Guide to the Human Genome
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Search of human proteins with 118582275

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118582275 superoxide dismutase 3, extracellular precursor
[Homo sapiens]
         (240 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118582275 superoxide dismutase 3, extracellular precursor [Ho...   498   e-141
gi|4507149 superoxide dismutase 1, soluble [Homo sapiens]             105   5e-23
gi|4826665 copper chaperone for superoxide dismutase [Homo sapiens]    87   2e-17
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    31   1.1  
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                30   2.4  
gi|118918415 shank-interacting protein-like 1 [Homo sapiens]           30   2.4  
gi|38045906 von Hippel-Lindau tumor suppressor isoform 2 [Homo s...    29   3.2  
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           29   3.2  
gi|169165408 PREDICTED: hypothetical protein [Homo sapiens]            28   7.1  
gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo ...    28   7.1  
gi|169165822 PREDICTED: hypothetical protein [Homo sapiens]            28   7.1  
gi|169165004 PREDICTED: hypothetical protein [Homo sapiens]            28   7.1  
gi|31543535 R3H domain containing 1 [Homo sapiens]                     28   7.1  
gi|94536798 high mobility group AT-hook 1-like 4 [Homo sapiens]        28   7.1  
gi|193804923 hypothetical protein LOC55086 [Homo sapiens]              28   7.1  
gi|239752994 PREDICTED: achaete-scute complex homolog 5 (Drosoph...    28   9.2  
gi|239747548 PREDICTED: achaete-scute complex homolog 5 (Drosoph...    28   9.2  
gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo ...    28   9.2  
gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo sa...    28   9.2  
gi|148612853 ATP-binding cassette, sub-family F (GCN20), member ...    28   9.2  

>gi|118582275 superoxide dismutase 3, extracellular precursor [Homo
           sapiens]
          Length = 240

 Score =  498 bits (1281), Expect = e-141
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALH 60
           MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALH
Sbjct: 1   MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALH 60

Query: 61  AACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGD 120
           AACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGD
Sbjct: 61  AACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGD 120

Query: 121 LSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVV 180
           LSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVV
Sbjct: 121 LSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVV 180

Query: 181 HAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA 240
           HAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA
Sbjct: 181 HAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA 240


>gi|4507149 superoxide dismutase 1, soluble [Homo sapiens]
          Length = 154

 Score =  105 bits (261), Expect = 5e-23
 Identities = 57/142 (40%), Positives = 78/142 (54%), Gaps = 11/142 (7%)

Query: 78  VTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAV 137
           V G++ F Q      +  + +++G            HVH+FGD + GC S GPH+NPL+ 
Sbjct: 15  VQGIINFEQKESNGPVKVWGSIKGL----TEGLHGFHVHEFGDNTAGCTSAGPHFNPLSR 70

Query: 138 PH------PQHPGDFGNF-AVRDGSLWRYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRG 190
            H       +H GD GN  A +DG           SL+G H I+GR +VVH   DDLG+G
Sbjct: 71  KHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKG 130

Query: 191 GNQASVENGNAGRRLACCVVGV 212
           GN+ S + GNAG RLAC V+G+
Sbjct: 131 GNEESTKTGNAGSRLACGVIGI 152


>gi|4826665 copper chaperone for superoxide dismutase [Homo sapiens]
          Length = 274

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 63/178 (35%), Positives = 85/178 (47%), Gaps = 29/178 (16%)

Query: 78  VTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAV 137
           V GVV F QL P   L     +EG           +HVHQ+GDL+  C S G H+NP   
Sbjct: 99  VQGVVRFLQLTPERCL-----IEGTIDGLEPGLHGLHVHQYGDLTNNCNSCGNHFNPDGA 153

Query: 138 PH--PQ----HPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGG 191
            H  PQ    H GD GN  VR  +  R    +         ++GR++++  GEDDLGRGG
Sbjct: 154 SHGGPQDSDRHRGDLGN--VRADADGRAIFRMEDEQLKVWDVIGRSLIIDEGEDDLGRGG 211

Query: 192 NQASVENGNAGRRLACCVVG-----------VC---GPGLWERQAREHSERKKRRRES 235
           +  S   GN+G RLAC ++            +C   G  +WE + R  +   K R+ES
Sbjct: 212 HPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIA--GKGRKES 267


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 16/49 (32%), Positives = 22/49 (44%)

Query: 188 GRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESE 236
           G+  +    E+G  GR    C  G  G   W+ + RE  E+ K R E E
Sbjct: 639 GKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEME 687


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 13/37 (35%), Positives = 17/37 (45%)

Query: 102 FPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVP 138
           FP  P     ++  H F    QG +S  PHY P + P
Sbjct: 564 FPQSPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPP 600


>gi|118918415 shank-interacting protein-like 1 [Homo sapiens]
          Length = 387

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 6/84 (7%)

Query: 60  HAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFG 119
           H A QV P  T+ A Q +V   + F     R  +     +      P  S  +  V Q G
Sbjct: 239 HVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCV------PERSLASYGVRQDG 292

Query: 120 DLSQGCESTGPHYNPLAVPHPQHP 143
           D +     + P   P   P PQHP
Sbjct: 293 DPAFLYLLSAPREAPATGPSPQHP 316


>gi|38045906 von Hippel-Lindau tumor suppressor isoform 2 [Homo
           sapiens]
          Length = 172

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 17/64 (26%), Positives = 28/64 (43%), Gaps = 4/64 (6%)

Query: 66  QPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEG----FPTEPNSSSRAIHVHQFGDL 121
           +P   L +   R    V+F   +PR  L  +   +G    +PT P  + R IH ++   L
Sbjct: 58  RPRPVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRVYTL 117

Query: 122 SQGC 125
            + C
Sbjct: 118 KERC 121


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 5/101 (4%)

Query: 58  ALHAACQVQPSATLDAAQPRVTGV-VLFRQLAPRAKLDAFFALEGFPT--EPNSSSRAIH 114
           +LH A    P  T  A QP VTG+      L   + LD+  A+ G     +P +  +A  
Sbjct: 411 SLHPAHPALPQMTSQAPQPSVTGLQAPSAALMQVSSLDSHSAVSGNAQSFQPYAGMQAYA 470

Query: 115 VHQFGDLSQGCESTGPHY-NPLA-VPHPQHPGDFGNFAVRD 153
             Q   ++   +   P Y  PL+  PH Q  GD  +F + +
Sbjct: 471 YPQASAVTSQLQPVRPLYPAPLSQPPHFQGSGDMASFLMTE 511


>gi|169165408 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 172

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 16/80 (20%)

Query: 89  PRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPQHPGDFGN 148
           P + L+ FF  EG     + +   IH  Q           GP  +PL  P  +HPG  G 
Sbjct: 19  PSSLLETFFFPEG-----DGTVTLIHPGQ-----------GPQTSPLLRPRRRHPGSTGP 62

Query: 149 FAVRDGSLWRYRAGLAASLA 168
                 S W+ RA  A  L+
Sbjct: 63  RDRAAESAWKRRALKAKRLS 82


>gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo
           sapiens]
          Length = 870

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 42/145 (28%), Positives = 55/145 (37%), Gaps = 27/145 (18%)

Query: 73  AAQPRVTGVVLFRQLA-PRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPH 131
           AA+P + G  + R LA   A+L  +      P     S RA + H+  ++  G       
Sbjct: 576 AARPGLAGSGVQRALALAAAQLGGWTTCVVSPNLRRGSRRAGN-HRVREIEFGSAL---- 630

Query: 132 YNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGG 191
              LA  +   PG FG             AGL A   GP S      VV+  E  L    
Sbjct: 631 ---LAALNTLGPGSFG-------------AGLGAQ--GPRSSTPECPVVNGSEWGLAA-- 670

Query: 192 NQASVENGNAGRRLACCVVGVCGPG 216
              S E G+ GR       G+CGPG
Sbjct: 671 -PLSPERGSPGRPAFLRSPGLCGPG 694


>gi|169165822 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 172

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 16/80 (20%)

Query: 89  PRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPQHPGDFGN 148
           P + L+ FF  EG     + +   IH  Q           GP  +PL  P  +HPG  G 
Sbjct: 19  PSSLLETFFFPEG-----DGTVTLIHPGQ-----------GPQTSPLLRPRRRHPGSTGP 62

Query: 149 FAVRDGSLWRYRAGLAASLA 168
                 S W+ RA  A  L+
Sbjct: 63  RDRAAESAWKRRALKAKRLS 82


>gi|169165004 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 172

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 16/80 (20%)

Query: 89  PRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPQHPGDFGN 148
           P + L+ FF  EG     + +   IH  Q           GP  +PL  P  +HPG  G 
Sbjct: 19  PSSLLETFFFPEG-----DGTVTLIHPGQ-----------GPQTSPLLRPRRRHPGSTGP 62

Query: 149 FAVRDGSLWRYRAGLAASLA 168
                 S W+ RA  A  L+
Sbjct: 63  RDRAAESAWKRRALKAKRLS 82


>gi|31543535 R3H domain containing 1 [Homo sapiens]
          Length = 1099

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 2/60 (3%)

Query: 132 YNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAAS--LAGPHSIVGRAVVVHAGEDDLGR 189
           YNP AV H   P   G    R G+  R +A  AAS  L    ++VG+ + +    D + R
Sbjct: 939 YNPPAVLHGHIPNQQGQPGSRHGNRGRRQAKKAASTDLGAGETVVGKVLEITELPDGITR 998


>gi|94536798 high mobility group AT-hook 1-like 4 [Homo sapiens]
          Length = 356

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 11/48 (22%), Positives = 24/48 (50%)

Query: 189 RGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESE 236
           RG    ++E    G  L   + G  G G+ +++ ++H ++ K++   E
Sbjct: 7   RGSTSGAMEAPEPGEALELSLAGAHGHGVHKKKHKKHKKKHKKKHHQE 54


>gi|193804923 hypothetical protein LOC55086 [Homo sapiens]
          Length = 855

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 15/41 (36%), Positives = 20/41 (48%)

Query: 129 GPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAG 169
           GPH NP+AVP P              S++  RA + A+L G
Sbjct: 630 GPHANPVAVPQPGASVQTKGIKPGMPSIFNRRANINANLQG 670


>gi|239752994 PREDICTED: achaete-scute complex homolog 5
           (Drosophila) [Homo sapiens]
          Length = 313

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 12/24 (50%), Positives = 13/24 (54%)

Query: 122 SQGCESTGPHYNPLAVPHPQHPGD 145
           S+G   TGP   P A P P  PGD
Sbjct: 258 SRGLPGTGPCPAPPATPRPDRPGD 281


>gi|239747548 PREDICTED: achaete-scute complex homolog 5
           (Drosophila) [Homo sapiens]
          Length = 313

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 12/24 (50%), Positives = 13/24 (54%)

Query: 122 SQGCESTGPHYNPLAVPHPQHPGD 145
           S+G   TGP   P A P P  PGD
Sbjct: 258 SRGLPGTGPCPAPPATPRPDRPGD 281


>gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo
           sapiens]
          Length = 538

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 27/82 (32%), Positives = 31/82 (37%), Gaps = 18/82 (21%)

Query: 135 LAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQA 194
           LA  +   PG FG             AGL A   GP S      VV+  E  L       
Sbjct: 299 LAALNTLGPGSFG-------------AGLGAQ--GPRSSTPECPVVNGSEWGLAA---PL 340

Query: 195 SVENGNAGRRLACCVVGVCGPG 216
           S E G+ GR       G+CGPG
Sbjct: 341 SPERGSPGRPAFLRSPGLCGPG 362


>gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo
           sapiens]
          Length = 313

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 12/24 (50%), Positives = 13/24 (54%)

Query: 122 SQGCESTGPHYNPLAVPHPQHPGD 145
           S+G   TGP   P A P P  PGD
Sbjct: 258 SRGLPGTGPCPAPPATPRPDRPGD 281


>gi|148612853 ATP-binding cassette, sub-family F (GCN20), member 3
          [Homo sapiens]
          Length = 709

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 33 EWIRDMYAKVTEIWQEVMQRRDDDGALHAACQVQPSATLDAAQPRVTG 80
          E + D+   V E+ QEV     DD  + A CQ +   TL  A+P+  G
Sbjct: 35 ESVDDLVEAVGELLQEVSGDSKDDAGIRAVCQ-RMYNTLRLAEPQSQG 81


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,623,378
Number of Sequences: 37866
Number of extensions: 499480
Number of successful extensions: 1449
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1437
Number of HSP's gapped (non-prelim): 21
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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