Guide to the Human Genome
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Search of human proteins with 239750617

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239750617 PREDICTED: hypothetical protein XP_002347474 [Homo
sapiens]
         (269 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239750617 PREDICTED: hypothetical protein XP_002347474 [Homo ...   533   e-152
gi|239744924 PREDICTED: hypothetical protein XP_002343309 [Homo ...   533   e-152
gi|239756804 PREDICTED: hypothetical protein [Homo sapiens]            32   0.58 
gi|239751298 PREDICTED: hypothetical protein XP_002347799 [Homo ...    32   0.58 
gi|239745795 PREDICTED: hypothetical protein XP_002343591 [Homo ...    32   0.58 
gi|239747203 PREDICTED: hypothetical protein LOC643965 [Homo sap...    30   2.9  
gi|239741003 PREDICTED: hypothetical protein LOC643965 [Homo sap...    30   2.9  
gi|239755210 PREDICTED: hypothetical protein [Homo sapiens]            29   3.8  
gi|239749699 PREDICTED: hypothetical protein XP_002347122 [Homo ...    29   3.8  
gi|239743965 PREDICTED: hypothetical protein XP_002344250 [Homo ...    29   3.8  
gi|167736355 mucin 4 isoform a [Homo sapiens]                          29   4.9  
gi|112382231 mucin 4 isoform e [Homo sapiens]                          29   4.9  
gi|112382233 mucin 4 isoform d [Homo sapiens]                          29   4.9  
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid...    28   8.4  
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide...    28   8.4  
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated...    28   8.4  
gi|73747887 ADAM metallopeptidase domain 12 isoform 2 preproprot...    28   8.4  
gi|73747885 ADAM metallopeptidase domain 12 isoform 1 preproprot...    28   8.4  
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       28   8.4  
gi|89242141 colon cancer-associated protein Mic1 [Homo sapiens]        28   8.4  

>gi|239750617 PREDICTED: hypothetical protein XP_002347474 [Homo
           sapiens]
          Length = 269

 Score =  533 bits (1373), Expect = e-152
 Identities = 269/269 (100%), Positives = 269/269 (100%)

Query: 1   MQQLHPLTSLNQLLLRQLPGPLCLLHHGTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCIV 60
           MQQLHPLTSLNQLLLRQLPGPLCLLHHGTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCIV
Sbjct: 1   MQQLHPLTSLNQLLLRQLPGPLCLLHHGTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCIV 60

Query: 61  QLNLGYLQQALEALDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGGL 120
           QLNLGYLQQALEALDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGGL
Sbjct: 61  QLNLGYLQQALEALDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGGL 120

Query: 121 QRVHHPQVVALGLFHLLVLLCQLPLDLCLDLVELQLGPEDLALLLLSDLLQLMDSLSAGT 180
           QRVHHPQVVALGLFHLLVLLCQLPLDLCLDLVELQLGPEDLALLLLSDLLQLMDSLSAGT
Sbjct: 121 QRVHHPQVVALGLFHLLVLLCQLPLDLCLDLVELQLGPEDLALLLLSDLLQLMDSLSAGT 180

Query: 181 QLLSQVGDLLCVGNTAFLSLKSSVLRERASFCEDSSSDCDSSYFCFHSARICPGTRLTLQ 240
           QLLSQVGDLLCVGNTAFLSLKSSVLRERASFCEDSSSDCDSSYFCFHSARICPGTRLTLQ
Sbjct: 181 QLLSQVGDLLCVGNTAFLSLKSSVLRERASFCEDSSSDCDSSYFCFHSARICPGTRLTLQ 240

Query: 241 PPSLSPMSRGCSSSIGALYVHHQVLDLIL 269
           PPSLSPMSRGCSSSIGALYVHHQVLDLIL
Sbjct: 241 PPSLSPMSRGCSSSIGALYVHHQVLDLIL 269


>gi|239744924 PREDICTED: hypothetical protein XP_002343309 [Homo
           sapiens]
          Length = 269

 Score =  533 bits (1373), Expect = e-152
 Identities = 269/269 (100%), Positives = 269/269 (100%)

Query: 1   MQQLHPLTSLNQLLLRQLPGPLCLLHHGTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCIV 60
           MQQLHPLTSLNQLLLRQLPGPLCLLHHGTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCIV
Sbjct: 1   MQQLHPLTSLNQLLLRQLPGPLCLLHHGTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCIV 60

Query: 61  QLNLGYLQQALEALDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGGL 120
           QLNLGYLQQALEALDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGGL
Sbjct: 61  QLNLGYLQQALEALDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGGL 120

Query: 121 QRVHHPQVVALGLFHLLVLLCQLPLDLCLDLVELQLGPEDLALLLLSDLLQLMDSLSAGT 180
           QRVHHPQVVALGLFHLLVLLCQLPLDLCLDLVELQLGPEDLALLLLSDLLQLMDSLSAGT
Sbjct: 121 QRVHHPQVVALGLFHLLVLLCQLPLDLCLDLVELQLGPEDLALLLLSDLLQLMDSLSAGT 180

Query: 181 QLLSQVGDLLCVGNTAFLSLKSSVLRERASFCEDSSSDCDSSYFCFHSARICPGTRLTLQ 240
           QLLSQVGDLLCVGNTAFLSLKSSVLRERASFCEDSSSDCDSSYFCFHSARICPGTRLTLQ
Sbjct: 181 QLLSQVGDLLCVGNTAFLSLKSSVLRERASFCEDSSSDCDSSYFCFHSARICPGTRLTLQ 240

Query: 241 PPSLSPMSRGCSSSIGALYVHHQVLDLIL 269
           PPSLSPMSRGCSSSIGALYVHHQVLDLIL
Sbjct: 241 PPSLSPMSRGCSSSIGALYVHHQVLDLIL 269


>gi|239756804 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 236

 Score = 32.0 bits (71), Expect = 0.58
 Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 15/73 (20%)

Query: 70  ALEALDLLLGLGGHAVGV-----AELD------LHLIEVSFHL----LLHPQGLVAAACL 114
           AL+ L LLLG    ++ V     A LD      LH   +  H     LLHP G VAA   
Sbjct: 47  ALQGLKLLLGWSPSSLSVFRGLQAFLDGLDLRQLHAHALPVHQCVQGLLHPSGRVAAQAR 106

Query: 115 CVQGGLQRVHHPQ 127
              GG+    HPQ
Sbjct: 107 AATGGVHPAGHPQ 119


>gi|239751298 PREDICTED: hypothetical protein XP_002347799 [Homo
           sapiens]
          Length = 236

 Score = 32.0 bits (71), Expect = 0.58
 Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 15/73 (20%)

Query: 70  ALEALDLLLGLGGHAVGV-----AELD------LHLIEVSFHL----LLHPQGLVAAACL 114
           AL+ L LLLG    ++ V     A LD      LH   +  H     LLHP G VAA   
Sbjct: 47  ALQGLKLLLGWSPSSLSVFRGLQAFLDGLDLRQLHAHALPVHQCVQGLLHPSGRVAAQAR 106

Query: 115 CVQGGLQRVHHPQ 127
              GG+    HPQ
Sbjct: 107 AATGGVHPAGHPQ 119


>gi|239745795 PREDICTED: hypothetical protein XP_002343591 [Homo
           sapiens]
          Length = 236

 Score = 32.0 bits (71), Expect = 0.58
 Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 15/73 (20%)

Query: 70  ALEALDLLLGLGGHAVGV-----AELD------LHLIEVSFHL----LLHPQGLVAAACL 114
           AL+ L LLLG    ++ V     A LD      LH   +  H     LLHP G VAA   
Sbjct: 47  ALQGLKLLLGWSPSSLSVFRGLQAFLDGLDLRQLHAHALPVHQCVQGLLHPSGRVAAQAR 106

Query: 115 CVQGGLQRVHHPQ 127
              GG+    HPQ
Sbjct: 107 AATGGVHPAGHPQ 119


>gi|239747203 PREDICTED: hypothetical protein LOC643965 [Homo
           sapiens]
          Length = 451

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 7/64 (10%)

Query: 2   QQL-HPLTSL-NQLLLRQLPGPLCLLHHGTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCI 59
           QQL HP  S+   L+ R  P P+   H G  L Q + Q  VAP H      QV  G  C+
Sbjct: 223 QQLGHPRVSVPGGLVQRGAPRPVHRAHRGPSLQQETHQGRVAPQHG-----QVERGPACV 277

Query: 60  VQLN 63
           V L+
Sbjct: 278 VHLS 281


>gi|239741003 PREDICTED: hypothetical protein LOC643965 [Homo
           sapiens]
          Length = 487

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 7/64 (10%)

Query: 2   QQL-HPLTSL-NQLLLRQLPGPLCLLHHGTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCI 59
           QQL HP  S+   L+ R  P P+   H G  L Q + Q  VAP H      QV  G  C+
Sbjct: 223 QQLGHPRVSVPGGLVQRGAPRPVHRAHRGPSLQQETHQGRVAPQHG-----QVERGPACV 277

Query: 60  VQLN 63
           V L+
Sbjct: 278 VHLS 281


>gi|239755210 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 241

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 52/180 (28%), Positives = 71/180 (39%), Gaps = 44/180 (24%)

Query: 18  LPGPLCLLHHGTQ----LLQLSLQQVVAPLHDGDVLLQVVVGTDCIVQLNLGYLQQALEA 73
           L G L LLH G +    LLQL  Q +  PL  G   LQ V+                  A
Sbjct: 85  LDGGLQLLHPGLEQGLLLLQLPQQLLAGPLLHGVPELQRVL------------------A 126

Query: 74  LDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGGLQRVHHPQVVALGL 133
           L L + LG H   +  ++L  ++V+   + H +G +          L R  H QVV L L
Sbjct: 127 LHLAVVLGLHEAVLELVNLQKLQVT---VPHERGALLLT-------LVRQAHGQVVVLLL 176

Query: 134 FHLLVLLCQLPLDLCLDLVELQLGPEDLALLLLSDLL---QLMDSLSAGTQLLSQVGDLL 190
                      L+L    + L L P    L+L    +   QL+D +  G Q   QV  LL
Sbjct: 177 ---------AALELAAAGLALLLEPLHTLLVLAQQAVLHPQLLDEVIFGAQQRGQVLHLL 227


>gi|239749699 PREDICTED: hypothetical protein XP_002347122 [Homo
           sapiens]
          Length = 241

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 52/180 (28%), Positives = 71/180 (39%), Gaps = 44/180 (24%)

Query: 18  LPGPLCLLHHGTQ----LLQLSLQQVVAPLHDGDVLLQVVVGTDCIVQLNLGYLQQALEA 73
           L G L LLH G +    LLQL  Q +  PL  G   LQ V+                  A
Sbjct: 85  LDGGLQLLHPGLEQGLLLLQLPQQLLAGPLLHGVPELQRVL------------------A 126

Query: 74  LDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGGLQRVHHPQVVALGL 133
           L L + LG H   +  ++L  ++V+   + H +G +          L R  H QVV L L
Sbjct: 127 LHLAVVLGLHEAVLELVNLQKLQVT---VPHERGALLLT-------LVRQAHGQVVVLLL 176

Query: 134 FHLLVLLCQLPLDLCLDLVELQLGPEDLALLLLSDLL---QLMDSLSAGTQLLSQVGDLL 190
                      L+L    + L L P    L+L    +   QL+D +  G Q   QV  LL
Sbjct: 177 ---------AALELAAAGLALLLEPLHTLLVLAQQAVLHPQLLDEVIFGAQQRGQVLHLL 227


>gi|239743965 PREDICTED: hypothetical protein XP_002344250 [Homo
           sapiens]
          Length = 241

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 52/180 (28%), Positives = 71/180 (39%), Gaps = 44/180 (24%)

Query: 18  LPGPLCLLHHGTQ----LLQLSLQQVVAPLHDGDVLLQVVVGTDCIVQLNLGYLQQALEA 73
           L G L LLH G +    LLQL  Q +  PL  G   LQ V+                  A
Sbjct: 85  LDGGLQLLHPGLEQGLLLLQLPQQLLAGPLLHGVPELQRVL------------------A 126

Query: 74  LDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGGLQRVHHPQVVALGL 133
           L L + LG H   +  ++L  ++V+   + H +G +          L R  H QVV L L
Sbjct: 127 LHLAVVLGLHEAVLELVNLQKLQVT---VPHERGALLLT-------LVRQAHGQVVVLLL 176

Query: 134 FHLLVLLCQLPLDLCLDLVELQLGPEDLALLLLSDLL---QLMDSLSAGTQLLSQVGDLL 190
                      L+L    + L L P    L+L    +   QL+D +  G Q   QV  LL
Sbjct: 177 ---------AALELAAAGLALLLEPLHTLLVLAQQAVLHPQLLDEVIFGAQQRGQVLHLL 227


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 14/43 (32%), Positives = 20/43 (46%), Gaps = 2/43 (4%)

Query: 211  FCEDSSSDCDSSYFCFHSARICPGTRLTLQPPSLSPMSRGCSS 253
            +CE S   C+    CF S    PG      PP+L+   R C++
Sbjct: 4942 YCEGSEDACEEP--CFPSVHCVPGKGCEACPPNLTGDGRHCAA 4982


>gi|112382231 mucin 4 isoform e [Homo sapiens]
          Length = 1125

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 14/43 (32%), Positives = 20/43 (46%), Gaps = 2/43 (4%)

Query: 211 FCEDSSSDCDSSYFCFHSARICPGTRLTLQPPSLSPMSRGCSS 253
           +CE S   C+    CF S    PG      PP+L+   R C++
Sbjct: 783 YCEGSEDACEEP--CFPSVHCVPGKGCEACPPNLTGDGRHCAA 823


>gi|112382233 mucin 4 isoform d [Homo sapiens]
          Length = 1176

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 14/43 (32%), Positives = 20/43 (46%), Gaps = 2/43 (4%)

Query: 211 FCEDSSSDCDSSYFCFHSARICPGTRLTLQPPSLSPMSRGCSS 253
           +CE S   C+    CF S    PG      PP+L+   R C++
Sbjct: 834 YCEGSEDACEEP--CFPSVHCVPGKGCEACPPNLTGDGRHCAA 874


>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
            isoform 2 [Homo sapiens]
          Length = 4097

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 28/126 (22%)

Query: 2    QQLHPLTSLNQLLLRQLPGPLCLLHH--GTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCI 59
            +QLH    L+ +L    P     LHH  GT+LL L + + +AP   GD          C+
Sbjct: 1456 KQLHRAGLLHNIL----PSQSTDLHHSVGTELLSL-VYKGIAP---GDE-------RQCL 1500

Query: 60   VQLNLGYLQQALEALDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGG 119
              L+L   Q A   L+L    GG           L E    LLL+P  L  A+    QG 
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGG-----------LCERLVSLLLNPAVLSTASLGSSQGS 1549

Query: 120  LQRVHH 125
            +    H
Sbjct: 1550 VIHFSH 1555


>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
            isoform 1 [Homo sapiens]
          Length = 4128

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 28/126 (22%)

Query: 2    QQLHPLTSLNQLLLRQLPGPLCLLHH--GTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCI 59
            +QLH    L+ +L    P     LHH  GT+LL L + + +AP   GD          C+
Sbjct: 1456 KQLHRAGLLHNIL----PSQSTDLHHSVGTELLSL-VYKGIAP---GDE-------RQCL 1500

Query: 60   VQLNLGYLQQALEALDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGG 119
              L+L   Q A   L+L    GG           L E    LLL+P  L  A+    QG 
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGG-----------LCERLVSLLLNPAVLSTASLGSSQGS 1549

Query: 120  LQRVHH 125
            +    H
Sbjct: 1550 VIHFSH 1555


>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
            catalytic polypeptide [Homo sapiens]
          Length = 4096

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 28/126 (22%)

Query: 2    QQLHPLTSLNQLLLRQLPGPLCLLHH--GTQLLQLSLQQVVAPLHDGDVLLQVVVGTDCI 59
            +QLH    L+ +L    P     LHH  GT+LL L + + +AP   GD          C+
Sbjct: 1456 KQLHRAGLLHNIL----PSQSTDLHHSVGTELLSL-VYKGIAP---GDE-------RQCL 1500

Query: 60   VQLNLGYLQQALEALDLLLGLGGHAVGVAELDLHLIEVSFHLLLHPQGLVAAACLCVQGG 119
              L+L   Q A   L+L    GG           L E    LLL+P  L  A+    QG 
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGG-----------LCERLVSLLLNPAVLSTASLGSSQGS 1549

Query: 120  LQRVHH 125
            +    H
Sbjct: 1550 VIHFSH 1555


>gi|73747887 ADAM metallopeptidase domain 12 isoform 2 preproprotein
           [Homo sapiens]
          Length = 738

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 205 LRERASFCEDSSSDCDSSYFCFHSARICP 233
           L+   + C DSS+ CD   FC  ++  CP
Sbjct: 475 LKPAGTACRDSSNSCDLPEFCTGASPHCP 503


>gi|73747885 ADAM metallopeptidase domain 12 isoform 1 preproprotein
           [Homo sapiens]
          Length = 909

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 205 LRERASFCEDSSSDCDSSYFCFHSARICP 233
           L+   + C DSS+ CD   FC  ++  CP
Sbjct: 475 LKPAGTACRDSSNSCDLPEFCTGASPHCP 503


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 8/83 (9%)

Query: 136 LLVLLCQLPLDL-CLDLVELQLGPEDLALLLLSDLLQL-MDSLSAGTQLLSQVGDLLCVG 193
           +L  L QL LD  C  LV  QL P      LL DLL+   +++ AG Q+   + + LCV 
Sbjct: 44  VLSTLAQLLLDKDCTVLVGRQLRP------LLLDLLERNAEAIKAGGQINHDLHERLCVS 97

Query: 194 NTAFLSLKSSVLRERASFCEDSS 216
            +  +     VL     + +D+S
Sbjct: 98  MSKLIGNHPDVLPFALRYFKDTS 120


>gi|89242141 colon cancer-associated protein Mic1 [Homo sapiens]
          Length = 657

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 3/54 (5%)

Query: 32  LQLSLQQVVAPLHDG--DVLLQVVVGTDCIVQLNLGYLQQALEALDLLLGLGGH 83
           L LSL+    P H    D+L ++    D IV++ L    Q L AL  + G+GGH
Sbjct: 536 LLLSLESFYPPAHQLSLDMLKRLSTANDEIVEVLLSK-HQVLAALRFIRGIGGH 588


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.142    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,250,446
Number of Sequences: 37866
Number of extensions: 433433
Number of successful extensions: 1515
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1505
Number of HSP's gapped (non-prelim): 23
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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