BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo sapiens] (1731 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 3498 0.0 gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens] 3491 0.0 gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 3487 0.0 gi|31559825 polycystin 1-like 3 [Homo sapiens] 3486 0.0 gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 536 e-152 gi|5174633 receptor for egg jelly-like protein precursor [Homo s... 182 2e-45 gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 179 2e-44 gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 179 2e-44 gi|19923084 polycystin-1L1 [Homo sapiens] 121 5e-27 gi|4505835 polycystin 2 [Homo sapiens] 84 9e-16 gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 81 8e-15 gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 79 4e-14 gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 79 4e-14 gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] 75 6e-13 gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens] 67 2e-10 gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] 58 7e-08 gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ... 58 7e-08 gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ... 58 7e-08 gi|229093087 G protein-coupled receptor 97 [Homo sapiens] 47 2e-04 gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] 46 3e-04 gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi... 45 5e-04 gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapi... 45 5e-04 gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapi... 45 5e-04 gi|27436974 potassium voltage-gated channel, Shab-related subfam... 44 0.001 gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 44 0.002 gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 44 0.002 gi|4826784 potassium voltage-gated channel, Shab-related subfami... 42 0.004 gi|224809323 G protein-coupled receptor 56 isoform b precursor [... 42 0.004 gi|224809320 G protein-coupled receptor 56 isoform c precursor [... 42 0.004 gi|224809318 G protein-coupled receptor 56 isoform b precursor [... 42 0.004 >gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo sapiens] Length = 1731 Score = 3498 bits (9070), Expect = 0.0 Identities = 1731/1731 (100%), Positives = 1731/1731 (100%) Query: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH Sbjct: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60 Query: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI Sbjct: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120 Query: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP Sbjct: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180 Query: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS Sbjct: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240 Query: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL Sbjct: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300 Query: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS Sbjct: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360 Query: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL Sbjct: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420 Query: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN Sbjct: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480 Query: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS Sbjct: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540 Query: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQ 600 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQ Sbjct: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQ 600 Query: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR Sbjct: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660 Query: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK Sbjct: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720 Query: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC Sbjct: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780 Query: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF Sbjct: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840 Query: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF Sbjct: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900 Query: 901 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI Sbjct: 901 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960 Query: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL Sbjct: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020 Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080 Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140 Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200 Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260 ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAPA Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260 Query: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ Sbjct: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320 Query: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG Sbjct: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380 Query: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR Sbjct: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440 Query: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN Sbjct: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500 Query: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL Sbjct: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560 Query: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR Sbjct: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620 Query: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE Sbjct: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680 Query: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP Sbjct: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731 >gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens] Length = 1731 Score = 3491 bits (9052), Expect = 0.0 Identities = 1727/1731 (99%), Positives = 1729/1731 (99%) Query: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH Sbjct: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60 Query: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI Sbjct: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120 Query: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP Sbjct: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180 Query: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240 GHLPTTCHYPLPAHLSKTLCHPISQFPSVL SITSQVTSAASEPSSQPLPVITQLTMPVS Sbjct: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240 Query: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL Sbjct: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300 Query: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS Sbjct: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360 Query: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL Sbjct: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420 Query: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN Sbjct: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480 Query: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS Sbjct: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540 Query: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQ 600 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCT FHLNITLPKDKVWQKDEEYTW+LNPEHLQ Sbjct: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600 Query: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR Sbjct: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660 Query: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK Sbjct: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720 Query: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC Sbjct: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780 Query: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF Sbjct: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840 Query: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF Sbjct: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900 Query: 901 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960 TR+QRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI Sbjct: 901 TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960 Query: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL Sbjct: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020 Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080 Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140 Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200 Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260 ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAPA Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNNPVYVAPA 1260 Query: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ Sbjct: 1261 INSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQ 1320 Query: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG Sbjct: 1321 FSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDEG 1380 Query: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR Sbjct: 1381 QLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIMR 1440 Query: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN Sbjct: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500 Query: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL Sbjct: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560 Query: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR Sbjct: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620 Query: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE Sbjct: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680 Query: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP Sbjct: 1681 RKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731 >gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo sapiens] Length = 1732 Score = 3487 bits (9041), Expect = 0.0 Identities = 1726/1732 (99%), Positives = 1729/1732 (99%), Gaps = 1/1732 (0%) Query: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH Sbjct: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60 Query: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI Sbjct: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120 Query: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP Sbjct: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180 Query: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS Sbjct: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240 Query: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQ+ASGQVIDEIAGNFSRAVHGLQALNKL Sbjct: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQEASGQVIDEIAGNFSRAVHGLQALNKL 300 Query: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS Sbjct: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360 Query: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL Sbjct: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420 Query: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480 LLSRQNIS+LPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN Sbjct: 421 LLSRQNISSLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480 Query: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS Sbjct: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540 Query: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQ 600 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTW+LNPEHLQ Sbjct: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600 Query: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR Sbjct: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660 Query: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK Sbjct: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720 Query: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC Sbjct: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780 Query: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF Sbjct: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840 Query: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF Sbjct: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900 Query: 901 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI Sbjct: 901 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960 Query: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL Sbjct: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020 Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080 Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140 Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALY LELSKDQATSWMISIILSVLQNIF Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYRLELSKDQATSWMISIILSVLQNIF 1200 Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENE-XTKRILALLAKCSSSVPGSRDKNNPVYVAP 1259 ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAP Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNNPVYVAP 1260 Query: 1260 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1319 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH Sbjct: 1261 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1320 Query: 1320 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1379 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE Sbjct: 1321 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1380 Query: 1380 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1439 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM Sbjct: 1381 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1440 Query: 1440 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1499 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR Sbjct: 1441 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1500 Query: 1500 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1559 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV Sbjct: 1501 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1560 Query: 1560 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1619 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY Sbjct: 1561 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1620 Query: 1620 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1679 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK Sbjct: 1621 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1680 Query: 1680 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP Sbjct: 1681 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1732 >gi|31559825 polycystin 1-like 3 [Homo sapiens] Length = 1732 Score = 3486 bits (9040), Expect = 0.0 Identities = 1726/1732 (99%), Positives = 1728/1732 (99%), Gaps = 1/1732 (0%) Query: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH Sbjct: 1 MFFKGGSWLWLYIRTSIILGSELNSPAPHGQNNCYQLNRFQCSFEEAQHYCHVQRGFLAH 60 Query: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI Sbjct: 61 IWNKEVQDLIRDYLEEGKKWWIGQNVMPLKKHQDNKYPADVAANGPPKPLSCTYLSRNFI 120 Query: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP Sbjct: 121 RISSKGDKCLLKYYFICQTGDFLDGDAHYERNGNNSHLYQRHKKTKRGVAIARDKMPPGP 180 Query: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLPSITSQVTSAASEPSSQPLPVITQLTMPVS 240 GHLPTTCHYPLPAHLSKTLCHPISQFPSVL SITSQVTSAASEPSSQPLPVITQLTMPVS Sbjct: 181 GHLPTTCHYPLPAHLSKTLCHPISQFPSVLSSITSQVTSAASEPSSQPLPVITQLTMPVS 240 Query: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL Sbjct: 241 VTHAGQSLAETTSSPKEEGHPNTFTSYLQVSLQKASGQVIDEIAGNFSRAVHGLQALNKL 300 Query: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS Sbjct: 301 QEACEFLQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHS 360 Query: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL Sbjct: 361 LNNVTKAGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPESSVTLTSANATL 420 Query: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN Sbjct: 421 LLSRQNISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDN 480 Query: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS Sbjct: 481 RNIVGSIGSVLLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTS 540 Query: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQ 600 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCT FHLNITLPKDKVWQKDEEYTW+LNPEHLQ Sbjct: 541 LEKSLIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQ 600 Query: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR Sbjct: 601 HGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILR 660 Query: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK Sbjct: 661 TQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARK 720 Query: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC Sbjct: 721 KDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLC 780 Query: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF Sbjct: 781 DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHF 840 Query: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF Sbjct: 841 LCNCWLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQF 900 Query: 901 TRIQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960 TR+QRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI Sbjct: 901 TRVQRLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPI 960 Query: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL Sbjct: 961 NLVIGRLFPLIEPQETLPLFPPIQASCLSDASVEPLSATMVVEELKETVRFLLRRNTYLL 1020 Query: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL Sbjct: 1021 SKCEQPPWSSWDITKLVKLLSSLVSSHLEGQGCHQQGERHWARVVPENHHHFCCYLHRVL 1080 Query: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE Sbjct: 1081 QRLKSHLGTLGLTQGHQSCDFLDAASQLQKLQELLETHILPTEQEPSREVTSFAILSSEE 1140 Query: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF Sbjct: 1141 GKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIF 1200 Query: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENE-XTKRILALLAKCSSSVPGSRDKNNPVYVAP 1259 ISQPVKVVFFTFLYSLMMSRMPRLNKENE TKRILALLAKCSSSVPGSRDKNNPVYVAP Sbjct: 1201 ISQPVKVVFFTFLYSLMMSRMPRLNKENEQQTKRILALLAKCSSSVPGSRDKNNPVYVAP 1260 Query: 1260 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1319 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH Sbjct: 1261 AINSPTKHPERTLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH 1320 Query: 1320 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1379 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE Sbjct: 1321 QFSEIKLLQDFYPWANHILLPSLYGDYRGKNAVLEPSHCKCGVQLIFQIPRTKTYEKVDE 1380 Query: 1380 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1439 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM Sbjct: 1381 GQLAFCDNGHTCGRPKSLFPGLHLRRFSYICSPRPMVLIPTDELHERLTSKNENGFSYIM 1440 Query: 1440 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1499 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR Sbjct: 1441 RGAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKR 1500 Query: 1500 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1559 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV Sbjct: 1501 NILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPV 1560 Query: 1560 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1619 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY Sbjct: 1561 LLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDY 1620 Query: 1620 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1679 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK Sbjct: 1621 RTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGK 1680 Query: 1680 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1731 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP Sbjct: 1681 ERKSLKKEAALIDTLLQKLSNLLGISWPQKTSSEQAATTAVGSDTEVLDELP 1732 >gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] Length = 2459 Score = 536 bits (1381), Expect = e-152 Identities = 354/1139 (31%), Positives = 583/1139 (51%), Gaps = 67/1139 (5%) Query: 248 LAETTSSPKEEGHPNTFTSY-LQVSLQKASGQVIDEIAGNFSRAVHGLQALNKLQEACEF 306 LA+ SS + H + + L + +++ +V + + G+ S GL+ + ++QE E Sbjct: 898 LAKAVSSMLNQEHESQGSGQSLSIDVRQ---KVREHVLGSLSAVTTGLEDVQRVQELAEV 954 Query: 307 LQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHSLNNVTK 366 L+++T + + AQ +L + SE LL + + + T F ++ +V + Sbjct: 955 LREVTCRSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLE 1014 Query: 367 AGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPES-SVTLTSANATLLLSRQ 425 A + E + + L+ + L + P L + + ++ +R Sbjct: 1015 ASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRI 1074 Query: 426 NISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDNRNIVG 485 + SS P+A +L L V+++I +PF + ++ G Sbjct: 1075 QPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSG 1134 Query: 486 SIGSV-LLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTSLEKS 544 ++G + + S + +L+ V +L E+IEI+L R+ + PT LN+++ + + VNVTS E + Sbjct: 1135 TVGGLRVTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPE-ALWVNVTSGEAT 1193 Query: 545 LIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQHGIG 604 L + + + +TL LG+ Y PN + + L + DE TW+L+P+ L+ G G Sbjct: 1194 LGIQLHWRPDIALTLSLGYGYHPNKSSYDAQTHLVP--MVAPDELPTWILSPQDLRFGEG 1251 Query: 605 TYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCL 664 YY+T V E A V + T ++ C +W+ +TW +GCQVGP+++ +T CL Sbjct: 1252 VYYLTVVPESDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCL 1311 Query: 665 CNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQA 724 CNHLTFF S F V+ +N+ T +LF +NPV V+ + L YV+ V+WAR+KD Sbjct: 1312 CNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQ 1371 Query: 725 DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784 D KVKVTVL DNDP AQ+HYL+ VYTG+RR AAT++KV +TLYG +G EPHHL DP Sbjct: 1372 DQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT 1431 Query: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844 VFERG +D FLL+T LG L SLRLWHDNSG PSWYVS+V+V D+ + RKW+FLCN Sbjct: 1432 PVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNS 1491 Query: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRIQ 904 WL++++GDC LD+VF ++++ F HLF F ++W SI +R + FTR+Q Sbjct: 1492 WLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQ 1551 Query: 905 RLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPINLVI 964 R+SCC +LLLC M+ ++MFW + A++ + W E+++ + +++++FPINL+I Sbjct: 1552 RVSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLI 1611 Query: 965 GRLFPLIEPQETLPLFPPIQASCLSD-------ASVEPLSATMVVEE--LKETVRFLLRR 1015 ++F Q T P Q + D S +P+ ++ E K+ R + Sbjct: 1612 VQIF-----QNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSL 1666 Query: 1016 NTYLLSKCEQPPWSS---WDITKLVKLLSSLV-SSHLEGQGCHQQGERH----------- 1060 L W S DI L+ L+ ++ + GQ ++ ++ Sbjct: 1667 FKALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSS 1726 Query: 1061 ------------WARVVP--ENHHHFCCYLHRVLQRLKSHLGTLGLTQGHQSCDFLDAAS 1106 AR P ++ + C YL L+ ++ L +G Q A Sbjct: 1727 EMKEKSQCPKPKAARSGPWKDSAYRQCLYLQ--LEHVEQELRLVGPRGFSQPHSHAQALR 1784 Query: 1107 QLQKLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSL 1166 QLQ L+ L + P P A S+ + KP GL W V WLL+ TS Sbjct: 1785 QLQTLKGGL--GVQPGTWAP-------AHASALQVSKP-PQGLPWWCILVGWLLVAATSG 1834 Query: 1167 ASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK 1226 +AFFT LY L + + W+IS+ +S ++++F++QP+KV+ F ++L++ R+ ++ Sbjct: 1835 VAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRVD--DE 1892 Query: 1227 ENEXTKRILALLAKCSSSV-PGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTGDIL 1285 E+ LL ++ R+ + VY P + K LK++K F L +IL Sbjct: 1893 EDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREIL 1952 Query: 1286 VQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYG 1344 + FL +L+ Y ++ + ++L++ + +F+ FS + ++F+ WAN L+ +LYG Sbjct: 1953 AYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNLYG 2011 Score = 203 bits (517), Expect = 1e-51 Identities = 102/266 (38%), Positives = 171/266 (64%), Gaps = 2/266 (0%) Query: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500 G FFT L+S + + + +++IY+L + YY +QG ++ ++ W +F K N Sbjct: 2162 GTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWN 2221 Query: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560 +L+ +IIL S+ L + +K L ++++ R R+ ++ ISF E ++A +++ F VL Sbjct: 2222 LLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVL 2281 Query: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620 L+TV+LW+LLR +P++ +I+ L RAW ++ GF+++IL +L Y+IA NL+FG + Y+ Sbjct: 2282 LSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYK 2341 Query: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680 T F +A T+V L +GI + EEV PVLG+FLI + ++ M VV+NLF+S IL+AF +E Sbjct: 2342 TLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSEE 2401 Query: 1681 RK--SLKKEAALIDTLLQKLSNLLGI 1704 +K L +E ++D LL K+ + LGI Sbjct: 2402 QKYYQLSEEGEIVDLLLMKILSFLGI 2427 Score = 38.9 bits (89), Expect = 0.044 Identities = 15/50 (30%), Positives = 28/50 (56%) Query: 34 CYQLNRFQCSFEEAQHYCHVQRGFLAHIWNKEVQDLIRDYLEEGKKWWIG 83 CY+ +F +AQ +C Q G L I ++ Q ++ ++ + ++WWIG Sbjct: 39 CYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWIG 88 >gi|5174633 receptor for egg jelly-like protein precursor [Homo sapiens] Length = 2253 Score = 182 bits (463), Expect = 2e-45 Identities = 114/393 (29%), Positives = 188/393 (47%), Gaps = 37/393 (9%) Query: 625 LVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCN------------------ 666 LV + QC W C +G +++ C+C Sbjct: 1094 LVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTGIH 1153 Query: 667 -HLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQAD 725 H + + V+P V++ + + + NPV + + ++ YV WA +D+ D Sbjct: 1154 LHTHYVMAKVIVIPNPVDLR--LNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMD 1211 Query: 726 MQ-KVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784 + V VL DNDP YL+ ++TG R + T A V + L G+ S+ H L P Sbjct: 1212 QHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHF 1271 Query: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844 T RG ++ FLLTT + LG++HS+R+WH+N G SPSWY+S++ V ++ + W F+C Sbjct: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331 Query: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRIQ 904 WL+V D LDR F E + + F + ++++W SI F R+Q Sbjct: 1332 WLSV---DTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQ 1388 Query: 905 RLSCCMTLLLCNMVINVMFWKIN---STTAKRDEQMRPFAVAWSELLVSIHTAVILFPIN 961 RLSCC+ +LL +++ N+MF+ +N T ++ + MR +++ I + +I P+ Sbjct: 1389 RLSCCLAMLLSSLLCNIMFFNLNRQEQTESRERKYMR-------SMMIGIESVLITIPVQ 1441 Query: 962 LVIGRLFPLIE--PQETLPLFPPIQASCLSDAS 992 L+I LF + PQ L P + +S+AS Sbjct: 1442 LLITFLFTCSQRKPQADLKEVSPQKHPLMSEAS 1474 Score = 76.6 bits (187), Expect = 2e-13 Identities = 70/267 (26%), Positives = 115/267 (43%), Gaps = 24/267 (8%) Query: 1122 TEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSK 1181 +EQ PS++ ++ KK L W V W L+ TS S+FF Y L Sbjct: 1552 SEQHPSQK-------DLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGY 1604 Query: 1182 DQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK------ENEXTKRIL 1235 D++ W+ + S Q++ + QP K++ L S + P+ K + + T+ L Sbjct: 1605 DKSIEWLFASFCSFCQSVLLVQPSKII----LLSGFRTNKPKYCKNLSWSTKYKYTEIRL 1660 Query: 1236 ALLAKCSSSVPGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFK-----LTGDILVQILF 1290 + + D+ + T+ R K+KK K IL +F Sbjct: 1661 DGMRMHPEEMQRIHDQIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIF 1720 Query: 1291 LTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYGDYRGKN 1350 L LL+ I ++++ FY +Q I FS + + L+D Y W N +LLP L+ D Sbjct: 1721 LALLLILIVLLRHTDCFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDL-NPT 1779 Query: 1351 AVLEPSHCKCGVQLIFQIPRTKTYEKV 1377 + E S G+ L+ Q+ R K+ EK+ Sbjct: 1780 FLPESSSKILGLPLMRQV-RAKSSEKM 1805 Score = 68.6 bits (166), Expect = 5e-11 Identities = 54/255 (21%), Positives = 116/255 (45%), Gaps = 6/255 (2%) Query: 1435 FSYIMRGAFFTSLRLESFTSLQMSKKGC--VWSIISQVIYYLLVCYYAFIQGCQLKQQKW 1492 F G TS+ L SF+ +K ++ ++ +I++L Y +GC + Q++ Sbjct: 1935 FEVSQLGVVNTSISLHSFSLADFDRKASAEIYLYVAILIFFLA---YVVDEGCIIMQERA 1991 Query: 1493 RFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAAT 1552 + N+L+ ++ I +L+ L ++ L + Y + + FI F+ +V+ Sbjct: 1992 SYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNPEDFIPFHAVSQVDHIMR 2051 Query: 1553 HLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLF 1612 ++GF + L ++ R +R+ R + A + ++ + Y L+F Sbjct: 2052 IILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVF 2111 Query: 1613 GCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSA 1672 G +Y S TV + + Q F+ + +LG + + +++M+ V+INLF + Sbjct: 2112 GQHEWNYSNLIHSTQTVFSYCVS-AFQNTEFSNNRILGVLFLSSFMLVMICVLINLFQAV 2170 Query: 1673 ILMAFGKERKSLKKE 1687 IL A+ + ++ + +E Sbjct: 2171 ILSAYEEMKQPVYEE 2185 >gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] Length = 4302 Score = 179 bits (455), Expect = 2e-44 Identities = 207/850 (24%), Positives = 360/850 (42%), Gaps = 68/850 (8%) Query: 532 LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEE-Y 590 L + +N T L+ + S +P+ L +YL + +PN + + + + D Y Sbjct: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976 Query: 591 TWMLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650 T+ ++P + G+Y++ R Q VSV + C Y+ + W + G Sbjct: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030 Query: 651 QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707 +++ + CL HLT F + FV P R V E T + N + + A Sbjct: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084 Query: 708 LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767 L Y++ K DQ D + + +F Y I V TG+ R + TTA V I L Sbjct: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142 Query: 768 YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827 YG + RS HL + F R LD+F + T SLG++ +R+WHDN G+SP+W++ V Sbjct: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200 Query: 828 IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885 IV D+ R FL N WL+V + +++ + S L FR L + + F Sbjct: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260 Query: 886 YLWLSIATRHPWNQFTRIQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944 ++WLSI R P ++FTRIQR +CC+ L+ + N V + + + R ++ Sbjct: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320 Query: 945 SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDA- 991 + V + ++V+++P+ L I LF P Q+ L + + +S L + Sbjct: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSF 3380 Query: 992 -SVEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDITKLVKLLSSLVSSHLEG 1050 + L A V ++K + FL + + + S D+ ++ S + G Sbjct: 3381 LTFSGLHAEAFVGQMKSDL-FLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLRQLARG 3439 Query: 1051 QGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCDFLDAA 1105 Q H G E ++ P + F ++Q+ L + + TQ H D L + Sbjct: 3440 QAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSL 3499 Query: 1106 SQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLTSVCWL 1159 S + E L L PS + ++ + + GL K W S+ Sbjct: 3500 SSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHG 3559 Query: 1160 LLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMS 1219 L + + + +W++S S L + +P+KV+ +SL+ Sbjct: 3560 LSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAK 3619 Query: 1220 RMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLKKKKLF 1278 RL+ + + T + S+ VP R + +++A E K K+L Sbjct: 3620 ---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARKVKRLH 3667 Query: 1279 KLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDFYPWAN 1335 + +LV +LFL + + A Y ++ + + + L AI + S F I ++ +PW Sbjct: 3668 GMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMA 3727 Query: 1336 HILLPSLYGD 1345 H+LLP ++G+ Sbjct: 3728 HVLLPYVHGN 3737 Score = 38.1 bits (87), Expect = 0.075 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Query: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596 RF SF + +++SAA L + L V+ LR + V +TL RA E++G L Sbjct: 3972 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4031 Query: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649 +++L YA +A L+ C S + + V G + E + L P+L Sbjct: 4032 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4085 >gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] Length = 4303 Score = 179 bits (454), Expect = 2e-44 Identities = 211/855 (24%), Positives = 362/855 (42%), Gaps = 77/855 (9%) Query: 532 LTITVNVTSLEKSLIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEE-Y 590 L + +N T L+ + S +P+ L +YL + +PN + + + + D Y Sbjct: 2920 LHLQLNYTLLDGHYL-SEEPEPYL--AVYLHSEPRPNEHNCSASRRIRPESLQGADHRPY 2976 Query: 591 TWMLNPEHLQHGIGTYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGC 650 T+ ++P + G+Y++ R Q VSV + C Y+ + W + G Sbjct: 2977 TFFISPGS-RDPAGSYHLNLSSHFRWSALQ-----VSVGLYTSLCQYFSEEDMVWRTEGL 3030 Query: 651 QVGPQSTILRTQCLCNHLTFFASDFFVVP---RTVNVEDTIKLFLRVTNNPVGVSLLASL 707 +++ + CL HLT F + FV P R V E T + N + + A Sbjct: 3031 LPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADV------NYIVMLTCAVC 3084 Query: 708 LGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITL 767 L Y++ K DQ D + + +F Y I V TG+ R + TTA V I L Sbjct: 3085 LVTYMVMAAILHKLDQLDASRGRAIPFCGQ--RGRFKYEILVKTGWGRGSGTTAHVGIML 3142 Query: 768 YGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQV 827 YG + RS HL + F R LD+F + T SLG++ +R+WHDN G+SP+W++ V Sbjct: 3143 YGVDSRSGHRHLDGDR--AFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHV 3200 Query: 828 IVCDMAVKRKWHFLCNCWLAV--DLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQD 885 IV D+ R FL N WL+V + +++ + S L FR L + + F Sbjct: 3201 IVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDK 3260 Query: 886 YLWLSIATRHPWNQFTRIQRLSCCMTLLLCNMVIN-VMFWKINSTTAKRDEQMRPFAVAW 944 ++WLSI R P ++FTRIQR +CC+ L+ + N V + + + R ++ Sbjct: 3261 HIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSV 3320 Query: 945 SELLVSIHTAVILFPINLVIGRLF------------PLIEPQETLPLFPPIQASCLSDAS 992 + V + ++V+++P+ L I LF P Q+ L + SCL + Sbjct: 3321 DTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDI-----DSCLDSSV 3375 Query: 993 VEPLSATMVVEELKETVRFLLRRNTYLLSKCEQPPWSSWDIT-KLVKLLS--SLVSSHL- 1048 ++ T ++ ++ + +L W S + T LLS S+V S+L Sbjct: 3376 LDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLR 3435 Query: 1049 ---EGQGCHQQG--ERHWARVVPEN-HHHFCCYLHRVLQR-LKSHLGTLGLTQG-HQSCD 1100 GQ H G E ++ P + F ++Q+ L + + TQ H D Sbjct: 3436 QLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETD 3495 Query: 1101 FLDAASQLQ-KLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSK-----WLT 1154 L + S + E L L PS + ++ + + GL K W Sbjct: 3496 LLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCA 3555 Query: 1155 SVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLY 1214 S+ L + + + +W++S S L + +P+KV+ + Sbjct: 3556 SLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYF 3615 Query: 1215 SLMMSRMPRLNKENEXTKRILALLAKCSSSVPGSRDKNN-PVYVAPAINSPTKHPERTLK 1273 SL+ RL+ + + T + S+ VP R + +++A E K Sbjct: 3616 SLVAK---RLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLA---------KEEARK 3663 Query: 1274 KKKLFKLTGDILVQILFLTLLMTAIY--SAKNSNRFYLHQAI-WKTFSHQFSEIKLLQDF 1330 K+L + +LV +LFL + + A Y ++ + + + L AI + S F I ++ Sbjct: 3664 VKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEEL 3723 Query: 1331 YPWANHILLPSLYGD 1345 +PW H+LLP ++G+ Sbjct: 3724 WPWMAHVLLPYVHGN 3738 Score = 38.1 bits (87), Expect = 0.075 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Query: 1537 RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLI 1596 RF SF + +++SAA L + L V+ LR + V +TL RA E++G L Sbjct: 3973 RFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLG 4032 Query: 1597 ILILLTGYA-IAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVL 1649 +++L YA +A L+ C S + + V G + E + L P+L Sbjct: 4033 LVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWHLSPLL 4086 >gi|19923084 polycystin-1L1 [Homo sapiens] Length = 2849 Score = 121 bits (304), Expect = 5e-27 Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 5/280 (1%) Query: 634 QCYYWEIHNQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKLFLR 693 +C +W+ + W S P ++ + C + L FA + + V D KL Sbjct: 1690 RCLFWD--KREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSH 1747 Query: 694 VTNNPVGVSLLASLLGFYVITVVWARKKDQADMQKVKVTVLADNDPSAQFHYLIQVYTGY 753 N + ++ S++ Y V +R+ D + +K L + Y + + TG+ Sbjct: 1748 PENLLPSIFIMGSVI-LYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGF 1806 Query: 754 RRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWH 813 R A T+KV I L G G SE L P+K +FER F+L+ LG L +RLWH Sbjct: 1807 RAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWH 1866 Query: 814 DNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRHL 873 D+ G SP W++S V+V ++ + W F CWL+ D ++R + FR L Sbjct: 1867 DSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGG--LGFRKL 1924 Query: 874 FSSMIVEKFTQDYLWLSIATRHPWNQFTRIQRLSCCMTLL 913 F E ++WLS+ +R +++ RL+ +LL Sbjct: 1925 FYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLL 1964 Score = 61.2 bits (147), Expect = 8e-09 Identities = 60/235 (25%), Positives = 98/235 (41%), Gaps = 28/235 (11%) Query: 1137 SSEEGKKPI-SNGLSKWLTSVCWLLLGFTSLASAFFTALYSLELSKDQATSWMISIILSV 1195 S EG P S L W +S W + G SLA + T + ++Q W+ + LSV Sbjct: 2116 SGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSV 2175 Query: 1196 LQNIFISQPVKVVFFTFLYSLMMSRMPRLNKEN--EXTKRILALLAK---------CSSS 1244 + IFI+QP+ V ++ E+ E T+ + + LA+ S S Sbjct: 2176 VCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCS 2235 Query: 1245 VPGSRDKNNPVYVA--PAINSPTKHP----------ERTLKKKKLFKLTGDILVQILFLT 1292 +P + V A A + HP +R ++ + DI + IL L Sbjct: 2236 IPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLL 2295 Query: 1293 LLMTAIYSAKNSNRFYLHQAIWKTFSHQ----FSEIKLLQDFYPWANHILLPSLY 1343 LL+ IY + + + L+QAI K F+ ++ + D++ W+ LL LY Sbjct: 2296 LLLCVIYGRFSQDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLY 2350 >gi|4505835 polycystin 2 [Homo sapiens] Length = 968 Score = 84.3 bits (207), Expect = 9e-16 Identities = 47/221 (21%), Positives = 107/221 (48%), Gaps = 1/221 (0%) Query: 1469 QVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNM 1528 ++I+ + YY + +++ K +F N LD I+++S + +G+++ S + + + Sbjct: 477 EIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTS-NVEVL 535 Query: 1529 ARYRDDQDRFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWD 1588 ++ +DQ+ F +F ++ V ++L+ + + + +S T+SR Sbjct: 536 LQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAK 595 Query: 1589 EVVGFLLIILILLTGYAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPV 1648 ++ GF ++ I+ YA L+FG + D+ TF T +++G + E+ + V Sbjct: 596 DLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRV 655 Query: 1649 LGTFLILTSVILMVLVVINLFVSAILMAFGKERKSLKKEAA 1689 LG T V M +++N+F++ I + + + L ++ A Sbjct: 656 LGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKA 696 Score = 33.1 bits (74), Expect = 2.4 Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 1271 TLKKKKLFKLTGDILVQILFLTLLMTAIYSAKNSNRFY---------LHQAIWKTFSHQF 1321 T ++K L + +++ +LFL +L Y +SN +Y L + KT F Sbjct: 211 TNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNF 270 Query: 1322 SEIKLLQDFYPWANHILLPSLYGDYRGKN 1350 + ++DF+ + LL LY + N Sbjct: 271 KTLSSMEDFWKFTEGSLLDGLYWKMQPSN 299 >gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens] Length = 2211 Score = 81.3 bits (199), Expect = 8e-15 Identities = 46/111 (41%), Positives = 66/111 (59%), Gaps = 6/111 (5%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804 Y + TG R A T A V ITL+G G S L K+ FE+G +DVF + T ++G Sbjct: 45 YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVRT-NNVG 103 Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKR---KWHFLCNCWLAVDLGD 852 ++ +R+ HDN+G++ SWY+ VIV DM KR +++F CN WL+ GD Sbjct: 104 LIYKVRIEHDNTGLNASWYLDHVIVTDM--KRPHLRYYFNCNNWLSKVEGD 152 Score = 79.0 bits (193), Expect = 4e-14 Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 5/155 (3%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK-TVFERGGLDVFLLTTWTSL 803 Y + V T A T A V I ++G G S L FER D F SL Sbjct: 1825 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 1884 Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVS 863 G+L LR+WHDN G+ P W++S V V D + +HF C+CWL+ GD + R F + Sbjct: 1885 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFACAN 1944 Query: 864 KRELFSFRHLFSSMIVEK----FTQDYLWLSIATR 894 + +++E T++ +WL + R Sbjct: 1945 NKICDELEETTYEIVIETGNGGETRENVWLILEGR 1979 Score = 75.1 bits (183), Expect = 6e-13 Identities = 42/113 (37%), Positives = 64/113 (56%), Gaps = 2/113 (1%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804 Y ++VYTG A T A V I ++G G + L + +K FE+G D F+L LG Sbjct: 174 YEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRL-ENEKDNFEKGAEDRFILDA-PDLG 231 Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857 L + + H+N G S W++SQ+++ D+ KRK+ F N WLA+D D ++ R Sbjct: 232 QLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWLALDEDDGKIQR 284 Score = 73.2 bits (178), Expect = 2e-12 Identities = 41/117 (35%), Positives = 65/117 (55%), Gaps = 3/117 (2%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL--CDPQKTVFERGGLDVFLLTTWTS 802 Y +Q++TG A T AKV IT+YG G + +L + + FERG D F++ Sbjct: 1462 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-AD 1520 Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVF 859 LG ++ ++L HDNS WYV +V + + + ++ FLC WL++ D L+R+F Sbjct: 1521 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRLERLF 1577 Score = 70.9 bits (172), Expect = 1e-11 Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 3/122 (2%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSE-GRSEPHHLCDPQKT-VFERGGLDVFLLTTWTS 802 Y +QV TG A T A V +T+YG E G + L K+ FE+G D F + Sbjct: 1024 YEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYA-ID 1082 Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPV 862 LG L +R+ HDN+G W++ ++ + DM + ++F C WLAV+ D +L R +PV Sbjct: 1083 LGALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVEEDDGQLSRELLPV 1142 Query: 863 SK 864 + Sbjct: 1143 DE 1144 Score = 69.3 bits (168), Expect = 3e-11 Identities = 40/108 (37%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804 Y + V TGY A T A V +T++G+ G + L + +FERG D F L T LG Sbjct: 2094 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 2152 Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGD 852 L +RL HD+SG W V +V V + + F C WL GD Sbjct: 2153 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGD 2200 Score = 63.2 bits (152), Expect = 2e-09 Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 5/156 (3%) Query: 721 KDQADMQKVKVTVLADNDPSAQ-FHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL 779 KD+ D Q V+ + +D+ + + F Y I + TG A+T ++V I LYG + + L Sbjct: 661 KDKDDGQLVRELLPSDSSATLKNFRYHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQVL 720 Query: 780 C---DPQKTVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKR 836 + K FERG +D F L T ++GN++ L + HD++G+ SW++ V + + Sbjct: 721 LVSDNNLKDYFERGRVDEFTLET-LNIGNINRLVIGHDSTGMHASWFLGSVQIRVPRQGK 779 Query: 837 KWHFLCNCWLAVDLGDCELDRVFIPVSKRELFSFRH 872 ++ F N WL + D L+ P E+ H Sbjct: 780 QYTFPANRWLDKNQADGRLEVELYPSEVVEIQKLVH 815 Score = 62.0 bits (149), Expect = 5e-09 Identities = 44/127 (34%), Positives = 66/127 (51%), Gaps = 7/127 (5%) Query: 734 LADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKT---VFERG 790 L D S F I+ TG +++A T A V ITL+G++ + L KT FER Sbjct: 1168 LEQKDKSTTFSVTIK--TGVKKNAGTDANVFITLFGTQDDTGMT-LLKSSKTNSDKFERD 1224 Query: 791 GLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDL 850 +++F + T LG+L +RL HDN+G +P W+V V V ++ + F C WLA + Sbjct: 1225 SIEIFTVET-LDLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNE 1283 Query: 851 GDCELDR 857 D + R Sbjct: 1284 DDGSIIR 1290 Score = 61.6 bits (148), Expect = 6e-09 Identities = 33/92 (35%), Positives = 51/92 (55%), Gaps = 2/92 (2%) Query: 744 HYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSL 803 HY ++++TG A T+A+V + +YG +G++E L K VFER D F L + Sbjct: 815 HYEVEIWTGDVGGAGTSARVYMQIYGEKGKTEVLFLSSRSK-VFERASKDTFQLEA-ADV 872 Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVK 835 G ++ LRL H G PSW+V V + + V+ Sbjct: 873 GEVYKLRLGHTGEGFGPSWFVDTVWLRHLVVR 904 Score = 61.2 bits (147), Expect = 8e-09 Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 2/116 (1%) Query: 742 QFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWT 801 +F + + V+T + A T + + I +YG +GR++ L +P F+ G ++ F + Sbjct: 424 KFPWSLWVWTTDLKKAGTNSPIFIQIYGQKGRTD-EILLNPNNKWFKPGIIEKFRIEL-P 481 Query: 802 SLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857 LG + +R+WHD W++ ++ + + K K++F CN WL + D E+ R Sbjct: 482 DLGRFYKIRVWHDKRSSGSGWHLERMTLMNTLNKDKYNFNCNRWLDANEDDNEIVR 537 Score = 58.2 bits (139), Expect = 7e-08 Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 1/133 (0%) Query: 725 DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784 D K++ +L + Y++ V+TG R A T +K+ + +YG+ G + + Sbjct: 278 DDGKIQRDILVGGAETTAITYIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIF-LEG 336 Query: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844 VF+RG D+F + L L + + H N GV+ W+ +V++ + F C+ Sbjct: 337 GVFDRGRTDIFHIELAVLLSPLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSN 396 Query: 845 WLAVDLGDCELDR 857 WL D ++R Sbjct: 397 WLDEKKADGLIER 409 Score = 55.8 bits (133), Expect = 3e-07 Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 6/136 (4%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL--CDPQKTVFERGGLDVFLLTTWTS 802 Y + V TG A T A V + L+G G + L C +FE+G D F + + T Sbjct: 555 YHVTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIESVT- 613 Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCD--MAVKRKWHFLCNCWLAVDLGDCELDRVFI 860 + N+ +R+ HD G WY+ +V+V + F C WL D D +L R + Sbjct: 614 MRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLDKDKDDGQLVRELL 673 Query: 861 PV-SKRELFSFRHLFS 875 P S L +FR+ S Sbjct: 674 PSDSSATLKNFRYHIS 689 Score = 49.7 bits (117), Expect = 2e-05 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGR-SEPHHLCD---PQKTVFERGGLDVFLLTTW 800 Y I +YT +A T A + I +YG + ++ +LC QK FER F++ Sbjct: 1308 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 1367 Query: 801 TSLGNLHSLRLWHDNSGVSPSWYVSQV----IVCDMAVKRKWHFLCNCWLAVDLGDCELD 856 + +R+ H+N+G++P W+ S V ++ D F C+ WLA D + Sbjct: 1368 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSEDDKKTI 1427 Query: 857 RVFIP 861 R +P Sbjct: 1428 RELVP 1432 Score = 43.9 bits (102), Expect = 0.001 Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 2/103 (1%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804 Y + V+TG T + + +TLYG G +E L D +K FER D F++ + Sbjct: 1698 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEI-LDIA 1755 Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLA 847 +R+ D G P W++ ++++ +M F WL+ Sbjct: 1756 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 1798 >gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sapiens] Length = 1114 Score = 79.0 bits (193), Expect = 4e-14 Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 5/155 (3%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK-TVFERGGLDVFLLTTWTSL 803 Y + V T A T A V I ++G G S L FER D F SL Sbjct: 776 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 835 Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVS 863 G+L LR+WHDN G+ P W++S V V D + +HF C+CWL+ GD + R F + Sbjct: 836 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFACAN 895 Query: 864 KRELFSFRHLFSSMIVEK----FTQDYLWLSIATR 894 + +++E T++ +WL + R Sbjct: 896 NKICDELEETTYEIVIETGNGGETRENVWLILEGR 930 Score = 73.2 bits (178), Expect = 2e-12 Identities = 41/117 (35%), Positives = 65/117 (55%), Gaps = 3/117 (2%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHL--CDPQKTVFERGGLDVFLLTTWTS 802 Y +Q++TG A T AKV IT+YG G + +L + + FERG D F++ Sbjct: 351 YSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTADTFIIEA-AD 409 Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVF 859 LG ++ ++L HDNS WYV +V + + + ++ FLC WL++ D L+R+F Sbjct: 410 LGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKEDGRLERLF 466 Score = 62.0 bits (149), Expect = 5e-09 Identities = 44/127 (34%), Positives = 66/127 (51%), Gaps = 7/127 (5%) Query: 734 LADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKT---VFERG 790 L D S F I+ TG +++A T A V ITL+G++ + L KT FER Sbjct: 57 LEQKDKSTTFSVTIK--TGVKKNAGTDANVFITLFGTQDDTGMT-LLKSSKTNSDKFERD 113 Query: 791 GLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDL 850 +++F + T LG+L +RL HDN+G +P W+V V V ++ + F C WLA + Sbjct: 114 SIEIFTVET-LDLGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNE 172 Query: 851 GDCELDR 857 D + R Sbjct: 173 DDGSIIR 179 Score = 57.4 bits (137), Expect = 1e-07 Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 3/117 (2%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEG-RSEPHHLCDPQ-KTVFERGGLDVFLLTTWTS 802 Y + V TG + AAT ++ I L G + RS+ L P+ K F RG ++ F + Sbjct: 518 YYVSVTTGKHKDAATDSRAFIFLIGEDDERSKRIWLDYPRGKRGFSRGSVEEFYVAG-LD 576 Query: 803 LGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVF 859 +G + + L HD + W V ++ + K+ CNCWLA D GD RVF Sbjct: 577 VGIIKKIELGHDGASPESCWLVEELCLAVPTQGTKYMLNCNCWLAKDRGDGITSRVF 633 Score = 49.7 bits (117), Expect = 2e-05 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 8/125 (6%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGR-SEPHHLCD---PQKTVFERGGLDVFLLTTW 800 Y I +YT +A T A + I +YG + ++ +LC QK FER F++ Sbjct: 197 YEITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASRFIVELE 256 Query: 801 TSLGNLHSLRLWHDNSGVSPSWYVSQV----IVCDMAVKRKWHFLCNCWLAVDLGDCELD 856 + +R+ H+N+G++P W+ S V ++ D F C+ WLA D + Sbjct: 257 DVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATSEDDKKTI 316 Query: 857 RVFIP 861 R +P Sbjct: 317 RELVP 321 Score = 43.9 bits (102), Expect = 0.001 Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 2/103 (1%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804 Y + V+TG T + + +TLYG G +E L D +K FER D F++ + Sbjct: 649 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEI-LDIA 706 Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLA 847 +R+ D G P W++ ++++ +M F WL+ Sbjct: 707 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 749 Score = 43.1 bits (100), Expect = 0.002 Identities = 21/55 (38%), Positives = 29/55 (52%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTT 799 Y + V TGY A T A V +T++G+ G + L + +FERG D F L T Sbjct: 1045 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET 1099 >gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sapiens] Length = 512 Score = 79.0 bits (193), Expect = 4e-14 Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 5/155 (3%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK-TVFERGGLDVFLLTTWTSL 803 Y + V T A T A V I ++G G S L FER D F SL Sbjct: 126 YTVAVKTSDILGAGTDANVFIIIFGENGDSGTLALKQSANWNKFERNNTDTFNFPDMLSL 185 Query: 804 GNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFIPVS 863 G+L LR+WHDN G+ P W++S V V D + +HF C+CWL+ GD + R F + Sbjct: 186 GHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDETFHFQCDCWLSKSEGDGQTVRDFACAN 245 Query: 864 KRELFSFRHLFSSMIVEK----FTQDYLWLSIATR 894 + +++E T++ +WL + R Sbjct: 246 NKICDELEETTYEIVIETGNGGETRENVWLILEGR 280 Score = 69.3 bits (168), Expect = 3e-11 Identities = 40/108 (37%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804 Y + V TGY A T A V +T++G+ G + L + +FERG D F L T LG Sbjct: 395 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLET-LELG 453 Query: 805 NLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGD 852 L +RL HD+SG W V +V V + + F C WL GD Sbjct: 454 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGD 501 Score = 42.4 bits (98), Expect = 0.004 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 2/99 (2%) Query: 749 VYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLGNLHS 808 V+TG T + + +TLYG G +E L D +K FER D F++ + Sbjct: 3 VWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEI-LDIAPFTK 60 Query: 809 LRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLA 847 +R+ D G P W++ ++++ +M F WL+ Sbjct: 61 MRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLS 99 >gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] Length = 805 Score = 75.1 bits (183), Expect = 6e-13 Identities = 54/242 (22%), Positives = 112/242 (46%), Gaps = 13/242 (5%) Query: 1469 QVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNM 1528 +VI+ + + YY + +L + R+ + NILD +IL+S + +G + + M Sbjct: 356 EVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLM 415 Query: 1529 ARYRDDQD-----RFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTL 1583 + + F++F++ N A +L A ++++ + + + +S TL Sbjct: 416 GKLLQQPNTYADFEFLAFWQTQYNNMNAVNL-----FFAWIKIFKYISFNKTMTQLSSTL 470 Query: 1584 SRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVF 1643 +R +++GF ++ I+ YA LLFG + ++ TF T +++G + Sbjct: 471 ARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAID 530 Query: 1644 ALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKERKSL---KKEAALIDTLLQKLSN 1700 + +LG +T V + V++N+F++ I + + ++ L K E L D L Q + Sbjct: 531 NANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNK 590 Query: 1701 LL 1702 L Sbjct: 591 TL 592 Score = 34.7 bits (78), Expect = 0.83 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 9/84 (10%) Query: 1269 ERTLKKKKLFKLTG--DILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSH------- 1319 E T + ++L+ T ++LV I+FL + Y +S+ +Y + + + F H Sbjct: 87 ENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGV 146 Query: 1320 QFSEIKLLQDFYPWANHILLPSLY 1343 F I + DF+ +A LL SLY Sbjct: 147 SFQAISSMADFWDFAQGPLLDSLY 170 >gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens] Length = 613 Score = 67.0 bits (162), Expect = 2e-10 Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 4/201 (1%) Query: 1477 CYYAFIQGCQ----LKQQKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYR 1532 C + F+ Q +K+ K +F N L+ ++L+ F+ + + + + Sbjct: 290 CIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLL 349 Query: 1533 DDQDRFISFYEAVKVNSAATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVG 1592 +++ FY + +++ + A ++++ + + + +S TLSR ++VG Sbjct: 350 KSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVG 409 Query: 1593 FLLIILILLTGYAIAFNLLFGCSISDYRTFFSSAVTVVGLLMGISHQEEVFALDPVLGTF 1652 F ++ I+ YA L+FG + D+ TF +S +++G + + +P+LG Sbjct: 410 FAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPI 469 Query: 1653 LILTSVILMVLVVINLFVSAI 1673 +T + + V++N+F++ I Sbjct: 470 YFITFIFFVFFVLLNMFLAII 490 >gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] Length = 1029 Score = 58.2 bits (139), Expect = 7e-08 Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 5/151 (3%) Query: 710 FYVITVVW-ARKKDQADMQKVKVTVLADNDPSAQFH-YLIQVYTGYRRSAATTAKVVITL 767 FYV W AR ++ ++ + + +L+ P Y + V TG +A T A V I++ Sbjct: 7 FYVPVQRWLARDQEDGEICR-EFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISI 65 Query: 768 YGSEGRSEPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQ 826 +G +G + L + + F RG D F L LG+L + + HD G W++ Sbjct: 66 HGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHLGDLCKIVIGHDGLGPGNGWFLDD 124 Query: 827 VIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857 V++ D ++ F C+ WL DC++ R Sbjct: 125 VVIKDPTTNYEYAFFCHRWLDQGEDDCKIVR 155 Score = 50.4 bits (119), Expect = 1e-05 Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 4/129 (3%) Query: 716 VWARKKDQADMQKV-KVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRS 774 VW + QAD V ++ V+ Y + VYTG + A T ++V + L+G G S Sbjct: 607 VWL-SRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDS 665 Query: 775 EPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMA 833 L V F+RG +D F + SLG L + L + S S WY QVIV + Sbjct: 666 GLRQLYKSNMQVKFQRGQIDKFQVAA-VSLGKLQKVLLRCEASDKSQYWYCEQVIVREPG 724 Query: 834 VKRKWHFLC 842 + F C Sbjct: 725 TTSESIFTC 733 >gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo sapiens] Length = 1029 Score = 58.2 bits (139), Expect = 7e-08 Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 5/151 (3%) Query: 710 FYVITVVW-ARKKDQADMQKVKVTVLADNDPSAQFH-YLIQVYTGYRRSAATTAKVVITL 767 FYV W AR ++ ++ + + +L+ P Y + V TG +A T A V I++ Sbjct: 7 FYVPVQRWLARDQEDGEICR-EFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISI 65 Query: 768 YGSEGRSEPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQ 826 +G +G + L + + F RG D F L LG+L + + HD G W++ Sbjct: 66 HGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHLGDLCKIVIGHDGLGPGNGWFLDD 124 Query: 827 VIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857 V++ D ++ F C+ WL DC++ R Sbjct: 125 VVIKDPTTNYEYAFFCHRWLDQGEDDCKIVR 155 Score = 50.4 bits (119), Expect = 1e-05 Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 4/129 (3%) Query: 716 VWARKKDQADMQKV-KVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRS 774 VW + QAD V ++ V+ Y + VYTG + A T ++V + L+G G S Sbjct: 607 VWL-SRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDS 665 Query: 775 EPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMA 833 L V F+RG +D F + SLG L + L + S S WY QVIV + Sbjct: 666 GLRQLYKSNMQVKFQRGQIDKFQVAA-VSLGKLQKVLLRCEASDKSQYWYCEQVIVREPG 724 Query: 834 VKRKWHFLC 842 + F C Sbjct: 725 TTSESIFTC 733 >gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo sapiens] Length = 1029 Score = 58.2 bits (139), Expect = 7e-08 Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 5/151 (3%) Query: 710 FYVITVVW-ARKKDQADMQKVKVTVLADNDPSAQFH-YLIQVYTGYRRSAATTAKVVITL 767 FYV W AR ++ ++ + + +L+ P Y + V TG +A T A V I++ Sbjct: 7 FYVPVQRWLARDQEDGEICR-EFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISI 65 Query: 768 YGSEGRSEPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQ 826 +G +G + L + + F RG D F L LG+L + + HD G W++ Sbjct: 66 HGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLEA-VHLGDLCKIVIGHDGLGPGNGWFLDD 124 Query: 827 VIVCDMAVKRKWHFLCNCWLAVDLGDCELDR 857 V++ D ++ F C+ WL DC++ R Sbjct: 125 VVIKDPTTNYEYAFFCHRWLDQGEDDCKIVR 155 Score = 50.4 bits (119), Expect = 1e-05 Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 4/129 (3%) Query: 716 VWARKKDQADMQKV-KVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRS 774 VW + QAD V ++ V+ Y + VYTG + A T ++V + L+G G S Sbjct: 607 VWL-SRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDS 665 Query: 775 EPHHLCDPQKTV-FERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMA 833 L V F+RG +D F + SLG L + L + S S WY QVIV + Sbjct: 666 GLRQLYKSNMQVKFQRGQIDKFQVAA-VSLGKLQKVLLRCEASDKSQYWYCEQVIVREPG 724 Query: 834 VKRKWHFLC 842 + F C Sbjct: 725 TTSESIFTC 733 >gi|229093087 G protein-coupled receptor 97 [Homo sapiens] Length = 549 Score = 47.0 bits (110), Expect = 2e-04 Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 15/90 (16%) Query: 635 CYYWEIHNQT---WSSAGC--QVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIK 689 C +W++ T WSS GC +V P+ T+ C C+HLTFFA ++ R + T+ Sbjct: 215 CVFWDVTKGTTGDWSSEGCSTEVRPEGTV----CCCDHLTFFA----LLLRPTLDQSTVH 266 Query: 690 LFLRVTNNPVGVSLLASLLGFYVITVVWAR 719 + R++ GVS++ L F +I + R Sbjct: 267 ILTRISQAGCGVSMI--FLAFTIILYAFLR 294 >gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] Length = 674 Score = 46.2 bits (108), Expect = 3e-04 Identities = 26/83 (31%), Positives = 41/83 (49%) Query: 745 YLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQKTVFERGGLDVFLLTTWTSLG 804 Y + V TG + A T + ++L GS G SE H L P FERG +D + +T LG Sbjct: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63 Query: 805 NLHSLRLWHDNSGVSPSWYVSQV 827 + +R+ ++ WY+ + Sbjct: 64 EIQLVRIEKRKYWLNDDWYLKYI 86 >gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapiens] Length = 1079 Score = 45.4 bits (106), Expect = 5e-04 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 9/87 (10%) Query: 635 CYYWEIH----NQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKL 690 C +W+ WS GCQ S QCLC HLT F+ + P TV E + L Sbjct: 715 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFS--VLMSPHTVPEEPALAL 772 Query: 691 FLRVTNNPVGVSLLASLLGFYVITVVW 717 +V +G S+LA L+ V +VW Sbjct: 773 LTQV---GLGASILALLVCLGVYWLVW 796 >gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapiens] Length = 997 Score = 45.4 bits (106), Expect = 5e-04 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 9/87 (10%) Query: 635 CYYWEIH----NQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKL 690 C +W+ WS GCQ S QCLC HLT F+ + P TV E + L Sbjct: 646 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFS--VLMSPHTVPEEPALAL 703 Query: 691 FLRVTNNPVGVSLLASLLGFYVITVVW 717 +V +G S+LA L+ V +VW Sbjct: 704 LTQV---GLGASILALLVCLGVYWLVW 727 >gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapiens] Length = 873 Score = 45.4 bits (106), Expect = 5e-04 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 9/87 (10%) Query: 635 CYYWEIH----NQTWSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDTIKL 690 C +W+ WS GCQ S QCLC HLT F+ + P TV E + L Sbjct: 516 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFS--VLMSPHTVPEEPALAL 573 Query: 691 FLRVTNNPVGVSLLASLLGFYVITVVW 717 +V +G S+LA L+ V +VW Sbjct: 574 LTQV---GLGASILALLVCLGVYWLVW 597 >gi|27436974 potassium voltage-gated channel, Shab-related subfamily, member 2 [Homo sapiens] Length = 911 Score = 44.3 bits (103), Expect = 0.001 Identities = 46/209 (22%), Positives = 90/209 (43%), Gaps = 35/209 (16%) Query: 1491 KWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSA 1550 KW+FF G N++D IL ++ + L + S+ + R R + + +++ Sbjct: 258 KWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVR------RVVQIFRIMRI--- 308 Query: 1551 ATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNL 1610 +++ L RHS L+ + TL R+++E+ L+IL L G I +L Sbjct: 309 -------------LRILKLARHSTGLQSLGFTLRRSYNELG---LLILFLAMGIMIFSSL 352 Query: 1611 LFGCSISDYRTFFSSA------VTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVL- 1663 +F + T F+S T+ +G L ++G + V+++ L Sbjct: 353 VFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALP 412 Query: 1664 --VVINLFVSAILMAFGKERKSLKKEAAL 1690 +++N F S ++ K++K+ AL Sbjct: 413 IPIIVNNF-SEFYKEQKRQEKAIKRREAL 440 >gi|44889475 RAB6 interacting protein 1 [Homo sapiens] Length = 1287 Score = 43.5 bits (101), Expect = 0.002 Identities = 19/59 (32%), Positives = 32/59 (54%) Query: 802 SLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFI 860 +LG L ++++ HDNSG+ W V V+V + + F C WL + D L+R+ + Sbjct: 1004 NLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILV 1062 >gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] Length = 1274 Score = 43.5 bits (101), Expect = 0.002 Identities = 20/59 (33%), Positives = 32/59 (54%) Query: 802 SLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNCWLAVDLGDCELDRVFI 860 +LG L ++++ HDNSG+ W V V+V + + F C WL + D L+R+ I Sbjct: 986 NLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILI 1044 >gi|4826784 potassium voltage-gated channel, Shab-related subfamily, member 1 [Homo sapiens] Length = 858 Score = 42.4 bits (98), Expect = 0.004 Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 35/210 (16%) Query: 1490 QKWRFFTGKRNILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNS 1549 +KW+FF G N +D IL ++ + L + S+ + R R + + +++ Sbjct: 253 KKWKFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVR------RVVQIFRIMRI-- 304 Query: 1550 AATHLVGFPVLLATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFN 1609 +++ L RHS L+ + TL R+++E+ L+IL L G I + Sbjct: 305 --------------LRILKLARHSTGLQSLGFTLRRSYNELG---LLILFLAMGIMIFSS 347 Query: 1610 LLFGCSISDYRTFFSSA------VTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVL 1663 L+F + T F S T+ +G L ++G + V+++ L Sbjct: 348 LVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIAL 407 Query: 1664 ---VVINLFVSAILMAFGKERKSLKKEAAL 1690 +++N F S ++ K++K+ AL Sbjct: 408 PIPIIVNNF-SEFYKEQKRQEKAIKRREAL 436 >gi|224809323 G protein-coupled receptor 56 isoform b precursor [Homo sapiens] Length = 687 Score = 42.4 bits (98), Expect = 0.004 Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 17/109 (15%) Query: 634 QCYYWEIHNQT------WSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDT 687 QC +W + + T WSSAGC+ + T +T C CNHLT+FA ++ +V V+ Sbjct: 345 QCVFW-VEDPTLSSPGHWSSAGCETVRRET--QTSCFCNHLTYFA---VLMVSSVEVDAV 398 Query: 688 IKLFLRVTNNPVG--VSLLASLLGFYVITVVWARKKDQADMQKVKVTVL 734 K +L + + VG VS LA L+ + + +R+K + KV + +L Sbjct: 399 HKHYLSLLSY-VGCVVSALACLV--TIAAYLCSRRKPRDYTIKVHMNLL 444 >gi|224809320 G protein-coupled receptor 56 isoform c precursor [Homo sapiens] Length = 692 Score = 42.4 bits (98), Expect = 0.004 Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 17/109 (15%) Query: 634 QCYYWEIHNQT------WSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDT 687 QC +W + + T WSSAGC+ + T +T C CNHLT+FA ++ +V V+ Sbjct: 350 QCVFW-VEDPTLSSPGHWSSAGCETVRRET--QTSCFCNHLTYFA---VLMVSSVEVDAV 403 Query: 688 IKLFLRVTNNPVG--VSLLASLLGFYVITVVWARKKDQADMQKVKVTVL 734 K +L + + VG VS LA L+ + + +R+K + KV + +L Sbjct: 404 HKHYLSLLSY-VGCVVSALACLV--TIAAYLCSRRKPRDYTIKVHMNLL 449 >gi|224809318 G protein-coupled receptor 56 isoform b precursor [Homo sapiens] Length = 687 Score = 42.4 bits (98), Expect = 0.004 Identities = 36/109 (33%), Positives = 58/109 (53%), Gaps = 17/109 (15%) Query: 634 QCYYWEIHNQT------WSSAGCQVGPQSTILRTQCLCNHLTFFASDFFVVPRTVNVEDT 687 QC +W + + T WSSAGC+ + T +T C CNHLT+FA ++ +V V+ Sbjct: 345 QCVFW-VEDPTLSSPGHWSSAGCETVRRET--QTSCFCNHLTYFA---VLMVSSVEVDAV 398 Query: 688 IKLFLRVTNNPVG--VSLLASLLGFYVITVVWARKKDQADMQKVKVTVL 734 K +L + + VG VS LA L+ + + +R+K + KV + +L Sbjct: 399 HKHYLSLLSY-VGCVVSALACLV--TIAAYLCSRRKPRDYTIKVHMNLL 444 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.135 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 65,767,631 Number of Sequences: 37866 Number of extensions: 2976664 Number of successful extensions: 8077 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 78 Number of HSP's that attempted gapping in prelim test: 7819 Number of HSP's gapped (non-prelim): 284 length of query: 1731 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1615 effective length of database: 13,855,062 effective search space: 22375925130 effective search space used: 22375925130 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.