R +C   R P
Sbjct: 148 PAATAAGAVCLPAGGAGEQEKEPVSRGSSRSSCSQRRPP 186


>gi|197304777 TBC1 domain family, member 5 isoform a [Homo sapiens]
          Length = 817

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 5/65 (7%)

Query: 269 VNDRSRALTSFPLKLRIPARAELECGGYVPGRQRGDDK--FLPQAVAWGFCKAPAAGPQE 326
           +N  S +L +F  KL  PA A    GG VPG          +P   +    +AP+   Q+
Sbjct: 454 INKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTS---AEAPSHHLQQ 510

Query: 327 QQDEQ 331
           QQ +Q
Sbjct: 511 QQQQQ 515


>gi|197304775 TBC1 domain family, member 5 isoform b [Homo sapiens]
          Length = 795

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 5/65 (7%)

Query: 269 VNDRSRALTSFPLKLRIPARAELECGGYVPGRQRGDDK--FLPQAVAWGFCKAPAAGPQE 326
           +N  S +L +F  KL  PA A    GG VPG          +P   +    +AP+   Q+
Sbjct: 454 INKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTS---AEAPSHHLQQ 510

Query: 327 QQDEQ 331
           QQ +Q
Sbjct: 511 QQQQQ 515


>gi|7661998 TBC1 domain family, member 5 isoform b [Homo sapiens]
          Length = 795

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 5/65 (7%)

Query: 269 VNDRSRALTSFPLKLRIPARAELECGGYVPGRQRGDDK--FLPQAVAWGFCKAPAAGPQE 326
           +N  S +L +F  KL  PA A    GG VPG          +P   +    +AP+   Q+
Sbjct: 454 INKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTS---AEAPSHHLQQ 510

Query: 327 QQDEQ 331
           QQ +Q
Sbjct: 511 QQQQQ 515


>gi|190014607 netrin G2 [Homo sapiens]
          Length = 530

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 3/76 (3%)

Query: 200 PIATHVPLGMQEGHWGGLCVKKYQQLTAAKGPKVCTHSVTVSWNQTHSSAPDGAC--RKG 257
           P   H P  M +    GL    +Q +T ++ P     ++T+SWN+T     D       G
Sbjct: 86  PDLAHPPRLMFDKEEEGLATY-WQSITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYG 144

Query: 258 GPQYRVLQKPCVNDRS 273
            P   VL+K   N R+
Sbjct: 145 RPTVMVLEKSLDNGRT 160


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,547,847
Number of Sequences: 37866
Number of extensions: 906593
Number of successful extensions: 1961
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1953
Number of HSP's gapped (non-prelim): 20
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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