Guide to the Human Genome
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Search of human proteins with 239749742

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749742 PREDICTED: hypothetical protein XP_002347147 [Homo
sapiens]
         (133 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755261 PREDICTED: hypothetical protein [Homo sapiens]           293   4e-80
gi|239749742 PREDICTED: hypothetical protein XP_002347147 [Homo ...   293   4e-80
gi|239743997 PREDICTED: hypothetical protein XP_002343013 [Homo ...   293   4e-80
gi|76496497 artemis protein isoform a [Homo sapiens]                  200   3e-52
gi|76496495 artemis protein isoform b [Homo sapiens]                  200   3e-52
gi|76496501 artemis protein isoform c [Homo sapiens]                  200   3e-52
gi|76496499 artemis protein isoform d [Homo sapiens]                  200   3e-52
gi|223278374 DNA cross-link repair 1A [Homo sapiens]                   34   0.030
gi|65288071 tensin 3 [Homo sapiens]                                    29   1.3  
gi|57222563 colonic and hepatic tumor over-expressed protein iso...    29   1.3  
gi|57164942 colonic and hepatic tumor over-expressed protein iso...    29   1.3  
gi|38787970 tensin like C1 domain containing phosphatase isoform...    27   3.7  
gi|38787957 tensin like C1 domain containing phosphatase isoform...    27   3.7  
gi|38787941 tensin like C1 domain containing phosphatase isoform...    27   3.7  
gi|12383082 DNA cross-link repair 1B (PSO2 homolog, S. cerevisia...    27   4.8  
gi|170932467 phytoceramidase, alkaline [Homo sapiens]                  27   4.8  
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    27   6.3  
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    27   6.3  

>gi|239755261 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 133

 Score =  293 bits (749), Expect = 4e-80
 Identities = 133/133 (100%), Positives = 133/133 (100%)

Query: 1   MELSCTQGTSDWCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELV 60
           MELSCTQGTSDWCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELV
Sbjct: 1   MELSCTQGTSDWCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELV 60

Query: 61  QSWITQSLYHVVWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRN 120
           QSWITQSLYHVVWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRN
Sbjct: 61  QSWITQSLYHVVWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRN 120

Query: 121 TQIHAWWHPKVHV 133
           TQIHAWWHPKVHV
Sbjct: 121 TQIHAWWHPKVHV 133


>gi|239749742 PREDICTED: hypothetical protein XP_002347147 [Homo
           sapiens]
          Length = 133

 Score =  293 bits (749), Expect = 4e-80
 Identities = 133/133 (100%), Positives = 133/133 (100%)

Query: 1   MELSCTQGTSDWCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELV 60
           MELSCTQGTSDWCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELV
Sbjct: 1   MELSCTQGTSDWCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELV 60

Query: 61  QSWITQSLYHVVWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRN 120
           QSWITQSLYHVVWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRN
Sbjct: 61  QSWITQSLYHVVWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRN 120

Query: 121 TQIHAWWHPKVHV 133
           TQIHAWWHPKVHV
Sbjct: 121 TQIHAWWHPKVHV 133


>gi|239743997 PREDICTED: hypothetical protein XP_002343013 [Homo
           sapiens]
          Length = 133

 Score =  293 bits (749), Expect = 4e-80
 Identities = 133/133 (100%), Positives = 133/133 (100%)

Query: 1   MELSCTQGTSDWCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELV 60
           MELSCTQGTSDWCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELV
Sbjct: 1   MELSCTQGTSDWCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELV 60

Query: 61  QSWITQSLYHVVWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRN 120
           QSWITQSLYHVVWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRN
Sbjct: 61  QSWITQSLYHVVWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRN 120

Query: 121 TQIHAWWHPKVHV 133
           TQIHAWWHPKVHV
Sbjct: 121 TQIHAWWHPKVHV 133


>gi|76496497 artemis protein isoform a [Homo sapiens]
          Length = 692

 Score =  200 bits (508), Expect = 3e-52
 Identities = 93/103 (90%), Positives = 97/103 (94%)

Query: 28  DIQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHVVWLNCKAAYGYEYLFT 87
           DIQSVYLDT  CDPRFYQIPS+EECL GVLELV+SWIT+S YHVVWLNCKAAYGYEYLFT
Sbjct: 158 DIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFT 217

Query: 88  NLSEELGVQIHVNKLDMFRNMPEILHHLTTDRNTQIHAWWHPK 130
           NLSEELGVQ+HVNKLDMFRNMPEILHHLTTDRNTQIHA  HPK
Sbjct: 218 NLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQIHACRHPK 260


>gi|76496495 artemis protein isoform b [Homo sapiens]
          Length = 577

 Score =  200 bits (508), Expect = 3e-52
 Identities = 93/103 (90%), Positives = 97/103 (94%)

Query: 28  DIQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHVVWLNCKAAYGYEYLFT 87
           DIQSVYLDT  CDPRFYQIPS+EECL GVLELV+SWIT+S YHVVWLNCKAAYGYEYLFT
Sbjct: 43  DIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFT 102

Query: 88  NLSEELGVQIHVNKLDMFRNMPEILHHLTTDRNTQIHAWWHPK 130
           NLSEELGVQ+HVNKLDMFRNMPEILHHLTTDRNTQIHA  HPK
Sbjct: 103 NLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQIHACRHPK 145


>gi|76496501 artemis protein isoform c [Homo sapiens]
          Length = 572

 Score =  200 bits (508), Expect = 3e-52
 Identities = 93/103 (90%), Positives = 97/103 (94%)

Query: 28  DIQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHVVWLNCKAAYGYEYLFT 87
           DIQSVYLDT  CDPRFYQIPS+EECL GVLELV+SWIT+S YHVVWLNCKAAYGYEYLFT
Sbjct: 38  DIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFT 97

Query: 88  NLSEELGVQIHVNKLDMFRNMPEILHHLTTDRNTQIHAWWHPK 130
           NLSEELGVQ+HVNKLDMFRNMPEILHHLTTDRNTQIHA  HPK
Sbjct: 98  NLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQIHACRHPK 140


>gi|76496499 artemis protein isoform d [Homo sapiens]
          Length = 572

 Score =  200 bits (508), Expect = 3e-52
 Identities = 93/103 (90%), Positives = 97/103 (94%)

Query: 28  DIQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHVVWLNCKAAYGYEYLFT 87
           DIQSVYLDT  CDPRFYQIPS+EECL GVLELV+SWIT+S YHVVWLNCKAAYGYEYLFT
Sbjct: 38  DIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFT 97

Query: 88  NLSEELGVQIHVNKLDMFRNMPEILHHLTTDRNTQIHAWWHPK 130
           NLSEELGVQ+HVNKLDMFRNMPEILHHLTTDRNTQIHA  HPK
Sbjct: 98  NLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQIHACRHPK 140


>gi|223278374 DNA cross-link repair 1A [Homo sapiens]
          Length = 1040

 Score = 34.3 bits (77), Expect = 0.030
 Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 29  IQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHVVWLNCKAAYGYEYLFTN 88
           +  +YLDT  C P  Y  PSQ+E +   +      +T +  H + +    + G E +F  
Sbjct: 832 VHMLYLDTTYCSPE-YTFPSQQEVIRFAINTAFEAVTLN-PHALVVCGTYSIGKEKVFLA 889

Query: 89  LSEELGVQIHVN----KLDMFRNMPEILHHLTTD 118
           +++ LG ++ ++    K     N+PEI   +TTD
Sbjct: 890 IADVLGSKVGMSQEKYKTLQCLNIPEINSLITTD 923


>gi|65288071 tensin 3 [Homo sapiens]
          Length = 1445

 Score = 28.9 bits (63), Expect = 1.3
 Identities = 9/29 (31%), Positives = 18/29 (62%)

Query: 53  LCGVLELVQSWITQSLYHVVWLNCKAAYG 81
           +C + +  +SW+  +L HVV ++C+   G
Sbjct: 84  MCTICKAQESWLNSNLQHVVVIHCRGGKG 112


>gi|57222563 colonic and hepatic tumor over-expressed protein isoform
            b [Homo sapiens]
          Length = 1972

 Score = 28.9 bits (63), Expect = 1.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 23/100 (23%)

Query: 16   KLLEWSFCTPGAD-IQSVYLDTMLCDPRFYQ---------------------IPSQEECL 53
            K+L+W+F TP  + I+ +      C  ++ Q                     + S++E +
Sbjct: 1179 KVLKWNFTTPRDEYIEQLKTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGV 1238

Query: 54   CGVLELVQSWITQSLYHV-VWLNCKAAYGYEYLFTNLSEE 92
             G L+L+  W+T   +     +  KA    + LFT LSEE
Sbjct: 1239 IGCLDLILKWLTLRFFDTNTSVLMKALEYLKLLFTLLSEE 1278


>gi|57164942 colonic and hepatic tumor over-expressed protein isoform
            a [Homo sapiens]
          Length = 2032

 Score = 28.9 bits (63), Expect = 1.3
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 23/100 (23%)

Query: 16   KLLEWSFCTPGAD-IQSVYLDTMLCDPRFYQ---------------------IPSQEECL 53
            K+L+W+F TP  + I+ +      C  ++ Q                     + S++E +
Sbjct: 1179 KVLKWNFTTPRDEYIEQLKTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGV 1238

Query: 54   CGVLELVQSWITQSLYHV-VWLNCKAAYGYEYLFTNLSEE 92
             G L+L+  W+T   +     +  KA    + LFT LSEE
Sbjct: 1239 IGCLDLILKWLTLRFFDTNTSVLMKALEYLKLLFTLLSEE 1278


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score = 27.3 bits (59), Expect = 3.7
 Identities = 10/29 (34%), Positives = 17/29 (58%)

Query: 53  LCGVLELVQSWITQSLYHVVWLNCKAAYG 81
           LC + + +++W++    HVV L CK   G
Sbjct: 84  LCSICKAMETWLSADPQHVVVLYCKGNKG 112


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
           [Homo sapiens]
          Length = 1409

 Score = 27.3 bits (59), Expect = 3.7
 Identities = 10/29 (34%), Positives = 17/29 (58%)

Query: 53  LCGVLELVQSWITQSLYHVVWLNCKAAYG 81
           LC + + +++W++    HVV L CK   G
Sbjct: 208 LCSICKAMETWLSADPQHVVVLYCKGNKG 236


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
           [Homo sapiens]
          Length = 1419

 Score = 27.3 bits (59), Expect = 3.7
 Identities = 10/29 (34%), Positives = 17/29 (58%)

Query: 53  LCGVLELVQSWITQSLYHVVWLNCKAAYG 81
           LC + + +++W++    HVV L CK   G
Sbjct: 218 LCSICKAMETWLSADPQHVVVLYCKGNKG 246


>gi|12383082 DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae)
           [Homo sapiens]
          Length = 532

 Score = 26.9 bits (58), Expect = 4.8
 Identities = 12/38 (31%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 24  TPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQ 61
           T G  I ++YLD   C+P    +PS++E    +++L++
Sbjct: 134 TLGKQIHTLYLDNTNCNPALV-LPSRQEAAHQIVQLIR 170


>gi|170932467 phytoceramidase, alkaline [Homo sapiens]
          Length = 267

 Score = 26.9 bits (58), Expect = 4.8
 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 28/109 (25%)

Query: 29  IQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHVVWLN-CKAAYGYE---- 83
           + +VYL     +P F+Q+      + G+L  V + + +S+Y V W+       GY     
Sbjct: 132 VTTVYLKVK--EPIFHQV------MYGML--VFTLVLRSIYIVTWVYPWLRGLGYTSLGI 181

Query: 84  ----YLFTNLSEELGVQIHVNKLDMFRNMPEILHHLTTDRNTQIHAWWH 128
               +LF N+       I    L  FR     +  +TT    Q HAWWH
Sbjct: 182 FLLGFLFWNIDN-----IFCESLRNFRKKVPPIIGITT----QFHAWWH 221


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 26.6 bits (57), Expect = 6.3
 Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 18/99 (18%)

Query: 12   WCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHV 71
            WC+E   EW F +   + +++ LD +           QEE L  + +  ++  T+ L  +
Sbjct: 3463 WCEELKQEWKFVSEEIEREAIILDNL-----------QEE-LPEISKTKEAATTEELSEL 3510

Query: 72   VWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPE 110
              L+C   YG         ++L + + + ++   +N+PE
Sbjct: 3511 --LDCLCQYGENV----EKQQLLLTLLLQRIRSIQNVPE 3543


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 26.6 bits (57), Expect = 6.3
 Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 18/99 (18%)

Query: 12   WCKEKLLEWSFCTPGADIQSVYLDTMLCDPRFYQIPSQEECLCGVLELVQSWITQSLYHV 71
            WC+E   EW F +   + +++ LD +           QEE L  + +  ++  T+ L  +
Sbjct: 3463 WCEELKQEWKFVSEEIEREAIILDNL-----------QEE-LPEISKTKEAATTEELSEL 3510

Query: 72   VWLNCKAAYGYEYLFTNLSEELGVQIHVNKLDMFRNMPE 110
              L+C   YG         ++L + + + ++   +N+PE
Sbjct: 3511 --LDCLCQYGENV----EKQQLLLTLLLQRIRSIQNVPE 3543


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.136    0.469 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,750,999
Number of Sequences: 37866
Number of extensions: 229280
Number of successful extensions: 545
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 533
Number of HSP's gapped (non-prelim): 19
length of query: 133
length of database: 18,247,518
effective HSP length: 91
effective length of query: 42
effective length of database: 14,801,712
effective search space: 621671904
effective search space used: 621671904
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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